-- dump date   	20140619_230910
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1123863000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1123863000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1123863000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863000004	Walker A motif; other site
1123863000005	ATP binding site [chemical binding]; other site
1123863000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1123863000007	Walker B motif; other site
1123863000008	arginine finger; other site
1123863000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1123863000010	DnaA box-binding interface [nucleotide binding]; other site
1123863000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
1123863000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1123863000013	putative DNA binding surface [nucleotide binding]; other site
1123863000014	dimer interface [polypeptide binding]; other site
1123863000015	beta-clamp/clamp loader binding surface; other site
1123863000016	beta-clamp/translesion DNA polymerase binding surface; other site
1123863000017	recF protein; Region: recf; TIGR00611
1123863000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863000019	Walker A/P-loop; other site
1123863000020	ATP binding site [chemical binding]; other site
1123863000021	Q-loop/lid; other site
1123863000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863000023	ABC transporter signature motif; other site
1123863000024	Walker B; other site
1123863000025	D-loop; other site
1123863000026	H-loop/switch region; other site
1123863000027	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1123863000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863000029	Mg2+ binding site [ion binding]; other site
1123863000030	G-X-G motif; other site
1123863000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1123863000032	anchoring element; other site
1123863000033	dimer interface [polypeptide binding]; other site
1123863000034	ATP binding site [chemical binding]; other site
1123863000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1123863000036	active site
1123863000037	putative metal-binding site [ion binding]; other site
1123863000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1123863000039	sugar phosphate phosphatase; Provisional; Region: PRK10513
1123863000040	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863000041	active site
1123863000042	motif I; other site
1123863000043	motif II; other site
1123863000044	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863000045	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1123863000046	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1123863000047	Protein of unknown function (DUF1375); Region: DUF1375; cl11456
1123863000048	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1123863000049	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1123863000050	putative dimer interface [polypeptide binding]; other site
1123863000051	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1123863000052	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1123863000053	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
1123863000054	2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase hydrolyzes PDC to yield 4-oxalomesaconic acid (OMA) or its tautomer, 4-carboxy-2-hydroxymuconic acid (CHM). This reaction is part of the protocatechuate (PCA) 4,5-cleavage pathway. PCA is one of the most...; Region: PDC_hydrolase; cd01311
1123863000055	active site
1123863000056	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1123863000057	EamA-like transporter family; Region: EamA; pfam00892
1123863000058	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1123863000059	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863000060	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863000061	homodimer interface [polypeptide binding]; other site
1123863000062	catalytic residue [active]
1123863000063	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1123863000064	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1123863000065	dimerization interface [polypeptide binding]; other site
1123863000066	ligand binding site [chemical binding]; other site
1123863000067	NADP binding site [chemical binding]; other site
1123863000068	catalytic site [active]
1123863000069	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000070	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863000071	putative substrate translocation pore; other site
1123863000072	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863000073	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1123863000074	substrate binding site [chemical binding]; other site
1123863000075	ATP binding site [chemical binding]; other site
1123863000076	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1123863000077	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863000078	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863000079	DNA binding site [nucleotide binding]
1123863000080	domain linker motif; other site
1123863000081	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
1123863000082	putative dimerization interface [polypeptide binding]; other site
1123863000083	putative ligand binding site [chemical binding]; other site
1123863000084	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863000085	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863000086	DNA binding site [nucleotide binding]
1123863000087	domain linker motif; other site
1123863000088	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
1123863000089	ligand binding site [chemical binding]; other site
1123863000090	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1123863000091	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1123863000092	ligand binding site [chemical binding]; other site
1123863000093	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1123863000094	primosomal protein DnaI; Provisional; Region: PRK02854
1123863000095	DNA replication protein DnaC; Validated; Region: PRK07952
1123863000096	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863000097	Walker A motif; other site
1123863000098	ATP binding site [chemical binding]; other site
1123863000099	Walker B motif; other site
1123863000100	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1123863000101	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1123863000102	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863000103	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863000104	DNA binding site [nucleotide binding]
1123863000105	domain linker motif; other site
1123863000106	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1123863000107	ligand binding site [chemical binding]; other site
1123863000108	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1123863000109	active site
1123863000110	P-loop; other site
1123863000111	phosphorylation site [posttranslational modification]
1123863000112	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1123863000113	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1123863000114	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1123863000115	beta-galactosidase; Region: BGL; TIGR03356
1123863000116	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1123863000117	methionine cluster; other site
1123863000118	active site
1123863000119	phosphorylation site [posttranslational modification]
1123863000120	metal binding site [ion binding]; metal-binding site
1123863000121	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1123863000122	citrate-proton symporter; Provisional; Region: PRK15075
1123863000123	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000124	putative substrate translocation pore; other site
1123863000125	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1123863000126	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1123863000127	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863000128	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863000129	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1123863000130	putative dimerization interface [polypeptide binding]; other site
1123863000131	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863000132	PAS domain; Region: PAS_9; pfam13426
1123863000133	putative active site [active]
1123863000134	heme pocket [chemical binding]; other site
1123863000135	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863000136	PAS domain; Region: PAS_9; pfam13426
1123863000137	putative active site [active]
1123863000138	heme pocket [chemical binding]; other site
1123863000139	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863000140	dimer interface [polypeptide binding]; other site
1123863000141	putative CheW interface [polypeptide binding]; other site
1123863000142	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863000143	Putative motility protein; Region: YjfB_motility; pfam14070
1123863000144	outer membrane protease; Reviewed; Region: PRK10993
1123863000145	OsmC-like protein; Region: OsmC; cl00767
1123863000146	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
1123863000147	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863000148	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1123863000149	putative active site [active]
1123863000150	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863000151	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863000152	TM-ABC transporter signature motif; other site
1123863000153	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863000154	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863000155	TM-ABC transporter signature motif; other site
1123863000156	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863000157	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863000158	Walker A/P-loop; other site
1123863000159	ATP binding site [chemical binding]; other site
1123863000160	Q-loop/lid; other site
1123863000161	ABC transporter signature motif; other site
1123863000162	Walker B; other site
1123863000163	D-loop; other site
1123863000164	H-loop/switch region; other site
1123863000165	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863000166	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1123863000167	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1123863000168	ligand binding site [chemical binding]; other site
1123863000169	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1123863000170	active site
1123863000171	catalytic residues [active]
1123863000172	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1123863000173	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863000174	Coenzyme A binding pocket [chemical binding]; other site
1123863000175	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1123863000176	putative dimerization interface [polypeptide binding]; other site
1123863000177	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863000178	putative ligand binding site [chemical binding]; other site
1123863000179	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863000180	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1123863000181	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863000182	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1123863000183	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863000184	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863000185	TM-ABC transporter signature motif; other site
1123863000186	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
1123863000187	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863000188	Walker A/P-loop; other site
1123863000189	ATP binding site [chemical binding]; other site
1123863000190	Q-loop/lid; other site
1123863000191	ABC transporter signature motif; other site
1123863000192	Walker B; other site
1123863000193	D-loop; other site
1123863000194	H-loop/switch region; other site
1123863000195	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863000196	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
1123863000197	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1123863000198	putative ligand binding site [chemical binding]; other site
1123863000199	xylose isomerase; Provisional; Region: PRK05474
1123863000200	xylose isomerase; Region: xylose_isom_A; TIGR02630
1123863000201	xylulokinase; Provisional; Region: PRK15027
1123863000202	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1123863000203	N- and C-terminal domain interface [polypeptide binding]; other site
1123863000204	active site
1123863000205	MgATP binding site [chemical binding]; other site
1123863000206	catalytic site [active]
1123863000207	metal binding site [ion binding]; metal-binding site
1123863000208	xylulose binding site [chemical binding]; other site
1123863000209	homodimer interface [polypeptide binding]; other site
1123863000210	benzoate transport; Region: 2A0115; TIGR00895
1123863000211	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000212	putative substrate translocation pore; other site
1123863000213	transcriptional regulator PhoU; Provisional; Region: PRK11115
1123863000214	PhoU domain; Region: PhoU; pfam01895
1123863000215	PhoU domain; Region: PhoU; pfam01895
1123863000216	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1123863000217	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1123863000218	Walker A/P-loop; other site
1123863000219	ATP binding site [chemical binding]; other site
1123863000220	Q-loop/lid; other site
1123863000221	ABC transporter signature motif; other site
1123863000222	Walker B; other site
1123863000223	D-loop; other site
1123863000224	H-loop/switch region; other site
1123863000225	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1123863000226	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863000227	dimer interface [polypeptide binding]; other site
1123863000228	conserved gate region; other site
1123863000229	putative PBP binding loops; other site
1123863000230	ABC-ATPase subunit interface; other site
1123863000231	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1123863000232	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863000233	dimer interface [polypeptide binding]; other site
1123863000234	conserved gate region; other site
1123863000235	putative PBP binding loops; other site
1123863000236	ABC-ATPase subunit interface; other site
1123863000237	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863000238	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
1123863000239	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1123863000240	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1123863000241	glutaminase active site [active]
1123863000242	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1123863000243	dimer interface [polypeptide binding]; other site
1123863000244	active site
1123863000245	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1123863000246	dimer interface [polypeptide binding]; other site
1123863000247	active site
1123863000248	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1123863000249	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1123863000250	Substrate binding site; other site
1123863000251	Mg++ binding site; other site
1123863000252	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1123863000253	active site
1123863000254	substrate binding site [chemical binding]; other site
1123863000255	CoA binding site [chemical binding]; other site
1123863000256	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1123863000257	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1123863000258	gamma subunit interface [polypeptide binding]; other site
1123863000259	epsilon subunit interface [polypeptide binding]; other site
1123863000260	LBP interface [polypeptide binding]; other site
1123863000261	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1123863000262	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1123863000263	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1123863000264	alpha subunit interaction interface [polypeptide binding]; other site
1123863000265	Walker A motif; other site
1123863000266	ATP binding site [chemical binding]; other site
1123863000267	Walker B motif; other site
1123863000268	inhibitor binding site; inhibition site
1123863000269	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1123863000270	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1123863000271	core domain interface [polypeptide binding]; other site
1123863000272	delta subunit interface [polypeptide binding]; other site
1123863000273	epsilon subunit interface [polypeptide binding]; other site
1123863000274	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1123863000275	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1123863000276	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1123863000277	Walker A motif; other site
1123863000278	ATP binding site [chemical binding]; other site
1123863000279	Walker B motif; other site
1123863000280	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1123863000281	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1123863000282	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1123863000283	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1123863000284	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1123863000285	ATP synthase, F0 subunit c; Region: ATP_synt_c; TIGR01260
1123863000286	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1123863000287	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1123863000288	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1123863000289	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1123863000290	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863000291	S-adenosylmethionine binding site [chemical binding]; other site
1123863000292	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1123863000293	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1123863000294	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1123863000295	FMN-binding protein MioC; Provisional; Region: PRK09004
1123863000296	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1123863000297	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863000298	putative DNA binding site [nucleotide binding]; other site
1123863000299	putative Zn2+ binding site [ion binding]; other site
1123863000300	AsnC family; Region: AsnC_trans_reg; pfam01037
1123863000301	5-histidylcysteine sulfoxide synthase; Region: ovoA_Nterm; TIGR04344
1123863000302	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
1123863000303	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1123863000304	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863000305	S-adenosylmethionine binding site [chemical binding]; other site
1123863000306	hypothetical protein; Provisional; Region: yieM; PRK10997
1123863000307	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1123863000308	metal ion-dependent adhesion site (MIDAS); other site
1123863000309	regulatory ATPase RavA; Provisional; Region: PRK13531
1123863000310	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863000311	Walker A motif; other site
1123863000312	ATP binding site [chemical binding]; other site
1123863000313	Walker B motif; other site
1123863000314	arginine finger; other site
1123863000315	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1123863000316	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1123863000317	potassium uptake protein; Region: kup; TIGR00794
1123863000318	sensor protein QseC; Provisional; Region: PRK10337
1123863000319	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863000320	dimer interface [polypeptide binding]; other site
1123863000321	phosphorylation site [posttranslational modification]
1123863000322	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863000323	ATP binding site [chemical binding]; other site
1123863000324	Mg2+ binding site [ion binding]; other site
1123863000325	G-X-G motif; other site
1123863000326	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1123863000327	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863000328	active site
1123863000329	phosphorylation site [posttranslational modification]
1123863000330	intermolecular recognition site; other site
1123863000331	dimerization interface [polypeptide binding]; other site
1123863000332	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863000333	DNA binding site [nucleotide binding]
1123863000334	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1123863000335	D-ribose pyranase; Provisional; Region: PRK11797
1123863000336	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1123863000337	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863000338	Walker A/P-loop; other site
1123863000339	ATP binding site [chemical binding]; other site
1123863000340	Q-loop/lid; other site
1123863000341	ABC transporter signature motif; other site
1123863000342	Walker B; other site
1123863000343	D-loop; other site
1123863000344	H-loop/switch region; other site
1123863000345	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863000346	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863000347	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863000348	TM-ABC transporter signature motif; other site
1123863000349	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1123863000350	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1123863000351	ligand binding site [chemical binding]; other site
1123863000352	dimerization interface [polypeptide binding]; other site
1123863000353	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863000354	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1123863000355	substrate binding site [chemical binding]; other site
1123863000356	dimer interface [polypeptide binding]; other site
1123863000357	ATP binding site [chemical binding]; other site
1123863000358	transcriptional repressor RbsR; Provisional; Region: PRK10423
1123863000359	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863000360	DNA binding site [nucleotide binding]
1123863000361	domain linker motif; other site
1123863000362	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1123863000363	dimerization interface [polypeptide binding]; other site
1123863000364	ligand binding site [chemical binding]; other site
1123863000365	putative transporter; Provisional; Region: PRK10504
1123863000366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000367	putative substrate translocation pore; other site
1123863000368	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000369	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1123863000370	Walker A motif; other site
1123863000371	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1123863000372	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1123863000373	GTP binding site; other site
1123863000374	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1123863000375	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1123863000376	serine/threonine protein kinase; Provisional; Region: PRK11768
1123863000377	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1123863000378	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1123863000379	catalytic residues [active]
1123863000380	hinge region; other site
1123863000381	alpha helical domain; other site
1123863000382	DNA polymerase I; Provisional; Region: PRK05755
1123863000383	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1123863000384	active site
1123863000385	metal binding site 1 [ion binding]; metal-binding site
1123863000386	putative 5' ssDNA interaction site; other site
1123863000387	metal binding site 3; metal-binding site
1123863000388	metal binding site 2 [ion binding]; metal-binding site
1123863000389	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1123863000390	putative DNA binding site [nucleotide binding]; other site
1123863000391	putative metal binding site [ion binding]; other site
1123863000392	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1123863000393	active site
1123863000394	catalytic site [active]
1123863000395	substrate binding site [chemical binding]; other site
1123863000396	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1123863000397	active site
1123863000398	DNA binding site [nucleotide binding]
1123863000399	catalytic site [active]
1123863000400	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1123863000401	G1 box; other site
1123863000402	GTP/Mg2+ binding site [chemical binding]; other site
1123863000403	Switch I region; other site
1123863000404	G2 box; other site
1123863000405	G3 box; other site
1123863000406	Switch II region; other site
1123863000407	G4 box; other site
1123863000408	G5 box; other site
1123863000409	Der GTPase activator; Provisional; Region: PRK05244
1123863000410	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1123863000411	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863000412	FeS/SAM binding site; other site
1123863000413	HemN C-terminal domain; Region: HemN_C; pfam06969
1123863000414	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1123863000415	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863000416	active site
1123863000417	phosphorylation site [posttranslational modification]
1123863000418	intermolecular recognition site; other site
1123863000419	dimerization interface [polypeptide binding]; other site
1123863000420	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863000421	Walker A motif; other site
1123863000422	ATP binding site [chemical binding]; other site
1123863000423	Walker B motif; other site
1123863000424	arginine finger; other site
1123863000425	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1123863000426	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1123863000427	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863000428	putative active site [active]
1123863000429	heme pocket [chemical binding]; other site
1123863000430	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863000431	dimer interface [polypeptide binding]; other site
1123863000432	phosphorylation site [posttranslational modification]
1123863000433	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863000434	ATP binding site [chemical binding]; other site
1123863000435	Mg2+ binding site [ion binding]; other site
1123863000436	G-X-G motif; other site
1123863000437	glutamine synthetase; Provisional; Region: glnA; PRK09469
1123863000438	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1123863000439	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1123863000440	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1123863000441	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1123863000442	G1 box; other site
1123863000443	putative GEF interaction site [polypeptide binding]; other site
1123863000444	GTP/Mg2+ binding site [chemical binding]; other site
1123863000445	Switch I region; other site
1123863000446	G2 box; other site
1123863000447	G3 box; other site
1123863000448	Switch II region; other site
1123863000449	G4 box; other site
1123863000450	G5 box; other site
1123863000451	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1123863000452	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1123863000453	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1123863000454	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863000455	motif II; other site
1123863000456	hypothetical protein; Reviewed; Region: PRK01637
1123863000457	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1123863000458	putative active site [active]
1123863000459	dimerization interface [polypeptide binding]; other site
1123863000460	putative tRNAtyr binding site [nucleotide binding]; other site
1123863000461	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863000462	Coenzyme A binding pocket [chemical binding]; other site
1123863000463	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1123863000464	AsmA family; Region: AsmA; pfam05170
1123863000465	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1123863000466	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1123863000467	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1123863000468	Y-family of DNA polymerases; Region: PolY; cl12025
1123863000469	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1123863000470	generic binding surface II; other site
1123863000471	ssDNA binding site; other site
1123863000472	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863000473	ATP binding site [chemical binding]; other site
1123863000474	putative Mg++ binding site [ion binding]; other site
1123863000475	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863000476	nucleotide binding region [chemical binding]; other site
1123863000477	ATP-binding site [chemical binding]; other site
1123863000478	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1123863000479	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1123863000480	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1123863000481	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1123863000482	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1123863000483	Zn2+ binding site [ion binding]; other site
1123863000484	Mg2+ binding site [ion binding]; other site
1123863000485	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1123863000486	synthetase active site [active]
1123863000487	NTP binding site [chemical binding]; other site
1123863000488	metal binding site [ion binding]; metal-binding site
1123863000489	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1123863000490	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1123863000491	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1123863000492	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1123863000493	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1123863000494	catalytic site [active]
1123863000495	G-X2-G-X-G-K; other site
1123863000496	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1123863000497	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1123863000498	nucleotide binding pocket [chemical binding]; other site
1123863000499	K-X-D-G motif; other site
1123863000500	catalytic site [active]
1123863000501	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1123863000502	Predicted membrane protein [Function unknown]; Region: COG2860
1123863000503	UPF0126 domain; Region: UPF0126; pfam03458
1123863000504	UPF0126 domain; Region: UPF0126; pfam03458
1123863000505	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1123863000506	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1123863000507	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1123863000508	putative acyl-acceptor binding pocket; other site
1123863000509	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
1123863000510	hypothetical protein; Provisional; Region: PRK11820
1123863000511	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1123863000512	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1123863000513	Protein of unknown function (DUF3574); Region: DUF3574; pfam12098
1123863000514	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1123863000515	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1123863000516	Nucleoside recognition; Region: Gate; pfam07670
1123863000517	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1123863000518	ribonuclease PH; Reviewed; Region: rph; PRK00173
1123863000519	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1123863000520	hexamer interface [polypeptide binding]; other site
1123863000521	active site
1123863000522	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1123863000523	active site
1123863000524	division inhibitor protein; Provisional; Region: slmA; PRK09480
1123863000525	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863000526	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1123863000527	trimer interface [polypeptide binding]; other site
1123863000528	active site
1123863000529	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1123863000530	Flavoprotein; Region: Flavoprotein; pfam02441
1123863000531	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1123863000532	hypothetical protein; Reviewed; Region: PRK00024
1123863000533	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1123863000534	MPN+ (JAMM) motif; other site
1123863000535	Zinc-binding site [ion binding]; other site
1123863000536	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1123863000537	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1123863000538	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1123863000539	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1123863000540	DNA binding site [nucleotide binding]
1123863000541	catalytic residue [active]
1123863000542	H2TH interface [polypeptide binding]; other site
1123863000543	putative catalytic residues [active]
1123863000544	turnover-facilitating residue; other site
1123863000545	intercalation triad [nucleotide binding]; other site
1123863000546	8OG recognition residue [nucleotide binding]; other site
1123863000547	putative reading head residues; other site
1123863000548	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1123863000549	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1123863000550	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1123863000551	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1123863000552	active site
1123863000553	(T/H)XGH motif; other site
1123863000554	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1123863000555	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1123863000556	putative metal binding site; other site
1123863000557	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1123863000558	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1123863000559	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1123863000560	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1123863000561	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1123863000562	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1123863000563	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1123863000564	putative active site [active]
1123863000565	putative glycosyl transferase; Provisional; Region: PRK10073
1123863000566	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1123863000567	active site
1123863000568	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1123863000569	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1123863000570	putative active site [active]
1123863000571	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1123863000572	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1123863000573	NAD binding site [chemical binding]; other site
1123863000574	homodimer interface [polypeptide binding]; other site
1123863000575	active site
1123863000576	substrate binding site [chemical binding]; other site
1123863000577	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1123863000578	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1123863000579	putative ADP-binding pocket [chemical binding]; other site
1123863000580	Putative catalytic domain of lipopolysaccharide biosynthesis protein WalW and its bacterial homologs; Region: CE4_WalW; cd10935
1123863000581	putative active site [active]
1123863000582	putative catalytic site [active]
1123863000583	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1123863000584	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1123863000585	putative active site [active]
1123863000586	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
1123863000587	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1123863000588	O-Antigen ligase; Region: Wzy_C; pfam04932
1123863000589	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1123863000590	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1123863000591	putative active site [active]
1123863000592	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1123863000593	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1123863000594	putative active site [active]
1123863000595	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1123863000596	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1123863000597	NADP binding site [chemical binding]; other site
1123863000598	homopentamer interface [polypeptide binding]; other site
1123863000599	substrate binding site [chemical binding]; other site
1123863000600	active site
1123863000601	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1123863000602	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1123863000603	substrate-cofactor binding pocket; other site
1123863000604	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863000605	catalytic residue [active]
1123863000606	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1123863000607	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1123863000608	NAD(P) binding site [chemical binding]; other site
1123863000609	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1123863000610	NodB motif; other site
1123863000611	putative active site [active]
1123863000612	putative catalytic site [active]
1123863000613	Zn binding site [ion binding]; other site
1123863000614	AmiB activator; Provisional; Region: PRK11637
1123863000615	Peptidase family M23; Region: Peptidase_M23; pfam01551
1123863000616	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1123863000617	active site residue [active]
1123863000618	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1123863000619	GSH binding site [chemical binding]; other site
1123863000620	catalytic residues [active]
1123863000621	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1123863000622	SecA binding site; other site
1123863000623	Preprotein binding site; other site
1123863000624	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1123863000625	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1123863000626	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1123863000627	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1123863000628	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1123863000629	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1123863000630	trimer interface [polypeptide binding]; other site
1123863000631	active site
1123863000632	substrate binding site [chemical binding]; other site
1123863000633	CoA binding site [chemical binding]; other site
1123863000634	putative rRNA methylase; Provisional; Region: PRK10358
1123863000635	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1123863000636	HAMP domain; Region: HAMP; pfam00672
1123863000637	dimerization interface [polypeptide binding]; other site
1123863000638	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1123863000639	dimer interface [polypeptide binding]; other site
1123863000640	phosphorylation site [posttranslational modification]
1123863000641	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863000642	ATP binding site [chemical binding]; other site
1123863000643	Mg2+ binding site [ion binding]; other site
1123863000644	G-X-G motif; other site
1123863000645	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1123863000646	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863000647	active site
1123863000648	intermolecular recognition site; other site
1123863000649	dimerization interface [polypeptide binding]; other site
1123863000650	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863000651	DNA binding site [nucleotide binding]
1123863000652	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1123863000653	dimer interface [polypeptide binding]; other site
1123863000654	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1123863000655	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1123863000656	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1123863000657	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1123863000658	active site
1123863000659	ADP/pyrophosphate binding site [chemical binding]; other site
1123863000660	dimerization interface [polypeptide binding]; other site
1123863000661	allosteric effector site; other site
1123863000662	fructose-1,6-bisphosphate binding site; other site
1123863000663	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1123863000664	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863000665	substrate binding pocket [chemical binding]; other site
1123863000666	membrane-bound complex binding site; other site
1123863000667	hinge residues; other site
1123863000668	CDP-diacylglycerol pyrophosphatase; Provisional; Region: PRK05471
1123863000669	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1123863000670	triosephosphate isomerase; Provisional; Region: PRK14567
1123863000671	substrate binding site [chemical binding]; other site
1123863000672	dimer interface [polypeptide binding]; other site
1123863000673	catalytic triad [active]
1123863000674	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1123863000675	Predicted membrane protein [Function unknown]; Region: COG3152
1123863000676	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1123863000677	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1123863000678	FAD binding pocket [chemical binding]; other site
1123863000679	FAD binding motif [chemical binding]; other site
1123863000680	phosphate binding motif [ion binding]; other site
1123863000681	beta-alpha-beta structure motif; other site
1123863000682	NAD binding pocket [chemical binding]; other site
1123863000683	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1123863000684	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000685	putative substrate translocation pore; other site
1123863000686	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1123863000687	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1123863000688	putative active site [active]
1123863000689	glycerol kinase; Provisional; Region: glpK; PRK00047
1123863000690	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1123863000691	N- and C-terminal domain interface [polypeptide binding]; other site
1123863000692	active site
1123863000693	MgATP binding site [chemical binding]; other site
1123863000694	catalytic site [active]
1123863000695	metal binding site [ion binding]; metal-binding site
1123863000696	glycerol binding site [chemical binding]; other site
1123863000697	homotetramer interface [polypeptide binding]; other site
1123863000698	homodimer interface [polypeptide binding]; other site
1123863000699	FBP binding site [chemical binding]; other site
1123863000700	protein IIAGlc interface [polypeptide binding]; other site
1123863000701	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1123863000702	amphipathic channel; other site
1123863000703	Asn-Pro-Ala signature motifs; other site
1123863000704	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3074
1123863000705	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1123863000706	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1123863000707	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863000708	Walker A motif; other site
1123863000709	ATP binding site [chemical binding]; other site
1123863000710	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1123863000711	Walker B motif; other site
1123863000712	arginine finger; other site
1123863000713	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1123863000714	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1123863000715	active site
1123863000716	HslU subunit interaction site [polypeptide binding]; other site
1123863000717	cell division protein FtsN; Provisional; Region: PRK12757
1123863000718	Sporulation related domain; Region: SPOR; cl10051
1123863000719	Sporulation related domain; Region: SPOR; cl10051
1123863000720	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863000721	DNA binding site [nucleotide binding]
1123863000722	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1123863000723	domain linker motif; other site
1123863000724	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1123863000725	dimerization interface [polypeptide binding]; other site
1123863000726	ligand binding site [chemical binding]; other site
1123863000727	primosome assembly protein PriA; Validated; Region: PRK05580
1123863000728	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863000729	ATP binding site [chemical binding]; other site
1123863000730	putative Mg++ binding site [ion binding]; other site
1123863000731	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1123863000732	ATP-binding site [chemical binding]; other site
1123863000733	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1123863000734	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1123863000735	dimerization interface [polypeptide binding]; other site
1123863000736	DNA binding site [nucleotide binding]
1123863000737	corepressor binding sites; other site
1123863000738	cystathionine gamma-synthase; Provisional; Region: PRK08045
1123863000739	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1123863000740	homodimer interface [polypeptide binding]; other site
1123863000741	substrate-cofactor binding pocket; other site
1123863000742	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863000743	catalytic residue [active]
1123863000744	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1123863000745	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1123863000746	putative catalytic residues [active]
1123863000747	putative nucleotide binding site [chemical binding]; other site
1123863000748	putative aspartate binding site [chemical binding]; other site
1123863000749	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1123863000750	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1123863000751	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1123863000752	FAD binding site [chemical binding]; other site
1123863000753	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863000754	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863000755	dimerization interface [polypeptide binding]; other site
1123863000756	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863000757	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863000758	dimer interface [polypeptide binding]; other site
1123863000759	putative CheW interface [polypeptide binding]; other site
1123863000760	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1123863000761	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1123863000762	acetylornithine deacetylase; Provisional; Region: PRK05111
1123863000763	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1123863000764	metal binding site [ion binding]; metal-binding site
1123863000765	putative dimer interface [polypeptide binding]; other site
1123863000766	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1123863000767	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1123863000768	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1123863000769	nucleotide binding site [chemical binding]; other site
1123863000770	N-acetyl-L-glutamate binding site [chemical binding]; other site
1123863000771	argininosuccinate synthase; Provisional; Region: PRK13820
1123863000772	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1123863000773	ANP binding site [chemical binding]; other site
1123863000774	Substrate Binding Site II [chemical binding]; other site
1123863000775	Substrate Binding Site I [chemical binding]; other site
1123863000776	argininosuccinate lyase; Provisional; Region: PRK04833
1123863000777	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1123863000778	active sites [active]
1123863000779	tetramer interface [polypeptide binding]; other site
1123863000780	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1123863000781	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863000782	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1123863000783	dimerization interface [polypeptide binding]; other site
1123863000784	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1123863000785	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863000786	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1123863000787	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1123863000788	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863000789	hypothetical protein; Provisional; Region: PRK11056
1123863000790	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1123863000791	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863000792	S-adenosylmethionine binding site [chemical binding]; other site
1123863000793	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1123863000794	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863000795	N-terminal plug; other site
1123863000796	ligand-binding site [chemical binding]; other site
1123863000797	glutamate racemase; Provisional; Region: PRK00865
1123863000798	transcriptional regulator HdfR; Provisional; Region: PRK03601
1123863000799	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863000800	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1123863000801	dimerization interface [polypeptide binding]; other site
1123863000802	hypothetical protein; Provisional; Region: PRK11027
1123863000803	putative ATP-dependent protease; Provisional; Region: PRK09862
1123863000804	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1123863000805	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863000806	Walker A motif; other site
1123863000807	ATP binding site [chemical binding]; other site
1123863000808	Walker B motif; other site
1123863000809	arginine finger; other site
1123863000810	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1123863000811	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1123863000812	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1123863000813	PYR/PP interface [polypeptide binding]; other site
1123863000814	dimer interface [polypeptide binding]; other site
1123863000815	TPP binding site [chemical binding]; other site
1123863000816	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1123863000817	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1123863000818	TPP-binding site [chemical binding]; other site
1123863000819	dimer interface [polypeptide binding]; other site
1123863000820	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1123863000821	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1123863000822	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1123863000823	homodimer interface [polypeptide binding]; other site
1123863000824	substrate-cofactor binding pocket; other site
1123863000825	catalytic residue [active]
1123863000826	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1123863000827	threonine dehydratase; Reviewed; Region: PRK09224
1123863000828	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1123863000829	tetramer interface [polypeptide binding]; other site
1123863000830	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863000831	catalytic residue [active]
1123863000832	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1123863000833	putative Ile/Val binding site [chemical binding]; other site
1123863000834	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1123863000835	putative Ile/Val binding site [chemical binding]; other site
1123863000836	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863000837	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1123863000838	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1123863000839	putative dimerization interface [polypeptide binding]; other site
1123863000840	ketol-acid reductoisomerase; Validated; Region: PRK05225
1123863000841	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1123863000842	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1123863000843	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1123863000844	H+ Antiporter protein; Region: 2A0121; TIGR00900
1123863000845	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000846	putative substrate translocation pore; other site
1123863000847	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1123863000848	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1123863000849	classical (c) SDRs; Region: SDR_c; cd05233
1123863000850	NAD(P) binding site [chemical binding]; other site
1123863000851	active site
1123863000852	Biofilm formation and stress response factor; Region: BsmA; pfam10014
1123863000853	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1123863000854	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863000855	substrate binding pocket [chemical binding]; other site
1123863000856	membrane-bound complex binding site; other site
1123863000857	hinge residues; other site
1123863000858	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863000859	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863000860	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1123863000861	putative effector binding pocket; other site
1123863000862	dimerization interface [polypeptide binding]; other site
1123863000863	metabolite-proton symporter; Region: 2A0106; TIGR00883
1123863000864	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000865	putative substrate translocation pore; other site
1123863000866	inner membrane protein YhjD; Region: TIGR00766
1123863000867	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863000868	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863000869	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1123863000870	putative effector binding pocket; other site
1123863000871	putative dimerization interface [polypeptide binding]; other site
1123863000872	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1123863000873	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863000874	NAD(P) binding site [chemical binding]; other site
1123863000875	active site
1123863000876	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1123863000877	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
1123863000878	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1123863000879	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1123863000880	putative C-terminal domain interface [polypeptide binding]; other site
1123863000881	putative GSH binding site (G-site) [chemical binding]; other site
1123863000882	putative dimer interface [polypeptide binding]; other site
1123863000883	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1123863000884	putative N-terminal domain interface [polypeptide binding]; other site
1123863000885	putative dimer interface [polypeptide binding]; other site
1123863000886	putative substrate binding pocket (H-site) [chemical binding]; other site
1123863000887	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1123863000888	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863000889	DNA-binding site [nucleotide binding]; DNA binding site
1123863000890	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863000891	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863000892	homodimer interface [polypeptide binding]; other site
1123863000893	catalytic residue [active]
1123863000894	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1123863000895	malate:quinone oxidoreductase; Validated; Region: PRK05257
1123863000896	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1123863000897	hypothetical protein; Provisional; Region: PRK11469
1123863000898	Domain of unknown function DUF; Region: DUF204; pfam02659
1123863000899	Domain of unknown function DUF; Region: DUF204; pfam02659
1123863000900	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1123863000901	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1123863000902	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1123863000903	TAP-like protein; Region: Abhydrolase_4; pfam08386
1123863000904	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000905	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863000906	putative substrate translocation pore; other site
1123863000907	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863000908	DNA-binding site [nucleotide binding]; DNA binding site
1123863000909	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1123863000910	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1123863000911	FCD domain; Region: FCD; pfam07729
1123863000912	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1123863000913	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1123863000914	putative NAD(P) binding site [chemical binding]; other site
1123863000915	catalytic Zn binding site [ion binding]; other site
1123863000916	structural Zn binding site [ion binding]; other site
1123863000917	Inosine-uridine preferring nucleoside hydrolase; Region: IU_nuc_hydro; pfam01156
1123863000918	active site
1123863000919	chromosome condensation membrane protein; Provisional; Region: PRK14196
1123863000920	putative hydrolase; Provisional; Region: PRK11460
1123863000921	Predicted esterase [General function prediction only]; Region: COG0400
1123863000922	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
1123863000923	Protein of unknown function, DUF482; Region: DUF482; pfam04339
1123863000924	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1123863000925	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1123863000926	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863000927	Walker A/P-loop; other site
1123863000928	ATP binding site [chemical binding]; other site
1123863000929	Q-loop/lid; other site
1123863000930	ABC transporter signature motif; other site
1123863000931	Walker B; other site
1123863000932	D-loop; other site
1123863000933	H-loop/switch region; other site
1123863000934	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1123863000935	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863000936	Coenzyme A binding pocket [chemical binding]; other site
1123863000937	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1123863000938	Domain of unknown function (DUF3391); Region: DUF3391; pfam11871
1123863000939	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1123863000940	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1123863000941	Zn2+ binding site [ion binding]; other site
1123863000942	Mg2+ binding site [ion binding]; other site
1123863000943	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1123863000944	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1123863000945	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1123863000946	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1123863000947	sensor protein KdpD; Provisional; Region: PRK10490
1123863000948	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1123863000949	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1123863000950	Ligand Binding Site [chemical binding]; other site
1123863000951	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1123863000952	GAF domain; Region: GAF_3; pfam13492
1123863000953	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863000954	dimer interface [polypeptide binding]; other site
1123863000955	phosphorylation site [posttranslational modification]
1123863000956	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863000957	ATP binding site [chemical binding]; other site
1123863000958	Mg2+ binding site [ion binding]; other site
1123863000959	G-X-G motif; other site
1123863000960	hypothetical protein; Provisional; Region: PRK05208
1123863000961	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863000962	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863000963	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1123863000964	putative effector binding pocket; other site
1123863000965	dimerization interface [polypeptide binding]; other site
1123863000966	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1123863000967	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863000968	putative substrate translocation pore; other site
1123863000969	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1123863000970	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1123863000971	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1123863000972	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1123863000973	nucleophilic elbow; other site
1123863000974	catalytic triad; other site
1123863000975	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1123863000976	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1123863000977	trimer interface [polypeptide binding]; other site
1123863000978	eyelet of channel; other site
1123863000979	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1123863000980	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1123863000981	putative active site [active]
1123863000982	catalytic site [active]
1123863000983	putative metal binding site [ion binding]; other site
1123863000984	hypothetical protein; Provisional; Region: PRK11622
1123863000985	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1123863000986	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1123863000987	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863000988	dimer interface [polypeptide binding]; other site
1123863000989	conserved gate region; other site
1123863000990	putative PBP binding loops; other site
1123863000991	ABC-ATPase subunit interface; other site
1123863000992	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863000993	conserved gate region; other site
1123863000994	ABC-ATPase subunit interface; other site
1123863000995	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1123863000996	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863000997	Walker A/P-loop; other site
1123863000998	ATP binding site [chemical binding]; other site
1123863000999	Q-loop/lid; other site
1123863001000	ABC transporter signature motif; other site
1123863001001	Walker B; other site
1123863001002	D-loop; other site
1123863001003	H-loop/switch region; other site
1123863001004	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1123863001005	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1123863001006	active site
1123863001007	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1123863001008	MarR family; Region: MarR_2; pfam12802
1123863001009	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1123863001010	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1123863001011	glutathione reductase; Validated; Region: PRK06116
1123863001012	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863001013	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863001014	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1123863001015	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1123863001016	CAAX protease self-immunity; Region: Abi; pfam02517
1123863001017	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1123863001018	oligopeptidase A; Provisional; Region: PRK10911
1123863001019	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1123863001020	active site
1123863001021	Zn binding site [ion binding]; other site
1123863001022	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863001023	S-adenosylmethionine binding site [chemical binding]; other site
1123863001024	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1123863001025	Ligand Binding Site [chemical binding]; other site
1123863001026	universal stress protein UspB; Provisional; Region: PRK04960
1123863001027	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1123863001028	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1123863001029	Predicted flavoproteins [General function prediction only]; Region: COG2081
1123863001030	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863001031	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1123863001032	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1123863001033	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1123863001034	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1123863001035	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863001036	ABC transporter signature motif; other site
1123863001037	Walker B; other site
1123863001038	D-loop; other site
1123863001039	H-loop/switch region; other site
1123863001040	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1123863001041	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1123863001042	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863001043	Walker A/P-loop; other site
1123863001044	ATP binding site [chemical binding]; other site
1123863001045	Q-loop/lid; other site
1123863001046	ABC transporter signature motif; other site
1123863001047	Walker B; other site
1123863001048	D-loop; other site
1123863001049	H-loop/switch region; other site
1123863001050	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1123863001051	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
1123863001052	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1123863001053	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863001054	dimer interface [polypeptide binding]; other site
1123863001055	conserved gate region; other site
1123863001056	putative PBP binding loops; other site
1123863001057	ABC-ATPase subunit interface; other site
1123863001058	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1123863001059	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863001060	dimer interface [polypeptide binding]; other site
1123863001061	conserved gate region; other site
1123863001062	putative PBP binding loops; other site
1123863001063	ABC-ATPase subunit interface; other site
1123863001064	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1123863001065	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1123863001066	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
1123863001067	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1123863001068	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863001069	Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) [Translation, ribosomal structure and biogenesis]; Region: GatE; COG2511
1123863001070	short chain dehydrogenase; Provisional; Region: PRK08177
1123863001071	C factor cell-cell signaling protein; Provisional; Region: PRK09009
1123863001072	NAD(P) binding site [chemical binding]; other site
1123863001073	active site
1123863001074	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1123863001075	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1123863001076	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863001077	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863001078	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1123863001079	dimer interface [polypeptide binding]; other site
1123863001080	active site
1123863001081	Schiff base residues; other site
1123863001082	proline/glycine betaine transporter; Provisional; Region: PRK10642
1123863001083	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863001084	putative substrate translocation pore; other site
1123863001085	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1123863001086	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1123863001087	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863001088	mannonate dehydratase; Region: uxuA; TIGR00695
1123863001089	mannonate dehydratase; Provisional; Region: PRK03906
1123863001090	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1123863001091	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863001092	DNA-binding site [nucleotide binding]; DNA binding site
1123863001093	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1123863001094	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1123863001095	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1123863001096	xanthine permease; Region: pbuX; TIGR03173
1123863001097	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1123863001098	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1123863001099	tetrameric interface [polypeptide binding]; other site
1123863001100	NAD binding site [chemical binding]; other site
1123863001101	catalytic residues [active]
1123863001102	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1123863001103	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1123863001104	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863001105	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1123863001106	putative active site [active]
1123863001107	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1123863001108	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1123863001109	Metal-binding active site; metal-binding site
1123863001110	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
1123863001111	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1123863001112	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863001113	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1123863001114	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1123863001115	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1123863001116	PYR/PP interface [polypeptide binding]; other site
1123863001117	dimer interface [polypeptide binding]; other site
1123863001118	TPP binding site [chemical binding]; other site
1123863001119	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1123863001120	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1123863001121	TPP-binding site; other site
1123863001122	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863001123	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1123863001124	substrate binding site [chemical binding]; other site
1123863001125	ATP binding site [chemical binding]; other site
1123863001126	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
1123863001127	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
1123863001128	hypothetical protein; Provisional; Region: PRK11615
1123863001129	hypothetical protein; Provisional; Region: PRK11212
1123863001130	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1123863001131	CPxP  motif; other site
1123863001132	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1123863001133	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1123863001134	metal-binding site [ion binding]
1123863001135	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1123863001136	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1123863001137	Predicted membrane protein [Function unknown]; Region: COG3714
1123863001138	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1123863001139	hypothetical protein; Provisional; Region: PRK10910
1123863001140	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1123863001141	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863001142	S-adenosylmethionine binding site [chemical binding]; other site
1123863001143	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1123863001144	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1123863001145	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1123863001146	P loop; other site
1123863001147	GTP binding site [chemical binding]; other site
1123863001148	cell division protein FtsE; Provisional; Region: PRK10908
1123863001149	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863001150	Walker A/P-loop; other site
1123863001151	ATP binding site [chemical binding]; other site
1123863001152	Q-loop/lid; other site
1123863001153	ABC transporter signature motif; other site
1123863001154	Walker B; other site
1123863001155	D-loop; other site
1123863001156	H-loop/switch region; other site
1123863001157	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1123863001158	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1123863001159	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1123863001160	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863001161	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1123863001162	DNA binding residues [nucleotide binding]
1123863001163	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1123863001164	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1123863001165	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1123863001166	dimerization interface [polypeptide binding]; other site
1123863001167	ligand binding site [chemical binding]; other site
1123863001168	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863001169	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1123863001170	TM-ABC transporter signature motif; other site
1123863001171	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1123863001172	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1123863001173	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1123863001174	TM-ABC transporter signature motif; other site
1123863001175	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1123863001176	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1123863001177	Walker A/P-loop; other site
1123863001178	ATP binding site [chemical binding]; other site
1123863001179	Q-loop/lid; other site
1123863001180	ABC transporter signature motif; other site
1123863001181	Walker B; other site
1123863001182	D-loop; other site
1123863001183	H-loop/switch region; other site
1123863001184	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1123863001185	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1123863001186	Walker A/P-loop; other site
1123863001187	ATP binding site [chemical binding]; other site
1123863001188	Q-loop/lid; other site
1123863001189	ABC transporter signature motif; other site
1123863001190	Walker B; other site
1123863001191	D-loop; other site
1123863001192	H-loop/switch region; other site
1123863001193	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1123863001194	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1123863001195	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863001196	dimer interface [polypeptide binding]; other site
1123863001197	conserved gate region; other site
1123863001198	putative PBP binding loops; other site
1123863001199	ABC-ATPase subunit interface; other site
1123863001200	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1123863001201	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863001202	dimer interface [polypeptide binding]; other site
1123863001203	conserved gate region; other site
1123863001204	putative PBP binding loops; other site
1123863001205	ABC-ATPase subunit interface; other site
1123863001206	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1123863001207	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1123863001208	Walker A/P-loop; other site
1123863001209	ATP binding site [chemical binding]; other site
1123863001210	Q-loop/lid; other site
1123863001211	ABC transporter signature motif; other site
1123863001212	Walker B; other site
1123863001213	D-loop; other site
1123863001214	H-loop/switch region; other site
1123863001215	TOBE domain; Region: TOBE_2; pfam08402
1123863001216	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1123863001217	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1123863001218	putative active site [active]
1123863001219	catalytic site [active]
1123863001220	putative metal binding site [ion binding]; other site
1123863001221	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1123863001222	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1123863001223	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1123863001224	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863001225	Coenzyme A binding pocket [chemical binding]; other site
1123863001226	Pirin-related protein [General function prediction only]; Region: COG1741
1123863001227	Pirin; Region: Pirin; pfam02678
1123863001228	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1123863001229	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863001230	DNA binding site [nucleotide binding]
1123863001231	domain linker motif; other site
1123863001232	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1123863001233	putative ligand binding site [chemical binding]; other site
1123863001234	putative dimerization interface [polypeptide binding]; other site
1123863001235	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1123863001236	ATP-binding site [chemical binding]; other site
1123863001237	Gluconate-6-phosphate binding site [chemical binding]; other site
1123863001238	Shikimate kinase; Region: SKI; pfam01202
1123863001239	low affinity gluconate transporter; Provisional; Region: PRK10472
1123863001240	gluconate transporter; Region: gntP; TIGR00791
1123863001241	putative antibiotic transporter; Provisional; Region: PRK10739
1123863001242	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1123863001243	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1123863001244	glycogen branching enzyme; Provisional; Region: PRK05402
1123863001245	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1123863001246	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1123863001247	active site
1123863001248	catalytic site [active]
1123863001249	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1123863001250	glycogen debranching enzyme; Provisional; Region: PRK03705
1123863001251	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1123863001252	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1123863001253	active site
1123863001254	catalytic site [active]
1123863001255	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1123863001256	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1123863001257	ligand binding site; other site
1123863001258	oligomer interface; other site
1123863001259	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1123863001260	dimer interface [polypeptide binding]; other site
1123863001261	N-terminal domain interface [polypeptide binding]; other site
1123863001262	sulfate 1 binding site; other site
1123863001263	glycogen synthase; Provisional; Region: glgA; PRK00654
1123863001264	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1123863001265	ADP-binding pocket [chemical binding]; other site
1123863001266	homodimer interface [polypeptide binding]; other site
1123863001267	glycogen phosphorylase; Provisional; Region: PRK14986
1123863001268	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1123863001269	homodimer interface [polypeptide binding]; other site
1123863001270	active site pocket [active]
1123863001271	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1123863001272	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1123863001273	active site residue [active]
1123863001274	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1123863001275	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1123863001276	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1123863001277	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1123863001278	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1123863001279	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863001280	maltodextrin phosphorylase; Provisional; Region: PRK14985
1123863001281	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1123863001282	homodimer interface [polypeptide binding]; other site
1123863001283	active site pocket [active]
1123863001284	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1123863001285	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1123863001286	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1123863001287	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1123863001288	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1123863001289	DNA utilization protein GntX; Provisional; Region: PRK11595
1123863001290	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1123863001291	active site
1123863001292	carboxylesterase BioH; Provisional; Region: PRK10349
1123863001293	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1123863001294	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863001295	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1123863001296	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
1123863001297	active site
1123863001298	homodimer interface [polypeptide binding]; other site
1123863001299	catalytic site [active]
1123863001300	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1123863001301	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1123863001302	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1123863001303	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1123863001304	RNA binding site [nucleotide binding]; other site
1123863001305	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1123863001306	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1123863001307	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1123863001308	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1123863001309	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863001310	active site
1123863001311	phosphorylation site [posttranslational modification]
1123863001312	intermolecular recognition site; other site
1123863001313	dimerization interface [polypeptide binding]; other site
1123863001314	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863001315	DNA binding site [nucleotide binding]
1123863001316	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1123863001317	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863001318	dimerization interface [polypeptide binding]; other site
1123863001319	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863001320	dimer interface [polypeptide binding]; other site
1123863001321	phosphorylation site [posttranslational modification]
1123863001322	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863001323	ATP binding site [chemical binding]; other site
1123863001324	Mg2+ binding site [ion binding]; other site
1123863001325	G-X-G motif; other site
1123863001326	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1123863001327	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1123863001328	active site
1123863001329	substrate-binding site [chemical binding]; other site
1123863001330	metal-binding site [ion binding]
1123863001331	ATP binding site [chemical binding]; other site
1123863001332	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1123863001333	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1123863001334	dimerization interface [polypeptide binding]; other site
1123863001335	domain crossover interface; other site
1123863001336	redox-dependent activation switch; other site
1123863001337	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1123863001338	RNA binding surface [nucleotide binding]; other site
1123863001339	GMP/IMP nucleotidase; Provisional; Region: PRK14988
1123863001340	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1123863001341	motif II; other site
1123863001342	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1123863001343	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1123863001344	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1123863001345	ADP-ribose binding site [chemical binding]; other site
1123863001346	dimer interface [polypeptide binding]; other site
1123863001347	active site
1123863001348	nudix motif; other site
1123863001349	metal binding site [ion binding]; metal-binding site
1123863001350	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1123863001351	Transglycosylase; Region: Transgly; pfam00912
1123863001352	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1123863001353	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1123863001354	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1123863001355	putative outer membrane porin HofQ; Provisional; Region: hofQ; PRK13568
1123863001356	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1123863001357	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1123863001358	shikimate kinase; Reviewed; Region: aroK; PRK00131
1123863001359	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1123863001360	ADP binding site [chemical binding]; other site
1123863001361	magnesium binding site [ion binding]; other site
1123863001362	putative shikimate binding site; other site
1123863001363	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1123863001364	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
1123863001365	active site
1123863001366	dimer interface [polypeptide binding]; other site
1123863001367	metal binding site [ion binding]; metal-binding site
1123863001368	hypothetical protein; Reviewed; Region: PRK11901
1123863001369	cell division protein DamX; Validated; Region: PRK10905
1123863001370	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1123863001371	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1123863001372	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1123863001373	substrate binding site [chemical binding]; other site
1123863001374	hexamer interface [polypeptide binding]; other site
1123863001375	metal binding site [ion binding]; metal-binding site
1123863001376	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1123863001377	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1123863001378	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863001379	motif II; other site
1123863001380	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1123863001381	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1123863001382	active site
1123863001383	HIGH motif; other site
1123863001384	dimer interface [polypeptide binding]; other site
1123863001385	KMSKS motif; other site
1123863001386	cytosine deaminase; Provisional; Region: PRK09230
1123863001387	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1123863001388	active site
1123863001389	putative transporter; Provisional; Region: PRK03699
1123863001390	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863001391	putative substrate translocation pore; other site
1123863001392	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1123863001393	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1123863001394	substrate binding site [chemical binding]; other site
1123863001395	hypothetical protein; Provisional; Region: PRK10204
1123863001396	cell filamentation protein Fic; Provisional; Region: PRK10347
1123863001397	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1123863001398	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1123863001399	glutamine binding [chemical binding]; other site
1123863001400	catalytic triad [active]
1123863001401	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1123863001402	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863001403	inhibitor-cofactor binding pocket; inhibition site
1123863001404	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863001405	catalytic residue [active]
1123863001406	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1123863001407	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1123863001408	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1123863001409	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1123863001410	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1123863001411	ligand binding site [chemical binding]; other site
1123863001412	flexible hinge region; other site
1123863001413	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1123863001414	putative switch regulator; other site
1123863001415	non-specific DNA interactions [nucleotide binding]; other site
1123863001416	DNA binding site [nucleotide binding]
1123863001417	sequence specific DNA binding site [nucleotide binding]; other site
1123863001418	putative cAMP binding site [chemical binding]; other site
1123863001419	hypothetical protein; Provisional; Region: PRK10738
1123863001420	phosphoribulokinase; Provisional; Region: PRK15453
1123863001421	active site
1123863001422	hypothetical protein; Provisional; Region: PRK04966
1123863001423	putative hydrolase; Provisional; Region: PRK10985
1123863001424	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1123863001425	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863001426	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863001427	DNA binding site [nucleotide binding]
1123863001428	domain linker motif; other site
1123863001429	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1123863001430	dimerization interface [polypeptide binding]; other site
1123863001431	ligand binding site [chemical binding]; other site
1123863001432	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
1123863001433	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863001434	substrate binding pocket [chemical binding]; other site
1123863001435	membrane-bound complex binding site; other site
1123863001436	hinge residues; other site
1123863001437	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
1123863001438	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1123863001439	Walker A/P-loop; other site
1123863001440	ATP binding site [chemical binding]; other site
1123863001441	Q-loop/lid; other site
1123863001442	ABC transporter signature motif; other site
1123863001443	Walker B; other site
1123863001444	D-loop; other site
1123863001445	H-loop/switch region; other site
1123863001446	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1123863001447	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863001448	dimer interface [polypeptide binding]; other site
1123863001449	conserved gate region; other site
1123863001450	putative PBP binding loops; other site
1123863001451	ABC-ATPase subunit interface; other site
1123863001452	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
1123863001453	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
1123863001454	active site
1123863001455	iron coordination sites [ion binding]; other site
1123863001456	substrate binding pocket [chemical binding]; other site
1123863001457	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1123863001458	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863001459	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863001460	ABC transporter; Region: ABC_tran_2; pfam12848
1123863001461	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863001462	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1123863001463	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1123863001464	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1123863001465	TrkA-N domain; Region: TrkA_N; pfam02254
1123863001466	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1123863001467	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
1123863001468	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1123863001469	phi X174 lysis protein; Provisional; Region: PRK02793
1123863001470	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1123863001471	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1123863001472	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1123863001473	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1123863001474	YheO-like PAS domain; Region: PAS_6; pfam08348
1123863001475	HTH domain; Region: HTH_22; pfam13309
1123863001476	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1123863001477	sulfur relay protein TusC; Validated; Region: PRK00211
1123863001478	DsrH like protein; Region: DsrH; cl17347
1123863001479	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1123863001480	S17 interaction site [polypeptide binding]; other site
1123863001481	S8 interaction site; other site
1123863001482	16S rRNA interaction site [nucleotide binding]; other site
1123863001483	streptomycin interaction site [chemical binding]; other site
1123863001484	23S rRNA interaction site [nucleotide binding]; other site
1123863001485	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1123863001486	30S ribosomal protein S7; Validated; Region: PRK05302
1123863001487	elongation factor G; Reviewed; Region: PRK00007
1123863001488	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1123863001489	G1 box; other site
1123863001490	putative GEF interaction site [polypeptide binding]; other site
1123863001491	GTP/Mg2+ binding site [chemical binding]; other site
1123863001492	Switch I region; other site
1123863001493	G2 box; other site
1123863001494	G3 box; other site
1123863001495	Switch II region; other site
1123863001496	G4 box; other site
1123863001497	G5 box; other site
1123863001498	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1123863001499	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1123863001500	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1123863001501	elongation factor Tu; Reviewed; Region: PRK00049
1123863001502	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1123863001503	G1 box; other site
1123863001504	GEF interaction site [polypeptide binding]; other site
1123863001505	GTP/Mg2+ binding site [chemical binding]; other site
1123863001506	Switch I region; other site
1123863001507	G2 box; other site
1123863001508	G3 box; other site
1123863001509	Switch II region; other site
1123863001510	G4 box; other site
1123863001511	G5 box; other site
1123863001512	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1123863001513	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1123863001514	Antibiotic Binding Site [chemical binding]; other site
1123863001515	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1123863001516	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1123863001517	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1123863001518	heme binding site [chemical binding]; other site
1123863001519	ferroxidase pore; other site
1123863001520	ferroxidase diiron center [ion binding]; other site
1123863001521	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1123863001522	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1123863001523	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1123863001524	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1123863001525	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1123863001526	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1123863001527	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1123863001528	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1123863001529	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1123863001530	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1123863001531	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1123863001532	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1123863001533	protein-rRNA interface [nucleotide binding]; other site
1123863001534	putative translocon binding site; other site
1123863001535	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1123863001536	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1123863001537	G-X-X-G motif; other site
1123863001538	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1123863001539	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1123863001540	23S rRNA interface [nucleotide binding]; other site
1123863001541	5S rRNA interface [nucleotide binding]; other site
1123863001542	putative antibiotic binding site [chemical binding]; other site
1123863001543	L25 interface [polypeptide binding]; other site
1123863001544	L27 interface [polypeptide binding]; other site
1123863001545	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1123863001546	23S rRNA interface [nucleotide binding]; other site
1123863001547	putative translocon interaction site; other site
1123863001548	signal recognition particle (SRP54) interaction site; other site
1123863001549	L23 interface [polypeptide binding]; other site
1123863001550	trigger factor interaction site; other site
1123863001551	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1123863001552	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1123863001553	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1123863001554	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1123863001555	RNA binding site [nucleotide binding]; other site
1123863001556	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1123863001557	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1123863001558	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1123863001559	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1123863001560	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1123863001561	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1123863001562	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1123863001563	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1123863001564	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1123863001565	23S rRNA interface [nucleotide binding]; other site
1123863001566	5S rRNA interface [nucleotide binding]; other site
1123863001567	L27 interface [polypeptide binding]; other site
1123863001568	L5 interface [polypeptide binding]; other site
1123863001569	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1123863001570	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1123863001571	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1123863001572	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1123863001573	23S rRNA binding site [nucleotide binding]; other site
1123863001574	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1123863001575	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1123863001576	SecY translocase; Region: SecY; pfam00344
1123863001577	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1123863001578	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1123863001579	30S ribosomal protein S11; Validated; Region: PRK05309
1123863001580	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1123863001581	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1123863001582	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1123863001583	RNA binding surface [nucleotide binding]; other site
1123863001584	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1123863001585	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1123863001586	alphaNTD homodimer interface [polypeptide binding]; other site
1123863001587	alphaNTD - beta interaction site [polypeptide binding]; other site
1123863001588	alphaNTD - beta' interaction site [polypeptide binding]; other site
1123863001589	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1123863001590	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1123863001591	Domain of unknown function (DUF1992); Region: DUF1992; cl08096
1123863001592	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1123863001593	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1123863001594	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1123863001595	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1123863001596	TrkA-N domain; Region: TrkA_N; pfam02254
1123863001597	TrkA-C domain; Region: TrkA_C; pfam02080
1123863001598	TrkA-N domain; Region: TrkA_N; pfam02254
1123863001599	TrkA-C domain; Region: TrkA_C; pfam02080
1123863001600	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1123863001601	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1123863001602	putative RNA binding site [nucleotide binding]; other site
1123863001603	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863001604	S-adenosylmethionine binding site [chemical binding]; other site
1123863001605	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1123863001606	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1123863001607	putative active site [active]
1123863001608	substrate binding site [chemical binding]; other site
1123863001609	putative cosubstrate binding site; other site
1123863001610	catalytic site [active]
1123863001611	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1123863001612	substrate binding site [chemical binding]; other site
1123863001613	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1123863001614	active site
1123863001615	catalytic residues [active]
1123863001616	metal binding site [ion binding]; metal-binding site
1123863001617	hypothetical protein; Provisional; Region: PRK10736
1123863001618	DNA protecting protein DprA; Region: dprA; TIGR00732
1123863001619	hypothetical protein; Validated; Region: PRK03430
1123863001620	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1123863001621	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1123863001622	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1123863001623	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1123863001624	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1123863001625	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1123863001626	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1123863001627	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1123863001628	shikimate binding site; other site
1123863001629	NAD(P) binding site [chemical binding]; other site
1123863001630	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1123863001631	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1123863001632	trimer interface [polypeptide binding]; other site
1123863001633	putative metal binding site [ion binding]; other site
1123863001634	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1123863001635	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863001636	Walker A/P-loop; other site
1123863001637	ATP binding site [chemical binding]; other site
1123863001638	Q-loop/lid; other site
1123863001639	ABC transporter signature motif; other site
1123863001640	Walker B; other site
1123863001641	D-loop; other site
1123863001642	H-loop/switch region; other site
1123863001643	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863001644	dimer interface [polypeptide binding]; other site
1123863001645	conserved gate region; other site
1123863001646	putative PBP binding loops; other site
1123863001647	ABC-ATPase subunit interface; other site
1123863001648	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
1123863001649	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863001650	conserved gate region; other site
1123863001651	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863001652	ABC-ATPase subunit interface; other site
1123863001653	putative PBP binding loops; other site
1123863001654	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863001655	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1123863001656	substrate binding pocket [chemical binding]; other site
1123863001657	membrane-bound complex binding site; other site
1123863001658	hinge residues; other site
1123863001659	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1123863001660	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1123863001661	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
1123863001662	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1123863001663	FMN binding site [chemical binding]; other site
1123863001664	active site
1123863001665	catalytic residues [active]
1123863001666	substrate binding site [chemical binding]; other site
1123863001667	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1123863001668	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1123863001669	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1123863001670	Na binding site [ion binding]; other site
1123863001671	hypothetical protein; Provisional; Region: PRK10633
1123863001672	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1123863001673	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1123863001674	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1123863001675	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1123863001676	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1123863001677	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1123863001678	carboxyltransferase (CT) interaction site; other site
1123863001679	biotinylation site [posttranslational modification]; other site
1123863001680	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1123863001681	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1123863001682	active site
1123863001683	trimer interface [polypeptide binding]; other site
1123863001684	dimer interface [polypeptide binding]; other site
1123863001685	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1123863001686	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1123863001687	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1123863001688	Moco binding site; other site
1123863001689	metal coordination site [ion binding]; other site
1123863001690	regulatory protein CsrD; Provisional; Region: PRK11059
1123863001691	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863001692	active site
1123863001693	I-site; other site
1123863001694	metal binding site [ion binding]; metal-binding site
1123863001695	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863001696	rod shape-determining protein MreB; Provisional; Region: PRK13927
1123863001697	MreB and similar proteins; Region: MreB_like; cd10225
1123863001698	nucleotide binding site [chemical binding]; other site
1123863001699	Mg binding site [ion binding]; other site
1123863001700	putative protofilament interaction site [polypeptide binding]; other site
1123863001701	RodZ interaction site [polypeptide binding]; other site
1123863001702	rod shape-determining protein MreC; Region: mreC; TIGR00219
1123863001703	rod shape-determining protein MreC; Region: MreC; pfam04085
1123863001704	rod shape-determining protein MreD; Provisional; Region: PRK11060
1123863001705	Maf-like protein; Region: Maf; pfam02545
1123863001706	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1123863001707	active site
1123863001708	dimer interface [polypeptide binding]; other site
1123863001709	ribonuclease G; Provisional; Region: PRK11712
1123863001710	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1123863001711	homodimer interface [polypeptide binding]; other site
1123863001712	oligonucleotide binding site [chemical binding]; other site
1123863001713	hypothetical protein; Provisional; Region: PRK10899
1123863001714	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1123863001715	protease TldD; Provisional; Region: tldD; PRK10735
1123863001716	transcriptional regulator; Provisional; Region: PRK10632
1123863001717	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863001718	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1123863001719	putative effector binding pocket; other site
1123863001720	dimerization interface [polypeptide binding]; other site
1123863001721	efflux system membrane protein; Provisional; Region: PRK11594
1123863001722	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1123863001723	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863001724	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863001725	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1123863001726	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1123863001727	succinic semialdehyde dehydrogenase; Region: PLN02278
1123863001728	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1123863001729	tetramerization interface [polypeptide binding]; other site
1123863001730	NAD(P) binding site [chemical binding]; other site
1123863001731	catalytic residues [active]
1123863001732	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it, thus inhibiting its potentially lethal RNase activity inside the...; Region: Barstar_like; cl01048
1123863001733	RNAase interaction site [polypeptide binding]; other site
1123863001734	potential frameshift: common BLAST hit: gi|305696886|ref|YP_003864201.1| putative transposase
1123863001735	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1123863001736	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1123863001737	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863001738	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863001739	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863001740	arginine repressor; Provisional; Region: PRK05066
1123863001741	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1123863001742	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1123863001743	malate dehydrogenase; Provisional; Region: PRK05086
1123863001744	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1123863001745	NAD binding site [chemical binding]; other site
1123863001746	dimerization interface [polypeptide binding]; other site
1123863001747	Substrate binding site [chemical binding]; other site
1123863001748	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1123863001749	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1123863001750	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1123863001751	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1123863001752	GTPase RsgA; Reviewed; Region: PRK12288
1123863001753	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1123863001754	RNA binding site [nucleotide binding]; other site
1123863001755	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1123863001756	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1123863001757	GTP/Mg2+ binding site [chemical binding]; other site
1123863001758	G4 box; other site
1123863001759	G5 box; other site
1123863001760	G1 box; other site
1123863001761	Switch I region; other site
1123863001762	G2 box; other site
1123863001763	G3 box; other site
1123863001764	Switch II region; other site
1123863001765	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1123863001766	catalytic site [active]
1123863001767	putative active site [active]
1123863001768	putative substrate binding site [chemical binding]; other site
1123863001769	dimer interface [polypeptide binding]; other site
1123863001770	epoxyqueuosine reductase; Region: TIGR00276
1123863001771	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1123863001772	putative carbohydrate kinase; Provisional; Region: PRK10565
1123863001773	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1123863001774	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1123863001775	putative substrate binding site [chemical binding]; other site
1123863001776	putative ATP binding site [chemical binding]; other site
1123863001777	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
1123863001778	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1123863001779	AMIN domain; Region: AMIN; pfam11741
1123863001780	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1123863001781	active site
1123863001782	metal binding site [ion binding]; metal-binding site
1123863001783	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1123863001784	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1123863001785	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1123863001786	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1123863001787	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863001788	ATP binding site [chemical binding]; other site
1123863001789	Mg2+ binding site [ion binding]; other site
1123863001790	G-X-G motif; other site
1123863001791	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1123863001792	ATP binding site [chemical binding]; other site
1123863001793	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1123863001794	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1123863001795	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1123863001796	bacterial Hfq-like; Region: Hfq; cd01716
1123863001797	hexamer interface [polypeptide binding]; other site
1123863001798	Sm1 motif; other site
1123863001799	RNA binding site [nucleotide binding]; other site
1123863001800	Sm2 motif; other site
1123863001801	GTPase HflX; Provisional; Region: PRK11058
1123863001802	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1123863001803	HflX GTPase family; Region: HflX; cd01878
1123863001804	G1 box; other site
1123863001805	GTP/Mg2+ binding site [chemical binding]; other site
1123863001806	Switch I region; other site
1123863001807	G2 box; other site
1123863001808	G3 box; other site
1123863001809	Switch II region; other site
1123863001810	G4 box; other site
1123863001811	G5 box; other site
1123863001812	FtsH protease regulator HflK; Provisional; Region: PRK10930
1123863001813	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1123863001814	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1123863001815	FtsH protease regulator HflC; Provisional; Region: PRK11029
1123863001816	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1123863001817	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1123863001818	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1123863001819	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1123863001820	GDP-binding site [chemical binding]; other site
1123863001821	ACT binding site; other site
1123863001822	IMP binding site; other site
1123863001823	transcriptional repressor NsrR; Provisional; Region: PRK11014
1123863001824	Rrf2 family protein; Region: rrf2_super; TIGR00738
1123863001825	exoribonuclease R; Provisional; Region: PRK11642
1123863001826	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1123863001827	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1123863001828	RNB domain; Region: RNB; pfam00773
1123863001829	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1123863001830	RNA binding site [nucleotide binding]; other site
1123863001831	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1123863001832	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1123863001833	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1123863001834	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1123863001835	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1123863001836	active site
1123863001837	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1123863001838	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863001839	dimerization interface [polypeptide binding]; other site
1123863001840	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863001841	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863001842	dimer interface [polypeptide binding]; other site
1123863001843	putative CheW interface [polypeptide binding]; other site
1123863001844	esterase; Provisional; Region: PRK10566
1123863001845	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1123863001846	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1123863001847	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1123863001848	dimer interface [polypeptide binding]; other site
1123863001849	ssDNA binding site [nucleotide binding]; other site
1123863001850	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1123863001851	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1123863001852	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1123863001853	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1123863001854	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1123863001855	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863001856	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1123863001857	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1123863001858	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1123863001859	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1123863001860	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1123863001861	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1123863001862	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1123863001863	active site
1123863001864	metal binding site [ion binding]; metal-binding site
1123863001865	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1123863001866	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1123863001867	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1123863001868	active site
1123863001869	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
1123863001870	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1123863001871	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1123863001872	Domain of unknown function DUF21; Region: DUF21; pfam01595
1123863001873	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1123863001874	Transporter associated domain; Region: CorC_HlyC; smart01091
1123863001875	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1123863001876	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1123863001877	Surface antigen; Region: Bac_surface_Ag; pfam01103
1123863001878	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1123863001879	Family of unknown function (DUF490); Region: DUF490; pfam04357
1123863001880	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1123863001881	putative active site pocket [active]
1123863001882	dimerization interface [polypeptide binding]; other site
1123863001883	putative catalytic residue [active]
1123863001884	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1123863001885	dimer interface [polypeptide binding]; other site
1123863001886	substrate binding site [chemical binding]; other site
1123863001887	metal binding sites [ion binding]; metal-binding site
1123863001888	Predicted membrane protein [Function unknown]; Region: COG2707
1123863001889	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1123863001890	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1123863001891	dimer interface [polypeptide binding]; other site
1123863001892	ligand binding site [chemical binding]; other site
1123863001893	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863001894	dimerization interface [polypeptide binding]; other site
1123863001895	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863001896	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863001897	dimer interface [polypeptide binding]; other site
1123863001898	putative CheW interface [polypeptide binding]; other site
1123863001899	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1123863001900	AMP binding site [chemical binding]; other site
1123863001901	metal binding site [ion binding]; metal-binding site
1123863001902	active site
1123863001903	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1123863001904	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1123863001905	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1123863001906	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1123863001907	hypothetical protein; Provisional; Region: PRK05255
1123863001908	peptidase PmbA; Provisional; Region: PRK11040
1123863001909	Cytochrome b562; Region: Cytochrom_B562; cl01546
1123863001910	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1123863001911	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863001912	putative DNA binding site [nucleotide binding]; other site
1123863001913	putative Zn2+ binding site [ion binding]; other site
1123863001914	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863001915	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863001916	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1123863001917	substrate binding site [chemical binding]; other site
1123863001918	ATP binding site [chemical binding]; other site
1123863001919	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1123863001920	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1123863001921	Class I aldolases; Region: Aldolase_Class_I; cl17187
1123863001922	catalytic residue [active]
1123863001923	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1123863001924	dimerization interface [polypeptide binding]; other site
1123863001925	putative active cleft [active]
1123863001926	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
1123863001927	active site
1123863001928	catalytic residues [active]
1123863001929	alpha-glucosidase; Provisional; Region: PRK10426
1123863001930	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1123863001931	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1123863001932	putative active site [active]
1123863001933	putative catalytic site [active]
1123863001934	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1123863001935	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1123863001936	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863001937	putative substrate translocation pore; other site
1123863001938	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1123863001939	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1123863001940	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1123863001941	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; pfam14272
1123863001942	Domain of unknown function (DUF4312); Region: DUF4312; pfam14189
1123863001943	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1123863001944	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1123863001945	dihydroorotase; Provisional; Region: PRK09237
1123863001946	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1123863001947	active site
1123863001948	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1123863001949	catalytic residue [active]
1123863001950	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1123863001951	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1123863001952	HTH domain; Region: HTH_11; pfam08279
1123863001953	Mga helix-turn-helix domain; Region: Mga; pfam05043
1123863001954	PRD domain; Region: PRD; pfam00874
1123863001955	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1123863001956	active site
1123863001957	P-loop; other site
1123863001958	phosphorylation site [posttranslational modification]
1123863001959	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863001960	active site
1123863001961	phosphorylation site [posttranslational modification]
1123863001962	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863001963	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1123863001964	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863001965	dimerization interface [polypeptide binding]; other site
1123863001966	Pirin-related protein [General function prediction only]; Region: COG1741
1123863001967	Pirin; Region: Pirin; pfam02678
1123863001968	outer membrane lipoprotein; Provisional; Region: PRK11023
1123863001969	BON domain; Region: BON; pfam04972
1123863001970	BON domain; Region: BON; pfam04972
1123863001971	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1123863001972	dimer interface [polypeptide binding]; other site
1123863001973	active site
1123863001974	hypothetical protein; Reviewed; Region: PRK12497
1123863001975	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1123863001976	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1123863001977	putative ligand binding site [chemical binding]; other site
1123863001978	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1123863001979	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1123863001980	putative SAM binding site [chemical binding]; other site
1123863001981	putative homodimer interface [polypeptide binding]; other site
1123863001982	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1123863001983	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1123863001984	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1123863001985	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1123863001986	tetramer interface [polypeptide binding]; other site
1123863001987	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863001988	catalytic residue [active]
1123863001989	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1123863001990	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1123863001991	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1123863001992	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1123863001993	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1123863001994	putative dimer interface [polypeptide binding]; other site
1123863001995	N-terminal domain interface [polypeptide binding]; other site
1123863001996	putative substrate binding pocket (H-site) [chemical binding]; other site
1123863001997	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
1123863001998	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1123863001999	active site
1123863002000	substrate binding site [chemical binding]; other site
1123863002001	cosubstrate binding site; other site
1123863002002	catalytic site [active]
1123863002003	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1123863002004	active site
1123863002005	hexamer interface [polypeptide binding]; other site
1123863002006	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
1123863002007	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033
1123863002008	Predicted membrane protein [Function unknown]; Region: COG2259
1123863002009	YqjK-like protein; Region: YqjK; pfam13997
1123863002010	Predicted membrane protein [Function unknown]; Region: COG5393
1123863002011	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1123863002012	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1123863002013	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1123863002014	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1123863002015	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1123863002016	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
1123863002017	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863002018	DNA-binding site [nucleotide binding]; DNA binding site
1123863002019	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1123863002020	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863002021	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002022	putative substrate translocation pore; other site
1123863002023	Glucuronate isomerase; Region: UxaC; pfam02614
1123863002024	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1123863002025	altronate oxidoreductase; Provisional; Region: PRK03643
1123863002026	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1123863002027	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1123863002028	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1123863002029	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1123863002030	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1123863002031	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1123863002032	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1123863002033	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863002034	putative voltage-gated ClC-type chloride channel ClcB; Provisional; Region: PRK01862
1123863002035	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1123863002036	Cl- selectivity filter; other site
1123863002037	Cl- binding residues [ion binding]; other site
1123863002038	pore gating glutamate residue; other site
1123863002039	dimer interface [polypeptide binding]; other site
1123863002040	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1123863002041	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1123863002042	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1123863002043	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863002044	S-adenosylmethionine binding site [chemical binding]; other site
1123863002045	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1123863002046	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1123863002047	active site
1123863002048	FMN binding site [chemical binding]; other site
1123863002049	2,4-decadienoyl-CoA binding site; other site
1123863002050	catalytic residue [active]
1123863002051	4Fe-4S cluster binding site [ion binding]; other site
1123863002052	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1123863002053	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863002054	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1123863002055	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863002056	active site
1123863002057	motif I; other site
1123863002058	motif II; other site
1123863002059	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1123863002060	active site clefts [active]
1123863002061	zinc binding site [ion binding]; other site
1123863002062	dimer interface [polypeptide binding]; other site
1123863002063	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1123863002064	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1123863002065	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1123863002066	MASE1; Region: MASE1; cl17823
1123863002067	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863002068	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863002069	metal binding site [ion binding]; metal-binding site
1123863002070	active site
1123863002071	I-site; other site
1123863002072	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1123863002073	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1123863002074	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1123863002075	anti-RssB factor; Provisional; Region: PRK10244
1123863002076	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863002077	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863002078	metal binding site [ion binding]; metal-binding site
1123863002079	active site
1123863002080	I-site; other site
1123863002081	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1123863002082	GAF domain; Region: GAF; pfam01590
1123863002083	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863002084	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863002085	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1123863002086	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863002087	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863002088	dimer interface [polypeptide binding]; other site
1123863002089	putative CheW interface [polypeptide binding]; other site
1123863002090	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1123863002091	GAF domain; Region: GAF; pfam01590
1123863002092	PAS domain S-box; Region: sensory_box; TIGR00229
1123863002093	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863002094	putative active site [active]
1123863002095	heme pocket [chemical binding]; other site
1123863002096	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863002097	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863002098	metal binding site [ion binding]; metal-binding site
1123863002099	active site
1123863002100	I-site; other site
1123863002101	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863002102	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1123863002103	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1123863002104	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863002105	dimerization interface [polypeptide binding]; other site
1123863002106	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863002107	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863002108	dimer interface [polypeptide binding]; other site
1123863002109	putative CheW interface [polypeptide binding]; other site
1123863002110	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863002111	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863002112	dimer interface [polypeptide binding]; other site
1123863002113	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1123863002114	putative CheW interface [polypeptide binding]; other site
1123863002115	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1123863002116	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1123863002117	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1123863002118	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1123863002119	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1123863002120	HTH domain; Region: HTH_11; pfam08279
1123863002121	PRD domain; Region: PRD; pfam00874
1123863002122	PRD domain; Region: PRD; pfam00874
1123863002123	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1123863002124	active site
1123863002125	P-loop; other site
1123863002126	phosphorylation site [posttranslational modification]
1123863002127	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863002128	active site
1123863002129	phosphorylation site [posttranslational modification]
1123863002130	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1123863002131	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1123863002132	active site
1123863002133	P-loop; other site
1123863002134	phosphorylation site [posttranslational modification]
1123863002135	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
1123863002136	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1123863002137	intersubunit interface [polypeptide binding]; other site
1123863002138	active site
1123863002139	zinc binding site [ion binding]; other site
1123863002140	Na+ binding site [ion binding]; other site
1123863002141	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1123863002142	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1123863002143	DksA-like zinc finger domain containing protein; Region: PHA00080
1123863002144	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1123863002145	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1123863002146	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1123863002147	catalytic residues [active]
1123863002148	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1123863002149	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1123863002150	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1123863002151	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1123863002152	baseplate wedge subunit; Provisional; Region: W; PHA02516
1123863002153	baseplate assembly protein; Provisional; Region: J; PHA02568
1123863002154	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1123863002155	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1123863002156	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1123863002157	major tail sheath protein; Provisional; Region: FI; PHA02560
1123863002158	Phage tail tube protein FII; Region: Phage_tube; cl01390
1123863002159	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1123863002160	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1123863002161	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
1123863002162	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1123863002163	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1123863002164	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1123863002165	Thymidylate synthase complementing protein; Region: Thy1; cl03630
1123863002166	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1123863002167	dimer interface [polypeptide binding]; other site
1123863002168	active site
1123863002169	catalytic residues [active]
1123863002170	Int/Topo IB signature motif; other site
1123863002171	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1123863002172	active site
1123863002173	SUMO-1 interface [polypeptide binding]; other site
1123863002174	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1123863002175	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1123863002176	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1123863002177	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1123863002178	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863002179	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1123863002180	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1123863002181	DNA binding residues [nucleotide binding]
1123863002182	DNA primase; Validated; Region: dnaG; PRK05667
1123863002183	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1123863002184	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1123863002185	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1123863002186	active site
1123863002187	metal binding site [ion binding]; metal-binding site
1123863002188	interdomain interaction site; other site
1123863002189	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1123863002190	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1123863002191	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1123863002192	UGMP family protein; Validated; Region: PRK09604
1123863002193	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1123863002194	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1123863002195	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1123863002196	homooctamer interface [polypeptide binding]; other site
1123863002197	active site
1123863002198	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1123863002199	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1123863002200	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1123863002201	active site
1123863002202	NTP binding site [chemical binding]; other site
1123863002203	metal binding triad [ion binding]; metal-binding site
1123863002204	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1123863002205	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1123863002206	Zn2+ binding site [ion binding]; other site
1123863002207	Mg2+ binding site [ion binding]; other site
1123863002208	SH3 domain-containing protein; Provisional; Region: PRK10884
1123863002209	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1123863002210	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1123863002211	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1123863002212	putative active site [active]
1123863002213	putative metal binding residues [ion binding]; other site
1123863002214	signature motif; other site
1123863002215	putative triphosphate binding site [ion binding]; other site
1123863002216	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1123863002217	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1123863002218	metal binding triad; other site
1123863002219	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1123863002220	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1123863002221	metal binding triad; other site
1123863002222	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1123863002223	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1123863002224	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1123863002225	putative ribose interaction site [chemical binding]; other site
1123863002226	putative ADP binding site [chemical binding]; other site
1123863002227	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1123863002228	active site
1123863002229	nucleotide binding site [chemical binding]; other site
1123863002230	HIGH motif; other site
1123863002231	KMSKS motif; other site
1123863002232	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1123863002233	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1123863002234	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1123863002235	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1123863002236	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1123863002237	putative active site [active]
1123863002238	metal binding site [ion binding]; metal-binding site
1123863002239	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1123863002240	hypothetical protein; Provisional; Region: PRK11653
1123863002241	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1123863002242	Legionella pneumophila major outer membrane protein precursor; Region: Legionella_OMP; pfam05150
1123863002243	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1123863002244	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1123863002245	dimer interface [polypeptide binding]; other site
1123863002246	ADP-ribose binding site [chemical binding]; other site
1123863002247	active site
1123863002248	nudix motif; other site
1123863002249	metal binding site [ion binding]; metal-binding site
1123863002250	putative dehydrogenase; Provisional; Region: PRK11039
1123863002251	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
1123863002252	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1123863002253	hexamer interface [polypeptide binding]; other site
1123863002254	active site
1123863002255	metal binding site [ion binding]; metal-binding site
1123863002256	esterase YqiA; Provisional; Region: PRK11071
1123863002257	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1123863002258	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1123863002259	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863002260	ATP binding site [chemical binding]; other site
1123863002261	Mg2+ binding site [ion binding]; other site
1123863002262	G-X-G motif; other site
1123863002263	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1123863002264	anchoring element; other site
1123863002265	dimer interface [polypeptide binding]; other site
1123863002266	ATP binding site [chemical binding]; other site
1123863002267	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1123863002268	active site
1123863002269	metal binding site [ion binding]; metal-binding site
1123863002270	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1123863002271	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1123863002272	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1123863002273	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863002274	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863002275	substrate binding pocket [chemical binding]; other site
1123863002276	membrane-bound complex binding site; other site
1123863002277	hinge residues; other site
1123863002278	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1123863002279	intersubunit interface [polypeptide binding]; other site
1123863002280	active site
1123863002281	zinc binding site [ion binding]; other site
1123863002282	Na+ binding site [ion binding]; other site
1123863002283	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1123863002284	intersubunit interface [polypeptide binding]; other site
1123863002285	active site
1123863002286	zinc binding site [ion binding]; other site
1123863002287	Na+ binding site [ion binding]; other site
1123863002288	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1123863002289	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1123863002290	active site
1123863002291	P-loop; other site
1123863002292	phosphorylation site [posttranslational modification]
1123863002293	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863002294	active site
1123863002295	phosphorylation site [posttranslational modification]
1123863002296	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1123863002297	PRD domain; Region: PRD; pfam00874
1123863002298	PRD domain; Region: PRD; pfam00874
1123863002299	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1123863002300	active site
1123863002301	P-loop; other site
1123863002302	phosphorylation site [posttranslational modification]
1123863002303	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1123863002304	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1123863002305	CAP-like domain; other site
1123863002306	active site
1123863002307	primary dimer interface [polypeptide binding]; other site
1123863002308	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1123863002309	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1123863002310	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1123863002311	putative acyl-acceptor binding pocket; other site
1123863002312	FtsI repressor; Provisional; Region: PRK10883
1123863002313	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1123863002314	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1123863002315	flagellin; Provisional; Region: PRK12802
1123863002316	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1123863002317	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1123863002318	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1123863002319	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1123863002320	active site
1123863002321	catalytic tetrad [active]
1123863002322	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1123863002323	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1123863002324	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863002325	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863002326	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1123863002327	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1123863002328	cystathionine beta-lyase; Provisional; Region: PRK08114
1123863002329	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1123863002330	homodimer interface [polypeptide binding]; other site
1123863002331	substrate-cofactor binding pocket; other site
1123863002332	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863002333	catalytic residue [active]
1123863002334	beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431
1123863002335	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1123863002336	Bacterial transcriptional regulator; Region: IclR; pfam01614
1123863002337	3-oxoacid CoA-transferase, A subunit; Region: pcaI_scoA_fam; TIGR02429
1123863002338	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1123863002339	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1123863002340	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1123863002341	dimer interface [polypeptide binding]; other site
1123863002342	active site
1123863002343	3-carboxy-cis,cis-muconate cycloisomerase; Provisional; Region: PRK09053
1123863002344	prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597
1123863002345	tetramer interface [polypeptide binding]; other site
1123863002346	active site
1123863002347	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
1123863002348	4-carboxymuconolactone decarboxylase; Region: decarb_PcaC; TIGR02425
1123863002349	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1123863002350	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863002351	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863002352	dimerization interface [polypeptide binding]; other site
1123863002353	Protocatechuate 3,4-dioxygenase beta subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PcaH; COG3485
1123863002354	Protocatechuate 3,4-dioxygenase (3,4-PCD) , alpha subunit. 3,4-PCD catalyzes the oxidative ring cleavage of 3,4-dihydroxybenzoate to produce beta-carboxy-cis,cis-muconate. 3,4-PCDs are large aggregates of 12 protomers, each composed of an alpha- and...; Region: 3,4-PCD_alpha; cd03463
1123863002355	heterodimer interface [polypeptide binding]; other site
1123863002356	active site
1123863002357	Protocatechuate 3,4-dioxygenase (3,4-PCD) , beta subunit. 3,4-PCD catalyzes the oxidative ring cleavage of 3,4-dihydroxybenzoate to produce beta-carboxy-cis,cis-muconate. 3,4-PCDs are large aggregates of 12 protomers, each composed of an alpha- and...; Region: 3,4-PCD_beta; cd03464
1123863002358	heterodimer interface [polypeptide binding]; other site
1123863002359	multimer interface [polypeptide binding]; other site
1123863002360	protocatechuate 3,4-dioxygenase, beta subunit; Region: protocat_beta; TIGR02422
1123863002361	active site
1123863002362	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1123863002363	4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only]; Region: COG3185
1123863002364	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
1123863002365	dimer interface [polypeptide binding]; other site
1123863002366	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
1123863002367	active site
1123863002368	Fe binding site [ion binding]; other site
1123863002369	benzoate transport; Region: 2A0115; TIGR00895
1123863002370	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002371	putative substrate translocation pore; other site
1123863002372	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1123863002373	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863002374	DNA binding site [nucleotide binding]
1123863002375	domain linker motif; other site
1123863002376	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1123863002377	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1123863002378	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1123863002379	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1123863002380	active site turn [active]
1123863002381	phosphorylation site [posttranslational modification]
1123863002382	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1123863002383	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
1123863002384	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1123863002385	citrate-proton symporter; Provisional; Region: PRK15075
1123863002386	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002387	putative substrate translocation pore; other site
1123863002388	Spore Coat Protein U domain; Region: SCPU; cl02253
1123863002389	Spore Coat Protein U domain; Region: SCPU; pfam05229
1123863002390	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1123863002391	PapC N-terminal domain; Region: PapC_N; pfam13954
1123863002392	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1123863002393	PapC C-terminal domain; Region: PapC_C; pfam13953
1123863002394	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1123863002395	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863002396	Spore Coat Protein U domain; Region: SCPU; pfam05229
1123863002397	Spore Coat Protein U domain; Region: SCPU; pfam05229
1123863002398	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1123863002399	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1123863002400	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1123863002401	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1123863002402	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863002403	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863002404	metal binding site [ion binding]; metal-binding site
1123863002405	active site
1123863002406	I-site; other site
1123863002407	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863002408	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1123863002409	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863002410	DNA-binding site [nucleotide binding]; DNA binding site
1123863002411	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863002412	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863002413	homodimer interface [polypeptide binding]; other site
1123863002414	catalytic residue [active]
1123863002415	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1123863002416	M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669
1123863002417	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1123863002418	metal binding site [ion binding]; metal-binding site
1123863002419	dimer interface [polypeptide binding]; other site
1123863002420	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1123863002421	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1123863002422	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1123863002423	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1123863002424	metal binding site [ion binding]; metal-binding site
1123863002425	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1123863002426	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1123863002427	active site
1123863002428	non-prolyl cis peptide bond; other site
1123863002429	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863002430	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863002431	substrate binding pocket [chemical binding]; other site
1123863002432	membrane-bound complex binding site; other site
1123863002433	hinge residues; other site
1123863002434	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1123863002435	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863002436	Coenzyme A binding pocket [chemical binding]; other site
1123863002437	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863002438	dimer interface [polypeptide binding]; other site
1123863002439	conserved gate region; other site
1123863002440	putative PBP binding loops; other site
1123863002441	ABC-ATPase subunit interface; other site
1123863002442	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1123863002443	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863002444	Walker A/P-loop; other site
1123863002445	ATP binding site [chemical binding]; other site
1123863002446	Q-loop/lid; other site
1123863002447	ABC transporter signature motif; other site
1123863002448	Walker B; other site
1123863002449	D-loop; other site
1123863002450	H-loop/switch region; other site
1123863002451	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863002452	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863002453	substrate binding pocket [chemical binding]; other site
1123863002454	membrane-bound complex binding site; other site
1123863002455	hinge residues; other site
1123863002456	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863002457	Uncharacterized protein containing double-stranded beta helix domain [Function unknown]; Region: COG4297
1123863002458	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
1123863002459	putative acyl-acceptor binding pocket; other site
1123863002460	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1123863002461	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1123863002462	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863002463	Walker A/P-loop; other site
1123863002464	ATP binding site [chemical binding]; other site
1123863002465	Q-loop/lid; other site
1123863002466	ABC transporter signature motif; other site
1123863002467	Walker B; other site
1123863002468	D-loop; other site
1123863002469	H-loop/switch region; other site
1123863002470	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1123863002471	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1123863002472	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1123863002473	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863002474	dimer interface [polypeptide binding]; other site
1123863002475	conserved gate region; other site
1123863002476	putative PBP binding loops; other site
1123863002477	ABC-ATPase subunit interface; other site
1123863002478	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863002479	dimer interface [polypeptide binding]; other site
1123863002480	conserved gate region; other site
1123863002481	putative PBP binding loops; other site
1123863002482	ABC-ATPase subunit interface; other site
1123863002483	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1123863002484	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863002485	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863002486	DNA binding site [nucleotide binding]
1123863002487	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1123863002488	ligand binding site [chemical binding]; other site
1123863002489	dimerization interface [polypeptide binding]; other site
1123863002490	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002491	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863002492	putative substrate translocation pore; other site
1123863002493	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1123863002494	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1123863002495	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
1123863002496	putative active site [active]
1123863002497	putative catalytic site [active]
1123863002498	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1123863002499	Ferritin-like domain; Region: Ferritin; pfam00210
1123863002500	ferroxidase diiron center [ion binding]; other site
1123863002501	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1123863002502	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1123863002503	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1123863002504	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1123863002505	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1123863002506	G1 box; other site
1123863002507	putative GEF interaction site [polypeptide binding]; other site
1123863002508	GTP/Mg2+ binding site [chemical binding]; other site
1123863002509	Switch I region; other site
1123863002510	G2 box; other site
1123863002511	G3 box; other site
1123863002512	Switch II region; other site
1123863002513	G4 box; other site
1123863002514	G5 box; other site
1123863002515	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1123863002516	periplasmic protein; Provisional; Region: PRK10568
1123863002517	BON domain; Region: BON; pfam04972
1123863002518	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1123863002519	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1123863002520	active site
1123863002521	nucleophile elbow; other site
1123863002522	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1123863002523	active site
1123863002524	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1123863002525	intersubunit interface [polypeptide binding]; other site
1123863002526	active site
1123863002527	catalytic residue [active]
1123863002528	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1123863002529	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1123863002530	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1123863002531	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1123863002532	phosphopentomutase; Provisional; Region: PRK05362
1123863002533	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1123863002534	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1123863002535	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1123863002536	penicillin-binding protein 2; Provisional; Region: PRK10795
1123863002537	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1123863002538	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1123863002539	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863002540	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863002541	metal binding site [ion binding]; metal-binding site
1123863002542	active site
1123863002543	I-site; other site
1123863002544	Domain of unknown function (DUF1987); Region: DUF1987; pfam09345
1123863002545	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1123863002546	FOG: CBS domain [General function prediction only]; Region: COG0517
1123863002547	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1123863002548	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1123863002549	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1123863002550	tetramer interface [polypeptide binding]; other site
1123863002551	active site
1123863002552	Mg2+/Mn2+ binding site [ion binding]; other site
1123863002553	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1123863002554	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1123863002555	non-prolyl cis peptide bond; other site
1123863002556	active site
1123863002557	trans-homoaconitate synthase; Reviewed; Region: aksA; PRK11858
1123863002558	Streptomyces rubellomurinus FrbC and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_NifV; cd07939
1123863002559	active site
1123863002560	catalytic residues [active]
1123863002561	metal binding site [ion binding]; metal-binding site
1123863002562	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1123863002563	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1123863002564	substrate binding site [chemical binding]; other site
1123863002565	ligand binding site [chemical binding]; other site
1123863002566	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863002567	S-adenosylmethionine binding site [chemical binding]; other site
1123863002568	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1123863002569	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863002570	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1123863002571	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1123863002572	Integrase core domain; Region: rve_3; pfam13683
1123863002573	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002574	metabolite-proton symporter; Region: 2A0106; TIGR00883
1123863002575	putative substrate translocation pore; other site
1123863002576	hypothetical protein; Provisional; Region: PRK07079
1123863002577	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_2; cd05679
1123863002578	metal binding site [ion binding]; metal-binding site
1123863002579	putative dimer interface [polypeptide binding]; other site
1123863002580	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863002581	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863002582	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863002583	dimerization interface [polypeptide binding]; other site
1123863002584	EamA-like transporter family; Region: EamA; pfam00892
1123863002585	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1123863002586	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002587	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863002588	putative substrate translocation pore; other site
1123863002589	Predicted transcriptional regulators [Transcription]; Region: COG1733
1123863002590	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1123863002591	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002592	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
1123863002593	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
1123863002594	active site
1123863002595	catalytic residues [active]
1123863002596	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5255
1123863002597	Domain of unknown function (DUF1868); Region: 2H-phosphodiest; pfam08975
1123863002598	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863002599	PAS domain; Region: PAS_9; pfam13426
1123863002600	putative active site [active]
1123863002601	heme pocket [chemical binding]; other site
1123863002602	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863002603	PAS domain; Region: PAS_9; pfam13426
1123863002604	putative active site [active]
1123863002605	heme pocket [chemical binding]; other site
1123863002606	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1123863002607	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863002608	dimer interface [polypeptide binding]; other site
1123863002609	putative CheW interface [polypeptide binding]; other site
1123863002610	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863002611	PAS domain; Region: PAS_9; pfam13426
1123863002612	putative active site [active]
1123863002613	heme pocket [chemical binding]; other site
1123863002614	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863002615	PAS domain; Region: PAS_9; pfam13426
1123863002616	putative active site [active]
1123863002617	heme pocket [chemical binding]; other site
1123863002618	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1123863002619	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863002620	dimer interface [polypeptide binding]; other site
1123863002621	putative CheW interface [polypeptide binding]; other site
1123863002622	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1123863002623	active site
1123863002624	CHASE3 domain; Region: CHASE3; pfam05227
1123863002625	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863002626	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863002627	dimer interface [polypeptide binding]; other site
1123863002628	putative CheW interface [polypeptide binding]; other site
1123863002629	hypothetical protein; Provisional; Region: PRK10316
1123863002630	YfdX protein; Region: YfdX; pfam10938
1123863002631	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863002632	putative active site [active]
1123863002633	PAS fold; Region: PAS_3; pfam08447
1123863002634	heme pocket [chemical binding]; other site
1123863002635	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863002636	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863002637	metal binding site [ion binding]; metal-binding site
1123863002638	active site
1123863002639	I-site; other site
1123863002640	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1123863002641	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1123863002642	TAP-like protein; Region: Abhydrolase_4; pfam08386
1123863002643	General stress protein [General function prediction only]; Region: GsiB; COG3729
1123863002644	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1123863002645	dinuclear metal binding motif [ion binding]; other site
1123863002646	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
1123863002647	trehalase; Provisional; Region: treF; PRK13270
1123863002648	Trehalase; Region: Trehalase; cl17346
1123863002649	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1123863002650	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1123863002651	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863002652	putative DNA binding site [nucleotide binding]; other site
1123863002653	dimerization interface [polypeptide binding]; other site
1123863002654	putative Zn2+ binding site [ion binding]; other site
1123863002655	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1123863002656	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1123863002657	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1123863002658	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1123863002659	NADP binding site [chemical binding]; other site
1123863002660	Predicted transcriptional regulators [Transcription]; Region: COG1733
1123863002661	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1123863002662	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1123863002663	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1123863002664	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1123863002665	Protein of unknown function (DUF2474); Region: DUF2474; pfam10617
1123863002666	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1123863002667	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863002668	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1123863002669	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1123863002670	FAD binding pocket [chemical binding]; other site
1123863002671	FAD binding motif [chemical binding]; other site
1123863002672	phosphate binding motif [ion binding]; other site
1123863002673	NAD binding pocket [chemical binding]; other site
1123863002674	Predicted transcriptional regulators [Transcription]; Region: COG1695
1123863002675	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1123863002676	Rdx family; Region: Rdx; cl01407
1123863002677	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1123863002678	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1123863002679	NADP binding site [chemical binding]; other site
1123863002680	dimer interface [polypeptide binding]; other site
1123863002681	ornithine decarboxylase; Provisional; Region: PRK13578
1123863002682	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1123863002683	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1123863002684	homodimer interface [polypeptide binding]; other site
1123863002685	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863002686	catalytic residue [active]
1123863002687	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1123863002688	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1123863002689	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1123863002690	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1123863002691	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1123863002692	catalytic residue [active]
1123863002693	oxidative damage protection protein; Provisional; Region: PRK05408
1123863002694	adenine DNA glycosylase; Provisional; Region: PRK10880
1123863002695	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1123863002696	minor groove reading motif; other site
1123863002697	helix-hairpin-helix signature motif; other site
1123863002698	substrate binding pocket [chemical binding]; other site
1123863002699	active site
1123863002700	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1123863002701	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1123863002702	DNA binding and oxoG recognition site [nucleotide binding]
1123863002703	melibiose:sodium symporter; Provisional; Region: PRK10429
1123863002704	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1123863002705	alpha-galactosidase; Provisional; Region: PRK15076
1123863002706	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1123863002707	NAD binding site [chemical binding]; other site
1123863002708	sugar binding site [chemical binding]; other site
1123863002709	divalent metal binding site [ion binding]; other site
1123863002710	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1123863002711	dimer interface [polypeptide binding]; other site
1123863002712	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1123863002713	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863002714	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863002715	Predicted S-adenosylmethionine-dependent methyltransferase [General function prediction only]; Region: COG0220
1123863002716	hypothetical protein; Provisional; Region: PRK11702
1123863002717	hypothetical protein; Provisional; Region: PRK10626
1123863002718	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1123863002719	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1123863002720	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1123863002721	active site
1123863002722	P-loop; other site
1123863002723	phosphorylation site [posttranslational modification]
1123863002724	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863002725	active site
1123863002726	phosphorylation site [posttranslational modification]
1123863002727	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
1123863002728	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863002729	DNA-binding site [nucleotide binding]; DNA binding site
1123863002730	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1123863002731	HemN family oxidoreductase; Provisional; Region: PRK05660
1123863002732	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863002733	FeS/SAM binding site; other site
1123863002734	HemN C-terminal domain; Region: HemN_C; pfam06969
1123863002735	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1123863002736	active site
1123863002737	dimerization interface [polypeptide binding]; other site
1123863002738	YGGT family; Region: YGGT; pfam02325
1123863002739	Predicted integral membrane protein [Function unknown]; Region: COG0762
1123863002740	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1123863002741	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1123863002742	catalytic residue [active]
1123863002743	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1123863002744	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1123863002745	Walker A motif; other site
1123863002746	ATP binding site [chemical binding]; other site
1123863002747	Walker B motif; other site
1123863002748	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1123863002749	hypothetical protein; Validated; Region: PRK00228
1123863002750	glutathione synthetase; Provisional; Region: PRK05246
1123863002751	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1123863002752	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1123863002753	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1123863002754	RNA methyltransferase, RsmE family; Region: TIGR00046
1123863002755	DNA-specific endonuclease I; Provisional; Region: PRK15137
1123863002756	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1123863002757	hypothetical protein; Provisional; Region: PRK04860
1123863002758	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1123863002759	Cache domain; Region: Cache_1; pfam02743
1123863002760	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863002761	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863002762	dimer interface [polypeptide binding]; other site
1123863002763	putative CheW interface [polypeptide binding]; other site
1123863002764	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1123863002765	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002766	putative substrate translocation pore; other site
1123863002767	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002768	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1123863002769	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1123863002770	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1123863002771	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1123863002772	arginine decarboxylase; Provisional; Region: PRK05354
1123863002773	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1123863002774	dimer interface [polypeptide binding]; other site
1123863002775	active site
1123863002776	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1123863002777	catalytic residues [active]
1123863002778	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1123863002779	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1123863002780	agmatinase; Region: agmatinase; TIGR01230
1123863002781	oligomer interface [polypeptide binding]; other site
1123863002782	putative active site [active]
1123863002783	Mn binding site [ion binding]; other site
1123863002784	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1123863002785	transketolase; Reviewed; Region: PRK12753
1123863002786	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1123863002787	TPP-binding site [chemical binding]; other site
1123863002788	dimer interface [polypeptide binding]; other site
1123863002789	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1123863002790	PYR/PP interface [polypeptide binding]; other site
1123863002791	dimer interface [polypeptide binding]; other site
1123863002792	TPP binding site [chemical binding]; other site
1123863002793	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1123863002794	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1123863002795	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1123863002796	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1123863002797	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1123863002798	Phosphoglycerate kinase; Region: PGK; pfam00162
1123863002799	substrate binding site [chemical binding]; other site
1123863002800	hinge regions; other site
1123863002801	ADP binding site [chemical binding]; other site
1123863002802	catalytic site [active]
1123863002803	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1123863002804	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1123863002805	active site
1123863002806	intersubunit interface [polypeptide binding]; other site
1123863002807	zinc binding site [ion binding]; other site
1123863002808	Na+ binding site [ion binding]; other site
1123863002809	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_5; cd07238
1123863002810	dimer interface [polypeptide binding]; other site
1123863002811	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863002812	mechanosensitive channel MscS; Provisional; Region: PRK10334
1123863002813	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1123863002814	LysE type translocator; Region: LysE; cl00565
1123863002815	oxidative stress defense protein; Provisional; Region: PRK11087
1123863002816	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1123863002817	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1123863002818	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863002819	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1123863002820	putative dimerization interface [polypeptide binding]; other site
1123863002821	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1123863002822	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1123863002823	active site
1123863002824	dimer interface [polypeptide binding]; other site
1123863002825	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1123863002826	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1123863002827	ligand binding site [chemical binding]; other site
1123863002828	NAD binding site [chemical binding]; other site
1123863002829	tetramer interface [polypeptide binding]; other site
1123863002830	catalytic site [active]
1123863002831	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1123863002832	L-serine binding site [chemical binding]; other site
1123863002833	ACT domain interface; other site
1123863002834	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1123863002835	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
1123863002836	Z-ring-associated protein; Provisional; Region: PRK10972
1123863002837	hypothetical protein; Reviewed; Region: PRK01736
1123863002838	proline aminopeptidase P II; Provisional; Region: PRK10879
1123863002839	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1123863002840	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1123863002841	active site
1123863002842	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1123863002843	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
1123863002844	oxidoreductase; Provisional; Region: PRK08013
1123863002845	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1123863002846	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1123863002847	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1123863002848	glycine cleavage system protein H; Provisional; Region: PRK13380
1123863002849	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1123863002850	lipoyl attachment site [posttranslational modification]; other site
1123863002851	glycine dehydrogenase; Provisional; Region: PRK05367
1123863002852	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1123863002853	tetramer interface [polypeptide binding]; other site
1123863002854	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863002855	catalytic residue [active]
1123863002856	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1123863002857	tetramer interface [polypeptide binding]; other site
1123863002858	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863002859	catalytic residue [active]
1123863002860	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
1123863002861	classical (c) SDRs; Region: SDR_c; cd05233
1123863002862	NAD(P) binding site [chemical binding]; other site
1123863002863	active site
1123863002864	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1123863002865	beta-galactosidase; Region: BGL; TIGR03356
1123863002866	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1123863002867	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863002868	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1123863002869	hemolysin; Provisional; Region: PRK15087
1123863002870	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1123863002871	putative global regulator; Reviewed; Region: PRK09559
1123863002872	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1123863002873	Flavinator of succinate dehydrogenase; Region: Sdh5; cl01110
1123863002874	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1123863002875	flavodoxin FldB; Provisional; Region: PRK12359
1123863002876	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1123863002877	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1123863002878	active site
1123863002879	Int/Topo IB signature motif; other site
1123863002880	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1123863002881	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1123863002882	dimerization domain [polypeptide binding]; other site
1123863002883	dimer interface [polypeptide binding]; other site
1123863002884	catalytic residues [active]
1123863002885	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1123863002886	DHH family; Region: DHH; pfam01368
1123863002887	DHHA1 domain; Region: DHHA1; pfam02272
1123863002888	peptide chain release factor 2; Validated; Region: prfB; PRK00578
1123863002889	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1123863002890	RF-1 domain; Region: RF-1; pfam00472
1123863002891	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1123863002892	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1123863002893	dimer interface [polypeptide binding]; other site
1123863002894	putative anticodon binding site; other site
1123863002895	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1123863002896	motif 1; other site
1123863002897	active site
1123863002898	motif 2; other site
1123863002899	motif 3; other site
1123863002900	Cupin domain; Region: Cupin_2; cl17218
1123863002901	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1123863002902	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863002903	putative substrate translocation pore; other site
1123863002904	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1123863002905	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863002906	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863002907	dimerization interface [polypeptide binding]; other site
1123863002908	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1123863002909	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1123863002910	active site
1123863002911	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1123863002912	substrate binding site [chemical binding]; other site
1123863002913	catalytic residues [active]
1123863002914	dimer interface [polypeptide binding]; other site
1123863002915	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1123863002916	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1123863002917	active site
1123863002918	catalytic tetrad [active]
1123863002919	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1123863002920	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1123863002921	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1123863002922	putative DNA-binding cleft [nucleotide binding]; other site
1123863002923	putative DNA clevage site; other site
1123863002924	molecular lever; other site
1123863002925	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1123863002926	putative active site [active]
1123863002927	Ap4A binding site [chemical binding]; other site
1123863002928	nudix motif; other site
1123863002929	putative metal binding site [ion binding]; other site
1123863002930	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1123863002931	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1123863002932	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1123863002933	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1123863002934	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1123863002935	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1123863002936	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1123863002937	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1123863002938	dimerization interface [polypeptide binding]; other site
1123863002939	active site
1123863002940	hypothetical protein; Provisional; Region: PRK10506
1123863002941	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1123863002942	hypothetical protein; Provisional; Region: PRK10557
1123863002943	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1123863002944	Protein of unknown function (DUF2509); Region: DUF2509; cl11672
1123863002945	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1123863002946	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1123863002947	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1123863002948	protease3; Provisional; Region: PRK15101
1123863002949	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1123863002950	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1123863002951	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1123863002952	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1123863002953	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
1123863002954	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1123863002955	AAA domain; Region: AAA_30; pfam13604
1123863002956	Family description; Region: UvrD_C_2; pfam13538
1123863002957	N-acetylglutamate synthase; Validated; Region: PRK05279
1123863002958	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1123863002959	putative feedback inhibition sensing region; other site
1123863002960	putative nucleotide binding site [chemical binding]; other site
1123863002961	putative substrate binding site [chemical binding]; other site
1123863002962	N-acetylglutamate synthase and related acetyltransferases [Amino acid transport and metabolism]; Region: ArgA; COG1246
1123863002963	AMIN domain; Region: AMIN; pfam11741
1123863002964	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1123863002965	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1123863002966	active site
1123863002967	metal binding site [ion binding]; metal-binding site
1123863002968	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1123863002969	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1123863002970	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863002971	catalytic residue [active]
1123863002972	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1123863002973	MltA specific insert domain; Region: MltA; smart00925
1123863002974	3D domain; Region: 3D; pfam06725
1123863002975	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1123863002976	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1123863002977	putative ATP binding site [chemical binding]; other site
1123863002978	putative substrate interface [chemical binding]; other site
1123863002979	cysteine desulfurase, sulfur acceptor subunit CsdE; Region: FeS_syn_CsdE; TIGR03391
1123863002980	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1123863002981	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1123863002982	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863002983	catalytic residue [active]
1123863002984	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1123863002985	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1123863002986	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863002987	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1123863002988	dimerization interface [polypeptide binding]; other site
1123863002989	substrate binding pocket [chemical binding]; other site
1123863002990	hypothetical protein; Provisional; Region: PRK10873
1123863002991	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1123863002992	N-Utilization Substance G (NusG) N-terminal (NGN) domain Superfamily; Region: NGN; cl02766
1123863002993	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1123863002994	flap endonuclease-like protein; Provisional; Region: PRK09482
1123863002995	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1123863002996	active site
1123863002997	metal binding site 1 [ion binding]; metal-binding site
1123863002998	putative 5' ssDNA interaction site; other site
1123863002999	metal binding site 3; metal-binding site
1123863003000	metal binding site 2 [ion binding]; metal-binding site
1123863003001	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1123863003002	putative DNA binding site [nucleotide binding]; other site
1123863003003	putative metal binding site [ion binding]; other site
1123863003004	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1123863003005	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1123863003006	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1123863003007	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1123863003008	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1123863003009	SecY interacting protein Syd; Provisional; Region: PRK04968
1123863003010	tRNA pseudouridine synthase C; Region: DUF446; pfam04287
1123863003011	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1123863003012	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1123863003013	probable active site [active]
1123863003014	flavodoxin; Provisional; Region: PRK08105
1123863003015	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1123863003016	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1123863003017	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1123863003018	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863003019	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863003020	putative substrate translocation pore; other site
1123863003021	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1123863003022	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1123863003023	active site
1123863003024	tetramer interface [polypeptide binding]; other site
1123863003025	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1123863003026	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1123863003027	active site
1123863003028	tetramer interface [polypeptide binding]; other site
1123863003029	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1123863003030	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1123863003031	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1123863003032	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1123863003033	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1123863003034	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1123863003035	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863003036	dimerization interface [polypeptide binding]; other site
1123863003037	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863003038	dimer interface [polypeptide binding]; other site
1123863003039	phosphorylation site [posttranslational modification]
1123863003040	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863003041	ATP binding site [chemical binding]; other site
1123863003042	Mg2+ binding site [ion binding]; other site
1123863003043	G-X-G motif; other site
1123863003044	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1123863003045	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863003046	active site
1123863003047	phosphorylation site [posttranslational modification]
1123863003048	intermolecular recognition site; other site
1123863003049	dimerization interface [polypeptide binding]; other site
1123863003050	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1123863003051	putative binding surface; other site
1123863003052	active site
1123863003053	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1123863003054	TRAM domain; Region: TRAM; pfam01938
1123863003055	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863003056	S-adenosylmethionine binding site [chemical binding]; other site
1123863003057	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1123863003058	HD domain; Region: HD_4; pfam13328
1123863003059	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1123863003060	synthetase active site [active]
1123863003061	NTP binding site [chemical binding]; other site
1123863003062	metal binding site [ion binding]; metal-binding site
1123863003063	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1123863003064	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1123863003065	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1123863003066	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1123863003067	homodimer interface [polypeptide binding]; other site
1123863003068	metal binding site [ion binding]; metal-binding site
1123863003069	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1123863003070	homodimer interface [polypeptide binding]; other site
1123863003071	active site
1123863003072	putative chemical substrate binding site [chemical binding]; other site
1123863003073	metal binding site [ion binding]; metal-binding site
1123863003074	CTP synthetase; Validated; Region: pyrG; PRK05380
1123863003075	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1123863003076	Catalytic site [active]
1123863003077	active site
1123863003078	UTP binding site [chemical binding]; other site
1123863003079	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1123863003080	active site
1123863003081	putative oxyanion hole; other site
1123863003082	catalytic triad [active]
1123863003083	enolase; Provisional; Region: eno; PRK00077
1123863003084	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1123863003085	dimer interface [polypeptide binding]; other site
1123863003086	metal binding site [ion binding]; metal-binding site
1123863003087	substrate binding pocket [chemical binding]; other site
1123863003088	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1123863003089	putative catalytic site [active]
1123863003090	putative phosphate binding site [ion binding]; other site
1123863003091	putative metal binding site [ion binding]; other site
1123863003092	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
1123863003093	M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme; Region: M20_CPDG2; cd03885
1123863003094	metal binding site [ion binding]; metal-binding site
1123863003095	dimer interface [polypeptide binding]; other site
1123863003096	hypothetical protein; Provisional; Region: PRK10519
1123863003097	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1123863003098	Nucleoside recognition; Region: Gate; pfam07670
1123863003099	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1123863003100	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1123863003101	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1123863003102	dimer interface [polypeptide binding]; other site
1123863003103	substrate binding site [chemical binding]; other site
1123863003104	metal binding sites [ion binding]; metal-binding site
1123863003105	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1123863003106	active site
1123863003107	N-acetyltransferase; Region: Acetyltransf_2; cl00949
1123863003108	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1123863003109	Flavodoxin; Region: Flavodoxin_1; pfam00258
1123863003110	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1123863003111	FAD binding pocket [chemical binding]; other site
1123863003112	FAD binding motif [chemical binding]; other site
1123863003113	catalytic residues [active]
1123863003114	NAD binding pocket [chemical binding]; other site
1123863003115	phosphate binding motif [ion binding]; other site
1123863003116	beta-alpha-beta structure motif; other site
1123863003117	sulfite reductase subunit beta; Provisional; Region: PRK13504
1123863003118	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1123863003119	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1123863003120	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1123863003121	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1123863003122	Active Sites [active]
1123863003123	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
1123863003124	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase; Region: PLPDE_III_cryptic_DSD; cd06818
1123863003125	active site
1123863003126	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1123863003127	dimer interface [polypeptide binding]; other site
1123863003128	substrate binding site [chemical binding]; other site
1123863003129	catalytic residue [active]
1123863003130	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1123863003131	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863003132	Walker A/P-loop; other site
1123863003133	ATP binding site [chemical binding]; other site
1123863003134	Q-loop/lid; other site
1123863003135	ABC transporter signature motif; other site
1123863003136	Walker B; other site
1123863003137	D-loop; other site
1123863003138	H-loop/switch region; other site
1123863003139	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863003140	dimer interface [polypeptide binding]; other site
1123863003141	conserved gate region; other site
1123863003142	putative PBP binding loops; other site
1123863003143	ABC-ATPase subunit interface; other site
1123863003144	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863003145	dimer interface [polypeptide binding]; other site
1123863003146	conserved gate region; other site
1123863003147	putative PBP binding loops; other site
1123863003148	ABC-ATPase subunit interface; other site
1123863003149	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863003150	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863003151	substrate binding pocket [chemical binding]; other site
1123863003152	membrane-bound complex binding site; other site
1123863003153	hinge residues; other site
1123863003154	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1123863003155	homotrimer interaction site [polypeptide binding]; other site
1123863003156	putative active site [active]
1123863003157	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1123863003158	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
1123863003159	Bacterial transcriptional regulator; Region: IclR; pfam01614
1123863003160	YCII-related domain; Region: YCII; cl00999
1123863003161	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1123863003162	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1123863003163	metal binding site [ion binding]; metal-binding site
1123863003164	siroheme synthase; Provisional; Region: cysG; PRK10637
1123863003165	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1123863003166	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1123863003167	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1123863003168	active site
1123863003169	SAM binding site [chemical binding]; other site
1123863003170	homodimer interface [polypeptide binding]; other site
1123863003171	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1123863003172	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1123863003173	Active Sites [active]
1123863003174	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1123863003175	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1123863003176	CysD dimerization site [polypeptide binding]; other site
1123863003177	G1 box; other site
1123863003178	putative GEF interaction site [polypeptide binding]; other site
1123863003179	GTP/Mg2+ binding site [chemical binding]; other site
1123863003180	Switch I region; other site
1123863003181	G2 box; other site
1123863003182	G3 box; other site
1123863003183	Switch II region; other site
1123863003184	G4 box; other site
1123863003185	G5 box; other site
1123863003186	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1123863003187	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1123863003188	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1123863003189	ligand-binding site [chemical binding]; other site
1123863003190	hypothetical protein; Provisional; Region: PRK10726
1123863003191	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1123863003192	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1123863003193	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1123863003194	substrate binding site; other site
1123863003195	dimer interface; other site
1123863003196	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1123863003197	homotrimer interaction site [polypeptide binding]; other site
1123863003198	zinc binding site [ion binding]; other site
1123863003199	CDP-binding sites; other site
1123863003200	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1123863003201	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1123863003202	Permutation of conserved domain; other site
1123863003203	active site
1123863003204	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1123863003205	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1123863003206	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1123863003207	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863003208	S-adenosylmethionine binding site [chemical binding]; other site
1123863003209	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1123863003210	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1123863003211	Peptidase family M23; Region: Peptidase_M23; pfam01551
1123863003212	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1123863003213	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1123863003214	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863003215	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1123863003216	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1123863003217	DNA binding residues [nucleotide binding]
1123863003218	2-phosphosulpholactate phosphatase; Region: 2-ph_phosp; cl00895
1123863003219	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1123863003220	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863003221	non-specific DNA binding site [nucleotide binding]; other site
1123863003222	salt bridge; other site
1123863003223	sequence-specific DNA binding site [nucleotide binding]; other site
1123863003224	2TM domain; Region: 2TM; pfam13239
1123863003225	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1123863003226	MutS domain I; Region: MutS_I; pfam01624
1123863003227	MutS domain II; Region: MutS_II; pfam05188
1123863003228	MutS domain III; Region: MutS_III; pfam05192
1123863003229	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1123863003230	Walker A/P-loop; other site
1123863003231	ATP binding site [chemical binding]; other site
1123863003232	Q-loop/lid; other site
1123863003233	ABC transporter signature motif; other site
1123863003234	Walker B; other site
1123863003235	D-loop; other site
1123863003236	H-loop/switch region; other site
1123863003237	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1123863003238	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1123863003239	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1123863003240	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1123863003241	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1123863003242	PhnA protein; Region: PhnA; pfam03831
1123863003243	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
1123863003244	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863003245	S-adenosylmethionine binding site [chemical binding]; other site
1123863003246	hypothetical protein; Validated; Region: PRK03661
1123863003247	recombinase A; Provisional; Region: recA; PRK09354
1123863003248	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1123863003249	hexamer interface [polypeptide binding]; other site
1123863003250	Walker A motif; other site
1123863003251	ATP binding site [chemical binding]; other site
1123863003252	Walker B motif; other site
1123863003253	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1123863003254	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1123863003255	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1123863003256	motif 1; other site
1123863003257	active site
1123863003258	motif 2; other site
1123863003259	motif 3; other site
1123863003260	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1123863003261	DHHA1 domain; Region: DHHA1; pfam02272
1123863003262	carbon storage regulator; Provisional; Region: PRK01712
1123863003263	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1123863003264	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863003265	motif II; other site
1123863003266	Predicted membrane protein [Function unknown]; Region: COG1238
1123863003267	glutamate--cysteine ligase; Provisional; Region: PRK02107
1123863003268	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1123863003269	hypothetical protein; Provisional; Region: PRK11573
1123863003270	Domain of unknown function DUF21; Region: DUF21; pfam01595
1123863003271	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1123863003272	Transporter associated domain; Region: CorC_HlyC; smart01091
1123863003273	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1123863003274	signal recognition particle protein; Provisional; Region: PRK10867
1123863003275	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1123863003276	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1123863003277	P loop; other site
1123863003278	GTP binding site [chemical binding]; other site
1123863003279	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1123863003280	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1123863003281	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1123863003282	RimM N-terminal domain; Region: RimM; pfam01782
1123863003283	PRC-barrel domain; Region: PRC; pfam05239
1123863003284	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1123863003285	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1123863003286	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1123863003287	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1123863003288	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1123863003289	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1123863003290	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1123863003291	Chorismate mutase type II; Region: CM_2; cl00693
1123863003292	prephenate dehydrogenase; Validated; Region: PRK08507
1123863003293	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1123863003294	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1123863003295	Prephenate dehydratase; Region: PDT; pfam00800
1123863003296	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1123863003297	putative L-Phe binding site [chemical binding]; other site
1123863003298	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1123863003299	30S subunit binding site; other site
1123863003300	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1123863003301	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1123863003302	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1123863003303	RNA binding surface [nucleotide binding]; other site
1123863003304	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1123863003305	active site
1123863003306	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
1123863003307	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1123863003308	protein disaggregation chaperone; Provisional; Region: PRK10865
1123863003309	Clp amino terminal domain; Region: Clp_N; pfam02861
1123863003310	Clp amino terminal domain; Region: Clp_N; pfam02861
1123863003311	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863003312	Walker A motif; other site
1123863003313	ATP binding site [chemical binding]; other site
1123863003314	Walker B motif; other site
1123863003315	arginine finger; other site
1123863003316	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863003317	Walker A motif; other site
1123863003318	ATP binding site [chemical binding]; other site
1123863003319	Walker B motif; other site
1123863003320	arginine finger; other site
1123863003321	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1123863003322	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1123863003323	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1123863003324	putative DNA binding site [nucleotide binding]; other site
1123863003325	putative Zn2+ binding site [ion binding]; other site
1123863003326	AsnC family; Region: AsnC_trans_reg; pfam01037
1123863003327	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1123863003328	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH6; cd08260
1123863003329	putative NAD(P) binding site [chemical binding]; other site
1123863003330	catalytic Zn binding site [ion binding]; other site
1123863003331	structural Zn binding site [ion binding]; other site
1123863003332	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1123863003333	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863003334	putative substrate translocation pore; other site
1123863003335	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1123863003336	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1123863003337	domain interface [polypeptide binding]; other site
1123863003338	putative active site [active]
1123863003339	catalytic site [active]
1123863003340	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1123863003341	domain interface [polypeptide binding]; other site
1123863003342	putative active site [active]
1123863003343	catalytic site [active]
1123863003344	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1123863003345	CoA binding domain; Region: CoA_binding_2; pfam13380
1123863003346	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1123863003347	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1123863003348	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1123863003349	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1123863003350	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1123863003351	thioredoxin 2; Provisional; Region: PRK10996
1123863003352	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1123863003353	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1123863003354	catalytic residues [active]
1123863003355	putative methyltransferase; Provisional; Region: PRK10864
1123863003356	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1123863003357	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1123863003358	Predicted transcriptional regulators [Transcription]; Region: COG1733
1123863003359	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1123863003360	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1123863003361	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1123863003362	putative NAD(P) binding site [chemical binding]; other site
1123863003363	putative substrate binding site [chemical binding]; other site
1123863003364	catalytic Zn binding site [ion binding]; other site
1123863003365	structural Zn binding site [ion binding]; other site
1123863003366	dimer interface [polypeptide binding]; other site
1123863003367	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1123863003368	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863003369	putative substrate translocation pore; other site
1123863003370	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863003371	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1123863003372	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863003373	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863003374	transcriptional repressor MprA; Provisional; Region: PRK10870
1123863003375	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1123863003376	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1123863003377	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863003378	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1123863003379	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1123863003380	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1123863003381	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863003382	dimer interface [polypeptide binding]; other site
1123863003383	conserved gate region; other site
1123863003384	putative PBP binding loops; other site
1123863003385	ABC-ATPase subunit interface; other site
1123863003386	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1123863003387	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1123863003388	Walker A/P-loop; other site
1123863003389	ATP binding site [chemical binding]; other site
1123863003390	Q-loop/lid; other site
1123863003391	ABC transporter signature motif; other site
1123863003392	Walker B; other site
1123863003393	D-loop; other site
1123863003394	H-loop/switch region; other site
1123863003395	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1123863003396	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1123863003397	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1123863003398	dimer interface [polypeptide binding]; other site
1123863003399	putative radical transfer pathway; other site
1123863003400	diiron center [ion binding]; other site
1123863003401	tyrosyl radical; other site
1123863003402	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1123863003403	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1123863003404	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1123863003405	active site
1123863003406	dimer interface [polypeptide binding]; other site
1123863003407	catalytic residues [active]
1123863003408	effector binding site; other site
1123863003409	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1123863003410	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1123863003411	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1123863003412	catalytic residues [active]
1123863003413	Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888
1123863003414	hypothetical protein; Provisional; Region: PRK10556
1123863003415	S-methylmethionine transporter; Provisional; Region: PRK11387
1123863003416	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
1123863003417	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1123863003418	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1123863003419	PEGA domain; Region: PEGA; pfam08308
1123863003420	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1123863003421	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863003422	Coenzyme A binding pocket [chemical binding]; other site
1123863003423	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1123863003424	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863003425	Walker A/P-loop; other site
1123863003426	ATP binding site [chemical binding]; other site
1123863003427	Q-loop/lid; other site
1123863003428	ABC transporter signature motif; other site
1123863003429	Walker B; other site
1123863003430	D-loop; other site
1123863003431	H-loop/switch region; other site
1123863003432	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1123863003433	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863003434	Walker A/P-loop; other site
1123863003435	ATP binding site [chemical binding]; other site
1123863003436	Q-loop/lid; other site
1123863003437	ABC transporter signature motif; other site
1123863003438	Walker B; other site
1123863003439	D-loop; other site
1123863003440	H-loop/switch region; other site
1123863003441	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1123863003442	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1123863003443	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863003444	dimer interface [polypeptide binding]; other site
1123863003445	conserved gate region; other site
1123863003446	ABC-ATPase subunit interface; other site
1123863003447	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1123863003448	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863003449	dimer interface [polypeptide binding]; other site
1123863003450	conserved gate region; other site
1123863003451	putative PBP binding loops; other site
1123863003452	ABC-ATPase subunit interface; other site
1123863003453	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1123863003454	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1123863003455	magnesium-transporting ATPase; Provisional; Region: PRK15122
1123863003456	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1123863003457	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1123863003458	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1123863003459	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863003460	motif II; other site
1123863003461	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1123863003462	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863003463	DNA binding site [nucleotide binding]
1123863003464	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1123863003465	FaeA-like protein; Region: FaeA; pfam04703
1123863003466	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1123863003467	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1123863003468	Walker A/P-loop; other site
1123863003469	ATP binding site [chemical binding]; other site
1123863003470	Q-loop/lid; other site
1123863003471	ABC transporter signature motif; other site
1123863003472	Walker B; other site
1123863003473	D-loop; other site
1123863003474	H-loop/switch region; other site
1123863003475	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1123863003476	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863003477	ABC-ATPase subunit  interface; other site
1123863003478	dimer interface [polypeptide binding]; other site
1123863003479	putative PBP binding regions; other site
1123863003480	Metal binding protein TroA_a.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148
1123863003481	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
1123863003482	putative ligand binding residues [chemical binding]; other site
1123863003483	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1123863003484	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1123863003485	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863003486	dimerization interface [polypeptide binding]; other site
1123863003487	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863003488	dimer interface [polypeptide binding]; other site
1123863003489	phosphorylation site [posttranslational modification]
1123863003490	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863003491	ATP binding site [chemical binding]; other site
1123863003492	Mg2+ binding site [ion binding]; other site
1123863003493	G-X-G motif; other site
1123863003494	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1123863003495	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863003496	active site
1123863003497	phosphorylation site [posttranslational modification]
1123863003498	intermolecular recognition site; other site
1123863003499	dimerization interface [polypeptide binding]; other site
1123863003500	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863003501	DNA binding site [nucleotide binding]
1123863003502	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1123863003503	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1123863003504	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1123863003505	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1123863003506	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1123863003507	trimer interface [polypeptide binding]; other site
1123863003508	eyelet of channel; other site
1123863003509	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1123863003510	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1123863003511	ligand binding site [chemical binding]; other site
1123863003512	NAD binding site [chemical binding]; other site
1123863003513	dimerization interface [polypeptide binding]; other site
1123863003514	catalytic site [active]
1123863003515	hypothetical protein; Validated; Region: PRK06201
1123863003516	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
1123863003517	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1123863003518	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1123863003519	transmembrane helices; other site
1123863003520	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
1123863003521	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1123863003522	active site
1123863003523	Propionate catabolism activator; Region: PrpR_N; pfam06506
1123863003524	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1123863003525	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863003526	Walker A motif; other site
1123863003527	ATP binding site [chemical binding]; other site
1123863003528	Walker B motif; other site
1123863003529	arginine finger; other site
1123863003530	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1123863003531	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863003532	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863003533	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1123863003534	putative effector binding pocket; other site
1123863003535	putative dimerization interface [polypeptide binding]; other site
1123863003536	hypothetical protein; Provisional; Region: PRK09739
1123863003537	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1123863003538	Right handed beta helix region; Region: Beta_helix; pfam13229
1123863003539	Predicted transcriptional regulators [Transcription]; Region: COG1733
1123863003540	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1123863003541	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR7; cd08276
1123863003542	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1123863003543	putative NAD(P) binding site [chemical binding]; other site
1123863003544	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1123863003545	active site
1123863003546	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1123863003547	CAT RNA binding domain; Region: CAT_RBD; smart01061
1123863003548	PRD domain; Region: PRD; pfam00874
1123863003549	PRD domain; Region: PRD; pfam00874
1123863003550	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863003551	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863003552	putative substrate translocation pore; other site
1123863003553	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1123863003554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863003555	putative substrate translocation pore; other site
1123863003556	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
1123863003557	Strictosidine synthase; Region: Str_synth; pfam03088
1123863003558	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1123863003559	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1123863003560	ligand binding site [chemical binding]; other site
1123863003561	NAD binding site [chemical binding]; other site
1123863003562	dimerization interface [polypeptide binding]; other site
1123863003563	catalytic site [active]
1123863003564	hypothetical protein; Validated; Region: PRK06201
1123863003565	Demethylmenaquinone methyltransferase; Region: Methyltransf_6; cl00480
1123863003566	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1123863003567	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1123863003568	Bacterial transcriptional regulator; Region: IclR; pfam01614
1123863003569	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1123863003570	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1123863003571	Walker A/P-loop; other site
1123863003572	ATP binding site [chemical binding]; other site
1123863003573	Q-loop/lid; other site
1123863003574	ABC transporter signature motif; other site
1123863003575	Walker B; other site
1123863003576	D-loop; other site
1123863003577	H-loop/switch region; other site
1123863003578	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863003579	ABC-ATPase subunit  interface; other site
1123863003580	dimer interface [polypeptide binding]; other site
1123863003581	putative PBP binding regions; other site
1123863003582	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1123863003583	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863003584	ABC-ATPase subunit  interface; other site
1123863003585	dimer interface [polypeptide binding]; other site
1123863003586	putative PBP binding regions; other site
1123863003587	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1123863003588	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
1123863003589	putative ligand binding residues [chemical binding]; other site
1123863003590	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
1123863003591	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863003592	N-terminal plug; other site
1123863003593	ligand-binding site [chemical binding]; other site
1123863003594	haloalkane dehalogenase; Provisional; Region: PRK03592
1123863003595	Epoxide hydrolase N terminus; Region: EHN; pfam06441
1123863003596	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1123863003597	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863003598	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1123863003599	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1123863003600	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1123863003601	hypothetical protein; Reviewed; Region: PRK00024
1123863003602	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1123863003603	MPN+ (JAMM) motif; other site
1123863003604	Zinc-binding site [ion binding]; other site
1123863003605	Antirestriction protein; Region: Antirestrict; pfam03230
1123863003606	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1123863003607	SH3 domain-containing protein; Provisional; Region: PRK10884
1123863003608	Predicted transcriptional regulator [Transcription]; Region: COG2378
1123863003609	WYL domain; Region: WYL; pfam13280
1123863003610	Predicted GTPase [General function prediction only]; Region: COG3596
1123863003611	YfjP GTPase; Region: YfjP; cd11383
1123863003612	G1 box; other site
1123863003613	GTP/Mg2+ binding site [chemical binding]; other site
1123863003614	Switch I region; other site
1123863003615	G2 box; other site
1123863003616	Switch II region; other site
1123863003617	G3 box; other site
1123863003618	G4 box; other site
1123863003619	G5 box; other site
1123863003620	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1123863003621	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1123863003622	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1123863003623	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1123863003624	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
1123863003625	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1123863003626	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863003627	AAA domain; Region: AAA_21; pfam13304
1123863003628	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863003629	Walker A/P-loop; other site
1123863003630	Walker A/P-loop; other site
1123863003631	ATP binding site [chemical binding]; other site
1123863003632	ATP binding site [chemical binding]; other site
1123863003633	AAA domain; Region: AAA_21; pfam13304
1123863003634	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1123863003635	ABC transporter signature motif; other site
1123863003636	Walker B; other site
1123863003637	D-loop; other site
1123863003638	H-loop/switch region; other site
1123863003639	potential frameshift: common BLAST hit: gi|237809020|ref|YP_002893460.1| CP4-57 prophage protein
1123863003640	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
1123863003641	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
1123863003642	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1123863003643	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
1123863003644	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863003645	Walker A/P-loop; other site
1123863003646	ATP binding site [chemical binding]; other site
1123863003647	integrase; Provisional; Region: PRK09692
1123863003648	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1123863003649	active site
1123863003650	Int/Topo IB signature motif; other site
1123863003651	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1123863003652	SmpB-tmRNA interface; other site
1123863003653	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1123863003654	putative coenzyme Q binding site [chemical binding]; other site
1123863003655	hypothetical protein; Validated; Region: PRK01777
1123863003656	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1123863003657	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1123863003658	recombination and repair protein; Provisional; Region: PRK10869
1123863003659	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1123863003660	Walker A/P-loop; other site
1123863003661	ATP binding site [chemical binding]; other site
1123863003662	Q-loop/lid; other site
1123863003663	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1123863003664	Q-loop/lid; other site
1123863003665	ABC transporter signature motif; other site
1123863003666	Walker B; other site
1123863003667	D-loop; other site
1123863003668	H-loop/switch region; other site
1123863003669	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1123863003670	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1123863003671	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1123863003672	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1123863003673	dimer interface [polypeptide binding]; other site
1123863003674	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1123863003675	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1123863003676	ligand binding site [chemical binding]; other site
1123863003677	active site
1123863003678	UGI interface [polypeptide binding]; other site
1123863003679	catalytic site [active]
1123863003680	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1123863003681	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1123863003682	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1123863003683	ATP binding site [chemical binding]; other site
1123863003684	Mg++ binding site [ion binding]; other site
1123863003685	motif III; other site
1123863003686	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863003687	nucleotide binding region [chemical binding]; other site
1123863003688	ATP-binding site [chemical binding]; other site
1123863003689	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1123863003690	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863003691	S-adenosylmethionine binding site [chemical binding]; other site
1123863003692	L-aspartate oxidase; Provisional; Region: PRK09077
1123863003693	L-aspartate oxidase; Provisional; Region: PRK06175
1123863003694	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1123863003695	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1123863003696	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863003697	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1123863003698	DNA binding residues [nucleotide binding]
1123863003699	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1123863003700	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1123863003701	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1123863003702	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1123863003703	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1123863003704	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1123863003705	GTP-binding protein LepA; Provisional; Region: PRK05433
1123863003706	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1123863003707	G1 box; other site
1123863003708	putative GEF interaction site [polypeptide binding]; other site
1123863003709	GTP/Mg2+ binding site [chemical binding]; other site
1123863003710	Switch I region; other site
1123863003711	G2 box; other site
1123863003712	G3 box; other site
1123863003713	Switch II region; other site
1123863003714	G4 box; other site
1123863003715	G5 box; other site
1123863003716	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1123863003717	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1123863003718	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1123863003719	signal peptidase I; Provisional; Region: PRK10861
1123863003720	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1123863003721	Catalytic site [active]
1123863003722	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1123863003723	ribonuclease III; Reviewed; Region: rnc; PRK00102
1123863003724	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1123863003725	dimerization interface [polypeptide binding]; other site
1123863003726	active site
1123863003727	metal binding site [ion binding]; metal-binding site
1123863003728	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1123863003729	dsRNA binding site [nucleotide binding]; other site
1123863003730	GTPase Era; Reviewed; Region: era; PRK00089
1123863003731	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1123863003732	G1 box; other site
1123863003733	GTP/Mg2+ binding site [chemical binding]; other site
1123863003734	Switch I region; other site
1123863003735	G2 box; other site
1123863003736	Switch II region; other site
1123863003737	G3 box; other site
1123863003738	G4 box; other site
1123863003739	G5 box; other site
1123863003740	KH domain; Region: KH_2; pfam07650
1123863003741	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1123863003742	Recombination protein O N terminal; Region: RecO_N; pfam11967
1123863003743	Recombination protein O C terminal; Region: RecO_C; pfam02565
1123863003744	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1123863003745	active site
1123863003746	hydrophilic channel; other site
1123863003747	dimerization interface [polypeptide binding]; other site
1123863003748	catalytic residues [active]
1123863003749	active site lid [active]
1123863003750	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1123863003751	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1123863003752	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863003753	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1123863003754	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1123863003755	putative active site [active]
1123863003756	hypothetical protein; Provisional; Region: PRK11590
1123863003757	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1123863003758	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1123863003759	nucleoside/Zn binding site; other site
1123863003760	dimer interface [polypeptide binding]; other site
1123863003761	catalytic motif [active]
1123863003762	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1123863003763	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863003764	substrate binding pocket [chemical binding]; other site
1123863003765	membrane-bound complex binding site; other site
1123863003766	hinge residues; other site
1123863003767	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1123863003768	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1123863003769	catalytic residue [active]
1123863003770	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1123863003771	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1123863003772	dimerization interface [polypeptide binding]; other site
1123863003773	ATP binding site [chemical binding]; other site
1123863003774	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1123863003775	dimerization interface [polypeptide binding]; other site
1123863003776	ATP binding site [chemical binding]; other site
1123863003777	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1123863003778	putative active site [active]
1123863003779	catalytic triad [active]
1123863003780	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1123863003781	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863003782	dimer interface [polypeptide binding]; other site
1123863003783	phosphorylation site [posttranslational modification]
1123863003784	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863003785	ATP binding site [chemical binding]; other site
1123863003786	Mg2+ binding site [ion binding]; other site
1123863003787	G-X-G motif; other site
1123863003788	hypothetical protein; Provisional; Region: PRK10722
1123863003789	response regulator GlrR; Provisional; Region: PRK15115
1123863003790	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863003791	active site
1123863003792	phosphorylation site [posttranslational modification]
1123863003793	intermolecular recognition site; other site
1123863003794	dimerization interface [polypeptide binding]; other site
1123863003795	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863003796	Walker A motif; other site
1123863003797	ATP binding site [chemical binding]; other site
1123863003798	Walker B motif; other site
1123863003799	arginine finger; other site
1123863003800	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1123863003801	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1123863003802	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1123863003803	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1123863003804	heme-binding site [chemical binding]; other site
1123863003805	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1123863003806	FAD binding pocket [chemical binding]; other site
1123863003807	FAD binding motif [chemical binding]; other site
1123863003808	phosphate binding motif [ion binding]; other site
1123863003809	beta-alpha-beta structure motif; other site
1123863003810	NAD binding pocket [chemical binding]; other site
1123863003811	Heme binding  pocket [chemical binding]; other site
1123863003812	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1123863003813	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1123863003814	dimer interface [polypeptide binding]; other site
1123863003815	active site
1123863003816	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1123863003817	folate binding site [chemical binding]; other site
1123863003818	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1123863003819	MFS_1 like family; Region: MFS_1_like; pfam12832
1123863003820	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1123863003821	PRD domain; Region: PRD; pfam00874
1123863003822	Protein of unknown function (DUF1007); Region: DUF1007; pfam06226
1123863003823	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1123863003824	putative membrane protein, TIGR04086 family; Region: TIGR04086_membr
1123863003825	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1123863003826	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1123863003827	active site
1123863003828	dimerization interface [polypeptide binding]; other site
1123863003829	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1123863003830	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1123863003831	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1123863003832	Rrf2 family protein; Region: rrf2_super; TIGR00738
1123863003833	cysteine desulfurase; Provisional; Region: PRK14012
1123863003834	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1123863003835	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863003836	catalytic residue [active]
1123863003837	aminopeptidase B; Provisional; Region: PRK05015
1123863003838	Peptidase; Region: DUF3663; pfam12404
1123863003839	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1123863003840	interface (dimer of trimers) [polypeptide binding]; other site
1123863003841	Substrate-binding/catalytic site; other site
1123863003842	Zn-binding sites [ion binding]; other site
1123863003843	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1123863003844	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1123863003845	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1123863003846	active site residue [active]
1123863003847	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1123863003848	active site residue [active]
1123863003849	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1123863003850	MG2 domain; Region: A2M_N; pfam01835
1123863003851	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1123863003852	surface patch; other site
1123863003853	thioester region; other site
1123863003854	penicillin-binding protein 1C; Provisional; Region: PRK11240
1123863003855	Transglycosylase; Region: Transgly; pfam00912
1123863003856	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1123863003857	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1123863003858	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1123863003859	active site
1123863003860	multimer interface [polypeptide binding]; other site
1123863003861	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1123863003862	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863003863	FeS/SAM binding site; other site
1123863003864	Tfp pilus assembly protein PilF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilF; COG3063
1123863003865	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1123863003866	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863003867	non-specific DNA binding site [nucleotide binding]; other site
1123863003868	salt bridge; other site
1123863003869	sequence-specific DNA binding site [nucleotide binding]; other site
1123863003870	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1123863003871	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1123863003872	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1123863003873	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1123863003874	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1123863003875	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1123863003876	dimer interface [polypeptide binding]; other site
1123863003877	motif 1; other site
1123863003878	active site
1123863003879	motif 2; other site
1123863003880	motif 3; other site
1123863003881	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1123863003882	anticodon binding site; other site
1123863003883	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1123863003884	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1123863003885	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1123863003886	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1123863003887	Trp docking motif [polypeptide binding]; other site
1123863003888	GTP-binding protein Der; Reviewed; Region: PRK00093
1123863003889	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1123863003890	G1 box; other site
1123863003891	GTP/Mg2+ binding site [chemical binding]; other site
1123863003892	Switch I region; other site
1123863003893	G2 box; other site
1123863003894	Switch II region; other site
1123863003895	G3 box; other site
1123863003896	G4 box; other site
1123863003897	G5 box; other site
1123863003898	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1123863003899	G1 box; other site
1123863003900	GTP/Mg2+ binding site [chemical binding]; other site
1123863003901	Switch I region; other site
1123863003902	G2 box; other site
1123863003903	G3 box; other site
1123863003904	Switch II region; other site
1123863003905	G4 box; other site
1123863003906	G5 box; other site
1123863003907	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1123863003908	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1123863003909	Trp docking motif [polypeptide binding]; other site
1123863003910	putative active site [active]
1123863003911	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1123863003912	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1123863003913	active site
1123863003914	Zn binding site [ion binding]; other site
1123863003915	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1123863003916	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1123863003917	generic binding surface II; other site
1123863003918	generic binding surface I; other site
1123863003919	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1123863003920	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1123863003921	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1123863003922	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1123863003923	active site
1123863003924	GMP synthase; Reviewed; Region: guaA; PRK00074
1123863003925	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1123863003926	AMP/PPi binding site [chemical binding]; other site
1123863003927	candidate oxyanion hole; other site
1123863003928	catalytic triad [active]
1123863003929	potential glutamine specificity residues [chemical binding]; other site
1123863003930	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1123863003931	ATP Binding subdomain [chemical binding]; other site
1123863003932	Ligand Binding sites [chemical binding]; other site
1123863003933	Dimerization subdomain; other site
1123863003934	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1123863003935	EamA-like transporter family; Region: EamA; pfam00892
1123863003936	EamA-like transporter family; Region: EamA; pfam00892
1123863003937	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1123863003938	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1123863003939	substrate binding pocket [chemical binding]; other site
1123863003940	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1123863003941	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1123863003942	TPR motif; other site
1123863003943	binding surface
1123863003944	Protein of unknown function (DUF3750); Region: DUF3750; pfam12570
1123863003945	Uncharacterized small protein (DUF2158); Region: DUF2158; cl02293
1123863003946	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1123863003947	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1123863003948	MgtE intracellular N domain; Region: MgtE_N; smart00924
1123863003949	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1123863003950	Divalent cation transporter; Region: MgtE; cl00786
1123863003951	tellurite resistance protein TehB; Provisional; Region: PRK11207
1123863003952	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863003953	S-adenosylmethionine binding site [chemical binding]; other site
1123863003954	exopolyphosphatase; Provisional; Region: PRK10854
1123863003955	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1123863003956	nucleotide binding site [chemical binding]; other site
1123863003957	polyphosphate kinase; Provisional; Region: PRK05443
1123863003958	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1123863003959	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1123863003960	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
1123863003961	domain interface [polypeptide binding]; other site
1123863003962	active site
1123863003963	catalytic site [active]
1123863003964	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1123863003965	domain interface [polypeptide binding]; other site
1123863003966	active site
1123863003967	catalytic site [active]
1123863003968	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4590
1123863003969	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863003970	ABC-ATPase subunit interface; other site
1123863003971	ABC-type phosphate transport system, auxiliary component [Inorganic ion transport and metabolism]; Region: COG4985
1123863003972	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1123863003973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863003974	ABC-ATPase subunit interface; other site
1123863003975	phosphate transporter ATP-binding protein; Provisional; Region: PRK14236
1123863003976	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1123863003977	Walker A/P-loop; other site
1123863003978	ATP binding site [chemical binding]; other site
1123863003979	Q-loop/lid; other site
1123863003980	ABC transporter signature motif; other site
1123863003981	Walker B; other site
1123863003982	D-loop; other site
1123863003983	H-loop/switch region; other site
1123863003984	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1123863003985	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1123863003986	active site
1123863003987	substrate binding site [chemical binding]; other site
1123863003988	cosubstrate binding site; other site
1123863003989	catalytic site [active]
1123863003990	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1123863003991	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1123863003992	dimerization interface [polypeptide binding]; other site
1123863003993	putative ATP binding site [chemical binding]; other site
1123863003994	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1123863003995	active site
1123863003996	uracil transporter; Provisional; Region: PRK10720
1123863003997	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1123863003998	DNA replication initiation factor; Provisional; Region: PRK08084
1123863003999	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1123863004000	ArsC family; Region: ArsC; pfam03960
1123863004001	catalytic residues [active]
1123863004002	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1123863004003	Peptidase family M48; Region: Peptidase_M48; pfam01435
1123863004004	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863004005	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863004006	DNA binding site [nucleotide binding]
1123863004007	domain linker motif; other site
1123863004008	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1123863004009	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1123863004010	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1123863004011	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1123863004012	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004013	dimer interface [polypeptide binding]; other site
1123863004014	conserved gate region; other site
1123863004015	putative PBP binding loops; other site
1123863004016	ABC-ATPase subunit interface; other site
1123863004017	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1123863004018	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004019	dimer interface [polypeptide binding]; other site
1123863004020	conserved gate region; other site
1123863004021	putative PBP binding loops; other site
1123863004022	ABC-ATPase subunit interface; other site
1123863004023	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1123863004024	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863004025	Walker A/P-loop; other site
1123863004026	ATP binding site [chemical binding]; other site
1123863004027	Q-loop/lid; other site
1123863004028	ABC transporter signature motif; other site
1123863004029	Walker B; other site
1123863004030	D-loop; other site
1123863004031	H-loop/switch region; other site
1123863004032	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1123863004033	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1123863004034	active site
1123863004035	metal binding site [ion binding]; metal-binding site
1123863004036	hexamer interface [polypeptide binding]; other site
1123863004037	Cache domain; Region: Cache_1; pfam02743
1123863004038	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863004039	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863004040	metal binding site [ion binding]; metal-binding site
1123863004041	active site
1123863004042	I-site; other site
1123863004043	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1123863004044	Helix-turn-helix domain; Region: HTH_18; pfam12833
1123863004045	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863004046	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1123863004047	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1123863004048	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1123863004049	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1123863004050	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1123863004051	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1123863004052	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1123863004053	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1123863004054	catalytic triad [active]
1123863004055	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1123863004056	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1123863004057	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1123863004058	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1123863004059	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1123863004060	dimer interface [polypeptide binding]; other site
1123863004061	active site
1123863004062	catalytic residue [active]
1123863004063	lipoprotein; Provisional; Region: PRK11679
1123863004064	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1123863004065	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1123863004066	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1123863004067	ATP binding site [chemical binding]; other site
1123863004068	active site
1123863004069	substrate binding site [chemical binding]; other site
1123863004070	Predicted metalloprotease [General function prediction only]; Region: COG2321
1123863004071	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1123863004072	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1123863004073	Helicase; Region: Helicase_RecD; pfam05127
1123863004074	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1123863004075	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1123863004076	putative hydrolase; Provisional; Region: PRK11460
1123863004077	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
1123863004078	hypothetical protein; Provisional; Region: PRK13664
1123863004079	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1123863004080	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1123863004081	metal binding site [ion binding]; metal-binding site
1123863004082	dimer interface [polypeptide binding]; other site
1123863004083	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1123863004084	ArsC family; Region: ArsC; pfam03960
1123863004085	putative catalytic residues [active]
1123863004086	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1123863004087	Protein export membrane protein; Region: SecD_SecF; cl14618
1123863004088	transcriptional regulator NarP; Provisional; Region: PRK10403
1123863004089	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863004090	active site
1123863004091	phosphorylation site [posttranslational modification]
1123863004092	intermolecular recognition site; other site
1123863004093	dimerization interface [polypeptide binding]; other site
1123863004094	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1123863004095	DNA binding residues [nucleotide binding]
1123863004096	dimerization interface [polypeptide binding]; other site
1123863004097	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1123863004098	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1123863004099	HAMP domain; Region: HAMP; pfam00672
1123863004100	Histidine kinase; Region: HisKA_3; pfam07730
1123863004101	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863004102	ATP binding site [chemical binding]; other site
1123863004103	Mg2+ binding site [ion binding]; other site
1123863004104	G-X-G motif; other site
1123863004105	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863004106	L-asparagine permease; Provisional; Region: PRK15049
1123863004107	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1123863004108	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1123863004109	dimer interface [polypeptide binding]; other site
1123863004110	ADP-ribose binding site [chemical binding]; other site
1123863004111	active site
1123863004112	nudix motif; other site
1123863004113	metal binding site [ion binding]; metal-binding site
1123863004114	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863004115	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1123863004116	substrate binding site [chemical binding]; other site
1123863004117	dimer interface [polypeptide binding]; other site
1123863004118	ATP binding site [chemical binding]; other site
1123863004119	D-allose kinase; Provisional; Region: PRK09698
1123863004120	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1123863004121	nucleotide binding site [chemical binding]; other site
1123863004122	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1123863004123	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1123863004124	substrate binding site [chemical binding]; other site
1123863004125	hexamer interface [polypeptide binding]; other site
1123863004126	metal binding site [ion binding]; metal-binding site
1123863004127	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863004128	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863004129	TM-ABC transporter signature motif; other site
1123863004130	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863004131	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863004132	TM-ABC transporter signature motif; other site
1123863004133	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863004134	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863004135	Walker A/P-loop; other site
1123863004136	ATP binding site [chemical binding]; other site
1123863004137	Q-loop/lid; other site
1123863004138	ABC transporter signature motif; other site
1123863004139	Walker B; other site
1123863004140	D-loop; other site
1123863004141	H-loop/switch region; other site
1123863004142	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863004143	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1123863004144	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1123863004145	ligand binding site [chemical binding]; other site
1123863004146	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1123863004147	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1123863004148	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863004149	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1123863004150	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1123863004151	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1123863004152	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1123863004153	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863004154	active site
1123863004155	phosphorylation site [posttranslational modification]
1123863004156	intermolecular recognition site; other site
1123863004157	dimerization interface [polypeptide binding]; other site
1123863004158	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1123863004159	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863004160	putative active site [active]
1123863004161	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863004162	ATP binding site [chemical binding]; other site
1123863004163	Mg2+ binding site [ion binding]; other site
1123863004164	G-X-G motif; other site
1123863004165	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1123863004166	transketolase; Reviewed; Region: PRK12753
1123863004167	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1123863004168	TPP-binding site [chemical binding]; other site
1123863004169	dimer interface [polypeptide binding]; other site
1123863004170	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1123863004171	PYR/PP interface [polypeptide binding]; other site
1123863004172	dimer interface [polypeptide binding]; other site
1123863004173	TPP binding site [chemical binding]; other site
1123863004174	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1123863004175	transaldolase-like protein; Provisional; Region: PTZ00411
1123863004176	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1123863004177	active site
1123863004178	dimer interface [polypeptide binding]; other site
1123863004179	catalytic residue [active]
1123863004180	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1123863004181	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1123863004182	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1123863004183	putative NAD(P) binding site [chemical binding]; other site
1123863004184	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1123863004185	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1123863004186	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1123863004187	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1123863004188	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1123863004189	active site
1123863004190	metal binding site [ion binding]; metal-binding site
1123863004191	putative acetyltransferase; Provisional; Region: PRK03624
1123863004192	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863004193	Coenzyme A binding pocket [chemical binding]; other site
1123863004194	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1123863004195	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1123863004196	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1123863004197	thiosulfate transporter subunit; Provisional; Region: PRK10852
1123863004198	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1123863004199	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1123863004200	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004201	dimer interface [polypeptide binding]; other site
1123863004202	conserved gate region; other site
1123863004203	putative PBP binding loops; other site
1123863004204	ABC-ATPase subunit interface; other site
1123863004205	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
1123863004206	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004207	dimer interface [polypeptide binding]; other site
1123863004208	conserved gate region; other site
1123863004209	putative PBP binding loops; other site
1123863004210	ABC-ATPase subunit interface; other site
1123863004211	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1123863004212	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1123863004213	Walker A/P-loop; other site
1123863004214	ATP binding site [chemical binding]; other site
1123863004215	Q-loop/lid; other site
1123863004216	ABC transporter signature motif; other site
1123863004217	Walker B; other site
1123863004218	D-loop; other site
1123863004219	H-loop/switch region; other site
1123863004220	TOBE-like domain; Region: TOBE_3; pfam12857
1123863004221	cysteine synthase B; Region: cysM; TIGR01138
1123863004222	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1123863004223	dimer interface [polypeptide binding]; other site
1123863004224	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863004225	catalytic residue [active]
1123863004226	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1123863004227	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863004228	active site
1123863004229	phosphorylation site [posttranslational modification]
1123863004230	intermolecular recognition site; other site
1123863004231	dimerization interface [polypeptide binding]; other site
1123863004232	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863004233	DNA binding site [nucleotide binding]
1123863004234	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863004235	dimerization interface [polypeptide binding]; other site
1123863004236	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863004237	dimer interface [polypeptide binding]; other site
1123863004238	phosphorylation site [posttranslational modification]
1123863004239	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863004240	ATP binding site [chemical binding]; other site
1123863004241	Mg2+ binding site [ion binding]; other site
1123863004242	G-X-G motif; other site
1123863004243	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1123863004244	HPr interaction site; other site
1123863004245	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1123863004246	active site
1123863004247	phosphorylation site [posttranslational modification]
1123863004248	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1123863004249	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1123863004250	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1123863004251	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1123863004252	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1123863004253	dimerization domain swap beta strand [polypeptide binding]; other site
1123863004254	regulatory protein interface [polypeptide binding]; other site
1123863004255	active site
1123863004256	regulatory phosphorylation site [posttranslational modification]; other site
1123863004257	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1123863004258	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1123863004259	dimer interface [polypeptide binding]; other site
1123863004260	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863004261	catalytic residue [active]
1123863004262	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1123863004263	cell division protein ZipA; Provisional; Region: PRK03427
1123863004264	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1123863004265	FtsZ protein binding site [polypeptide binding]; other site
1123863004266	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1123863004267	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1123863004268	nucleotide binding pocket [chemical binding]; other site
1123863004269	K-X-D-G motif; other site
1123863004270	catalytic site [active]
1123863004271	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1123863004272	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1123863004273	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1123863004274	Dimer interface [polypeptide binding]; other site
1123863004275	BRCT sequence motif; other site
1123863004276	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
1123863004277	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1123863004278	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1123863004279	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863004280	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863004281	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1123863004282	putative dimerization interface [polypeptide binding]; other site
1123863004283	potential protein location (hypothetical protein PANA5342_1295 [Pantoea ananatis LMG 5342]) that overlaps RNA (tRNA-K)
1123863004284	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1123863004285	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1123863004286	active site
1123863004287	HIGH motif; other site
1123863004288	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1123863004289	active site
1123863004290	KMSKS motif; other site
1123863004291	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1123863004292	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1123863004293	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1123863004294	active site
1123863004295	NTP binding site [chemical binding]; other site
1123863004296	metal binding triad [ion binding]; metal-binding site
1123863004297	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1123863004298	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1123863004299	Nucleoside recognition; Region: Gate; pfam07670
1123863004300	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1123863004301	manganese transport protein MntH; Reviewed; Region: PRK00701
1123863004302	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1123863004303	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1123863004304	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863004305	S-adenosylmethionine binding site [chemical binding]; other site
1123863004306	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1123863004307	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1123863004308	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1123863004309	active site
1123863004310	catalytic tetrad [active]
1123863004311	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1123863004312	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1123863004313	dimer interface [polypeptide binding]; other site
1123863004314	PYR/PP interface [polypeptide binding]; other site
1123863004315	TPP binding site [chemical binding]; other site
1123863004316	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1123863004317	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1123863004318	TPP-binding site [chemical binding]; other site
1123863004319	dimer interface [polypeptide binding]; other site
1123863004320	glucokinase, proteobacterial type; Region: glk; TIGR00749
1123863004321	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1123863004322	nucleotide binding site [chemical binding]; other site
1123863004323	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1123863004324	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863004325	active site
1123863004326	phosphorylation site [posttranslational modification]
1123863004327	intermolecular recognition site; other site
1123863004328	dimerization interface [polypeptide binding]; other site
1123863004329	LytTr DNA-binding domain; Region: LytTR; pfam04397
1123863004330	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1123863004331	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1123863004332	GAF domain; Region: GAF_3; pfam13492
1123863004333	Histidine kinase; Region: His_kinase; pfam06580
1123863004334	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863004335	ATP binding site [chemical binding]; other site
1123863004336	Mg2+ binding site [ion binding]; other site
1123863004337	G-X-G motif; other site
1123863004338	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1123863004339	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863004340	Coenzyme A binding pocket [chemical binding]; other site
1123863004341	aminotransferase; Validated; Region: PRK08175
1123863004342	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863004343	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863004344	homodimer interface [polypeptide binding]; other site
1123863004345	catalytic residue [active]
1123863004346	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1123863004347	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863004348	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863004349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863004350	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863004351	putative substrate translocation pore; other site
1123863004352	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1123863004353	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1123863004354	Bacterial transcriptional regulator; Region: IclR; pfam01614
1123863004355	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1123863004356	Ligand Binding Site [chemical binding]; other site
1123863004357	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1123863004358	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1123863004359	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863004360	putative substrate translocation pore; other site
1123863004361	Secretin and TonB N terminus short domain; Region: STN; smart00965
1123863004362	RES domain; Region: RES; pfam08808
1123863004363	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1123863004364	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1123863004365	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1123863004366	PapC N-terminal domain; Region: PapC_N; pfam13954
1123863004367	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1123863004368	PapC C-terminal domain; Region: PapC_C; pfam13953
1123863004369	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1123863004370	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863004371	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1123863004372	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1123863004373	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1123863004374	FaeA-like protein; Region: FaeA; pfam04703
1123863004375	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1123863004376	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863004377	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1123863004378	Fimbrial protein; Region: Fimbrial; pfam00419
1123863004379	Fimbrial protein; Region: Fimbrial; pfam00419
1123863004380	Fimbrial protein; Region: Fimbrial; cl01416
1123863004381	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1123863004382	MarR family; Region: MarR_2; pfam12802
1123863004383	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1123863004384	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1123863004385	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
1123863004386	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1123863004387	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004388	dimer interface [polypeptide binding]; other site
1123863004389	conserved gate region; other site
1123863004390	putative PBP binding loops; other site
1123863004391	ABC-ATPase subunit interface; other site
1123863004392	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1123863004393	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004394	dimer interface [polypeptide binding]; other site
1123863004395	conserved gate region; other site
1123863004396	putative PBP binding loops; other site
1123863004397	ABC-ATPase subunit interface; other site
1123863004398	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1123863004399	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863004400	Walker A/P-loop; other site
1123863004401	ATP binding site [chemical binding]; other site
1123863004402	Q-loop/lid; other site
1123863004403	ABC transporter signature motif; other site
1123863004404	Walker B; other site
1123863004405	D-loop; other site
1123863004406	H-loop/switch region; other site
1123863004407	TOBE domain; Region: TOBE_2; pfam08402
1123863004408	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1123863004409	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
1123863004410	putative active site [active]
1123863004411	catalytic site [active]
1123863004412	putative metal binding site [ion binding]; other site
1123863004413	oligomer interface [polypeptide binding]; other site
1123863004414	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
1123863004415	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1123863004416	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1123863004417	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
1123863004418	Walker A/P-loop; other site
1123863004419	ATP binding site [chemical binding]; other site
1123863004420	Q-loop/lid; other site
1123863004421	ABC transporter signature motif; other site
1123863004422	Walker B; other site
1123863004423	D-loop; other site
1123863004424	H-loop/switch region; other site
1123863004425	heme exporter protein CcmB; Region: ccmB; TIGR01190
1123863004426	heme exporter protein CcmC; Region: ccmC; TIGR01191
1123863004427	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1123863004428	CcmE; Region: CcmE; cl00994
1123863004429	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1123863004430	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1123863004431	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1123863004432	catalytic residues [active]
1123863004433	central insert; other site
1123863004434	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
1123863004435	cytochrome c-type biogenesis protein CcmI; Region: cytochro_ccmI; TIGR03142
1123863004436	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1123863004437	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1123863004438	binding surface
1123863004439	TPR motif; other site
1123863004440	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1123863004441	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1123863004442	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1123863004443	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1123863004444	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1123863004445	dimer interface [polypeptide binding]; other site
1123863004446	active site
1123863004447	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1123863004448	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1123863004449	substrate binding site [chemical binding]; other site
1123863004450	oxyanion hole (OAH) forming residues; other site
1123863004451	trimer interface [polypeptide binding]; other site
1123863004452	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1123863004453	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1123863004454	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1123863004455	catalytic core [active]
1123863004456	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863004457	dimerization interface [polypeptide binding]; other site
1123863004458	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863004459	dimer interface [polypeptide binding]; other site
1123863004460	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1123863004461	putative CheW interface [polypeptide binding]; other site
1123863004462	hypothetical protein; Provisional; Region: PRK04946
1123863004463	Smr domain; Region: Smr; pfam01713
1123863004464	HemK family putative methylases; Region: hemK_fam; TIGR00536
1123863004465	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863004466	S-adenosylmethionine binding site [chemical binding]; other site
1123863004467	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1123863004468	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1123863004469	Tetramer interface [polypeptide binding]; other site
1123863004470	active site
1123863004471	FMN-binding site [chemical binding]; other site
1123863004472	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1123863004473	hypothetical protein; Provisional; Region: PRK10621
1123863004474	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1123863004475	Protein of unknown function, DUF462; Region: DUF462; cl01190
1123863004476	YfcL protein; Region: YfcL; pfam08891
1123863004477	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1123863004478	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1123863004479	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1123863004480	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1123863004481	dimer interface [polypeptide binding]; other site
1123863004482	active site
1123863004483	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1123863004484	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863004485	DNA-binding site [nucleotide binding]; DNA binding site
1123863004486	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863004487	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863004488	homodimer interface [polypeptide binding]; other site
1123863004489	catalytic residue [active]
1123863004490	Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins; Region: RHOD_PspE2; cd01521
1123863004491	active site residue [active]
1123863004492	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1123863004493	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1123863004494	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1123863004495	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1123863004496	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1123863004497	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863004498	active site
1123863004499	phosphorylation site [posttranslational modification]
1123863004500	intermolecular recognition site; other site
1123863004501	dimerization interface [polypeptide binding]; other site
1123863004502	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863004503	DNA binding site [nucleotide binding]
1123863004504	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1123863004505	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1123863004506	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863004507	dimer interface [polypeptide binding]; other site
1123863004508	phosphorylation site [posttranslational modification]
1123863004509	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863004510	ATP binding site [chemical binding]; other site
1123863004511	Mg2+ binding site [ion binding]; other site
1123863004512	G-X-G motif; other site
1123863004513	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1123863004514	EamA-like transporter family; Region: EamA; pfam00892
1123863004515	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1123863004516	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1123863004517	ligand binding site [chemical binding]; other site
1123863004518	NAD binding site [chemical binding]; other site
1123863004519	catalytic site [active]
1123863004520	homodimer interface [polypeptide binding]; other site
1123863004521	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1123863004522	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1123863004523	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1123863004524	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1123863004525	dimerization interface 3.5A [polypeptide binding]; other site
1123863004526	active site
1123863004527	hypothetical protein; Provisional; Region: PRK10847
1123863004528	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1123863004529	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1123863004530	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1123863004531	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1123863004532	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1123863004533	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1123863004534	cell division protein DedD; Provisional; Region: PRK11633
1123863004535	Sporulation related domain; Region: SPOR; pfam05036
1123863004536	colicin V production protein; Provisional; Region: PRK10845
1123863004537	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1123863004538	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1123863004539	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1123863004540	active site
1123863004541	tetramer interface [polypeptide binding]; other site
1123863004542	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1123863004543	active site
1123863004544	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1123863004545	Flavoprotein; Region: Flavoprotein; pfam02441
1123863004546	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1123863004547	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863004548	substrate binding pocket [chemical binding]; other site
1123863004549	membrane-bound complex binding site; other site
1123863004550	hinge residues; other site
1123863004551	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863004552	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004553	dimer interface [polypeptide binding]; other site
1123863004554	conserved gate region; other site
1123863004555	putative PBP binding loops; other site
1123863004556	ABC-ATPase subunit interface; other site
1123863004557	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863004558	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004559	dimer interface [polypeptide binding]; other site
1123863004560	conserved gate region; other site
1123863004561	putative PBP binding loops; other site
1123863004562	ABC-ATPase subunit interface; other site
1123863004563	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1123863004564	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863004565	Walker A/P-loop; other site
1123863004566	ATP binding site [chemical binding]; other site
1123863004567	Q-loop/lid; other site
1123863004568	ABC transporter signature motif; other site
1123863004569	Walker B; other site
1123863004570	D-loop; other site
1123863004571	H-loop/switch region; other site
1123863004572	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1123863004573	Helix-turn-helix XRE-family like proteins; Region: HTH_XRE; smart00530
1123863004574	sequence-specific DNA binding site [nucleotide binding]; other site
1123863004575	salt bridge; other site
1123863004576	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1123863004577	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1123863004578	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1123863004579	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1123863004580	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1123863004581	N- and C-terminal domain interface [polypeptide binding]; other site
1123863004582	D-xylulose kinase; Region: XylB; TIGR01312
1123863004583	active site
1123863004584	MgATP binding site [chemical binding]; other site
1123863004585	catalytic site [active]
1123863004586	metal binding site [ion binding]; metal-binding site
1123863004587	xylulose binding site [chemical binding]; other site
1123863004588	homodimer interface [polypeptide binding]; other site
1123863004589	polyol permease family; Region: 2A0118; TIGR00897
1123863004590	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863004591	putative substrate translocation pore; other site
1123863004592	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1123863004593	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1123863004594	putative NAD(P) binding site [chemical binding]; other site
1123863004595	putative active site [active]
1123863004596	glutathione S-transferase; Provisional; Region: PRK15113
1123863004597	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1123863004598	C-terminal domain interface [polypeptide binding]; other site
1123863004599	GSH binding site (G-site) [chemical binding]; other site
1123863004600	dimer interface [polypeptide binding]; other site
1123863004601	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1123863004602	N-terminal domain interface [polypeptide binding]; other site
1123863004603	putative dimer interface [polypeptide binding]; other site
1123863004604	putative substrate binding pocket (H-site) [chemical binding]; other site
1123863004605	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1123863004606	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1123863004607	nudix motif; other site
1123863004608	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1123863004609	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004610	dimer interface [polypeptide binding]; other site
1123863004611	conserved gate region; other site
1123863004612	putative PBP binding loops; other site
1123863004613	ABC-ATPase subunit interface; other site
1123863004614	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004615	dimer interface [polypeptide binding]; other site
1123863004616	conserved gate region; other site
1123863004617	putative PBP binding loops; other site
1123863004618	ABC-ATPase subunit interface; other site
1123863004619	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1123863004620	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1123863004621	4-aminobutyrate aminotransferase; Provisional; Region: PRK06777
1123863004622	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863004623	inhibitor-cofactor binding pocket; inhibition site
1123863004624	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863004625	catalytic residue [active]
1123863004626	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1123863004627	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863004628	DNA-binding site [nucleotide binding]; DNA binding site
1123863004629	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863004630	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863004631	homodimer interface [polypeptide binding]; other site
1123863004632	catalytic residue [active]
1123863004633	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1123863004634	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1123863004635	Walker A/P-loop; other site
1123863004636	ATP binding site [chemical binding]; other site
1123863004637	Q-loop/lid; other site
1123863004638	ABC transporter signature motif; other site
1123863004639	Walker B; other site
1123863004640	D-loop; other site
1123863004641	H-loop/switch region; other site
1123863004642	TOBE domain; Region: TOBE_2; pfam08402
1123863004643	phosphate acetyltransferase; Reviewed; Region: PRK05632
1123863004644	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1123863004645	DRTGG domain; Region: DRTGG; pfam07085
1123863004646	phosphate acetyltransferase; Region: pta; TIGR00651
1123863004647	propionate/acetate kinase; Provisional; Region: PRK12379
1123863004648	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1123863004649	hypothetical protein; Provisional; Region: PRK01816
1123863004650	hypothetical protein; Validated; Region: PRK05445
1123863004651	putative phosphatase; Provisional; Region: PRK11587
1123863004652	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863004653	motif II; other site
1123863004654	5'-nucleotidase; Provisional; Region: PRK03826
1123863004655	aminotransferase AlaT; Validated; Region: PRK09265
1123863004656	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863004657	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863004658	homodimer interface [polypeptide binding]; other site
1123863004659	catalytic residue [active]
1123863004660	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1123863004661	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863004662	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1123863004663	putative dimerization interface [polypeptide binding]; other site
1123863004664	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1123863004665	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1123863004666	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1123863004667	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1123863004668	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1123863004669	NADH:ubiquinone oxidoreductase 24 kD subunit [Energy production and conversion]; Region: NuoE; COG1905
1123863004670	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1123863004671	putative dimer interface [polypeptide binding]; other site
1123863004672	[2Fe-2S] cluster binding site [ion binding]; other site
1123863004673	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1123863004674	SLBB domain; Region: SLBB; pfam10531
1123863004675	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1123863004676	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1123863004677	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1123863004678	catalytic loop [active]
1123863004679	iron binding site [ion binding]; other site
1123863004680	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1123863004681	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1123863004682	[4Fe-4S] binding site [ion binding]; other site
1123863004683	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1123863004684	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1123863004685	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1123863004686	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1123863004687	4Fe-4S binding domain; Region: Fer4; pfam00037
1123863004688	4Fe-4S binding domain; Region: Fer4; pfam00037
1123863004689	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
1123863004690	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1123863004691	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1123863004692	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1123863004693	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1123863004694	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1123863004695	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1123863004696	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1123863004697	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1123863004698	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1123863004699	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
1123863004700	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1123863004701	Predicted acyltransferase [General function prediction only]; Region: ElaA; COG2153
1123863004702	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1123863004703	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1123863004704	hypothetical protein; Provisional; Region: PRK10404
1123863004705	hypothetical protein; Provisional; Region: PRK03673
1123863004706	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1123863004707	putative MPT binding site; other site
1123863004708	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1123863004709	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1123863004710	catalytic loop [active]
1123863004711	iron binding site [ion binding]; other site
1123863004712	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1123863004713	dimer interface [polypeptide binding]; other site
1123863004714	putative radical transfer pathway; other site
1123863004715	diiron center [ion binding]; other site
1123863004716	tyrosyl radical; other site
1123863004717	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1123863004718	ATP cone domain; Region: ATP-cone; pfam03477
1123863004719	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1123863004720	active site
1123863004721	dimer interface [polypeptide binding]; other site
1123863004722	catalytic residues [active]
1123863004723	effector binding site; other site
1123863004724	R2 peptide binding site; other site
1123863004725	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1123863004726	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863004727	S-adenosylmethionine binding site [chemical binding]; other site
1123863004728	DNA gyrase subunit A; Validated; Region: PRK05560
1123863004729	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1123863004730	CAP-like domain; other site
1123863004731	active site
1123863004732	primary dimer interface [polypeptide binding]; other site
1123863004733	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1123863004734	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1123863004735	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1123863004736	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1123863004737	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1123863004738	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1123863004739	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1123863004740	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863004741	dimer interface [polypeptide binding]; other site
1123863004742	phosphorylation site [posttranslational modification]
1123863004743	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863004744	ATP binding site [chemical binding]; other site
1123863004745	Mg2+ binding site [ion binding]; other site
1123863004746	G-X-G motif; other site
1123863004747	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1123863004748	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863004749	active site
1123863004750	phosphorylation site [posttranslational modification]
1123863004751	intermolecular recognition site; other site
1123863004752	dimerization interface [polypeptide binding]; other site
1123863004753	transcriptional regulator RcsB; Provisional; Region: PRK10840
1123863004754	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863004755	active site
1123863004756	phosphorylation site [posttranslational modification]
1123863004757	intermolecular recognition site; other site
1123863004758	dimerization interface [polypeptide binding]; other site
1123863004759	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1123863004760	DNA binding residues [nucleotide binding]
1123863004761	dimerization interface [polypeptide binding]; other site
1123863004762	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1123863004763	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863004764	ATP binding site [chemical binding]; other site
1123863004765	Mg2+ binding site [ion binding]; other site
1123863004766	G-X-G motif; other site
1123863004767	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1123863004768	putative binding surface; other site
1123863004769	active site
1123863004770	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1123863004771	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004772	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004773	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004774	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1123863004775	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1123863004776	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004777	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004778	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004779	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1123863004780	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004781	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1123863004782	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1123863004783	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004784	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1123863004785	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004786	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004787	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1123863004788	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1123863004789	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1123863004790	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1123863004791	ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245
1123863004792	Walker A/P-loop; other site
1123863004793	ATP binding site [chemical binding]; other site
1123863004794	Q-loop/lid; other site
1123863004795	ABC transporter signature motif; other site
1123863004796	Walker B; other site
1123863004797	D-loop; other site
1123863004798	H-loop/switch region; other site
1123863004799	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1123863004800	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863004801	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863004802	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1123863004803	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1123863004804	trimer interface [polypeptide binding]; other site
1123863004805	eyelet of channel; other site
1123863004806	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1123863004807	ApbE family; Region: ApbE; pfam02424
1123863004808	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1123863004809	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1123863004810	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1123863004811	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1123863004812	Walker A/P-loop; other site
1123863004813	ATP binding site [chemical binding]; other site
1123863004814	Q-loop/lid; other site
1123863004815	ABC transporter signature motif; other site
1123863004816	Walker B; other site
1123863004817	D-loop; other site
1123863004818	H-loop/switch region; other site
1123863004819	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1123863004820	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1123863004821	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1123863004822	MFS/sugar transport protein; Region: MFS_2; pfam13347
1123863004823	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
1123863004824	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
1123863004825	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1123863004826	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1123863004827	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
1123863004828	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1123863004829	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1123863004830	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
1123863004831	FecR protein; Region: FecR; pfam04773
1123863004832	RNA polymerase sigma factor; Provisional; Region: PRK12525
1123863004833	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863004834	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1123863004835	DNA binding residues [nucleotide binding]
1123863004836	Secretin and TonB N terminus short domain; Region: STN; smart00965
1123863004837	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1123863004838	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863004839	N-terminal plug; other site
1123863004840	ligand-binding site [chemical binding]; other site
1123863004841	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
1123863004842	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1123863004843	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
1123863004844	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1123863004845	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1123863004846	catalytic residues [active]
1123863004847	peptidase PmbA; Provisional; Region: PRK11040
1123863004848	protease TldD; Provisional; Region: tldD; PRK10735
1123863004849	Protein of unknown function (DUF2891); Region: DUF2891; pfam11199
1123863004850	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4688
1123863004851	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1123863004852	active site
1123863004853	catalytic residues [active]
1123863004854	DNA binding site [nucleotide binding]
1123863004855	Int/Topo IB signature motif; other site
1123863004856	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1123863004857	active site
1123863004858	catalytic residues [active]
1123863004859	DNA binding site [nucleotide binding]
1123863004860	Int/Topo IB signature motif; other site
1123863004861	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
1123863004862	AAA ATPase domain; Region: AAA_15; pfam13175
1123863004863	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863004864	Walker A/P-loop; other site
1123863004865	ATP binding site [chemical binding]; other site
1123863004866	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1123863004867	putative active site [active]
1123863004868	putative metal-binding site [ion binding]; other site
1123863004869	Part of AAA domain; Region: AAA_19; pfam13245
1123863004870	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1123863004871	Family description; Region: UvrD_C_2; pfam13538
1123863004872	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
1123863004873	integrase; Provisional; Region: PRK09692
1123863004874	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1123863004875	active site
1123863004876	Int/Topo IB signature motif; other site
1123863004877	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1123863004878	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1123863004879	Sulfatase; Region: Sulfatase; cl17466
1123863004880	hypothetical protein; Provisional; Region: PRK13689
1123863004881	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1123863004882	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1123863004883	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1123863004884	5S rRNA interface [nucleotide binding]; other site
1123863004885	CTC domain interface [polypeptide binding]; other site
1123863004886	L16 interface [polypeptide binding]; other site
1123863004887	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1123863004888	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863004889	ATP binding site [chemical binding]; other site
1123863004890	putative Mg++ binding site [ion binding]; other site
1123863004891	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863004892	nucleotide binding region [chemical binding]; other site
1123863004893	ATP-binding site [chemical binding]; other site
1123863004894	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1123863004895	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1123863004896	RNA binding surface [nucleotide binding]; other site
1123863004897	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1123863004898	active site
1123863004899	uracil binding [chemical binding]; other site
1123863004900	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863004901	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1123863004902	putative substrate translocation pore; other site
1123863004903	YejG-like protein; Region: YejG; pfam13989
1123863004904	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1123863004905	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863004906	Walker A/P-loop; other site
1123863004907	ATP binding site [chemical binding]; other site
1123863004908	Q-loop/lid; other site
1123863004909	ABC transporter signature motif; other site
1123863004910	Walker B; other site
1123863004911	D-loop; other site
1123863004912	H-loop/switch region; other site
1123863004913	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863004914	Walker A/P-loop; other site
1123863004915	ATP binding site [chemical binding]; other site
1123863004916	Q-loop/lid; other site
1123863004917	ABC transporter signature motif; other site
1123863004918	Walker B; other site
1123863004919	D-loop; other site
1123863004920	H-loop/switch region; other site
1123863004921	microcin C ABC transporter permease; Provisional; Region: PRK15021
1123863004922	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004923	dimer interface [polypeptide binding]; other site
1123863004924	conserved gate region; other site
1123863004925	putative PBP binding loops; other site
1123863004926	ABC-ATPase subunit interface; other site
1123863004927	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1123863004928	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863004929	dimer interface [polypeptide binding]; other site
1123863004930	conserved gate region; other site
1123863004931	putative PBP binding loops; other site
1123863004932	ABC-ATPase subunit interface; other site
1123863004933	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1123863004934	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1123863004935	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863004936	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1123863004937	NlpC/P60 family; Region: NLPC_P60; pfam00877
1123863004938	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1123863004939	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1123863004940	active site
1123863004941	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1123863004942	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1123863004943	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; cl08458
1123863004944	elongation factor P; Provisional; Region: PRK04542
1123863004945	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1123863004946	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1123863004947	RNA binding site [nucleotide binding]; other site
1123863004948	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1123863004949	RNA binding site [nucleotide binding]; other site
1123863004950	Flagellin N-methylase; Region: FliB; pfam03692
1123863004951	benzoate transport; Region: 2A0115; TIGR00895
1123863004952	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863004953	putative substrate translocation pore; other site
1123863004954	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863004955	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863004956	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863004957	DNA binding site [nucleotide binding]
1123863004958	domain linker motif; other site
1123863004959	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1123863004960	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1123863004961	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1123863004962	inhibitor site; inhibition site
1123863004963	active site
1123863004964	dimer interface [polypeptide binding]; other site
1123863004965	catalytic residue [active]
1123863004966	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1123863004967	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1123863004968	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1123863004969	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863004970	active site
1123863004971	phosphorylation site [posttranslational modification]
1123863004972	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1123863004973	dimerization domain swap beta strand [polypeptide binding]; other site
1123863004974	regulatory protein interface [polypeptide binding]; other site
1123863004975	active site
1123863004976	regulatory phosphorylation site [posttranslational modification]; other site
1123863004977	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1123863004978	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1123863004979	putative substrate binding site [chemical binding]; other site
1123863004980	putative ATP binding site [chemical binding]; other site
1123863004981	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1123863004982	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1123863004983	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1123863004984	active site
1123863004985	P-loop; other site
1123863004986	phosphorylation site [posttranslational modification]
1123863004987	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1123863004988	endonuclease IV; Provisional; Region: PRK01060
1123863004989	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1123863004990	AP (apurinic/apyrimidinic) site pocket; other site
1123863004991	DNA interaction; other site
1123863004992	Metal-binding active site; metal-binding site
1123863004993	putative transposase; Provisional; Region: PRK09857
1123863004994	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1123863004995	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1123863004996	Protein of unknown function (DUF1232); Region: DUF1232; cl01318
1123863004997	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1123863004998	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863004999	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1123863005000	putative dimerization interface [polypeptide binding]; other site
1123863005001	lysine transporter; Provisional; Region: PRK10836
1123863005002	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1123863005003	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863005004	ABC-ATPase subunit  interface; other site
1123863005005	dimer interface [polypeptide binding]; other site
1123863005006	putative PBP binding regions; other site
1123863005007	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1123863005008	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1123863005009	Walker A/P-loop; other site
1123863005010	ATP binding site [chemical binding]; other site
1123863005011	Q-loop/lid; other site
1123863005012	ABC transporter signature motif; other site
1123863005013	Walker B; other site
1123863005014	D-loop; other site
1123863005015	H-loop/switch region; other site
1123863005016	S-formylglutathione hydrolase; Region: PLN02442
1123863005017	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1123863005018	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1123863005019	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1123863005020	substrate binding site [chemical binding]; other site
1123863005021	catalytic Zn binding site [ion binding]; other site
1123863005022	NAD binding site [chemical binding]; other site
1123863005023	structural Zn binding site [ion binding]; other site
1123863005024	dimer interface [polypeptide binding]; other site
1123863005025	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863005026	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863005027	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1123863005028	putative dimerization interface [polypeptide binding]; other site
1123863005029	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863005030	putative substrate translocation pore; other site
1123863005031	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1123863005032	GTP cyclohydrolase I; Provisional; Region: PLN03044
1123863005033	active site
1123863005034	Predicted membrane protein [Function unknown]; Region: COG2311
1123863005035	hypothetical protein; Provisional; Region: PRK10835
1123863005036	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1123863005037	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863005038	DNA binding site [nucleotide binding]
1123863005039	domain linker motif; other site
1123863005040	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1123863005041	dimerization interface (closed form) [polypeptide binding]; other site
1123863005042	ligand binding site [chemical binding]; other site
1123863005043	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1123863005044	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1123863005045	ligand binding site [chemical binding]; other site
1123863005046	calcium binding site [ion binding]; other site
1123863005047	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863005048	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1123863005049	Walker A/P-loop; other site
1123863005050	ATP binding site [chemical binding]; other site
1123863005051	Q-loop/lid; other site
1123863005052	ABC transporter signature motif; other site
1123863005053	Walker B; other site
1123863005054	D-loop; other site
1123863005055	H-loop/switch region; other site
1123863005056	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863005057	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863005058	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863005059	TM-ABC transporter signature motif; other site
1123863005060	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1123863005061	putative active site [active]
1123863005062	malate dehydrogenase; Provisional; Region: PRK13529
1123863005063	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1123863005064	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1123863005065	NAD(P) binding site [chemical binding]; other site
1123863005066	cytidine deaminase; Provisional; Region: PRK09027
1123863005067	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1123863005068	active site
1123863005069	catalytic motif [active]
1123863005070	Zn binding site [ion binding]; other site
1123863005071	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1123863005072	active site
1123863005073	catalytic motif [active]
1123863005074	Zn binding site [ion binding]; other site
1123863005075	hypothetical protein; Provisional; Region: PRK10711
1123863005076	hypothetical protein; Provisional; Region: PRK01821
1123863005077	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1123863005078	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1123863005079	active site
1123863005080	HIGH motif; other site
1123863005081	KMSKS motif; other site
1123863005082	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1123863005083	tRNA binding surface [nucleotide binding]; other site
1123863005084	anticodon binding site; other site
1123863005085	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1123863005086	dimer interface [polypeptide binding]; other site
1123863005087	putative tRNA-binding site [nucleotide binding]; other site
1123863005088	antiporter inner membrane protein; Provisional; Region: PRK11670
1123863005089	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1123863005090	Walker A motif; other site
1123863005091	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1123863005092	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863005093	Coenzyme A binding pocket [chemical binding]; other site
1123863005094	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1123863005095	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1123863005096	dimer interface [polypeptide binding]; other site
1123863005097	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1123863005098	catalytic triad [active]
1123863005099	peroxidatic and resolving cysteines [active]
1123863005100	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1123863005101	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1123863005102	catalytic residue [active]
1123863005103	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1123863005104	catalytic residues [active]
1123863005105	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863005106	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863005107	Predicted permeases [General function prediction only]; Region: COG0679
1123863005108	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1123863005109	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1123863005110	substrate binding site [chemical binding]; other site
1123863005111	multimerization interface [polypeptide binding]; other site
1123863005112	ATP binding site [chemical binding]; other site
1123863005113	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1123863005114	dimer interface [polypeptide binding]; other site
1123863005115	substrate binding site [chemical binding]; other site
1123863005116	ATP binding site [chemical binding]; other site
1123863005117	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863005118	phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338
1123863005119	DNA-binding site [nucleotide binding]; DNA binding site
1123863005120	FCD domain; Region: FCD; pfam07729
1123863005121	potential frameshift: common BLAST hit: gi|308187507|ref|YP_003931638.1| oxidoreductase
1123863005122	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1123863005123	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1123863005124	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1123863005125	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1123863005126	lipid kinase; Reviewed; Region: PRK13054
1123863005127	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1123863005128	putative protease; Provisional; Region: PRK15452
1123863005129	Peptidase family U32; Region: Peptidase_U32; pfam01136
1123863005130	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1123863005131	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863005132	active site
1123863005133	phosphorylation site [posttranslational modification]
1123863005134	intermolecular recognition site; other site
1123863005135	dimerization interface [polypeptide binding]; other site
1123863005136	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863005137	DNA binding site [nucleotide binding]
1123863005138	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1123863005139	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863005140	dimerization interface [polypeptide binding]; other site
1123863005141	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863005142	dimer interface [polypeptide binding]; other site
1123863005143	phosphorylation site [posttranslational modification]
1123863005144	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863005145	ATP binding site [chemical binding]; other site
1123863005146	Mg2+ binding site [ion binding]; other site
1123863005147	G-X-G motif; other site
1123863005148	putative transporter; Provisional; Region: PRK10504
1123863005149	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863005150	putative substrate translocation pore; other site
1123863005151	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1123863005152	Protein export membrane protein; Region: SecD_SecF; cl14618
1123863005153	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1123863005154	Protein export membrane protein; Region: SecD_SecF; cl14618
1123863005155	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1123863005156	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863005157	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863005158	Ubiquitin elongating factor core; Region: Ufd2P_core; pfam10408
1123863005159	putative chaperone; Provisional; Region: PRK11678
1123863005160	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1123863005161	nucleotide binding site [chemical binding]; other site
1123863005162	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1123863005163	SBD interface [polypeptide binding]; other site
1123863005164	MASE1; Region: MASE1; cl17823
1123863005165	putative diguanylate cyclase; Provisional; Region: PRK09776
1123863005166	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863005167	putative active site [active]
1123863005168	heme pocket [chemical binding]; other site
1123863005169	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863005170	putative active site [active]
1123863005171	heme pocket [chemical binding]; other site
1123863005172	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863005173	putative active site [active]
1123863005174	heme pocket [chemical binding]; other site
1123863005175	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863005176	metal binding site [ion binding]; metal-binding site
1123863005177	active site
1123863005178	I-site; other site
1123863005179	EAL domain; Region: EAL; pfam00563
1123863005180	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1123863005181	active site
1123863005182	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1123863005183	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1123863005184	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1123863005185	ATP-binding site [chemical binding]; other site
1123863005186	Sugar specificity; other site
1123863005187	Pyrimidine base specificity; other site
1123863005188	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1123863005189	trimer interface [polypeptide binding]; other site
1123863005190	active site
1123863005191	putative assembly protein; Provisional; Region: PRK10833
1123863005192	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1123863005193	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1123863005194	FOG: CBS domain [General function prediction only]; Region: COG0517
1123863005195	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1123863005196	Transporter associated domain; Region: CorC_HlyC; smart01091
1123863005197	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1123863005198	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1123863005199	polysaccharide export protein Wza; Provisional; Region: PRK15078
1123863005200	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1123863005201	SLBB domain; Region: SLBB; pfam10531
1123863005202	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1123863005203	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1123863005204	active site
1123863005205	tyrosine kinase; Provisional; Region: PRK11519
1123863005206	Chain length determinant protein; Region: Wzz; pfam02706
1123863005207	Chain length determinant protein; Region: Wzz; cl15801
1123863005208	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1123863005209	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1123863005210	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1123863005211	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1123863005212	active site
1123863005213	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1123863005214	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1123863005215	active site
1123863005216	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1123863005217	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
1123863005218	putative ADP-binding pocket [chemical binding]; other site
1123863005219	Head binding; Region: Head_binding; pfam09008
1123863005220	colanic acid biosynthesis protein; Provisional; Region: PRK10017
1123863005221	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1123863005222	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1123863005223	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1123863005224	putative ADP-binding pocket [chemical binding]; other site
1123863005225	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1123863005226	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1123863005227	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1123863005228	active site
1123863005229	tetramer interface; other site
1123863005230	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1123863005231	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1123863005232	NAD binding site [chemical binding]; other site
1123863005233	homodimer interface [polypeptide binding]; other site
1123863005234	active site
1123863005235	substrate binding site [chemical binding]; other site
1123863005236	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1123863005237	Mg++ binding site [ion binding]; other site
1123863005238	putative catalytic motif [active]
1123863005239	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1123863005240	NAD binding site [chemical binding]; other site
1123863005241	substrate binding site [chemical binding]; other site
1123863005242	homodimer interface [polypeptide binding]; other site
1123863005243	active site
1123863005244	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1123863005245	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1123863005246	NADP binding site [chemical binding]; other site
1123863005247	active site
1123863005248	putative substrate binding site [chemical binding]; other site
1123863005249	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1123863005250	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1123863005251	substrate binding site; other site
1123863005252	tetramer interface; other site
1123863005253	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1123863005254	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1123863005255	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1123863005256	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1123863005257	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1123863005258	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1123863005259	NADP-binding site; other site
1123863005260	homotetramer interface [polypeptide binding]; other site
1123863005261	substrate binding site [chemical binding]; other site
1123863005262	homodimer interface [polypeptide binding]; other site
1123863005263	active site
1123863005264	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1123863005265	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1123863005266	NADP binding site [chemical binding]; other site
1123863005267	active site
1123863005268	putative substrate binding site [chemical binding]; other site
1123863005269	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1123863005270	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1123863005271	Substrate binding site; other site
1123863005272	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1123863005273	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1123863005274	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1123863005275	metal-binding site
1123863005276	phosphomannomutase CpsG; Provisional; Region: PRK15414
1123863005277	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1123863005278	active site
1123863005279	substrate binding site [chemical binding]; other site
1123863005280	metal binding site [ion binding]; metal-binding site
1123863005281	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1123863005282	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1123863005283	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1123863005284	chain length determinant protein WzzB; Provisional; Region: PRK15471
1123863005285	Chain length determinant protein; Region: Wzz; pfam02706
1123863005286	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like subfamily; subgroup includes Pseudomonas aeruginosa AotO; Region: M14_PaAOTO_like; cd06250
1123863005287	active site
1123863005288	Zn binding site [ion binding]; other site
1123863005289	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1123863005290	lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096
1123863005291	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863005292	substrate binding pocket [chemical binding]; other site
1123863005293	membrane-bound complex binding site; other site
1123863005294	hinge residues; other site
1123863005295	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1123863005296	putative deacylase active site [active]
1123863005297	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863005298	non-specific DNA binding site [nucleotide binding]; other site
1123863005299	salt bridge; other site
1123863005300	sequence-specific DNA binding site [nucleotide binding]; other site
1123863005301	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
1123863005302	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1123863005303	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1123863005304	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1123863005305	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1123863005306	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1123863005307	metal binding site [ion binding]; metal-binding site
1123863005308	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1123863005309	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1123863005310	substrate binding site [chemical binding]; other site
1123863005311	glutamase interaction surface [polypeptide binding]; other site
1123863005312	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1123863005313	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1123863005314	catalytic residues [active]
1123863005315	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1123863005316	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1123863005317	putative active site [active]
1123863005318	oxyanion strand; other site
1123863005319	catalytic triad [active]
1123863005320	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1123863005321	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863005322	active site
1123863005323	motif I; other site
1123863005324	motif II; other site
1123863005325	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1123863005326	putative active site pocket [active]
1123863005327	4-fold oligomerization interface [polypeptide binding]; other site
1123863005328	metal binding residues [ion binding]; metal-binding site
1123863005329	3-fold/trimer interface [polypeptide binding]; other site
1123863005330	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1123863005331	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863005332	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863005333	homodimer interface [polypeptide binding]; other site
1123863005334	catalytic residue [active]
1123863005335	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1123863005336	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1123863005337	NAD binding site [chemical binding]; other site
1123863005338	dimerization interface [polypeptide binding]; other site
1123863005339	product binding site; other site
1123863005340	substrate binding site [chemical binding]; other site
1123863005341	zinc binding site [ion binding]; other site
1123863005342	catalytic residues [active]
1123863005343	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1123863005344	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1123863005345	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1123863005346	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1123863005347	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1123863005348	putative NAD(P) binding site [chemical binding]; other site
1123863005349	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1123863005350	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1123863005351	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1123863005352	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863005353	non-specific DNA binding site [nucleotide binding]; other site
1123863005354	salt bridge; other site
1123863005355	sequence-specific DNA binding site [nucleotide binding]; other site
1123863005356	Cupin domain; Region: Cupin_2; pfam07883
1123863005357	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
1123863005358	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1123863005359	catalytic triad [active]
1123863005360	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1123863005361	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1123863005362	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1123863005363	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1123863005364	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1123863005365	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863005366	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1123863005367	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1123863005368	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1123863005369	putative aldolase; Validated; Region: PRK08130
1123863005370	intersubunit interface [polypeptide binding]; other site
1123863005371	active site
1123863005372	Zn2+ binding site [ion binding]; other site
1123863005373	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
1123863005374	putative transporter; Provisional; Region: PRK09821
1123863005375	GntP family permease; Region: GntP_permease; pfam02447
1123863005376	exonuclease I; Provisional; Region: sbcB; PRK11779
1123863005377	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1123863005378	active site
1123863005379	catalytic site [active]
1123863005380	substrate binding site [chemical binding]; other site
1123863005381	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1123863005382	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1123863005383	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1123863005384	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1123863005385	Predicted membrane protein [Function unknown]; Region: COG1289
1123863005386	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1123863005387	hypothetical protein; Provisional; Region: PRK05423
1123863005388	lac repressor; Reviewed; Region: lacI; PRK09526
1123863005389	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863005390	DNA binding site [nucleotide binding]
1123863005391	domain linker motif; other site
1123863005392	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1123863005393	ligand binding site [chemical binding]; other site
1123863005394	dimerization interface (open form) [polypeptide binding]; other site
1123863005395	dimerization interface (closed form) [polypeptide binding]; other site
1123863005396	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1123863005397	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1123863005398	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1123863005399	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1123863005400	Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296
1123863005401	Protein of unknown function (DUF796); Region: DUF796; pfam05638
1123863005402	Protein of unknown function (DUF796); Region: DUF796; pfam05638
1123863005403	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863005404	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
1123863005405	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
1123863005406	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1123863005407	NAD binding site [chemical binding]; other site
1123863005408	catalytic residues [active]
1123863005409	substrate binding site [chemical binding]; other site
1123863005410	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
1123863005411	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1123863005412	transcriptional activator RhaR; Provisional; Region: PRK13501
1123863005413	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1123863005414	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863005415	transcriptional activator RhaS; Provisional; Region: PRK13503
1123863005416	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1123863005417	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863005418	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1123863005419	N- and C-terminal domain interface [polypeptide binding]; other site
1123863005420	active site
1123863005421	putative catalytic site [active]
1123863005422	metal binding site [ion binding]; metal-binding site
1123863005423	ATP binding site [chemical binding]; other site
1123863005424	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1123863005425	carbohydrate binding site [chemical binding]; other site
1123863005426	L-rhamnose isomerase; Provisional; Region: PRK01076
1123863005427	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1123863005428	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
1123863005429	intersubunit interface [polypeptide binding]; other site
1123863005430	active site
1123863005431	Zn2+ binding site [ion binding]; other site
1123863005432	Domain of unknown function (DUF718); Region: DUF718; cl01281
1123863005433	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1123863005434	potential frameshift: common BLAST hit: gi|308187400|ref|YP_003931531.1| transcriptional regulator
1123863005435	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1123863005436	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1123863005437	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863005438	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1123863005439	Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen; Region: GT8_Glycogenin; cd02537
1123863005440	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
1123863005441	substrate binding site; other site
1123863005442	Manganese binding site; other site
1123863005443	dimer interface; other site
1123863005444	FAD-linked oxidoreductase; Region: bact_FAD_ox; TIGR01679
1123863005445	FAD binding domain; Region: FAD_binding_4; pfam01565
1123863005446	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
1123863005447	pyrimidine utilization regulatory protein R; Region: RutR; TIGR03613
1123863005448	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863005449	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1123863005450	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1123863005451	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863005452	putative DNA binding site [nucleotide binding]; other site
1123863005453	putative Zn2+ binding site [ion binding]; other site
1123863005454	AsnC family; Region: AsnC_trans_reg; pfam01037
1123863005455	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1123863005456	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
1123863005457	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1123863005458	active site
1123863005459	substrate binding site [chemical binding]; other site
1123863005460	Mg2+ binding site [ion binding]; other site
1123863005461	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1123863005462	catalytic loop [active]
1123863005463	iron binding site [ion binding]; other site
1123863005464	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863005465	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863005466	dimer interface [polypeptide binding]; other site
1123863005467	putative CheW interface [polypeptide binding]; other site
1123863005468	Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301
1123863005469	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1123863005470	putative ligand binding site [chemical binding]; other site
1123863005471	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863005472	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863005473	Walker A/P-loop; other site
1123863005474	ATP binding site [chemical binding]; other site
1123863005475	Q-loop/lid; other site
1123863005476	ABC transporter signature motif; other site
1123863005477	Walker B; other site
1123863005478	D-loop; other site
1123863005479	H-loop/switch region; other site
1123863005480	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863005481	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863005482	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863005483	TM-ABC transporter signature motif; other site
1123863005484	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1123863005485	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863005486	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1123863005487	putative dimerization interface [polypeptide binding]; other site
1123863005488	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
1123863005489	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863005490	The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413
1123863005491	substrate binding site [chemical binding]; other site
1123863005492	dimerization interface [polypeptide binding]; other site
1123863005493	succinic semialdehyde dehydrogenase; Region: PLN02278
1123863005494	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1123863005495	tetramerization interface [polypeptide binding]; other site
1123863005496	NAD(P) binding site [chemical binding]; other site
1123863005497	catalytic residues [active]
1123863005498	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1123863005499	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1123863005500	NAD(P) binding site [chemical binding]; other site
1123863005501	catalytic residues [active]
1123863005502	2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428
1123863005503	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863005504	motif II; other site
1123863005505	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1123863005506	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1123863005507	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1123863005508	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_17; cd08503
1123863005509	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1123863005510	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863005511	dimer interface [polypeptide binding]; other site
1123863005512	conserved gate region; other site
1123863005513	putative PBP binding loops; other site
1123863005514	ABC-ATPase subunit interface; other site
1123863005515	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1123863005516	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863005517	dimer interface [polypeptide binding]; other site
1123863005518	conserved gate region; other site
1123863005519	ABC-ATPase subunit interface; other site
1123863005520	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1123863005521	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863005522	Walker A/P-loop; other site
1123863005523	ATP binding site [chemical binding]; other site
1123863005524	Q-loop/lid; other site
1123863005525	ABC transporter signature motif; other site
1123863005526	Walker B; other site
1123863005527	D-loop; other site
1123863005528	H-loop/switch region; other site
1123863005529	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863005530	Walker A/P-loop; other site
1123863005531	ATP binding site [chemical binding]; other site
1123863005532	Q-loop/lid; other site
1123863005533	ABC transporter signature motif; other site
1123863005534	Walker B; other site
1123863005535	D-loop; other site
1123863005536	H-loop/switch region; other site
1123863005537	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1123863005538	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1123863005539	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1123863005540	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863005541	Coenzyme A binding pocket [chemical binding]; other site
1123863005542	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1123863005543	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1123863005544	putative ligand binding site [chemical binding]; other site
1123863005545	NAD binding site [chemical binding]; other site
1123863005546	dimerization interface [polypeptide binding]; other site
1123863005547	catalytic site [active]
1123863005548	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1123863005549	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1123863005550	metal binding site [ion binding]; metal-binding site
1123863005551	putative dimer interface [polypeptide binding]; other site
1123863005552	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
1123863005553	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863005554	inhibitor-cofactor binding pocket; inhibition site
1123863005555	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863005556	catalytic residue [active]
1123863005557	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1123863005558	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863005559	putative DNA binding site [nucleotide binding]; other site
1123863005560	putative Zn2+ binding site [ion binding]; other site
1123863005561	AsnC family; Region: AsnC_trans_reg; pfam01037
1123863005562	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1123863005563	active site
1123863005564	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1123863005565	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1123863005566	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1123863005567	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1123863005568	Na binding site [ion binding]; other site
1123863005569	Isochorismatase family; Region: Isochorismatase; pfam00857
1123863005570	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1123863005571	catalytic triad [active]
1123863005572	conserved cis-peptide bond; other site
1123863005573	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
1123863005574	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863005575	DNA-binding site [nucleotide binding]; DNA binding site
1123863005576	UTRA domain; Region: UTRA; pfam07702
1123863005577	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
1123863005578	carbon-phosphorus lyase complex subunit; Validated; Region: phnH; PRK10147
1123863005579	Bacterial phosphonate metabolism protein (PhnI); Region: PhnI; pfam05861
1123863005580	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
1123863005581	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
1123863005582	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863005583	Walker A/P-loop; other site
1123863005584	ATP binding site [chemical binding]; other site
1123863005585	Q-loop/lid; other site
1123863005586	ABC transporter signature motif; other site
1123863005587	Walker B; other site
1123863005588	D-loop; other site
1123863005589	H-loop/switch region; other site
1123863005590	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1123863005591	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
1123863005592	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863005593	Walker A/P-loop; other site
1123863005594	ATP binding site [chemical binding]; other site
1123863005595	Q-loop/lid; other site
1123863005596	ABC transporter signature motif; other site
1123863005597	Walker B; other site
1123863005598	D-loop; other site
1123863005599	H-loop/switch region; other site
1123863005600	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
1123863005601	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
1123863005602	active site
1123863005603	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1123863005604	putative hydrolase; Provisional; Region: PRK02113
1123863005605	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1123863005606	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
1123863005607	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1123863005608	Walker A/P-loop; other site
1123863005609	ATP binding site [chemical binding]; other site
1123863005610	Q-loop/lid; other site
1123863005611	ABC transporter signature motif; other site
1123863005612	Walker B; other site
1123863005613	D-loop; other site
1123863005614	H-loop/switch region; other site
1123863005615	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
1123863005616	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1123863005617	substrate binding pocket [chemical binding]; other site
1123863005618	membrane-bound complex binding site; other site
1123863005619	hinge residues; other site
1123863005620	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1123863005621	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863005622	dimer interface [polypeptide binding]; other site
1123863005623	conserved gate region; other site
1123863005624	putative PBP binding loops; other site
1123863005625	ABC-ATPase subunit interface; other site
1123863005626	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1123863005627	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863005628	dimer interface [polypeptide binding]; other site
1123863005629	conserved gate region; other site
1123863005630	ABC-ATPase subunit interface; other site
1123863005631	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1123863005632	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863005633	dimerization interface [polypeptide binding]; other site
1123863005634	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1123863005635	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863005636	ATP binding site [chemical binding]; other site
1123863005637	Mg2+ binding site [ion binding]; other site
1123863005638	G-X-G motif; other site
1123863005639	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1123863005640	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863005641	active site
1123863005642	phosphorylation site [posttranslational modification]
1123863005643	intermolecular recognition site; other site
1123863005644	dimerization interface [polypeptide binding]; other site
1123863005645	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863005646	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863005647	Walker A/P-loop; other site
1123863005648	ATP binding site [chemical binding]; other site
1123863005649	Q-loop/lid; other site
1123863005650	ABC transporter signature motif; other site
1123863005651	Walker B; other site
1123863005652	D-loop; other site
1123863005653	H-loop/switch region; other site
1123863005654	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863005655	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863005656	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863005657	TM-ABC transporter signature motif; other site
1123863005658	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1123863005659	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
1123863005660	putative ligand binding site [chemical binding]; other site
1123863005661	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
1123863005662	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1123863005663	intersubunit interface [polypeptide binding]; other site
1123863005664	active site
1123863005665	zinc binding site [ion binding]; other site
1123863005666	Na+ binding site [ion binding]; other site
1123863005667	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1123863005668	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863005669	substrate binding site [chemical binding]; other site
1123863005670	ATP binding site [chemical binding]; other site
1123863005671	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1123863005672	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863005673	active site
1123863005674	phosphorylation site [posttranslational modification]
1123863005675	intermolecular recognition site; other site
1123863005676	dimerization interface [polypeptide binding]; other site
1123863005677	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863005678	DNA binding site [nucleotide binding]
1123863005679	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1123863005680	AMP nucleosidase; Provisional; Region: PRK08292
1123863005681	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1123863005682	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1123863005683	MATE family multidrug exporter; Provisional; Region: PRK10189
1123863005684	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1123863005685	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1123863005686	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1123863005687	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1123863005688	hypothetical protein; Provisional; Region: PRK07033
1123863005689	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1123863005690	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1123863005691	ligand binding site [chemical binding]; other site
1123863005692	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
1123863005693	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1123863005694	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1123863005695	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; pfam09867
1123863005696	type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363
1123863005697	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1123863005698	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
1123863005699	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1123863005700	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1123863005701	Protein of unknown function (DUF796); Region: DUF796; pfam05638
1123863005702	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1123863005703	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1123863005704	Protein of unknown function (DUF3380); Region: DUF3380; pfam11860
1123863005705	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1123863005706	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1123863005707	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1123863005708	phosphopeptide binding site; other site
1123863005709	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1123863005710	active site
1123863005711	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
1123863005712	ImpE protein; Region: ImpE; pfam07024
1123863005713	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1123863005714	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1123863005715	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1123863005716	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1123863005717	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1123863005718	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863005719	Walker A motif; other site
1123863005720	ATP binding site [chemical binding]; other site
1123863005721	Walker B motif; other site
1123863005722	arginine finger; other site
1123863005723	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863005724	Walker A motif; other site
1123863005725	ATP binding site [chemical binding]; other site
1123863005726	Walker B motif; other site
1123863005727	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1123863005728	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1123863005729	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1123863005730	active site
1123863005731	ATP binding site [chemical binding]; other site
1123863005732	substrate binding site [chemical binding]; other site
1123863005733	activation loop (A-loop); other site
1123863005734	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1123863005735	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1123863005736	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1123863005737	Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; pfam09937
1123863005738	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1123863005739	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1123863005740	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1123863005741	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1123863005742	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1123863005743	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1123863005744	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1123863005745	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1123863005746	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1123863005747	Protein of unknown function (DUF3540); Region: DUF3540; pfam12059
1123863005748	Domain of unknown function (DUF4150); Region: DUF4150; pfam13665
1123863005749	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1123863005750	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1123863005751	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1123863005752	Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193
1123863005753	Lysozyme subfamily 2; Region: LYZ2; smart00047
1123863005754	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1123863005755	Domain of unknown function (DUF1795); Region: DUF1795; cl02256
1123863005756	PAAR motif; Region: PAAR_motif; pfam05488
1123863005757	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1123863005758	RHS Repeat; Region: RHS_repeat; pfam05593
1123863005759	RHS Repeat; Region: RHS_repeat; pfam05593
1123863005760	RHS Repeat; Region: RHS_repeat; pfam05593
1123863005761	RHS protein; Region: RHS; pfam03527
1123863005762	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1123863005763	Protein of unknown function (DUF4237); Region: DUF4237; pfam14021
1123863005764	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1123863005765	RHS protein; Region: RHS; pfam03527
1123863005766	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1123863005767	RHS protein; Region: RHS; pfam03527
1123863005768	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863005769	active site
1123863005770	phosphorylation site [posttranslational modification]
1123863005771	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1123863005772	active site
1123863005773	P-loop; other site
1123863005774	phosphorylation site [posttranslational modification]
1123863005775	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1123863005776	alpha-mannosidase; Provisional; Region: PRK09819
1123863005777	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
1123863005778	active site
1123863005779	metal binding site [ion binding]; metal-binding site
1123863005780	catalytic site [active]
1123863005781	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
1123863005782	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1123863005783	HTH domain; Region: HTH_11; cl17392
1123863005784	PRD domain; Region: PRD; pfam00874
1123863005785	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1123863005786	active site
1123863005787	P-loop; other site
1123863005788	phosphorylation site [posttranslational modification]
1123863005789	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863005790	active site
1123863005791	phosphorylation site [posttranslational modification]
1123863005792	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1123863005793	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1123863005794	putative dimer interface [polypeptide binding]; other site
1123863005795	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1123863005796	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863005797	Walker A/P-loop; other site
1123863005798	ATP binding site [chemical binding]; other site
1123863005799	Q-loop/lid; other site
1123863005800	ABC transporter signature motif; other site
1123863005801	Walker B; other site
1123863005802	D-loop; other site
1123863005803	H-loop/switch region; other site
1123863005804	Metal binding protein TroA_a.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148
1123863005805	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
1123863005806	putative ligand binding residues [chemical binding]; other site
1123863005807	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1123863005808	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863005809	ABC-ATPase subunit  interface; other site
1123863005810	dimer interface [polypeptide binding]; other site
1123863005811	putative PBP binding regions; other site
1123863005812	enterobactin exporter EntS; Provisional; Region: PRK10489
1123863005813	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863005814	putative substrate translocation pore; other site
1123863005815	ferrochelatase; Reviewed; Region: hemH; PRK00035
1123863005816	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1123863005817	C-terminal domain interface [polypeptide binding]; other site
1123863005818	active site
1123863005819	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1123863005820	active site
1123863005821	N-terminal domain interface [polypeptide binding]; other site
1123863005822	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1123863005823	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1123863005824	PemK-like protein; Region: PemK; cl00995
1123863005825	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1123863005826	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
1123863005827	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1123863005828	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1123863005829	Zn2+ binding site [ion binding]; other site
1123863005830	Mg2+ binding site [ion binding]; other site
1123863005831	bifunctional SbtC-like/phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Provisional; Region: PRK13982
1123863005832	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1123863005833	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1123863005834	dimer interface [polypeptide binding]; other site
1123863005835	ligand binding site [chemical binding]; other site
1123863005836	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863005837	dimer interface [polypeptide binding]; other site
1123863005838	putative CheW interface [polypeptide binding]; other site
1123863005839	DNA cytosine methylase; Provisional; Region: PRK10458
1123863005840	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1123863005841	cofactor binding site; other site
1123863005842	DNA binding site [nucleotide binding]
1123863005843	substrate interaction site [chemical binding]; other site
1123863005844	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1123863005845	additional DNA contacts [nucleotide binding]; other site
1123863005846	mismatch recognition site; other site
1123863005847	active site
1123863005848	zinc binding site [ion binding]; other site
1123863005849	DNA intercalation site [nucleotide binding]; other site
1123863005850	hypothetical protein; Provisional; Region: PRK10062
1123863005851	putative glucosyl-3-phosphoglycerate synthase; Provisional; Region: PRK13915
1123863005852	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1123863005853	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863005854	active site
1123863005855	motif I; other site
1123863005856	motif II; other site
1123863005857	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
1123863005858	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1123863005859	hypothetical protein; Provisional; Region: PRK10708
1123863005860	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1123863005861	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1123863005862	dimer interface [polypeptide binding]; other site
1123863005863	ligand binding site [chemical binding]; other site
1123863005864	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863005865	dimerization interface [polypeptide binding]; other site
1123863005866	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863005867	dimer interface [polypeptide binding]; other site
1123863005868	putative CheW interface [polypeptide binding]; other site
1123863005869	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1123863005870	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1123863005871	DNA binding residues [nucleotide binding]
1123863005872	dimerization interface [polypeptide binding]; other site
1123863005873	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1123863005874	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1123863005875	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1123863005876	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1123863005877	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1123863005878	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1123863005879	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1123863005880	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1123863005881	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1123863005882	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
1123863005883	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1123863005884	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1123863005885	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1123863005886	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1123863005887	Walker A motif/ATP binding site; other site
1123863005888	Walker B motif; other site
1123863005889	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1123863005890	Flagellar assembly protein FliH; Region: FliH; pfam02108
1123863005891	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1123863005892	FliG C-terminal domain; Region: FliG_C; pfam01706
1123863005893	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1123863005894	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1123863005895	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1123863005896	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1123863005897	Integrase core domain; Region: rve_3; pfam13683
1123863005898	potential frameshift: common BLAST hit: gi|271501363|ref|YP_003334388.1| transposase IS3/IS911 family protein
1123863005899	Integrase core domain; Region: rve_3; cl15866
1123863005900	Integrase core domain; Region: rve_3; pfam13683
1123863005901	Integrase core domain; Region: rve; pfam00665
1123863005902	Transposase; Region: HTH_Tnp_1; cl17663
1123863005903	Sulfatase; Region: Sulfatase; cl17466
1123863005904	DinI-like family; Region: DinI; cl11630
1123863005905	anti-RssB factor; Provisional; Region: PRK10244
1123863005906	lipoprotein; Provisional; Region: PRK10397
1123863005907	Methyltransferase domain; Region: Methyltransf_24; pfam13578
1123863005908	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1123863005909	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1123863005910	active site
1123863005911	Na/Ca binding site [ion binding]; other site
1123863005912	catalytic site [active]
1123863005913	Flagellar protein FliT; Region: FliT; cl05125
1123863005914	flagellar protein FliS; Validated; Region: fliS; PRK05685
1123863005915	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1123863005916	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1123863005917	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1123863005918	flagellin; Validated; Region: PRK06819
1123863005919	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1123863005920	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1123863005921	flagellin; Reviewed; Region: PRK08869
1123863005922	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1123863005923	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1123863005924	flagellin; Reviewed; Region: PRK08869
1123863005925	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1123863005926	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1123863005927	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1123863005928	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1123863005929	inhibitor-cofactor binding pocket; inhibition site
1123863005930	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863005931	catalytic residue [active]
1123863005932	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1123863005933	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1123863005934	active site
1123863005935	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1123863005936	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1123863005937	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1123863005938	Probable Catalytic site; other site
1123863005939	metal-binding site
1123863005940	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
1123863005941	Formyltransferase, catalytic core domain; Region: FMT_core; cd08369
1123863005942	active site
1123863005943	cosubstrate binding site; other site
1123863005944	substrate binding site [chemical binding]; other site
1123863005945	catalytic site [active]
1123863005946	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1123863005947	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
1123863005948	NADP binding site [chemical binding]; other site
1123863005949	active site
1123863005950	putative substrate binding site [chemical binding]; other site
1123863005951	HNH endonuclease; Region: HNH_2; pfam13391
1123863005952	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1123863005953	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863005954	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1123863005955	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1123863005956	DNA binding residues [nucleotide binding]
1123863005957	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1123863005958	D-cysteine desulfhydrase; Validated; Region: PRK03910
1123863005959	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1123863005960	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863005961	catalytic residue [active]
1123863005962	cystine transporter subunit; Provisional; Region: PRK11260
1123863005963	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863005964	substrate binding pocket [chemical binding]; other site
1123863005965	membrane-bound complex binding site; other site
1123863005966	hinge residues; other site
1123863005967	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863005968	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863005969	dimer interface [polypeptide binding]; other site
1123863005970	conserved gate region; other site
1123863005971	putative PBP binding loops; other site
1123863005972	ABC-ATPase subunit interface; other site
1123863005973	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1123863005974	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863005975	Walker A/P-loop; other site
1123863005976	ATP binding site [chemical binding]; other site
1123863005977	Q-loop/lid; other site
1123863005978	ABC transporter signature motif; other site
1123863005979	Walker B; other site
1123863005980	D-loop; other site
1123863005981	H-loop/switch region; other site
1123863005982	Predicted membrane protein [Function unknown]; Region: COG4763
1123863005983	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1123863005984	Predicted membrane protein [Function unknown]; Region: COG4763
1123863005985	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1123863005986	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1123863005987	Predicted transcriptional regulator [Transcription]; Region: COG3905
1123863005988	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1123863005989	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1123863005990	Glutamate binding site [chemical binding]; other site
1123863005991	NAD binding site [chemical binding]; other site
1123863005992	catalytic residues [active]
1123863005993	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1123863005994	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1123863005995	Na binding site [ion binding]; other site
1123863005996	Iron permease FTR1 family; Region: FTR1; cl00475
1123863005997	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
1123863005998	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1123863005999	Imelysin; Region: Peptidase_M75; pfam09375
1123863006000	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1123863006001	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1123863006002	hypothetical protein; Provisional; Region: PRK10536
1123863006003	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1123863006004	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1123863006005	sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022
1123863006006	active site
1123863006007	benzoate transport; Region: 2A0115; TIGR00895
1123863006008	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863006009	putative substrate translocation pore; other site
1123863006010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863006011	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1123863006012	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1123863006013	non-prolyl cis peptide bond; other site
1123863006014	active site
1123863006015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529
1123863006016	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1123863006017	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1123863006018	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1123863006019	active site
1123863006020	dimer interface [polypeptide binding]; other site
1123863006021	non-prolyl cis peptide bond; other site
1123863006022	insertion regions; other site
1123863006023	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1123863006024	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863006025	Walker A motif; other site
1123863006026	ATP binding site [chemical binding]; other site
1123863006027	Walker B motif; other site
1123863006028	arginine finger; other site
1123863006029	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1123863006030	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1123863006031	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863006032	substrate binding pocket [chemical binding]; other site
1123863006033	membrane-bound complex binding site; other site
1123863006034	hinge residues; other site
1123863006035	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1123863006036	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863006037	substrate binding pocket [chemical binding]; other site
1123863006038	membrane-bound complex binding site; other site
1123863006039	hinge residues; other site
1123863006040	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1123863006041	Predicted transcriptional regulator [Transcription]; Region: COG2944
1123863006042	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863006043	non-specific DNA binding site [nucleotide binding]; other site
1123863006044	salt bridge; other site
1123863006045	sequence-specific DNA binding site [nucleotide binding]; other site
1123863006046	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
1123863006047	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1123863006048	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1123863006049	active site
1123863006050	DNA binding site [nucleotide binding]
1123863006051	Int/Topo IB signature motif; other site
1123863006052	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1123863006053	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1123863006054	cofactor binding site; other site
1123863006055	DNA binding site [nucleotide binding]
1123863006056	substrate interaction site [chemical binding]; other site
1123863006057	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1123863006058	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
1123863006059	AAA domain; Region: AAA_22; pfam13401
1123863006060	exodeoxyribonuclease X; Provisional; Region: PRK07983
1123863006061	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1123863006062	active site
1123863006063	catalytic site [active]
1123863006064	substrate binding site [chemical binding]; other site
1123863006065	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1123863006066	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1123863006067	replicative DNA helicase; Region: DnaB; TIGR00665
1123863006068	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1123863006069	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1123863006070	Walker A motif; other site
1123863006071	ATP binding site [chemical binding]; other site
1123863006072	Walker B motif; other site
1123863006073	DNA binding loops [nucleotide binding]
1123863006074	Endodeoxyribonuclease RusA; Region: RusA; cl01885
1123863006075	potential protein location (hypothetical protein) that overlaps protein (endodeoxyribonuclease RusA)
1123863006076	Antitermination protein; Region: Antiterm; pfam03589
1123863006077	Antitermination protein; Region: Antiterm; pfam03589
1123863006078	Lysis protein S; Region: Lysis_S; pfam04971
1123863006079	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1123863006080	catalytic residues [active]
1123863006081	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1123863006082	Uncharacterized conserved protein (DUF2280); Region: DUF2280; pfam10045
1123863006083	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1123863006084	Phage terminase large subunit; Region: Terminase_3; cl12054
1123863006085	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
1123863006086	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
1123863006087	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1123863006088	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
1123863006089	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834
1123863006090	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
1123863006091	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
1123863006092	Superfamily II helicase, archaea-specific [General function prediction only]; Region: COG1202
1123863006093	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
1123863006094	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
1123863006095	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1123863006096	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1123863006097	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1123863006098	catalytic residue [active]
1123863006099	potential frameshift: common BLAST hit: gi|224582861|ref|YP_002636659.1| bacteriophage protein
1123863006100	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cl00327
1123863006101	putative translocon binding site; other site
1123863006102	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1123863006103	Baseplate J-like protein; Region: Baseplate_J; cl01294
1123863006104	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
1123863006105	long tail fiber, proximal subunit; Provisional; Region: 34; PHA02584
1123863006106	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1123863006107	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1123863006108	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1123863006109	HAMP domain; Region: HAMP; pfam00672
1123863006110	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863006111	dimer interface [polypeptide binding]; other site
1123863006112	phosphorylation site [posttranslational modification]
1123863006113	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863006114	ATP binding site [chemical binding]; other site
1123863006115	Mg2+ binding site [ion binding]; other site
1123863006116	G-X-G motif; other site
1123863006117	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1123863006118	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863006119	active site
1123863006120	phosphorylation site [posttranslational modification]
1123863006121	intermolecular recognition site; other site
1123863006122	dimerization interface [polypeptide binding]; other site
1123863006123	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863006124	DNA binding site [nucleotide binding]
1123863006125	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
1123863006126	Trehalose-phosphatase; Region: Trehalose_PPase; pfam02358
1123863006127	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1123863006128	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1123863006129	active site
1123863006130	homotetramer interface [polypeptide binding]; other site
1123863006131	transcriptional activator FlhD; Provisional; Region: PRK02909
1123863006132	transcriptional activator FlhC; Provisional; Region: PRK12722
1123863006133	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1123863006134	flagellar motor protein MotA; Validated; Region: PRK09110
1123863006135	flagellar motor protein MotB; Validated; Region: motB; PRK09041
1123863006136	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1123863006137	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1123863006138	ligand binding site [chemical binding]; other site
1123863006139	chemotaxis protein CheA; Provisional; Region: PRK10547
1123863006140	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1123863006141	putative binding surface; other site
1123863006142	active site
1123863006143	CheY binding; Region: CheY-binding; pfam09078
1123863006144	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1123863006145	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863006146	ATP binding site [chemical binding]; other site
1123863006147	Mg2+ binding site [ion binding]; other site
1123863006148	G-X-G motif; other site
1123863006149	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1123863006150	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1123863006151	putative CheA interaction surface; other site
1123863006152	methyl-accepting protein IV; Provisional; Region: PRK09793
1123863006153	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1123863006154	dimer interface [polypeptide binding]; other site
1123863006155	ligand binding site [chemical binding]; other site
1123863006156	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863006157	dimerization interface [polypeptide binding]; other site
1123863006158	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863006159	dimer interface [polypeptide binding]; other site
1123863006160	putative CheW interface [polypeptide binding]; other site
1123863006161	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1123863006162	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1123863006163	dimer interface [polypeptide binding]; other site
1123863006164	ligand binding site [chemical binding]; other site
1123863006165	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863006166	dimerization interface [polypeptide binding]; other site
1123863006167	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863006168	dimer interface [polypeptide binding]; other site
1123863006169	putative CheW interface [polypeptide binding]; other site
1123863006170	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1123863006171	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1123863006172	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863006173	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1123863006174	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863006175	active site
1123863006176	phosphorylation site [posttranslational modification]
1123863006177	intermolecular recognition site; other site
1123863006178	dimerization interface [polypeptide binding]; other site
1123863006179	CheB methylesterase; Region: CheB_methylest; pfam01339
1123863006180	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1123863006181	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863006182	active site
1123863006183	phosphorylation site [posttranslational modification]
1123863006184	intermolecular recognition site; other site
1123863006185	dimerization interface [polypeptide binding]; other site
1123863006186	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1123863006187	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK12468
1123863006188	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1123863006189	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1123863006190	FHIPEP family; Region: FHIPEP; pfam00771
1123863006191	Flagellar protein FlhE; Region: FlhE; pfam06366
1123863006192	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1123863006193	amphipathic channel; other site
1123863006194	Asn-Pro-Ala signature motifs; other site
1123863006195	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1123863006196	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1123863006197	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1123863006198	active site
1123863006199	HIGH motif; other site
1123863006200	KMSK motif region; other site
1123863006201	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1123863006202	tRNA binding surface [nucleotide binding]; other site
1123863006203	anticodon binding site; other site
1123863006204	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863006205	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1123863006206	putative metal binding site [ion binding]; other site
1123863006207	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
1123863006208	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863006209	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863006210	homodimer interface [polypeptide binding]; other site
1123863006211	catalytic residue [active]
1123863006212	copper homeostasis protein CutC; Provisional; Region: PRK11572
1123863006213	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1123863006214	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1123863006215	dimer interface [polypeptide binding]; other site
1123863006216	active site
1123863006217	metal binding site [ion binding]; metal-binding site
1123863006218	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1123863006219	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1123863006220	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863006221	S-adenosylmethionine binding site [chemical binding]; other site
1123863006222	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863006223	S-adenosylmethionine binding site [chemical binding]; other site
1123863006224	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1123863006225	hypothetical protein; Provisional; Region: PRK10302
1123863006226	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1123863006227	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1123863006228	dimer interface [polypeptide binding]; other site
1123863006229	anticodon binding site; other site
1123863006230	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1123863006231	homodimer interface [polypeptide binding]; other site
1123863006232	motif 1; other site
1123863006233	active site
1123863006234	motif 2; other site
1123863006235	GAD domain; Region: GAD; pfam02938
1123863006236	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1123863006237	active site
1123863006238	motif 3; other site
1123863006239	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1123863006240	nudix motif; other site
1123863006241	hypothetical protein; Validated; Region: PRK00110
1123863006242	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1123863006243	active site
1123863006244	putative DNA-binding cleft [nucleotide binding]; other site
1123863006245	dimer interface [polypeptide binding]; other site
1123863006246	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1123863006247	RuvA N terminal domain; Region: RuvA_N; pfam01330
1123863006248	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1123863006249	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1123863006250	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863006251	Walker A motif; other site
1123863006252	ATP binding site [chemical binding]; other site
1123863006253	Walker B motif; other site
1123863006254	arginine finger; other site
1123863006255	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1123863006256	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1123863006257	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863006258	ABC-ATPase subunit  interface; other site
1123863006259	dimer interface [polypeptide binding]; other site
1123863006260	putative PBP binding regions; other site
1123863006261	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1123863006262	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1123863006263	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1123863006264	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1123863006265	metal binding site [ion binding]; metal-binding site
1123863006266	putative peptidase; Provisional; Region: PRK11649
1123863006267	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1123863006268	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1123863006269	Peptidase family M23; Region: Peptidase_M23; pfam01551
1123863006270	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1123863006271	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1123863006272	putative acyl-acceptor binding pocket; other site
1123863006273	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1123863006274	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863006275	putative substrate translocation pore; other site
1123863006276	pyruvate kinase; Provisional; Region: PRK05826
1123863006277	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1123863006278	domain interfaces; other site
1123863006279	active site
1123863006280	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1123863006281	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863006282	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1123863006283	putative active site [active]
1123863006284	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1123863006285	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1123863006286	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1123863006287	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1123863006288	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1123863006289	active site
1123863006290	intersubunit interface [polypeptide binding]; other site
1123863006291	catalytic residue [active]
1123863006292	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1123863006293	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863006294	ATP-grasp domain; Region: ATP-grasp; pfam02222
1123863006295	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1123863006296	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1123863006297	putative metal binding site [ion binding]; other site
1123863006298	protease 2; Provisional; Region: PRK10115
1123863006299	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1123863006300	exodeoxyribonuclease X; Provisional; Region: PRK07983
1123863006301	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1123863006302	active site
1123863006303	catalytic site [active]
1123863006304	substrate binding site [chemical binding]; other site
1123863006305	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1123863006306	CopC domain; Region: CopC; pfam04234
1123863006307	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1123863006308	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1123863006309	Phage tail tube protein FII; Region: Phage_tube; cl01390
1123863006310	terminase ATPase subunit; Provisional; Region: P; PHA02535
1123863006311	portal vertex protein; Provisional; Region: Q; PHA02536
1123863006312	Phage portal protein; Region: Phage_portal; pfam04860
1123863006313	potential frameshift: common BLAST hit: gi|347758915|ref|YP_004866477.1| SEC-C motif family protein
1123863006314	SEC-C motif; Region: SEC-C; pfam02810
1123863006315	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863006316	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863006317	dimer interface [polypeptide binding]; other site
1123863006318	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1123863006319	putative CheW interface [polypeptide binding]; other site
1123863006320	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1123863006321	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863006322	DNA-binding site [nucleotide binding]; DNA binding site
1123863006323	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1123863006324	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1123863006325	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1123863006326	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1123863006327	active site turn [active]
1123863006328	phosphorylation site [posttranslational modification]
1123863006329	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1123863006330	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1123863006331	NAD binding site [chemical binding]; other site
1123863006332	sugar binding site [chemical binding]; other site
1123863006333	divalent metal binding site [ion binding]; other site
1123863006334	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1123863006335	dimer interface [polypeptide binding]; other site
1123863006336	MEKHLA domain; Region: MEKHLA; pfam08670
1123863006337	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863006338	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863006339	dimer interface [polypeptide binding]; other site
1123863006340	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1123863006341	putative CheW interface [polypeptide binding]; other site
1123863006342	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1123863006343	Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltE; COG3967
1123863006344	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863006345	NAD(P) binding site [chemical binding]; other site
1123863006346	active site
1123863006347	putative choline sulfate-utilization transcription factor; Region: chol_sulf_TF; TIGR03418
1123863006348	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863006349	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863006350	dimerization interface [polypeptide binding]; other site
1123863006351	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863006352	Coenzyme A binding pocket [chemical binding]; other site
1123863006353	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1123863006354	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1123863006355	choline dehydrogenase; Validated; Region: PRK02106
1123863006356	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1123863006357	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
1123863006358	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1123863006359	NAD(P) binding site [chemical binding]; other site
1123863006360	catalytic residues [active]
1123863006361	transcriptional regulator BetI; Validated; Region: PRK00767
1123863006362	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863006363	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1123863006364	choline transport protein BetT; Provisional; Region: PRK09928
1123863006365	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863006366	putative substrate translocation pore; other site
1123863006367	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3813
1123863006368	Protein of unknown function (DUF1272); Region: DUF1272; pfam06906
1123863006369	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1123863006370	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863006371	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1123863006372	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1123863006373	mce related protein; Region: MCE; pfam02470
1123863006374	mce related protein; Region: MCE; pfam02470
1123863006375	mce related protein; Region: MCE; pfam02470
1123863006376	mce related protein; Region: MCE; pfam02470
1123863006377	mce related protein; Region: MCE; pfam02470
1123863006378	mce related protein; Region: MCE; pfam02470
1123863006379	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1123863006380	Paraquat-inducible protein A; Region: PqiA; pfam04403
1123863006381	Paraquat-inducible protein A; Region: PqiA; pfam04403
1123863006382	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1123863006383	GAF domain; Region: GAF_2; pfam13185
1123863006384	ProP expression regulator; Provisional; Region: PRK04950
1123863006385	ProQ/FINO family; Region: ProQ; pfam04352
1123863006386	carboxy-terminal protease; Provisional; Region: PRK11186
1123863006387	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1123863006388	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1123863006389	protein binding site [polypeptide binding]; other site
1123863006390	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1123863006391	Catalytic dyad [active]
1123863006392	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1123863006393	heat shock protein HtpX; Provisional; Region: PRK05457
1123863006394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863006395	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863006396	putative substrate translocation pore; other site
1123863006397	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cl03181
1123863006398	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1123863006399	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863006400	putative DNA binding site [nucleotide binding]; other site
1123863006401	putative Zn2+ binding site [ion binding]; other site
1123863006402	Bacterial transcriptional regulator; Region: IclR; pfam01614
1123863006403	YobH-like protein; Region: YobH; pfam13996
1123863006404	YebO-like protein; Region: YebO; pfam13974
1123863006405	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1123863006406	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1123863006407	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1123863006408	DNA-binding site [nucleotide binding]; DNA binding site
1123863006409	RNA-binding motif; other site
1123863006410	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1123863006411	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863006412	S-adenosylmethionine binding site [chemical binding]; other site
1123863006413	hypothetical protein; Provisional; Region: PRK02913
1123863006414	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1123863006415	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1123863006416	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1123863006417	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1123863006418	active pocket/dimerization site; other site
1123863006419	active site
1123863006420	phosphorylation site [posttranslational modification]
1123863006421	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1123863006422	active site
1123863006423	phosphorylation site [posttranslational modification]
1123863006424	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1123863006425	FOG: CBS domain [General function prediction only]; Region: COG0517
1123863006426	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1123863006427	Transporter associated domain; Region: CorC_HlyC; smart01091
1123863006428	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1123863006429	phage resistance protein; Provisional; Region: PRK10551
1123863006430	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863006431	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1123863006432	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1123863006433	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1123863006434	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1123863006435	putative active site [active]
1123863006436	putative CoA binding site [chemical binding]; other site
1123863006437	nudix motif; other site
1123863006438	metal binding site [ion binding]; metal-binding site
1123863006439	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1123863006440	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1123863006441	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1123863006442	hypothetical protein; Provisional; Region: PRK05114
1123863006443	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1123863006444	homotrimer interaction site [polypeptide binding]; other site
1123863006445	putative active site [active]
1123863006446	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1123863006447	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1123863006448	DEAD_2; Region: DEAD_2; pfam06733
1123863006449	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1123863006450	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1123863006451	Glycoprotease family; Region: Peptidase_M22; pfam00814
1123863006452	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
1123863006453	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1123863006454	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1123863006455	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1123863006456	acyl-activating enzyme (AAE) consensus motif; other site
1123863006457	putative AMP binding site [chemical binding]; other site
1123863006458	putative active site [active]
1123863006459	putative CoA binding site [chemical binding]; other site
1123863006460	ribonuclease D; Provisional; Region: PRK10829
1123863006461	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1123863006462	catalytic site [active]
1123863006463	putative active site [active]
1123863006464	putative substrate binding site [chemical binding]; other site
1123863006465	HRDC domain; Region: HRDC; pfam00570
1123863006466	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1123863006467	cell division inhibitor MinD; Provisional; Region: PRK10818
1123863006468	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1123863006469	Switch I; other site
1123863006470	Switch II; other site
1123863006471	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1123863006472	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1123863006473	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1123863006474	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1123863006475	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1123863006476	hypothetical protein; Provisional; Region: PRK10691
1123863006477	hypothetical protein; Provisional; Region: PRK05170
1123863006478	disulfide bond formation protein B; Provisional; Region: PRK01749
1123863006479	fatty acid metabolism regulator; Provisional; Region: PRK04984
1123863006480	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863006481	DNA-binding site [nucleotide binding]; DNA binding site
1123863006482	FadR C-terminal domain; Region: FadR_C; pfam07840
1123863006483	SpoVR family protein; Provisional; Region: PRK11767
1123863006484	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1123863006485	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1123863006486	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863006487	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1123863006488	alanine racemase; Reviewed; Region: dadX; PRK03646
1123863006489	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1123863006490	active site
1123863006491	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1123863006492	substrate binding site [chemical binding]; other site
1123863006493	catalytic residues [active]
1123863006494	dimer interface [polypeptide binding]; other site
1123863006495	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1123863006496	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863006497	putative substrate translocation pore; other site
1123863006498	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1123863006499	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1123863006500	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1123863006501	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1123863006502	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1123863006503	TrkA-C domain; Region: TrkA_C; pfam02080
1123863006504	Transporter associated domain; Region: CorC_HlyC; smart01091
1123863006505	hypothetical protein; Provisional; Region: PRK05325
1123863006506	PrkA family serine protein kinase; Provisional; Region: PRK15455
1123863006507	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863006508	Walker A motif; other site
1123863006509	ATP binding site [chemical binding]; other site
1123863006510	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1123863006511	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1123863006512	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1123863006513	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1123863006514	active site
1123863006515	catalytic tetrad [active]
1123863006516	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1123863006517	active site
1123863006518	phosphate binding residues; other site
1123863006519	catalytic residues [active]
1123863006520	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1123863006521	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1123863006522	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1123863006523	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1123863006524	SelR domain; Region: SelR; pfam01641
1123863006525	Protein of unknown function (DUF1315); Region: DUF1315; pfam07023
1123863006526	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1123863006527	Isochorismatase family; Region: Isochorismatase; pfam00857
1123863006528	catalytic triad [active]
1123863006529	metal binding site [ion binding]; metal-binding site
1123863006530	conserved cis-peptide bond; other site
1123863006531	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1123863006532	active site
1123863006533	homodimer interface [polypeptide binding]; other site
1123863006534	protease 4; Provisional; Region: PRK10949
1123863006535	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1123863006536	tandem repeat interface [polypeptide binding]; other site
1123863006537	oligomer interface [polypeptide binding]; other site
1123863006538	active site residues [active]
1123863006539	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1123863006540	tandem repeat interface [polypeptide binding]; other site
1123863006541	oligomer interface [polypeptide binding]; other site
1123863006542	active site residues [active]
1123863006543	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1123863006544	putative FMN binding site [chemical binding]; other site
1123863006545	DNA topoisomerase III; Provisional; Region: PRK07726
1123863006546	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1123863006547	active site
1123863006548	putative interdomain interaction site [polypeptide binding]; other site
1123863006549	putative metal-binding site [ion binding]; other site
1123863006550	putative nucleotide binding site [chemical binding]; other site
1123863006551	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1123863006552	domain I; other site
1123863006553	DNA binding groove [nucleotide binding]
1123863006554	phosphate binding site [ion binding]; other site
1123863006555	domain II; other site
1123863006556	domain III; other site
1123863006557	nucleotide binding site [chemical binding]; other site
1123863006558	catalytic site [active]
1123863006559	domain IV; other site
1123863006560	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1123863006561	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1123863006562	putative catalytic site [active]
1123863006563	putative phosphate binding site [ion binding]; other site
1123863006564	active site
1123863006565	metal binding site A [ion binding]; metal-binding site
1123863006566	DNA binding site [nucleotide binding]
1123863006567	putative AP binding site [nucleotide binding]; other site
1123863006568	putative metal binding site B [ion binding]; other site
1123863006569	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1123863006570	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1123863006571	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1123863006572	putative active site [active]
1123863006573	putative substrate binding site [chemical binding]; other site
1123863006574	putative cosubstrate binding site; other site
1123863006575	catalytic site [active]
1123863006576	hypothetical protein; Provisional; Region: PRK01617
1123863006577	SEC-C motif; Region: SEC-C; pfam02810
1123863006578	hypothetical protein; Provisional; Region: PRK10279
1123863006579	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1123863006580	active site
1123863006581	nucleophile elbow; other site
1123863006582	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863006583	active site
1123863006584	response regulator of RpoS; Provisional; Region: PRK10693
1123863006585	phosphorylation site [posttranslational modification]
1123863006586	intermolecular recognition site; other site
1123863006587	dimerization interface [polypeptide binding]; other site
1123863006588	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1123863006589	active site
1123863006590	tetramer interface; other site
1123863006591	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1123863006592	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1123863006593	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1123863006594	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1123863006595	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1123863006596	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
1123863006597	putative NAD(P) binding site [chemical binding]; other site
1123863006598	active site
1123863006599	putative substrate binding site [chemical binding]; other site
1123863006600	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1123863006601	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1123863006602	thymidine kinase; Provisional; Region: PRK04296
1123863006603	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1123863006604	ATP binding site [chemical binding]; other site
1123863006605	Walker A motif; other site
1123863006606	Walker B motif; other site
1123863006607	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1123863006608	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1123863006609	putative catalytic cysteine [active]
1123863006610	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1123863006611	putative active site [active]
1123863006612	metal binding site [ion binding]; metal-binding site
1123863006613	hypothetical protein; Provisional; Region: PRK11111
1123863006614	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1123863006615	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1123863006616	peptide binding site [polypeptide binding]; other site
1123863006617	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1123863006618	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1123863006619	peptide binding site [polypeptide binding]; other site
1123863006620	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1123863006621	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863006622	dimer interface [polypeptide binding]; other site
1123863006623	conserved gate region; other site
1123863006624	putative PBP binding loops; other site
1123863006625	ABC-ATPase subunit interface; other site
1123863006626	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1123863006627	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1123863006628	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863006629	dimer interface [polypeptide binding]; other site
1123863006630	conserved gate region; other site
1123863006631	ABC-ATPase subunit interface; other site
1123863006632	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1123863006633	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863006634	Walker A/P-loop; other site
1123863006635	ATP binding site [chemical binding]; other site
1123863006636	Q-loop/lid; other site
1123863006637	ABC transporter signature motif; other site
1123863006638	Walker B; other site
1123863006639	D-loop; other site
1123863006640	H-loop/switch region; other site
1123863006641	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1123863006642	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1123863006643	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863006644	Walker A/P-loop; other site
1123863006645	ATP binding site [chemical binding]; other site
1123863006646	Q-loop/lid; other site
1123863006647	ABC transporter signature motif; other site
1123863006648	Walker B; other site
1123863006649	D-loop; other site
1123863006650	H-loop/switch region; other site
1123863006651	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1123863006652	dsDNA-mimic protein; Reviewed; Region: PRK05094
1123863006653	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1123863006654	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1123863006655	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1123863006656	putative active site [active]
1123863006657	catalytic site [active]
1123863006658	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1123863006659	putative active site [active]
1123863006660	catalytic site [active]
1123863006661	YciI-like protein; Reviewed; Region: PRK11370
1123863006662	transport protein TonB; Provisional; Region: PRK10819
1123863006663	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1123863006664	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1123863006665	intracellular septation protein A; Reviewed; Region: PRK00259
1123863006666	hypothetical protein; Provisional; Region: PRK02868
1123863006667	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1123863006668	outer membrane protein W; Provisional; Region: PRK10959
1123863006669	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
1123863006670	BON domain; Region: BON; pfam04972
1123863006671	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1123863006672	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1123863006673	substrate binding site [chemical binding]; other site
1123863006674	active site
1123863006675	catalytic residues [active]
1123863006676	heterodimer interface [polypeptide binding]; other site
1123863006677	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1123863006678	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1123863006679	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863006680	catalytic residue [active]
1123863006681	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1123863006682	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1123863006683	active site
1123863006684	ribulose/triose binding site [chemical binding]; other site
1123863006685	phosphate binding site [ion binding]; other site
1123863006686	substrate (anthranilate) binding pocket [chemical binding]; other site
1123863006687	product (indole) binding pocket [chemical binding]; other site
1123863006688	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1123863006689	active site
1123863006690	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1123863006691	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1123863006692	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1123863006693	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1123863006694	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1123863006695	glutamine binding [chemical binding]; other site
1123863006696	catalytic triad [active]
1123863006697	anthranilate synthase component I; Provisional; Region: PRK13564
1123863006698	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1123863006699	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1123863006700	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1123863006701	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1123863006702	active site
1123863006703	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1123863006704	hypothetical protein; Provisional; Region: PRK11630
1123863006705	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1123863006706	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1123863006707	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1123863006708	RNA binding surface [nucleotide binding]; other site
1123863006709	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1123863006710	probable active site [active]
1123863006711	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
1123863006712	Citrate transporter; Region: CitMHS; pfam03600
1123863006713	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1123863006714	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
1123863006715	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1123863006716	homodimer interface [polypeptide binding]; other site
1123863006717	Walker A motif; other site
1123863006718	ATP binding site [chemical binding]; other site
1123863006719	hydroxycobalamin binding site [chemical binding]; other site
1123863006720	Walker B motif; other site
1123863006721	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1123863006722	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863006723	NAD(P) binding site [chemical binding]; other site
1123863006724	active site
1123863006725	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1123863006726	putative inner membrane peptidase; Provisional; Region: PRK11778
1123863006727	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1123863006728	tandem repeat interface [polypeptide binding]; other site
1123863006729	oligomer interface [polypeptide binding]; other site
1123863006730	active site residues [active]
1123863006731	hypothetical protein; Provisional; Region: PRK11037
1123863006732	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1123863006733	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1123863006734	active site
1123863006735	interdomain interaction site; other site
1123863006736	putative metal-binding site [ion binding]; other site
1123863006737	nucleotide binding site [chemical binding]; other site
1123863006738	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1123863006739	domain I; other site
1123863006740	DNA binding groove [nucleotide binding]
1123863006741	phosphate binding site [ion binding]; other site
1123863006742	domain II; other site
1123863006743	domain III; other site
1123863006744	nucleotide binding site [chemical binding]; other site
1123863006745	catalytic site [active]
1123863006746	domain IV; other site
1123863006747	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1123863006748	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1123863006749	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1123863006750	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1123863006751	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1123863006752	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863006753	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1123863006754	substrate binding site [chemical binding]; other site
1123863006755	putative dimerization interface [polypeptide binding]; other site
1123863006756	aconitate hydratase; Validated; Region: PRK09277
1123863006757	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1123863006758	substrate binding site [chemical binding]; other site
1123863006759	ligand binding site [chemical binding]; other site
1123863006760	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1123863006761	substrate binding site [chemical binding]; other site
1123863006762	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1123863006763	dimerization interface [polypeptide binding]; other site
1123863006764	active site
1123863006765	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1123863006766	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1123863006767	active site
1123863006768	Predicted membrane protein [Function unknown]; Region: COG3771
1123863006769	tetratricopeptide repeat protein; Provisional; Region: PRK11788
1123863006770	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1123863006771	TPR motif; other site
1123863006772	binding surface
1123863006773	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1123863006774	binding surface
1123863006775	TPR motif; other site
1123863006776	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1123863006777	active site
1123863006778	dimer interface [polypeptide binding]; other site
1123863006779	translation initiation factor Sui1; Validated; Region: PRK06824
1123863006780	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1123863006781	putative rRNA binding site [nucleotide binding]; other site
1123863006782	lipoprotein; Provisional; Region: PRK10540
1123863006783	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1123863006784	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1123863006785	intersubunit interface [polypeptide binding]; other site
1123863006786	active site
1123863006787	Zn2+ binding site [ion binding]; other site
1123863006788	enoyl-CoA hydratase; Validated; Region: PRK08788
1123863006789	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1123863006790	substrate binding site [chemical binding]; other site
1123863006791	oxyanion hole (OAH) forming residues; other site
1123863006792	trimer interface [polypeptide binding]; other site
1123863006793	RNase II stability modulator; Provisional; Region: PRK10060
1123863006794	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863006795	putative active site [active]
1123863006796	heme pocket [chemical binding]; other site
1123863006797	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863006798	metal binding site [ion binding]; metal-binding site
1123863006799	active site
1123863006800	I-site; other site
1123863006801	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863006802	Uncharacterized small protein [Function unknown]; Region: COG2879
1123863006803	carbon starvation protein A; Provisional; Region: PRK15015
1123863006804	Carbon starvation protein CstA; Region: CstA; pfam02554
1123863006805	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1123863006806	exoribonuclease II; Provisional; Region: PRK05054
1123863006807	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1123863006808	RNB domain; Region: RNB; pfam00773
1123863006809	S1 RNA binding domain; Region: S1; pfam00575
1123863006810	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
1123863006811	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1123863006812	putative molybdopterin cofactor binding site [chemical binding]; other site
1123863006813	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1123863006814	putative molybdopterin cofactor binding site; other site
1123863006815	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1123863006816	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1123863006817	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1123863006818	active site turn [active]
1123863006819	phosphorylation site [posttranslational modification]
1123863006820	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863006821	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1123863006822	dimerization interface [polypeptide binding]; other site
1123863006823	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950; cl17731
1123863006824	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1123863006825	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1123863006826	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1123863006827	NAD binding site [chemical binding]; other site
1123863006828	homotetramer interface [polypeptide binding]; other site
1123863006829	homodimer interface [polypeptide binding]; other site
1123863006830	substrate binding site [chemical binding]; other site
1123863006831	active site
1123863006832	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1123863006833	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863006834	Walker A/P-loop; other site
1123863006835	ATP binding site [chemical binding]; other site
1123863006836	Q-loop/lid; other site
1123863006837	ABC transporter signature motif; other site
1123863006838	Walker B; other site
1123863006839	D-loop; other site
1123863006840	H-loop/switch region; other site
1123863006841	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1123863006842	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1123863006843	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863006844	Walker A/P-loop; other site
1123863006845	ATP binding site [chemical binding]; other site
1123863006846	Q-loop/lid; other site
1123863006847	ABC transporter signature motif; other site
1123863006848	Walker B; other site
1123863006849	D-loop; other site
1123863006850	H-loop/switch region; other site
1123863006851	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1123863006852	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1123863006853	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863006854	dimer interface [polypeptide binding]; other site
1123863006855	conserved gate region; other site
1123863006856	putative PBP binding loops; other site
1123863006857	ABC-ATPase subunit interface; other site
1123863006858	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1123863006859	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863006860	dimer interface [polypeptide binding]; other site
1123863006861	conserved gate region; other site
1123863006862	putative PBP binding loops; other site
1123863006863	ABC-ATPase subunit interface; other site
1123863006864	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1123863006865	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1123863006866	peptide binding site [polypeptide binding]; other site
1123863006867	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1123863006868	Coenzyme A binding pocket [chemical binding]; other site
1123863006869	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1123863006870	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863006871	Walker A motif; other site
1123863006872	ATP binding site [chemical binding]; other site
1123863006873	Walker B motif; other site
1123863006874	arginine finger; other site
1123863006875	phage shock protein PspA; Provisional; Region: PRK10698
1123863006876	phage shock protein B; Provisional; Region: pspB; PRK09458
1123863006877	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1123863006878	phage shock protein C; Region: phageshock_pspC; TIGR02978
1123863006879	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1123863006880	Predicted ATPase [General function prediction only]; Region: COG3106
1123863006881	hypothetical protein; Provisional; Region: PRK05415
1123863006882	Domain of unknown function (DUF697); Region: DUF697; cl12064
1123863006883	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1123863006884	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1123863006885	putative aromatic amino acid binding site; other site
1123863006886	PAS domain; Region: PAS; smart00091
1123863006887	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863006888	Walker A motif; other site
1123863006889	ATP binding site [chemical binding]; other site
1123863006890	Walker B motif; other site
1123863006891	arginine finger; other site
1123863006892	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1123863006893	dimer interface [polypeptide binding]; other site
1123863006894	catalytic triad [active]
1123863006895	peroxidatic and resolving cysteines [active]
1123863006896	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1123863006897	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1123863006898	active site
1123863006899	murein peptide amidase A; Provisional; Region: PRK10602
1123863006900	active site
1123863006901	Zn binding site [ion binding]; other site
1123863006902	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1123863006903	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1123863006904	peptide binding site [polypeptide binding]; other site
1123863006905	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1123863006906	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1123863006907	Cl binding site [ion binding]; other site
1123863006908	oligomer interface [polypeptide binding]; other site
1123863006909	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1123863006910	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1123863006911	Ligand Binding Site [chemical binding]; other site
1123863006912	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
1123863006913	MgtC family; Region: MgtC; pfam02308
1123863006914	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1123863006915	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1123863006916	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1123863006917	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1123863006918	putative ligand binding site [chemical binding]; other site
1123863006919	putative NAD binding site [chemical binding]; other site
1123863006920	catalytic site [active]
1123863006921	hypothetical protein; Provisional; Region: PRK10695
1123863006922	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1123863006923	Protein of unknown function (DUF1318); Region: DUF1318; pfam07027
1123863006924	azoreductase; Reviewed; Region: PRK00170
1123863006925	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1123863006926	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1123863006927	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863006928	ATP binding site [chemical binding]; other site
1123863006929	putative Mg++ binding site [ion binding]; other site
1123863006930	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863006931	nucleotide binding region [chemical binding]; other site
1123863006932	ATP-binding site [chemical binding]; other site
1123863006933	Helicase associated domain (HA2); Region: HA2; pfam04408
1123863006934	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1123863006935	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1123863006936	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1123863006937	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1123863006938	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1123863006939	active site
1123863006940	Zn binding site [ion binding]; other site
1123863006941	sensor protein RstB; Provisional; Region: PRK10604
1123863006942	HAMP domain; Region: HAMP; pfam00672
1123863006943	dimerization interface [polypeptide binding]; other site
1123863006944	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863006945	dimer interface [polypeptide binding]; other site
1123863006946	phosphorylation site [posttranslational modification]
1123863006947	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863006948	ATP binding site [chemical binding]; other site
1123863006949	Mg2+ binding site [ion binding]; other site
1123863006950	G-X-G motif; other site
1123863006951	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1123863006952	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863006953	active site
1123863006954	phosphorylation site [posttranslational modification]
1123863006955	intermolecular recognition site; other site
1123863006956	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863006957	DNA binding site [nucleotide binding]
1123863006958	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1123863006959	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863006960	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863006961	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863006962	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1123863006963	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1123863006964	ligand binding site [chemical binding]; other site
1123863006965	homodimer interface [polypeptide binding]; other site
1123863006966	NAD(P) binding site [chemical binding]; other site
1123863006967	trimer interface B [polypeptide binding]; other site
1123863006968	trimer interface A [polypeptide binding]; other site
1123863006969	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1123863006970	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1123863006971	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1123863006972	universal stress protein UspE; Provisional; Region: PRK11175
1123863006973	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1123863006974	Ligand Binding Site [chemical binding]; other site
1123863006975	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1123863006976	Ligand Binding Site [chemical binding]; other site
1123863006977	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1123863006978	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1123863006979	ligand binding site [chemical binding]; other site
1123863006980	flexible hinge region; other site
1123863006981	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1123863006982	putative switch regulator; other site
1123863006983	non-specific DNA interactions [nucleotide binding]; other site
1123863006984	DNA binding site [nucleotide binding]
1123863006985	sequence specific DNA binding site [nucleotide binding]; other site
1123863006986	putative cAMP binding site [chemical binding]; other site
1123863006987	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1123863006988	Smr domain; Region: Smr; pfam01713
1123863006989	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1123863006990	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863006991	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863006992	dimerization interface [polypeptide binding]; other site
1123863006993	benzoate transport; Region: 2A0115; TIGR00895
1123863006994	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863006995	putative substrate translocation pore; other site
1123863006996	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863006997	Domain of unknown function (DUF1338); Region: DUF1338; pfam07063
1123863006998	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1123863006999	Predicted membrane protein [Function unknown]; Region: COG2259
1123863007000	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1123863007001	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1123863007002	substrate binding pocket [chemical binding]; other site
1123863007003	catalytic triad [active]
1123863007004	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1123863007005	HAMP domain; Region: HAMP; pfam00672
1123863007006	dimerization interface [polypeptide binding]; other site
1123863007007	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863007008	dimer interface [polypeptide binding]; other site
1123863007009	putative CheW interface [polypeptide binding]; other site
1123863007010	peptidase T; Region: peptidase-T; TIGR01882
1123863007011	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1123863007012	metal binding site [ion binding]; metal-binding site
1123863007013	dimer interface [polypeptide binding]; other site
1123863007014	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1123863007015	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1123863007016	peptide binding site [polypeptide binding]; other site
1123863007017	hypothetical protein; Provisional; Region: PRK11019
1123863007018	putative arabinose transporter; Provisional; Region: PRK03545
1123863007019	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007020	putative substrate translocation pore; other site
1123863007021	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1123863007022	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007023	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863007024	putative substrate translocation pore; other site
1123863007025	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1123863007026	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863007027	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1123863007028	dimerization interface [polypeptide binding]; other site
1123863007029	substrate binding pocket [chemical binding]; other site
1123863007030	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1123863007031	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1123863007032	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1123863007033	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1123863007034	AAA domain; Region: AAA_26; pfam13500
1123863007035	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1123863007036	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1123863007037	Walker A/P-loop; other site
1123863007038	ATP binding site [chemical binding]; other site
1123863007039	Q-loop/lid; other site
1123863007040	ABC transporter signature motif; other site
1123863007041	Walker B; other site
1123863007042	D-loop; other site
1123863007043	H-loop/switch region; other site
1123863007044	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
1123863007045	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863007046	dimer interface [polypeptide binding]; other site
1123863007047	conserved gate region; other site
1123863007048	ABC-ATPase subunit interface; other site
1123863007049	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1123863007050	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863007051	dimer interface [polypeptide binding]; other site
1123863007052	conserved gate region; other site
1123863007053	putative PBP binding loops; other site
1123863007054	ABC-ATPase subunit interface; other site
1123863007055	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863007056	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007057	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1123863007058	hypothetical protein; Provisional; Region: PRK13659
1123863007059	hypothetical protein; Provisional; Region: PRK02237
1123863007060	malonic semialdehyde reductase; Provisional; Region: PRK10538
1123863007061	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1123863007062	putative NAD(P) binding site [chemical binding]; other site
1123863007063	homodimer interface [polypeptide binding]; other site
1123863007064	homotetramer interface [polypeptide binding]; other site
1123863007065	active site
1123863007066	guanine deaminase; Provisional; Region: PRK09228
1123863007067	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1123863007068	active site
1123863007069	xanthine dehydrogenase, small subunit; Region: xanthine_xdhA; TIGR02963
1123863007070	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1123863007071	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1123863007072	xanthine dehydrogenase, molybdopterin binding subunit; Region: xanthine_xdhB; TIGR02965
1123863007073	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1123863007074	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1123863007075	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1123863007076	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
1123863007077	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1123863007078	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1123863007079	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1123863007080	active site
1123863007081	Zn binding site [ion binding]; other site
1123863007082	hypothetical protein; Provisional; Region: PRK07236
1123863007083	FAD binding domain; Region: FAD_binding_3; pfam01494
1123863007084	potential frameshift: common BLAST hit: gi|308186874|ref|YP_003931005.1| glycogen synthase 2
1123863007085	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1123863007086	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1123863007087	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
1123863007088	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1123863007089	short chain dehydrogenase; Provisional; Region: PRK06701
1123863007090	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1123863007091	NAD binding site [chemical binding]; other site
1123863007092	metal binding site [ion binding]; metal-binding site
1123863007093	active site
1123863007094	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1123863007095	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1123863007096	DNA binding residues [nucleotide binding]
1123863007097	dimerization interface [polypeptide binding]; other site
1123863007098	Autoinducer synthetase; Region: Autoind_synth; pfam00765
1123863007099	putative symporter YagG; Provisional; Region: PRK09669
1123863007100	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007101	putative substrate translocation pore; other site
1123863007102	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1123863007103	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1123863007104	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1123863007105	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863007106	Coenzyme A binding pocket [chemical binding]; other site
1123863007107	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1123863007108	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863007109	non-specific DNA binding site [nucleotide binding]; other site
1123863007110	salt bridge; other site
1123863007111	sequence-specific DNA binding site [nucleotide binding]; other site
1123863007112	HipA N-terminal domain; Region: Couple_hipA; pfam13657
1123863007113	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
1123863007114	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1123863007115	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1123863007116	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1123863007117	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1123863007118	potassium uptake protein; Region: kup; TIGR00794
1123863007119	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863007120	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863007121	dimer interface [polypeptide binding]; other site
1123863007122	putative CheW interface [polypeptide binding]; other site
1123863007123	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5343
1123863007124	Anti-sigma-K factor rskA; Region: RskA; pfam10099
1123863007125	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1123863007126	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863007127	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1123863007128	DNA binding residues [nucleotide binding]
1123863007129	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
1123863007130	Fasciclin domain; Region: Fasciclin; pfam02469
1123863007131	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1123863007132	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863007133	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863007134	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863007135	dimerization interface [polypeptide binding]; other site
1123863007136	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
1123863007137	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 1; Region: PLPDE_III_DSD_D-TA_like_1; cd06812
1123863007138	dimer interface [polypeptide binding]; other site
1123863007139	active site
1123863007140	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1123863007141	substrate binding site [chemical binding]; other site
1123863007142	catalytic residue [active]
1123863007143	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1123863007144	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1123863007145	NAD(P) binding site [chemical binding]; other site
1123863007146	catalytic residues [active]
1123863007147	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1123863007148	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1123863007149	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1123863007150	homotrimer interaction site [polypeptide binding]; other site
1123863007151	putative active site [active]
1123863007152	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1123863007153	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863007154	DNA-binding site [nucleotide binding]; DNA binding site
1123863007155	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1123863007156	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1123863007157	DNA-binding site [nucleotide binding]; DNA binding site
1123863007158	FCD domain; Region: FCD; pfam07729
1123863007159	hypothetical protein; Provisional; Region: PRK06102
1123863007160	Amidase; Region: Amidase; cl11426
1123863007161	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1123863007162	active site
1123863007163	catalytic site [active]
1123863007164	Zn binding site [ion binding]; other site
1123863007165	tetramer interface [polypeptide binding]; other site
1123863007166	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1123863007167	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007168	benzoate transport; Region: 2A0115; TIGR00895
1123863007169	putative substrate translocation pore; other site
1123863007170	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863007171	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1123863007172	NAD(P) binding site [chemical binding]; other site
1123863007173	active site
1123863007174	short chain dehydrogenase; Provisional; Region: PRK12939
1123863007175	classical (c) SDRs; Region: SDR_c; cd05233
1123863007176	NAD(P) binding site [chemical binding]; other site
1123863007177	active site
1123863007178	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1123863007179	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1123863007180	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1123863007181	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1123863007182	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1123863007183	nudix motif; other site
1123863007184	Winged helix-turn helix; Region: HTH_29; pfam13551
1123863007185	Homeodomain-like domain; Region: HTH_32; pfam13565
1123863007186	NlpC/P60 family; Region: NLPC_P60; pfam00877
1123863007187	magnesium transport protein MgtC; Provisional; Region: PRK15385
1123863007188	MgtC family; Region: MgtC; pfam02308
1123863007189	putative oxidoreductase; Provisional; Region: PRK09939
1123863007190	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1123863007191	putative molybdopterin cofactor binding site [chemical binding]; other site
1123863007192	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1123863007193	putative molybdopterin cofactor binding site; other site
1123863007194	Uncharacterized protein conserved in bacteria (DUF2256); Region: DUF2256; pfam10013
1123863007195	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
1123863007196	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1123863007197	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1123863007198	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863007199	Coenzyme A binding pocket [chemical binding]; other site
1123863007200	potential frameshift: common BLAST hit: gi|291617473|ref|YP_003520215.1| Fsr
1123863007201	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007202	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863007203	putative substrate translocation pore; other site
1123863007204	transcriptional regulator MalT; Provisional; Region: PRK04841
1123863007205	AAA ATPase domain; Region: AAA_16; pfam13191
1123863007206	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1123863007207	DNA binding residues [nucleotide binding]
1123863007208	dimerization interface [polypeptide binding]; other site
1123863007209	maltodextrin phosphorylase; Provisional; Region: PRK14985
1123863007210	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1123863007211	active site pocket [active]
1123863007212	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1123863007213	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1123863007214	Helix-turn-helix domain; Region: HTH_18; pfam12833
1123863007215	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863007216	Predicted dienelactone hydrolase [General function prediction only]; Region: COG4188
1123863007217	PGAP1-like protein; Region: PGAP1; pfam07819
1123863007218	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1123863007219	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1123863007220	trimer interface; other site
1123863007221	sugar binding site [chemical binding]; other site
1123863007222	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1123863007223	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1123863007224	Walker A/P-loop; other site
1123863007225	ATP binding site [chemical binding]; other site
1123863007226	Q-loop/lid; other site
1123863007227	ABC transporter signature motif; other site
1123863007228	Walker B; other site
1123863007229	D-loop; other site
1123863007230	H-loop/switch region; other site
1123863007231	TOBE domain; Region: TOBE_2; pfam08402
1123863007232	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1123863007233	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1123863007234	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863007235	dimer interface [polypeptide binding]; other site
1123863007236	conserved gate region; other site
1123863007237	putative PBP binding loops; other site
1123863007238	ABC-ATPase subunit interface; other site
1123863007239	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1123863007240	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863007241	dimer interface [polypeptide binding]; other site
1123863007242	conserved gate region; other site
1123863007243	putative PBP binding loops; other site
1123863007244	ABC-ATPase subunit interface; other site
1123863007245	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1123863007246	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863007247	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
1123863007248	Alkaline phosphatase homologues; Region: alkPPc; smart00098
1123863007249	active site
1123863007250	dimer interface [polypeptide binding]; other site
1123863007251	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863007252	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1123863007253	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1123863007254	active site
1123863007255	FMN binding site [chemical binding]; other site
1123863007256	substrate binding site [chemical binding]; other site
1123863007257	homotetramer interface [polypeptide binding]; other site
1123863007258	catalytic residue [active]
1123863007259	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863007260	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1123863007261	active site
1123863007262	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1123863007263	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1123863007264	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1123863007265	Xanthomonas XOO_2897-like deaminase; Region: XOO_2897-deam; pfam14440
1123863007266	Bacteriorhodopsin-like protein; Region: Bac_rhodopsin; smart01021
1123863007267	Bacteriorhodopsin-like protein; Region: Bac_rhodopsin; cl02333
1123863007268	beta-carotene 15,15'-monooxygenase, Brp/Blh family; Region: blh_monoox; TIGR03753
1123863007269	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1123863007270	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863007271	dimerization interface [polypeptide binding]; other site
1123863007272	putative DNA binding site [nucleotide binding]; other site
1123863007273	putative Zn2+ binding site [ion binding]; other site
1123863007274	arsenical pump membrane protein; Provisional; Region: PRK15445
1123863007275	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1123863007276	transmembrane helices; other site
1123863007277	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1123863007278	ArsC family; Region: ArsC; pfam03960
1123863007279	catalytic residues [active]
1123863007280	M20 Peptidase Aminoacylase 1 amhX_like subfamily; Region: M20_Acy1_amhX_like; cd08018
1123863007281	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1123863007282	metal binding site [ion binding]; metal-binding site
1123863007283	putative dimer interface [polypeptide binding]; other site
1123863007284	hypothetical protein; Provisional; Region: PRK10519
1123863007285	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1123863007286	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863007287	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863007288	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_5; cd08426
1123863007289	putative dimerization interface [polypeptide binding]; other site
1123863007290	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1123863007291	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863007292	NAD(P) binding site [chemical binding]; other site
1123863007293	active site
1123863007294	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863007295	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863007296	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1123863007297	putative effector binding pocket; other site
1123863007298	putative dimerization interface [polypeptide binding]; other site
1123863007299	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863007300	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1123863007301	active site
1123863007302	metal binding site [ion binding]; metal-binding site
1123863007303	maltose O-acetyltransferase; Provisional; Region: PRK10092
1123863007304	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1123863007305	active site
1123863007306	substrate binding site [chemical binding]; other site
1123863007307	trimer interface [polypeptide binding]; other site
1123863007308	CoA binding site [chemical binding]; other site
1123863007309	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863007310	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863007311	DNA binding site [nucleotide binding]
1123863007312	domain linker motif; other site
1123863007313	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1123863007314	dimerization interface [polypeptide binding]; other site
1123863007315	ligand binding site [chemical binding]; other site
1123863007316	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863007317	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863007318	substrate binding pocket [chemical binding]; other site
1123863007319	membrane-bound complex binding site; other site
1123863007320	hinge residues; other site
1123863007321	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863007322	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863007323	dimer interface [polypeptide binding]; other site
1123863007324	conserved gate region; other site
1123863007325	putative PBP binding loops; other site
1123863007326	ABC-ATPase subunit interface; other site
1123863007327	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1123863007328	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863007329	Walker A/P-loop; other site
1123863007330	ATP binding site [chemical binding]; other site
1123863007331	Q-loop/lid; other site
1123863007332	ABC transporter signature motif; other site
1123863007333	Walker B; other site
1123863007334	D-loop; other site
1123863007335	H-loop/switch region; other site
1123863007336	putative oxidoreductase; Provisional; Region: PRK11579
1123863007337	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863007338	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1123863007339	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1123863007340	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1123863007341	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1123863007342	NAD(P) binding site [chemical binding]; other site
1123863007343	substrate binding site [chemical binding]; other site
1123863007344	dimer interface [polypeptide binding]; other site
1123863007345	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863007346	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1123863007347	substrate binding site [chemical binding]; other site
1123863007348	ATP binding site [chemical binding]; other site
1123863007349	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
1123863007350	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863007351	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1123863007352	putative active site [active]
1123863007353	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863007354	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863007355	TM-ABC transporter signature motif; other site
1123863007356	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863007357	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863007358	Walker A/P-loop; other site
1123863007359	ATP binding site [chemical binding]; other site
1123863007360	Q-loop/lid; other site
1123863007361	ABC transporter signature motif; other site
1123863007362	Walker B; other site
1123863007363	D-loop; other site
1123863007364	H-loop/switch region; other site
1123863007365	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863007366	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
1123863007367	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1123863007368	ligand binding site [chemical binding]; other site
1123863007369	dimerization interface [polypeptide binding]; other site
1123863007370	zinc binding site [ion binding]; other site
1123863007371	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1123863007372	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1123863007373	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1123863007374	tetramer interface [polypeptide binding]; other site
1123863007375	heme binding pocket [chemical binding]; other site
1123863007376	NADPH binding site [chemical binding]; other site
1123863007377	phosphonate metabolim protein, transferase hexapeptide repeat family; Region: phn_thr-fam; TIGR03308
1123863007378	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1123863007379	trimer interface [polypeptide binding]; other site
1123863007380	active site
1123863007381	substrate binding site [chemical binding]; other site
1123863007382	CoA binding site [chemical binding]; other site
1123863007383	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
1123863007384	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
1123863007385	AAA domain; Region: AAA_17; pfam13207
1123863007386	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863007387	active site
1123863007388	phosphorylation site [posttranslational modification]
1123863007389	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1123863007390	intersubunit interface [polypeptide binding]; other site
1123863007391	active site
1123863007392	zinc binding site [ion binding]; other site
1123863007393	Na+ binding site [ion binding]; other site
1123863007394	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1123863007395	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1123863007396	active site
1123863007397	P-loop; other site
1123863007398	phosphorylation site [posttranslational modification]
1123863007399	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
1123863007400	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1123863007401	active site
1123863007402	ADP/pyrophosphate binding site [chemical binding]; other site
1123863007403	dimerization interface [polypeptide binding]; other site
1123863007404	allosteric effector site; other site
1123863007405	fructose-1,6-bisphosphate binding site; other site
1123863007406	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1123863007407	coenzyme PQQ biosynthesis probable peptidase PqqF; Region: PQQ_syn_pqqF; TIGR02110
1123863007408	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1123863007409	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1123863007410	pyrroloquinoline quinone biosynthesis protein PqqE; Provisional; Region: PRK05301
1123863007411	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863007412	FeS/SAM binding site; other site
1123863007413	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1123863007414	pyrroloquinoline quinone biosynthesis protein PqqC; Provisional; Region: PRK05157
1123863007415	pyrroloquinoline quinone biosynthesis protein PqqB; Provisional; Region: PRK05184
1123863007416	coenzyme PQQ biosynthesis protein B; Region: PQQ_syn_pqqB; TIGR02108
1123863007417	coenzyme PQQ synthesis protein PqqA; Provisional; Region: pqqA; PRK00284
1123863007418	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1123863007419	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1123863007420	active site
1123863007421	dimer interface [polypeptide binding]; other site
1123863007422	2-isopropylmalate synthase; Validated; Region: PRK03739
1123863007423	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
1123863007424	active site
1123863007425	catalytic residues [active]
1123863007426	metal binding site [ion binding]; metal-binding site
1123863007427	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1123863007428	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1123863007429	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1123863007430	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863007431	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1123863007432	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1123863007433	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1123863007434	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863007435	N-terminal plug; other site
1123863007436	ligand-binding site [chemical binding]; other site
1123863007437	Isochorismatase family; Region: Isochorismatase; pfam00857
1123863007438	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1123863007439	catalytic triad [active]
1123863007440	conserved cis-peptide bond; other site
1123863007441	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1123863007442	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863007443	non-specific DNA binding site [nucleotide binding]; other site
1123863007444	salt bridge; other site
1123863007445	sequence-specific DNA binding site [nucleotide binding]; other site
1123863007446	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1123863007447	benzoate transporter; Region: benE; TIGR00843
1123863007448	Virulence factor SrfB; Region: SrfB; pfam07520
1123863007449	Putative bacterial virulence factor; Region: Virul_Fac; pfam10139
1123863007450	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it, thus inhibiting its potentially lethal RNase activity inside the...; Region: Barstar_like; cl01048
1123863007451	RNAase interaction site [polypeptide binding]; other site
1123863007452	microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential  for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th,  Pb, N1, and Ms) and...; Region: microbial_RNases; cl00212
1123863007453	active site
1123863007454	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1123863007455	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863007456	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1123863007457	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863007458	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863007459	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1123863007460	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1123863007461	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1123863007462	catalytic site [active]
1123863007463	Predicted transcriptional regulator [Transcription]; Region: COG1959
1123863007464	Transcriptional regulator; Region: Rrf2; pfam02082
1123863007465	Transcriptional regulator; Region: Rrf2; cl17282
1123863007466	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863007467	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007468	putative substrate translocation pore; other site
1123863007469	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1123863007470	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1123863007471	Class II fumarases; Region: Fumarase_classII; cd01362
1123863007472	active site
1123863007473	tetramer interface [polypeptide binding]; other site
1123863007474	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1123863007475	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1123863007476	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1123863007477	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1123863007478	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1123863007479	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1123863007480	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1123863007481	active site
1123863007482	purine riboside binding site [chemical binding]; other site
1123863007483	putative oxidoreductase; Provisional; Region: PRK11579
1123863007484	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863007485	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1123863007486	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1123863007487	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1123863007488	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863007489	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863007490	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863007491	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863007492	TM-ABC transporter signature motif; other site
1123863007493	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
1123863007494	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863007495	Walker A/P-loop; other site
1123863007496	ATP binding site [chemical binding]; other site
1123863007497	Q-loop/lid; other site
1123863007498	ABC transporter signature motif; other site
1123863007499	Walker B; other site
1123863007500	D-loop; other site
1123863007501	H-loop/switch region; other site
1123863007502	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863007503	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1123863007504	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
1123863007505	ligand binding site [chemical binding]; other site
1123863007506	ribulokinase; Provisional; Region: PRK04123
1123863007507	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1123863007508	N- and C-terminal domain interface [polypeptide binding]; other site
1123863007509	active site
1123863007510	MgATP binding site [chemical binding]; other site
1123863007511	catalytic site [active]
1123863007512	metal binding site [ion binding]; metal-binding site
1123863007513	carbohydrate binding site [chemical binding]; other site
1123863007514	homodimer interface [polypeptide binding]; other site
1123863007515	L-arabinose isomerase; Provisional; Region: PRK02929
1123863007516	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1123863007517	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1123863007518	trimer interface [polypeptide binding]; other site
1123863007519	putative substrate binding site [chemical binding]; other site
1123863007520	putative metal binding site [ion binding]; other site
1123863007521	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863007522	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1123863007523	NAD(P) binding site [chemical binding]; other site
1123863007524	active site
1123863007525	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863007526	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863007527	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_1; cd08460
1123863007528	putative substrate binding pocket [chemical binding]; other site
1123863007529	putative dimerization interface [polypeptide binding]; other site
1123863007530	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1123863007531	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1123863007532	active site
1123863007533	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1123863007534	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1123863007535	Protein of unknown function (DUF1470); Region: DUF1470; pfam07336
1123863007536	CGNR zinc finger; Region: zf-CGNR; pfam11706
1123863007537	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1123863007538	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1123863007539	DNA-binding site [nucleotide binding]; DNA binding site
1123863007540	RNA-binding motif; other site
1123863007541	2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428
1123863007542	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
1123863007543	Phosphotransferase enzyme family; Region: APH; pfam01636
1123863007544	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1123863007545	active site
1123863007546	ATP binding site [chemical binding]; other site
1123863007547	substrate binding site [chemical binding]; other site
1123863007548	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
1123863007549	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863007550	inhibitor-cofactor binding pocket; inhibition site
1123863007551	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863007552	catalytic residue [active]
1123863007553	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1123863007554	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863007555	putative DNA binding site [nucleotide binding]; other site
1123863007556	putative Zn2+ binding site [ion binding]; other site
1123863007557	AsnC family; Region: AsnC_trans_reg; pfam01037
1123863007558	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1123863007559	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1123863007560	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1123863007561	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1123863007562	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1123863007563	atypical (a) SDRs, subgroup 7; Region: SDR_a7; cd05262
1123863007564	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1123863007565	putative NAD(P) binding site [chemical binding]; other site
1123863007566	Cupin; Region: Cupin_6; pfam12852
1123863007567	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863007568	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1123863007569	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863007570	Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]; Region: CodB; COG1457
1123863007571	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1123863007572	Na binding site [ion binding]; other site
1123863007573	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1123863007574	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1123863007575	amidase catalytic site [active]
1123863007576	Zn binding residues [ion binding]; other site
1123863007577	substrate binding site [chemical binding]; other site
1123863007578	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1123863007579	putative fimbrial chaperone protein; Provisional; Region: PRK09918
1123863007580	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863007581	PapC N-terminal domain; Region: PapC_N; pfam13954
1123863007582	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1123863007583	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1123863007584	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863007585	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1123863007586	DNA binding site [nucleotide binding]
1123863007587	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863007588	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863007589	metal binding site [ion binding]; metal-binding site
1123863007590	active site
1123863007591	I-site; other site
1123863007592	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863007593	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863007594	TM-ABC transporter signature motif; other site
1123863007595	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863007596	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863007597	TM-ABC transporter signature motif; other site
1123863007598	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863007599	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863007600	Walker A/P-loop; other site
1123863007601	ATP binding site [chemical binding]; other site
1123863007602	Q-loop/lid; other site
1123863007603	ABC transporter signature motif; other site
1123863007604	Walker B; other site
1123863007605	D-loop; other site
1123863007606	H-loop/switch region; other site
1123863007607	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863007608	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
1123863007609	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1123863007610	putative ligand binding site [chemical binding]; other site
1123863007611	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1123863007612	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1123863007613	electron transport complex protein RsxA; Provisional; Region: PRK05151
1123863007614	electron transport complex protein RnfB; Provisional; Region: PRK05113
1123863007615	Putative Fe-S cluster; Region: FeS; cl17515
1123863007616	4Fe-4S binding domain; Region: Fer4; pfam00037
1123863007617	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1123863007618	SLBB domain; Region: SLBB; pfam10531
1123863007619	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1123863007620	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1123863007621	electron transport complex protein RnfG; Validated; Region: PRK01908
1123863007622	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1123863007623	endonuclease III; Provisional; Region: PRK10702
1123863007624	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1123863007625	minor groove reading motif; other site
1123863007626	helix-hairpin-helix signature motif; other site
1123863007627	substrate binding pocket [chemical binding]; other site
1123863007628	active site
1123863007629	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1123863007630	hypothetical protein; Validated; Region: PRK06186
1123863007631	conserved cys residue [active]
1123863007632	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1123863007633	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007634	putative substrate translocation pore; other site
1123863007635	glutathionine S-transferase; Provisional; Region: PRK10542
1123863007636	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1123863007637	C-terminal domain interface [polypeptide binding]; other site
1123863007638	GSH binding site (G-site) [chemical binding]; other site
1123863007639	dimer interface [polypeptide binding]; other site
1123863007640	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1123863007641	dimer interface [polypeptide binding]; other site
1123863007642	N-terminal domain interface [polypeptide binding]; other site
1123863007643	substrate binding pocket (H-site) [chemical binding]; other site
1123863007644	pyridoxamine kinase; Validated; Region: PRK05756
1123863007645	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1123863007646	dimer interface [polypeptide binding]; other site
1123863007647	pyridoxal binding site [chemical binding]; other site
1123863007648	ATP binding site [chemical binding]; other site
1123863007649	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1123863007650	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1123863007651	active site
1123863007652	HIGH motif; other site
1123863007653	dimer interface [polypeptide binding]; other site
1123863007654	KMSKS motif; other site
1123863007655	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1123863007656	RNA binding surface [nucleotide binding]; other site
1123863007657	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1123863007658	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1123863007659	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1123863007660	lysozyme inhibitor; Provisional; Region: PRK11372
1123863007661	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1123863007662	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1123863007663	active site
1123863007664	homotetramer interface [polypeptide binding]; other site
1123863007665	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1123863007666	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1123863007667	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12698
1123863007668	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1123863007669	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1123863007670	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863007671	chaperone protein HchA; Provisional; Region: PRK04155
1123863007672	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1123863007673	conserved cys residue [active]
1123863007674	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1123863007675	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1123863007676	active site
1123863007677	DNA binding site [nucleotide binding]
1123863007678	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1123863007679	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1123863007680	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1123863007681	Catalytic site [active]
1123863007682	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
1123863007683	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1123863007684	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863007685	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863007686	dimerization interface [polypeptide binding]; other site
1123863007687	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1123863007688	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863007689	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP); Region: GATase1_ScBLP_like; cd03144
1123863007690	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1123863007691	conserved cys residue [active]
1123863007692	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1123863007693	UV-endonuclease UvdE; Region: UvdE; cl10036
1123863007694	hydroperoxidase II; Provisional; Region: katE; PRK11249
1123863007695	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1123863007696	tetramer interface [polypeptide binding]; other site
1123863007697	heme binding pocket [chemical binding]; other site
1123863007698	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1123863007699	domain interactions; other site
1123863007700	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1123863007701	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1123863007702	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1123863007703	catalytic site [active]
1123863007704	active site
1123863007705	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1123863007706	malto-oligosyltrehalose synthase; Region: trehalose_TreY; TIGR02401
1123863007707	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1123863007708	active site
1123863007709	catalytic site [active]
1123863007710	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1123863007711	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1123863007712	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1123863007713	active site
1123863007714	catalytic site [active]
1123863007715	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1123863007716	classical (c) SDRs; Region: SDR_c; cd05233
1123863007717	NAD(P) binding site [chemical binding]; other site
1123863007718	active site
1123863007719	Sensors of blue-light using FAD; Region: BLUF; pfam04940
1123863007720	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863007721	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
1123863007722	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1123863007723	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1123863007724	transcriptional regulator SlyA; Provisional; Region: PRK03573
1123863007725	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1123863007726	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1123863007727	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1123863007728	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863007729	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863007730	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1123863007731	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1123863007732	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1123863007733	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1123863007734	E-class dimer interface [polypeptide binding]; other site
1123863007735	P-class dimer interface [polypeptide binding]; other site
1123863007736	active site
1123863007737	Cu2+ binding site [ion binding]; other site
1123863007738	Zn2+ binding site [ion binding]; other site
1123863007739	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1123863007740	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1123863007741	active site
1123863007742	catalytic tetrad [active]
1123863007743	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863007744	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1123863007745	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863007746	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1123863007747	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1123863007748	FMN binding site [chemical binding]; other site
1123863007749	active site
1123863007750	substrate binding site [chemical binding]; other site
1123863007751	catalytic residue [active]
1123863007752	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863007753	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1123863007754	dimer interface [polypeptide binding]; other site
1123863007755	active site
1123863007756	metal binding site [ion binding]; metal-binding site
1123863007757	glutathione binding site [chemical binding]; other site
1123863007758	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1123863007759	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1123863007760	dimer interface [polypeptide binding]; other site
1123863007761	catalytic site [active]
1123863007762	putative active site [active]
1123863007763	putative substrate binding site [chemical binding]; other site
1123863007764	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1123863007765	putative GSH binding site [chemical binding]; other site
1123863007766	catalytic residues [active]
1123863007767	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1123863007768	NlpC/P60 family; Region: NLPC_P60; pfam00877
1123863007769	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1123863007770	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863007771	DNA binding site [nucleotide binding]
1123863007772	domain linker motif; other site
1123863007773	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1123863007774	dimerization interface [polypeptide binding]; other site
1123863007775	ligand binding site [chemical binding]; other site
1123863007776	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1123863007777	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863007778	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863007779	dimerization interface [polypeptide binding]; other site
1123863007780	putative transporter; Provisional; Region: PRK11043
1123863007781	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007782	putative substrate translocation pore; other site
1123863007783	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1123863007784	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863007785	S-adenosylmethionine binding site [chemical binding]; other site
1123863007786	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1123863007787	Lumazine binding domain; Region: Lum_binding; pfam00677
1123863007788	Lumazine binding domain; Region: Lum_binding; pfam00677
1123863007789	multidrug efflux protein; Reviewed; Region: PRK01766
1123863007790	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1123863007791	cation binding site [ion binding]; other site
1123863007792	pyruvate kinase; Provisional; Region: PRK09206
1123863007793	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1123863007794	domain interfaces; other site
1123863007795	active site
1123863007796	murein lipoprotein; Provisional; Region: PRK15396
1123863007797	L,D-transpeptidase; Provisional; Region: PRK10190
1123863007798	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1123863007799	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1123863007800	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1123863007801	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1123863007802	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1123863007803	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863007804	catalytic residue [active]
1123863007805	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1123863007806	FeS assembly protein SufD; Region: sufD; TIGR01981
1123863007807	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1123863007808	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1123863007809	Walker A/P-loop; other site
1123863007810	ATP binding site [chemical binding]; other site
1123863007811	Q-loop/lid; other site
1123863007812	ABC transporter signature motif; other site
1123863007813	Walker B; other site
1123863007814	D-loop; other site
1123863007815	H-loop/switch region; other site
1123863007816	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1123863007817	putative ABC transporter; Region: ycf24; CHL00085
1123863007818	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1123863007819	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1123863007820	FAD binding domain; Region: FAD_binding_4; pfam01565
1123863007821	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1123863007822	putative inner membrane protein; Provisional; Region: PRK10983
1123863007823	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1123863007824	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1123863007825	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1123863007826	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1123863007827	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1123863007828	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1123863007829	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1123863007830	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1123863007831	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1123863007832	hypothetical protein; Validated; Region: PRK00029
1123863007833	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1123863007834	NlpC/P60 family; Region: NLPC_P60; pfam00877
1123863007835	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1123863007836	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1123863007837	Walker A/P-loop; other site
1123863007838	ATP binding site [chemical binding]; other site
1123863007839	Q-loop/lid; other site
1123863007840	ABC transporter signature motif; other site
1123863007841	Walker B; other site
1123863007842	D-loop; other site
1123863007843	H-loop/switch region; other site
1123863007844	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1123863007845	catalytic residues [active]
1123863007846	dimer interface [polypeptide binding]; other site
1123863007847	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1123863007848	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863007849	ABC-ATPase subunit  interface; other site
1123863007850	dimer interface [polypeptide binding]; other site
1123863007851	putative PBP binding regions; other site
1123863007852	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1123863007853	IHF dimer interface [polypeptide binding]; other site
1123863007854	IHF - DNA interface [nucleotide binding]; other site
1123863007855	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1123863007856	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1123863007857	putative tRNA-binding site [nucleotide binding]; other site
1123863007858	B3/4 domain; Region: B3_4; pfam03483
1123863007859	tRNA synthetase B5 domain; Region: B5; smart00874
1123863007860	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1123863007861	dimer interface [polypeptide binding]; other site
1123863007862	motif 1; other site
1123863007863	motif 3; other site
1123863007864	motif 2; other site
1123863007865	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1123863007866	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1123863007867	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1123863007868	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1123863007869	dimer interface [polypeptide binding]; other site
1123863007870	motif 1; other site
1123863007871	active site
1123863007872	motif 2; other site
1123863007873	motif 3; other site
1123863007874	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1123863007875	23S rRNA binding site [nucleotide binding]; other site
1123863007876	L21 binding site [polypeptide binding]; other site
1123863007877	L13 binding site [polypeptide binding]; other site
1123863007878	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1123863007879	translation initiation factor IF-3; Region: infC; TIGR00168
1123863007880	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1123863007881	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1123863007882	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1123863007883	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1123863007884	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1123863007885	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1123863007886	active site
1123863007887	dimer interface [polypeptide binding]; other site
1123863007888	motif 1; other site
1123863007889	motif 2; other site
1123863007890	motif 3; other site
1123863007891	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1123863007892	anticodon binding site; other site
1123863007893	Protein of unknown function, DUF481; Region: DUF481; cl01213
1123863007894	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1123863007895	Fructosamine kinase; Region: Fructosamin_kin; pfam03881
1123863007896	Phosphotransferase enzyme family; Region: APH; pfam01636
1123863007897	YniB-like protein; Region: YniB; pfam14002
1123863007898	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1123863007899	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1123863007900	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863007901	motif II; other site
1123863007902	inner membrane protein; Provisional; Region: PRK11648
1123863007903	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1123863007904	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1123863007905	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1123863007906	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1123863007907	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863007908	putative substrate translocation pore; other site
1123863007909	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1123863007910	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1123863007911	homodimer interface [polypeptide binding]; other site
1123863007912	NAD binding pocket [chemical binding]; other site
1123863007913	ATP binding pocket [chemical binding]; other site
1123863007914	Mg binding site [ion binding]; other site
1123863007915	active-site loop [active]
1123863007916	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863007917	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863007918	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863007919	dimer interface [polypeptide binding]; other site
1123863007920	putative CheW interface [polypeptide binding]; other site
1123863007921	aromatic amino acid exporter; Provisional; Region: PRK11689
1123863007922	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1123863007923	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1123863007924	GIY-YIG motif/motif A; other site
1123863007925	active site
1123863007926	catalytic site [active]
1123863007927	putative DNA binding site [nucleotide binding]; other site
1123863007928	metal binding site [ion binding]; metal-binding site
1123863007929	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1123863007930	dimer interface [polypeptide binding]; other site
1123863007931	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1123863007932	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1123863007933	putative active site [active]
1123863007934	Zn binding site [ion binding]; other site
1123863007935	succinylarginine dihydrolase; Provisional; Region: PRK13281
1123863007936	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1123863007937	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1123863007938	NAD(P) binding site [chemical binding]; other site
1123863007939	catalytic residues [active]
1123863007940	arginine succinyltransferase; Provisional; Region: PRK10456
1123863007941	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1123863007942	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1123863007943	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863007944	inhibitor-cofactor binding pocket; inhibition site
1123863007945	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863007946	catalytic residue [active]
1123863007947	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1123863007948	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1123863007949	trimer interface [polypeptide binding]; other site
1123863007950	eyelet of channel; other site
1123863007951	putative invasin; Provisional; Region: PRK10177
1123863007952	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1123863007953	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1123863007954	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863007955	NAD(P) binding site [chemical binding]; other site
1123863007956	active site
1123863007957	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863007958	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863007959	TM-ABC transporter signature motif; other site
1123863007960	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863007961	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863007962	Walker A/P-loop; other site
1123863007963	ATP binding site [chemical binding]; other site
1123863007964	Q-loop/lid; other site
1123863007965	ABC transporter signature motif; other site
1123863007966	Walker B; other site
1123863007967	D-loop; other site
1123863007968	H-loop/switch region; other site
1123863007969	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863007970	Predicted periplasmic lipoprotein (DUF2291); Region: DUF2291; cl02395
1123863007971	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1123863007972	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1123863007973	short chain dehydrogenase; Provisional; Region: PRK06841
1123863007974	classical (c) SDRs; Region: SDR_c; cd05233
1123863007975	NAD(P) binding site [chemical binding]; other site
1123863007976	active site
1123863007977	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1123863007978	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1123863007979	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863007980	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1123863007981	active site
1123863007982	SAM binding site [chemical binding]; other site
1123863007983	homodimer interface [polypeptide binding]; other site
1123863007984	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1123863007985	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1123863007986	[4Fe-4S] binding site [ion binding]; other site
1123863007987	molybdopterin cofactor binding site; other site
1123863007988	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1123863007989	molybdopterin cofactor binding site; other site
1123863007990	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1123863007991	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1123863007992	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863007993	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1123863007994	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863007995	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1123863007996	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1123863007997	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1123863007998	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1123863007999	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1123863008000	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1123863008001	Walker A/P-loop; other site
1123863008002	ATP binding site [chemical binding]; other site
1123863008003	Q-loop/lid; other site
1123863008004	ABC transporter signature motif; other site
1123863008005	Walker B; other site
1123863008006	D-loop; other site
1123863008007	H-loop/switch region; other site
1123863008008	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1123863008009	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863008010	dimer interface [polypeptide binding]; other site
1123863008011	conserved gate region; other site
1123863008012	putative PBP binding loops; other site
1123863008013	ABC-ATPase subunit interface; other site
1123863008014	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1123863008015	NMT1-like family; Region: NMT1_2; pfam13379
1123863008016	Nitrate and nitrite sensing; Region: NIT; pfam08376
1123863008017	ANTAR domain; Region: ANTAR; pfam03861
1123863008018	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1123863008019	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1123863008020	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1123863008021	ligand binding site [chemical binding]; other site
1123863008022	ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331
1123863008023	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1123863008024	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; pfam09867
1123863008025	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1123863008026	type VI secretion system FHA domain protein; Region: VI_FHA; TIGR03354
1123863008027	phosphopeptide binding site; other site
1123863008028	Serine/threonine protein phosphatase [Signal transduction mechanisms]; Region: PTC1; COG0631
1123863008029	active site
1123863008030	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1123863008031	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1123863008032	active site
1123863008033	ATP binding site [chemical binding]; other site
1123863008034	substrate binding site [chemical binding]; other site
1123863008035	activation loop (A-loop); other site
1123863008036	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
1123863008037	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1123863008038	putative active site pocket [active]
1123863008039	dimerization interface [polypeptide binding]; other site
1123863008040	putative catalytic residue [active]
1123863008041	cation transport regulator; Reviewed; Region: chaB; PRK09582
1123863008042	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1123863008043	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1123863008044	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1123863008045	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1123863008046	hypothetical protein; Provisional; Region: PRK10941
1123863008047	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1123863008048	Invasion gene expression up-regulator, SirB; Region: SirB; pfam04247
1123863008049	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1123863008050	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863008051	S-adenosylmethionine binding site [chemical binding]; other site
1123863008052	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1123863008053	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1123863008054	RF-1 domain; Region: RF-1; pfam00472
1123863008055	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1123863008056	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1123863008057	tRNA; other site
1123863008058	putative tRNA binding site [nucleotide binding]; other site
1123863008059	putative NADP binding site [chemical binding]; other site
1123863008060	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1123863008061	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
1123863008062	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1123863008063	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1123863008064	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1123863008065	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1123863008066	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1123863008067	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1123863008068	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1123863008069	active site
1123863008070	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863008071	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863008072	metal binding site [ion binding]; metal-binding site
1123863008073	active site
1123863008074	I-site; other site
1123863008075	hypothetical protein; Provisional; Region: PRK10692
1123863008076	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1123863008077	putative active site [active]
1123863008078	catalytic residue [active]
1123863008079	GTP-binding protein YchF; Reviewed; Region: PRK09601
1123863008080	YchF GTPase; Region: YchF; cd01900
1123863008081	G1 box; other site
1123863008082	GTP/Mg2+ binding site [chemical binding]; other site
1123863008083	Switch I region; other site
1123863008084	G2 box; other site
1123863008085	Switch II region; other site
1123863008086	G3 box; other site
1123863008087	G4 box; other site
1123863008088	G5 box; other site
1123863008089	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1123863008090	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1123863008091	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1123863008092	Integrase core domain; Region: rve; pfam00665
1123863008093	Integrase core domain; Region: rve_3; pfam13683
1123863008094	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1123863008095	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1123863008096	tetramer interface [polypeptide binding]; other site
1123863008097	active site
1123863008098	Mg2+/Mn2+ binding site [ion binding]; other site
1123863008099	phosphonopyruvate decarboxylase; Region: Ppyr-DeCO2ase; TIGR03297
1123863008100	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1123863008101	PYR/PP interface [polypeptide binding]; other site
1123863008102	dimer interface [polypeptide binding]; other site
1123863008103	TPP binding site [chemical binding]; other site
1123863008104	Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as...; Region: TPP_PpyrDC; cd03371
1123863008105	TPP-binding site; other site
1123863008106	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
1123863008107	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1123863008108	Ligand Binding Site [chemical binding]; other site
1123863008109	Molecular Tunnel; other site
1123863008110	aspartate semialdehyde dehydrogenase; Region: PLN02383
1123863008111	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1123863008112	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1123863008113	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863008114	catalytic residue [active]
1123863008115	aspartate aminotransferase; Provisional; Region: PRK05764
1123863008116	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863008117	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863008118	homodimer interface [polypeptide binding]; other site
1123863008119	catalytic residue [active]
1123863008120	DDE superfamily endonuclease; Region: DDE_3; pfam13358
1123863008121	FOG: CBS domain [General function prediction only]; Region: COG0517
1123863008122	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1123863008123	Divalent cation transporter; Region: MgtE; pfam01769
1123863008124	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863008125	Coenzyme A binding pocket [chemical binding]; other site
1123863008126	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1123863008127	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1123863008128	active site
1123863008129	homotetramer interface [polypeptide binding]; other site
1123863008130	FIST N domain; Region: FIST; smart00897
1123863008131	FIST C domain; Region: FIST_C; pfam10442
1123863008132	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863008133	dimer interface [polypeptide binding]; other site
1123863008134	putative CheW interface [polypeptide binding]; other site
1123863008135	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1123863008136	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863008137	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1123863008138	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1123863008139	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1123863008140	Metal-binding active site; metal-binding site
1123863008141	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1123863008142	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008143	putative substrate translocation pore; other site
1123863008144	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008145	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1123863008146	major facilitator superfamily transporter; Provisional; Region: PRK05122
1123863008147	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008148	putative substrate translocation pore; other site
1123863008149	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1123863008150	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1123863008151	Flavoprotein; Region: Flavoprotein; pfam02441
1123863008152	MarR family; Region: MarR_2; cl17246
1123863008153	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1123863008154	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1123863008155	catalytic residues [active]
1123863008156	dimer interface [polypeptide binding]; other site
1123863008157	methionine synthase; Provisional; Region: PRK01207
1123863008158	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1123863008159	substrate binding site [chemical binding]; other site
1123863008160	THF binding site; other site
1123863008161	zinc-binding site [ion binding]; other site
1123863008162	Domain of unknown function (DUF1852); Region: DUF1852; pfam08908
1123863008163	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1123863008164	active site
1123863008165	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863008166	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1123863008167	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1123863008168	catalytic motif [active]
1123863008169	Zn binding site [ion binding]; other site
1123863008170	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
1123863008171	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1123863008172	Ectoine synthase; Region: Ectoine_synth; cl17598
1123863008173	Putative D-3-Phosphoglycerate Dehydrogenases; Region: PGDH_like_1; cd12169
1123863008174	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1123863008175	dimerization interface [polypeptide binding]; other site
1123863008176	NAD binding site [chemical binding]; other site
1123863008177	ligand binding site [chemical binding]; other site
1123863008178	catalytic site [active]
1123863008179	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1123863008180	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1123863008181	binding surface
1123863008182	TPR motif; other site
1123863008183	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1123863008184	RNA polymerase sigma factor; Provisional; Region: PRK12511
1123863008185	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1123863008186	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1123863008187	DNA binding residues [nucleotide binding]
1123863008188	YceI-like domain; Region: YceI; pfam04264
1123863008189	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863008190	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1123863008191	active site
1123863008192	metal binding site [ion binding]; metal-binding site
1123863008193	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
1123863008194	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1123863008195	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863008196	dimerization interface [polypeptide binding]; other site
1123863008197	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863008198	dimer interface [polypeptide binding]; other site
1123863008199	putative CheW interface [polypeptide binding]; other site
1123863008200	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1123863008201	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863008202	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1123863008203	Amidase; Region: Amidase; pfam01425
1123863008204	Dehydratase family; Region: ILVD_EDD; cl00340
1123863008205	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1123863008206	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863008207	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1123863008208	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863008209	N-terminal plug; other site
1123863008210	ligand-binding site [chemical binding]; other site
1123863008211	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1123863008212	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1123863008213	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1123863008214	inhibitor site; inhibition site
1123863008215	active site
1123863008216	dimer interface [polypeptide binding]; other site
1123863008217	catalytic residue [active]
1123863008218	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1123863008219	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
1123863008220	conserved cys residue [active]
1123863008221	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
1123863008222	Amidohydrolase; Region: Amidohydro_2; pfam04909
1123863008223	benzoate transport; Region: 2A0115; TIGR00895
1123863008224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008225	putative substrate translocation pore; other site
1123863008226	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1123863008227	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863008228	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863008229	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863008230	dimerization interface [polypeptide binding]; other site
1123863008231	putative DNA binding site [nucleotide binding]; other site
1123863008232	putative Zn2+ binding site [ion binding]; other site
1123863008233	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1123863008234	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1123863008235	FMN binding site [chemical binding]; other site
1123863008236	active site
1123863008237	substrate binding site [chemical binding]; other site
1123863008238	catalytic residue [active]
1123863008239	Uncharacterized protein conserved in bacteria (DUF2309); Region: DUF2309; pfam10070
1123863008240	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3002
1123863008241	NADH dehydrogenase subunit L; Provisional; Region: PRK08168
1123863008242	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1123863008243	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1123863008244	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863008245	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863008246	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1123863008247	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1123863008248	The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain; Region: ASCH; smart01022
1123863008249	bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404
1123863008250	Cupin; Region: Cupin_1; smart00835
1123863008251	Cupin; Region: Cupin_1; smart00835
1123863008252	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II and Staphylococcus aureus AldA1 (SACOL0154)-like; Region: ALDH_ACDHII_AcoD-like; cd07559
1123863008253	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1123863008254	NAD(P) binding site [chemical binding]; other site
1123863008255	catalytic residues [active]
1123863008256	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863008257	S-adenosylmethionine binding site [chemical binding]; other site
1123863008258	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1123863008259	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1123863008260	catalytic triad [active]
1123863008261	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1123863008262	EamA-like transporter family; Region: EamA; pfam00892
1123863008263	EamA-like transporter family; Region: EamA; pfam00892
1123863008264	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
1123863008265	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1123863008266	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1123863008267	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1123863008268	putative hydrolase; Validated; Region: PRK09248
1123863008269	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1123863008270	active site
1123863008271	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1123863008272	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1123863008273	putative ligand binding site [chemical binding]; other site
1123863008274	NAD binding site [chemical binding]; other site
1123863008275	dimerization interface [polypeptide binding]; other site
1123863008276	catalytic site [active]
1123863008277	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1123863008278	Trehalase; Region: Trehalase; cl17346
1123863008279	hypothetical protein; Provisional; Region: PRK10457
1123863008280	Flagellar regulator YcgR; Region: YcgR; pfam07317
1123863008281	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1123863008282	PilZ domain; Region: PilZ; pfam07238
1123863008283	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1123863008284	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1123863008285	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
1123863008286	bacterial glycerol kinase 2-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_GK2_bacteria; cd07791
1123863008287	N- and C-terminal domain interface [polypeptide binding]; other site
1123863008288	active site
1123863008289	MgATP binding site [chemical binding]; other site
1123863008290	catalytic site [active]
1123863008291	metal binding site [ion binding]; metal-binding site
1123863008292	putative homotetramer interface [polypeptide binding]; other site
1123863008293	putative homodimer interface [polypeptide binding]; other site
1123863008294	glycerol binding site [chemical binding]; other site
1123863008295	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1123863008296	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1123863008297	PYR/PP interface [polypeptide binding]; other site
1123863008298	dimer interface [polypeptide binding]; other site
1123863008299	TPP binding site [chemical binding]; other site
1123863008300	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1123863008301	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
1123863008302	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1123863008303	TPP-binding site [chemical binding]; other site
1123863008304	dimer interface [polypeptide binding]; other site
1123863008305	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1123863008306	MarR family; Region: MarR_2; cl17246
1123863008307	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1123863008308	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1123863008309	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1123863008310	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1123863008311	catalytic residue [active]
1123863008312	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1123863008313	dimer interface [polypeptide binding]; other site
1123863008314	catalytic triad [active]
1123863008315	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1123863008316	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863008317	Coenzyme A binding pocket [chemical binding]; other site
1123863008318	CsbD-like; Region: CsbD; pfam05532
1123863008319	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008320	metabolite-proton symporter; Region: 2A0106; TIGR00883
1123863008321	putative substrate translocation pore; other site
1123863008322	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1123863008323	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863008324	DNA-binding site [nucleotide binding]; DNA binding site
1123863008325	UTRA domain; Region: UTRA; pfam07702
1123863008326	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863008327	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1123863008328	substrate binding site [chemical binding]; other site
1123863008329	ATP binding site [chemical binding]; other site
1123863008330	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1123863008331	nucleoside transporter; Region: 2A0110; TIGR00889
1123863008332	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008333	putative substrate translocation pore; other site
1123863008334	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1123863008335	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863008336	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863008337	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1123863008338	Protein export membrane protein; Region: SecD_SecF; cl14618
1123863008339	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1123863008340	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1123863008341	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863008342	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1123863008343	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863008344	hypothetical protein; Provisional; Region: PRK06185
1123863008345	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1123863008346	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1123863008347	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
1123863008348	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863008349	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1123863008350	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
1123863008351	PapC N-terminal domain; Region: PapC_N; pfam13954
1123863008352	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1123863008353	PapC C-terminal domain; Region: PapC_C; pfam13953
1123863008354	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
1123863008355	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
1123863008356	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863008357	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1123863008358	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1123863008359	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1123863008360	putative active site [active]
1123863008361	isocitrate dehydrogenase; Validated; Region: PRK07362
1123863008362	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1123863008363	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1123863008364	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1123863008365	active site
1123863008366	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1123863008367	nudix motif; other site
1123863008368	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1123863008369	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1123863008370	putative lysogenization regulator; Reviewed; Region: PRK00218
1123863008371	adenylosuccinate lyase; Provisional; Region: PRK09285
1123863008372	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1123863008373	tetramer interface [polypeptide binding]; other site
1123863008374	active site
1123863008375	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1123863008376	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863008377	active site
1123863008378	phosphorylation site [posttranslational modification]
1123863008379	intermolecular recognition site; other site
1123863008380	dimerization interface [polypeptide binding]; other site
1123863008381	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863008382	DNA binding site [nucleotide binding]
1123863008383	sensor protein PhoQ; Provisional; Region: PRK10815
1123863008384	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1123863008385	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863008386	dimer interface [polypeptide binding]; other site
1123863008387	phosphorylation site [posttranslational modification]
1123863008388	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863008389	ATP binding site [chemical binding]; other site
1123863008390	Mg2+ binding site [ion binding]; other site
1123863008391	G-X-G motif; other site
1123863008392	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1123863008393	Cupin-like domain; Region: Cupin_8; pfam13621
1123863008394	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1123863008395	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1123863008396	metal binding site [ion binding]; metal-binding site
1123863008397	dimer interface [polypeptide binding]; other site
1123863008398	NAD-dependent deacetylase; Provisional; Region: PRK00481
1123863008399	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1123863008400	NAD+ binding site [chemical binding]; other site
1123863008401	substrate binding site [chemical binding]; other site
1123863008402	Zn binding site [ion binding]; other site
1123863008403	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1123863008404	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1123863008405	FtsX-like permease family; Region: FtsX; pfam02687
1123863008406	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1123863008407	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1123863008408	Walker A/P-loop; other site
1123863008409	ATP binding site [chemical binding]; other site
1123863008410	Q-loop/lid; other site
1123863008411	ABC transporter signature motif; other site
1123863008412	Walker B; other site
1123863008413	D-loop; other site
1123863008414	H-loop/switch region; other site
1123863008415	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1123863008416	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1123863008417	FtsX-like permease family; Region: FtsX; pfam02687
1123863008418	transcription-repair coupling factor; Provisional; Region: PRK10689
1123863008419	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1123863008420	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863008421	ATP binding site [chemical binding]; other site
1123863008422	putative Mg++ binding site [ion binding]; other site
1123863008423	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863008424	nucleotide binding region [chemical binding]; other site
1123863008425	ATP-binding site [chemical binding]; other site
1123863008426	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1123863008427	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1123863008428	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1123863008429	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1123863008430	MarR family; Region: MarR_2; pfam12802
1123863008431	hypothetical protein; Provisional; Region: PRK11280
1123863008432	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1123863008433	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863008434	hypothetical protein; Provisional; Region: PRK04940
1123863008435	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1123863008436	beta-hexosaminidase; Provisional; Region: PRK05337
1123863008437	thiamine kinase; Region: ycfN_thiK; TIGR02721
1123863008438	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1123863008439	substrate binding site [chemical binding]; other site
1123863008440	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1123863008441	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1123863008442	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1123863008443	putative dimer interface [polypeptide binding]; other site
1123863008444	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1123863008445	nucleotide binding site/active site [active]
1123863008446	HIT family signature motif; other site
1123863008447	catalytic residue [active]
1123863008448	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863008449	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863008450	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863008451	dimer interface [polypeptide binding]; other site
1123863008452	putative CheW interface [polypeptide binding]; other site
1123863008453	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1123863008454	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1123863008455	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1123863008456	active site turn [active]
1123863008457	phosphorylation site [posttranslational modification]
1123863008458	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1123863008459	active site
1123863008460	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1123863008461	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1123863008462	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1123863008463	thymidylate kinase; Validated; Region: tmk; PRK00698
1123863008464	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1123863008465	TMP-binding site; other site
1123863008466	ATP-binding site [chemical binding]; other site
1123863008467	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1123863008468	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1123863008469	dimerization interface [polypeptide binding]; other site
1123863008470	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1123863008471	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1123863008472	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863008473	catalytic residue [active]
1123863008474	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1123863008475	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1123863008476	dimer interface [polypeptide binding]; other site
1123863008477	active site
1123863008478	acyl carrier protein; Provisional; Region: acpP; PRK00982
1123863008479	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1123863008480	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1123863008481	NAD(P) binding site [chemical binding]; other site
1123863008482	homotetramer interface [polypeptide binding]; other site
1123863008483	homodimer interface [polypeptide binding]; other site
1123863008484	active site
1123863008485	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1123863008486	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1123863008487	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1123863008488	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1123863008489	dimer interface [polypeptide binding]; other site
1123863008490	active site
1123863008491	CoA binding pocket [chemical binding]; other site
1123863008492	putative phosphate acyltransferase; Provisional; Region: PRK05331
1123863008493	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1123863008494	hypothetical protein; Provisional; Region: PRK11193
1123863008495	Maf-like protein; Region: Maf; pfam02545
1123863008496	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1123863008497	active site
1123863008498	dimer interface [polypeptide binding]; other site
1123863008499	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1123863008500	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1123863008501	RNA binding surface [nucleotide binding]; other site
1123863008502	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1123863008503	active site
1123863008504	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
1123863008505	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1123863008506	homodimer interface [polypeptide binding]; other site
1123863008507	oligonucleotide binding site [chemical binding]; other site
1123863008508	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1123863008509	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1123863008510	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1123863008511	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1123863008512	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1123863008513	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1123863008514	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1123863008515	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1123863008516	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1123863008517	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1123863008518	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1123863008519	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1123863008520	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1123863008521	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1123863008522	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1123863008523	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
1123863008524	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1123863008525	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1123863008526	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1123863008527	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1123863008528	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1123863008529	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1123863008530	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1123863008531	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1123863008532	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1123863008533	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1123863008534	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1123863008535	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1123863008536	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1123863008537	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1123863008538	SAF-like; Region: SAF_2; pfam13144
1123863008539	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1123863008540	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
1123863008541	FlgN protein; Region: FlgN; cl09176
1123863008542	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
1123863008543	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863008544	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863008545	dimer interface [polypeptide binding]; other site
1123863008546	putative CheW interface [polypeptide binding]; other site
1123863008547	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1123863008548	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1123863008549	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1123863008550	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863008551	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1123863008552	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1123863008553	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1123863008554	lipoprotein; Provisional; Region: PRK10598
1123863008555	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1123863008556	active site
1123863008557	substrate binding pocket [chemical binding]; other site
1123863008558	dimer interface [polypeptide binding]; other site
1123863008559	DNA damage-inducible protein I; Provisional; Region: PRK10597
1123863008560	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1123863008561	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1123863008562	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863008563	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1123863008564	hypothetical protein; Provisional; Region: PRK03757
1123863008565	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1123863008566	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1123863008567	active site residue [active]
1123863008568	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1123863008569	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1123863008570	putative acyl-acceptor binding pocket; other site
1123863008571	TetR family transcriptional regulator; Provisional; Region: PRK14996
1123863008572	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863008573	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1123863008574	hypothetical protein; Provisional; Region: PRK09272
1123863008575	secY/secA suppressor protein; Provisional; Region: PRK11467
1123863008576	lipoprotein; Provisional; Region: PRK10175
1123863008577	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1123863008578	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1123863008579	Ligand binding site; other site
1123863008580	DXD motif; other site
1123863008581	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1123863008582	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; cl15433
1123863008583	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1123863008584	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1123863008585	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1123863008586	PLD-like domain; Region: PLDc_2; pfam13091
1123863008587	putative active site [active]
1123863008588	catalytic site [active]
1123863008589	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1123863008590	PLD-like domain; Region: PLDc_2; pfam13091
1123863008591	putative active site [active]
1123863008592	catalytic site [active]
1123863008593	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1123863008594	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1123863008595	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863008596	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863008597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008598	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1123863008599	putative substrate translocation pore; other site
1123863008600	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1123863008601	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1123863008602	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1123863008603	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1123863008604	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863008605	Protein of unknown function (DUF2000); Region: DUF2000; cl02074
1123863008606	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1123863008607	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1123863008608	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1123863008609	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1123863008610	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1123863008611	Transposase; Region: HTH_Tnp_1; cl17663
1123863008612	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1123863008613	SEC-C motif; Region: SEC-C; pfam02810
1123863008614	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1123863008615	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1123863008616	active site
1123863008617	DNA binding site [nucleotide binding]
1123863008618	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1123863008619	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1123863008620	Phage-related protein, tail component [Function unknown]; Region: COG4733
1123863008621	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1123863008622	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1123863008623	Interdomain contacts; other site
1123863008624	Cytokine receptor motif; other site
1123863008625	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1123863008626	Phage-related protein, tail component [Function unknown]; Region: COG4723
1123863008627	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1123863008628	MPN+ (JAMM) motif; other site
1123863008629	Zinc-binding site [ion binding]; other site
1123863008630	NlpC/P60 family; Region: NLPC_P60; pfam00877
1123863008631	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1123863008632	Phage minor tail protein L; Region: Phage_tail_L; cl01908
1123863008633	Phage minor tail protein; Region: Phage_min_tail; cl01940
1123863008634	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1123863008635	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
1123863008636	Phage-related minor tail protein [Function unknown]; Region: COG5281
1123863008637	Bacteriophage protein of unknown function (DUF646); Region: DUF646; pfam04883
1123863008638	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
1123863008639	oligomerization interface [polypeptide binding]; other site
1123863008640	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1123863008641	Phage capsid family; Region: Phage_capsid; pfam05065
1123863008642	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1123863008643	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1123863008644	oligomer interface [polypeptide binding]; other site
1123863008645	active site residues [active]
1123863008646	Phage portal protein; Region: Phage_portal; pfam04860
1123863008647	Phage-related protein [Function unknown]; Region: COG4695
1123863008648	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
1123863008649	Phage terminase, small subunit; Region: Terminase_4; cl01525
1123863008650	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1123863008651	catalytic residues [active]
1123863008652	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1123863008653	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1123863008654	potential protein location (hypothetical protein) that overlaps protein (phage protein)
1123863008655	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1123863008656	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
1123863008657	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
1123863008658	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1123863008659	active site
1123863008660	NTP binding site [chemical binding]; other site
1123863008661	nucleic acid binding site [nucleotide binding]; other site
1123863008662	ParB-like nuclease domain; Region: ParB; smart00470
1123863008663	KorB domain; Region: KorB; pfam08535
1123863008664	Conserved phage C-terminus (Phg_2220_C); Region: Phg_2220_C; pfam09524
1123863008665	Protein of unknown function (DUF1317); Region: DUF1317; pfam07026
1123863008666	TIGR02646 family protein; Region: TIGR02646
1123863008667	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1123863008668	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1123863008669	active site
1123863008670	DNA binding site [nucleotide binding]
1123863008671	Int/Topo IB signature motif; other site
1123863008672	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1123863008673	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1123863008674	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1123863008675	active site
1123863008676	catalytic site [active]
1123863008677	putative DNA binding site [nucleotide binding]; other site
1123863008678	GIY-YIG motif/motif A; other site
1123863008679	metal binding site [ion binding]; metal-binding site
1123863008680	UvrB/uvrC motif; Region: UVR; pfam02151
1123863008681	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1123863008682	response regulator; Provisional; Region: PRK09483
1123863008683	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863008684	active site
1123863008685	phosphorylation site [posttranslational modification]
1123863008686	intermolecular recognition site; other site
1123863008687	dimerization interface [polypeptide binding]; other site
1123863008688	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1123863008689	DNA binding residues [nucleotide binding]
1123863008690	dimerization interface [polypeptide binding]; other site
1123863008691	hypothetical protein; Provisional; Region: PRK10613
1123863008692	Autoinducer synthetase; Region: Autoind_synth; cl17404
1123863008693	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1123863008694	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1123863008695	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1123863008696	DNA binding residues [nucleotide binding]
1123863008697	dimerization interface [polypeptide binding]; other site
1123863008698	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1123863008699	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1123863008700	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
1123863008701	pyrimidine utilization regulatory protein R; Region: RutR; TIGR03613
1123863008702	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863008703	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1123863008704	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1123863008705	EamA-like transporter family; Region: EamA; pfam00892
1123863008706	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1123863008707	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1123863008708	hypothetical protein; Provisional; Region: PRK10174
1123863008709	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1123863008710	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1123863008711	NAD(P) binding site [chemical binding]; other site
1123863008712	catalytic residues [active]
1123863008713	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1123863008714	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1123863008715	catalytic core [active]
1123863008716	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1123863008717	YccA-like proteins; Region: YccA_like; cd10433
1123863008718	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1123863008719	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1123863008720	sulfur relay protein, TusE/DsrC/DsvC family; Region: dsrC_tusE_dsvC; TIGR03342
1123863008721	acylphosphatase; Provisional; Region: PRK14426
1123863008722	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1123863008723	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1123863008724	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1123863008725	putative RNA binding site [nucleotide binding]; other site
1123863008726	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863008727	S-adenosylmethionine binding site [chemical binding]; other site
1123863008728	heat shock protein HspQ; Provisional; Region: PRK14129
1123863008729	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1123863008730	hypothetical protein; Provisional; Region: PRK03641
1123863008731	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
1123863008732	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1123863008733	active site
1123863008734	dimer interfaces [polypeptide binding]; other site
1123863008735	catalytic residues [active]
1123863008736	DNA helicase IV; Provisional; Region: helD; PRK11054
1123863008737	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1123863008738	Part of AAA domain; Region: AAA_19; pfam13245
1123863008739	Family description; Region: UvrD_C_2; pfam13538
1123863008740	Predicted membrane protein [Function unknown]; Region: COG3304
1123863008741	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1123863008742	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1123863008743	TIGR01666 family membrane protein; Region: YCCS
1123863008744	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1123863008745	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1123863008746	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1123863008747	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1123863008748	SOS cell division inhibitor; Provisional; Region: PRK10595
1123863008749	outer membrane protein A; Reviewed; Region: PRK10808
1123863008750	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1123863008751	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1123863008752	ligand binding site [chemical binding]; other site
1123863008753	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1123863008754	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1123863008755	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1123863008756	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1123863008757	active site 1 [active]
1123863008758	dimer interface [polypeptide binding]; other site
1123863008759	active site 2 [active]
1123863008760	Ribosome modulation factor; Region: RMF; pfam04957
1123863008761	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1123863008762	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1123863008763	paraquat-inducible protein B; Provisional; Region: PRK10807
1123863008764	mce related protein; Region: MCE; pfam02470
1123863008765	mce related protein; Region: MCE; pfam02470
1123863008766	mce related protein; Region: MCE; pfam02470
1123863008767	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1123863008768	Paraquat-inducible protein A; Region: PqiA; pfam04403
1123863008769	Paraquat-inducible protein A; Region: PqiA; pfam04403
1123863008770	ABC transporter ATPase component; Reviewed; Region: PRK11147
1123863008771	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863008772	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863008773	Walker A/P-loop; other site
1123863008774	ATP binding site [chemical binding]; other site
1123863008775	Q-loop/lid; other site
1123863008776	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863008777	ABC transporter signature motif; other site
1123863008778	Walker B; other site
1123863008779	D-loop; other site
1123863008780	ABC transporter; Region: ABC_tran_2; pfam12848
1123863008781	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863008782	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1123863008783	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1123863008784	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1123863008785	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863008786	S-adenosylmethionine binding site [chemical binding]; other site
1123863008787	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1123863008788	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1123863008789	MOSC domain; Region: MOSC; pfam03473
1123863008790	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1123863008791	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1123863008792	catalytic loop [active]
1123863008793	iron binding site [ion binding]; other site
1123863008794	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1123863008795	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1123863008796	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1123863008797	quinone interaction residues [chemical binding]; other site
1123863008798	active site
1123863008799	catalytic residues [active]
1123863008800	FMN binding site [chemical binding]; other site
1123863008801	substrate binding site [chemical binding]; other site
1123863008802	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1123863008803	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1123863008804	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1123863008805	active site
1123863008806	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
1123863008807	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1123863008808	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1123863008809	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863008810	substrate binding pocket [chemical binding]; other site
1123863008811	membrane-bound complex binding site; other site
1123863008812	hinge residues; other site
1123863008813	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1123863008814	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1123863008815	active site
1123863008816	dimer interface [polypeptide binding]; other site
1123863008817	non-prolyl cis peptide bond; other site
1123863008818	insertion regions; other site
1123863008819	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1123863008820	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863008821	dimer interface [polypeptide binding]; other site
1123863008822	conserved gate region; other site
1123863008823	putative PBP binding loops; other site
1123863008824	ABC-ATPase subunit interface; other site
1123863008825	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
1123863008826	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1123863008827	Walker A/P-loop; other site
1123863008828	ATP binding site [chemical binding]; other site
1123863008829	Q-loop/lid; other site
1123863008830	ABC transporter signature motif; other site
1123863008831	Walker B; other site
1123863008832	D-loop; other site
1123863008833	H-loop/switch region; other site
1123863008834	aminopeptidase N; Provisional; Region: pepN; PRK14015
1123863008835	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1123863008836	active site
1123863008837	Zn binding site [ion binding]; other site
1123863008838	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1123863008839	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1123863008840	active site
1123863008841	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1123863008842	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1123863008843	putative dimer interface [polypeptide binding]; other site
1123863008844	putative anticodon binding site; other site
1123863008845	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1123863008846	homodimer interface [polypeptide binding]; other site
1123863008847	motif 1; other site
1123863008848	motif 2; other site
1123863008849	active site
1123863008850	motif 3; other site
1123863008851	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1123863008852	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1123863008853	trimer interface [polypeptide binding]; other site
1123863008854	eyelet of channel; other site
1123863008855	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1123863008856	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863008857	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863008858	homodimer interface [polypeptide binding]; other site
1123863008859	catalytic residue [active]
1123863008860	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1123863008861	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1123863008862	Peptidase M15; Region: Peptidase_M15_3; cl01194
1123863008863	murein L,D-transpeptidase; Provisional; Region: PRK10594
1123863008864	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1123863008865	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1123863008866	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1123863008867	cell division protein MukB; Provisional; Region: mukB; PRK04863
1123863008868	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1123863008869	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1123863008870	condesin subunit E; Provisional; Region: PRK05256
1123863008871	condesin subunit F; Provisional; Region: PRK05260
1123863008872	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1123863008873	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863008874	S-adenosylmethionine binding site [chemical binding]; other site
1123863008875	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1123863008876	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1123863008877	putative active site [active]
1123863008878	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1123863008879	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1123863008880	Ligand binding site; other site
1123863008881	oligomer interface; other site
1123863008882	Trm112p-like protein; Region: Trm112p; cl01066
1123863008883	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1123863008884	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1123863008885	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1123863008886	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1123863008887	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1123863008888	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1123863008889	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1123863008890	Walker A/P-loop; other site
1123863008891	ATP binding site [chemical binding]; other site
1123863008892	Q-loop/lid; other site
1123863008893	ABC transporter signature motif; other site
1123863008894	Walker B; other site
1123863008895	D-loop; other site
1123863008896	H-loop/switch region; other site
1123863008897	ComEC family competence protein; Provisional; Region: PRK11539
1123863008898	Competence protein; Region: Competence; pfam03772
1123863008899	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1123863008900	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1123863008901	IHF dimer interface [polypeptide binding]; other site
1123863008902	IHF - DNA interface [nucleotide binding]; other site
1123863008903	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1123863008904	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1123863008905	RNA binding site [nucleotide binding]; other site
1123863008906	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1123863008907	RNA binding site [nucleotide binding]; other site
1123863008908	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1123863008909	RNA binding site [nucleotide binding]; other site
1123863008910	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1123863008911	RNA binding site [nucleotide binding]; other site
1123863008912	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1123863008913	RNA binding site [nucleotide binding]; other site
1123863008914	cytidylate kinase; Provisional; Region: cmk; PRK00023
1123863008915	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1123863008916	CMP-binding site; other site
1123863008917	The sites determining sugar specificity; other site
1123863008918	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1123863008919	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1123863008920	hinge; other site
1123863008921	active site
1123863008922	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1123863008923	homodimer interface [polypeptide binding]; other site
1123863008924	substrate-cofactor binding pocket; other site
1123863008925	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863008926	catalytic residue [active]
1123863008927	uncharacterized domain; Region: TIGR00702
1123863008928	YcaO-like family; Region: YcaO; pfam02624
1123863008929	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1123863008930	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1123863008931	Pyruvate formate lyase 1; Region: PFL1; cd01678
1123863008932	coenzyme A binding site [chemical binding]; other site
1123863008933	active site
1123863008934	catalytic residues [active]
1123863008935	glycine loop; other site
1123863008936	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1123863008937	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863008938	FeS/SAM binding site; other site
1123863008939	putative MFS family transporter protein; Provisional; Region: PRK03633
1123863008940	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008941	putative substrate translocation pore; other site
1123863008942	seryl-tRNA synthetase; Provisional; Region: PRK05431
1123863008943	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1123863008944	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1123863008945	dimer interface [polypeptide binding]; other site
1123863008946	active site
1123863008947	motif 1; other site
1123863008948	motif 2; other site
1123863008949	motif 3; other site
1123863008950	recombination factor protein RarA; Reviewed; Region: PRK13342
1123863008951	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863008952	Walker A motif; other site
1123863008953	ATP binding site [chemical binding]; other site
1123863008954	Walker B motif; other site
1123863008955	arginine finger; other site
1123863008956	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1123863008957	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1123863008958	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1123863008959	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863008960	DNA translocase FtsK; Provisional; Region: PRK10263
1123863008961	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1123863008962	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1123863008963	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1123863008964	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863008965	putative DNA binding site [nucleotide binding]; other site
1123863008966	putative Zn2+ binding site [ion binding]; other site
1123863008967	AsnC family; Region: AsnC_trans_reg; pfam01037
1123863008968	thioredoxin reductase; Provisional; Region: PRK10262
1123863008969	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863008970	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863008971	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1123863008972	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1123863008973	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1123863008974	Walker A/P-loop; other site
1123863008975	ATP binding site [chemical binding]; other site
1123863008976	Q-loop/lid; other site
1123863008977	ABC transporter signature motif; other site
1123863008978	Walker B; other site
1123863008979	D-loop; other site
1123863008980	H-loop/switch region; other site
1123863008981	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1123863008982	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863008983	Walker A/P-loop; other site
1123863008984	ATP binding site [chemical binding]; other site
1123863008985	Q-loop/lid; other site
1123863008986	ABC transporter signature motif; other site
1123863008987	Walker B; other site
1123863008988	D-loop; other site
1123863008989	H-loop/switch region; other site
1123863008990	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1123863008991	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1123863008992	rRNA binding site [nucleotide binding]; other site
1123863008993	predicted 30S ribosome binding site; other site
1123863008994	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1123863008995	Clp amino terminal domain; Region: Clp_N; pfam02861
1123863008996	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863008997	Walker A motif; other site
1123863008998	ATP binding site [chemical binding]; other site
1123863008999	Walker B motif; other site
1123863009000	arginine finger; other site
1123863009001	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863009002	Walker A motif; other site
1123863009003	ATP binding site [chemical binding]; other site
1123863009004	Walker B motif; other site
1123863009005	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1123863009006	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1123863009007	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1123863009008	DNA-binding site [nucleotide binding]; DNA binding site
1123863009009	RNA-binding motif; other site
1123863009010	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1123863009011	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1123863009012	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1123863009013	putative active site [active]
1123863009014	putative metal-binding site [ion binding]; other site
1123863009015	Predicted membrane protein [Function unknown]; Region: COG2431
1123863009016	pyruvate dehydrogenase; Provisional; Region: PRK09124
1123863009017	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1123863009018	PYR/PP interface [polypeptide binding]; other site
1123863009019	dimer interface [polypeptide binding]; other site
1123863009020	tetramer interface [polypeptide binding]; other site
1123863009021	TPP binding site [chemical binding]; other site
1123863009022	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1123863009023	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1123863009024	TPP-binding site [chemical binding]; other site
1123863009025	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1123863009026	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1123863009027	tetramer interface [polypeptide binding]; other site
1123863009028	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863009029	catalytic residue [active]
1123863009030	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1123863009031	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1123863009032	amidase catalytic site [active]
1123863009033	Zn binding residues [ion binding]; other site
1123863009034	substrate binding site [chemical binding]; other site
1123863009035	hypothetical protein; Provisional; Region: PRK02877
1123863009036	putative lipoprotein; Provisional; Region: PRK10533
1123863009037	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1123863009038	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863009039	Walker A/P-loop; other site
1123863009040	ATP binding site [chemical binding]; other site
1123863009041	Q-loop/lid; other site
1123863009042	ABC transporter signature motif; other site
1123863009043	Walker B; other site
1123863009044	D-loop; other site
1123863009045	H-loop/switch region; other site
1123863009046	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1123863009047	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863009048	substrate binding pocket [chemical binding]; other site
1123863009049	membrane-bound complex binding site; other site
1123863009050	hinge residues; other site
1123863009051	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863009052	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009053	dimer interface [polypeptide binding]; other site
1123863009054	conserved gate region; other site
1123863009055	putative PBP binding loops; other site
1123863009056	ABC-ATPase subunit interface; other site
1123863009057	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009058	dimer interface [polypeptide binding]; other site
1123863009059	conserved gate region; other site
1123863009060	putative PBP binding loops; other site
1123863009061	ABC-ATPase subunit interface; other site
1123863009062	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1123863009063	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863009064	substrate binding pocket [chemical binding]; other site
1123863009065	membrane-bound complex binding site; other site
1123863009066	hinge residues; other site
1123863009067	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1123863009068	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863009069	S-adenosylmethionine binding site [chemical binding]; other site
1123863009070	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1123863009071	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1123863009072	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009073	dimer interface [polypeptide binding]; other site
1123863009074	conserved gate region; other site
1123863009075	putative PBP binding loops; other site
1123863009076	ABC-ATPase subunit interface; other site
1123863009077	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009078	dimer interface [polypeptide binding]; other site
1123863009079	conserved gate region; other site
1123863009080	putative PBP binding loops; other site
1123863009081	ABC-ATPase subunit interface; other site
1123863009082	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1123863009083	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863009084	Walker A/P-loop; other site
1123863009085	ATP binding site [chemical binding]; other site
1123863009086	Q-loop/lid; other site
1123863009087	ABC transporter signature motif; other site
1123863009088	Walker B; other site
1123863009089	D-loop; other site
1123863009090	H-loop/switch region; other site
1123863009091	TOBE domain; Region: TOBE_2; pfam08402
1123863009092	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1123863009093	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1123863009094	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1123863009095	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1123863009096	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1123863009097	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1123863009098	dimer interface [polypeptide binding]; other site
1123863009099	FMN binding site [chemical binding]; other site
1123863009100	NADPH bind site [chemical binding]; other site
1123863009101	Protein of unknown function (DUF1418); Region: DUF1418; cl11648
1123863009102	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1123863009103	GSH binding site [chemical binding]; other site
1123863009104	catalytic residues [active]
1123863009105	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1123863009106	putative transporter; Provisional; Region: PRK04972
1123863009107	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1123863009108	TrkA-C domain; Region: TrkA_C; pfam02080
1123863009109	TrkA-C domain; Region: TrkA_C; pfam02080
1123863009110	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1123863009111	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1123863009112	active site
1123863009113	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1123863009114	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1123863009115	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1123863009116	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1123863009117	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1123863009118	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1123863009119	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1123863009120	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1123863009121	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1123863009122	active site clefts [active]
1123863009123	zinc binding site [ion binding]; other site
1123863009124	dimer interface [polypeptide binding]; other site
1123863009125	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1123863009126	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1123863009127	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863009128	FeS/SAM binding site; other site
1123863009129	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1123863009130	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1123863009131	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1123863009132	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009133	dimer interface [polypeptide binding]; other site
1123863009134	conserved gate region; other site
1123863009135	putative PBP binding loops; other site
1123863009136	ABC-ATPase subunit interface; other site
1123863009137	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1123863009138	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009139	dimer interface [polypeptide binding]; other site
1123863009140	conserved gate region; other site
1123863009141	putative PBP binding loops; other site
1123863009142	ABC-ATPase subunit interface; other site
1123863009143	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1123863009144	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1123863009145	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1123863009146	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863009147	Walker A/P-loop; other site
1123863009148	ATP binding site [chemical binding]; other site
1123863009149	Q-loop/lid; other site
1123863009150	ABC transporter signature motif; other site
1123863009151	Walker B; other site
1123863009152	D-loop; other site
1123863009153	H-loop/switch region; other site
1123863009154	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1123863009155	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863009156	Walker A/P-loop; other site
1123863009157	ATP binding site [chemical binding]; other site
1123863009158	Q-loop/lid; other site
1123863009159	ABC transporter signature motif; other site
1123863009160	Walker B; other site
1123863009161	D-loop; other site
1123863009162	H-loop/switch region; other site
1123863009163	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1123863009164	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1123863009165	catalytic nucleophile [active]
1123863009166	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1123863009167	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1123863009168	dimer interface [polypeptide binding]; other site
1123863009169	putative functional site; other site
1123863009170	putative MPT binding site; other site
1123863009171	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1123863009172	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1123863009173	ATP binding site [chemical binding]; other site
1123863009174	substrate interface [chemical binding]; other site
1123863009175	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1123863009176	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863009177	Walker A/P-loop; other site
1123863009178	ATP binding site [chemical binding]; other site
1123863009179	Q-loop/lid; other site
1123863009180	ABC transporter signature motif; other site
1123863009181	Walker B; other site
1123863009182	D-loop; other site
1123863009183	H-loop/switch region; other site
1123863009184	ABC transporter; Region: ABC_tran_2; pfam12848
1123863009185	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863009186	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1123863009187	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1123863009188	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1123863009189	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1123863009190	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863009191	putative substrate translocation pore; other site
1123863009192	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863009193	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1123863009194	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863009195	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863009196	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1123863009197	transmembrane helices; other site
1123863009198	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1123863009199	manganese transport regulator MntR; Provisional; Region: PRK11050
1123863009200	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1123863009201	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1123863009202	outer membrane protein X; Provisional; Region: ompX; PRK09408
1123863009203	threonine and homoserine efflux system; Provisional; Region: PRK10532
1123863009204	EamA-like transporter family; Region: EamA; pfam00892
1123863009205	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1123863009206	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1123863009207	dimerization interface [polypeptide binding]; other site
1123863009208	DPS ferroxidase diiron center [ion binding]; other site
1123863009209	ion pore; other site
1123863009210	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1123863009211	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863009212	substrate binding pocket [chemical binding]; other site
1123863009213	membrane-bound complex binding site; other site
1123863009214	hinge residues; other site
1123863009215	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863009216	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009217	dimer interface [polypeptide binding]; other site
1123863009218	conserved gate region; other site
1123863009219	putative PBP binding loops; other site
1123863009220	ABC-ATPase subunit interface; other site
1123863009221	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1123863009222	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863009223	Walker A/P-loop; other site
1123863009224	ATP binding site [chemical binding]; other site
1123863009225	Q-loop/lid; other site
1123863009226	ABC transporter signature motif; other site
1123863009227	Walker B; other site
1123863009228	D-loop; other site
1123863009229	H-loop/switch region; other site
1123863009230	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1123863009231	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863009232	S-adenosylmethionine binding site [chemical binding]; other site
1123863009233	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863009234	NAD(P) binding site [chemical binding]; other site
1123863009235	active site
1123863009236	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1123863009237	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1123863009238	active sites [active]
1123863009239	tetramer interface [polypeptide binding]; other site
1123863009240	ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598
1123863009241	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863009242	Walker A/P-loop; other site
1123863009243	ATP binding site [chemical binding]; other site
1123863009244	Q-loop/lid; other site
1123863009245	ABC transporter signature motif; other site
1123863009246	Walker B; other site
1123863009247	D-loop; other site
1123863009248	H-loop/switch region; other site
1123863009249	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863009250	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009251	dimer interface [polypeptide binding]; other site
1123863009252	conserved gate region; other site
1123863009253	putative PBP binding loops; other site
1123863009254	ABC-ATPase subunit interface; other site
1123863009255	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863009256	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009257	dimer interface [polypeptide binding]; other site
1123863009258	conserved gate region; other site
1123863009259	putative PBP binding loops; other site
1123863009260	ABC-ATPase subunit interface; other site
1123863009261	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863009262	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863009263	substrate binding pocket [chemical binding]; other site
1123863009264	membrane-bound complex binding site; other site
1123863009265	hinge residues; other site
1123863009266	N-formylglutamate amidohydrolase; Region: FGase; cl01522
1123863009267	imidazolonepropionase; Validated; Region: PRK09356
1123863009268	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1123863009269	active site
1123863009270	N-formimino-L-glutamate deiminase; Validated; Region: PRK09229
1123863009271	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1123863009272	active site
1123863009273	HutD; Region: HutD; pfam05962
1123863009274	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
1123863009275	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863009276	DNA-binding site [nucleotide binding]; DNA binding site
1123863009277	UTRA domain; Region: UTRA; pfam07702
1123863009278	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1123863009279	active sites [active]
1123863009280	tetramer interface [polypeptide binding]; other site
1123863009281	urocanate hydratase; Provisional; Region: PRK05414
1123863009282	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863009283	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863009284	putative substrate translocation pore; other site
1123863009285	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1123863009286	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1123863009287	active site pocket [active]
1123863009288	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863009289	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863009290	DNA binding site [nucleotide binding]
1123863009291	domain linker motif; other site
1123863009292	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1123863009293	putative dimerization interface [polypeptide binding]; other site
1123863009294	putative ligand binding site [chemical binding]; other site
1123863009295	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1123863009296	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1123863009297	metal binding site [ion binding]; metal-binding site
1123863009298	putative dimer interface [polypeptide binding]; other site
1123863009299	glycosyl transferase family protein; Provisional; Region: PRK08136
1123863009300	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1123863009301	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1123863009302	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1123863009303	DEAD_2; Region: DEAD_2; pfam06733
1123863009304	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1123863009305	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863009306	Coenzyme A binding pocket [chemical binding]; other site
1123863009307	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1123863009308	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863009309	non-specific DNA binding site [nucleotide binding]; other site
1123863009310	salt bridge; other site
1123863009311	sequence-specific DNA binding site [nucleotide binding]; other site
1123863009312	Cupin domain; Region: Cupin_2; cl17218
1123863009313	transcriptional regulator MirA; Provisional; Region: PRK15043
1123863009314	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1123863009315	DNA binding residues [nucleotide binding]
1123863009316	hypothetical protein; Provisional; Region: PRK13681
1123863009317	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009318	putative PBP binding loops; other site
1123863009319	dimer interface [polypeptide binding]; other site
1123863009320	ABC-ATPase subunit interface; other site
1123863009321	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1123863009322	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1123863009323	Walker A/P-loop; other site
1123863009324	ATP binding site [chemical binding]; other site
1123863009325	Q-loop/lid; other site
1123863009326	ABC transporter signature motif; other site
1123863009327	Walker B; other site
1123863009328	D-loop; other site
1123863009329	H-loop/switch region; other site
1123863009330	CBS domain; Region: CBS; pfam00571
1123863009331	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009332	dimer interface [polypeptide binding]; other site
1123863009333	conserved gate region; other site
1123863009334	ABC-ATPase subunit interface; other site
1123863009335	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1123863009336	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1123863009337	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
1123863009338	active site
1123863009339	metal binding site [ion binding]; metal-binding site
1123863009340	nudix motif; other site
1123863009341	HAMP domain; Region: HAMP; pfam00672
1123863009342	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863009343	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863009344	dimer interface [polypeptide binding]; other site
1123863009345	putative CheW interface [polypeptide binding]; other site
1123863009346	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
1123863009347	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1123863009348	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1123863009349	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1123863009350	D-lactate dehydrogenase; Provisional; Region: PRK11183
1123863009351	FAD binding domain; Region: FAD_binding_4; pfam01565
1123863009352	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1123863009353	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264
1123863009354	Protein of unknown function (DUF3772); Region: DUF3772; pfam12607
1123863009355	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1123863009356	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1123863009357	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1123863009358	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1123863009359	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1123863009360	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1123863009361	oxidoreductase; Provisional; Region: PRK12743
1123863009362	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863009363	NAD(P) binding site [chemical binding]; other site
1123863009364	active site
1123863009365	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
1123863009366	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
1123863009367	L,D-transpeptidase; Provisional; Region: PRK10260
1123863009368	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1123863009369	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1123863009370	Uncharacterized bacterial subgroup of the Salmonella typhimurium Zn2+ transporter ZntB-like subfamily; Region: ZntB_u1; cd12834
1123863009371	Cl binding site [ion binding]; other site
1123863009372	oligomer interface [polypeptide binding]; other site
1123863009373	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1123863009374	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1123863009375	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
1123863009376	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1123863009377	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1123863009378	FMN binding site [chemical binding]; other site
1123863009379	active site
1123863009380	catalytic residues [active]
1123863009381	substrate binding site [chemical binding]; other site
1123863009382	helicase 45; Provisional; Region: PTZ00424
1123863009383	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1123863009384	ATP binding site [chemical binding]; other site
1123863009385	Mg++ binding site [ion binding]; other site
1123863009386	motif III; other site
1123863009387	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863009388	nucleotide binding region [chemical binding]; other site
1123863009389	ATP-binding site [chemical binding]; other site
1123863009390	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1123863009391	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1123863009392	putative catalytic site [active]
1123863009393	putative metal binding site [ion binding]; other site
1123863009394	putative phosphate binding site [ion binding]; other site
1123863009395	cardiolipin synthase 2; Provisional; Region: PRK11263
1123863009396	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1123863009397	putative active site [active]
1123863009398	catalytic site [active]
1123863009399	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1123863009400	putative active site [active]
1123863009401	catalytic site [active]
1123863009402	Predicted integral membrane protein [Function unknown]; Region: COG0392
1123863009403	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1123863009404	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1123863009405	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1123863009406	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1123863009407	MoaE homodimer interface [polypeptide binding]; other site
1123863009408	MoaD interaction [polypeptide binding]; other site
1123863009409	active site residues [active]
1123863009410	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1123863009411	MoaE interaction surface [polypeptide binding]; other site
1123863009412	MoeB interaction surface [polypeptide binding]; other site
1123863009413	thiocarboxylated glycine; other site
1123863009414	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1123863009415	trimer interface [polypeptide binding]; other site
1123863009416	dimer interface [polypeptide binding]; other site
1123863009417	putative active site [active]
1123863009418	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1123863009419	MPT binding site; other site
1123863009420	trimer interface [polypeptide binding]; other site
1123863009421	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1123863009422	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863009423	FeS/SAM binding site; other site
1123863009424	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1123863009425	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1123863009426	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1123863009427	phosphate binding site [ion binding]; other site
1123863009428	putative substrate binding pocket [chemical binding]; other site
1123863009429	dimer interface [polypeptide binding]; other site
1123863009430	excinuclease ABC subunit B; Provisional; Region: PRK05298
1123863009431	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863009432	ATP binding site [chemical binding]; other site
1123863009433	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863009434	nucleotide binding region [chemical binding]; other site
1123863009435	ATP-binding site [chemical binding]; other site
1123863009436	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1123863009437	UvrB/uvrC motif; Region: UVR; pfam02151
1123863009438	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1123863009439	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1123863009440	Walker A/P-loop; other site
1123863009441	ATP binding site [chemical binding]; other site
1123863009442	Q-loop/lid; other site
1123863009443	ABC transporter signature motif; other site
1123863009444	Walker B; other site
1123863009445	D-loop; other site
1123863009446	H-loop/switch region; other site
1123863009447	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1123863009448	AAA domain; Region: AAA_26; pfam13500
1123863009449	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1123863009450	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863009451	S-adenosylmethionine binding site [chemical binding]; other site
1123863009452	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
1123863009453	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1123863009454	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863009455	catalytic residue [active]
1123863009456	biotin synthase; Provisional; Region: PRK15108
1123863009457	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863009458	FeS/SAM binding site; other site
1123863009459	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1123863009460	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1123863009461	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863009462	inhibitor-cofactor binding pocket; inhibition site
1123863009463	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863009464	catalytic residue [active]
1123863009465	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1123863009466	substrate binding site [chemical binding]; other site
1123863009467	6-phosphogluconolactonase; Provisional; Region: PRK11028
1123863009468	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1123863009469	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863009470	active site
1123863009471	motif I; other site
1123863009472	motif II; other site
1123863009473	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1123863009474	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1123863009475	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863009476	Walker A/P-loop; other site
1123863009477	ATP binding site [chemical binding]; other site
1123863009478	Q-loop/lid; other site
1123863009479	ABC transporter signature motif; other site
1123863009480	Walker B; other site
1123863009481	D-loop; other site
1123863009482	H-loop/switch region; other site
1123863009483	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1123863009484	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1123863009485	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009486	dimer interface [polypeptide binding]; other site
1123863009487	conserved gate region; other site
1123863009488	putative PBP binding loops; other site
1123863009489	ABC-ATPase subunit interface; other site
1123863009490	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1123863009491	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1123863009492	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1123863009493	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1123863009494	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1123863009495	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1123863009496	TOBE domain; Region: TOBE; cl01440
1123863009497	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1123863009498	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863009499	Walker A/P-loop; other site
1123863009500	ATP binding site [chemical binding]; other site
1123863009501	Q-loop/lid; other site
1123863009502	ABC transporter signature motif; other site
1123863009503	Walker B; other site
1123863009504	D-loop; other site
1123863009505	H-loop/switch region; other site
1123863009506	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863009507	Walker A/P-loop; other site
1123863009508	ATP binding site [chemical binding]; other site
1123863009509	Q-loop/lid; other site
1123863009510	ABC transporter signature motif; other site
1123863009511	Walker B; other site
1123863009512	D-loop; other site
1123863009513	H-loop/switch region; other site
1123863009514	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1123863009515	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1123863009516	dimer interface [polypeptide binding]; other site
1123863009517	active site
1123863009518	galactokinase; Provisional; Region: PRK05101
1123863009519	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1123863009520	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1123863009521	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1123863009522	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1123863009523	active site
1123863009524	catalytic residues [active]
1123863009525	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1123863009526	catalytic core [active]
1123863009527	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1123863009528	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1123863009529	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1123863009530	YbgS-like protein; Region: YbgS; pfam13985
1123863009531	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1123863009532	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863009533	active site
1123863009534	phosphorylation site [posttranslational modification]
1123863009535	intermolecular recognition site; other site
1123863009536	dimerization interface [polypeptide binding]; other site
1123863009537	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1123863009538	DNA binding residues [nucleotide binding]
1123863009539	dimerization interface [polypeptide binding]; other site
1123863009540	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863009541	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863009542	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863009543	substrate binding pocket [chemical binding]; other site
1123863009544	membrane-bound complex binding site; other site
1123863009545	hinge residues; other site
1123863009546	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863009547	dimer interface [polypeptide binding]; other site
1123863009548	phosphorylation site [posttranslational modification]
1123863009549	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863009550	ATP binding site [chemical binding]; other site
1123863009551	Mg2+ binding site [ion binding]; other site
1123863009552	G-X-G motif; other site
1123863009553	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863009554	active site
1123863009555	phosphorylation site [posttranslational modification]
1123863009556	intermolecular recognition site; other site
1123863009557	Hpt domain; Region: Hpt; pfam01627
1123863009558	putative binding surface; other site
1123863009559	active site
1123863009560	zinc transporter ZitB; Provisional; Region: PRK03557
1123863009561	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1123863009562	quinolinate synthetase; Provisional; Region: PRK09375
1123863009563	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1123863009564	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
1123863009565	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1123863009566	DNA binding site [nucleotide binding]
1123863009567	active site
1123863009568	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
1123863009569	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1123863009570	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863009571	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1123863009572	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1123863009573	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1123863009574	minor groove reading motif; other site
1123863009575	helix-hairpin-helix signature motif; other site
1123863009576	substrate binding pocket [chemical binding]; other site
1123863009577	active site
1123863009578	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1123863009579	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863009580	dimerization interface [polypeptide binding]; other site
1123863009581	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863009582	dimer interface [polypeptide binding]; other site
1123863009583	putative CheW interface [polypeptide binding]; other site
1123863009584	tol-pal system protein YbgF; Provisional; Region: PRK10803
1123863009585	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1123863009586	TPR motif; other site
1123863009587	binding surface
1123863009588	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1123863009589	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1123863009590	ligand binding site [chemical binding]; other site
1123863009591	translocation protein TolB; Provisional; Region: tolB; PRK03629
1123863009592	TolB amino-terminal domain; Region: TolB_N; pfam04052
1123863009593	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1123863009594	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1123863009595	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1123863009596	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1123863009597	TolA C-terminal; Region: TolA; pfam06519
1123863009598	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1123863009599	colicin uptake protein TolR; Provisional; Region: PRK11024
1123863009600	colicin uptake protein TolQ; Provisional; Region: PRK10801
1123863009601	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1123863009602	active site
1123863009603	Cyd operon protein YbgE (Cyd_oper_YbgE); Region: Cyd_oper_YbgE; cl11451
1123863009604	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1123863009605	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1123863009606	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1123863009607	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1123863009608	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1123863009609	CoA binding domain; Region: CoA_binding; pfam02629
1123863009610	CoA-ligase; Region: Ligase_CoA; pfam00549
1123863009611	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1123863009612	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1123863009613	CoA-ligase; Region: Ligase_CoA; pfam00549
1123863009614	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1123863009615	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1123863009616	E3 interaction surface; other site
1123863009617	lipoyl attachment site [posttranslational modification]; other site
1123863009618	e3 binding domain; Region: E3_binding; pfam02817
1123863009619	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1123863009620	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1123863009621	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1123863009622	TPP-binding site [chemical binding]; other site
1123863009623	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1123863009624	dimer interface [polypeptide binding]; other site
1123863009625	PYR/PP interface [polypeptide binding]; other site
1123863009626	TPP binding site [chemical binding]; other site
1123863009627	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1123863009628	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1123863009629	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1123863009630	L-aspartate oxidase; Provisional; Region: PRK06175
1123863009631	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1123863009632	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1123863009633	cardiolipin binding site; other site
1123863009634	SdhC subunit interface [polypeptide binding]; other site
1123863009635	proximal heme binding site [chemical binding]; other site
1123863009636	Iron-sulfur protein interface; other site
1123863009637	proximal quinone binding site [chemical binding]; other site
1123863009638	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1123863009639	Iron-sulfur protein interface; other site
1123863009640	proximal quinone binding site [chemical binding]; other site
1123863009641	SdhD (CybS) interface [polypeptide binding]; other site
1123863009642	proximal heme binding site [chemical binding]; other site
1123863009643	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1123863009644	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1123863009645	dimer interface [polypeptide binding]; other site
1123863009646	active site
1123863009647	citrylCoA binding site [chemical binding]; other site
1123863009648	NADH binding [chemical binding]; other site
1123863009649	cationic pore residues; other site
1123863009650	oxalacetate/citrate binding site [chemical binding]; other site
1123863009651	coenzyme A binding site [chemical binding]; other site
1123863009652	catalytic triad [active]
1123863009653	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1123863009654	endonuclease VIII; Provisional; Region: PRK10445
1123863009655	N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases; Region: FpgNei_N; cl03119
1123863009656	DNA binding site [nucleotide binding]
1123863009657	catalytic residue [active]
1123863009658	H2TH interface [polypeptide binding]; other site
1123863009659	putative catalytic residues [active]
1123863009660	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1123863009661	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1123863009662	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
1123863009663	putative substrate binding pocket [chemical binding]; other site
1123863009664	AC domain interface; other site
1123863009665	catalytic triad [active]
1123863009666	AB domain interface; other site
1123863009667	interchain disulfide; other site
1123863009668	Predicted membrane protein [Function unknown]; Region: COG3817
1123863009669	Protein of unknown function (DUF979); Region: DUF979; pfam06166
1123863009670	Protein of unknown function (DUF969); Region: DUF969; pfam06149
1123863009671	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
1123863009672	putative active site [active]
1123863009673	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1123863009674	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
1123863009675	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1123863009676	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1123863009677	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
1123863009678	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1123863009679	DNA photolyase; Region: DNA_photolyase; pfam00875
1123863009680	Protein of unknown function (DUF523); Region: DUF523; pfam04463
1123863009681	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1123863009682	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1123863009683	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1123863009684	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1123863009685	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863009686	active site
1123863009687	phosphorylation site [posttranslational modification]
1123863009688	intermolecular recognition site; other site
1123863009689	dimerization interface [polypeptide binding]; other site
1123863009690	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863009691	DNA binding site [nucleotide binding]
1123863009692	phosphoglucomutase; Validated; Region: PRK07564
1123863009693	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1123863009694	active site
1123863009695	substrate binding site [chemical binding]; other site
1123863009696	metal binding site [ion binding]; metal-binding site
1123863009697	replication initiation regulator SeqA; Provisional; Region: PRK11187
1123863009698	acyl-CoA esterase; Provisional; Region: PRK10673
1123863009699	PGAP1-like protein; Region: PGAP1; pfam07819
1123863009700	LexA regulated protein; Provisional; Region: PRK11675
1123863009701	flavodoxin FldA; Validated; Region: PRK09267
1123863009702	ferric uptake regulator; Provisional; Region: fur; PRK09462
1123863009703	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1123863009704	metal binding site 2 [ion binding]; metal-binding site
1123863009705	putative DNA binding helix; other site
1123863009706	metal binding site 1 [ion binding]; metal-binding site
1123863009707	dimer interface [polypeptide binding]; other site
1123863009708	structural Zn2+ binding site [ion binding]; other site
1123863009709	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1123863009710	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1123863009711	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1123863009712	active site
1123863009713	HIGH motif; other site
1123863009714	nucleotide binding site [chemical binding]; other site
1123863009715	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1123863009716	KMSKS motif; other site
1123863009717	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1123863009718	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1123863009719	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1123863009720	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1123863009721	active site turn [active]
1123863009722	phosphorylation site [posttranslational modification]
1123863009723	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1123863009724	HPr interaction site; other site
1123863009725	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1123863009726	active site
1123863009727	phosphorylation site [posttranslational modification]
1123863009728	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1123863009729	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1123863009730	active site
1123863009731	trimer interface [polypeptide binding]; other site
1123863009732	allosteric site; other site
1123863009733	active site lid [active]
1123863009734	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1123863009735	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1123863009736	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1123863009737	active site
1123863009738	dimer interface [polypeptide binding]; other site
1123863009739	MarR family; Region: MarR; pfam01047
1123863009740	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1123863009741	ROK family; Region: ROK; pfam00480
1123863009742	UMP phosphatase; Provisional; Region: PRK10444
1123863009743	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863009744	active site
1123863009745	motif I; other site
1123863009746	motif II; other site
1123863009747	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863009748	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1123863009749	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1123863009750	active site
1123863009751	dimer interface [polypeptide binding]; other site
1123863009752	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1123863009753	Ligand Binding Site [chemical binding]; other site
1123863009754	Molecular Tunnel; other site
1123863009755	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1123863009756	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1123863009757	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1123863009758	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1123863009759	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863009760	FeS/SAM binding site; other site
1123863009761	TRAM domain; Region: TRAM; pfam01938
1123863009762	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1123863009763	PhoH-like protein; Region: PhoH; pfam02562
1123863009764	metal-binding heat shock protein; Provisional; Region: PRK00016
1123863009765	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1123863009766	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1123863009767	Transporter associated domain; Region: CorC_HlyC; smart01091
1123863009768	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1123863009769	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1123863009770	putative active site [active]
1123863009771	catalytic triad [active]
1123863009772	putative dimer interface [polypeptide binding]; other site
1123863009773	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1123863009774	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863009775	substrate binding pocket [chemical binding]; other site
1123863009776	membrane-bound complex binding site; other site
1123863009777	hinge residues; other site
1123863009778	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863009779	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009780	dimer interface [polypeptide binding]; other site
1123863009781	conserved gate region; other site
1123863009782	putative PBP binding loops; other site
1123863009783	ABC-ATPase subunit interface; other site
1123863009784	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863009785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863009786	dimer interface [polypeptide binding]; other site
1123863009787	conserved gate region; other site
1123863009788	putative PBP binding loops; other site
1123863009789	ABC-ATPase subunit interface; other site
1123863009790	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1123863009791	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863009792	Walker A/P-loop; other site
1123863009793	ATP binding site [chemical binding]; other site
1123863009794	Q-loop/lid; other site
1123863009795	ABC transporter signature motif; other site
1123863009796	Walker B; other site
1123863009797	D-loop; other site
1123863009798	H-loop/switch region; other site
1123863009799	hypothetical protein; Provisional; Region: PRK11032
1123863009800	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1123863009801	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1123863009802	HIGH motif; other site
1123863009803	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1123863009804	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1123863009805	active site
1123863009806	KMSKS motif; other site
1123863009807	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1123863009808	tRNA binding surface [nucleotide binding]; other site
1123863009809	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1123863009810	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1123863009811	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1123863009812	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1123863009813	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1123863009814	active site
1123863009815	(T/H)XGH motif; other site
1123863009816	ribosome-associated protein; Provisional; Region: PRK11538
1123863009817	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1123863009818	penicillin-binding protein 2; Provisional; Region: PRK10795
1123863009819	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1123863009820	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1123863009821	cell wall shape-determining protein; Provisional; Region: PRK10794
1123863009822	rare lipoprotein A; Provisional; Region: PRK10672
1123863009823	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1123863009824	Sporulation related domain; Region: SPOR; pfam05036
1123863009825	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1123863009826	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1123863009827	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1123863009828	hypothetical protein; Provisional; Region: PRK04998
1123863009829	lipoate-protein ligase B; Provisional; Region: PRK14342
1123863009830	lipoyl synthase; Provisional; Region: PRK05481
1123863009831	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863009832	FeS/SAM binding site; other site
1123863009833	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1123863009834	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1123863009835	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1123863009836	putative active site [active]
1123863009837	catalytic triad [active]
1123863009838	putative dimer interface [polypeptide binding]; other site
1123863009839	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863009840	Coenzyme A binding pocket [chemical binding]; other site
1123863009841	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1123863009842	DNA-binding site [nucleotide binding]; DNA binding site
1123863009843	RNA-binding motif; other site
1123863009844	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1123863009845	high-affinity gluconate transporter; Provisional; Region: PRK14984
1123863009846	gluconate transporter; Region: gntP; TIGR00791
1123863009847	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1123863009848	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1123863009849	active site
1123863009850	NAD binding site [chemical binding]; other site
1123863009851	metal binding site [ion binding]; metal-binding site
1123863009852	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1123863009853	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863009854	active site
1123863009855	motif I; other site
1123863009856	motif II; other site
1123863009857	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863009858	Domain of unknown function (DUF3315); Region: DUF3315; pfam11776
1123863009859	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863009860	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1123863009861	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1123863009862	intersubunit interface [polypeptide binding]; other site
1123863009863	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1123863009864	serine transporter; Region: stp; TIGR00814
1123863009865	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1123863009866	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1123863009867	NAD binding site [chemical binding]; other site
1123863009868	catalytic Zn binding site [ion binding]; other site
1123863009869	structural Zn binding site [ion binding]; other site
1123863009870	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1123863009871	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1123863009872	active site
1123863009873	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1123863009874	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1123863009875	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1123863009876	Cupin domain; Region: Cupin_2; cl17218
1123863009877	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1123863009878	putative lipid kinase; Reviewed; Region: PRK13057
1123863009879	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1123863009880	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1123863009881	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1123863009882	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863009883	S-adenosylmethionine binding site [chemical binding]; other site
1123863009884	Fimbrial protein; Region: Fimbrial; pfam00419
1123863009885	Fimbrial protein; Region: Fimbrial; pfam00419
1123863009886	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1123863009887	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863009888	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1123863009889	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1123863009890	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
1123863009891	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863009892	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1123863009893	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1123863009894	PapC N-terminal domain; Region: PapC_N; pfam13954
1123863009895	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1123863009896	PapC C-terminal domain; Region: PapC_C; pfam13953
1123863009897	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1123863009898	Fimbrial protein; Region: Fimbrial; cl01416
1123863009899	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1123863009900	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863009901	putative substrate translocation pore; other site
1123863009902	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863009903	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1123863009904	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1123863009905	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1123863009906	hypothetical protein; Provisional; Region: PRK09897
1123863009907	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1123863009908	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
1123863009909	Putative collagen-binding domain of a collagenase; Region: Collagen_bind_2; pfam12904
1123863009910	putative symporter YagG; Provisional; Region: PRK09669
1123863009911	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1123863009912	L-fucose isomerase and related proteins [Carbohydrate transport and metabolism]; Region: FucI; COG2407
1123863009913	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cd00578
1123863009914	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1123863009915	substrate binding site [chemical binding]; other site
1123863009916	trimer interface [polypeptide binding]; other site
1123863009917	Mn binding site [ion binding]; other site
1123863009918	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5255
1123863009919	Domain of unknown function (DUF1868); Region: 2H-phosphodiest; pfam08975
1123863009920	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1123863009921	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1123863009922	peptide binding site [polypeptide binding]; other site
1123863009923	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1123863009924	Domain of unknown function (DUF1795); Region: DUF1795; pfam08786
1123863009925	PAAR motif; Region: PAAR_motif; pfam05488
1123863009926	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1123863009927	RHS Repeat; Region: RHS_repeat; pfam05593
1123863009928	RHS Repeat; Region: RHS_repeat; cl11982
1123863009929	RHS Repeat; Region: RHS_repeat; pfam05593
1123863009930	RHS protein; Region: RHS; pfam03527
1123863009931	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1123863009932	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1123863009933	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1123863009934	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1123863009935	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1123863009936	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1123863009937	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1123863009938	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1123863009939	homodimer interface [polypeptide binding]; other site
1123863009940	NADP binding site [chemical binding]; other site
1123863009941	substrate binding site [chemical binding]; other site
1123863009942	ribosome-associated protein; Provisional; Region: PRK11507
1123863009943	Predicted ATPase [General function prediction only]; Region: COG4637
1123863009944	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863009945	Walker A/P-loop; other site
1123863009946	ATP binding site [chemical binding]; other site
1123863009947	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1123863009948	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1123863009949	active site
1123863009950	HIGH motif; other site
1123863009951	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1123863009952	KMSKS motif; other site
1123863009953	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1123863009954	tRNA binding surface [nucleotide binding]; other site
1123863009955	anticodon binding site; other site
1123863009956	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1123863009957	substrate binding site [chemical binding]; other site
1123863009958	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1123863009959	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1123863009960	putative active site [active]
1123863009961	putative metal binding site [ion binding]; other site
1123863009962	Predicted membrane protein [Function unknown]; Region: COG4325
1123863009963	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
1123863009964	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1123863009965	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1123863009966	ATP-grasp domain; Region: ATP-grasp; pfam02222
1123863009967	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1123863009968	FtsX-like permease family; Region: FtsX; pfam02687
1123863009969	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1123863009970	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1123863009971	Walker A/P-loop; other site
1123863009972	ATP binding site [chemical binding]; other site
1123863009973	Q-loop/lid; other site
1123863009974	ABC transporter signature motif; other site
1123863009975	Walker B; other site
1123863009976	D-loop; other site
1123863009977	H-loop/switch region; other site
1123863009978	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1123863009979	active site
1123863009980	catalytic triad [active]
1123863009981	oxyanion hole [active]
1123863009982	switch loop; other site
1123863009983	oxidoreductase; Provisional; Region: PRK08017
1123863009984	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1123863009985	NADP binding site [chemical binding]; other site
1123863009986	active site
1123863009987	steroid binding site; other site
1123863009988	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1123863009989	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1123863009990	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1123863009991	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1123863009992	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1123863009993	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1123863009994	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1123863009995	DNA binding residues [nucleotide binding]
1123863009996	dimer interface [polypeptide binding]; other site
1123863009997	copper binding site [ion binding]; other site
1123863009998	Uncharacterized protein family UPF0547; Region: UPF0547; pfam10571
1123863009999	copper exporting ATPase; Provisional; Region: copA; PRK10671
1123863010000	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1123863010001	metal-binding site [ion binding]
1123863010002	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1123863010003	metal-binding site [ion binding]
1123863010004	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1123863010005	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863010006	motif II; other site
1123863010007	TraB family; Region: TraB; cl12050
1123863010008	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1123863010009	putative deacylase active site [active]
1123863010010	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863010011	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863010012	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1123863010013	dimerization interface [polypeptide binding]; other site
1123863010014	Predicted membrane protein [Function unknown]; Region: COG4125
1123863010015	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1123863010016	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1123863010017	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1123863010018	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1123863010019	active site
1123863010020	metal binding site [ion binding]; metal-binding site
1123863010021	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1123863010022	putative cation:proton antiport protein; Provisional; Region: PRK10669
1123863010023	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1123863010024	TrkA-N domain; Region: TrkA_N; pfam02254
1123863010025	inosine/guanosine kinase; Provisional; Region: PRK15074
1123863010026	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863010027	adenylate kinase; Reviewed; Region: adk; PRK00279
1123863010028	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1123863010029	AMP-binding site [chemical binding]; other site
1123863010030	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1123863010031	heat shock protein 90; Provisional; Region: PRK05218
1123863010032	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863010033	ATP binding site [chemical binding]; other site
1123863010034	Mg2+ binding site [ion binding]; other site
1123863010035	G-X-G motif; other site
1123863010036	recombination protein RecR; Reviewed; Region: recR; PRK00076
1123863010037	RecR protein; Region: RecR; pfam02132
1123863010038	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1123863010039	putative active site [active]
1123863010040	putative metal-binding site [ion binding]; other site
1123863010041	tetramer interface [polypeptide binding]; other site
1123863010042	hypothetical protein; Validated; Region: PRK00153
1123863010043	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1123863010044	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863010045	Walker A motif; other site
1123863010046	ATP binding site [chemical binding]; other site
1123863010047	Walker B motif; other site
1123863010048	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1123863010049	arginine finger; other site
1123863010050	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1123863010051	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1123863010052	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1123863010053	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1123863010054	active site
1123863010055	hypothetical protein; Provisional; Region: PRK10527
1123863010056	Primosomal replication protein priB and priC; Region: priB_priC; cl11483
1123863010057	hypothetical protein; Provisional; Region: PRK11038
1123863010058	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1123863010059	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863010060	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1123863010061	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1123863010062	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863010063	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863010064	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1123863010065	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1123863010066	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1123863010067	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1123863010068	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1123863010069	metal binding site [ion binding]; metal-binding site
1123863010070	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1123863010071	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863010072	ABC-ATPase subunit  interface; other site
1123863010073	dimer interface [polypeptide binding]; other site
1123863010074	putative PBP binding regions; other site
1123863010075	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1123863010076	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1123863010077	Hha toxicity attenuator; Provisional; Region: PRK10667
1123863010078	gene expression modulator; Provisional; Region: PRK10945
1123863010079	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1123863010080	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1123863010081	DNA binding site [nucleotide binding]
1123863010082	active site
1123863010083	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1123863010084	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1123863010085	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1123863010086	active site
1123863010087	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1123863010088	catalytic triad [active]
1123863010089	dimer interface [polypeptide binding]; other site
1123863010090	ammonium transporter; Provisional; Region: PRK10666
1123863010091	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1123863010092	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1123863010093	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1123863010094	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1123863010095	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863010096	Walker A/P-loop; other site
1123863010097	ATP binding site [chemical binding]; other site
1123863010098	Q-loop/lid; other site
1123863010099	ABC transporter signature motif; other site
1123863010100	Walker B; other site
1123863010101	D-loop; other site
1123863010102	H-loop/switch region; other site
1123863010103	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1123863010104	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1123863010105	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863010106	Walker A/P-loop; other site
1123863010107	ATP binding site [chemical binding]; other site
1123863010108	Q-loop/lid; other site
1123863010109	ABC transporter signature motif; other site
1123863010110	Walker B; other site
1123863010111	D-loop; other site
1123863010112	H-loop/switch region; other site
1123863010113	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1123863010114	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863010115	putative DNA binding site [nucleotide binding]; other site
1123863010116	putative Zn2+ binding site [ion binding]; other site
1123863010117	AsnC family; Region: AsnC_trans_reg; pfam01037
1123863010118	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1123863010119	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1123863010120	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863010121	catalytic residue [active]
1123863010122	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1123863010123	Ligand Binding Site [chemical binding]; other site
1123863010124	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1123863010125	active site
1123863010126	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1123863010127	periplasmic folding chaperone; Provisional; Region: PRK10788
1123863010128	SurA N-terminal domain; Region: SurA_N_3; cl07813
1123863010129	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1123863010130	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1123863010131	IHF dimer interface [polypeptide binding]; other site
1123863010132	IHF - DNA interface [nucleotide binding]; other site
1123863010133	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1123863010134	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1123863010135	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1123863010136	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863010137	Walker A motif; other site
1123863010138	ATP binding site [chemical binding]; other site
1123863010139	Walker B motif; other site
1123863010140	arginine finger; other site
1123863010141	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1123863010142	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1123863010143	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1123863010144	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863010145	Walker A motif; other site
1123863010146	ATP binding site [chemical binding]; other site
1123863010147	Walker B motif; other site
1123863010148	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1123863010149	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1123863010150	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1123863010151	oligomer interface [polypeptide binding]; other site
1123863010152	active site residues [active]
1123863010153	trigger factor; Provisional; Region: tig; PRK01490
1123863010154	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1123863010155	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1123863010156	transcriptional regulator BolA; Provisional; Region: PRK11628
1123863010157	hypothetical protein; Provisional; Region: PRK11627
1123863010158	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1123863010159	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1123863010160	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863010161	putative substrate translocation pore; other site
1123863010162	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1123863010163	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1123863010164	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1123863010165	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1123863010166	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1123863010167	D-pathway; other site
1123863010168	Putative ubiquinol binding site [chemical binding]; other site
1123863010169	Low-spin heme (heme b) binding site [chemical binding]; other site
1123863010170	Putative water exit pathway; other site
1123863010171	Binuclear center (heme o3/CuB) [ion binding]; other site
1123863010172	K-pathway; other site
1123863010173	Putative proton exit pathway; other site
1123863010174	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1123863010175	Subunit I/III interface [polypeptide binding]; other site
1123863010176	Subunit III/IV interface [polypeptide binding]; other site
1123863010177	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1123863010178	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1123863010179	UbiA prenyltransferase family; Region: UbiA; pfam01040
1123863010180	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863010181	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863010182	putative substrate translocation pore; other site
1123863010183	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1123863010184	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1123863010185	NAD binding site [chemical binding]; other site
1123863010186	substrate binding site [chemical binding]; other site
1123863010187	catalytic Zn binding site [ion binding]; other site
1123863010188	tetramer interface [polypeptide binding]; other site
1123863010189	structural Zn binding site [ion binding]; other site
1123863010190	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1123863010191	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1123863010192	NAD(P) binding site [chemical binding]; other site
1123863010193	catalytic residues [active]
1123863010194	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
1123863010195	GAF domain; Region: GAF; pfam01590
1123863010196	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863010197	Walker A motif; other site
1123863010198	ATP binding site [chemical binding]; other site
1123863010199	Walker B motif; other site
1123863010200	arginine finger; other site
1123863010201	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1123863010202	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1123863010203	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1123863010204	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1123863010205	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1123863010206	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1123863010207	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1123863010208	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1123863010209	conserved cys residue [active]
1123863010210	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1123863010211	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1123863010212	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1123863010213	Ligand Binding Site [chemical binding]; other site
1123863010214	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1123863010215	active site residue [active]
1123863010216	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1123863010217	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1123863010218	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1123863010219	substrate binding pocket [chemical binding]; other site
1123863010220	chain length determination region; other site
1123863010221	substrate-Mg2+ binding site; other site
1123863010222	catalytic residues [active]
1123863010223	aspartate-rich region 1; other site
1123863010224	active site lid residues [active]
1123863010225	aspartate-rich region 2; other site
1123863010226	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1123863010227	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1123863010228	TPP-binding site; other site
1123863010229	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1123863010230	PYR/PP interface [polypeptide binding]; other site
1123863010231	dimer interface [polypeptide binding]; other site
1123863010232	TPP binding site [chemical binding]; other site
1123863010233	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1123863010234	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1123863010235	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1123863010236	active site
1123863010237	catalytic tetrad [active]
1123863010238	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1123863010239	tetramer interfaces [polypeptide binding]; other site
1123863010240	binuclear metal-binding site [ion binding]; other site
1123863010241	thiamine monophosphate kinase; Provisional; Region: PRK05731
1123863010242	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1123863010243	ATP binding site [chemical binding]; other site
1123863010244	dimerization interface [polypeptide binding]; other site
1123863010245	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1123863010246	putative RNA binding site [nucleotide binding]; other site
1123863010247	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1123863010248	homopentamer interface [polypeptide binding]; other site
1123863010249	active site
1123863010250	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1123863010251	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1123863010252	catalytic motif [active]
1123863010253	Zn binding site [ion binding]; other site
1123863010254	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1123863010255	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1123863010256	ATP cone domain; Region: ATP-cone; pfam03477
1123863010257	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863010258	hypothetical protein; Provisional; Region: PRK11530
1123863010259	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1123863010260	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1123863010261	Protein export membrane protein; Region: SecD_SecF; pfam02355
1123863010262	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1123863010263	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1123863010264	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1123863010265	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1123863010266	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1123863010267	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1123863010268	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1123863010269	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1123863010270	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1123863010271	Protein of unknown function, DUF479; Region: DUF479; cl01203
1123863010272	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1123863010273	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1123863010274	active site
1123863010275	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1123863010276	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1123863010277	catalytic core [active]
1123863010278	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1123863010279	putative proline-specific permease; Provisional; Region: proY; PRK10580
1123863010280	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
1123863010281	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1123863010282	substrate binding site [chemical binding]; other site
1123863010283	THF binding site; other site
1123863010284	zinc-binding site [ion binding]; other site
1123863010285	PBP superfamily domain; Region: PBP_like_2; cl17296
1123863010286	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1123863010287	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1123863010288	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863010289	putative active site [active]
1123863010290	heme pocket [chemical binding]; other site
1123863010291	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863010292	dimer interface [polypeptide binding]; other site
1123863010293	phosphorylation site [posttranslational modification]
1123863010294	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863010295	ATP binding site [chemical binding]; other site
1123863010296	Mg2+ binding site [ion binding]; other site
1123863010297	G-X-G motif; other site
1123863010298	transcriptional regulator PhoB; Provisional; Region: PRK10161
1123863010299	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863010300	active site
1123863010301	phosphorylation site [posttranslational modification]
1123863010302	intermolecular recognition site; other site
1123863010303	dimerization interface [polypeptide binding]; other site
1123863010304	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863010305	DNA binding site [nucleotide binding]
1123863010306	exonuclease subunit SbcD; Provisional; Region: PRK10966
1123863010307	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1123863010308	active site
1123863010309	metal binding site [ion binding]; metal-binding site
1123863010310	DNA binding site [nucleotide binding]
1123863010311	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1123863010312	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863010313	AAA domain; Region: AAA_23; pfam13476
1123863010314	Walker A/P-loop; other site
1123863010315	ATP binding site [chemical binding]; other site
1123863010316	Q-loop/lid; other site
1123863010317	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863010318	ABC transporter signature motif; other site
1123863010319	Walker B; other site
1123863010320	D-loop; other site
1123863010321	H-loop/switch region; other site
1123863010322	TolA C-terminal; Region: TolA; pfam06519
1123863010323	fructokinase; Reviewed; Region: PRK09557
1123863010324	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1123863010325	nucleotide binding site [chemical binding]; other site
1123863010326	recombination associated protein; Reviewed; Region: rdgC; PRK00321
1123863010327	hypothetical protein; Provisional; Region: PRK10579
1123863010328	hypothetical protein; Provisional; Region: PRK10380
1123863010329	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1123863010330	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1123863010331	ADP binding site [chemical binding]; other site
1123863010332	magnesium binding site [ion binding]; other site
1123863010333	putative shikimate binding site; other site
1123863010334	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
1123863010335	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
1123863010336	hypothetical protein; Validated; Region: PRK00124
1123863010337	pyrroline-5-carboxylate reductase; Region: PLN02688
1123863010338	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1123863010339	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1123863010340	iron-sulfur cluster [ion binding]; other site
1123863010341	[2Fe-2S] cluster binding site [ion binding]; other site
1123863010342	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1123863010343	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863010344	psiF repeat; Region: PsiF_repeat; pfam07769
1123863010345	psiF repeat; Region: PsiF_repeat; pfam07769
1123863010346	anti-RssB factor; Provisional; Region: PRK10244
1123863010347	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1123863010348	Peptidase inhibitor I78 family; Region: Inhibitor_I78; pfam11720
1123863010349	CAAX protease self-immunity; Region: Abi; pfam02517
1123863010350	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863010351	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863010352	DNA binding site [nucleotide binding]
1123863010353	domain linker motif; other site
1123863010354	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1123863010355	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1123863010356	beta-galactosidase; Region: BGL; TIGR03356
1123863010357	PTS system, Lactose/Cellobiose specific IIA subunit; Region: PTS_IIA; pfam02255
1123863010358	active site
1123863010359	methionine cluster; other site
1123863010360	phosphorylation site [posttranslational modification]
1123863010361	metal binding site [ion binding]; metal-binding site
1123863010362	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1123863010363	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1123863010364	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1123863010365	active site
1123863010366	P-loop; other site
1123863010367	phosphorylation site [posttranslational modification]
1123863010368	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1123863010369	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1123863010370	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1123863010371	phosphate binding site [ion binding]; other site
1123863010372	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1123863010373	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863010374	DNA-binding site [nucleotide binding]; DNA binding site
1123863010375	FCD domain; Region: FCD; pfam07729
1123863010376	L-lactate permease; Provisional; Region: PRK10420
1123863010377	glycolate transporter; Provisional; Region: PRK09695
1123863010378	putative cyanate transporter; Provisional; Region: cynX; PRK09705
1123863010379	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863010380	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863010381	dimerization interface [polypeptide binding]; other site
1123863010382	putative deaminase; Validated; Region: PRK06846
1123863010383	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1123863010384	active site
1123863010385	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1123863010386	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1123863010387	ATP binding site [chemical binding]; other site
1123863010388	Mg++ binding site [ion binding]; other site
1123863010389	motif III; other site
1123863010390	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863010391	nucleotide binding region [chemical binding]; other site
1123863010392	ATP-binding site [chemical binding]; other site
1123863010393	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1123863010394	putative RNA binding site [nucleotide binding]; other site
1123863010395	Bacterial OB fold (BOF) protein; Region: BOF; cl01196
1123863010396	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1123863010397	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1123863010398	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863010399	active site
1123863010400	phosphorylation site [posttranslational modification]
1123863010401	intermolecular recognition site; other site
1123863010402	dimerization interface [polypeptide binding]; other site
1123863010403	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1123863010404	DNA-binding site [nucleotide binding]; DNA binding site
1123863010405	RNA-binding motif; other site
1123863010406	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1123863010407	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1123863010408	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863010409	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863010410	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863010411	dimerization interface [polypeptide binding]; other site
1123863010412	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1123863010413	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1123863010414	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1123863010415	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1123863010416	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1123863010417	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1123863010418	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1123863010419	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
1123863010420	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
1123863010421	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1123863010422	dimerization domain swap beta strand [polypeptide binding]; other site
1123863010423	regulatory protein interface [polypeptide binding]; other site
1123863010424	active site
1123863010425	regulatory phosphorylation site [posttranslational modification]; other site
1123863010426	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1123863010427	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1123863010428	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
1123863010429	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
1123863010430	Dak1 domain; Region: Dak1; pfam02733
1123863010431	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1123863010432	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1123863010433	dimer interface [polypeptide binding]; other site
1123863010434	active site
1123863010435	metal binding site [ion binding]; metal-binding site
1123863010436	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
1123863010437	PAS domain; Region: PAS; smart00091
1123863010438	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863010439	Walker A motif; other site
1123863010440	ATP binding site [chemical binding]; other site
1123863010441	Walker B motif; other site
1123863010442	arginine finger; other site
1123863010443	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1123863010444	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
1123863010445	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1123863010446	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1123863010447	catalytic residue [active]
1123863010448	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1123863010449	non-specific DNA binding site [nucleotide binding]; other site
1123863010450	salt bridge; other site
1123863010451	sequence-specific DNA binding site [nucleotide binding]; other site
1123863010452	Predicted transcriptional regulator [Transcription]; Region: COG2932
1123863010453	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1123863010454	Catalytic site [active]
1123863010455	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1123863010456	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1123863010457	putative catalytic cysteine [active]
1123863010458	gamma-glutamyl kinase; Provisional; Region: PRK05429
1123863010459	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1123863010460	nucleotide binding site [chemical binding]; other site
1123863010461	homotetrameric interface [polypeptide binding]; other site
1123863010462	putative phosphate binding site [ion binding]; other site
1123863010463	putative allosteric binding site; other site
1123863010464	PUA domain; Region: PUA; pfam01472
1123863010465	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1123863010466	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1123863010467	trimer interface [polypeptide binding]; other site
1123863010468	eyelet of channel; other site
1123863010469	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1123863010470	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1123863010471	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1123863010472	active site
1123863010473	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1123863010474	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1123863010475	metal binding site [ion binding]; metal-binding site
1123863010476	dimer interface [polypeptide binding]; other site
1123863010477	Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423
1123863010478	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
1123863010479	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1123863010480	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1123863010481	tetramer interface [polypeptide binding]; other site
1123863010482	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863010483	catalytic residue [active]
1123863010484	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863010485	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863010486	Walker A/P-loop; other site
1123863010487	ATP binding site [chemical binding]; other site
1123863010488	Q-loop/lid; other site
1123863010489	ABC transporter signature motif; other site
1123863010490	Walker B; other site
1123863010491	D-loop; other site
1123863010492	H-loop/switch region; other site
1123863010493	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863010494	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863010495	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863010496	TM-ABC transporter signature motif; other site
1123863010497	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
1123863010498	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1123863010499	putative ligand binding site [chemical binding]; other site
1123863010500	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1123863010501	active site
1123863010502	DNA polymerase IV; Validated; Region: PRK02406
1123863010503	DNA binding site [nucleotide binding]
1123863010504	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1123863010505	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1123863010506	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1123863010507	putative active site [active]
1123863010508	putative dimer interface [polypeptide binding]; other site
1123863010509	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1123863010510	dimer interface [polypeptide binding]; other site
1123863010511	active site
1123863010512	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1123863010513	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1123863010514	active site
1123863010515	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1123863010516	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1123863010517	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
1123863010518	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1123863010519	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
1123863010520	Cupin domain; Region: Cupin_2; cl17218
1123863010521	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
1123863010522	intersubunit interface [polypeptide binding]; other site
1123863010523	active site
1123863010524	Zn2+ binding site [ion binding]; other site
1123863010525	methionine aminotransferase; Validated; Region: PRK09082
1123863010526	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863010527	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863010528	homodimer interface [polypeptide binding]; other site
1123863010529	catalytic residue [active]
1123863010530	C-N hydrolase family amidase; Provisional; Region: PRK10438
1123863010531	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1123863010532	putative active site [active]
1123863010533	catalytic triad [active]
1123863010534	dimer interface [polypeptide binding]; other site
1123863010535	multimer interface [polypeptide binding]; other site
1123863010536	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1123863010537	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1123863010538	heme binding site [chemical binding]; other site
1123863010539	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1123863010540	heme binding site [chemical binding]; other site
1123863010541	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1123863010542	active site
1123863010543	homotetramer interface [polypeptide binding]; other site
1123863010544	OHCU decarboxylase; Region: UraD_2; TIGR03180
1123863010545	allantoate amidohydrolase; Reviewed; Region: PRK09290
1123863010546	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1123863010547	active site
1123863010548	metal binding site [ion binding]; metal-binding site
1123863010549	dimer interface [polypeptide binding]; other site
1123863010550	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1123863010551	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1123863010552	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863010553	catalytic residue [active]
1123863010554	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1123863010555	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863010556	Walker A/P-loop; other site
1123863010557	ATP binding site [chemical binding]; other site
1123863010558	Q-loop/lid; other site
1123863010559	ABC transporter signature motif; other site
1123863010560	Walker B; other site
1123863010561	D-loop; other site
1123863010562	H-loop/switch region; other site
1123863010563	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
1123863010564	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863010565	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863010566	dimer interface [polypeptide binding]; other site
1123863010567	conserved gate region; other site
1123863010568	putative PBP binding loops; other site
1123863010569	ABC-ATPase subunit interface; other site
1123863010570	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863010571	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863010572	substrate binding pocket [chemical binding]; other site
1123863010573	membrane-bound complex binding site; other site
1123863010574	hinge residues; other site
1123863010575	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1123863010576	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863010577	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1123863010578	putative active site [active]
1123863010579	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1123863010580	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1123863010581	Protein of unknown function (DUF4089); Region: DUF4089; pfam13318
1123863010582	amidase; Provisional; Region: PRK09201
1123863010583	Amidase; Region: Amidase; pfam01425
1123863010584	Protein of unknown function (DUF3225); Region: DUF3225; pfam11533
1123863010585	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1123863010586	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863010587	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1123863010588	dimerization interface [polypeptide binding]; other site
1123863010589	substrate binding pocket [chemical binding]; other site
1123863010590	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
1123863010591	acetylornithine deacetylase; Provisional; Region: PRK07522
1123863010592	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1123863010593	metal binding site [ion binding]; metal-binding site
1123863010594	putative dimer interface [polypeptide binding]; other site
1123863010595	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
1123863010596	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1123863010597	homotrimer interaction site [polypeptide binding]; other site
1123863010598	putative active site [active]
1123863010599	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863010600	flavin-dependent oxidoreductase, MSMEG_0569 family; Region: MSMEG_0569_nitr; TIGR04046
1123863010601	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863010602	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863010603	The C-terminal substrate-binding domain of putative LysR-type transcriptional regulator PAO1-like, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_PAO1_like; cd08412
1123863010604	putative substrate binding pocket [chemical binding]; other site
1123863010605	dimerization interface [polypeptide binding]; other site
1123863010606	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1123863010607	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863010608	dimer interface [polypeptide binding]; other site
1123863010609	conserved gate region; other site
1123863010610	putative PBP binding loops; other site
1123863010611	ABC-ATPase subunit interface; other site
1123863010612	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1123863010613	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863010614	Walker A/P-loop; other site
1123863010615	ATP binding site [chemical binding]; other site
1123863010616	Q-loop/lid; other site
1123863010617	ABC transporter signature motif; other site
1123863010618	Walker B; other site
1123863010619	D-loop; other site
1123863010620	H-loop/switch region; other site
1123863010621	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721
1123863010622	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863010623	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863010624	substrate binding pocket [chemical binding]; other site
1123863010625	membrane-bound complex binding site; other site
1123863010626	hinge residues; other site
1123863010627	hypothetical protein; Provisional; Region: PRK07490
1123863010628	intersubunit interface [polypeptide binding]; other site
1123863010629	active site
1123863010630	Zn2+ binding site [ion binding]; other site
1123863010631	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
1123863010632	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
1123863010633	active site
1123863010634	catalytic site [active]
1123863010635	tetramer interface [polypeptide binding]; other site
1123863010636	Hydantoin racemase [Amino acid transport and metabolism]; Region: COG4126
1123863010637	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1123863010638	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863010639	DNA-binding site [nucleotide binding]; DNA binding site
1123863010640	FCD domain; Region: FCD; pfam07729
1123863010641	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555
1123863010642	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1123863010643	Na binding site [ion binding]; other site
1123863010644	putative substrate binding site [chemical binding]; other site
1123863010645	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
1123863010646	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
1123863010647	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1123863010648	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1123863010649	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
1123863010650	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1123863010651	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1123863010652	putative NAD(P) binding site [chemical binding]; other site
1123863010653	active site
1123863010654	Glucitol operon activator protein (GutM); Region: GutM; cl01890
1123863010655	potential protein location (hypothetical protein) that overlaps protein (sorbitol operon activator protein)
1123863010656	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1123863010657	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1123863010658	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863010659	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1123863010660	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1123863010661	putative active site [active]
1123863010662	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1123863010663	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1123863010664	active site
1123863010665	intersubunit interactions; other site
1123863010666	catalytic residue [active]
1123863010667	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1123863010668	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1123863010669	active site
1123863010670	catalytic site [active]
1123863010671	substrate binding site [chemical binding]; other site
1123863010672	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1123863010673	RNA/DNA hybrid binding site [nucleotide binding]; other site
1123863010674	active site
1123863010675	Methyltransferase domain; Region: Methyltransf_11; pfam08241
1123863010676	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1123863010677	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1123863010678	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1123863010679	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1123863010680	catalytic residue [active]
1123863010681	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1123863010682	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1123863010683	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1123863010684	hypothetical protein; Provisional; Region: PRK05421
1123863010685	putative catalytic site [active]
1123863010686	putative metal binding site [ion binding]; other site
1123863010687	putative phosphate binding site [ion binding]; other site
1123863010688	putative catalytic site [active]
1123863010689	putative phosphate binding site [ion binding]; other site
1123863010690	putative metal binding site [ion binding]; other site
1123863010691	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863010692	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863010693	dimerization interface [polypeptide binding]; other site
1123863010694	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
1123863010695	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863010696	active site
1123863010697	motif I; other site
1123863010698	motif II; other site
1123863010699	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1123863010700	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1123863010701	Walker A/P-loop; other site
1123863010702	ATP binding site [chemical binding]; other site
1123863010703	Q-loop/lid; other site
1123863010704	ABC transporter signature motif; other site
1123863010705	Walker B; other site
1123863010706	D-loop; other site
1123863010707	H-loop/switch region; other site
1123863010708	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1123863010709	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863010710	dimer interface [polypeptide binding]; other site
1123863010711	conserved gate region; other site
1123863010712	ABC-ATPase subunit interface; other site
1123863010713	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1123863010714	lipoprotein, YaeC family; Region: TIGR00363
1123863010715	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1123863010716	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1123863010717	homodimer interaction site [polypeptide binding]; other site
1123863010718	cofactor binding site; other site
1123863010719	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1123863010720	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1123863010721	dimer interface [polypeptide binding]; other site
1123863010722	motif 1; other site
1123863010723	active site
1123863010724	motif 2; other site
1123863010725	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1123863010726	putative deacylase active site [active]
1123863010727	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1123863010728	active site
1123863010729	motif 3; other site
1123863010730	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1123863010731	anticodon binding site; other site
1123863010732	hypothetical protein; Provisional; Region: PRK09256
1123863010733	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1123863010734	hypothetical protein; Provisional; Region: PRK04964
1123863010735	Modulator of Rho-dependent transcription termination (ROF); Region: ROF; cl09210
1123863010736	Cytochrome c; Region: Cytochrom_C; cl11414
1123863010737	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1123863010738	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1123863010739	Ligand Binding Site [chemical binding]; other site
1123863010740	TilS substrate binding domain; Region: TilS; pfam09179
1123863010741	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1123863010742	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1123863010743	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863010744	putative metal binding site [ion binding]; other site
1123863010745	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1123863010746	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1123863010747	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1123863010748	homodimer interface [polypeptide binding]; other site
1123863010749	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863010750	catalytic residue [active]
1123863010751	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1123863010752	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1123863010753	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1123863010754	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1123863010755	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1123863010756	putative active site [active]
1123863010757	putative PHP Thumb interface [polypeptide binding]; other site
1123863010758	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1123863010759	generic binding surface II; other site
1123863010760	generic binding surface I; other site
1123863010761	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1123863010762	RNA/DNA hybrid binding site [nucleotide binding]; other site
1123863010763	active site
1123863010764	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1123863010765	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1123863010766	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1123863010767	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1123863010768	active site
1123863010769	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1123863010770	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1123863010771	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1123863010772	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1123863010773	trimer interface [polypeptide binding]; other site
1123863010774	active site
1123863010775	UDP-GlcNAc binding site [chemical binding]; other site
1123863010776	lipid binding site [chemical binding]; lipid-binding site
1123863010777	periplasmic chaperone; Provisional; Region: PRK10780
1123863010778	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1123863010779	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1123863010780	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1123863010781	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1123863010782	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1123863010783	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1123863010784	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1123863010785	Surface antigen; Region: Bac_surface_Ag; pfam01103
1123863010786	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1123863010787	active site
1123863010788	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1123863010789	protein binding site [polypeptide binding]; other site
1123863010790	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1123863010791	protein binding site [polypeptide binding]; other site
1123863010792	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1123863010793	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1123863010794	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1123863010795	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1123863010796	catalytic residue [active]
1123863010797	putative FPP diphosphate  binding site; other site
1123863010798	putative FPP binding hydrophobic cleft; other site
1123863010799	dimer interface [polypeptide binding]; other site
1123863010800	putative IPP diphosphate binding site; other site
1123863010801	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1123863010802	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1123863010803	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1123863010804	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1123863010805	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1123863010806	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1123863010807	hinge region; other site
1123863010808	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1123863010809	putative nucleotide binding site [chemical binding]; other site
1123863010810	uridine monophosphate binding site [chemical binding]; other site
1123863010811	homohexameric interface [polypeptide binding]; other site
1123863010812	elongation factor Ts; Provisional; Region: tsf; PRK09377
1123863010813	UBA/TS-N domain; Region: UBA; pfam00627
1123863010814	Elongation factor TS; Region: EF_TS; pfam00889
1123863010815	Elongation factor TS; Region: EF_TS; pfam00889
1123863010816	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1123863010817	rRNA interaction site [nucleotide binding]; other site
1123863010818	S8 interaction site; other site
1123863010819	putative laminin-1 binding site; other site
1123863010820	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1123863010821	active site
1123863010822	PII uridylyl-transferase; Provisional; Region: PRK05007
1123863010823	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1123863010824	metal binding triad; other site
1123863010825	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1123863010826	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1123863010827	Zn2+ binding site [ion binding]; other site
1123863010828	Mg2+ binding site [ion binding]; other site
1123863010829	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1123863010830	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1123863010831	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1123863010832	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1123863010833	trimer interface [polypeptide binding]; other site
1123863010834	active site
1123863010835	substrate binding site [chemical binding]; other site
1123863010836	CoA binding site [chemical binding]; other site
1123863010837	hypothetical protein; Provisional; Region: PRK13677
1123863010838	Alginate lyase; Region: Alginate_lyase; pfam05426
1123863010839	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1123863010840	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1123863010841	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1123863010842	serine endoprotease; Provisional; Region: PRK10942
1123863010843	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1123863010844	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1123863010845	protein binding site [polypeptide binding]; other site
1123863010846	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1123863010847	protein binding site [polypeptide binding]; other site
1123863010848	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1123863010849	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1123863010850	Zn2+ binding site [ion binding]; other site
1123863010851	Mg2+ binding site [ion binding]; other site
1123863010852	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1123863010853	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1123863010854	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1123863010855	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1123863010856	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1123863010857	cobalamin binding residues [chemical binding]; other site
1123863010858	putative BtuC binding residues; other site
1123863010859	dimer interface [polypeptide binding]; other site
1123863010860	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1123863010861	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1123863010862	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863010863	inhibitor-cofactor binding pocket; inhibition site
1123863010864	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863010865	catalytic residue [active]
1123863010866	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1123863010867	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863010868	ABC-ATPase subunit  interface; other site
1123863010869	dimer interface [polypeptide binding]; other site
1123863010870	putative PBP binding regions; other site
1123863010871	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863010872	ABC-ATPase subunit  interface; other site
1123863010873	dimer interface [polypeptide binding]; other site
1123863010874	putative PBP binding regions; other site
1123863010875	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1123863010876	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1123863010877	siderophore binding site; other site
1123863010878	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1123863010879	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1123863010880	Walker A/P-loop; other site
1123863010881	ATP binding site [chemical binding]; other site
1123863010882	Q-loop/lid; other site
1123863010883	ABC transporter signature motif; other site
1123863010884	Walker B; other site
1123863010885	D-loop; other site
1123863010886	H-loop/switch region; other site
1123863010887	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1123863010888	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863010889	N-terminal plug; other site
1123863010890	ligand-binding site [chemical binding]; other site
1123863010891	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1123863010892	Transglycosylase; Region: Transgly; pfam00912
1123863010893	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1123863010894	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1123863010895	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863010896	ATP binding site [chemical binding]; other site
1123863010897	putative Mg++ binding site [ion binding]; other site
1123863010898	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863010899	nucleotide binding region [chemical binding]; other site
1123863010900	ATP-binding site [chemical binding]; other site
1123863010901	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1123863010902	2'-5' RNA ligase; Provisional; Region: PRK15124
1123863010903	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1123863010904	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1123863010905	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1123863010906	glutamyl-queuosine tRNA(Asp) synthetase; Region: queuosine_YadB; TIGR03838
1123863010907	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1123863010908	active site
1123863010909	nucleotide binding site [chemical binding]; other site
1123863010910	HIGH motif; other site
1123863010911	KMSKS motif; other site
1123863010912	poly(A) polymerase; Region: pcnB; TIGR01942
1123863010913	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1123863010914	active site
1123863010915	NTP binding site [chemical binding]; other site
1123863010916	metal binding triad [ion binding]; metal-binding site
1123863010917	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1123863010918	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1123863010919	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1123863010920	catalytic center binding site [active]
1123863010921	ATP binding site [chemical binding]; other site
1123863010922	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1123863010923	oligomerization interface [polypeptide binding]; other site
1123863010924	active site
1123863010925	metal binding site [ion binding]; metal-binding site
1123863010926	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1123863010927	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1123863010928	active site
1123863010929	ATP-binding site [chemical binding]; other site
1123863010930	pantoate-binding site; other site
1123863010931	HXXH motif; other site
1123863010932	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1123863010933	tetramerization interface [polypeptide binding]; other site
1123863010934	active site
1123863010935	inner membrane transport permease; Provisional; Region: PRK15066
1123863010936	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1123863010937	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1123863010938	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1123863010939	Walker A/P-loop; other site
1123863010940	ATP binding site [chemical binding]; other site
1123863010941	Q-loop/lid; other site
1123863010942	ABC transporter signature motif; other site
1123863010943	Walker B; other site
1123863010944	D-loop; other site
1123863010945	H-loop/switch region; other site
1123863010946	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1123863010947	active site clefts [active]
1123863010948	zinc binding site [ion binding]; other site
1123863010949	dimer interface [polypeptide binding]; other site
1123863010950	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1123863010951	active site
1123863010952	methionine gamma-lyase; Validated; Region: PRK07049
1123863010953	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1123863010954	homodimer interface [polypeptide binding]; other site
1123863010955	substrate-cofactor binding pocket; other site
1123863010956	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863010957	catalytic residue [active]
1123863010958	multicopper oxidase; Provisional; Region: PRK10965
1123863010959	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1123863010960	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1123863010961	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1123863010962	spermidine synthase; Provisional; Region: PRK00811
1123863010963	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863010964	S-adenosylmethionine binding site [chemical binding]; other site
1123863010965	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1123863010966	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1123863010967	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1123863010968	active site
1123863010969	TDP-binding site; other site
1123863010970	acceptor substrate-binding pocket; other site
1123863010971	CHASE3 domain; Region: CHASE3; pfam05227
1123863010972	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1123863010973	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863010974	dimerization interface [polypeptide binding]; other site
1123863010975	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863010976	dimer interface [polypeptide binding]; other site
1123863010977	putative CheW interface [polypeptide binding]; other site
1123863010978	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1123863010979	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
1123863010980	hypothetical protein; Provisional; Region: PRK05248
1123863010981	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1123863010982	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1123863010983	substrate binding site [chemical binding]; other site
1123863010984	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1123863010985	substrate binding site [chemical binding]; other site
1123863010986	ligand binding site [chemical binding]; other site
1123863010987	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1123863010988	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1123863010989	active site
1123863010990	catalytic tetrad [active]
1123863010991	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863010992	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863010993	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1123863010994	putative effector binding pocket; other site
1123863010995	putative dimerization interface [polypeptide binding]; other site
1123863010996	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1123863010997	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863010998	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863010999	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1123863011000	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1123863011001	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1123863011002	E3 interaction surface; other site
1123863011003	lipoyl attachment site [posttranslational modification]; other site
1123863011004	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1123863011005	E3 interaction surface; other site
1123863011006	lipoyl attachment site [posttranslational modification]; other site
1123863011007	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1123863011008	E3 interaction surface; other site
1123863011009	lipoyl attachment site [posttranslational modification]; other site
1123863011010	e3 binding domain; Region: E3_binding; pfam02817
1123863011011	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1123863011012	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1123863011013	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1123863011014	dimer interface [polypeptide binding]; other site
1123863011015	TPP-binding site [chemical binding]; other site
1123863011016	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1123863011017	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863011018	DNA-binding site [nucleotide binding]; DNA binding site
1123863011019	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1123863011020	aromatic amino acid transporter; Provisional; Region: PRK10238
1123863011021	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1123863011022	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011023	putative substrate translocation pore; other site
1123863011024	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1123863011025	active site
1123863011026	regulatory protein AmpE; Provisional; Region: PRK10987
1123863011027	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1123863011028	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1123863011029	amidase catalytic site [active]
1123863011030	substrate binding site [chemical binding]; other site
1123863011031	Zn binding residues [ion binding]; other site
1123863011032	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1123863011033	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1123863011034	dimerization interface [polypeptide binding]; other site
1123863011035	active site
1123863011036	hypothetical protein; Provisional; Region: PRK10436
1123863011037	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1123863011038	Walker A motif; other site
1123863011039	ATP binding site [chemical binding]; other site
1123863011040	Walker B motif; other site
1123863011041	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1123863011042	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1123863011043	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1123863011044	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1123863011045	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1123863011046	active site
1123863011047	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1123863011048	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1123863011049	CoA-binding site [chemical binding]; other site
1123863011050	ATP-binding [chemical binding]; other site
1123863011051	hypothetical protein; Provisional; Region: PRK05287
1123863011052	Domain of unknown function (DUF329); Region: DUF329; cl01144
1123863011053	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1123863011054	active site
1123863011055	8-oxo-dGMP binding site [chemical binding]; other site
1123863011056	nudix motif; other site
1123863011057	metal binding site [ion binding]; metal-binding site
1123863011058	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1123863011059	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1123863011060	SEC-C motif; Region: SEC-C; pfam02810
1123863011061	SecA regulator SecM; Provisional; Region: PRK02943
1123863011062	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1123863011063	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1123863011064	cell division protein FtsZ; Validated; Region: PRK09330
1123863011065	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1123863011066	nucleotide binding site [chemical binding]; other site
1123863011067	SulA interaction site; other site
1123863011068	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1123863011069	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1123863011070	Cell division protein FtsA; Region: FtsA; pfam14450
1123863011071	cell division protein FtsQ; Provisional; Region: PRK10775
1123863011072	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1123863011073	Cell division protein FtsQ; Region: FtsQ; pfam03799
1123863011074	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1123863011075	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1123863011076	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1123863011077	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1123863011078	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1123863011079	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1123863011080	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1123863011081	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1123863011082	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1123863011083	active site
1123863011084	homodimer interface [polypeptide binding]; other site
1123863011085	cell division protein FtsW; Provisional; Region: PRK10774
1123863011086	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1123863011087	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1123863011088	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1123863011089	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1123863011090	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1123863011091	Mg++ binding site [ion binding]; other site
1123863011092	putative catalytic motif [active]
1123863011093	putative substrate binding site [chemical binding]; other site
1123863011094	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1123863011095	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1123863011096	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1123863011097	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1123863011098	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1123863011099	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1123863011100	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1123863011101	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1123863011102	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1123863011103	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1123863011104	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1123863011105	cell division protein FtsL; Provisional; Region: PRK10772
1123863011106	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1123863011107	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1123863011108	cell division protein MraZ; Reviewed; Region: PRK00326
1123863011109	MraZ protein; Region: MraZ; pfam02381
1123863011110	MraZ protein; Region: MraZ; pfam02381
1123863011111	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1123863011112	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863011113	DNA binding site [nucleotide binding]
1123863011114	domain linker motif; other site
1123863011115	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1123863011116	dimerization interface [polypeptide binding]; other site
1123863011117	ligand binding site [chemical binding]; other site
1123863011118	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1123863011119	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1123863011120	putative valine binding site [chemical binding]; other site
1123863011121	dimer interface [polypeptide binding]; other site
1123863011122	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1123863011123	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1123863011124	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1123863011125	PYR/PP interface [polypeptide binding]; other site
1123863011126	dimer interface [polypeptide binding]; other site
1123863011127	TPP binding site [chemical binding]; other site
1123863011128	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1123863011129	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1123863011130	TPP-binding site [chemical binding]; other site
1123863011131	dimer interface [polypeptide binding]; other site
1123863011132	2-isopropylmalate synthase; Validated; Region: PRK00915
1123863011133	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1123863011134	active site
1123863011135	catalytic residues [active]
1123863011136	metal binding site [ion binding]; metal-binding site
1123863011137	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1123863011138	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1123863011139	tartrate dehydrogenase; Provisional; Region: PRK08194
1123863011140	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1123863011141	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1123863011142	substrate binding site [chemical binding]; other site
1123863011143	ligand binding site [chemical binding]; other site
1123863011144	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1123863011145	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1123863011146	substrate binding site [chemical binding]; other site
1123863011147	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1123863011148	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1123863011149	active site
1123863011150	FMN binding site [chemical binding]; other site
1123863011151	substrate binding site [chemical binding]; other site
1123863011152	putative catalytic residue [active]
1123863011153	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1123863011154	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1123863011155	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
1123863011156	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1123863011157	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1123863011158	shikimate binding site; other site
1123863011159	NAD(P) binding site [chemical binding]; other site
1123863011160	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011161	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863011162	putative substrate translocation pore; other site
1123863011163	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1123863011164	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1123863011165	active site
1123863011166	catalytic residue [active]
1123863011167	dimer interface [polypeptide binding]; other site
1123863011168	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863011169	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863011170	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
1123863011171	putative dimerization interface [polypeptide binding]; other site
1123863011172	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011173	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863011174	putative substrate translocation pore; other site
1123863011175	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011176	sugar efflux transporter; Region: 2A0120; TIGR00899
1123863011177	putative substrate translocation pore; other site
1123863011178	transcriptional regulator SgrR; Provisional; Region: PRK13626
1123863011179	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1123863011180	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1123863011181	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1123863011182	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1123863011183	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1123863011184	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863011185	dimer interface [polypeptide binding]; other site
1123863011186	conserved gate region; other site
1123863011187	putative PBP binding loops; other site
1123863011188	ABC-ATPase subunit interface; other site
1123863011189	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863011190	dimer interface [polypeptide binding]; other site
1123863011191	conserved gate region; other site
1123863011192	putative PBP binding loops; other site
1123863011193	ABC-ATPase subunit interface; other site
1123863011194	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1123863011195	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863011196	Walker A/P-loop; other site
1123863011197	ATP binding site [chemical binding]; other site
1123863011198	Q-loop/lid; other site
1123863011199	ABC transporter signature motif; other site
1123863011200	Walker B; other site
1123863011201	D-loop; other site
1123863011202	H-loop/switch region; other site
1123863011203	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1123863011204	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1123863011205	DNA polymerase II; Reviewed; Region: PRK05762
1123863011206	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1123863011207	active site
1123863011208	catalytic site [active]
1123863011209	substrate binding site [chemical binding]; other site
1123863011210	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1123863011211	active site
1123863011212	metal-binding site
1123863011213	ATP-dependent helicase HepA; Validated; Region: PRK04914
1123863011214	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863011215	ATP binding site [chemical binding]; other site
1123863011216	putative Mg++ binding site [ion binding]; other site
1123863011217	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863011218	nucleotide binding region [chemical binding]; other site
1123863011219	ATP-binding site [chemical binding]; other site
1123863011220	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1123863011221	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1123863011222	active site
1123863011223	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1123863011224	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1123863011225	putative metal binding site [ion binding]; other site
1123863011226	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1123863011227	HSP70 interaction site [polypeptide binding]; other site
1123863011228	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1123863011229	OstA-like protein; Region: OstA; pfam03968
1123863011230	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1123863011231	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1123863011232	SurA N-terminal domain; Region: SurA_N; pfam09312
1123863011233	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1123863011234	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1123863011235	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1123863011236	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1123863011237	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1123863011238	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863011239	S-adenosylmethionine binding site [chemical binding]; other site
1123863011240	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1123863011241	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
1123863011242	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1123863011243	active site
1123863011244	metal binding site [ion binding]; metal-binding site
1123863011245	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1123863011246	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1123863011247	folate binding site [chemical binding]; other site
1123863011248	NADP+ binding site [chemical binding]; other site
1123863011249	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1123863011250	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1123863011251	eyelet of channel; other site
1123863011252	trimer interface [polypeptide binding]; other site
1123863011253	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863011254	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863011255	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1123863011256	dimerization interface [polypeptide binding]; other site
1123863011257	putative effector binding pocket; other site
1123863011258	potential frameshift: common BLAST hit: gi|375260953|ref|YP_005020123.1| NAD-dependent epimerase/dehydratase
1123863011259	progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs; Region: 5beta-POR_like_SDR_a; cd08948
1123863011260	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1123863011261	NAD(P) binding site [chemical binding]; other site
1123863011262	active site
1123863011263	Mig-14; Region: Mig-14; pfam07395
1123863011264	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1123863011265	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1123863011266	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1123863011267	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1123863011268	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1123863011269	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1123863011270	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1123863011271	IMP binding site; other site
1123863011272	dimer interface [polypeptide binding]; other site
1123863011273	interdomain contacts; other site
1123863011274	partial ornithine binding site; other site
1123863011275	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1123863011276	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1123863011277	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1123863011278	catalytic site [active]
1123863011279	subunit interface [polypeptide binding]; other site
1123863011280	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1123863011281	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1123863011282	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1123863011283	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1123863011284	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1123863011285	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1123863011286	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1123863011287	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1123863011288	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1123863011289	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1123863011290	active site
1123863011291	HIGH motif; other site
1123863011292	nucleotide binding site [chemical binding]; other site
1123863011293	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1123863011294	active site
1123863011295	KMSKS motif; other site
1123863011296	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1123863011297	tRNA binding surface [nucleotide binding]; other site
1123863011298	anticodon binding site; other site
1123863011299	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1123863011300	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1123863011301	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1123863011302	active site
1123863011303	Riboflavin kinase; Region: Flavokinase; smart00904
1123863011304	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1123863011305	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1123863011306	chaperone protein DnaJ; Provisional; Region: PRK10767
1123863011307	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1123863011308	HSP70 interaction site [polypeptide binding]; other site
1123863011309	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1123863011310	substrate binding site [polypeptide binding]; other site
1123863011311	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1123863011312	Zn binding sites [ion binding]; other site
1123863011313	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1123863011314	dimer interface [polypeptide binding]; other site
1123863011315	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1123863011316	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1123863011317	nucleotide binding site [chemical binding]; other site
1123863011318	GPR1/FUN34/yaaH family; Region: Grp1_Fun34_YaaH; cl00685
1123863011319	metabolite-proton symporter; Region: 2A0106; TIGR00883
1123863011320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011321	putative substrate translocation pore; other site
1123863011322	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1123863011323	MPT binding site; other site
1123863011324	trimer interface [polypeptide binding]; other site
1123863011325	transaldolase-like protein; Provisional; Region: PTZ00411
1123863011326	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1123863011327	active site
1123863011328	dimer interface [polypeptide binding]; other site
1123863011329	catalytic residue [active]
1123863011330	hypothetical protein; Validated; Region: PRK02101
1123863011331	threonine synthase; Validated; Region: PRK09225
1123863011332	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1123863011333	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863011334	catalytic residue [active]
1123863011335	homoserine kinase; Provisional; Region: PRK01212
1123863011336	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1123863011337	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1123863011338	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1123863011339	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1123863011340	putative catalytic residues [active]
1123863011341	putative nucleotide binding site [chemical binding]; other site
1123863011342	putative aspartate binding site [chemical binding]; other site
1123863011343	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1123863011344	dimer interface [polypeptide binding]; other site
1123863011345	putative threonine allosteric regulatory site; other site
1123863011346	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1123863011347	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1123863011348	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1123863011349	putative RNA methyltransferase; Provisional; Region: PRK10433
1123863011350	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1123863011351	two-component response regulator; Provisional; Region: PRK11173
1123863011352	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863011353	active site
1123863011354	phosphorylation site [posttranslational modification]
1123863011355	intermolecular recognition site; other site
1123863011356	dimerization interface [polypeptide binding]; other site
1123863011357	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863011358	DNA binding site [nucleotide binding]
1123863011359	hypothetical protein; Provisional; Region: PRK10756
1123863011360	CreA protein; Region: CreA; pfam05981
1123863011361	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1123863011362	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863011363	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1123863011364	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1123863011365	catalytic core [active]
1123863011366	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1123863011367	Trp operon repressor; Provisional; Region: PRK01381
1123863011368	lytic murein transglycosylase; Provisional; Region: PRK11619
1123863011369	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1123863011370	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1123863011371	catalytic residue [active]
1123863011372	allophanate hydrolase; Provisional; Region: PRK08186
1123863011373	Amidase; Region: Amidase; cl11426
1123863011374	urea carboxylase; Region: urea_carbox; TIGR02712
1123863011375	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1123863011376	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1123863011377	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1123863011378	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1123863011379	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1123863011380	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1123863011381	carboxyltransferase (CT) interaction site; other site
1123863011382	biotinylation site [posttranslational modification]; other site
1123863011383	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1123863011384	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863011385	DNA-binding site [nucleotide binding]; DNA binding site
1123863011386	FCD domain; Region: FCD; pfam07729
1123863011387	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
1123863011388	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
1123863011389	putative ligand binding site [chemical binding]; other site
1123863011390	HEAT repeats; Region: HEAT_2; pfam13646
1123863011391	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1123863011392	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863011393	TM-ABC transporter signature motif; other site
1123863011394	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1123863011395	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1123863011396	TM-ABC transporter signature motif; other site
1123863011397	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
1123863011398	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1123863011399	Walker A/P-loop; other site
1123863011400	ATP binding site [chemical binding]; other site
1123863011401	Q-loop/lid; other site
1123863011402	ABC transporter signature motif; other site
1123863011403	Walker B; other site
1123863011404	D-loop; other site
1123863011405	H-loop/switch region; other site
1123863011406	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1123863011407	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1123863011408	Walker A/P-loop; other site
1123863011409	ATP binding site [chemical binding]; other site
1123863011410	Q-loop/lid; other site
1123863011411	ABC transporter signature motif; other site
1123863011412	Walker B; other site
1123863011413	D-loop; other site
1123863011414	H-loop/switch region; other site
1123863011415	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1123863011416	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863011417	N-terminal plug; other site
1123863011418	ligand-binding site [chemical binding]; other site
1123863011419	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1123863011420	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011421	putative substrate translocation pore; other site
1123863011422	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1123863011423	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
1123863011424	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1123863011425	IucA / IucC family; Region: IucA_IucC; pfam04183
1123863011426	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1123863011427	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
1123863011428	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863011429	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1123863011430	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863011431	catalytic residue [active]
1123863011432	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1123863011433	active site
1123863011434	catalytic residues [active]
1123863011435	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1123863011436	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011437	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863011438	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1123863011439	substrate binding site [chemical binding]; other site
1123863011440	dimer interface [polypeptide binding]; other site
1123863011441	ATP binding site [chemical binding]; other site
1123863011442	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1123863011443	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1123863011444	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863011445	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1123863011446	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863011447	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863011448	ABC transporter; Region: ABC_tran_2; pfam12848
1123863011449	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1123863011450	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863011451	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863011452	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1123863011453	putative effector binding pocket; other site
1123863011454	dimerization interface [polypeptide binding]; other site
1123863011455	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
1123863011456	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
1123863011457	putative NAD(P) binding site [chemical binding]; other site
1123863011458	dimer interface [polypeptide binding]; other site
1123863011459	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1123863011460	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863011461	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1123863011462	Fimbrial protein; Region: Fimbrial; cl01416
1123863011463	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1123863011464	PapC N-terminal domain; Region: PapC_N; pfam13954
1123863011465	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1123863011466	PapC C-terminal domain; Region: PapC_C; pfam13953
1123863011467	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1123863011468	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1123863011469	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1123863011470	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1123863011471	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1123863011472	DNA binding site [nucleotide binding]
1123863011473	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863011474	non-specific DNA binding site [nucleotide binding]; other site
1123863011475	salt bridge; other site
1123863011476	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1123863011477	sequence-specific DNA binding site [nucleotide binding]; other site
1123863011478	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1123863011479	active site
1123863011480	(T/H)XGH motif; other site
1123863011481	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1123863011482	DNA repair protein RadA; Region: sms; TIGR00416
1123863011483	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1123863011484	Walker A motif/ATP binding site; other site
1123863011485	ATP binding site [chemical binding]; other site
1123863011486	Walker B motif; other site
1123863011487	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1123863011488	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1123863011489	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863011490	motif II; other site
1123863011491	hypothetical protein; Provisional; Region: PRK11246
1123863011492	dUMP phosphatase; Provisional; Region: PRK09449
1123863011493	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863011494	motif II; other site
1123863011495	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1123863011496	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863011497	Coenzyme A binding pocket [chemical binding]; other site
1123863011498	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1123863011499	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1123863011500	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863011501	S-adenosylmethionine binding site [chemical binding]; other site
1123863011502	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1123863011503	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863011504	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863011505	metal binding site [ion binding]; metal-binding site
1123863011506	active site
1123863011507	I-site; other site
1123863011508	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1123863011509	putative deacylase active site [active]
1123863011510	putative sialic acid transporter; Region: 2A0112; TIGR00891
1123863011511	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011512	putative substrate translocation pore; other site
1123863011513	Inosine-uridine preferring nucleoside hydrolase; Region: IU_nuc_hydro; pfam01156
1123863011514	active site
1123863011515	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863011516	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863011517	DNA binding site [nucleotide binding]
1123863011518	domain linker motif; other site
1123863011519	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1123863011520	dimerization interface [polypeptide binding]; other site
1123863011521	ligand binding site [chemical binding]; other site
1123863011522	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011523	metabolite-proton symporter; Region: 2A0106; TIGR00883
1123863011524	putative substrate translocation pore; other site
1123863011525	Broad specificity phosphatase PhoE and related phosphatases [General function prediction only]; Region: phoE; COG0406
1123863011526	catalytic core [active]
1123863011527	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
1123863011528	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
1123863011529	Capsular polysaccharide synthesis protein; Region: Caps_synth; pfam05704
1123863011530	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
1123863011531	phosphoglycerol transferase I; Provisional; Region: PRK03776
1123863011532	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1123863011533	Protein of unknown function (DUF1640); Region: DUF1640; pfam07798
1123863011534	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1123863011535	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1123863011536	Domain of unknown function (DUF3315); Region: DUF3315; pfam11776
1123863011537	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1123863011538	Beta-lactamase; Region: Beta-lactamase; pfam00144
1123863011539	hypothetical protein; Provisional; Region: PRK10396
1123863011540	yecA family protein; Region: ygfB_yecA; TIGR02292
1123863011541	SEC-C motif; Region: SEC-C; pfam02810
1123863011542	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1123863011543	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863011544	DNA-binding site [nucleotide binding]; DNA binding site
1123863011545	FCD domain; Region: FCD; pfam07729
1123863011546	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011547	metabolite-proton symporter; Region: 2A0106; TIGR00883
1123863011548	putative substrate translocation pore; other site
1123863011549	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1123863011550	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1123863011551	putative NAD(P) binding site [chemical binding]; other site
1123863011552	catalytic Zn binding site [ion binding]; other site
1123863011553	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
1123863011554	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1123863011555	NADP binding site [chemical binding]; other site
1123863011556	homodimer interface [polypeptide binding]; other site
1123863011557	active site
1123863011558	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1123863011559	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1123863011560	metal binding site [ion binding]; metal-binding site
1123863011561	substrate binding pocket [chemical binding]; other site
1123863011562	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1123863011563	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1123863011564	Walker A/P-loop; other site
1123863011565	ATP binding site [chemical binding]; other site
1123863011566	Q-loop/lid; other site
1123863011567	ABC transporter signature motif; other site
1123863011568	Walker B; other site
1123863011569	D-loop; other site
1123863011570	H-loop/switch region; other site
1123863011571	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
1123863011572	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
1123863011573	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863011574	dimer interface [polypeptide binding]; other site
1123863011575	conserved gate region; other site
1123863011576	putative PBP binding loops; other site
1123863011577	ABC-ATPase subunit interface; other site
1123863011578	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863011579	dimer interface [polypeptide binding]; other site
1123863011580	conserved gate region; other site
1123863011581	putative PBP binding loops; other site
1123863011582	ABC-ATPase subunit interface; other site
1123863011583	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863011584	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1123863011585	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1123863011586	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1123863011587	NADP binding site [chemical binding]; other site
1123863011588	homodimer interface [polypeptide binding]; other site
1123863011589	active site
1123863011590	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1123863011591	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
1123863011592	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863011593	inhibitor-cofactor binding pocket; inhibition site
1123863011594	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863011595	catalytic residue [active]
1123863011596	ethanolamine permease; Region: 2A0305; TIGR00908
1123863011597	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1123863011598	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1123863011599	active site
1123863011600	substrate binding site [chemical binding]; other site
1123863011601	ATP binding site [chemical binding]; other site
1123863011602	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
1123863011603	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1123863011604	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863011605	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1123863011606	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1123863011607	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863011608	Coenzyme A binding pocket [chemical binding]; other site
1123863011609	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
1123863011610	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1123863011611	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1123863011612	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
1123863011613	Domain of unknown function (DUF3601); Region: DUF3601; pfam12208
1123863011614	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1123863011615	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1123863011616	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011617	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863011618	putative substrate translocation pore; other site
1123863011619	Domain of unknown function (DUF386); Region: DUF386; cl01047
1123863011620	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1123863011621	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1123863011622	inhibitor site; inhibition site
1123863011623	active site
1123863011624	dimer interface [polypeptide binding]; other site
1123863011625	catalytic residue [active]
1123863011626	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1123863011627	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1123863011628	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863011629	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1123863011630	substrate binding site [chemical binding]; other site
1123863011631	dimer interface [polypeptide binding]; other site
1123863011632	ATP binding site [chemical binding]; other site
1123863011633	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011634	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863011635	putative substrate translocation pore; other site
1123863011636	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1123863011637	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863011638	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863011639	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863011640	dimer interface [polypeptide binding]; other site
1123863011641	putative CheW interface [polypeptide binding]; other site
1123863011642	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1123863011643	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1123863011644	active site
1123863011645	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863011646	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863011647	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1123863011648	dimerization interface [polypeptide binding]; other site
1123863011649	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1123863011650	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1123863011651	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1123863011652	active site
1123863011653	AMP binding site [chemical binding]; other site
1123863011654	acyl-activating enzyme (AAE) consensus motif; other site
1123863011655	CoA binding site [chemical binding]; other site
1123863011656	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1123863011657	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863011658	catalytic residue [active]
1123863011659	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1123863011660	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
1123863011661	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863011662	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1123863011663	Phosphotransferase enzyme family; Region: APH; pfam01636
1123863011664	active site
1123863011665	ATP binding site [chemical binding]; other site
1123863011666	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1123863011667	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1123863011668	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1123863011669	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1123863011670	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1123863011671	ATP binding site [chemical binding]; other site
1123863011672	putative Mg++ binding site [ion binding]; other site
1123863011673	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1123863011674	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1123863011675	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1123863011676	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1123863011677	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1123863011678	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1123863011679	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1123863011680	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1123863011681	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1123863011682	ligand binding site [chemical binding]; other site
1123863011683	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1123863011684	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863011685	ATP binding site [chemical binding]; other site
1123863011686	putative Mg++ binding site [ion binding]; other site
1123863011687	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863011688	nucleotide binding region [chemical binding]; other site
1123863011689	ATP-binding site [chemical binding]; other site
1123863011690	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
1123863011691	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
1123863011692	hypothetical protein; Provisional; Region: PRK11667
1123863011693	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1123863011694	inner membrane protein; Provisional; Region: PRK10995
1123863011695	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1123863011696	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1123863011697	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
1123863011698	Zonular occludens toxin (Zot); Region: Zot; cl17485
1123863011699	HipA N-terminal domain; Region: Couple_hipA; cl11853
1123863011700	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1123863011701	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1123863011702	Predicted membrane protein [Function unknown]; Region: COG2733
1123863011703	BtpA family; Region: BtpA; cl00440
1123863011704	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863011705	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1123863011706	substrate binding site [chemical binding]; other site
1123863011707	dimer interface [polypeptide binding]; other site
1123863011708	ATP binding site [chemical binding]; other site
1123863011709	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1123863011710	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1123863011711	ligand binding site [chemical binding]; other site
1123863011712	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863011713	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863011714	DNA binding site [nucleotide binding]
1123863011715	domain linker motif; other site
1123863011716	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_11; cd06293
1123863011717	putative dimerization interface [polypeptide binding]; other site
1123863011718	putative ligand binding site [chemical binding]; other site
1123863011719	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1123863011720	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863011721	Walker A/P-loop; other site
1123863011722	ATP binding site [chemical binding]; other site
1123863011723	Q-loop/lid; other site
1123863011724	ABC transporter signature motif; other site
1123863011725	Walker B; other site
1123863011726	D-loop; other site
1123863011727	H-loop/switch region; other site
1123863011728	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863011729	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863011730	TM-ABC transporter signature motif; other site
1123863011731	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1123863011732	active site
1123863011733	substrate binding pocket [chemical binding]; other site
1123863011734	homodimer interaction site [polypeptide binding]; other site
1123863011735	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1123863011736	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1123863011737	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
1123863011738	metal binding site [ion binding]; metal-binding site
1123863011739	dimer interface [polypeptide binding]; other site
1123863011740	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1123863011741	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1123863011742	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1123863011743	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1123863011744	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1123863011745	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1123863011746	interface (dimer of trimers) [polypeptide binding]; other site
1123863011747	Substrate-binding/catalytic site; other site
1123863011748	Zn-binding sites [ion binding]; other site
1123863011749	DNA polymerase III subunit chi; Validated; Region: PRK05728
1123863011750	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1123863011751	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1123863011752	HIGH motif; other site
1123863011753	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1123863011754	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1123863011755	active site
1123863011756	KMSKS motif; other site
1123863011757	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1123863011758	tRNA binding surface [nucleotide binding]; other site
1123863011759	anticodon binding site; other site
1123863011760	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1123863011761	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863011762	Coenzyme A binding pocket [chemical binding]; other site
1123863011763	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1123863011764	active site
1123863011765	dinuclear metal binding site [ion binding]; other site
1123863011766	dimerization interface [polypeptide binding]; other site
1123863011767	RNase E inhibitor protein; Provisional; Region: PRK11191
1123863011768	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1123863011769	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1123863011770	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1123863011771	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1123863011772	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1123863011773	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1123863011774	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1123863011775	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1123863011776	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1123863011777	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1123863011778	homotrimer interaction site [polypeptide binding]; other site
1123863011779	putative active site [active]
1123863011780	Isochorismatase family; Region: Isochorismatase; pfam00857
1123863011781	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
1123863011782	catalytic triad [active]
1123863011783	conserved cis-peptide bond; other site
1123863011784	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
1123863011785	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1123863011786	conserved cys residue [active]
1123863011787	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863011788	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1123863011789	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863011790	putative substrate translocation pore; other site
1123863011791	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1123863011792	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1123863011793	putative acyl-acceptor binding pocket; other site
1123863011794	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1123863011795	acyl-activating enzyme (AAE) consensus motif; other site
1123863011796	putative AMP binding site [chemical binding]; other site
1123863011797	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1123863011798	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1123863011799	Protein export membrane protein; Region: SecD_SecF; cl14618
1123863011800	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1123863011801	Protein export membrane protein; Region: SecD_SecF; cl14618
1123863011802	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1123863011803	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863011804	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863011805	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1123863011806	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1123863011807	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1123863011808	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1123863011809	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1123863011810	molybdopterin cofactor binding site [chemical binding]; other site
1123863011811	substrate binding site [chemical binding]; other site
1123863011812	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1123863011813	molybdopterin cofactor binding site; other site
1123863011814	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1123863011815	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863011816	DNA binding site [nucleotide binding]
1123863011817	domain linker motif; other site
1123863011818	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1123863011819	dimerization interface (closed form) [polypeptide binding]; other site
1123863011820	ligand binding site [chemical binding]; other site
1123863011821	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
1123863011822	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
1123863011823	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
1123863011824	active site
1123863011825	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
1123863011826	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1123863011827	ATP cone domain; Region: ATP-cone; pfam03477
1123863011828	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1123863011829	effector binding site; other site
1123863011830	active site
1123863011831	Zn binding site [ion binding]; other site
1123863011832	glycine loop; other site
1123863011833	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
1123863011834	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863011835	FeS/SAM binding site; other site
1123863011836	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1123863011837	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1123863011838	NAD binding site [chemical binding]; other site
1123863011839	active site
1123863011840	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1123863011841	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1123863011842	proposed catalytic triad [active]
1123863011843	conserved cys residue [active]
1123863011844	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3787; cl17897
1123863011845	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1123863011846	GIY-YIG motif/motif A; other site
1123863011847	putative active site [active]
1123863011848	putative metal binding site [ion binding]; other site
1123863011849	putative acetyltransferase; Provisional; Region: PRK03624
1123863011850	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863011851	Coenzyme A binding pocket [chemical binding]; other site
1123863011852	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1123863011853	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1123863011854	Peptidase family U32; Region: Peptidase_U32; pfam01136
1123863011855	putative protease; Provisional; Region: PRK15447
1123863011856	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1123863011857	hypothetical protein; Provisional; Region: PRK10508
1123863011858	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
1123863011859	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1123863011860	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
1123863011861	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1123863011862	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1123863011863	ATP binding site [chemical binding]; other site
1123863011864	Mg++ binding site [ion binding]; other site
1123863011865	motif III; other site
1123863011866	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863011867	nucleotide binding region [chemical binding]; other site
1123863011868	ATP-binding site [chemical binding]; other site
1123863011869	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1123863011870	putative RNA binding site [nucleotide binding]; other site
1123863011871	lipoprotein NlpI; Provisional; Region: PRK11189
1123863011872	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1123863011873	binding surface
1123863011874	TPR motif; other site
1123863011875	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1123863011876	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1123863011877	RNase E interface [polypeptide binding]; other site
1123863011878	trimer interface [polypeptide binding]; other site
1123863011879	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1123863011880	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1123863011881	RNase E interface [polypeptide binding]; other site
1123863011882	trimer interface [polypeptide binding]; other site
1123863011883	active site
1123863011884	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1123863011885	putative nucleic acid binding region [nucleotide binding]; other site
1123863011886	G-X-X-G motif; other site
1123863011887	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1123863011888	RNA binding site [nucleotide binding]; other site
1123863011889	domain interface; other site
1123863011890	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1123863011891	16S/18S rRNA binding site [nucleotide binding]; other site
1123863011892	S13e-L30e interaction site [polypeptide binding]; other site
1123863011893	25S rRNA binding site [nucleotide binding]; other site
1123863011894	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1123863011895	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1123863011896	RNA binding site [nucleotide binding]; other site
1123863011897	active site
1123863011898	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1123863011899	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1123863011900	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1123863011901	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1123863011902	translation initiation factor IF-2; Region: IF-2; TIGR00487
1123863011903	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1123863011904	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1123863011905	G1 box; other site
1123863011906	putative GEF interaction site [polypeptide binding]; other site
1123863011907	GTP/Mg2+ binding site [chemical binding]; other site
1123863011908	Switch I region; other site
1123863011909	G2 box; other site
1123863011910	G3 box; other site
1123863011911	Switch II region; other site
1123863011912	G4 box; other site
1123863011913	G5 box; other site
1123863011914	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1123863011915	Translation-initiation factor 2; Region: IF-2; pfam11987
1123863011916	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1123863011917	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1123863011918	NusA N-terminal domain; Region: NusA_N; pfam08529
1123863011919	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1123863011920	RNA binding site [nucleotide binding]; other site
1123863011921	homodimer interface [polypeptide binding]; other site
1123863011922	NusA-like KH domain; Region: KH_5; pfam13184
1123863011923	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1123863011924	G-X-X-G motif; other site
1123863011925	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1123863011926	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1123863011927	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1123863011928	Sm and related proteins; Region: Sm_like; cl00259
1123863011929	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1123863011930	putative oligomer interface [polypeptide binding]; other site
1123863011931	putative RNA binding site [nucleotide binding]; other site
1123863011932	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1123863011933	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1123863011934	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1123863011935	active site
1123863011936	substrate binding site [chemical binding]; other site
1123863011937	metal binding site [ion binding]; metal-binding site
1123863011938	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1123863011939	dihydropteroate synthase; Region: DHPS; TIGR01496
1123863011940	substrate binding pocket [chemical binding]; other site
1123863011941	dimer interface [polypeptide binding]; other site
1123863011942	inhibitor binding site; inhibition site
1123863011943	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1123863011944	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1123863011945	Walker A motif; other site
1123863011946	ATP binding site [chemical binding]; other site
1123863011947	Walker B motif; other site
1123863011948	arginine finger; other site
1123863011949	Peptidase family M41; Region: Peptidase_M41; pfam01434
1123863011950	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1123863011951	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863011952	S-adenosylmethionine binding site [chemical binding]; other site
1123863011953	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; cl00663
1123863011954	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1123863011955	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1123863011956	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1123863011957	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1123863011958	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1123863011959	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1123863011960	CoenzymeA binding site [chemical binding]; other site
1123863011961	subunit interaction site [polypeptide binding]; other site
1123863011962	PHB binding site; other site
1123863011963	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1123863011964	GTP1/OBG; Region: GTP1_OBG; pfam01018
1123863011965	Obg GTPase; Region: Obg; cd01898
1123863011966	G1 box; other site
1123863011967	GTP/Mg2+ binding site [chemical binding]; other site
1123863011968	Switch I region; other site
1123863011969	G2 box; other site
1123863011970	G3 box; other site
1123863011971	Switch II region; other site
1123863011972	G4 box; other site
1123863011973	G5 box; other site
1123863011974	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1123863011975	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1123863011976	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1123863011977	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1123863011978	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1123863011979	substrate binding pocket [chemical binding]; other site
1123863011980	chain length determination region; other site
1123863011981	substrate-Mg2+ binding site; other site
1123863011982	catalytic residues [active]
1123863011983	aspartate-rich region 1; other site
1123863011984	active site lid residues [active]
1123863011985	aspartate-rich region 2; other site
1123863011986	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
1123863011987	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1123863011988	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1123863011989	hinge; other site
1123863011990	active site
1123863011991	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1123863011992	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1123863011993	anti sigma factor interaction site; other site
1123863011994	regulatory phosphorylation site [posttranslational modification]; other site
1123863011995	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1123863011996	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1123863011997	mce related protein; Region: MCE; pfam02470
1123863011998	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1123863011999	conserved hypothetical integral membrane protein; Region: TIGR00056
1123863012000	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1123863012001	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1123863012002	Walker A/P-loop; other site
1123863012003	ATP binding site [chemical binding]; other site
1123863012004	Q-loop/lid; other site
1123863012005	ABC transporter signature motif; other site
1123863012006	Walker B; other site
1123863012007	D-loop; other site
1123863012008	H-loop/switch region; other site
1123863012009	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1123863012010	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1123863012011	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1123863012012	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1123863012013	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1123863012014	putative active site [active]
1123863012015	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1123863012016	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1123863012017	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1123863012018	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1123863012019	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1123863012020	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1123863012021	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1123863012022	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1123863012023	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1123863012024	Walker A/P-loop; other site
1123863012025	ATP binding site [chemical binding]; other site
1123863012026	Q-loop/lid; other site
1123863012027	ABC transporter signature motif; other site
1123863012028	Walker B; other site
1123863012029	D-loop; other site
1123863012030	H-loop/switch region; other site
1123863012031	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1123863012032	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1123863012033	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1123863012034	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1123863012035	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1123863012036	30S subunit binding site; other site
1123863012037	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863012038	active site
1123863012039	phosphorylation site [posttranslational modification]
1123863012040	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
1123863012041	AAA domain; Region: AAA_18; pfam13238
1123863012042	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1123863012043	dimerization domain swap beta strand [polypeptide binding]; other site
1123863012044	regulatory protein interface [polypeptide binding]; other site
1123863012045	active site
1123863012046	regulatory phosphorylation site [posttranslational modification]; other site
1123863012047	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1123863012048	Transglycosylase; Region: Transgly; cl17702
1123863012049	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1123863012050	Remorin, C-terminal region; Region: Remorin_C; pfam03763
1123863012051	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863012052	putative active site [active]
1123863012053	heme pocket [chemical binding]; other site
1123863012054	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863012055	dimer interface [polypeptide binding]; other site
1123863012056	phosphorylation site [posttranslational modification]
1123863012057	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863012058	ATP binding site [chemical binding]; other site
1123863012059	Mg2+ binding site [ion binding]; other site
1123863012060	G-X-G motif; other site
1123863012061	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863012062	active site
1123863012063	phosphorylation site [posttranslational modification]
1123863012064	intermolecular recognition site; other site
1123863012065	dimerization interface [polypeptide binding]; other site
1123863012066	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1123863012067	putative binding surface; other site
1123863012068	active site
1123863012069	Glutamate synthase domain 1 [Amino acid transport and metabolism]; Region: GltB; COG0067
1123863012070	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1123863012071	active site
1123863012072	dimer interface [polypeptide binding]; other site
1123863012073	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1123863012074	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1123863012075	active site
1123863012076	FMN binding site [chemical binding]; other site
1123863012077	substrate binding site [chemical binding]; other site
1123863012078	3Fe-4S cluster binding site [ion binding]; other site
1123863012079	GXGXG domain. This domain of unknown function is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS),  in subunit C of tungsten formylmethanofuran dehydrogenase (FwdC) and in subunit C of molybdenum formylmethanofuran...; Region: GXGXG; cl00239
1123863012080	domain_subunit interface; other site
1123863012081	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
1123863012082	Flavodoxin; Region: Flavodoxin_1; pfam00258
1123863012083	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1123863012084	FAD binding pocket [chemical binding]; other site
1123863012085	FAD binding motif [chemical binding]; other site
1123863012086	catalytic residues [active]
1123863012087	NAD binding pocket [chemical binding]; other site
1123863012088	phosphate binding motif [ion binding]; other site
1123863012089	beta-alpha-beta structure motif; other site
1123863012090	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1123863012091	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1123863012092	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1123863012093	C-terminal domain interface [polypeptide binding]; other site
1123863012094	putative GSH binding site (G-site) [chemical binding]; other site
1123863012095	dimer interface [polypeptide binding]; other site
1123863012096	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1123863012097	dimer interface [polypeptide binding]; other site
1123863012098	N-terminal domain interface [polypeptide binding]; other site
1123863012099	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1123863012100	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1123863012101	23S rRNA interface [nucleotide binding]; other site
1123863012102	L3 interface [polypeptide binding]; other site
1123863012103	Predicted ATPase [General function prediction only]; Region: COG1485
1123863012104	hypothetical protein; Provisional; Region: PRK11677
1123863012105	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1123863012106	serine endoprotease; Provisional; Region: PRK10139
1123863012107	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1123863012108	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1123863012109	protein binding site [polypeptide binding]; other site
1123863012110	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1123863012111	protein binding site [polypeptide binding]; other site
1123863012112	serine endoprotease; Provisional; Region: PRK10898
1123863012113	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1123863012114	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1123863012115	protein binding site [polypeptide binding]; other site
1123863012116	poxB regulator PoxA; Provisional; Region: PRK09350
1123863012117	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1123863012118	motif 1; other site
1123863012119	dimer interface [polypeptide binding]; other site
1123863012120	active site
1123863012121	motif 2; other site
1123863012122	motif 3; other site
1123863012123	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1123863012124	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1123863012125	Predicted small secreted protein [Function unknown]; Region: COG5510
1123863012126	Entericidin EcnA/B family; Region: Entericidin; pfam08085
1123863012127	elongation factor P; Validated; Region: PRK00529
1123863012128	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1123863012129	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1123863012130	RNA binding site [nucleotide binding]; other site
1123863012131	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1123863012132	RNA binding site [nucleotide binding]; other site
1123863012133	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1123863012134	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1123863012135	FeS/SAM binding site; other site
1123863012136	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1123863012137	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1123863012138	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1123863012139	ring oligomerisation interface [polypeptide binding]; other site
1123863012140	ATP/Mg binding site [chemical binding]; other site
1123863012141	stacking interactions; other site
1123863012142	hinge regions; other site
1123863012143	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1123863012144	oligomerisation interface [polypeptide binding]; other site
1123863012145	mobile loop; other site
1123863012146	roof hairpin; other site
1123863012147	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1123863012148	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1123863012149	Aspartase; Region: Aspartase; cd01357
1123863012150	active sites [active]
1123863012151	tetramer interface [polypeptide binding]; other site
1123863012152	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1123863012153	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1123863012154	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1123863012155	potential protein location (hypothetical protein) that overlaps protein (divalent-cation tolerance protein CutA)
1123863012156	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1123863012157	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1123863012158	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1123863012159	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1123863012160	DsbD alpha interface [polypeptide binding]; other site
1123863012161	catalytic residues [active]
1123863012162	putative transcriptional regulator; Provisional; Region: PRK11640
1123863012163	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1123863012164	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1123863012165	active site
1123863012166	catalytic residues [active]
1123863012167	DNA binding site [nucleotide binding]
1123863012168	Int/Topo IB signature motif; other site
1123863012169	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
1123863012170	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
1123863012171	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1123863012172	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1123863012173	Predicted Zn-dependent protease (DUF2268); Region: DUF2268; cl02316
1123863012174	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863012175	Coenzyme A binding pocket [chemical binding]; other site
1123863012176	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1123863012177	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1123863012178	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1123863012179	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863012180	Coenzyme A binding pocket [chemical binding]; other site
1123863012181	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1123863012182	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863012183	non-specific DNA binding site [nucleotide binding]; other site
1123863012184	salt bridge; other site
1123863012185	sequence-specific DNA binding site [nucleotide binding]; other site
1123863012186	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
1123863012187	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863012188	dimerization interface [polypeptide binding]; other site
1123863012189	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863012190	dimer interface [polypeptide binding]; other site
1123863012191	putative CheW interface [polypeptide binding]; other site
1123863012192	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1123863012193	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1123863012194	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1123863012195	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1123863012196	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863012197	Coenzyme A binding pocket [chemical binding]; other site
1123863012198	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1123863012199	active site
1123863012200	DNA binding site [nucleotide binding]
1123863012201	Int/Topo IB signature motif; other site
1123863012202	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863012203	HAMP domain; Region: HAMP; pfam00672
1123863012204	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863012205	dimer interface [polypeptide binding]; other site
1123863012206	putative CheW interface [polypeptide binding]; other site
1123863012207	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1123863012208	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1123863012209	inhibitor site; inhibition site
1123863012210	active site
1123863012211	dimer interface [polypeptide binding]; other site
1123863012212	catalytic residue [active]
1123863012213	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1123863012214	B3/4 domain; Region: B3_4; pfam03483
1123863012215	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1123863012216	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863012217	non-specific DNA binding site [nucleotide binding]; other site
1123863012218	salt bridge; other site
1123863012219	sequence-specific DNA binding site [nucleotide binding]; other site
1123863012220	Cupin domain; Region: Cupin_2; pfam07883
1123863012221	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; pfam06440
1123863012222	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1123863012223	DNA binding site [nucleotide binding]
1123863012224	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1123863012225	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
1123863012226	structural tetrad; other site
1123863012227	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
1123863012228	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes sulfite sensitivity protein (sulfite efflux pump; SSU1); Region: TDT_SSU1; cd09318
1123863012229	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1123863012230	gating phenylalanine in ion channel; other site
1123863012231	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
1123863012232	ligand binding site [chemical binding]; other site
1123863012233	active site
1123863012234	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
1123863012235	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1123863012236	DHHA2 domain; Region: DHHA2; pfam02833
1123863012237	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1123863012238	Ligand Binding Site [chemical binding]; other site
1123863012239	enolase; Provisional; Region: eno; PRK00077
1123863012240	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1123863012241	dimer interface [polypeptide binding]; other site
1123863012242	metal binding site [ion binding]; metal-binding site
1123863012243	substrate binding pocket [chemical binding]; other site
1123863012244	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1123863012245	catalytic core [active]
1123863012246	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1123863012247	chromosome condensation membrane protein; Provisional; Region: PRK14196
1123863012248	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1123863012249	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863012250	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1123863012251	active site
1123863012252	catalytic residues [active]
1123863012253	DNA binding site [nucleotide binding]
1123863012254	Int/Topo IB signature motif; other site
1123863012255	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1123863012256	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
1123863012257	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1123863012258	active site
1123863012259	catalytic residues [active]
1123863012260	DNA binding site [nucleotide binding]
1123863012261	Int/Topo IB signature motif; other site
1123863012262	Y-family of DNA polymerases; Region: PolY; cl12025
1123863012263	active site
1123863012264	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1123863012265	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1123863012266	Catalytic site [active]
1123863012267	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1123863012268	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
1123863012269	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1123863012270	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1123863012271	Protein of unknown function (DUF3085); Region: DUF3085; pfam11284
1123863012272	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1123863012273	Integrase; Region: Integrase_1; pfam12835
1123863012274	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
1123863012275	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
1123863012276	PhoU domain; Region: PhoU; pfam01895
1123863012277	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
1123863012278	Protein of unknown function (DUF1525); Region: DUF1525; pfam07511
1123863012279	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1123863012280	ATP binding site [chemical binding]; other site
1123863012281	Mg2+ binding site [ion binding]; other site
1123863012282	G-X-G motif; other site
1123863012283	PerC transcriptional activator; Region: PerC; pfam06069
1123863012284	Protein of unknown function DUF262; Region: DUF262; pfam03235
1123863012285	conjugative transfer ATPase, PFL_4706 family; Region: traC_PFL_4706; TIGR03744
1123863012286	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
1123863012287	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
1123863012288	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
1123863012289	Protein of unknown function (DUF3438); Region: DUF3438; pfam11920
1123863012290	integrating conjugative element protein, PFL_4703 family; Region: conj_TIGR03746
1123863012291	conjugative transfer region protein, TIGR03750 family; Region: conj_TIGR03750
1123863012292	Protein of unknown function (DUF2976); Region: DUF2976; cl12739
1123863012293	Protein of unknown function (DUF3262); Region: DUF3262; cl13160
1123863012294	integrative conjugative element protein, RAQPRD family; Region: ICE_RAQPRD; TIGR01690
1123863012295	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
1123863012296	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1123863012297	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1123863012298	Predicted ATPase [General function prediction only]; Region: COG5293
1123863012299	Uncharacterized protein conserved in bacteria (DUF2326); Region: DUF2326; pfam10088
1123863012300	Helix-turn-helix domain; Region: HTH_37; pfam13744
1123863012301	integrating conjugative element membrane protein, PFL_4697 family; Region: conj_TIGR03747
1123863012302	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
1123863012303	conjugative coupling factor TraD, TOL family; Region: conj_TOL_TraD; TIGR03754
1123863012304	Restriction endonuclease; Region: Mrr_cat; pfam04471
1123863012305	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
1123863012306	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
1123863012307	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
1123863012308	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1123863012309	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1123863012310	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1123863012311	catalytic residue [active]
1123863012312	PilS N terminal; Region: PilS; pfam08805
1123863012313	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1123863012314	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1123863012315	Type II/IV secretion system protein; Region: T2SE; pfam00437
1123863012316	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1123863012317	Walker A motif; other site
1123863012318	ATP binding site [chemical binding]; other site
1123863012319	Walker B motif; other site
1123863012320	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
1123863012321	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
1123863012322	type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520
1123863012323	Secretin N-terminal domain; Region: Secretin_N_2; pfam07655
1123863012324	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1123863012325	PilM; Region: PilM; pfam07419
1123863012326	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
1123863012327	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
1123863012328	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1123863012329	Domain of unknown function DUF29; Region: DUF29; pfam01724
1123863012330	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1123863012331	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1123863012332	dimer interface [polypeptide binding]; other site
1123863012333	ssDNA binding site [nucleotide binding]; other site
1123863012334	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1123863012335	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
1123863012336	DNA topoisomerase III; Provisional; Region: PRK07726
1123863012337	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1123863012338	active site
1123863012339	putative interdomain interaction site [polypeptide binding]; other site
1123863012340	putative metal-binding site [ion binding]; other site
1123863012341	putative nucleotide binding site [chemical binding]; other site
1123863012342	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1123863012343	domain I; other site
1123863012344	DNA binding groove [nucleotide binding]
1123863012345	phosphate binding site [ion binding]; other site
1123863012346	domain II; other site
1123863012347	domain III; other site
1123863012348	nucleotide binding site [chemical binding]; other site
1123863012349	catalytic site [active]
1123863012350	domain IV; other site
1123863012351	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1123863012352	Domain of unknown function (DUF1845); Region: DUF1845; pfam08900
1123863012353	Helix-turn-helix domain; Region: HTH_36; pfam13730
1123863012354	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
1123863012355	Protein of unknown function (DUF2786); Region: DUF2786; pfam10979
1123863012356	integrating conjugative element, PFGI_1 class, ParB family protein; Region: ICE_PFGI_1_parB; TIGR03764
1123863012357	ParB-like nuclease domain; Region: ParBc; pfam02195
1123863012358	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1123863012359	replicative DNA helicase; Region: DnaB; TIGR00665
1123863012360	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1123863012361	Walker A motif; other site
1123863012362	ATP binding site [chemical binding]; other site
1123863012363	Walker B motif; other site
1123863012364	DNA binding loops [nucleotide binding]
1123863012365	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1123863012366	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1123863012367	P-loop; other site
1123863012368	Magnesium ion binding site [ion binding]; other site
1123863012369	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1123863012370	Transposase; Region: HTH_Tnp_1; cl17663
1123863012371	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1123863012372	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1123863012373	active site
1123863012374	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1123863012375	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1123863012376	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1123863012377	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1123863012378	active site
1123863012379	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1123863012380	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1123863012381	G1 box; other site
1123863012382	GTP/Mg2+ binding site [chemical binding]; other site
1123863012383	Switch I region; other site
1123863012384	G2 box; other site
1123863012385	G3 box; other site
1123863012386	Switch II region; other site
1123863012387	G4 box; other site
1123863012388	G5 box; other site
1123863012389	Nucleoside recognition; Region: Gate; pfam07670
1123863012390	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1123863012391	Nucleoside recognition; Region: Gate; pfam07670
1123863012392	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1123863012393	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1123863012394	DNA-binding site [nucleotide binding]; DNA binding site
1123863012395	RNA-binding motif; other site
1123863012396	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1123863012397	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1123863012398	dimer interface [polypeptide binding]; other site
1123863012399	ligand binding site [chemical binding]; other site
1123863012400	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863012401	dimerization interface [polypeptide binding]; other site
1123863012402	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863012403	dimer interface [polypeptide binding]; other site
1123863012404	putative CheW interface [polypeptide binding]; other site
1123863012405	YCII-related domain; Region: YCII; cl00999
1123863012406	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1123863012407	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1123863012408	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1123863012409	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
1123863012410	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1123863012411	conserved cys residue [active]
1123863012412	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863012413	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495
1123863012414	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1123863012415	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1123863012416	active site
1123863012417	catalytic tetrad [active]
1123863012418	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
1123863012419	Cupin domain; Region: Cupin_2; cl17218
1123863012420	AAA domain; Region: AAA_17; pfam13207
1123863012421	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1123863012422	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863012423	Coenzyme A binding pocket [chemical binding]; other site
1123863012424	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1123863012425	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1123863012426	Bacterial transcriptional regulator; Region: IclR; pfam01614
1123863012427	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1123863012428	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1123863012429	Walker A/P-loop; other site
1123863012430	ATP binding site [chemical binding]; other site
1123863012431	Q-loop/lid; other site
1123863012432	ABC transporter signature motif; other site
1123863012433	Walker B; other site
1123863012434	D-loop; other site
1123863012435	H-loop/switch region; other site
1123863012436	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1123863012437	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1123863012438	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1123863012439	TM-ABC transporter signature motif; other site
1123863012440	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_6; cd06315
1123863012441	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1123863012442	putative ligand binding site [chemical binding]; other site
1123863012443	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1123863012444	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1123863012445	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1123863012446	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863012447	D-galactonate transporter; Region: 2A0114; TIGR00893
1123863012448	putative substrate translocation pore; other site
1123863012449	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1123863012450	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1123863012451	putative N- and C-terminal domain interface [polypeptide binding]; other site
1123863012452	putative active site [active]
1123863012453	MgATP binding site [chemical binding]; other site
1123863012454	catalytic site [active]
1123863012455	metal binding site [ion binding]; metal-binding site
1123863012456	putative xylulose binding site [chemical binding]; other site
1123863012457	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1123863012458	active site
1123863012459	magnesium binding site [ion binding]; other site
1123863012460	dimer interface [polypeptide binding]; other site
1123863012461	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1123863012462	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1123863012463	AP (apurinic/apyrimidinic) site pocket; other site
1123863012464	DNA interaction; other site
1123863012465	Metal-binding active site; metal-binding site
1123863012466	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1123863012467	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1123863012468	intersubunit interface [polypeptide binding]; other site
1123863012469	active site
1123863012470	Zn2+ binding site [ion binding]; other site
1123863012471	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
1123863012472	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1123863012473	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1123863012474	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863012475	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863012476	dimer interface [polypeptide binding]; other site
1123863012477	putative CheW interface [polypeptide binding]; other site
1123863012478	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1123863012479	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863012480	N-terminal plug; other site
1123863012481	ligand-binding site [chemical binding]; other site
1123863012482	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
1123863012483	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863012484	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1123863012485	IucA / IucC family; Region: IucA_IucC; pfam04183
1123863012486	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1123863012487	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1123863012488	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
1123863012489	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1123863012490	IucA / IucC family; Region: IucA_IucC; pfam04183
1123863012491	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1123863012492	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863012493	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863012494	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1123863012495	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1123863012496	FAD binding pocket [chemical binding]; other site
1123863012497	FAD binding motif [chemical binding]; other site
1123863012498	phosphate binding motif [ion binding]; other site
1123863012499	NAD binding pocket [chemical binding]; other site
1123863012500	Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; pfam04828
1123863012501	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863012502	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863012503	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863012504	dimerization interface [polypeptide binding]; other site
1123863012505	Phenolic acid decarboxylase (PAD); Region: PA_decarbox; cl01382
1123863012506	DsrE/DsrF-like family; Region: DrsE; cl00672
1123863012507	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1123863012508	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1123863012509	Putative phosphatase (DUF442); Region: DUF442; cl17385
1123863012510	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1123863012511	Predicted transporter component [General function prediction only]; Region: COG2391
1123863012512	Predicted transporter component [General function prediction only]; Region: COG2391
1123863012513	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1123863012514	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1123863012515	dimerization domain [polypeptide binding]; other site
1123863012516	dimer interface [polypeptide binding]; other site
1123863012517	catalytic residues [active]
1123863012518	D-fructose-responsive transcription factor; Region: fruct_sucro_rep; TIGR02417
1123863012519	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863012520	DNA binding site [nucleotide binding]
1123863012521	domain linker motif; other site
1123863012522	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1123863012523	dimerization interface [polypeptide binding]; other site
1123863012524	ligand binding site [chemical binding]; other site
1123863012525	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1123863012526	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1123863012527	substrate binding [chemical binding]; other site
1123863012528	active site
1123863012529	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1123863012530	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1123863012531	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1123863012532	active site turn [active]
1123863012533	phosphorylation site [posttranslational modification]
1123863012534	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1123863012535	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1123863012536	trimer interface; other site
1123863012537	sugar binding site [chemical binding]; other site
1123863012538	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
1123863012539	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863012540	putative substrate translocation pore; other site
1123863012541	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
1123863012542	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1123863012543	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1123863012544	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1123863012545	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1123863012546	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863012547	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1123863012548	putative substrate binding site [chemical binding]; other site
1123863012549	putative ATP binding site [chemical binding]; other site
1123863012550	putative S-transferase; Provisional; Region: PRK11752
1123863012551	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1123863012552	C-terminal domain interface [polypeptide binding]; other site
1123863012553	GSH binding site (G-site) [chemical binding]; other site
1123863012554	dimer interface [polypeptide binding]; other site
1123863012555	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1123863012556	N-terminal domain interface [polypeptide binding]; other site
1123863012557	dimer interface [polypeptide binding]; other site
1123863012558	substrate binding pocket (H-site) [chemical binding]; other site
1123863012559	Protein of unknown function (DUF1330); Region: DUF1330; pfam07045
1123863012560	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863012561	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863012562	dimer interface [polypeptide binding]; other site
1123863012563	putative CheW interface [polypeptide binding]; other site
1123863012564	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863012565	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863012566	dimerization interface [polypeptide binding]; other site
1123863012567	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1123863012568	tartrate dehydrogenase; Region: TTC; TIGR02089
1123863012569	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1123863012570	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1123863012571	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863012572	dimer interface [polypeptide binding]; other site
1123863012573	conserved gate region; other site
1123863012574	putative PBP binding loops; other site
1123863012575	ABC-ATPase subunit interface; other site
1123863012576	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863012577	dimer interface [polypeptide binding]; other site
1123863012578	conserved gate region; other site
1123863012579	putative PBP binding loops; other site
1123863012580	ABC-ATPase subunit interface; other site
1123863012581	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1123863012582	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1123863012583	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1123863012584	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1123863012585	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863012586	Walker A/P-loop; other site
1123863012587	ATP binding site [chemical binding]; other site
1123863012588	Q-loop/lid; other site
1123863012589	ABC transporter signature motif; other site
1123863012590	Walker B; other site
1123863012591	D-loop; other site
1123863012592	H-loop/switch region; other site
1123863012593	TOBE domain; Region: TOBE_2; pfam08402
1123863012594	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1123863012595	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1123863012596	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1123863012597	Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism]; Region: COG2971
1123863012598	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1123863012599	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863012600	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
1123863012601	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1123863012602	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1123863012603	Trp docking motif [polypeptide binding]; other site
1123863012604	putative active site [active]
1123863012605	drug efflux system protein MdtG; Provisional; Region: PRK09874
1123863012606	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863012607	putative substrate translocation pore; other site
1123863012608	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863012609	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863012610	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1123863012611	putative effector binding pocket; other site
1123863012612	dimerization interface [polypeptide binding]; other site
1123863012613	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1123863012614	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863012615	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863012616	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1123863012617	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863012618	active site
1123863012619	phosphorylation site [posttranslational modification]
1123863012620	intermolecular recognition site; other site
1123863012621	dimerization interface [polypeptide binding]; other site
1123863012622	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863012623	DNA binding site [nucleotide binding]
1123863012624	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1123863012625	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863012626	dimer interface [polypeptide binding]; other site
1123863012627	phosphorylation site [posttranslational modification]
1123863012628	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863012629	ATP binding site [chemical binding]; other site
1123863012630	Mg2+ binding site [ion binding]; other site
1123863012631	G-X-G motif; other site
1123863012632	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1123863012633	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1123863012634	dimer interface [polypeptide binding]; other site
1123863012635	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863012636	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
1123863012637	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863012638	dimerization interface [polypeptide binding]; other site
1123863012639	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863012640	dimer interface [polypeptide binding]; other site
1123863012641	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1123863012642	putative CheW interface [polypeptide binding]; other site
1123863012643	benzoate transport; Region: 2A0115; TIGR00895
1123863012644	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863012645	putative substrate translocation pore; other site
1123863012646	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863012647	Cytochrome c; Region: Cytochrom_C; pfam00034
1123863012648	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1123863012649	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
1123863012650	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1123863012651	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1123863012652	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1123863012653	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1123863012654	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
1123863012655	microcin B17 transporter; Reviewed; Region: PRK11098
1123863012656	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1123863012657	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863012658	putative substrate translocation pore; other site
1123863012659	Cupin; Region: Cupin_6; pfam12852
1123863012660	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863012661	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1123863012662	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863012663	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863012664	PAS domain; Region: PAS_9; pfam13426
1123863012665	putative active site [active]
1123863012666	heme pocket [chemical binding]; other site
1123863012667	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863012668	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863012669	dimer interface [polypeptide binding]; other site
1123863012670	putative CheW interface [polypeptide binding]; other site
1123863012671	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1123863012672	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1123863012673	active site turn [active]
1123863012674	phosphorylation site [posttranslational modification]
1123863012675	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1123863012676	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1123863012677	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1123863012678	putative active site [active]
1123863012679	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1123863012680	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1123863012681	acetyl-CoA synthetase; Provisional; Region: PRK00174
1123863012682	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1123863012683	active site
1123863012684	CoA binding site [chemical binding]; other site
1123863012685	acyl-activating enzyme (AAE) consensus motif; other site
1123863012686	AMP binding site [chemical binding]; other site
1123863012687	acetate binding site [chemical binding]; other site
1123863012688	Predicted membrane protein [Function unknown]; Region: COG3162
1123863012689	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1123863012690	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1123863012691	Na binding site [ion binding]; other site
1123863012692	YfaZ precursor; Region: YfaZ; pfam07437
1123863012693	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1123863012694	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1123863012695	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1123863012696	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863012697	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863012698	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1123863012699	putative dimerization interface [polypeptide binding]; other site
1123863012700	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1123863012701	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1123863012702	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1123863012703	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1123863012704	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1123863012705	putative C-terminal domain interface [polypeptide binding]; other site
1123863012706	putative GSH binding site (G-site) [chemical binding]; other site
1123863012707	putative dimer interface [polypeptide binding]; other site
1123863012708	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1123863012709	putative N-terminal domain interface [polypeptide binding]; other site
1123863012710	putative dimer interface [polypeptide binding]; other site
1123863012711	putative substrate binding pocket (H-site) [chemical binding]; other site
1123863012712	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1123863012713	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1123863012714	DNA binding residues [nucleotide binding]
1123863012715	dimer interface [polypeptide binding]; other site
1123863012716	[2Fe-2S] cluster binding site [ion binding]; other site
1123863012717	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1123863012718	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863012719	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1123863012720	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1123863012721	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1123863012722	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1123863012723	DNA-binding interface [nucleotide binding]; DNA binding site
1123863012724	Winged helix-turn helix; Region: HTH_29; pfam13551
1123863012725	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1123863012726	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1123863012727	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863012728	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1123863012729	catalytic triad [active]
1123863012730	conserved cis-peptide bond; other site
1123863012731	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
1123863012732	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1123863012733	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1123863012734	dimer interface [polypeptide binding]; other site
1123863012735	ssDNA binding site [nucleotide binding]; other site
1123863012736	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1123863012737	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1123863012738	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1123863012739	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1123863012740	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1123863012741	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1123863012742	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1123863012743	putative NAD(P) binding site [chemical binding]; other site
1123863012744	putative substrate binding site [chemical binding]; other site
1123863012745	catalytic Zn binding site [ion binding]; other site
1123863012746	structural Zn binding site [ion binding]; other site
1123863012747	dimer interface [polypeptide binding]; other site
1123863012748	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1123863012749	Uncharacterized conserved protein [Function unknown]; Region: COG0432
1123863012750	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1123863012751	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863012752	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863012753	homodimer interface [polypeptide binding]; other site
1123863012754	catalytic residue [active]
1123863012755	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1123863012756	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1123863012757	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1123863012758	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
1123863012759	putative DNA binding site [nucleotide binding]; other site
1123863012760	putative Zn2+ binding site [ion binding]; other site
1123863012761	AsnC family; Region: AsnC_trans_reg; pfam01037
1123863012762	replicative DNA helicase; Provisional; Region: PRK08006
1123863012763	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1123863012764	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1123863012765	Walker A motif; other site
1123863012766	ATP binding site [chemical binding]; other site
1123863012767	Walker B motif; other site
1123863012768	DNA binding loops [nucleotide binding]
1123863012769	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1123863012770	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1123863012771	NADP binding site [chemical binding]; other site
1123863012772	dimer interface [polypeptide binding]; other site
1123863012773	phage shock protein G; Reviewed; Region: pspG; PRK09459
1123863012774	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1123863012775	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1123863012776	FMN binding site [chemical binding]; other site
1123863012777	active site
1123863012778	catalytic residues [active]
1123863012779	substrate binding site [chemical binding]; other site
1123863012780	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1123863012781	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1123863012782	metal binding site 2 [ion binding]; metal-binding site
1123863012783	putative DNA binding helix; other site
1123863012784	metal binding site 1 [ion binding]; metal-binding site
1123863012785	dimer interface [polypeptide binding]; other site
1123863012786	structural Zn2+ binding site [ion binding]; other site
1123863012787	hypothetical protein; Provisional; Region: PRK10428
1123863012788	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1123863012789	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1123863012790	LexA repressor; Validated; Region: PRK00215
1123863012791	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1123863012792	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1123863012793	Catalytic site [active]
1123863012794	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1123863012795	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1123863012796	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1123863012797	putative acyl-acceptor binding pocket; other site
1123863012798	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1123863012799	UbiA prenyltransferase family; Region: UbiA; pfam01040
1123863012800	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1123863012801	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1123863012802	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
1123863012803	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1123863012804	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1123863012805	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1123863012806	Sodium Bile acid symporter family; Region: SBF; pfam01758
1123863012807	aspartate kinase III; Validated; Region: PRK09084
1123863012808	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1123863012809	nucleotide binding site [chemical binding]; other site
1123863012810	substrate binding site [chemical binding]; other site
1123863012811	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1123863012812	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1123863012813	dimer interface [polypeptide binding]; other site
1123863012814	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1123863012815	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1123863012816	active site
1123863012817	dimer interface [polypeptide binding]; other site
1123863012818	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1123863012819	dimer interface [polypeptide binding]; other site
1123863012820	active site
1123863012821	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1123863012822	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1123863012823	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1123863012824	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1123863012825	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1123863012826	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1123863012827	substrate binding pocket [chemical binding]; other site
1123863012828	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1123863012829	B12 binding site [chemical binding]; other site
1123863012830	cobalt ligand [ion binding]; other site
1123863012831	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1123863012832	transcriptional repressor IclR; Provisional; Region: PRK11569
1123863012833	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1123863012834	Bacterial transcriptional regulator; Region: IclR; pfam01614
1123863012835	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1123863012836	Beta-lactamase; Region: Beta-lactamase; pfam00144
1123863012837	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1123863012838	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1123863012839	putative outer membrane porin protein; Provisional; Region: PRK11379
1123863012840	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1123863012841	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863012842	DNA-binding site [nucleotide binding]; DNA binding site
1123863012843	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1123863012844	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1123863012845	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1123863012846	isocitrate lyase; Provisional; Region: PRK15063
1123863012847	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1123863012848	tetramer interface [polypeptide binding]; other site
1123863012849	active site
1123863012850	Mg2+/Mn2+ binding site [ion binding]; other site
1123863012851	malate synthase A; Region: malate_syn_A; TIGR01344
1123863012852	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1123863012853	active site
1123863012854	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1123863012855	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1123863012856	proposed active site lysine [active]
1123863012857	conserved cys residue [active]
1123863012858	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1123863012859	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1123863012860	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1123863012861	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1123863012862	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1123863012863	putative ligand binding residues [chemical binding]; other site
1123863012864	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1123863012865	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1123863012866	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1123863012867	purine monophosphate binding site [chemical binding]; other site
1123863012868	dimer interface [polypeptide binding]; other site
1123863012869	putative catalytic residues [active]
1123863012870	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1123863012871	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1123863012872	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1123863012873	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1123863012874	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1123863012875	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1123863012876	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1123863012877	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1123863012878	IHF dimer interface [polypeptide binding]; other site
1123863012879	IHF - DNA interface [nucleotide binding]; other site
1123863012880	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1123863012881	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1123863012882	Active_site [active]
1123863012883	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1123863012884	substrate binding site [chemical binding]; other site
1123863012885	active site
1123863012886	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1123863012887	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1123863012888	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1123863012889	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1123863012890	putative NADH binding site [chemical binding]; other site
1123863012891	putative active site [active]
1123863012892	nudix motif; other site
1123863012893	putative metal binding site [ion binding]; other site
1123863012894	anti-RNA polymerase sigma 70 factor; Provisional; Region: PRK11718
1123863012895	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1123863012896	ThiC-associated domain; Region: ThiC-associated; pfam13667
1123863012897	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1123863012898	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1123863012899	thiamine phosphate binding site [chemical binding]; other site
1123863012900	active site
1123863012901	pyrophosphate binding site [ion binding]; other site
1123863012902	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1123863012903	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1123863012904	DNA-binding site [nucleotide binding]; DNA binding site
1123863012905	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1123863012906	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863012907	homodimer interface [polypeptide binding]; other site
1123863012908	catalytic residue [active]
1123863012909	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1123863012910	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1123863012911	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1123863012912	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1123863012913	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1123863012914	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1123863012915	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1123863012916	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1123863012917	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1123863012918	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1123863012919	DNA binding site [nucleotide binding]
1123863012920	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1123863012921	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1123863012922	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1123863012923	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1123863012924	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1123863012925	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1123863012926	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1123863012927	RPB3 interaction site [polypeptide binding]; other site
1123863012928	RPB1 interaction site [polypeptide binding]; other site
1123863012929	RPB11 interaction site [polypeptide binding]; other site
1123863012930	RPB10 interaction site [polypeptide binding]; other site
1123863012931	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1123863012932	L11 interface [polypeptide binding]; other site
1123863012933	putative EF-Tu interaction site [polypeptide binding]; other site
1123863012934	putative EF-G interaction site [polypeptide binding]; other site
1123863012935	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1123863012936	23S rRNA interface [nucleotide binding]; other site
1123863012937	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1123863012938	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1123863012939	mRNA/rRNA interface [nucleotide binding]; other site
1123863012940	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1123863012941	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1123863012942	23S rRNA interface [nucleotide binding]; other site
1123863012943	L7/L12 interface [polypeptide binding]; other site
1123863012944	putative thiostrepton binding site; other site
1123863012945	L25 interface [polypeptide binding]; other site
1123863012946	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1123863012947	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1123863012948	putative homodimer interface [polypeptide binding]; other site
1123863012949	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1123863012950	heterodimer interface [polypeptide binding]; other site
1123863012951	homodimer interface [polypeptide binding]; other site
1123863012952	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1123863012953	elongation factor Tu; Reviewed; Region: PRK00049
1123863012954	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1123863012955	G1 box; other site
1123863012956	GEF interaction site [polypeptide binding]; other site
1123863012957	GTP/Mg2+ binding site [chemical binding]; other site
1123863012958	Switch I region; other site
1123863012959	G2 box; other site
1123863012960	G3 box; other site
1123863012961	Switch II region; other site
1123863012962	G4 box; other site
1123863012963	G5 box; other site
1123863012964	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1123863012965	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1123863012966	Antibiotic Binding Site [chemical binding]; other site
1123863012967	pantothenate kinase; Provisional; Region: PRK05439
1123863012968	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1123863012969	ATP-binding site [chemical binding]; other site
1123863012970	CoA-binding site [chemical binding]; other site
1123863012971	Mg2+-binding site [ion binding]; other site
1123863012972	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1123863012973	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1123863012974	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1123863012975	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1123863012976	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1123863012977	FAD binding domain; Region: FAD_binding_4; pfam01565
1123863012978	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1123863012979	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1123863012980	potassium transporter; Provisional; Region: PRK10750
1123863012981	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1123863012982	hypothetical protein; Provisional; Region: PRK11568
1123863012983	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1123863012984	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1123863012985	proline dipeptidase; Provisional; Region: PRK13607
1123863012986	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1123863012987	active site
1123863012988	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1123863012989	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1123863012990	substrate binding site [chemical binding]; other site
1123863012991	oxyanion hole (OAH) forming residues; other site
1123863012992	trimer interface [polypeptide binding]; other site
1123863012993	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1123863012994	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1123863012995	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1123863012996	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1123863012997	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1123863012998	dimer interface [polypeptide binding]; other site
1123863012999	active site
1123863013000	FMN reductase; Validated; Region: fre; PRK08051
1123863013001	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1123863013002	FAD binding pocket [chemical binding]; other site
1123863013003	FAD binding motif [chemical binding]; other site
1123863013004	phosphate binding motif [ion binding]; other site
1123863013005	beta-alpha-beta structure motif; other site
1123863013006	NAD binding pocket [chemical binding]; other site
1123863013007	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
1123863013008	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1123863013009	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1123863013010	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1123863013011	active site
1123863013012	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1123863013013	sec-independent translocase; Provisional; Region: PRK01770
1123863013014	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1123863013015	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1123863013016	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1123863013017	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1123863013018	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1123863013019	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1123863013020	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1123863013021	S-adenosylmethionine binding site [chemical binding]; other site
1123863013022	DNA recombination protein RmuC; Provisional; Region: PRK10361
1123863013023	RmuC family; Region: RmuC; pfam02646
1123863013024	uridine phosphorylase; Provisional; Region: PRK11178
1123863013025	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1123863013026	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1123863013027	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1123863013028	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1123863013029	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1123863013030	THF binding site; other site
1123863013031	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1123863013032	substrate binding site [chemical binding]; other site
1123863013033	THF binding site; other site
1123863013034	zinc-binding site [ion binding]; other site
1123863013035	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1123863013036	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863013037	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1123863013038	putative dimerization interface [polypeptide binding]; other site
1123863013039	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1123863013040	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1123863013041	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1123863013042	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1123863013043	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1123863013044	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863013045	putative substrate translocation pore; other site
1123863013046	putative hydrolase; Provisional; Region: PRK10976
1123863013047	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863013048	active site
1123863013049	motif I; other site
1123863013050	motif II; other site
1123863013051	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863013052	lysophospholipase L2; Provisional; Region: PRK10749
1123863013053	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1123863013054	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1123863013055	threonine efflux system; Provisional; Region: PRK10229
1123863013056	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1123863013057	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1123863013058	ATP binding site [chemical binding]; other site
1123863013059	putative Mg++ binding site [ion binding]; other site
1123863013060	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863013061	nucleotide binding region [chemical binding]; other site
1123863013062	ATP-binding site [chemical binding]; other site
1123863013063	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1123863013064	HRDC domain; Region: HRDC; pfam00570
1123863013065	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1123863013066	dimerization interface [polypeptide binding]; other site
1123863013067	substrate binding site [chemical binding]; other site
1123863013068	active site
1123863013069	calcium binding site [ion binding]; other site
1123863013070	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1123863013071	CoenzymeA binding site [chemical binding]; other site
1123863013072	subunit interaction site [polypeptide binding]; other site
1123863013073	PHB binding site; other site
1123863013074	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1123863013075	Predicted transcriptional regulators [Transcription]; Region: COG1733
1123863013076	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863013077	dimerization interface [polypeptide binding]; other site
1123863013078	putative DNA binding site [nucleotide binding]; other site
1123863013079	putative Zn2+ binding site [ion binding]; other site
1123863013080	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1123863013081	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1123863013082	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1123863013083	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1123863013084	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1123863013085	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1123863013086	Cl binding site [ion binding]; other site
1123863013087	oligomer interface [polypeptide binding]; other site
1123863013088	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1123863013089	Part of AAA domain; Region: AAA_19; pfam13245
1123863013090	Family description; Region: UvrD_C_2; pfam13538
1123863013091	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1123863013092	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863013093	motif II; other site
1123863013094	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1123863013095	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1123863013096	active site
1123863013097	DNA binding site [nucleotide binding]
1123863013098	Int/Topo IB signature motif; other site
1123863013099	hypothetical protein; Provisional; Region: PRK10963
1123863013100	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1123863013101	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1123863013102	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1123863013103	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; cl02361
1123863013104	adenylate cyclase; Provisional; Region: cyaA; PRK09450
1123863013105	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1123863013106	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1123863013107	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1123863013108	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1123863013109	active site
1123863013110	domain interfaces; other site
1123863013111	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1123863013112	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1123863013113	active site
1123863013114	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1123863013115	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1123863013116	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1123863013117	HemY protein N-terminus; Region: HemY_N; pfam07219
1123863013118	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1123863013119	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1123863013120	putative common antigen polymerase; Provisional; Region: PRK02975
1123863013121	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; cl07929
1123863013122	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1123863013123	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1123863013124	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1123863013125	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1123863013126	inhibitor-cofactor binding pocket; inhibition site
1123863013127	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863013128	catalytic residue [active]
1123863013129	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1123863013130	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863013131	Coenzyme A binding pocket [chemical binding]; other site
1123863013132	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1123863013133	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1123863013134	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1123863013135	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1123863013136	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1123863013137	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1123863013138	active site
1123863013139	homodimer interface [polypeptide binding]; other site
1123863013140	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1123863013141	Chain length determinant protein; Region: Wzz; pfam02706
1123863013142	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1123863013143	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1123863013144	Mg++ binding site [ion binding]; other site
1123863013145	putative catalytic motif [active]
1123863013146	substrate binding site [chemical binding]; other site
1123863013147	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1123863013148	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1123863013149	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1123863013150	RNA binding site [nucleotide binding]; other site
1123863013151	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1123863013152	multimer interface [polypeptide binding]; other site
1123863013153	Walker A motif; other site
1123863013154	ATP binding site [chemical binding]; other site
1123863013155	Walker B motif; other site
1123863013156	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1123863013157	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1123863013158	catalytic residues [active]
1123863013159	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1123863013160	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1123863013161	ATP binding site [chemical binding]; other site
1123863013162	Mg++ binding site [ion binding]; other site
1123863013163	motif III; other site
1123863013164	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1123863013165	nucleotide binding region [chemical binding]; other site
1123863013166	ATP-binding site [chemical binding]; other site
1123863013167	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1123863013168	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1123863013169	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1123863013170	Part of AAA domain; Region: AAA_19; pfam13245
1123863013171	Family description; Region: UvrD_C_2; pfam13538
1123863013172	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
1123863013173	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1123863013174	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1123863013175	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863013176	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1123863013177	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1123863013178	substrate binding site [chemical binding]; other site
1123863013179	ATP binding site [chemical binding]; other site
1123863013180	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863013181	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_10; cd07251
1123863013182	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1123863013183	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1123863013184	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1123863013185	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1123863013186	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1123863013187	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1123863013188	putative diguanylate cyclase; Provisional; Region: PRK13561
1123863013189	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863013190	metal binding site [ion binding]; metal-binding site
1123863013191	active site
1123863013192	I-site; other site
1123863013193	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863013194	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
1123863013195	Cellulose synthase subunit D; Region: Cellsynth_D; pfam03500
1123863013196	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1123863013197	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1123863013198	binding surface
1123863013199	TPR motif; other site
1123863013200	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1123863013201	cellulose synthase regulator protein; Provisional; Region: PRK11114
1123863013202	cellulose synthase catalytic subunit (UDP-forming); Region: CelA; TIGR03030
1123863013203	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1123863013204	DXD motif; other site
1123863013205	PilZ domain; Region: PilZ; pfam07238
1123863013206	cellulose synthase operon protein YhjQ; Region: cellulose_yhjQ; TIGR03371
1123863013207	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1123863013208	P-loop; other site
1123863013209	Magnesium ion binding site [ion binding]; other site
1123863013210	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1123863013211	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863013212	Walker A/P-loop; other site
1123863013213	ATP binding site [chemical binding]; other site
1123863013214	Q-loop/lid; other site
1123863013215	ABC transporter signature motif; other site
1123863013216	Walker B; other site
1123863013217	D-loop; other site
1123863013218	H-loop/switch region; other site
1123863013219	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1123863013220	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1123863013221	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863013222	Walker A/P-loop; other site
1123863013223	ATP binding site [chemical binding]; other site
1123863013224	Q-loop/lid; other site
1123863013225	ABC transporter signature motif; other site
1123863013226	Walker B; other site
1123863013227	D-loop; other site
1123863013228	H-loop/switch region; other site
1123863013229	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1123863013230	dipeptide transporter; Provisional; Region: PRK10913
1123863013231	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1123863013232	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863013233	dimer interface [polypeptide binding]; other site
1123863013234	conserved gate region; other site
1123863013235	putative PBP binding loops; other site
1123863013236	ABC-ATPase subunit interface; other site
1123863013237	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1123863013238	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863013239	dimer interface [polypeptide binding]; other site
1123863013240	conserved gate region; other site
1123863013241	putative PBP binding loops; other site
1123863013242	ABC-ATPase subunit interface; other site
1123863013243	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1123863013244	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1123863013245	peptide binding site [polypeptide binding]; other site
1123863013246	phosphoethanolamine transferase; Provisional; Region: PRK11560
1123863013247	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1123863013248	Sulfatase; Region: Sulfatase; pfam00884
1123863013249	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1123863013250	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1123863013251	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1123863013252	putative Zn2+ binding site [ion binding]; other site
1123863013253	putative DNA binding site [nucleotide binding]; other site
1123863013254	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1123863013255	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1123863013256	Zn2+ binding site [ion binding]; other site
1123863013257	Mg2+ binding site [ion binding]; other site
1123863013258	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
1123863013259	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1123863013260	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1123863013261	catalytic residue [active]
1123863013262	tryptophan permease TnaB; Provisional; Region: PRK09664
1123863013263	aromatic amino acid transport protein; Region: araaP; TIGR00837
1123863013264	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863013265	non-specific DNA binding site [nucleotide binding]; other site
1123863013266	salt bridge; other site
1123863013267	sequence-specific DNA binding site [nucleotide binding]; other site
1123863013268	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1123863013269	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1123863013270	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1123863013271	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1123863013272	active site
1123863013273	P-loop; other site
1123863013274	phosphorylation site [posttranslational modification]
1123863013275	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1123863013276	active site
1123863013277	phosphorylation site [posttranslational modification]
1123863013278	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1123863013279	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1123863013280	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1123863013281	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1123863013282	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1123863013283	hypothetical protein; Provisional; Region: PRK11020
1123863013284	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1123863013285	superoxide dismutase; Provisional; Region: PRK10925
1123863013286	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1123863013287	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1123863013288	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1123863013289	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1123863013290	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1123863013291	putative glutathione S-transferase; Provisional; Region: PRK10357
1123863013292	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1123863013293	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1123863013294	dimer interface [polypeptide binding]; other site
1123863013295	N-terminal domain interface [polypeptide binding]; other site
1123863013296	putative substrate binding pocket (H-site) [chemical binding]; other site
1123863013297	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1123863013298	MltA-interacting protein MipA; Region: MipA; cl01504
1123863013299	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1123863013300	DALR anticodon binding domain; Region: DALR_1; pfam05746
1123863013301	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1123863013302	dimer interface [polypeptide binding]; other site
1123863013303	motif 1; other site
1123863013304	active site
1123863013305	motif 2; other site
1123863013306	motif 3; other site
1123863013307	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1123863013308	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1123863013309	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1123863013310	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863013311	active site
1123863013312	motif I; other site
1123863013313	motif II; other site
1123863013314	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1123863013315	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1123863013316	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
1123863013317	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
1123863013318	putative FMN binding site [chemical binding]; other site
1123863013319	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1123863013320	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1123863013321	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1123863013322	G1 box; other site
1123863013323	GTP/Mg2+ binding site [chemical binding]; other site
1123863013324	Switch I region; other site
1123863013325	G2 box; other site
1123863013326	Switch II region; other site
1123863013327	G3 box; other site
1123863013328	G4 box; other site
1123863013329	G5 box; other site
1123863013330	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1123863013331	membrane protein insertase; Provisional; Region: PRK01318
1123863013332	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1123863013333	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1123863013334	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1123863013335	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1123863013336	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1123863013337	P-loop; other site
1123863013338	Magnesium ion binding site [ion binding]; other site
1123863013339	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1123863013340	Magnesium ion binding site [ion binding]; other site
1123863013341	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1123863013342	ParB-like nuclease domain; Region: ParBc; pfam02195
1123863013343	ParB family; Region: ParB; pfam08775
1123863013344	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1123863013345	homotrimer interaction site [polypeptide binding]; other site
1123863013346	putative active site [active]
1123863013347	potential frameshift: common BLAST hit: gi|292899748|ref|YP_003539117.1| membrane protein
1123863013348	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1123863013349	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1123863013350	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1123863013351	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1123863013352	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1123863013353	metal binding site [ion binding]; metal-binding site
1123863013354	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1123863013355	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1123863013356	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1123863013357	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863013358	ABC-ATPase subunit  interface; other site
1123863013359	dimer interface [polypeptide binding]; other site
1123863013360	putative PBP binding regions; other site
1123863013361	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1123863013362	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1123863013363	ABC-ATPase subunit  interface; other site
1123863013364	dimer interface [polypeptide binding]; other site
1123863013365	putative PBP binding regions; other site
1123863013366	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
1123863013367	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1123863013368	catalytic loop [active]
1123863013369	iron binding site [ion binding]; other site
1123863013370	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1123863013371	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1123863013372	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
1123863013373	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1123863013374	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1123863013375	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1123863013376	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1123863013377	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1123863013378	Ligand binding site; other site
1123863013379	metal-binding site
1123863013380	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1123863013381	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1123863013382	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1123863013383	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1123863013384	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
1123863013385	putative ligand binding residues [chemical binding]; other site
1123863013386	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1123863013387	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863013388	N-terminal plug; other site
1123863013389	ligand-binding site [chemical binding]; other site
1123863013390	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1123863013391	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1123863013392	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1123863013393	putative active site [active]
1123863013394	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1123863013395	active site
1123863013396	oxyanion hole [active]
1123863013397	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1123863013398	catalytic triad [active]
1123863013399	Autotransporter beta-domain; Region: Autotransporter; cl17461
1123863013400	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1123863013401	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1123863013402	RNA binding surface [nucleotide binding]; other site
1123863013403	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1123863013404	probable active site [active]
1123863013405	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
1123863013406	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1123863013407	GAF domain; Region: GAF; pfam01590
1123863013408	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863013409	Sensors of blue-light using FAD; Region: BLUF; pfam04940
1123863013410	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863013411	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1123863013412	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1123863013413	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863013414	GAF domain; Region: GAF; pfam01590
1123863013415	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1123863013416	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1123863013417	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863013418	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
1123863013419	beta-galactosidase; Region: BGL; TIGR03356
1123863013420	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
1123863013421	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1123863013422	active site turn [active]
1123863013423	phosphorylation site [posttranslational modification]
1123863013424	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1123863013425	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863013426	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863013427	DNA binding site [nucleotide binding]
1123863013428	domain linker motif; other site
1123863013429	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1123863013430	dimerization interface (closed form) [polypeptide binding]; other site
1123863013431	ligand binding site [chemical binding]; other site
1123863013432	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1123863013433	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1123863013434	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1123863013435	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1123863013436	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1123863013437	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863013438	active site
1123863013439	motif I; other site
1123863013440	motif II; other site
1123863013441	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1123863013442	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1123863013443	MASE2 domain; Region: MASE2; pfam05230
1123863013444	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863013445	metal binding site [ion binding]; metal-binding site
1123863013446	active site
1123863013447	I-site; other site
1123863013448	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1123863013449	active site
1123863013450	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
1123863013451	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; cl01346
1123863013452	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1123863013453	active site
1123863013454	DNA binding site [nucleotide binding]
1123863013455	Int/Topo IB signature motif; other site
1123863013456	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1123863013457	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1123863013458	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1123863013459	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1123863013460	N-terminal plug; other site
1123863013461	ligand-binding site [chemical binding]; other site
1123863013462	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1123863013463	active site
1123863013464	dimerization interface [polypeptide binding]; other site
1123863013465	potential frameshift: common BLAST hit: gi|317054381|ref|YP_004118406.1| Sir2 family NAD-dependent protein deacetylase
1123863013466	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1123863013467	SIR2-like domain; Region: SIR2_2; pfam13289
1123863013468	YebG protein; Region: YebG; pfam07130
1123863013469	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
1123863013470	Cache domain; Region: Cache_1; pfam02743
1123863013471	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863013472	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863013473	dimer interface [polypeptide binding]; other site
1123863013474	putative CheW interface [polypeptide binding]; other site
1123863013475	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1123863013476	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1123863013477	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1123863013478	NAD(P) binding site [chemical binding]; other site
1123863013479	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863013480	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863013481	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1123863013482	putative dimerization interface [polypeptide binding]; other site
1123863013483	putative substrate binding pocket [chemical binding]; other site
1123863013484	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
1123863013485	acetolactate synthase; Reviewed; Region: PRK08617
1123863013486	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1123863013487	PYR/PP interface [polypeptide binding]; other site
1123863013488	dimer interface [polypeptide binding]; other site
1123863013489	TPP binding site [chemical binding]; other site
1123863013490	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1123863013491	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
1123863013492	TPP-binding site [chemical binding]; other site
1123863013493	acetoin reductase; Validated; Region: PRK08643
1123863013494	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
1123863013495	NAD binding site [chemical binding]; other site
1123863013496	homotetramer interface [polypeptide binding]; other site
1123863013497	homodimer interface [polypeptide binding]; other site
1123863013498	active site
1123863013499	substrate binding site [chemical binding]; other site
1123863013500	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558
1123863013501	SnoaL-like domain; Region: SnoaL_2; pfam12680
1123863013502	riboflavin synthase subunit beta; Provisional; Region: PRK12419
1123863013503	active site
1123863013504	homopentamer interface [polypeptide binding]; other site
1123863013505	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1123863013506	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
1123863013507	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1123863013508	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1123863013509	Cupin domain; Region: Cupin_2; cl17218
1123863013510	short chain dehydrogenase; Provisional; Region: PRK07577
1123863013511	classical (c) SDRs; Region: SDR_c; cd05233
1123863013512	NAD(P) binding site [chemical binding]; other site
1123863013513	active site
1123863013514	Domain of unknown function (DUF386); Region: DUF386; cl01047
1123863013515	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1123863013516	BNR repeat-like domain; Region: BNR_2; pfam13088
1123863013517	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1123863013518	Na binding site [ion binding]; other site
1123863013519	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1123863013520	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1123863013521	inhibitor site; inhibition site
1123863013522	active site
1123863013523	dimer interface [polypeptide binding]; other site
1123863013524	catalytic residue [active]
1123863013525	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1123863013526	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1123863013527	active site
1123863013528	NAD binding site [chemical binding]; other site
1123863013529	metal binding site [ion binding]; metal-binding site
1123863013530	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
1123863013531	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1123863013532	tyrosine phenol-lyase; Provisional; Region: PRK13237
1123863013533	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
1123863013534	substrate binding site [chemical binding]; other site
1123863013535	tetramer interface [polypeptide binding]; other site
1123863013536	catalytic residue [active]
1123863013537	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
1123863013538	aromatic amino acid transport protein; Region: araaP; TIGR00837
1123863013539	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1123863013540	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1123863013541	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1123863013542	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1123863013543	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1123863013544	substrate binding pocket [chemical binding]; other site
1123863013545	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1123863013546	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1123863013547	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1123863013548	EamA-like transporter family; Region: EamA; pfam00892
1123863013549	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1123863013550	EamA-like transporter family; Region: EamA; pfam00892
1123863013551	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1123863013552	putative active site pocket [active]
1123863013553	dimerization interface [polypeptide binding]; other site
1123863013554	putative catalytic residue [active]
1123863013555	HAMP domain; Region: HAMP; pfam00672
1123863013556	dimerization interface [polypeptide binding]; other site
1123863013557	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863013558	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863013559	dimer interface [polypeptide binding]; other site
1123863013560	putative CheW interface [polypeptide binding]; other site
1123863013561	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1123863013562	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1123863013563	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1123863013564	HlyD family secretion protein; Region: HlyD_3; pfam13437
1123863013565	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1123863013566	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1123863013567	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1123863013568	dimer interface [polypeptide binding]; other site
1123863013569	phosphorylation site [posttranslational modification]
1123863013570	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863013571	ATP binding site [chemical binding]; other site
1123863013572	Mg2+ binding site [ion binding]; other site
1123863013573	G-X-G motif; other site
1123863013574	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1123863013575	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863013576	active site
1123863013577	phosphorylation site [posttranslational modification]
1123863013578	intermolecular recognition site; other site
1123863013579	dimerization interface [polypeptide binding]; other site
1123863013580	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1123863013581	DNA binding site [nucleotide binding]
1123863013582	MltA-interacting protein MipA; Region: MipA; cl01504
1123863013583	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863013584	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
1123863013585	dimer interface [polypeptide binding]; other site
1123863013586	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863013587	ligand binding site [chemical binding]; other site
1123863013588	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1123863013589	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1123863013590	inhibitor-cofactor binding pocket; inhibition site
1123863013591	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863013592	catalytic residue [active]
1123863013593	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1123863013594	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1123863013595	Ligand binding site; other site
1123863013596	Putative Catalytic site; other site
1123863013597	DXD motif; other site
1123863013598	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1123863013599	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1123863013600	active site
1123863013601	substrate binding site [chemical binding]; other site
1123863013602	cosubstrate binding site; other site
1123863013603	catalytic site [active]
1123863013604	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1123863013605	active site
1123863013606	hexamer interface [polypeptide binding]; other site
1123863013607	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1123863013608	NAD binding site [chemical binding]; other site
1123863013609	substrate binding site [chemical binding]; other site
1123863013610	active site
1123863013611	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1123863013612	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1123863013613	putative active site [active]
1123863013614	putative catalytic site [active]
1123863013615	putative Zn binding site [ion binding]; other site
1123863013616	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1123863013617	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1123863013618	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1123863013619	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1123863013620	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863013621	dimerization interface [polypeptide binding]; other site
1123863013622	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863013623	dimer interface [polypeptide binding]; other site
1123863013624	putative CheW interface [polypeptide binding]; other site
1123863013625	chorismate mutase; Provisional; Region: PRK08055
1123863013626	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1123863013627	Putative glucoamylase; Region: Glycoamylase; pfam10091
1123863013628	Second GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_2_like; cd11753
1123863013629	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1123863013630	First GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_1_like; cd11756
1123863013631	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
1123863013632	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1123863013633	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863013634	non-specific DNA binding site [nucleotide binding]; other site
1123863013635	salt bridge; other site
1123863013636	sequence-specific DNA binding site [nucleotide binding]; other site
1123863013637	Cupin domain; Region: Cupin_2; pfam07883
1123863013638	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1123863013639	B3/4 domain; Region: B3_4; pfam03483
1123863013640	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1123863013641	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1123863013642	inhibitor site; inhibition site
1123863013643	active site
1123863013644	dimer interface [polypeptide binding]; other site
1123863013645	catalytic residue [active]
1123863013646	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
1123863013647	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1123863013648	active site
1123863013649	DNA binding site [nucleotide binding]
1123863013650	Int/Topo IB signature motif; other site
1123863013651	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1123863013652	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863013653	topology modulation protein; Reviewed; Region: PRK08118
1123863013654	AAA domain; Region: AAA_17; pfam13207
1123863013655	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1123863013656	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1123863013657	inhibitor site; inhibition site
1123863013658	active site
1123863013659	dimer interface [polypeptide binding]; other site
1123863013660	catalytic residue [active]
1123863013661	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863013662	Coenzyme A binding pocket [chemical binding]; other site
1123863013663	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863013664	putative CheW interface [polypeptide binding]; other site
1123863013665	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1123863013666	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1123863013667	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1123863013668	glucose-6-phosphate 1-dehydrogenase; Provisional; Region: PRK12853
1123863013669	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1123863013670	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1123863013671	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1123863013672	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
1123863013673	Glycoside hydrolase family 15, N-terminal domain; Region: GH15_N; cd07430
1123863013674	Domain interface; other site
1123863013675	glucan 1,4-alpha-glucosidase; Region: glucan_glucosid; TIGR01535
1123863013676	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
1123863013677	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1123863013678	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1123863013679	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1123863013680	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1123863013681	Predicted flavoprotein [General function prediction only]; Region: COG0431
1123863013682	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1123863013683	flagellin; Provisional; Region: PRK12802
1123863013684	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1123863013685	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1123863013686	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1123863013687	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1123863013688	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1123863013689	RES domain; Region: RES; pfam08808
1123863013690	Protein of unknown function (DUF2384); Region: DUF2384; cl17718
1123863013691	putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293
1123863013692	KTSC domain; Region: KTSC; pfam13619
1123863013693	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1123863013694	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863013695	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1123863013696	potential frameshift: common BLAST hit: gi|322833711|ref|YP_004213738.1| pyrimidine utilization protein A
1123863013697	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1123863013698	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1123863013699	Isochorismatase family; Region: Isochorismatase; pfam00857
1123863013700	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1123863013701	catalytic triad [active]
1123863013702	conserved cis-peptide bond; other site
1123863013703	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1123863013704	homotrimer interaction site [polypeptide binding]; other site
1123863013705	putative active site [active]
1123863013706	pyrimidine utilization protein D; Region: RutD; TIGR03611
1123863013707	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
1123863013708	putative FMN binding site [chemical binding]; other site
1123863013709	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
1123863013710	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
1123863013711	Protein of unknown function (DUF1611); Region: DUF1611; pfam07755
1123863013712	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1123863013713	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1123863013714	active site
1123863013715	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1123863013716	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863013717	Walker A/P-loop; other site
1123863013718	ATP binding site [chemical binding]; other site
1123863013719	Q-loop/lid; other site
1123863013720	ABC transporter signature motif; other site
1123863013721	Walker B; other site
1123863013722	D-loop; other site
1123863013723	H-loop/switch region; other site
1123863013724	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1123863013725	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863013726	Walker A/P-loop; other site
1123863013727	ATP binding site [chemical binding]; other site
1123863013728	Q-loop/lid; other site
1123863013729	ABC transporter signature motif; other site
1123863013730	Walker B; other site
1123863013731	D-loop; other site
1123863013732	H-loop/switch region; other site
1123863013733	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1123863013734	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1123863013735	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1123863013736	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1123863013737	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863013738	dimer interface [polypeptide binding]; other site
1123863013739	conserved gate region; other site
1123863013740	putative PBP binding loops; other site
1123863013741	ABC-ATPase subunit interface; other site
1123863013742	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1123863013743	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1123863013744	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863013745	dimer interface [polypeptide binding]; other site
1123863013746	conserved gate region; other site
1123863013747	putative PBP binding loops; other site
1123863013748	ABC-ATPase subunit interface; other site
1123863013749	L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253
1123863013750	homodimer interface [polypeptide binding]; other site
1123863013751	homotetramer interface [polypeptide binding]; other site
1123863013752	active site pocket [active]
1123863013753	cleavage site
1123863013754	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA_1; cd08663
1123863013755	SxDxEG motif; other site
1123863013756	active site
1123863013757	metal binding site [ion binding]; metal-binding site
1123863013758	homopentamer interface [polypeptide binding]; other site
1123863013759	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863013760	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863013761	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1123863013762	dimerization interface [polypeptide binding]; other site
1123863013763	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1123863013764	PAS domain; Region: PAS_9; pfam13426
1123863013765	putative active site [active]
1123863013766	heme pocket [chemical binding]; other site
1123863013767	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863013768	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863013769	metal binding site [ion binding]; metal-binding site
1123863013770	active site
1123863013771	I-site; other site
1123863013772	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1123863013773	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1123863013774	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1123863013775	domain linker motif; other site
1123863013776	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1123863013777	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1123863013778	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1123863013779	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1123863013780	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1123863013781	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1123863013782	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1123863013783	Metal-binding active site; metal-binding site
1123863013784	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1123863013785	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1123863013786	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1123863013787	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863013788	non-specific DNA binding site [nucleotide binding]; other site
1123863013789	salt bridge; other site
1123863013790	sequence-specific DNA binding site [nucleotide binding]; other site
1123863013791	Cupin domain; Region: Cupin_2; pfam07883
1123863013792	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1123863013793	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1123863013794	substrate binding pocket [chemical binding]; other site
1123863013795	membrane-bound complex binding site; other site
1123863013796	hinge residues; other site
1123863013797	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863013798	dimer interface [polypeptide binding]; other site
1123863013799	conserved gate region; other site
1123863013800	putative PBP binding loops; other site
1123863013801	ABC-ATPase subunit interface; other site
1123863013802	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1123863013803	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1123863013804	Walker A/P-loop; other site
1123863013805	ATP binding site [chemical binding]; other site
1123863013806	Q-loop/lid; other site
1123863013807	ABC transporter signature motif; other site
1123863013808	Walker B; other site
1123863013809	D-loop; other site
1123863013810	H-loop/switch region; other site
1123863013811	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863013812	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863013813	dimer interface [polypeptide binding]; other site
1123863013814	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1123863013815	putative CheW interface [polypeptide binding]; other site
1123863013816	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1123863013817	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1123863013818	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863013819	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863013820	dimerization interface [polypeptide binding]; other site
1123863013821	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863013822	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863013823	dimer interface [polypeptide binding]; other site
1123863013824	putative CheW interface [polypeptide binding]; other site
1123863013825	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1123863013826	active site
1123863013827	DNA binding site [nucleotide binding]
1123863013828	Int/Topo IB signature motif; other site
1123863013829	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1123863013830	potential protein location (hypothetical protein) that overlaps protein (response regulator receiver domain-containing protein)
1123863013831	potential protein location (hypothetical protein) that overlaps protein (hypothetical protein)
1123863013832	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1123863013833	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863013834	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863013835	Walker A/P-loop; other site
1123863013836	Walker A/P-loop; other site
1123863013837	ATP binding site [chemical binding]; other site
1123863013838	ATP binding site [chemical binding]; other site
1123863013839	Q-loop/lid; other site
1123863013840	ABC transporter signature motif; other site
1123863013841	Walker B; other site
1123863013842	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863013843	Walker B; other site
1123863013844	D-loop; other site
1123863013845	H-loop/switch region; other site
1123863013846	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1123863013847	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1123863013848	urea carboxylase; Region: urea_carbox; TIGR02712
1123863013849	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1123863013850	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1123863013851	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1123863013852	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1123863013853	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1123863013854	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1123863013855	carboxyltransferase (CT) interaction site; other site
1123863013856	biotinylation site [posttranslational modification]; other site
1123863013857	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1123863013858	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
1123863013859	urea carboxylase-associated protein 2; Region: urea_degr_2; TIGR03425
1123863013860	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1123863013861	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1123863013862	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1123863013863	Walker A/P-loop; other site
1123863013864	ATP binding site [chemical binding]; other site
1123863013865	Q-loop/lid; other site
1123863013866	ABC transporter signature motif; other site
1123863013867	Walker B; other site
1123863013868	D-loop; other site
1123863013869	H-loop/switch region; other site
1123863013870	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1123863013871	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863013872	dimer interface [polypeptide binding]; other site
1123863013873	conserved gate region; other site
1123863013874	putative PBP binding loops; other site
1123863013875	ABC-ATPase subunit interface; other site
1123863013876	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1123863013877	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
1123863013878	Protein of unknown function (DUF1345); Region: DUF1345; pfam07077
1123863013879	Protein of unknown function (DUF861); Region: Cupin_3; cl17594
1123863013880	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1123863013881	aspartate racemase; Region: asp_race; TIGR00035
1123863013882	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
1123863013883	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1123863013884	DsbD alpha interface [polypeptide binding]; other site
1123863013885	catalytic residues [active]
1123863013886	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1123863013887	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1123863013888	catalytic triad [active]
1123863013889	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1123863013890	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1123863013891	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863013892	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863013893	dimerization interface [polypeptide binding]; other site
1123863013894	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1123863013895	active site
1123863013896	metal binding site [ion binding]; metal-binding site
1123863013897	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1123863013898	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1123863013899	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863013900	dimer interface [polypeptide binding]; other site
1123863013901	conserved gate region; other site
1123863013902	putative PBP binding loops; other site
1123863013903	ABC-ATPase subunit interface; other site
1123863013904	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1123863013905	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863013906	putative PBP binding loops; other site
1123863013907	ABC-ATPase subunit interface; other site
1123863013908	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1123863013909	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1123863013910	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1123863013911	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1123863013912	Walker A/P-loop; other site
1123863013913	ATP binding site [chemical binding]; other site
1123863013914	Q-loop/lid; other site
1123863013915	ABC transporter signature motif; other site
1123863013916	Walker B; other site
1123863013917	D-loop; other site
1123863013918	H-loop/switch region; other site
1123863013919	TOBE domain; Region: TOBE_2; pfam08402
1123863013920	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1123863013921	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863013922	EamA-like transporter family; Region: EamA; cl17759
1123863013923	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1123863013924	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1123863013925	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1123863013926	dimerization interface [polypeptide binding]; other site
1123863013927	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1123863013928	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1123863013929	dimer interface [polypeptide binding]; other site
1123863013930	putative CheW interface [polypeptide binding]; other site
1123863013931	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1123863013932	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1123863013933	LysE type translocator; Region: LysE; cl00565
1123863013934	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1123863013935	dimer interface [polypeptide binding]; other site
1123863013936	FMN binding site [chemical binding]; other site
1123863013937	NADPH bind site [chemical binding]; other site
1123863013938	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1123863013939	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1123863013940	metal binding site [ion binding]; metal-binding site
1123863013941	active site
1123863013942	I-site; other site
1123863013943	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1123863013944	Cytochrome c; Region: Cytochrom_C; pfam00034
1123863013945	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1123863013946	Cytochrome c; Region: Cytochrom_C; pfam00034
1123863013947	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1123863013948	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1123863013949	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1123863013950	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
1123863013951	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1123863013952	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1123863013953	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1123863013954	ABC transporter transmembrane region; Region: ABC_membrane_3; pfam13748
1123863013955	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1123863013956	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1123863013957	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1123863013958	diaminobutyrate--2-oxoglutarate aminotransferase; Provisional; Region: PRK06931
1123863013959	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1123863013960	inhibitor-cofactor binding pocket; inhibition site
1123863013961	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863013962	catalytic residue [active]
1123863013963	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1123863013964	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1123863013965	catalytic residue [active]
1123863013966	Protein of unknown function (DUF1203); Region: DUF1203; pfam06718
1123863013967	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
1123863013968	malate:quinone oxidoreductase; Validated; Region: PRK05257
1123863013969	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1123863013970	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1123863013971	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1123863013972	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1123863013973	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1123863013974	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1123863013975	ATP binding site [chemical binding]; other site
1123863013976	Mg2+ binding site [ion binding]; other site
1123863013977	G-X-G motif; other site
1123863013978	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1123863013979	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1123863013980	active site
1123863013981	phosphorylation site [posttranslational modification]
1123863013982	intermolecular recognition site; other site
1123863013983	dimerization interface [polypeptide binding]; other site
1123863013984	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1123863013985	ApbE family; Region: ApbE; pfam02424
1123863013986	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1123863013987	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1123863013988	putative active site [active]
1123863013989	putative FMN binding site [chemical binding]; other site
1123863013990	putative substrate binding site [chemical binding]; other site
1123863013991	putative catalytic residue [active]
1123863013992	FMN-binding domain; Region: FMN_bind; cl01081
1123863013993	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
1123863013994	L-aspartate oxidase; Provisional; Region: PRK06175
1123863013995	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1123863013996	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1123863013997	transmembrane helices; other site
1123863013998	fumarate hydratase; Provisional; Region: PRK15389
1123863013999	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1123863014000	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1123863014001	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1123863014002	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1123863014003	NAD(P) binding site [chemical binding]; other site
1123863014004	putative active site [active]
1123863014005	progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs; Region: 5beta-POR_like_SDR_a; cd08948
1123863014006	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1123863014007	NAD(P) binding site [chemical binding]; other site
1123863014008	active site
1123863014009	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1123863014010	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1123863014011	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1123863014012	dimerization interface [polypeptide binding]; other site
1123863014013	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
1123863014014	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1123863014015	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1123863014016	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863014017	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1123863014018	putative substrate translocation pore; other site
1123863014019	proline/glycine betaine transporter; Provisional; Region: PRK10642
1123863014020	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1123863014021	putative substrate translocation pore; other site
1123863014022	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1123863014023	substrate binding site [chemical binding]; other site
1123863014024	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1123863014025	ImpA domain protein; Region: DUF3702; pfam12486
1123863014026	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1123863014027	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1123863014028	Cl- selectivity filter; other site
1123863014029	Cl- binding residues [ion binding]; other site
1123863014030	pore gating glutamate residue; other site
1123863014031	dimer interface [polypeptide binding]; other site
1123863014032	H+/Cl- coupling transport residue; other site
1123863014033	glutaminase; Provisional; Region: PRK00971
1123863014034	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1123863014035	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
1123863014036	glycerate dehydrogenase; Provisional; Region: PRK06487
1123863014037	putative ligand binding site [chemical binding]; other site
1123863014038	putative NAD binding site [chemical binding]; other site
1123863014039	catalytic site [active]
1123863014040	Protein of unknown function (DUF2946); Region: DUF2946; pfam11162
1123863014041	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
1123863014042	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
1123863014043	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1123863014044	Helix-turn-helix domain; Region: HTH_17; pfam12728
1123863014045	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; cl17398
1123863014046	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1123863014047	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1123863014048	substrate binding pocket [chemical binding]; other site
1123863014049	chain length determination region; other site
1123863014050	substrate-Mg2+ binding site; other site
1123863014051	catalytic residues [active]
1123863014052	aspartate-rich region 1; other site
1123863014053	active site lid residues [active]
1123863014054	aspartate-rich region 2; other site
1123863014055	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1123863014056	glycosyltransferase, MGT family; Region: MGT; TIGR01426
1123863014057	active site
1123863014058	TDP-binding site; other site
1123863014059	acceptor substrate-binding pocket; other site
1123863014060	homodimer interface [polypeptide binding]; other site
1123863014061	Lycopene cyclase protein; Region: Lycopene_cycl; pfam05834
1123863014062	lycopene cyclase; Region: lycopene_cycl; TIGR01789
1123863014063	phytoene desaturase; Region: crtI_fam; TIGR02734
1123863014064	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1123863014065	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
1123863014066	active site lid residues [active]
1123863014067	substrate binding pocket [chemical binding]; other site
1123863014068	catalytic residues [active]
1123863014069	substrate-Mg2+ binding site; other site
1123863014070	aspartate-rich region 1; other site
1123863014071	aspartate-rich region 2; other site
1123863014072	beta-carotene hydroxylase; Region: PLN02601
1123863014073	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1123863014074	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1123863014075	putative NAD(P) binding site [chemical binding]; other site
1123863014076	putative substrate binding site [chemical binding]; other site
1123863014077	catalytic Zn binding site [ion binding]; other site
1123863014078	structural Zn binding site [ion binding]; other site
1123863014079	dimer interface [polypeptide binding]; other site
1123863014080	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
1123863014081	Thioredoxin; Region: Thioredoxin_4; cl17273
1123863014082	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1123863014083	SnoaL-like domain; Region: SnoaL_3; pfam13474
1123863014084	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1123863014085	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
1123863014086	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1123863014087	LysE type translocator; Region: LysE; cl00565
1123863014088	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1123863014089	Coenzyme A binding pocket [chemical binding]; other site
1123863014090	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1123863014091	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1123863014092	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1123863014093	ATP binding site [chemical binding]; other site
1123863014094	substrate interface [chemical binding]; other site
1123863014095	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1123863014096	active site residue [active]
1123863014097	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1123863014098	ThiS interaction site; other site
1123863014099	putative active site [active]
1123863014100	tetramer interface [polypeptide binding]; other site
1123863014101	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1123863014102	thiS-thiF/thiG interaction site; other site
1123863014103	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
1123863014104	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1123863014105	AzlC protein; Region: AzlC; cl00570
1123863014106	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1123863014107	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1123863014108	non-specific DNA binding site [nucleotide binding]; other site
1123863014109	salt bridge; other site
1123863014110	sequence-specific DNA binding site [nucleotide binding]; other site
1123863014111	Cupin domain; Region: Cupin_2; cl17218
1123863014112	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1123863014113	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863014114	Walker A/P-loop; other site
1123863014115	ATP binding site [chemical binding]; other site
1123863014116	Q-loop/lid; other site
1123863014117	ABC transporter signature motif; other site
1123863014118	Walker B; other site
1123863014119	D-loop; other site
1123863014120	H-loop/switch region; other site
1123863014121	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1123863014122	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1123863014123	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1123863014124	Walker A/P-loop; other site
1123863014125	ATP binding site [chemical binding]; other site
1123863014126	Q-loop/lid; other site
1123863014127	ABC transporter signature motif; other site
1123863014128	Walker B; other site
1123863014129	D-loop; other site
1123863014130	H-loop/switch region; other site
1123863014131	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1123863014132	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863014133	dimer interface [polypeptide binding]; other site
1123863014134	conserved gate region; other site
1123863014135	putative PBP binding loops; other site
1123863014136	ABC-ATPase subunit interface; other site
1123863014137	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1123863014138	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1123863014139	dimer interface [polypeptide binding]; other site
1123863014140	conserved gate region; other site
1123863014141	putative PBP binding loops; other site
1123863014142	ABC-ATPase subunit interface; other site
1123863014143	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1123863014144	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_3; cd08490
1123863014145	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1123863014146	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1123863014147	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1123863014148	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1123863014149	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1123863014150	NAD(P) binding site [chemical binding]; other site
1123863014151	catalytic residues [active]