-- dump date 20140619_231455 -- class Genbank::CDS -- table cds_note -- id note YP_913814.1 PFAM: conserved hypothetical protein 701; KEGG: sil:SPO3893 hypothetical protein YP_913815.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_913816.1 TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; KEGG: rde:RD1_0433 tRNA modification GTPase TrmE YP_913817.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_913818.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; KEGG: rde:RD1_0431 methyltransferase GidB YP_913819.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: sit:TM1040_2867 cobyrinic acid a,c-diamide synthase YP_913820.1 TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: rsp:RSP_1225 ParB-like partition protein YP_913821.1 PFAM: GrpE protein; KEGG: rsp:RSP_1219 chaperone protein GrpE (heat shock protein) YP_913822.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_913823.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_913824.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_913825.1 PFAM: Endoribonuclease L-PSP; KEGG: rsp:RSP_1223 translation initiation inhibitor, YjgF family / endoribonuclease L-PSP YP_913826.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_913827.1 PFAM: protein of unknown function DUF454; KEGG: atc:AGR_C_4462 hypothetical protein YP_913828.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_913829.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rsp:RSP_2576 alcohol dehydrogenase class III YP_913830.1 PFAM: peptidase S14, ClpP; KEGG: hne:HNE_0542 ATP-dependent Clp protease, proteolytic subunit ClpP YP_913831.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sus:Acid_2411 GCN5-related N-acetyltransferase YP_913832.1 PFAM: esterase; KEGG: sil:SPO3829 S-formylglutathione hydrolase YP_913833.1 PFAM: Pyrrolo-quinoline quinone; KEGG: rsp:RSP_2578 pqq dehydrogenase protein YP_913834.1 KEGG: sme:SMb20174 cytochrome c protein YP_913835.1 SMART: extracellular solute-binding protein, family 3; KEGG: rsp:RSP_2580 methanol oxidation protein YP_913836.1 KEGG: rsp:RSP_2581 rhodanese YP_913837.1 KEGG: rde:RD1_0896 hypothetical protein YP_913838.1 KEGG: rsp:RSP_2574 hypothetical protein YP_913839.1 KEGG: rsp:RSP_2582 hypothetical protein YP_913840.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; KEGG: rsp:RSP_2583 hypothetical protein YP_913841.1 KEGG: rsp:RSP_2584 hypothetical protein YP_913842.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2586 ABC multidrug efflux transporter, ATPase subunit YP_913843.1 PFAM: ABC-2 type transporter; KEGG: rsp:RSP_2587 ABC multidrug efflux transporter, inner membrane subunit YP_913844.1 KEGG: rsp:RSP_2588 hypothetical protein YP_913845.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: sit:TM1040_3754 molybdopterin-guanine dinucleotide biosynthesis protein A YP_913846.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sit:TM1040_3658 binding-protein-dependent transport systems inner membrane component YP_913847.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPO0052 ABC transporter, ATP-binding protein YP_913848.1 PFAM: TENA/THI-4 domain protein; KEGG: rde:RD1_3613 transcriptional regulator YP_913849.1 KEGG: sit:TM1040_3655 NlpA lipoprotein YP_913850.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sit:TM1040_3654 UBA/ThiF-type NAD/FAD binding fold YP_913851.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_913852.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_913853.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: bmb:BruAb1_0211 thiamine biosynthesis ThiS YP_913854.1 PFAM: FAD dependent oxidoreductase; KEGG: rde:RD1_0747 thiamine biosynthesis oxidoreductase ThiO YP_913855.1 KEGG: sil:SPO0045 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1 YP_913856.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpa:RPA4047 haloacid dehalogenase-like hydrolase YP_913857.1 KEGG: sit:TM1040_3505 conserved hypothetical protein YP_913858.1 KEGG: bja:bll6386 3-dehydroquinate dehydratase; TIGRFAM: 3-dehydroquinate dehydratase, type II; PFAM: dehydroquinase, class II YP_913859.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rsp:RSP_2281 two-component trancriptional regulator, winged helix family YP_913860.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; KEGG: rsp:RSP_2280 PAS sensor hybrid histidine kinase YP_913861.1 PFAM: AMP-dependent synthetase and ligase; KEGG: rsp:RSP_2279 long chain acyl-CoA synthetase YP_913862.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sit:TM1040_0114 ABC transporter related YP_913863.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_2277 ABC branched amino acid transporter family, inner membrane subunit YP_913864.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_2276 ABC branched amino acid transporter family, inner membrane subunit YP_913865.1 KEGG: rsp:RSP_2275 ABC branched amino acid transporter family, periplasmic substrate-binding subunit YP_913866.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2274 ABC branched amino acid transporter family, ATPase subunit YP_913867.1 KEGG: sil:SPO3289 phenylacetate-CoA ligase YP_913868.1 PFAM: ribosomal protein L36; KEGG: hne:HNE_3350 ribosomal protein L36 YP_913869.1 PFAM: N-formylglutamate amidohydrolase; KEGG: rde:RD1_0718 N-formylglutamate amidohydrolase YP_913870.1 PFAM: band 7 protein; KEGG: rsp:RSP_1401 band 7 protein YP_913871.1 PFAM: NUDIX hydrolase; KEGG: sil:SPO3279 NUDIX domain protein YP_913872.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: bpe:BP1270 glutathione S-transferase YP_913873.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_913874.1 KEGG: mmr:Mmar10_0746 hypothetical protein YP_913875.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: sit:TM1040_0130 ATPase AAA-2 YP_913876.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_913877.1 PFAM: Ferric reductase domain protein transmembrane component, N-terminal domain; KEGG: sit:TM1040_0134 ferric reductase-like transmembrane component-like YP_913879.1 KEGG: bhe:BH15450 hypothetical protein YP_913880.1 PFAM: IS66 Orf2 family protein; KEGG: sme:SMa1613 hypothetical protein YP_913881.1 PFAM: transposase IS66; KEGG: sme:SMa2171 hypothetical protein YP_913882.1 KEGG: sme:SMa1608 hypothetical protein YP_913883.1 KEGG: nma:NMA2178 hypothetical protein YP_913885.1 PFAM: CHAD domain containing protein; KEGG: neu:NE1494 hypothetical protein YP_913886.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: neu:NE1495 ParA family ATPase YP_913887.1 PFAM: adenylate cyclase; KEGG: neu:NE1496 hypothetical protein YP_913888.1 KEGG: jan:Jann_1003 hypothetical protein YP_913890.1 KEGG: gox:GOX2729 transposase YP_913891.1 KEGG: gox:GOX2722 truncated transposase YP_913892.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: nar:Saro_0441 two component transcriptional regulator, winged helix family YP_913893.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: ccr:CC0026 sensory box histidine kinase/response regulator YP_913894.1 PFAM: regulatory protein, LuxR; KEGG: sil:SPO1388 transcriptional regulator, LuxR family/hydrolase, alpha/beta fold family YP_913897.1 KEGG: rso:RSc2496 hypothetical signal peptide protein YP_913900.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: aeh:Mlg_2324 acylneuraminate cytidylyltransferase YP_913901.1 KEGG: ccr:CC2854 flagellin modification protein FlmD YP_913902.1 KEGG: dvu:DVU1387 hypothetical protein YP_913903.1 KEGG: eca:ECA3144 hypothetical protein YP_913906.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: son:SO3271 polysaccharide biosynthesis protein YP_913907.1 KEGG: nha:Nham_3939 transposase IS116/IS110/IS902 YP_913908.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: bpm:BURPS1710b_2170 DNA invertase YP_913909.1 KEGG: bmb:BruAb1_1581 hypothetical protein YP_913911.1 PFAM: Conjugal transfer TraD family protein; KEGG: rpc:RPC_4518 conjugal transfer TraD YP_913912.1 KEGG: rpe:RPE_3258 hypothetical protein YP_913913.1 MobA/MobL family protein YP_913915.1 PFAM: Prophage CP4-57 regulatory; KEGG: rpe:RPE_3260 phage transcriptional regulator, AlpA YP_913916.1 KEGG: rru:Rru_A1415 protein of unknown function DUF132 YP_913917.1 KEGG: sus:Acid_1920 conserved hypothetical protein YP_913918.1 PFAM: Resolvase, N-terminal domain; Recombinase; KEGG: nwi:Nwi_2841 resolvase YP_913919.1 PFAM: Resolvase, N-terminal domain; Recombinase; KEGG: nha:Nham_3864 recombinase YP_913921.1 PFAM: aldo/keto reductase; KEGG: rsp:RSP_3201 oxidoreductase YP_913922.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: rsp:RSP_3202 transcriptional regulator, AraC family YP_913925.1 KEGG: mmc:Mmcs_3174 hypothetical protein YP_913926.1 SMART: TIR protein; KEGG: bmb:BruAb1_0274 hypothetical protein YP_913927.1 PFAM: SH3, type 3 domain protein; KEGG: rsp:RSP_6161 hypothetical protein YP_913928.1 TIGRFAM: yecA family protein; PFAM: SEC-C motif domain protein; KEGG: rpe:RPE_2282 YecA family protein YP_913929.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: atc:AGR_L_286 chloramphenicol acetyltransferase YP_913931.1 KEGG: bcl:ABC1987 hypothetical protein YP_913932.1 KEGG: mes:Meso_3831 hypothetical protein YP_913933.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: nha:Nham_0569 DNA methylase N-4/N-6 YP_913935.1 PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_L_1711 acetyltransferase YP_913936.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: nha:Nham_4669 single-strand binding protein YP_913940.1 KEGG: mes:Meso_3838 hypothetical protein YP_913942.1 KEGG: nwi:Nwi_0844 hypothetical protein YP_913943.1 PFAM: helix-turn-helix domain protein; KEGG: mlo:msr6108 transcriptional regulator YP_913944.1 KEGG: nwi:Nwi_0845 hypothetical protein YP_913945.1 KEGG: nwi:Nwi_0846 possible replication protein A YP_913946.1 KEGG: mes:Meso_2334 hypothetical protein YP_913947.1 PFAM: C-5 cytosine-specific DNA methylase; transposase IS116/IS110/IS902 family protein; KEGG: mlo:mll5964 transposase YP_913949.1 PFAM: protein of unknown function DUF736; KEGG: mes:Meso_3845 conjugal transfer protein precursor YP_913950.1 PFAM: Lytic transglycosylase, catalytic; KEGG: mes:Meso_0517 lytic transglycosylase, catalytic YP_913952.1 KEGG: bja:bll0044 hypothetical protein YP_913953.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: rru:Rru_A0090 prevent-host-death protein YP_913954.1 KEGG: rru:Rru_A0091 PilT protein-like YP_913955.1 type IV secretion VirD4 coupling protein family YP_913956.1 KEGG: bja:bll0042 hypothetical protein YP_913957.1 PFAM: plasmid stabilization system; KEGG: sme:SMb20627 hypothetical protein YP_913958.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: sme:SMb20628 hypothetical protein YP_913959.1 KEGG: mes:Meso_0499 hypothetical protein YP_913960.1 PFAM: conjugation TrbI family protein; KEGG: mes:Meso_0500 conjugation TrbI-like protein YP_913961.1 PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: mes:Meso_0501 conjugal transfer protein TrbG/VirB9/CagX YP_913962.1 PFAM: Conjugal transfer protein; KEGG: mes:Meso_0502 conjugal transfer protein YP_913963.1 type IV secretion VirB6 family YP_913964.1 KEGG: mes:Meso_2319 hypothetical protein YP_913965.1 KEGG: mes:Meso_3855 conjugal transfer protein TrbJ YP_913966.1 type IV secretion system VirB4 family YP_913967.1 KEGG: mes:Meso_0507 conjugal transfer protein TrbB YP_913968.1 PFAM: Conjugal transfer protein TrbC; KEGG: mes:Meso_2323 conjugal transfer protein TrbC YP_913969.1 PFAM: type II secretion system protein E; KEGG: mes:Meso_2324 type II secretion system protein E YP_913970.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: nwi:Nwi_0252 transcriptional regulatory protein, LysR family YP_913971.1 KEGG: mlo:mlr6069 transposase YP_913973.1 PFAM: acriflavin resistance protein; KEGG: atc:AGR_L_494 RND pump protein YP_913974.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: atc:AGR_L_492 nodulation protein NolF YP_913975.1 PFAM: MltA-interacting MipA family protein; KEGG: ccr:CC0351 outer membrane protein YP_913977.1 PFAM: regulatory protein, TetR; KEGG: sco:SCO1193 TetR-family transcriptional regulator YP_913978.1 SMART: regulatory protein, ArsR; KEGG: nwi:Nwi_3123 transcriptional regulatory protein, ArsR family YP_913979.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: mes:Meso_3565 cupin 2, conserved barrel YP_913980.1 KEGG: mes:Meso_3566 hypothetical protein YP_913981.1 PFAM: regulatory proteins, IclR; KEGG: dar:Daro_0384 regulatory proteins, IclR YP_913982.1 PFAM: thioesterase superfamily protein; KEGG: gka:GK1990 4-hydroxybenzoyl-CoA thioesterase YP_913983.1 PFAM: monooxygenase, FAD-binding; KEGG: bja:blr0106 probable monooxygenase YP_913984.1 TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase; KEGG: bja:blr0107 probable coenzyme A ligase YP_913985.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rme:Rmet_4907 fumarylacetoacetate (FAA) hydrolase YP_913986.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; KEGG: mlo:mlr1135 maleylacetoacetate isomerase YP_913987.1 KEGG: bja:blr1052 ABC transporter binding protein YP_913988.1 PFAM: inner-membrane translocator; KEGG: bja:blr1064 ABC transporter permease protein YP_913989.1 PFAM: inner-membrane translocator; KEGG: bja:blr1065 ABC transporter permease protein YP_913990.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bja:blr1066 ABC transporter ATP-binding protein YP_913991.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bja:blr1067 ABC transporter ATP-binding protein YP_913992.1 PFAM: aldehyde dehydrogenase; KEGG: mlo:mll7197 dehydrogenase YP_913993.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: xcv:XCV2149 choline dehydrogenase YP_913994.1 KEGG: rme:Rmet_3785 beta-lactamase-like protein YP_913995.1 catalyzes the oxidative deamination of D-amino acids YP_913996.1 KEGG: oih:OB0952 hypothetical protein YP_913997.1 KEGG: oih:OB0951 hypothetical protein YP_913998.1 KEGG: bja:blr5691 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_913999.1 PFAM: regulatory protein, MarR; KEGG: sil:SPO1261 transcriptional regulator, MarR family YP_914000.1 PFAM: regulatory proteins, IclR; KEGG: bps:BPSS2127 IclR transcriptional regulator protein YP_914001.1 PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rpe:RPE_1982 TRAP C4-dicarboxylate transport system permease DctM subunit YP_914002.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: mlo:mll5171 hypothetical protein YP_914003.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cme:CMP184C hypothetical protein, conserved Pfam: Glyoxalase YP_914004.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: tma:TM1724 3-oxoacyl-(acyl carrier protein) reductase YP_914005.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: mlo:mlr5166 periplasmic mannitol-binding protein; SmoM YP_914006.1 KEGG: bxe:Bxe_C0656 hypothetical protein YP_914007.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rpa:RPA4557 hypothetical protein YP_914008.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: psp:PSPPH_1258 3-oxoacyl-(acyl-carrier-protein) reductase YP_914009.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_914010.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: mag:amb2599 acyl-CoA dehydrogenase YP_914011.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: jan:Jann_0676 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_914012.1 PFAM: flavin reductase domain protein, FMN-binding; KEGG: bte:BTH_II2298 flavin reductase domain protein YP_914013.1 PFAM: luciferase family protein; KEGG: jan:Jann_2939 luciferase-like YP_914014.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; KEGG: mta:Moth_0917 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_914016.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: pau:PA14_10280 short-chain dehydrogenase YP_914017.1 PFAM: alpha/beta hydrolase fold; KEGG: rso:RS05450 hydrolase signal peptide protein YP_914018.1 PFAM: 4-oxalocrotonate tautomerase; KEGG: rso:RS05436 hypothetical protein YP_914019.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: psb:Psyr_2945 regulatory protein, LysR:LysR, substrate-binding YP_914020.1 KEGG: rso:RS05437 hypothetical protein YP_914021.1 PFAM: regulatory protein, MerR; KEGG: rsp:RSP_1790 probable transcriptional regulator YP_914022.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: rsp:RSP_1791 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_914023.1 KEGG: tfu:Tfu_1571 hypothetical protein YP_914024.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: sal:Sala_2405 arsenical-resistance protein YP_914025.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: rpa:RPA3554 arsenate reductase YP_914026.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: nwi:Nwi_3124 low molecular weight phosphotyrosine protein phosphatase YP_914027.1 SMART: regulatory protein, ArsR; KEGG: nwi:Nwi_3123 transcriptional regulatory protein, ArsR family YP_914028.1 PFAM: regulatory protein, LysR; KEGG: gvi:glr3360 LysR family transcriptional regulatory protein YP_914029.1 KEGG: ttj:TTHB244 phenol hydroxylase component B YP_914030.1 PFAM: luciferase family protein; KEGG: jan:Jann_2939 luciferase-like YP_914031.1 KEGG: bxe:Bxe_C0656 hypothetical protein YP_914032.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pol:Bpro_5571 L-carnitine dehydratase/bile acid-inducible protein F YP_914033.1 PFAM: aldehyde dehydrogenase; KEGG: bmb:BruAb2_0802 aldehyde dehydrogenase family protein YP_914034.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: aeh:Mlg_2736 GAF modulated sigma54 specific transcriptional regulator, fis family YP_914035.1 PFAM: flavin reductase domain protein, FMN-binding; KEGG: rsp:RSP_3957 flavoprotein oxidoreductase YP_914036.1 PFAM: luciferase family protein; KEGG: ppu:PP_3171 hypothetical protein YP_914038.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sus:Acid_5864 xylose isomerase domain protein TIM barrel YP_914039.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sus:Acid_5864 xylose isomerase domain protein TIM barrel YP_914040.1 PFAM: luciferase family protein; KEGG: psb:Psyr_1559 luciferase YP_914041.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bcn:Bcen_1980 transcriptional regulator, LysR family YP_914042.1 PFAM: regulatory protein, TetR; KEGG: pae:PA3678 probable transcriptional regulator YP_914043.1 KEGG: gme:Gmet_2060 fusaric acid resistance protein conserved region YP_914044.1 KEGG: xcb:XC_0382 b-ketoadipate enol-lactone hydrolase YP_914045.1 KEGG: rfr:Rfer_0981 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_914046.1 KEGG: rme:Rmet_5091 oligopeptide/dipeptide ABC transporter, ATP-binding protein-like protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_914047.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: psp:PSPPH_2784 dipeptide transport system permease protein DppC AGR_L_321 YP_914048.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ppu:PP_4455 opine ABC transporter, periplasmic binding protein YP_914049.1 PFAM: extracellular solute-binding protein, family 5; KEGG: pol:Bpro_4344 extracellular solute-binding protein, family 5 YP_914050.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: mes:Meso_4461 transcriptional regulator, GntR family YP_914051.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: mes:Meso_4453 malate/L-lactate dehydrogenase YP_914052.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: rpc:RPC_0105 alcohol dehydrogenase YP_914053.1 PFAM: aldehyde dehydrogenase; KEGG: mes:Meso_4451 aldehyde dehydrogenase YP_914054.1 PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein; KEGG: pat:Patl_0897 mandelate racemase/muconate lactonizing enzyme-like YP_914055.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: reu:Reut_A0050 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_914056.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: msu:MS0202 hypothetical protein YP_914057.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: msu:MS0201 RbsB protein YP_914058.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: msu:MS0200 MglA protein YP_914059.1 PFAM: inner-membrane translocator; KEGG: msu:MS0199 ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_914060.1 involved in rpiB and als operon repression YP_914061.1 PFAM: PfkB domain protein; KEGG: msu:MS0197 RbsK protein YP_914062.1 KEGG: gox:GOX2677 transposase (class I) YP_914067.1 KEGG: nfa:nfa39970 hypothetical protein YP_914071.1 PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: ypm:YP_1932 methyltransferase YP_914072.1 KEGG: mes:Meso_0232 hypothetical protein YP_914073.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: bte:BTH_II1364 DNA methyltransferase YP_914074.1 KEGG: sme:SMc00822 hypothetical protein YP_914075.1 KEGG: sit:TM1040_0815 transcriptional regulator, XRE family YP_914077.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: eli:ELI_07940 bacteriophage-acquired protein YP_914079.1 KEGG: sil:SPO2726 hypothetical protein YP_914080.1 KEGG: nwi:Nwi_0792 gene transfer agent (GTA) like protein YP_914081.1 TIGRFAM: phage cell wall peptidase, NlpC/P60 family; PFAM: NLP/P60 protein; KEGG: sil:SPO2729 hypothetical protein YP_914082.1 KEGG: rpb:RPB_3460 phage conserved hypothetical protein BR0599 YP_914083.1 KEGG: mmr:Mmar10_0930 hypothetical protein YP_914084.1 KEGG: dvu:DVU1490 tail tape measure protein YP_914086.1 KEGG: bmb:BruAb2_0879 hypothetical sugar-binding protein YP_914087.1 PFAM: ChaC family protein; KEGG: mlo:mll2256 cation transport protein YP_914088.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: rxy:Rxyl_2255 general substrate transporter YP_914089.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: ret:RHE_PF00188 transcriptional regulator protein, GntR family YP_914090.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20427 amino acid ABC transporter ATP-binding protein YP_914091.1 PFAM: extracellular solute-binding protein, family 3; KEGG: mlo:mlr7133 amino acid ABC transporter protein, solute-binding component YP_914092.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20429 amino acid ABC transporter permease protein YP_914093.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20430 amino acid ABC transporter permease protein YP_914094.1 PFAM: Asp/Glu racemase; KEGG: sme:SMb20431 hypothetical arylmalonate decarboxylase protein YP_914095.1 catalyzes the formation of 2-oxobutanoate from L-threonine; involved in ectoine utilization YP_914096.1 cyclodeaminase YP_914097.1 PFAM: peptidase M24; KEGG: sme:SMb20434 hydrolasepeptidase protein YP_914098.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: sme:SMb20435 hypothetical protein YP_914099.1 PFAM: aldehyde dehydrogenase; KEGG: sil:SPO1137 succinate-semialdehyde dehydrogenase YP_914100.1 PFAM: aminotransferase class-III; KEGG: sit:TM1040_2691 aminotransferase class-III YP_914101.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: csa:Csal_2340 alcohol dehydrogenase, zinc-binding YP_914102.1 PFAM: protein of unknown function DUF1006; KEGG: jan:Jann_2912 protein of unknown function DUF1006 YP_914104.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sil:SPO1617 type I secretion target repeat protein YP_914105.1 KEGG: rsp:RSP_3055 transcriptional regulator, MarR family YP_914106.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rsp:RSP_3056 TonB dependent-iron siderophore receptor YP_914107.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_C_4492 ferrichrome ABC transporter (ATP-binding protein) YP_914108.1 PFAM: transport system permease protein; KEGG: atc:AGR_C_4491 ferrichrome ABC transporter (permease) homolog YP_914109.1 PFAM: transport system permease protein; KEGG: atc:AGR_C_4489 ferrichrome ABC transporter (permease) YP_914110.1 PFAM: periplasmic binding protein; KEGG: atc:AGR_C_4488 unknown conserved protein YP_914111.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; L-seryl-tRNA selenium transferase; KEGG: pen:PSEEN0568 selenocysteine synthase (with SelD) YP_914112.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sme:SMa1782 LysR-family transcriptional regulator YP_914113.1 PFAM: transmembrane pair domain protein; KEGG: sme:SMa1780 hypothetical protein YP_914114.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mlo:mll4929 transcriptional regulator YP_914116.1 PFAM: protein of unknown function DUF112, transmembrane; KEGG: sme:SMb20726 conserved hypothetical membrane protein YP_914117.1 KEGG: atc:AGR_C_4484 tricarboxylic transport membrane protein YP_914118.1 PFAM: Uncharacterized protein UPF0065; KEGG: sme:SMb20724 tricarboxylic transport membrane protein YP_914119.1 KEGG: atc:AGR_C_4480 periplasmic iron-binding protein YP_914120.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sme:SMb20722 two-component response regulator protein YP_914121.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Two-component sensor kinase N-terminal domain protein; KEGG: ret:RHE_CH03588 probable two-component sensor histidine kinase protein YP_914122.1 PFAM: protein of unknown function DUF475; KEGG: rsp:RSP_0459 hypothetical protein YP_914123.1 KEGG: sil:SPO0845 hypothetical protein YP_914124.1 PFAM: AmiS/UreI transporter; KEGG: bpa:BPP1188 transporter protein YP_914125.1 PFAM: oxidoreductase domain protein; dihydrodipicolinate reductase; NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; homoserine dehydrogenase, NAD-binding; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; KEGG: sil:SPO0852 oxidoreductase, Gfo/Idh/MocA family YP_914126.1 PFAM: glycosyl transferase, family 2; KEGG: sil:SPO0853 glycosyl transferase, group 2 family protein YP_914127.1 PFAM: CBS domain containing protein; HPP family protein+B94; KEGG: rsp:RSP_0830 CBS-domain-containing membrane protein YP_914128.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: psb:Psyr_0495 regulatory protein, GntR:bacterial regulatory protein, GntR YP_914129.1 KEGG: atc:AGR_L_1874 hypothetical protein YP_914130.1 PFAM: LamB/YcsF family protein; KEGG: pst:PSPTO_5378 LamB/YcsF family protein YP_914131.1 PFAM: protein of unknown function DUF1445; KEGG: atc:AGR_L_1868 hypothetical protein YP_914132.1 PFAM: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; KEGG: atc:AGR_L_1866 hypothetical protein YP_914133.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: atc:AGR_L_1864 biotin carboxylase protein A2 YP_914134.1 PFAM: ammonia monooxygenase; KEGG: jan:Jann_2088 ammonia monooxygenase YP_914135.1 PFAM: protein of unknown function DUF886; KEGG: mlo:mlr8324 hypothetical protein YP_914136.1 PFAM: luciferase family protein; KEGG: mlo:mll2315 alkanal monooxygenase (bacterial liciferase alpha chain) like protein YP_914137.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pau:PA14_48770 transcriptional regulator YP_914138.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01961 hypothetical protein YP_914139.1 KEGG: bja:blr6753 hypothetical protein YP_914140.1 PFAM: NADPH-dependent FMN reductase; KEGG: mlo:mll2599 probable reductase YP_914141.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc01956 hypothetical protein YP_914142.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bpa:BPP2935 glutathione S-transferase YP_914143.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_914144.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_914145.1 PFAM: phage integrase family protein; KEGG: gox:GOX2318 prophage integrase YP_914147.1 KEGG: rsp:RSP_3624 hypothetical protein YP_914149.1 KEGG: pst:PSPTO_3428 hypothetical protein YP_914151.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mes:Meso_1199 helicase-like YP_914152.1 KEGG: jan:Jann_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_914162.1 KEGG: sit:TM1040_1631 hypothetical protein YP_914163.1 TIGRFAM: phage/plasmid primase, P4 family; PFAM: Poxvirus D5 protein; KEGG: bld:BLi03629 hypothetical protein YP_914165.1 KEGG: rsp:RSP_3778 hypothetical protein YP_914166.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: rsp:RSP_2072 phage-related holin protein YP_914168.1 PFAM: Resolvase helix-turn-helix domain protein; KEGG: sit:TM1040_1626 hypothetical protein YP_914169.1 PFAM: phage Terminase; KEGG: rsp:RSP_2070 phage-related terminase YP_914170.1 TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein; KEGG: rsp:RSP_2069 phage portal protein, HK97 family YP_914171.1 PFAM: peptidase S14, ClpP; KEGG: rsp:RSP_2068 ClpP-like protease YP_914172.1 TIGRFAM: phage major capsid protein, HK97 family; KEGG: rsp:RSP_2067 prophage LambdaSo, major capsid protein, HK97 family YP_914175.1 KEGG: sit:TM1040_1619 phage conserved hypothetical protein, phiE125 gp8 YP_914176.1 TIGRFAM: phage head-tail adaptor YP_914182.1 KEGG: rsp:RSP_3791 hypothetical protein YP_914185.1 KEGG: mes:Meso_1234 hypothetical protein YP_914186.1 KEGG: nar:Saro_2739 hypothetical protein YP_914191.1 KEGG: syw:SYNW0477 hypothetical protein YP_914192.1 KEGG: rsp:RSP_6192 hypothetical protein YP_914195.1 PFAM: Resolvase, N-terminal domain; Recombinase; KEGG: nwi:Nwi_1951 resolvase YP_914196.1 PFAM: protein of unknown function DUF159; KEGG: sit:TM1040_1580 protein of unknown function DUF159 YP_914200.1 PFAM: protein of unknown function DUF983; KEGG: ccr:CC1021 hypothetical protein YP_914202.1 KEGG: jan:Jann_0243 hypothetical protein YP_914203.1 KEGG: bms:BR0799 hypothetical protein YP_914204.1 KEGG: rde:RD1_A0063 succinoglycan biosynthesis protein ExoI YP_914205.1 PFAM: diaminopimelate epimerase; KEGG: sil:SPO0278 diaminopimelate epimerase YP_914206.1 KEGG: rsp:RSP_0935 MiaB-like radical SAM protein; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB YP_914207.1 PFAM: histone deacetylase superfamily; KEGG: rsp:RSP_1137 histone deacetylase family protein YP_914208.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; KEGG: jan:Jann_0090 exodeoxyribonuclease VII, small subunit YP_914209.1 PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase YP_914210.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_914211.1 PFAM: SH3, type 3 domain protein; KEGG: sil:SPO0041 hypothetical protein YP_914212.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: jan:Jann_0273 NAD-dependent epimerase/dehydratase YP_914213.1 PFAM: luciferase family protein; KEGG: sil:SPO2518 bacterial luciferase family protein YP_914214.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_914215.1 PFAM: histone family protein DNA-binding protein; KEGG: rsp:RSP_1388 DNA-binding protein HU, form N YP_914216.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: rsp:RSP_1390 transporter, DMT superfamily YP_914217.1 KEGG: hne:HNE_1223 glutathione S-transferase YP_914218.1 PFAM: Helix-turn-helix, type 11 domain protein; KEGG: hne:HNE_1222 hypothetical protein YP_914219.1 PFAM: aminotransferase, class V; KEGG: ret:RHE_PE00221 hypothetical protein YP_914220.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: ret:RHE_PE00222 probable transcriptional regulator protein, AsnC family YP_914221.1 KEGG: ret:RHE_CH01163 exonuclease protein involved in mRNA processing YP_914222.1 PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: ccr:CC3610 DNA ligase, ATP-dependent YP_914223.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_0658 probable ATP-dependent helicase YP_914224.1 KEGG: rsp:RSP_0659 metallo-phosphoesterase YP_914225.1 KEGG: mlo:mll1390 outer membrane protein YP_914226.1 negatively supercoils closed circular double-stranded DNA YP_914227.1 PFAM: protein of unknown function DUF1491; KEGG: rsp:RSP_1677 hypothetical protein YP_914228.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_914229.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein; KEGG: rsp:RSP_1675 ribonuclease III YP_914230.1 KEGG: rsp:RSP_1674 type 1 signal peptidase; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_914231.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_914232.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_914233.1 KEGG: rsp:RSP_1779 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein YP_914234.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: rde:RD1_3403 TPR domain protein YP_914235.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: sil:SPO0316 electrotransfer ubiquinone oxidoreductase family protein YP_914236.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_914237.1 KEGG: sil:SPO0311 hypothetical protein YP_914238.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_0736 MobC protein YP_914239.1 PFAM: AzlC family protein; KEGG: rsp:RSP_0739 branched chain amino acid efflux pump, large (AzlC) subunit YP_914240.1 PFAM: branched-chain amino acid transport; KEGG: rde:RD1_3412 hypothetical protein YP_914241.1 KEGG: rsp:RSP_6127 hypothetical protein YP_914242.1 PFAM: aa3 type cytochrome c oxidase subunit IV; KEGG: rsp:RSP_6128 Aa3-type cytochrome c oxidase subunit IV YP_914243.1 PFAM: beta-lactamase domain protein; KEGG: rsp:RSP_0741 metallo-beta-lactamase family protein YP_914244.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: rsp:RSP_0742 probable acyl-CoA dehydrogenase YP_914245.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5 domain protein; SUA5/yciO/yrdC, N-terminal domain; KEGG: rsp:RSP_0743 translation factor YP_914246.1 PFAM: protein of unknown function DUF179; KEGG: sil:SPO0296 transcriptional regulator YP_914247.1 KEGG: rde:RD1_3420 hypothetical protein YP_914248.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: rsp:RSP_1001 DNA polymerase bacteriophage-type YP_914250.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_914251.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: rsp:RSP_0858 transporter, RhaT family, DMT superfamily YP_914253.1 PFAM: protein of unknown function DUF955; KEGG: gbe:GbCGDNIH1_1521 hypothetical protein YP_914254.1 KEGG: gbe:GbCGDNIH1_1520 hypothetical protein YP_914255.1 KEGG: sil:SPOA0122 ISSpo9, transposase YP_914256.1 PFAM: zinc finger, CHC2-family protein; KEGG: bpa:BPP0490 DNA primase YP_914257.1 KEGG: bpa:BPP0491 hypothetical protein YP_914258.1 KEGG: bpa:BPP0493 hypothetical protein YP_914259.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: ret:RHE_PE00402 probable polymerase epsilon subunit protein YP_914260.1 KEGG: bmb:BruAb2_0399 hypothetical protein YP_914261.1 KEGG: bmb:BruAb2_0400 hypothetical protein YP_914264.1 PFAM: helix-turn-helix domain protein; KEGG: rde:RD1_0810 DNA-binding protein YP_914266.1 KEGG: rpb:RPB_2539 hypothetical protein YP_914267.1 PFAM: Integrase, catalytic region; KEGG: bmb:BruAb1_0746 transposase, hypothetical YP_914268.1 KEGG: rde:RD1_0796 transposition protein YP_914269.1 KEGG: nha:Nham_2090 hypothetical protein YP_914270.1 PFAM: Integrase, catalytic region; KEGG: sme:SMc03282 transposase number 1 for insertion sequence ISRM27 YP_914271.1 PFAM: IstB domain protein ATP-binding protein; KEGG: sme:SMc03281 transposase YP_914272.1 PFAM: Recombinase; KEGG: rsp:RSP_3812 recombinase YP_914273.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_3955 transposase IS116/IS110/IS902 YP_914274.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: psb:Psyr_4615 spermidine/putrescine ABC transporter ATP-binding subunit YP_914275.1 KEGG: bmb:BruAb2_0855 hypothetical spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein YP_914276.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ppu:PP_0413 polyamine ABC transporter, permease protein YP_914277.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pst:PSPTO_0565 polyamine ABC transporter, permease protein YP_914278.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: pau:PA14_72890 transcriptional regulator YP_914279.1 PFAM: protein of unknown function DUF849; KEGG: bur:Bcep18194_C7701 protein of unknown function DUF849 YP_914280.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: reu:Reut_C6223 5-oxoprolinase (ATP-hydrolyzing) YP_914281.1 PFAM: Hydantoinase B/oxoprolinase; KEGG: reu:Reut_C6222 hydantoinase B/oxoprolinase YP_914282.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_914284.1 PFAM: thioesterase superfamily protein; KEGG: bja:blr1345 hypothetical protein YP_914285.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: bur:Bcep18194_B1227 transcriptional regulator, XRE family with cupin sensor domain YP_914286.1 PFAM: protein of unknown function DUF1100, hydrolase family protein; KEGG: ppu:PP_3195 hypothetical protein YP_914287.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: reu:Reut_C6224 short-chain dehydrogenase/reductase SDR YP_914288.1 PFAM: major facilitator superfamily MFS_1; KEGG: rha:RHA1_ro04907 transporter, MFS superfamily YP_914289.1 KEGG: gbe:GbCGDNIH1_1799 transposase YP_914290.1 PFAM: SpoVT/AbrB domain protein; KEGG: sme:SMc03949 nitrogen regulatory protein YP_914291.1 PFAM: PilT protein domain protein; SMART: Nucleotide binding protein, PINc; KEGG: sme:SMa0981 probable NtrR2 transcription regulator YP_914292.1 KEGG: eba:ebB86 RelE-like cytotoxic translational repressor of toxin-antitoxin stability system YP_914293.1 KEGG: noc:Noc_2738 transcriptional regulator, XRE family YP_914294.1 KEGG: sme:SMc01416 hypothetical protein YP_914296.1 PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: rsp:RSP_1146 glutamine-pyruvate aminotransferase YP_914297.1 KEGG: rsp:RSP_1148 hypothetical protein YP_914298.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_914299.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_914300.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; KEGG: sit:TM1040_2820 3-beta hydroxysteroid dehydrogenase/isomerase YP_914301.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: ter:Tery_1077 glucose-methanol-choline oxidoreductase YP_914302.1 PFAM: NUDIX hydrolase; KEGG: rsp:RSP_1208 NUDIX hydrolase YP_914303.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: rde:RD1_0413 response regulator YP_914304.1 PFAM: Hpt domain protein; KEGG: sit:TM1040_2886 Hpt protein YP_914305.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_914307.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_914308.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: nwi:Nwi_0688 3-demethylubiquinone-9 3-methyltransferase YP_914309.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: bmb:BruAb2_0726 MogA, molybdenum cofactor biosynthesis protein YP_914310.1 KEGG: rsp:RSP_0986 hypothetical protein YP_914311.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02169 ATP-binding ABC transporter protein YP_914312.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_0989 ABC sugar transporter, inner membrane subunit YP_914313.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rsp:RSP_0990 ABC sugar transporter, periplasmic sugar binding subunit YP_914314.1 PFAM: ROK family protein; regulatory protein, MarR; KEGG: rsp:RSP_0991 transcriptional regulator, ROK family YP_914315.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: sme:SMa0116 DnaJ/CbpA-type protein YP_914316.1 KEGG: rru:Rru_A2016 hypothetical protein YP_914317.1 PFAM: protein of unknown function DUF1289; KEGG: jan:Jann_2180 protein of unknown function DUF1289 YP_914318.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_914319.1 KEGG: rsp:RSP_2685 cytochrome c-type biogenesis protein, CycH YP_914320.1 TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 sarcosine oxidase beta subunit YP_914321.1 KEGG: rsp:RSP_1403 conserved hypoothetical protein YP_914322.1 PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 sarcosine oxidase delta subunit protein YP_914323.1 TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: rsp:RSP_2689 sarcosine oxidase, alpha subunit YP_914324.1 PFAM: Sarcosine oxidase, gamma subunit; KEGG: rsp:RSP_2690 sarcosine oxidase gamma subunit YP_914325.1 KEGG: rde:RD1_1770 hypothetical protein YP_914326.1 PFAM: manganese and iron superoxide dismutase; KEGG: rsp:RSP_2693 superoxide dismutase, Fe-Mn family YP_914327.1 PFAM: protein of unknown function DUF461; KEGG: rde:RD1_1682 hypothetical protein YP_914328.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: rsp:RSP_3601 lipolytic enzyme, G-D-S-L family YP_914329.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sil:SPO0794 copper-translocating P-type ATPase YP_914330.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: mes:Meso_4112 ErfK/YbiS/YcfS/YnhG YP_914331.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_914332.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_914333.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_2208 ABC sugar transporter, inner membrane subunit YP_914334.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_2209 ABC sugar transporter, inner membrane subunit YP_914335.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPO0378 sugar ABC transporter, ATP-binding protein YP_914336.1 PFAM: basic membrane lipoprotein; KEGG: rsp:RSP_2211 ABC transporter, periplasmic substrate-binding protein YP_914337.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_2212 acetyltransferase YP_914338.1 PFAM: peptidase M22, glycoprotease; KEGG: rsp:RSP_2213 hypothetical protein YP_914339.1 PFAM: nitrogen-fixing NifU domain protein; KEGG: sit:TM1040_3091 nitrogen-fixing NifU-like YP_914340.1 PFAM: UspA domain protein; KEGG: sit:TM1040_3730 UspA YP_914341.1 PFAM: sugar transferase; KEGG: rsp:RSP_1189 sugar transferase YP_914342.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_914343.1 KEGG: sil:SPO2985 hypothetical protein YP_914344.1 PFAM: cation transporter; KEGG: rsp:RSP_1854 potassium uptake transporter, transmembrane component, TrkH YP_914345.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: rsp:RSP_1855 hypothetical protein YP_914346.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_914347.1 KEGG: sit:TM1040_2311 conserved hypothetical protein YP_914348.1 KEGG: rsp:RSP_1858 glycyl-tRNA synthetase beta subunit YP_914349.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_914350.1 PFAM: cell wall hydrolase, SleB; KEGG: rsp:RSP_1860 hypothetical protein YP_914351.1 PFAM: dihydroneopterin aldolase; KEGG: rsp:RSP_1861 probable dihydroneopterin aldolase YP_914352.1 KEGG: rsp:RSP_1862 dihydropteroate synthase, DhpS; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_914353.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_914354.1 PFAM: monooxygenase, FAD-binding; KEGG: rsp:RSP_2656 salicylate hydroxylase (salicylate 1-monooxygenase) YP_914355.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type; KEGG: rsp:RSP_2654 DnaK suppressor protein, DksA family YP_914356.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: rsp:RSP_2653 ATPase, AAA family YP_914357.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rde:RD1_2794 acetyltransferase YP_914358.1 PFAM: Lytic transglycosylase, catalytic; KEGG: sil:SPO2284 transglycosylase SLT domain protein YP_914359.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sil:SPO0340 2-oxoglutarate dehydrogenase, E3 component, dihydrolipoamide dehydrogenase YP_914360.1 KEGG: jan:Jann_0835 inner membrane protein YP_914362.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_914363.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_914366.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: rsp:RSP_0966 succinyl-CoA synthetase, alpha subunit YP_914367.1 catalyzes the interconversion of succinyl-CoA and succinate YP_914368.1 PFAM: Hemolysin-type calcium-binding region; KEGG: pol:Bpro_4929 hemolysin-type calcium-binding region YP_914369.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_914370.1 PFAM: protein of unknown function DUF81; KEGG: rsp:RSP_0969 integral membrane protein YP_914371.1 PFAM: HpcH/HpaI aldolase; KEGG: rsp:RSP_0970 citrate lyase beta chain YP_914372.1 PFAM: NnrUfamily protein; KEGG: jan:Jann_0815 NnrU YP_914373.1 KEGG: sil:SPO0354 hypothetical protein YP_914374.1 PFAM: MaoC domain protein dehydratase; KEGG: sil:SPO0355 hypothetical protein YP_914375.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: rsp:RSP_0974 succinate dehydrogenase cytochrome b-556 subunit YP_914376.1 KEGG: rsp:RSP_0975 succinate dehydrogenase, hydrophobic membrane anchor protein YP_914377.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_914378.1 KEGG: jan:Jann_0807 hypothetical protein YP_914379.1 KEGG: rsp:RSP_0978 hypothetical protein YP_914380.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_914381.1 KEGG: rde:RD1_1633 hypothetical protein YP_914382.1 PFAM: beta-lactamase domain protein; KEGG: rsp:RSP_2268 metallo beta lactamase superfamily YP_914383.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_914384.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_914385.1 KEGG: rsp:RSP_2271 hypothetical protein YP_914386.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: rsp:RSP_2272 N-acetylmuramoyl-L-alanine amidase, family 2 YP_914387.1 PFAM: protein of unknown function DUF519; KEGG: sil:SPO0421 hypothetical protein YP_914388.1 PFAM: protein of unknown function DUF1127; KEGG: sit:TM1040_2023 protein of unknown function DUF1127 YP_914389.1 KEGG: rsp:RSP_2093 Mrp (multidrug resistance-associated proteins) family protein YP_914390.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_914391.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: rsp:RSP_6038 methyltransferase MraW/YabC YP_914392.1 KEGG: sil:SPO1180 hypothetical protein YP_914393.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2 YP_914394.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_914395.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: sil:SPO1183 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_914396.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_914397.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_914398.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: rsp:RSP_0007 outer membrane protein YP_914399.1 KEGG: rsp:RSP_2869 possible tellurite resistance protein YP_914400.1 KEGG: rsp:RSP_2868 inosine-5'-monophosphate dehydrogenase; TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain containing protein; IMP dehydrogenase/GMP reductase YP_914401.1 KEGG: rsp:RSP_1319 possible invasion protein YP_914402.1 PFAM: Fmu (Sun) domain protein; KEGG: rsp:RSP_0455 possible NOL1/NOP2/sun family protein YP_914403.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; KEGG: sit:TM1040_1228 multi-sensor hybrid histidine kinase YP_914404.1 KEGG: rsp:RSP_0453 hypothetical protein YP_914405.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_914406.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_914407.1 PFAM: protein of unknown function DUF1330; KEGG: rsp:RSP_0450 hypothetical protein YP_914408.1 KEGG: rsp:RSP_0449 glutamine amidotransferase YP_914411.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_914412.1 KEGG: sil:SPO1317 hypothetical protein YP_914413.1 TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic region; KEGG: rde:RD1_1915 thiamine pyrophosphokinase YP_914414.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sil:SPO2816 peptide/nickel/opine uptake family ABC transporter, permease protein YP_914415.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sil:SPO2815 peptide/nickel/opine uptake family ABC transporter, permease protein YP_914416.1 PFAM: extracellular solute-binding protein, family 5; KEGG: sil:SPO2814 peptide/opine/nickel uptake family ABC transporter, periplasmic substrate-binding protein YP_914417.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; KEGG: sil:SPO2813 peptide/nickel/opine uptake family ABC transporter, ATP-binding protein YP_914418.1 KEGG: sit:TM1040_0719 peptidase M20D, amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_914419.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_914420.1 PFAM: protein of unknown function DUF924; KEGG: sil:SPO2224 hypothetical protein YP_914421.1 PFAM: major facilitator superfamily MFS_1; KEGG: rsp:RSP_2970 transporter, major facilitator superfamily (MFS) YP_914422.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_914423.1 KEGG: sit:TM1040_2200 bacterioferritin-associated ferredoxin YP_914424.1 TIGRFAM: bacterioferritin; PFAM: Rubrerythrin; Ferritin, Dps family protein; KEGG: rsp:RSP_3342 bacterioferritin YP_914425.1 KEGG: rsp:RSP_2504 phosphoglycolate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_914426.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_914427.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_914428.1 PFAM: peptidase S58, DmpA; KEGG: sit:TM1040_2667 peptidase S58, DmpA YP_914429.1 KEGG: rpa:RPA4834 peptide methionine sulfoxide reductase; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_914430.1 PFAM: methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 11; KEGG: sit:TM1040_2376 ribosomal L11 methyltransferase YP_914431.1 PFAM: protein of unknown function DUF1127; KEGG: sit:TM1040_2374 protein of unknown function DUF1127 YP_914432.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_914433.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_914434.1 PFAM: OmpA/MotB domain protein; KEGG: rde:RD1_4081 OmpA domain protein YP_914435.1 KEGG: rsp:RSP_1011 hypothetical protein YP_914438.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_914439.1 PFAM: Rhodanese domain protein; KEGG: rsp:RSP_0885 thiosulfate sulfurtransferase, rhodanese-like YP_914440.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_914441.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit YP_914442.1 PFAM: phosphate transporter; KEGG: rsp:RSP_2170 phosphate transporter, Pit family YP_914443.1 PFAM: NUDIX hydrolase; KEGG: sit:TM1040_0668 NUDIX hydrolase YP_914444.1 PFAM: Class I peptide chain release factor; KEGG: rsp:RSP_1366 hypothetical protein YP_914445.1 TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; Penicillin-binding domain protein; KEGG: sil:SPO0135 penicillin-binding protein 1C YP_914446.1 PFAM: conserved hypothetical protein 1620; KEGG: sil:SPO3140 hypothetical protein YP_914447.1 PFAM: protein of unknown function DUF463, YcjX family protein; KEGG: sil:SPO3142 hypothetical protein YP_914448.1 KEGG: rsp:RSP_2013 DEAD/DEAH box helicase; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_914449.1 KEGG: bpe:BP1216 hypothetical protein YP_914450.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: rsp:RSP_0875 methionyl-tRNA formyl transferase YP_914451.1 KEGG: mmr:Mmar10_2929 dienelactone hydrolase YP_914452.1 KEGG: sit:TM1040_1832 conserved hypothetical protein YP_914453.1 TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase; KEGG: rsp:RSP_0874 formylmethionine deformylase YP_914454.1 PFAM: formylmethionine deformylase; KEGG: rsp:RSP_0872 formylmethionine deformylase YP_914455.1 KEGG: rsp:RSP_0872 formylmethionine deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_914456.1 PFAM: aminotransferase, class I and II; KEGG: rsp:RSP_0871 aminotransferase YP_914457.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sat:SYN_02183 protein ErfK YP_914458.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: rsp:RSP_0764 multi antimicrobial extrusion (MATE) family efflux pump NorM YP_914459.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: rsp:RSP_0958 RAM domain protein YP_914460.1 catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate YP_914461.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: rde:RD1_2963 glutamate uptake regulatory protein YP_914462.1 KEGG: rsp:RSP_1943 hypothetical protein YP_914463.1 PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: rsp:RSP_1942 sulfite/nitrite reductase hemoprotein subunit YP_914464.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_914465.1 KEGG: rsp:RSP_1940 hypothetical protein YP_914466.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: rsp:RSP_1939 NADPH-ferredoxin reductase YP_914467.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_914468.1 KEGG: rru:Rru_A0385 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_914469.1 PFAM: protein of unknown function DUF488; KEGG: rfr:Rfer_4130 protein of unknown function DUF488 YP_914470.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sme:SMc04263 amino acid carrier transmembrane protein YP_914471.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: bmb:BruAb1_1197 hypothetical membrane protein YP_914472.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: bmb:BruAb1_1199 outer membrane protein, hypothetical YP_914473.1 PFAM: phosphate transporter; KEGG: sit:TM1040_0608 phosphate transporter YP_914474.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: cjk:jk0467 Na+/alanine symporter YP_914476.1 PFAM: regulatory protein, TetR; KEGG: sit:TM1040_1583 transcriptional regulator, TetR family YP_914477.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: pfl:PFL_6132 3-oxoacyl-(acyl-carrier-protein) synthase III YP_914478.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; KEGG: pfl:PFL_6133 3-beta hydroxysteroid dehydrogenase/isomerase family protein YP_914479.1 PFAM: beta-lactamase domain protein; KEGG: pfl:PFL_6134 metallo-beta-lactamase protein YP_914480.1 TIGRFAM: adenylate-forming enzyme; KEGG: pfl:PFL_6135 PF5220 YP_914481.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20290 transcriptional regulator protein YP_914482.1 PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease; KEGG: sme:SMb20289 permease protein YP_914483.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sme:SMb20288 hypothetical protein YP_914484.1 PFAM: protein of unknown function DUF81; KEGG: sme:SMb20287 hypothetical protein YP_914485.1 KEGG: sme:SMc04361 hydantoin racemase protein YP_914486.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin; KEGG: pcr:Pcryo_0405 permease for cytosine/purines, uracil, thiamine, allantoin YP_914487.1 PFAM: Asp/Glu racemase; KEGG: pcr:Pcryo_0404 Asp/Glu racemase YP_914488.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: pcr:Pcryo_0403 transcriptional regulator, GntR family YP_914489.1 KEGG: rsp:RSP_6118 hypothetical protein YP_914490.1 TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: rsp:RSP_0673 thioesterase YP_914491.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sil:SPO3112 proton transporter TolQ YP_914492.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sil:SPO3111 biopolymer transport protein, ExbD/TolR family YP_914493.1 PFAM: TolA family protein; KEGG: rsp:RSP_0670 possible TolA protein YP_914494.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_914495.1 TIGRFAM: OmpA domain protein; PFAM: OmpA/MotB domain protein; KEGG: jan:Jann_0976 OmpA/MotB YP_914496.1 KEGG: rsp:RSP_0667 hypothetical protein YP_914497.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: rsp:RSP_0666 probable cell cycle protein YP_914498.1 KEGG: rsp:RSP_0665 FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_914499.1 PFAM: Chorismate mutase; KEGG: rsp:RSP_0662 chorismate mutase YP_914500.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: rde:RD1_2106 hypothetical protein YP_914501.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_914502.1 PFAM: peptidase M48, Ste24p; KEGG: rsp:RSP_0554 heat shock protein HtpX YP_914503.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_914504.1 TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; KEGG: rsp:RSP_0556 Holliday junction resolvase YP_914505.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_914506.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_914507.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_914508.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_914509.1 PFAM: multiple resistance and pH regulation protein F; KEGG: jan:Jann_3719 multiple resistance and pH regulation protein F YP_914510.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: jan:Jann_3720 Na+/H+ antiporter subunit YP_914512.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_914513.1 PFAM: Lytic transglycosylase, catalytic; KEGG: rsp:RSP_0881 soluble lytic transglycosylase YP_914514.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: jan:Jann_0141 protein of unknown function DUF6, transmembrane YP_914515.1 PFAM: inositol monophosphatase; KEGG: rsp:RSP_2169 inositol monophosphatase family protein YP_914516.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: sil:SPO1369 transcriptional regulator, GntR family YP_914517.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_914518.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_914519.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_914520.1 PFAM: N-formylglutamate amidohydrolase; KEGG: bme:BMEII0366 formiminoglutamase YP_914521.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rde:RD1_3680 CaiB/BaiF family protein YP_914522.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: rde:RD1_3681 acyl-CoA dehydrogenase YP_914523.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_914524.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; KEGG: rru:Rru_A1295 extracellular solute-binding protein, family 3 YP_914525.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rru:Rru_A1296 amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine YP_914526.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rru:Rru_A1297 amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine YP_914527.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rru:Rru_A1298 ABC transporter component YP_914528.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: mes:Meso_1173 NADH:flavin oxidoreductase/NADH oxidase YP_914529.1 PFAM: Patatin; KEGG: rpa:RPA4207 patatin-like phospholipase domain YP_914531.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: atc:AGR_L_2203 TlyC; hemolysin YP_914532.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mlo:mll6938 transcriptional regulator YP_914533.1 TIGRFAM: TonB family protein; KEGG: rpb:RPB_1657 TonB-like protein YP_914534.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: atc:AGR_C_265 biopolymer transport ExbD protein YP_914535.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: atc:AGR_C_264 biopolymer transport ExbB protein YP_914536.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: rsp:RSP_3678 siderophore-interacting protein YP_914537.1 PFAM: aminotransferase, class V; KEGG: rsp:RSP_0245 serine-pyruvate aminotransferase/aspartate aminotransferase YP_914538.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_0246 ABC lipid efflux transporter, fused ATPase and inner membrane subunits YP_914539.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: sit:TM1040_1985 glycine cleavage T protein (aminomethyl transferase) YP_914540.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: sme:SMa2355 DNA polymerase IV YP_914541.1 KEGG: jan:Jann_1800 hypothetical protein YP_914542.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_914543.1 PFAM: dienelactone hydrolase; KEGG: mmr:Mmar10_2526 carboxymethylenebutenolidase YP_914544.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bja:blr0519 hypothetical protein YP_914545.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: sme:SMc04046 hypothetical protein YP_914546.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: rsp:RSP_1706 acetyltransferase YP_914547.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bme:BMEI0471 ABC transporter ATP-binding protein YP_914548.1 KEGG: jan:Jann_3368 hypothetical protein YP_914549.1 TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; KEGG: sit:TM1040_0226 SecE subunit of protein translocation complex YP_914550.1 KEGG: rsp:RSP_1704 probable transcription antitermination protein NusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_914551.1 binds directly to 23S ribosomal RNA YP_914552.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_914553.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_914554.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_914555.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_914557.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_914559.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: rsp:RSP_1711 possible transporter, RhaT family, DMT superfamily YP_914560.1 KEGG: jan:Jann_0574 hypothetical protein YP_914561.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_914562.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_914563.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_914564.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_914566.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_914567.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_914568.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_914569.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_914570.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_914571.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_914572.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_914573.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_914574.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_914575.1 PFAM: ribosomal protein L29; KEGG: jan:Jann_0599 ribosomal protein L29 YP_914576.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_914577.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_914578.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_914579.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_914580.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_914581.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_914582.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_914583.1 binds 5S rRNA along with protein L5 and L25 YP_914584.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_914585.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_914586.1 KEGG: rsp:RSP_2084 hypothetical protein YP_914587.1 late assembly protein YP_914588.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_914589.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_914590.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_914591.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_914592.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_914593.1 is a component of the macrolide binding site in the peptidyl transferase center YP_914594.1 PFAM: regulatory protein, LuxR; Autoinducer-binding domain protein; KEGG: jan:Jann_0619 transcriptional regulator, LuxR family YP_914595.1 KEGG: jan:Jann_0620 N-acyl-L-homoserine lactone synthetase-like YP_914596.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: rsp:RSP_1743 ATPase, AAA family YP_914597.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: rsp:RSP_1744 CrcB-like protein YP_914598.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: rsp:RSP_1745 pseudouridine synthase YP_914599.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sil:SPO0517 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_914600.1 PFAM: ATP12 ATPase; KEGG: jan:Jann_0626 ATP12 ATPase YP_914601.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; SMART: extracellular solute-binding protein, family 3; KEGG: rsp:RSP_1747 ABC glutamate/glutamine/aspartate/asparagine transporter, periplasmic substrate-binding protein YP_914602.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_1748 ABC glutamate/glutamine/aspartate/asparagine transporter, inner membrane subunit BztB YP_914603.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_1749 ABC glutamate/glutamine/aspartate/asparagine transporter, inner membrane subunit BztC YP_914604.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPO0522 glutamate/glutamine/aspartate/asparagine ABC transporter, ATP-binding protein YP_914605.1 KEGG: rde:RD1_B0053 rhizobiocin YP_914606.1 PFAM: aminotransferase, class IV; KEGG: rsp:RSP_1768 aminotransferase class IV , D-alanine aminotransferase YP_914607.1 PFAM: HpcH/HpaI aldolase; KEGG: rde:RD1_1001 citrate lyase, beta subunit YP_914608.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; KEGG: sil:SPO0098 peptide/opine/nickel uptake family ABC transporter, ATP-binding protein YP_914609.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sil:SPO0099 peptide/opine/nickel uptake family ABC transporter, permease protein YP_914610.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sit:TM1040_3436 binding-protein-dependent transport systems inner membrane component YP_914611.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1; KEGG: bms:BRA0311 transporter YP_914612.1 catalyzes the oxidative deamination of D-amino acids YP_914613.1 PFAM: Transglycosylase-associated protein; KEGG: bur:Bcep18194_B2685 transglycosylase-associated protein YP_914615.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rsp:RSP_1754 hypothetical protein YP_914616.1 KEGG: tpa:TP0470 hypothetical protein YP_914617.1 PFAM: Lytic transglycosylase, catalytic; KEGG: sme:SMc01230 transglycosylase transmembrane protein YP_914618.1 PFAM: extracellular solute-binding protein, family 5; KEGG: jan:Jann_0782 extracellular solute-binding protein, family 5 YP_914619.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: rsp:RSP_0565 phosphatidylcholine synthase YP_914620.1 KEGG: sil:SPO3353 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_914621.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_914622.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_914623.1 PFAM: metallophosphoesterase; KEGG: rsp:RSP_1353 protein phosphatase YP_914624.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; PFAM: Na+/Pi-cotransporter; KEGG: ret:RHE_CH03044 probable sodium-dependent phosphate transporter protein YP_914625.1 PFAM: CreA family protein; KEGG: rsp:RSP_2505 possible CreA protein YP_914626.1 TIGRFAM: hemimethylated DNA binding protein; KEGG: rsp:RSP_1498 hypothetical protein YP_914627.1 KEGG: jan:Jann_4052 anti-sigma regulatory factor (serine/threonine protein kinase) YP_914628.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rsp:RSP_1501 antisigma-factor antagonist (STAS) domain protein YP_914630.1 PFAM: Hemolysin-type calcium-binding region; peptidase M10A and M12B, matrixin and adamalysin; peptidase domain protein; SMART: peptidase, metallopeptidases; KEGG: rsp:RSP_0230 neutral zinc metallopeptidase YP_914631.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: rsp:RSP_2415 hypothetical protein YP_914632.1 PFAM: protein of unknown function DUF403; KEGG: rsp:RSP_2416 hypothetical protein YP_914633.1 PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein; KEGG: rsp:RSP_2417 hypothetical protein YP_914634.1 PFAM: 20S proteasome, A and B subunits; KEGG: rsp:RSP_2420 proteasome-type protease YP_914635.1 This protein performs the mismatch recognition step during the DNA repair process YP_914636.1 KEGG: sit:TM1040_2771 hydratase/decarboxylase YP_914637.1 PFAM: extracellular solute-binding protein, family 1; KEGG: rsp:RSP_0346 ABC transporter, substrate binding protein YP_914638.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0347 ABC transporter, inner membrane subunit YP_914639.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_C_3893 probable ABC transport system permease YP_914640.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_0349 ABC transporter, ATPase subunit YP_914641.1 PFAM: Hemolysin-type calcium-binding region; KEGG: bja:bll7673 hypothetical protein YP_914642.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: sil:SPO0851 glycosyl transferase, WecB/TagA/CpsF family YP_914643.1 KEGG: sit:TM1040_2399 membrane protein YP_914644.1 PFAM: beta-ketoacyl synthase; Thioesterase; acyl transferase domain protein; NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; phosphopantetheine-binding; KR; KEGG: sil:SPO0849 non-ribosomal peptide synthase YP_914645.1 PFAM: glycosyl transferase, family 2; KEGG: sil:SPO0848 glycosyl transferase, group 2 family protein YP_914646.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; formyl transferase domain protein; phosphopantetheine-binding; luciferase family protein; KEGG: sil:SPO0847 non-ribosomal peptide synthetase YP_914647.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: sma:SAV1748 phosphopantetheinyl transferase YP_914648.1 PFAM: glycosyl transferase, group 1; KEGG: sil:SPO0842 glycosyl transferase, group 1 family protein YP_914650.1 PFAM: sugar transferase; KEGG: jan:Jann_4237 undecaprenyl-phosphate galactosephosphotransferase YP_914651.1 KEGG: sil:SPO0844 hypothetical protein YP_914652.1 PFAM: glycosyl transferase, family 2; KEGG: sil:SPO0843 glycosyl transferase, group 2 family protein YP_914653.1 KEGG: sil:SPO0839 exopolysaccharide biosynthesis domain protein YP_914654.1 PFAM: lipopolysaccharide biosynthesis; KEGG: pen:PSEEN2947 exopolysaccharide transport protein YP_914655.1 PFAM: polysaccharide biosynthesis protein; KEGG: sil:SPO0841 polysaccharide biosynthesis protein YP_914656.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_914657.1 KEGG: rsp:RSP_2718 possible outer membrane protein YP_914658.1 PFAM: Rhodanese domain protein; KEGG: sil:SPO0091 rhodanese-like domain protein YP_914659.1 PFAM: isochorismatase hydrolase; KEGG: rde:RD1_0585 pyrazinamidase/nicotinamidase YP_914660.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_914661.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_914662.1 PFAM: MORN repeat-containing protein; KEGG: rsp:RSP_2332 hypothetical protein YP_914663.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_914664.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: rde:RD1_3200 threonine efflux protein YP_914665.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_914666.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: sil:SPO2141 pyridoxamine 5''-phosphate oxidase YP_914667.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: rsp:RSP_2346 cold-shock DNA-binding domain protein YP_914668.1 PFAM: protein of unknown function DUF192; KEGG: sil:SPO2139 hypothetical protein YP_914669.1 KEGG: rsp:RSP_1849 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein YP_914670.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: jan:Jann_3205 PTSINtr with GAF domain, PtsP YP_914671.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rpd:RPD_2478 ABC transporter related YP_914672.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: rpd:RPD_2479 transport system permease protein YP_914673.1 PFAM: periplasmic binding protein; KEGG: rpa:RPA0151 possible iron ABC transporter periplasmic binding protein YP_914674.1 PFAM: protein of unknown function UPF0066; KEGG: bja:bll5136 VirR YP_914676.1 KEGG: sit:TM1040_2053 conserved hypothetical protein YP_914678.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_1056 periplasmic sensor signal transduction histidine kinase YP_914679.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_914680.1 TIGRFAM: ribonuclease P protein component; PFAM: ribonuclease P protein; KEGG: rsp:RSP_1060 ribonuclease P protein component YP_914681.1 PFAM: protein of unknown function DUF37; KEGG: rsp:RSP_1061 hypothetical protein YP_914682.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_914683.1 PFAM: EAL domain protein; KEGG: rde:RD1_1456 EAL domain protein YP_914684.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_914685.1 PFAM: MOSC domain containing protein; KEGG: rsp:RSP_1065 hypothetical protein YP_914686.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_914687.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_914688.1 PFAM: Phosphoglycerate mutase; KEGG: rsp:RSP_1070 hypothetical protein YP_914689.1 PFAM: PfkB domain protein; KEGG: rsp:RSP_2334 carbohydrate kinase, PfkB YP_914690.1 PFAM: protein of unknown function DUF1025; KEGG: jan:Jann_3637 protein of unknown function DUF1025 YP_914691.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_914694.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_914695.1 KEGG: afm:Afu1g11690 hypothetical protein YP_914696.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_914697.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_914698.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_914699.1 PFAM: YceI family protein; KEGG: sil:SPO2279 hypothetical protein YP_914700.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: sil:SPO0330 cytochrome c peroxidase YP_914701.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_914702.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: rsp:RSP_2906 methylase YP_914703.1 KEGG: rsp:RSP_6078 hypothetical protein YP_914704.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_914705.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_914706.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: rsp:RSP_2903 probable PpiC-type peptidyl-prolyl cis-trans isomerase YP_914707.1 PFAM: Organic solvent tolerance protein; KEGG: rsp:RSP_2902 organic solvent tolerance protein YP_914708.1 PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2901 permease YP_914709.1 PFAM: permease YjgP/YjgQ family protein; KEGG: rsp:RSP_2900 predicted permease YP_914710.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_914711.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_914712.1 KEGG: sit:TM1040_0952 conserved hypothetical protein YP_914713.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: rsp:RSP_2896 multiple antibiotic transporter YP_914714.1 PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: rde:RD1_3255 twin-arginine translocation protein, TatA/E family YP_914715.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: rsp:RSP_6059 twin-arginine translocation system protein, TatB YP_914716.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: rsp:RSP_2541 twin-arginine translocation system protein, TatC YP_914717.1 PFAM: protein of unknown function DUF815; KEGG: rsp:RSP_2542 ATPase YP_914718.1 PFAM: Choloylglycine hydrolase; KEGG: atc:AGR_L_573 probable hydrolase VCA0877 YP_914720.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_914721.1 PFAM: regulatory protein, MarR; KEGG: rde:RD1_3650 transcriptional regulator MarR/EmrR family YP_914722.1 PFAM: Entericidin EcnAB YP_914723.1 KEGG: rde:RD1_1084 hypothetical protein YP_914724.1 PFAM: Entericidin EcnAB; KEGG: rsp:RSP_6220 hypothetical protein YP_914725.1 PFAM: alpha/beta hydrolase fold; Thioesterase; PGAP1 family protein; KEGG: rsp:RSP_0821 esterase/lipase/thioesterase YP_914726.1 KEGG: rsp:RSP_0822 hypothetical protein YP_914727.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_914728.1 catalyzes the phosphorylation of NAD to NADP YP_914729.1 TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: rsp:RSP_2537 probable peptide chain release factor RF3 YP_914731.1 PFAM: OsmC family protein; KEGG: rpa:RPA4194 osmotically inducible protein OsmC YP_914732.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: bmb:BruAb2_0942 hypothetical membrane protein YP_914733.1 PFAM: protein of unknown function DUF305; KEGG: mes:Meso_3895 protein of unknown function DUF305 YP_914734.1 KEGG: rsp:RSP_2659 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_914735.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: jan:Jann_1504 HesB/YadR/YfhF YP_914736.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rsp:RSP_2657 exodeoxyribonuclease III YP_914738.1 PFAM: extracellular solute-binding protein, family 5; KEGG: rsp:RSP_2856 oligopeptide ABC transporter, periplasmic-binding protein YP_914739.1 TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: rde:RD1_2738 D-beta-hydroxybutyrate dehydrogenase YP_914740.1 PFAM: basic membrane lipoprotein; KEGG: rha:RHA1_ro04986 hypothetical protein YP_914741.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_914742.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rde:RD1_1872 lactoylglutathione lyase YP_914743.1 PFAM: regulatory protein, MarR; KEGG: sil:SPO1267 transcriptional regulator, MarR family YP_914744.1 PFAM: protein of unknown function DUF339; KEGG: rsp:RSP_0761 hypothetical protein YP_914745.1 PFAM: aminotransferase, class I and II; KEGG: rsp:RSP_0763 aspartate aminotransferase YP_914746.1 catalyzes the formation of fumarate from aspartate YP_914747.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sil:SPO2668 transcriptional regulator, LysR family YP_914748.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: atc:AGR_L_410 probable L-malate dehydrogenase YP_914749.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: jan:Jann_3495 transcriptional regulator, AsnC family YP_914750.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain YP_914751.1 KEGG: rsp:RSP_3680 transcriptional regulator, TetR family YP_914752.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc02378 periplasmic binding transmembrane protein YP_914753.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02379 permease protein YP_914754.1 KEGG: ret:RHE_PF00412 probable amino acid ABC transporter, ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_914755.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: csa:Csal_2827 acyl-CoA dehydrogenase-like protein YP_914756.1 PFAM: DNA/RNA non-specific endonuclease; KEGG: rha:RHA1_ro05345 hypothetical protein YP_914757.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: bha:BH0684 prepro-alkaline protease YP_914758.1 TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit, N terminal domain protein; KEGG: rsp:RSP_3547 ribonucleotide reductase YP_914759.1 PFAM: DSBA oxidoreductase; KEGG: rsp:RSP_2852 predicted polyketide biosynthesis associated protein YP_914760.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sil:SPO2069 benzoate-coenzyme A ligase YP_914761.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: rsp:RSP_0386 cold-shock DNA-binding domain protein YP_914762.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_914763.1 KEGG: sit:TM1040_1720 conserved hypothetical protein YP_914764.1 TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein; KEGG: rde:RD1_1887 polyhydroxyalkanoate depolymerase, intracellular YP_914765.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: rde:RD1_1888 poly(3-hydroxyalkanoate) polymerase YP_914766.1 KEGG: rsp:RSP_0381 hypothetical protein YP_914767.1 TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR; PFAM: PHB accumulation regulatory domain protein; PHA accumulation regulator DNA-binding protein; KEGG: rsp:RSP_0380 hypothetical protein YP_914768.1 PFAM: phage integrase family protein; KEGG: rsp:RSP_1662 integrase/recombinase YP_914769.1 KEGG: rsp:RSP_6015 hypothetical protein YP_914770.1 KEGG: rsp:RSP_3624 hypothetical protein YP_914774.1 KEGG: ecc:c1524 hypothetical protein YP_914775.1 KEGG: bxe:Bxe_A3103 bacteriophage hypothetical protein YP_914776.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mes:Meso_1199 helicase-like YP_914777.1 KEGG: jan:Jann_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_914782.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B; KEGG: rsp:RSP_3771 hypothetical protein YP_914788.1 KEGG: sit:TM1040_1631 hypothetical protein YP_914790.1 TIGRFAM: phage/plasmid primase, P4 family; PFAM: Poxvirus D5 protein; KEGG: lin:lin2587 similar to bacteriophage protein YP_914791.1 KEGG: rsp:RSP_3778 hypothetical protein YP_914792.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: rsp:RSP_2072 phage-related holin protein YP_914794.1 PFAM: Resolvase helix-turn-helix domain protein; KEGG: sit:TM1040_1626 hypothetical protein YP_914795.1 PFAM: phage Terminase; KEGG: rsp:RSP_2070 phage-related terminase YP_914796.1 TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein; KEGG: rsp:RSP_2069 phage portal protein, HK97 family YP_914797.1 PFAM: peptidase S14, ClpP; KEGG: rsp:RSP_2068 ClpP-like protease YP_914798.1 TIGRFAM: phage major capsid protein, HK97 family; KEGG: rsp:RSP_2067 prophage LambdaSo, major capsid protein, HK97 family YP_914801.1 KEGG: sit:TM1040_1619 phage conserved hypothetical protein, phiE125 gp8 YP_914802.1 KEGG: sit:TM1040_1666 conserved hypothetical protein YP_914803.1 KEGG: rpa:RPA1898 homologue of rhodobacter capsulatus gene transfer agent (GTA) orfg8 (32% identity) YP_914804.1 TIGRFAM: phage protein, HK97 gp10 family; PFAM: TP901-1 ORF40 family protein; KEGG: mes:Meso_1888 phage protein, HK97 GP10 family YP_914807.1 TIGRFAM: phage tape measure protein; KEGG: rso:RSc0873 bacteriophage-related transmembrane protein YP_914810.1 KEGG: mes:Meso_1234 hypothetical protein YP_914811.1 KEGG: nar:Saro_2739 hypothetical protein YP_914813.1 PFAM: transposase, IS4 family protein; KEGG: sit:TM1040_0174 transposase, IS4 YP_914814.1 KEGG: nar:Saro_2759 transposase orfA IS5 family element YP_914815.1 KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase YP_914816.1 PFAM: conserved hypothetical protein 698; KEGG: rsp:RSP_4010 conserved hypothetical protein 698 YP_914817.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_914818.1 PFAM: major facilitator superfamily MFS_1; KEGG: bja:bll6038 hypothetical transport protein YP_914819.1 PFAM: AMP-dependent synthetase and ligase; KEGG: rde:RD1_2917 hypothetical protein YP_914820.1 KEGG: jan:Jann_1566 aldehyde dehydrogenase YP_914821.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rde:RD1_2923 transcriptional regulator, LacI family YP_914822.1 KEGG: ccr:CC2592 ISCc1, transposase OrfB YP_914824.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_3955 transposase IS116/IS110/IS902 YP_914825.1 PFAM: creatinase; peptidase M24; KEGG: ppu:PP_3667 creatinase YP_914826.1 PFAM: Creatininase; KEGG: rxy:Rxyl_0459 creatininase YP_914827.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rde:RD1_2370 transcriptional regulator, LysR family YP_914828.1 KEGG: rde:RD1_2369 spermidine/putrescine ABC transporter, periplasmic binding protein YP_914829.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_2368 putrescine ABC transporter, permease protein YP_914830.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_2367 spermidine/putrescine transport system, permease protein YP_914831.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rde:RD1_2364 spermidine/putrescine ABC transporter, ATP-binding protein YP_914832.1 PFAM: extracellular solute-binding protein, family 3; KEGG: atc:AGR_L_407 probable binding protein component of ABC transporter YP_914833.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20264 amino acid ABC transporter permease protein YP_914834.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pau:PA14_47950 amino acid ABC transporter permease YP_914835.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20266 amino acid ABC transporter ATP-binding protein YP_914837.1 PFAM: major facilitator superfamily MFS_1; KEGG: rru:Rru_A1180 major facilitator superfamily MFS_1 YP_914838.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: mes:Meso_3754 glucose-methanol-choline oxidoreductase YP_914839.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rha:RHA1_ro00226 ABC sugar transporter, periplasmic solute-binding protein YP_914840.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sco:SCO6010 probable ABC-transport system ATP binding protein YP_914841.1 PFAM: inner-membrane translocator; KEGG: tfu:Tfu_1920 ABC transporter transmembrane transport protein YP_914842.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bms:BR1086 transcriptional regulator, LysR family YP_914843.1 PFAM: amidohydrolase 2; KEGG: mlo:mll5767 hypothetical protein YP_914844.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: mes:Meso_4503 amidohydrolase YP_914845.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: mlo:mlr0545 hypothetical protein YP_914846.1 PFAM: NIPSNAP family containing protein; KEGG: bbr:BB1741 hypothetical protein YP_914847.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: bbr:BB1748 short chain dehydrogenase YP_914848.1 PFAM: aspartate dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: rso:RS01727 L-aspartate dehydrogenase YP_914849.1 PFAM: alpha/beta hydrolase fold; KEGG: bbr:BB1746 hydrolase YP_914850.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: bpa:BPP2288 hypothetical protein YP_914851.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: pfo:Pfl_5244 choline dehydrogenase YP_914852.1 PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase YP_914853.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sil:SPO0590 transcriptional regulator, LacI family YP_914854.1 PFAM: extracellular solute-binding protein, family 1; KEGG: rxy:Rxyl_0062 extracellular solute-binding protein, family 1 YP_914855.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bja:bll2730 probable ABC transporter permease protein YP_914856.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rfr:Rfer_0952 binding-protein-dependent transport systems inner membrane component YP_914857.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sth:STH1782 sugar ABC transportor ATP-binding protein YP_914858.1 PFAM: aldehyde dehydrogenase; KEGG: mlo:mll1015 aldehyde dehydrogenase YP_914859.1 PFAM: aldehyde dehydrogenase; KEGG: jan:Jann_3747 aldehyde dehydrogenase YP_914861.1 KEGG: nha:Nham_3600 AMP-dependent synthetase and ligase YP_914862.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_914863.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pau:PA14_32360 LysR-family transcriptional regulator YP_914865.1 KEGG: sil:SPO0875 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_914866.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: bja:blr6041 glycolate oxidase YP_914867.1 PFAM: flavin reductase domain protein, FMN-binding; KEGG: dar:Daro_1187 hypothetical protein YP_914868.1 KEGG: atc:AGR_L_3474 hypothetical protein YP_914869.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: eca:ECA3213 AraC-family transcriptional regulator YP_914870.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: eca:ECA3214 probable short chain dehydrogenase YP_914871.1 KEGG: atc:AGR_C_479 hypothetical protein YP_914872.1 PFAM: OsmC family protein; KEGG: gbe:GbCGDNIH1_0067 organic hydroperoxide resistance protein YP_914873.1 PFAM: regulatory protein, MarR; KEGG: mlo:mlr2690 probable transcriptional regulator YP_914874.1 KEGG: aba:Acid345_1171 hypothetical protein YP_914875.1 PFAM: regulatory proteins, IclR; KEGG: bja:bll3094 transcriptional regulatory protein YP_914876.1 PFAM: aminotransferase, class V; KEGG: bja:blr3095 probable aminotransferase YP_914877.1 PFAM: extracellular solute-binding protein, family 3; KEGG: bja:blr3096 ABC transporter substrate-binding protein YP_914878.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bja:blr3097 ABC transporter permease protein YP_914879.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bja:blr3098 ABC transporter permease protein YP_914880.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: psp:PSPPH_1133 amino acid ABC transporter, ATP-binding protein YP_914881.1 PFAM: protein of unknown function DUF1697; KEGG: bja:bll4334 hypothetical protein YP_914882.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mlo:mll3624 ATP-binding component of transport system YP_914883.1 PFAM: extracellular solute-binding protein, family 1; KEGG: sit:TM1040_0544 extracellular solute-binding protein, family 1 YP_914884.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mll3625 ABC transport system permease protein YP_914885.1 PFAM: beta-lactamase domain protein; KEGG: sit:TM1040_0541 beta-lactamase-like YP_914886.1 KEGG: sme:SMb20160 hypothetical protein YP_914888.1 PFAM: beta-lactamase; KEGG: rsp:RSP_2235 hypothetical protein YP_914889.1 KEGG: mes:Meso_0502 conjugal transfer protein YP_914890.1 PFAM: glucose-methanol-choline oxidoreductase; KEGG: mlo:mlr6655 similar to dehydrogenase subunit YP_914891.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: mlo:mlr6654 ABC transporter, ATP-binding component YP_914892.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr6653 ABC transporter (permease protein) YP_914893.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mlo:mlr6652 ABC transporter (permease protein) YP_914894.1 PFAM: extracellular solute-binding protein, family 1; KEGG: mlo:mlr6651 ABC transporter (substrate-binding protein) YP_914895.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_914896.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mlo:mlr6648 acetolactate synthase large subunit YP_914897.1 SMART: helix-turn-helix domain protein; KEGG: mlo:mlr6646 hypothetical protein YP_914898.1 KEGG: mlo:mll6647 hypothetical protein YP_914899.1 PFAM: fumarate lyase; KEGG: bms:BR1958 aspartate ammonia-lyase YP_914900.1 PFAM: glycoside hydrolase, family 3 domain protein; KEGG: bcn:Bcen_1514 glycoside hydrolase, family 3-like YP_914901.1 KEGG: mlo:mlr6657 hypothetical protein YP_914902.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase; KEGG: mlo:mlr6656 dehydrogenase YP_914903.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: bcn:Bcen_1508 xylose isomerase-like TIM barrel YP_914904.1 PFAM: major facilitator superfamily MFS_1; KEGG: rha:RHA1_ro01579 possible transporter, MFS superfamily YP_914905.1 KEGG: sme:SMb20276 transcriptional regulator protein YP_914906.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: gvi:glr2986 LysR family transcriptional regulatory protein YP_914907.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ppu:PP_2411 major facilitator family transporter YP_914908.1 PFAM: 4-vinyl reductase, 4VR; KEGG: reu:Reut_B4820 4-vinyl reductase, 4VR YP_914909.1 PFAM: peptidase M19, renal dipeptidase; KEGG: cps:CPS_4019 peptidase, M19 family YP_914910.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sil:SPO1912 transcriptional regulator, GntR family YP_914911.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pol:Bpro_2634 alcohol dehydrogenase, zinc-binding YP_914912.1 activates fatty acids by binding to coenzyme A YP_914913.1 KEGG: mes:Meso_2537 rhodanese-like YP_914914.1 PFAM: protein of unknown function DUF1330; KEGG: mes:Meso_0684 protein of unknown function DUF1330 YP_914915.1 TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines, uracil, thiamine, allantoin; KEGG: sit:TM1040_0338 NCS1 nucleoside transporter family YP_914916.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_914917.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_914918.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis along with cofH YP_914919.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cps:CPS_4048 conserved hypothetical protein TIGR00423 YP_914920.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) YP_914921.1 PFAM: protein of unknown function DUF121; KEGG: cps:CPS_4046 hypothetical protein YP_914922.1 TIGRFAM: F420-dependent oxidoreductase, PFAM: protein of unknown function DUF129; KEGG: cps:CPS_4045 F420-dependent oxidoreductase YP_914923.1 TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: cps:CPS_4044 NADPH-dependent F420 reductase YP_914924.1 PFAM: luciferase family protein; KEGG: cps:CPS_4043 methylenetetrahydromethanopterin reductase YP_914925.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional regulator YcdC, C-terminal domain protein; KEGG: mlo:mlr1634 probable transcriptional regulator YP_914926.1 PFAM: protein of unknown function DUF336; KEGG: atc:AGR_C_2067 hypothetical protein YP_914927.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: atc:AGR_C_2066 hypothetical protein YP_914928.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: atc:AGR_C_2063 hypothetical protein YP_914929.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: rsp:RSP_3275 MoxR-like ATPase YP_914930.1 KEGG: rsp:RSP_3276 hypothetical protein YP_914931.1 KEGG: rsp:RSP_6252 hypothetical protein YP_914932.1 PFAM: von Willebrand factor, type A; KEGG: rsp:RSP_3278 Von Willebrand domain containing protein YP_914933.1 PFAM: von Willebrand factor, type A; KEGG: rsp:RSP_3280 hypothetical protein YP_914934.1 KEGG: rsp:RSP_3281 hypothetical protein YP_914935.1 KEGG: rsp:RSP_3282 hypothetical protein YP_914936.1 KEGG: mes:Meso_3101 PRC-barrel YP_914937.1 KEGG: rsp:RSP_2379 hypothetical protein YP_914938.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: ret:RHE_PE00299 oxidoreductase protein, short-chain dehydrogenase reductase (SDR)family YP_914939.1 KEGG: sme:SMb20339 hypothetical protein YP_914940.1 PFAM: protein of unknown function DUF892; KEGG: sme:SMc00371 hypothetical protein YP_914941.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: rsp:RSP_2681 sigma factor, RpoE YP_914942.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: sme:SMc01610 transcription regulator protein YP_914943.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rsp:RSP_1440 TonB dependent, hydroxamate-type ferrisiderophore, outer membrane receptor YP_914944.1 PFAM: periplasmic binding protein; KEGG: rsp:RSP_1439 ABC Fe+3 hydroxamate (ferrichrome) transporter, periplasmic siderophore binding protein YP_914945.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_914946.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_1437 ABC Fe+3 hydroxamate (ferrichrome) transporter, ATPase subunit YP_914947.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_3081 ABC multidrug efflux transporter, fused ATPase and inner membrane subunits YP_914948.1 KEGG: ret:RHE_CH03726 hypothetical protein YP_914949.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: ret:RHE_CH03725 hypothetical protein YP_914950.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bmb:BruAb1_1927 transcriptional regulator, LysR family YP_914951.1 PFAM: extracellular solute-binding protein, family 3; KEGG: bmb:BruAb1_1929 amino acid ABC transporter, periplasmic amino acid-binding protein YP_914952.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bme:BMEI0113 asparagine transport system permease protein YP_914953.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bmb:BruAb1_1931 amino acid ABC transporter, permease protein YP_914954.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bmb:BruAb1_1932 amino acid ABC transporter, ATP-binding protein YP_914955.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: bms:BR1957 arginase family protein YP_914956.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bms:BR1959 amino acid ABC transporter, ATP-binding protein YP_914957.1 PFAM: Asparaginase/glutaminase; KEGG: bmb:BruAb1_1936 L-asparaginase type II, hypothetical YP_914958.1 KEGG: mag:amb4044 site-specific recombinase YP_914960.1 KEGG: swo:Swol_1691 periplasmic binding protein YP_914961.1 KEGG: mta:Moth_1420 hypothetical protein YP_914962.1 KEGG: nwi:Nwi_2070 hypothetical protein YP_914963.1 PFAM: HPP family protein+B94; KEGG: son:SO1392 hypothetical protein YP_914964.1 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate YP_914965.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: csa:Csal_1087 arginase/agmatinase/formiminoglutamase YP_914966.1 PFAM: NUDIX hydrolase; KEGG: pfl:PFL_4894 hydrolase, NUDIX family YP_914967.1 PFAM: major facilitator superfamily MFS_1; KEGG: rsp:RSP_4025 major facilitator superfamily, fosmidomycin resistant protein YP_914968.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: ava:Ava_4058 hypothetical protein YP_914969.1 PFAM: periplasmic binding protein; KEGG: hin:HI1472 iron transport system substrate-binding protein YP_914970.1 PFAM: transport system permease protein; KEGG: eca:ECA3095 ABC transporter permease protein YP_914971.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rpa:RPA2310 iron ABC transporter ATP-binding protein YP_914972.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: nha:Nham_3366 TonB-dependent receptor YP_914973.1 PFAM: TOBE domain protein; KEGG: mlo:msr1466 molybdo-pterin binding protein YP_914974.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bpm:BURPS1710b_A0985 transcriptional regulator CatR YP_914975.1 KEGG: bam:Bamb_6587 muconate and chloromuconate cycloisomerases; TIGRFAM: muconate and chloromuconate cycloisomerases; PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein YP_914976.1 PFAM: Muconolactone delta-isomerase; KEGG: bam:Bamb_6586 muconolactone delta-isomerase YP_914977.1 TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein; KEGG: aci:ACIAD1442 catechol 1,2-dioxygenase YP_914978.1 PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein; KEGG: bur:Bcep18194_C7046 ring hydroxylating dioxygenase, alpha subunit YP_914979.1 PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit; KEGG: bur:Bcep18194_C7047 2-chlorobenzoate 1,2-dioxygenase YP_914980.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: bam:Bamb_6582 oxidoreductase FAD/NAD(P)-binding domain protein YP_914981.1 catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol YP_914982.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ppu:PP_3165 benzoate MFS transporter BenK YP_914983.1 TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; KEGG: xcb:XC_0382 b-ketoadipate enol-lactone hydrolase YP_914984.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: pau:PA14_47820 transcriptional regulator YP_914985.1 PFAM: proline racemase; KEGG: bmb:BruAb1_0363 hypothetical proline racemase YP_914986.1 PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: rsp:RSP_0854 predicted ornithine cyclodeaminase YP_914987.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein YP_914988.1 PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein; KEGG: rsp:RSP_4007 mandelate racemase/muconate lactonizing enzyme YP_914989.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit YP_914990.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMa0751 aromatic-ring hydroxylating dioxygenase, alpha-subunit YP_914991.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sme:SMa0750 probable LysR-family transcriptional activator YP_914992.1 PFAM: FAD dependent oxidoreductase; KEGG: mes:Meso_1861 FAD dependent oxidoreductase YP_914993.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: ret:RHE_PF00409 pyrroline-5-carboxylate reductase protein YP_914994.1 KEGG: ret:RHE_PF00412 probable amino acid ABC transporter, ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_914995.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02379 permease protein YP_914996.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc02378 periplasmic binding transmembrane protein YP_914997.1 PFAM: regulatory protein, TetR; KEGG: rsp:RSP_3680 transcriptional regulator, TetR family YP_914998.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ppu:PP_4753 N-methylproline demethylase YP_914999.1 PFAM: regulatory protein, MarR; KEGG: sil:SPO1261 transcriptional regulator, MarR family YP_915000.1 KEGG: sil:SPO1214 hippurate hydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_915001.1 KEGG: oih:OB0951 hypothetical protein YP_915002.1 KEGG: oih:OB0952 hypothetical protein YP_915003.1 PFAM: Resolvase, N-terminal domain; KEGG: bpm:BURPS1710b_2172 recombinase YP_915005.1 KEGG: mes:Meso_2004 D-alanine--D-alanine ligase; TIGRFAM: D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein YP_915006.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein, P47K; KEGG: rsp:RSP_0302 urease accessory protein G YP_915007.1 PFAM: Urease accessory protein UreF; KEGG: rsp:RSP_0303 urease accessory protein UreF YP_915008.1 PFAM: UreE urease accessory domain protein domain protein; UreE urease accessory domain protein; KEGG: rsp:RSP_0304 urease accessory protein UreE YP_915009.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_915010.1 KEGG: sme:SMc01939 urease beta subunit protein; TIGRFAM: urease, beta subunit; PFAM: Urease, beta subunit YP_915011.1 PFAM: HupE/UreJ protein; KEGG: pst:PSPTO_4912 urease accessory protein YP_915012.1 KEGG: rsp:RSP_0309 urease, gamma subunit; TIGRFAM: urease, gamma subunit; PFAM: Urease, gamma subunit region YP_915013.1 PFAM: Urease accessory protein UreD; KEGG: rsp:RSP_0310 urease accessory protein UreD YP_915015.1 PFAM: regulatory protein, ArsR; KEGG: atc:AGR_L_3580 hypothetical protein YP_915016.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: jan:Jann_2413 hypothetical protein YP_915017.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: atc:AGR_L_3582 hypothetical protein YP_915018.1 KEGG: ccr:CC1241 hypothetical protein YP_915022.1 PFAM: transposase, IS4 family protein; KEGG: nmu:Nmul_A2650 transposase, IS4 YP_915023.1 KEGG: mag:amb0408 transposase and inactivated derivative YP_915024.1 PFAM: phage integrase family protein; KEGG: rpc:RPC_3658 phage integrase YP_915028.1 KEGG: rpc:RPC_3654 hypothetical protein YP_915029.1 PFAM: helix-turn-helix domain protein; KEGG: rde:RD1_0810 DNA-binding protein YP_915030.1 KEGG: ilo:IL2080 hypothetical protein YP_915032.1 KEGG: ath:At4g01985 expressed protein YP_915033.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ccr:CC1477 hypothetical protein YP_915034.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_915035.1 KEGG: jan:Jann_3657 capsule polysaccharide export protein-like YP_915036.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: jan:Jann_3656 ABC transporter related YP_915037.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: sil:SPO0950 uracil-DNA glycosylase YP_915038.1 KEGG: sil:SPO0951 hypothetical protein YP_915039.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: rsp:RSP_2773 hypothetical protein YP_915041.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: rsp:RSP_2774 hypothetical protein YP_915042.1 TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; KEGG: rsp:RSP_2775 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase YP_915043.1 KEGG: jan:Jann_2147 phosphopantetheine-binding YP_915044.1 PFAM: beta-ketoacyl synthase; KEGG: rsp:RSP_2777 3-oxoacyl-(acyl-carrier-protein) synthase YP_915045.1 PFAM: major facilitator superfamily MFS_1; KEGG: rsp:RSP_2726 multidrug/metabolite efflux pump, major facilitator superfamily (MFS) YP_915046.1 KEGG: sil:SPO3031 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase YP_915047.1 KEGG: rsp:RSP_3425 hypothetical protein YP_915048.1 PFAM: glutathionylspermidine synthase; KEGG: rsp:RSP_3426 hypothetical protein YP_915049.1 PFAM: extracellular solute-binding protein, family 5; KEGG: sit:TM1040_0038 extracellular solute-binding protein, family 5 YP_915050.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sil:SPO1544 peptide/opine/nickel uptake family ABC transporter, permease protein YP_915051.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sit:TM1040_0036 binding-protein-dependent transport systems inner membrane component YP_915052.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sit:TM1040_0035 ABC transporter related YP_915053.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPO1547 peptide/opine/nickel uptake family ABC transporter, ATP-binding protein YP_915054.1 PFAM: protein of unknown function DUF125, transmembrane; KEGG: sit:TM1040_3365 protein of unknown function DUF125, transmembrane YP_915055.1 PFAM: aldehyde dehydrogenase; KEGG: bxe:Bxe_A3401 betaine-aldehyde dehydrogenase YP_915056.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_915057.1 PFAM: ABC-3 protein; KEGG: rsp:RSP_0908 ABC Mn+2/Fe+2 transporter, inner membrane subunit SitD YP_915058.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: sme:SMc02507 iron transport system membrane ABC transporter protein YP_915059.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMc02508 iron transport ATP-binding ABC transporter protein YP_915060.1 PFAM: periplasmic solute binding protein; KEGG: rsp:RSP_0904 ABC Mn+2/Fe+2 transporter, periplasmic substrate-binding protein SitA YP_915061.1 PFAM: ferric-uptake regulator; KEGG: sme:SMc02510 probable ferric uptake regulation protein YP_915062.1 PFAM: protein of unknown function UPF0029; KEGG: rde:RD1_4095 hypothetical protein YP_915063.1 KEGG: sil:SPO0809 hypothetical protein YP_915064.1 KEGG: sme:SMc03928 hypothetical protein YP_915065.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_915066.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_915067.1 binds and unfolds substrates as part of the ClpXP protease YP_915068.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis YP_915069.1 PFAM: Mammalian cell entry related domain protein; KEGG: rsp:RSP_0194 possible ABC transporter, substrate-binding protein YP_915070.1 KEGG: sil:SPO1008 hypothetical protein YP_915071.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_915072.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_915073.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: rsp:RSP_0190 biotin carboxyl carrier protein, AccB YP_915074.1 PFAM: lipid A biosynthesis acyltransferase; KEGG: rsp:RSP_2219 lipid A biosynthesis lauroyl acyltransferase YP_915075.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: jan:Jann_2643 protein of unknown function DUF6, transmembrane YP_915076.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_915078.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: sme:SMc02512 permease transmembrane protein YP_915079.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: rsp:RSP_2814 hypothetical protein with CBS domain YP_915080.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: rsp:RSP_2815 probable integrase/recombinase XerD YP_915081.1 KEGG: rsp:RSP_2816 hypothetical protein YP_915083.1 PFAM: shikimate kinase; KEGG: rsp:RSP_2817 shikimate kinase YP_915084.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_915085.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: rsp:RSP_3710 multicomponent K+:H+ antiporter subunit G YP_915086.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_915087.1 PFAM: cation antiporter; KEGG: rsp:RSP_3712 hypothetical protein YP_915088.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_915089.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_915090.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_915091.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: aeh:Mlg_0126 Orn/DAP/Arg decarboxylase 2 YP_915093.1 PFAM: AMP-dependent synthetase and ligase; KEGG: nmu:Nmul_A2670 AMP-dependent synthetase and ligase YP_915094.1 KEGG: mca:MCA1436 serine acetyltransferase CysE YP_915095.1 KEGG: pen:PSEEN2951 hypothetical protein YP_915096.1 KEGG: ccr:CC2454 lipase/acylhydrolase YP_915097.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: cps:CPS_4201 polysaccharide biosynthesis protein YP_915098.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: cps:CPS_4200 NAD-dependent epimerase/dehydratase family protein YP_915099.1 TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: sit:TM1040_1482 GDP-mannose 4,6-dehydratase YP_915100.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_915101.1 PFAM: protein of unknown function UPF0118; KEGG: jan:Jann_1056 protein of unknown function UPF0118 YP_915102.1 KEGG: rsp:RSP_0780 hypothetical protein with ATP/GTP-binding site YP_915103.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_915104.1 PFAM: Ppx/GppA phosphatase; KEGG: rsp:RSP_0782 Ppx/GppA phosphatase YP_915105.1 PFAM: peptidase M19, renal dipeptidase; KEGG: rsp:RSP_0802 dipeptidase YP_915106.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sil:SPO0462 antibiotic biosynthesis monooxygenase domain protein YP_915107.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: sil:SPO0461 ParA family protein YP_915108.1 KEGG: pol:Bpro_1343 hypothetical protein YP_915109.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_915110.1 PFAM: ETC complex I subunit conserved region; KEGG: sil:SPO0482 NADH-ubiquinone oxidoreductase family protein YP_915111.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: rpe:RPE_1965 periplasmic sensor signal transduction histidine kinase YP_915112.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mes:Meso_0894 two component transcriptional regulator, winged helix family YP_915115.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_915116.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_915117.1 KEGG: rme:Rmet_4886 hypothetical protein YP_915118.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_915119.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_915120.1 PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C; KEGG: sil:SPO0451 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase YP_915121.1 KEGG: rsp:RSP_0583 hypothetical protein YP_915122.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine YP_915123.1 KEGG: sil:SPO0459 hypothetical protein YP_915124.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: ret:RHE_CH03088 hypothetical protein YP_915125.1 KEGG: vvy:VV1207 ABC-type oligopeptide transport system, ATPase component; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_915126.1 KEGG: vpa:VP2088 oligopeptide ABC transporter, ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_915127.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_3052 binding-protein-dependent transport systems inner membrane component YP_915128.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_3051 binding-protein-dependent transport systems inner membrane component YP_915129.1 PFAM: extracellular solute-binding protein, family 5; KEGG: jan:Jann_3050 extracellular solute-binding protein, family 5 YP_915130.1 KEGG: nph:NP3544A thioredoxin reductase homolog YP_915131.1 KEGG: gbe:GbCGDNIH1_1136 cysteinyl-tRNA synthetase YP_915132.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: atc:AGR_L_3251 hypothetical protein YP_915133.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: bpm:BURPS1710b_A0955 DarR YP_915134.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: eci:UTI89_C1131 hypothetical protein YP_915135.1 KEGG: xcb:XC_2473 hypothetical protein YP_915136.1 KEGG: rpc:RPC_2661 riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding YP_915137.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_915138.1 KEGG: ppu:PP_3321 hypothetical protein YP_915139.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: rde:RD1_1856 cobalamin synthesis protein YP_915140.1 KEGG: jan:Jann_2253 hypothetical protein YP_915141.1 KEGG: rde:RD1_1858 hypothetical protein YP_915142.1 PFAM: extracellular solute-binding protein, family 5; KEGG: mfa:Mfla_2388 extracellular solute-binding protein, family 5 YP_915143.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vch:VCA1099 peptide transport system permease protein YP_915144.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mfa:Mfla_2390 binding-protein-dependent transport systems inner membrane component YP_915145.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vch:VCA1101 peptide transport system ATP-binding protein YP_915146.1 TIGRFAM: methylisocitrate lyase; KEGG: rpa:RPA2395 carboxyphosphonoenolpyruvate phosphonomutase YP_915147.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_915148.1 PFAM: MmgE/PrpD family protein; KEGG: rpc:RPC_3512 2-methylcitrate dehydratase YP_915149.1 PFAM: thioesterase superfamily protein; KEGG: rpc:RPC_3513 thioesterase superfamily YP_915150.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; KEGG: rru:Rru_A2316 transcriptional regulator, XRE family YP_915151.1 PFAM: LysR, substrate-binding; KEGG: atc:AGR_L_2015 transcription regulator MetR YP_915152.1 KEGG: bur:Bcep18194_C7370 hypothetical protein YP_915153.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_915155.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sme:SMb21433 methyl-transferase, S-adenosyl-L-methionine (SAM)-MTase protein YP_915156.1 TIGRFAM: pseudoazurin; PFAM: blue (type 1) copper domain protein; KEGG: rru:Rru_A1139 blue (type 1) copper subtype YP_915157.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20058 ABC transporter ATP-binding protein YP_915158.1 PFAM: transport system permease protein; KEGG: psp:PSPPH_3007 iron ABC transporter, permease protein YP_915159.1 PFAM: periplasmic binding protein; KEGG: rru:Rru_A1136 periplasmic binding protein YP_915160.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_915161.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_915162.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; KEGG: hne:HNE_1237 DNA-binding protein YP_915163.1 KEGG: rru:Rru_A1617 protein of unknown function DUF1289 YP_915164.1 PFAM: periplasmic binding protein; KEGG: rsp:RSP_2403 ABC cobalamin/Fe3+-siderophore transporter, periplasmic substrate-binding subunit YP_915165.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rru:Rru_A0488 TonB-dependent receptor YP_915169.1 KEGG: sme:SMb20398 hypothetical protein YP_915170.1 KEGG: rde:RD1_4059 Lon protease YP_915171.1 PFAM: metallophosphoesterase; KEGG: nha:Nham_1359 metallophosphoesterase YP_915173.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_915174.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rsp:RSP_2781 peroxiredoxin/glutaredoxin family protein YP_915175.1 KEGG: rsp:RSP_6073 hypothetical protein YP_915176.1 KEGG: rsp:RSP_6226 hypothetical protein YP_915177.1 PFAM: protein of unknown function DUF853, NPT hydrolase KEGG: sil:SPO1934 hypothetical protein YP_915178.1 PFAM: Invasion associated locus B family protein; KEGG: rsp:RSP_2778 hypothetical protein YP_915179.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: rsp:RSP_0355 possible serine protease YP_915181.1 Catalyzes the rate-limiting step in dNTP synthesis YP_915182.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: rsp:RSP_1898 5-formyltetrahydrofolate cyclo-ligase YP_915183.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: rsp:RSP_1897 Mg/Co/Ni transporter, MgtE YP_915184.1 PFAM: inositol monophosphatase; KEGG: rde:RD1_2006 inositol monophosphatase family protein YP_915185.1 PFAM: helix-turn-helix domain protein; KEGG: rsp:RSP_1892 Cro/CI transcriptional regulator YP_915186.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: jan:Jann_1231 alcohol dehydrogenase, zinc-binding YP_915187.1 PFAM: protein of unknown function UPF0005; KEGG: sil:SPO2963 membrane protein YP_915188.1 PFAM: BolA family protein; KEGG: rsp:RSP_2952 BolA-like protein YP_915189.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sil:SPO1868 glutaredoxin-related protein YP_915191.1 PFAM: protein of unknown function DUF883, ElaB; KEGG: rha:RHA1_ro00971 hypothetical protein YP_915192.1 PFAM: aminotransferase, class V; KEGG: rsp:RSP_1868 serine-pyruvate aminotransferase YP_915193.1 PFAM: glutamine amidotransferase class-I; KEGG: rsp:RSP_0376 glutamine amidotransferase class-I YP_915194.1 PFAM: glutamine synthetase, catalytic region; KEGG: rsp:RSP_0377 probable glutamine synthetase YP_915195.1 PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_0378 hypothetical protein YP_915196.1 KEGG: rsp:RSP_1671 hypothetical protein YP_915197.1 KEGG: rsp:RSP_1670 RelA/SpoT family protein; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_915198.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_915199.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: sil:SPO3205 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_915200.1 PFAM: protein of unknown function DUF88; KEGG: rsp:RSP_1667 hypothetical protein YP_915201.1 PFAM: OmpA/MotB domain protein; KEGG: rsp:RSP_2289 flagellar motor protein YP_915202.1 KEGG: rsp:RSP_2288 hypothetical protein YP_915203.1 PFAM: ChaC family protein; KEGG: rsp:RSP_2287 ChaC-like protein YP_915204.1 KEGG: rsp:RSP_2286 hypothetical protein YP_915205.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate YP_915206.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_915207.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: Redoxin domain protein; KEGG: rde:RD1_2551 thiol:disulfide interchange protein CycY YP_915208.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: rsp:RSP_1803 ABC heme exporter, inner membrane subunit CcmC YP_915209.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: rsp:RSP_1802 ABC heme exporter, inner membrane subunit CcmB YP_915210.1 ATP-binding protein; required for proper cytochrome c maturation YP_915211.1 PFAM: protein of unknown function DUF498; KEGG: rsp:RSP_1800 hypothetical protein YP_915212.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_915213.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_915214.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: rsp:RSP_1797 preprotein translocase subunit YajC YP_915215.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_915217.1 PFAM: dihydrouridine synthase, DuS; KEGG: sil:SPO2374 tRNA-dihydrouridine synthase A YP_915218.1 PFAM: phage integrase family protein; KEGG: hne:HNE_0292 site-specific recombinase, phage integrase family YP_915219.1 PFAM: protein of unknown function UPF0074; Helix-turn-helix, type 11 domain protein; KEGG: bte:BTH_II1478 transcriptional regulator family YP_915220.1 PFAM: HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bpm:BURPS1710b_A2517 pyridine nucleotide-disulphide oxidoreductase YP_915221.1 PFAM: Tellurite resistance protein TehB; thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: mmc:Mmcs_3339 methyltransferase type 12 YP_915222.1 PFAM: ABC transporter, transmembrane region; SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: gvi:gll0322 HlyB/MsbA family ABC transporter YP_915223.1 KEGG: mes:Meso_0337 major facilitator superfamily MFS_1 YP_915224.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pau:PA14_55050 possible TonB-dependent receptor YP_915225.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: pae:PA2281 probable transcriptional regulator YP_915226.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ret:RHE_CH02787 probable amino acid efflux protein, LysE family YP_915228.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: rsp:RSP_1925 transcriptional regulator, GntR family YP_915229.1 PFAM: BioY protein; KEGG: rsp:RSP_1924 BioY family protein YP_915230.1 KEGG: rsp:RSP_1923 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_915231.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: rsp:RSP_1922 transcriptional regulator, GntR family, with aminotransferase domain YP_915232.1 PFAM: glutamine amidotransferase class-I; KEGG: rru:Rru_A3512 glutamine amidotransferase class-I YP_915233.1 PFAM: 3-alpha; MOSC domain containing protein; KEGG: rsp:RSP_1921 MOSC domain protein YP_915234.1 TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: rsp:RSP_1920 pyridoxal/pyridoxine/pyridoxamine kinase YP_915235.1 KEGG: bte:BTH_I2719 pathogenesis-related protein YP_915236.1 KEGG: bte:BTH_I2720 hypothetical protein YP_915238.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: hne:HNE_1462 thioesterase family protein YP_915240.1 KEGG: hne:HNE_1461 conserved hypothetical protein TIGR02246 YP_915241.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: xcb:XC_1877 hypothetical protein YP_915243.1 PFAM: major facilitator superfamily MFS_1; KEGG: reu:Reut_A2630 major facilitator superfamily MFS_1 YP_915244.1 PFAM: PEBP family protein; KEGG: rpa:RPA0709 hypothetical protein YP_915245.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: zmo:ZMO1945 predicted epimerase YP_915246.1 KEGG: rsp:RSP_1919 hypothetical protein YP_915247.1 KEGG: rsp:RSP_1918 predicted alpha/beta hydrolase YP_915248.1 PFAM: protein of unknown function DUF1330; KEGG: mmc:Mmcs_0720 protein of unknown function DUF1330 YP_915249.1 KEGG: jan:Jann_1547 DNA polymerase, beta-like YP_915250.1 KEGG: rme:Rmet_1656 glutathione S-transferase-like protein YP_915251.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: rpe:RPE_0479 major facilitator superfamily MFS_1 YP_915252.1 PFAM: helix-turn-helix, HxlR type; KEGG: sit:TM1040_2008 transcriptional regulator, HxlR family YP_915253.1 KEGG: rsp:RSP_1918 predicted alpha/beta hydrolase YP_915254.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: rsp:RSP_1917 hypothetical protein YP_915255.1 PFAM: DSBA oxidoreductase; KEGG: rsp:RSP_1916 possible 2-hydroxychromene-2-carboxylate isomerase YP_915256.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_6026 acetyltransferase YP_915257.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rru:Rru_A3458 GCN5-related N-acetyltransferase YP_915258.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ret:RHE_CH02190 probable acetyltransferase protein YP_915259.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rsp:RSP_1915 transcriptional regulator, LysR family YP_915260.1 PFAM: aminotransferase, class IV; KEGG: rru:Rru_A2223 branched-chain amino acid aminotransferase I YP_915261.1 KEGG: atc:AGR_C_4899 hypothetical transmembrane protein YP_915262.1 SMART: helix-turn-helix- domain containing protein, AraC type; KEGG: cvi:CV1825 probable transcriptional regulator, AraC family YP_915263.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: gbe:GbCGDNIH1_1691 transporter, LysE family YP_915264.1 PFAM: protein of unknown function DUF1234; KEGG: bur:Bcep18194_B2508 protein of unknown function DUF1234 YP_915265.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: bur:Bcep18194_B2509 transcriptional regulator, AsnC family YP_915266.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: jan:Jann_1597 lysine exporter protein (LysE/YggA) YP_915267.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mes:Meso_3862 transcriptional regulator, LysR family YP_915268.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; Methyltransferase type 11; Methyltransferase type 12; SMART: Tetratricopeptide domain protein; KEGG: mag:amb4019 predicted methyltransferase YP_915269.1 PFAM: MaoC domain protein dehydratase; KEGG: mag:amb1218 acyl dehydratase YP_915270.1 KEGG: gbe:GbCGDNIH1_1065 hypothetical protein YP_915271.1 PFAM: conjugation TrbI family protein; KEGG: mes:Meso_0500 conjugation TrbI-like protein YP_915272.1 PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: mes:Meso_0501 conjugal transfer protein TrbG/VirB9/CagX YP_915273.1 PFAM: Conjugal transfer protein; KEGG: mes:Meso_0502 conjugal transfer protein YP_915274.1 type IV secretion VirB6 family YP_915275.1 KEGG: mes:Meso_2319 hypothetical protein YP_915276.1 KEGG: mes:Meso_3855 conjugal transfer protein TrbJ YP_915277.1 type IV secretion system VirB4 family YP_915278.1 KEGG: mlo:mll9611 conjugal transfer protein trbB YP_915279.1 PFAM: Conjugal transfer protein TrbC; KEGG: mes:Meso_2323 conjugal transfer protein TrbC YP_915280.1 PFAM: type II secretion system protein E; KEGG: mes:Meso_2324 type II secretion system protein E YP_915281.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: rru:Rru_A1456 transcriptional regulator, AraC family YP_915282.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rru:Rru_A1458 TonB-dependent receptor YP_915283.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: rru:Rru_A1457 O-methyltransferase, family 2 YP_915284.1 KEGG: atc:AGR_L_928 sulfonate/nitrate transport system substrate-binding protein YP_915285.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rpc:RPC_1932 binding-protein-dependent transport systems inner membrane component YP_915286.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: swo:Swol_0339 sulfonate transport system ATP-binding protein YP_915287.1 PFAM: regulatory protein, TetR; KEGG: nfa:nfa16940 transcriptional regulator YP_915288.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cdi:DIP2158 ABC transport protein YP_915289.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: gvi:gll0322 HlyB/MsbA family ABC transporter YP_915290.1 PFAM: monooxygenase, FAD-binding; KEGG: sme:SMc02891 oxidoreductase transmembrane protein YP_915291.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sme:SMc02890 outer membrane receptor protein YP_915292.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc02889 transport protein YP_915293.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: sme:SMc02888 transcription regulator protein YP_915294.1 PFAM: major facilitator superfamily MFS_1; KEGG: rru:Rru_A2336 major facilitator superfamily MFS_1 YP_915295.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rru:Rru_A2337 TonB-dependent receptor YP_915296.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: yps:YPTB1597 transcriptional regulator YbtA YP_915297.1 PFAM: protein of unknown function DUF454; KEGG: nha:Nham_3232 protein of unknown function DUF454 YP_915298.1 KEGG: mxa:MXAN_7409 hypothetical protein YP_915299.1 PFAM: monooxygenase, FAD-binding; KEGG: nwi:Nwi_2327 hypothetical protein YP_915301.1 KEGG: mlo:mlr9748 hypothetical protein YP_915302.1 type IV secretion VirD4 coupling protein family YP_915303.1 KEGG: bja:bll0044 hypothetical protein YP_915304.1 PFAM: Lytic transglycosylase, catalytic; KEGG: mes:Meso_2331 lytic transglycosylase, catalytic YP_915305.1 PFAM: protein of unknown function DUF736; KEGG: mes:Meso_2332 protein of unknown function DUF736 YP_915306.1 KEGG: mes:Meso_2333 conjugal transfer protein precursor YP_915307.1 KEGG: rpc:RPC_3907 hypothetical protein YP_915308.1 KEGG: mlo:mlr9740 replication protein A YP_915309.1 KEGG: mlo:msr9739 hypothetical protein YP_915310.1 KEGG: mes:Meso_0525 hypothetical protein YP_915311.1 KEGG: mes:Meso_3837 hypothetical protein YP_915312.1 KEGG: mes:Meso_0527 hypothetical protein YP_915313.1 KEGG: mes:Meso_0528 transcriptional regulator, XRE family YP_915314.1 PFAM: protein of unknown function DUF736; KEGG: mes:Meso_0529 protein of unknown function DUF736 YP_915316.1 KEGG: mes:Meso_2343 hypothetical protein YP_915317.1 KEGG: bcz:BCZK2630 2'-5' RNA ligase YP_915319.1 KEGG: gox:GOX1507 restriction endonuclease YP_915320.1 KEGG: gox:GOX1506 chromosome segregation SMC protein YP_915321.1 KEGG: gox:GOX1505 type II DNA modification enzyme YP_915322.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like; KEGG: gox:GOX1504 ATP-dependent helicase HepA YP_915323.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: gox:GOX1503 probable ATP-dependent helicase Lhr YP_915324.1 PFAM: protein of unknown function DUF262; KEGG: rha:RHA1_ro01680 hypothetical protein YP_915325.1 KEGG: nar:Saro_2176 hypothetical protein YP_915326.1 KEGG: rsp:RSP_3007 hypothetical protein YP_915327.1 KEGG: mes:Meso_0533 hypothetical protein YP_915328.1 KEGG: nwi:Nwi_2129 hypothetical protein YP_915329.1 KEGG: mes:Meso_3828 probably methylase/helicase YP_915330.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: rpc:RPC_1039 filamentation induced by cAMP protein Fic YP_915331.1 KEGG: mes:Meso_0536 hypothetical protein YP_915332.1 KEGG: mes:Meso_3827 hypothetical protein YP_915333.1 KEGG: net:Neut_0078 hypothetical protein YP_915334.1 KEGG: mlo:msr9708 hypothetical protein YP_915336.1 KEGG: sil:SPO2244 hypothetical protein YP_915337.1 TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: mes:Meso_0538 ParB-like partition proteins YP_915338.1 PFAM: DNA repair protein RadC; KEGG: rsp:RSP_1171 DNA repair protein YP_915339.1 KEGG: nwi:Nwi_2122 hypothetical protein YP_915340.1 PFAM: domain of unknown function DUF1738; KEGG: nwi:Nwi_2121 antirestriction protein; ArdC YP_915341.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: rsp:RSP_4056 histone-like nucleoid-structuring protein H-NS YP_915342.1 similar to plasmid pRiA4b; PFAM: plasmid pRiA4b ORF-3 family protein; KEGG: sme:SMa0896 hypothetical protein YP_915343.1 PFAM: helix-turn-helix domain protein; KEGG: rpb:RPB_0688 transcriptional regulator, XRE family YP_915344.1 PFAM: HipA domain protein; KEGG: rpb:RPB_0687 HipA-like protein YP_915345.1 KEGG: rsp:RSP_6129 hypothetical protein YP_915346.1 PFAM: protein of unknown function DUF1052; KEGG: sil:SPO1766 hypothetical protein YP_915347.1 PFAM: protein of unknown function DUF481; KEGG: rsp:RSP_0753 salt-stress induced outer membrane protein YP_915348.1 KEGG: rsp:RSP_0754 hypothetical protein YP_915349.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44; KEGG: jan:Jann_3412 NusB antitermination factor YP_915350.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_915351.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: jan:Jann_3414 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_915352.1 KEGG: sil:SPO1760 hypothetical protein YP_915353.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_915354.1 PFAM: Capsule polysaccharide biosynthesis; KEGG: sil:SPO1757 capsular polysaccharide export protein KpsS YP_915355.1 PFAM: polysaccharide export protein; KEGG: sit:TM1040_2133 polysaccharide export protein YP_915356.1 PFAM: Capsule polysaccharide biosynthesis; KEGG: sil:SPO1755 capsular polysaccharide export protein KpsC YP_915357.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: sit:TM1040_2135 riboflavin biosynthesis protein RibD YP_915358.1 PFAM: ATP-cone domain protein; KEGG: rsp:RSP_0394 hypothetical protein YP_915359.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rsp:RSP_0097 TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, SmoM YP_915360.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rsp:RSP_6094 TRAP-T family sorbitol/mannitol transporter, DctM (12TMs) subunit YP_915361.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: rsp:RSP_0099 TRAP-T family sorbitol/mannitol transporter, DctQ (4TMs) subunit YP_915362.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; KEGG: bja:bll3255 cobalamin (5'-phosphate) synthase YP_915363.1 PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: sil:SPO1423 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_915364.1 PFAM: cobalbumin biosynthesis enzyme; KEGG: bja:bll3256 cobinamide kinase / conamide phosphate guanylyltransferase YP_915365.1 PFAM: extracellular solute-binding protein, family 5; KEGG: jan:Jann_3050 extracellular solute-binding protein, family 5 YP_915366.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_3051 binding-protein-dependent transport systems inner membrane component YP_915367.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_3052 binding-protein-dependent transport systems inner membrane component YP_915368.1 KEGG: vpa:VP2088 oligopeptide ABC transporter, ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_915369.1 KEGG: vvy:VV1207 ABC-type oligopeptide transport system, ATPase component; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_915370.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: ret:RHE_CH03088 hypothetical protein YP_915371.1 KEGG: sil:SPO0459 hypothetical protein YP_915372.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine YP_915373.1 KEGG: rsp:RSP_0583 hypothetical protein YP_915374.1 PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C; KEGG: sil:SPO0451 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase YP_915375.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_915376.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_915377.1 KEGG: rme:Rmet_4886 hypothetical protein YP_915378.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_915379.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_915381.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mes:Meso_0894 two component transcriptional regulator, winged helix family YP_915382.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: mmr:Mmar10_0937 periplasmic sensor signal transduction histidine kinase YP_915383.1 PFAM: ETC complex I subunit conserved region; KEGG: sil:SPO0482 NADH-ubiquinone oxidoreductase family protein YP_915384.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_915385.1 KEGG: pol:Bpro_1343 hypothetical protein YP_915386.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: sil:SPO0461 ParA family protein YP_915387.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sil:SPO0462 antibiotic biosynthesis monooxygenase domain protein YP_915388.1 PFAM: peptidase M19, renal dipeptidase; KEGG: rsp:RSP_0802 dipeptidase YP_915389.1 PFAM: Ppx/GppA phosphatase; KEGG: rsp:RSP_0782 Ppx/GppA phosphatase YP_915390.1 PFAM: Polyphosphate kinase; KEGG: rde:RD1_2042 polyphosphate kinase YP_915391.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mlo:mll8315 ABC transporter, ATP-binding protein YP_915392.1 PFAM: ABC-3 protein; KEGG: mlo:mll8314 ABC transporter, permease protein YP_915393.1 PFAM: periplasmic solute binding protein; KEGG: atc:AGR_L_3262 adhesin, probable YP_915394.1 KEGG: mes:Meso_4007 hypothetical protein YP_915395.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: sme:SMc00594 beta-etherase (beta-aryl ether cleaving enzyme) protein YP_915396.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cvi:CV3061 probable transcriptional regulator, LysR family YP_915397.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc02892 transport protein YP_915398.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: ilo:IL0069 outer membrane protein YP_915399.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sme:SMb20019 dihydrolipoamide succinyltransferase protein YP_915400.1 PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sme:SMb20020 pyruvate dehydrogenase E1 component,alpha and beta subunits protein YP_915401.1 PFAM: flavoprotein; KEGG: bcl:ABC3557 lantibiotic biosynthesis protein, flavoprotein YP_915402.1 PFAM: Methyltransferase type 12; KEGG: cps:CPS_2928 hypothetical protein YP_915403.1 PFAM: MaoC domain protein dehydratase; KEGG: nha:Nham_0934 phenylacetic acid degradation protein PaaN YP_915404.1 PFAM: extracellular solute-binding protein, family 5; KEGG: wsu:WS1160 oligopeptide binding protein YP_915405.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dsy:DSY3210 hypothetical protein YP_915406.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mac:MA0843 dipeptide ABC transporter, permease YP_915407.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sma:SAV3045 ABC transporter ATP-binding protein YP_915408.1 PFAM: ChaC family protein; KEGG: rsp:RSP_2287 ChaC-like protein YP_915409.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: bca:BCE_5473 acyl-CoA dehydrogenase YP_915410.1 PFAM: thioesterase superfamily protein; KEGG: sth:STH878 hypothetical protein YP_915411.1 KEGG: bld:BLi04239 YwfB YP_915412.1 PFAM: transposase IS3/IS911 family protein; KEGG: nwi:Nwi_2119 transposase IS3/IS911 YP_915413.1 KEGG: sil:SPO3456 flagellar protein YP_915414.1 PFAM: flagellar FlaF family protein; KEGG: rde:RD1_0159 flagellar protein YP_915415.1 PFAM: flagellin domain protein; KEGG: sit:TM1040_3134 flagellin-like YP_915417.1 KEGG: rde:RD1_0163 flagellar hook-length control protein YP_915418.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Rhodobacter sphaeroides has 2 copies of many flagellar genes; the Rhodobacter protein in this cluster is associated with a set of flagellar genes acquired by lateral gene transfer; these genes are not normally expressed YP_915419.1 PFAM: transposase IS3/IS911 family protein; KEGG: ret:RHE_CH03058 probable insertion sequence transposase protein YP_915421.1 KEGG: stm:STM1586 periplasmic protein YP_915422.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: bbr:BB4761 exogenous ferric siderophore receptor YP_915423.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: pfo:Pfl_0929 sigma-24 (FecI) YP_915424.1 PFAM: FecR protein; KEGG: nwi:Nwi_2882 FecR protein YP_915425.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: csa:Csal_2678 TonB-dependent siderophore receptor YP_915427.1 ATP-dependent carboxylate-amine ligase YP_915428.1 PFAM: superoxide dismutase, copper/zinc binding; KEGG: ret:RHE_CH01400 superoxide dismutase protein YP_915429.1 PFAM: HWE histidine kinase; KEGG: mes:Meso_0180 signal transduction histidine kinase YP_915430.1 PFAM: isochorismatase hydrolase; KEGG: mlo:mlr6855 hypothetical protein YP_915431.1 KEGG: rsp:RSP_2671 hypothetical protein YP_915432.1 KEGG: bbr:BB2396 hypothetical protein YP_915433.1 KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase YP_915434.1 PFAM: conserved hypothetical protein 698; KEGG: rsp:RSP_4010 conserved hypothetical protein 698 YP_915435.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_915436.1 PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_4012 FAD dependent oxidoreductase YP_915437.1 PFAM: protein of unknown function DUF1486; KEGG: rsp:RSP_4013 hypothetical protein YP_915438.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rsp:RSP_4014 TRAP-T family transporter, large inner membrane subunit DctM YP_915439.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: rsp:RSP_4015 TRAP-T family transporter, periplasmic ligand binding protein, DctQ YP_915440.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rsp:RSP_4016 TRAP-T family transporter, DctP subunit YP_915441.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: rsp:RSP_4017 transcriptional regulator, GntR family YP_915442.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_915443.1 PFAM: beta-ketoacyl synthase; KEGG: rsp:RSP_3177 3-oxoacyl-(acyl-carrier-protein) synthase YP_915444.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_3176 enoyl-(acyl-carrier protein) reductase (NADH) YP_915445.1 KEGG: rsp:RSP_2253 predicted hydrolase or acyltransferase YP_915446.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: rsp:RSP_1125 membrane bound lytic murein transglycosylase B YP_915447.1 PFAM: tRNA synthetase, class II (D, K and N); KEGG: rsp:RSP_0478 lysyl-tRNA synthetase YP_915448.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_915449.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_915450.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_915451.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_915452.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_3512 periplasmic sensor signal transduction histidine kinase YP_915453.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rsp:RSP_3511 two component transcriptional regulator, winged helix family family YP_915454.1 PFAM: Propeptide, PepSY amd peptidase M4; KEGG: rsp:RSP_3510 hypothetical protein YP_915455.1 PFAM: Hemolysin-type calcium-binding region; KEGG: rsp:RSP_3509 hemolysin-type calcium-binding region, RTX YP_915456.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: gbe:GbCGDNIH1_0274 rieske (2Fe-2S) domain protein YP_915457.1 KEGG: sme:SMc03211 4-hydroxyphenylpyruvate dioxygenase protein; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_915458.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: rpa:RPA0006 transcriptional regulator, AsnC family YP_915459.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: rsp:RSP_3227 lysine 2,3-aminomutase YP_915460.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; KEGG: atc:AGR_L_1474 probable ATP-binding component of ABC dipeptide transporter YP_915461.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; KEGG: atc:AGR_L_1475 probable ATP-binding component of ABC transporter YP_915462.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_1477 probable permease of ABC transporter YP_915463.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_1478 dipeptide transport system permease protein DppB YP_915464.1 PFAM: extracellular solute-binding protein, family 5; KEGG: atc:AGR_L_1481 dipeptide transport protein YP_915465.1 PFAM: Myo-inositol catabolism IolB domain protein; KEGG: bmb:BruAb2_0514 IolB protein YP_915466.1 KEGG: ret:RHE_CH03169 hypothetical protein YP_915467.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: atc:AGR_L_177GM iolE protein YP_915468.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rsp:RSP_3284 acetolactate synthase YP_915469.1 PFAM: PfkB domain protein; KEGG: bmb:BruAb2_0517 IolC myo-catabolism protein YP_915470.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: atc:AGR_L_627 IolI protein YP_915471.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: atc:AGR_L_628 myo-inositol 2-dehydrogenase YP_915472.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: atc:AGR_pAT_639 myo-inositol catabolism YP_915473.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: psb:Psyr_2455 oxidoreductase, N-terminal:oxidoreductase, C-terminal YP_915474.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: atc:AGR_L_632 rhizopine-binding protein precursor YP_915475.1 PFAM: inner-membrane translocator; KEGG: sme:SMb20714 sugar uptake ABC transporter permease protein YP_915476.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_L_2903 D-galactose transport system ATP-binding protein YP_915477.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: atc:AGR_L_634 rhizopine-binding protein precursor YP_915478.1 PFAM: regulatory protein, LacI; KEGG: atc:AGR_L_636 hypothetical protein YP_915479.1 KEGG: bja:blr7843 hypothetical protein YP_915480.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: sil:SPO1002 transcriptional regulator, AraC family YP_915481.1 KEGG: nmu:Nmul_A2076 hypothetical protein YP_915482.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_915483.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: neu:NE0928 hypothetical protein YP_915484.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: atc:AGR_C_2527 hypothetical protein YP_915485.1 PFAM: creatinase; peptidase M24; KEGG: rxy:Rxyl_0461 creatinase YP_915486.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ppu:PP_3666 metabolite MFS transporter, MHS family YP_915487.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rsp:RSP_1286 RuBisCO operon transcriptional regulator, CbbR YP_915488.1 PFAM: Inositol phosphatase/fructose-1,6-bisphosphatase; KEGG: rsp:RSP_1285 fructose-1,6-bisphosphatase I YP_915489.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: rsp:RSP_1284 phosphoribulokinase YP_915490.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_915491.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_915492.1 type III RuBisCO; involved in carbon fixation YP_915493.1 PFAM: ribulose bisphosphate carboxylase, small chain; KEGG: rpa:RPA1560 ribulose-bisphosphate carboxylase small chain YP_915494.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_1280 CbbX protein YP_915495.1 KEGG: pfl:PFL_4132 PimS2 protein YP_915496.1 KEGG: pfo:Pfl_2975 quinohemoprotein amine dehydrogenase, 60 kDa subunit YP_915497.1 PFAM: Radical SAM domain protein; KEGG: pfo:Pfl_2974 radical SAM YP_915498.1 KEGG: pfo:Pfl_2973 hypothetical protein YP_915499.1 KEGG: pfo:Pfl_2972 quinohemoprotein amine dehydrogenase, subunit beta YP_915500.1 KEGG: pfo:Pfl_2971 hypothetical protein YP_915501.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: pfl:PFL_4134 ABC transporter, ATP-binding protein, MsbA family YP_915502.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: nar:Saro_2605 transcriptional regulator, AraC family YP_915503.1 PFAM: aldehyde dehydrogenase; KEGG: nar:Saro_1692 aldehyde dehydrogenase YP_915504.1 KEGG: nwi:Nwi_2052 hypothetical protein YP_915505.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: rsp:RSP_3292 glucose-methanol-choline oxidoreductase YP_915506.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_3293 ABC branched-chain amino acid transporter, inner membrane subunit YP_915507.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_3294 ABC branched-chain amino acid transporter, inner membrane subunit YP_915508.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_3295 ABC branched-chain amino acid transporter, ATPase subunit YP_915509.1 PFAM: ABC transporter related; KEGG: rsp:RSP_3296 ABC branched-chain amino acid transporter, ATPase subunit YP_915510.1 KEGG: rsp:RSP_3297 ABC branched-chain amino acid transporter, periplasmic binding protein YP_915511.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rsp:RSP_3298 transcriptional regulator, LysR family YP_915512.1 catalyzes the formation of malonyl-CoA from malonate and CoA YP_915513.1 PFAM: Malonyl-CoA decarboxylase; KEGG: rpb:RPB_0704 malonyl-CoA decarboxylase YP_915514.1 PFAM: Citrate transporter; Dicarboxylate carrier MatC domain protein; KEGG: rha:RHA1_ro02937 possible dicarboxylate carrier protein YP_915515.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: dar:Daro_4024 regulatory protein GntR, HTH:GntR, C-terminal YP_915516.1 KEGG: bxe:Bxe_C1278 hypothetical protein YP_915517.1 KEGG: bbr:BB1601 hypothetical protein YP_915519.1 KEGG: sme:SMc02592 hypothetical protein YP_915520.1 KEGG: sme:SMc02593 hypothetical protein YP_915521.1 PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: mlo:mll9114 hypothetical protein YP_915522.1 TIGRFAM: alanine dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; alanine dehydrogenase/PNT domain protein; KEGG: sit:TM1040_3628 alanine dehydrogenase YP_915524.1 TIGRFAM: sulfate transporter; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter; KEGG: sit:TM1040_3648 sulfate permease YP_915525.1 KEGG: sil:SPO3222 glutathione S-transferase YP_915526.1 PFAM: iron permease FTR1; KEGG: rru:Rru_A2597 iron permease FTR1 YP_915527.1 PFAM: protein of unknown function DUF451; KEGG: rru:Rru_A2598 hypothetical protein YP_915528.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: rru:Rru_A2599 Tat-translocated enzyme YP_915529.1 PFAM: protein of unknown function DUF451; KEGG: rru:Rru_A2600 protein of unknown function DUF451 YP_915530.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: ret:RHE_CH00925 probable transcriptional regulator protein, LysR family YP_915531.1 PFAM: creatinase; peptidase M24; KEGG: rxy:Rxyl_0461 creatinase YP_915532.1 KEGG: rsp:RSP_1883 ABC polyamine/opine transporter, periplasmic substrate-binding protein YP_915533.1 KEGG: rde:RD1_2835 hypothetical protein YP_915534.1 KEGG: sit:TM1040_1503 conserved hypothetical protein YP_915535.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_915536.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_0819 DEAD/DEAH box helicase YP_915537.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_915538.1 PFAM: YceI family protein; cytochrome B561; KEGG: sit:TM1040_1049 cytochrome b561 YP_915539.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_915540.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2895 ABC transporter, fused ATPase subunits YP_915541.1 PFAM: MltA-interacting MipA family protein; KEGG: rpc:RPC_0793 MltA-interacting MipA YP_915542.1 PFAM: protein of unknown function DUF59; KEGG: rde:RD1_2957 hypothetical protein YP_915543.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: rde:RD1_2959 maltose O-acetyltransferase YP_915544.1 PFAM: Phosphoglycerate mutase; KEGG: rde:RD1_2834 phosphoglycerate mutase YP_915545.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_915546.1 KEGG: rsp:RSP_0683 hypothetical protein YP_915547.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_0684 possible oxidoreductase; short-chain dehydrogenase/reductase SDR YP_915548.1 PFAM: methyltransferase small; KEGG: rsp:RSP_0685 possible ribosomal RNA small subunit methyltransferase C RsmC YP_915549.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: sit:TM1040_2534 ATP-dependent Clp protease adaptor protein ClpS YP_915550.1 PFAM: beta-lactamase; peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; KEGG: rsp:RSP_0688 probable penicillin-binding protein YP_915551.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: rsp:RSP_1867 transcriptional regulator, AsnC family YP_915552.1 PFAM: regulatory protein, AsnC/Lrp family; Helix-turn-helix, type 11 domain protein; KEGG: rsp:RSP_1866 transcriptional regulator, AsnC family YP_915553.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_915554.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: rsp:RSP_1649 possible transporter, DMT superfamily YP_915555.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_915556.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rde:RD1_4071 sugar ABC transporter, ATP-binding protein YP_915557.1 PFAM: inner-membrane translocator; KEGG: sit:TM1040_0495 inner-membrane translocator YP_915558.1 PFAM: inner-membrane translocator; KEGG: sil:SPO0649 sugar ABC transporter, permease protein YP_915559.1 PFAM: basic membrane lipoprotein; KEGG: rsp:RSP_3560 possible ABC transporter, periplasmic binding protein YP_915560.1 PFAM: Ferritin, Dps family protein; KEGG: gbe:GbCGDNIH1_0685 ferroxidase YP_915561.1 carries the fatty acid chain in fatty acid biosynthesis YP_915562.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sit:TM1040_1051 3-oxoacyl-(acyl-carrier-protein) reductase YP_915563.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: sit:TM1040_1050 malonyl CoA-acyl carrier protein transacylase YP_915564.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sil:SPO2173 sensor histidine kinase YP_915565.1 PFAM: beta-lactamase domain protein; KEGG: sil:SPO2174 metallo-beta-lactamase family protein YP_915566.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: mes:Meso_0336 siderophore-interacting protein YP_915567.1 KEGG: rpc:RPC_3611 periplasmic binding protein YP_915568.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: neu:NE1097 TonB-dependent receptor protein YP_915569.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: bam:Bamb_1692 transcriptional regulator, AraC family YP_915570.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: pau:PA14_14360 sodium/sulphate transporter YP_915571.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: rsp:RSP_2851 multidrug (bicyclomycin) efflux pump, major facilitator superfamily (MFS) YP_915572.1 PFAM: Uncharacterized conserved protein UCP032025; KEGG: rsp:RSP_3548 hypothetical protein YP_915573.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rsp:RSP_3321 cation/multidrug efflux pump, membrane-fusion protein YP_915574.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: rsp:RSP_3318 cation/multidrug efflux pump, RND family YP_915575.1 KEGG: rsp:RSP_3318 cation/multidrug efflux pump, RND family YP_915576.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: rpe:RPE_2819 signal transduction histidine kinase, glucose-6-phosphate specific YP_915577.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: rpe:RPE_3142 two component transcriptional regulator, LuxR family YP_915578.1 PFAM: helix-turn-helix domain protein; KEGG: rsp:RSP_0172 predicted transcriptional regulators YP_915579.1 PFAM: response regulator receiver; KEGG: rde:RD1_2841 response regulator receiver domain protein YP_915580.1 KEGG: rsp:RSP_0170 hypothetical protein YP_915581.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_0169 Na+/solute symporter YP_915582.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: rsp:RSP_6099 possible flagellar switch protein FliM YP_915583.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_915584.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: rsp:RSP_0625 Maf-like protein YP_915585.1 KEGG: rsp:RSP_0624 ribonuclease YP_915586.1 PFAM: protein of unknown function DUF329; KEGG: rpe:RPE_4479 protein of unknown function DUF329 YP_915588.1 PFAM: Allergen V5/Tpx-1 family protein; Hemolysin-type calcium-binding region; KEGG: eba:ebA7184 hypothetical protein YP_915589.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_2081 acetyltransferase, GNAT family YP_915590.1 KEGG: rsp:RSP_3696 ABC sulfate/thiosulfate transporter, ATPase subunit CysA; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_915591.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; KEGG: rsp:RSP_3697 ABC sulfate/thiosulfate transporter, periplasmic binding protein CysP YP_915592.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_3698 ABC sulfate/thiosulfate transporter, inner membrane subunit CysT YP_915593.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_3699 ABC sulfate/thiosulfate transporter, inner membrane subunit CysW YP_915594.1 PFAM: heat shock protein DnaJ domain protein; KEGG: rsp:RSP_0785 heat shock protein DnaJ YP_915595.1 KEGG: rsp:RSP_6229 hypothetical protein YP_915596.1 PFAM: glycosyl transferase, group 1; KEGG: rsp:RSP_0700 probable glycosyltransferase YP_915597.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_0701 ABC peptide transporter, fused ATPase domains YP_915598.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0702 ABC peptide transporter, inner membrane subunit YP_915599.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_1264 peptide ABC transporter, permease protein YP_915600.1 PFAM: extracellular solute-binding protein, family 5; KEGG: rsp:RSP_0704 ABC peptide transporter, substrate binding protein YP_915601.1 PFAM: cytochrome c, class I; KEGG: sil:SPO3538 cytochrome c552 YP_915602.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_915603.1 KEGG: sit:TM1040_0171 conserved hypothetical protein YP_915604.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sit:TM1040_1036 twin-arginine translocation pathway signal YP_915605.1 PFAM: PfkB domain protein; KEGG: sil:SPO2060 kinase, PfkB family YP_915606.1 PFAM: Indigoidine synthase A family protein; KEGG: rsp:RSP_2858 IndA involved in pigment biosynthesis YP_915607.1 PFAM: Patatin; KEGG: jan:Jann_2313 patatin YP_915608.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_915609.1 KEGG: rsp:RSP_2978 penicillin-binding protein 1A (PBP-1a); TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_915610.1 PFAM: cell wall hydrolase/autolysin; KEGG: sil:SPO2588 N-acetylmuramoyl-L-alanine amidase, family 3 YP_915611.1 PFAM: aminotransferase, class I and II; KEGG: rsp:RSP_2980 aspartate aminotransferase A YP_915612.1 PFAM: DSBA oxidoreductase; KEGG: rde:RD1_2824 outer membrane protein YP_915613.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_915614.1 KEGG: rsp:RSP_2983 hypothetical protein YP_915615.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_915616.1 PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: rsp:RSP_2986 hypothetical protein YP_915617.1 KEGG: rpa:RPA2196 hypothetical protein YP_915618.1 PFAM: transcription factor CarD; KEGG: rsp:RSP_2425 CarD-like transcriptional regulator YP_915619.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sit:TM1040_0575 4Fe-4S ferredoxin, iron-sulfur binding YP_915620.1 PFAM: RNA-binding S4 domain protein; KEGG: sil:SPO1418 S4 domain protein YP_915621.1 PFAM: helicase domain protein; KEGG: rsp:RSP_2422 ATP-dependent helicase, MgpS YP_915622.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: rsp:RSP_2421 hypothetical protein YP_915623.1 PFAM: Sterol-binding domain protein; KEGG: jan:Jann_3313 sterol-binding YP_915624.1 PFAM: alpha/beta hydrolase fold; KEGG: sil:SPO1414 hydrolase, alpha/beta fold family YP_915625.1 TIGRFAM: oligoendopeptidase, pepF/M3 family; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; Oligopeptidase F; KEGG: rsp:RSP_2412 oligoendopeptidase F YP_915626.1 PFAM: peptidase M19, renal dipeptidase; KEGG: sit:TM1040_0564 peptidase M19, renal dipeptidase YP_915627.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: atc:AGR_C_1530 structure of glutathione S-transferase III in apo form YP_915628.1 PFAM: protein of unknown function DUF344; KEGG: rsp:RSP_0766 hypothetical protein YP_915629.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_915630.1 PFAM: protein of unknown function UPF0060; KEGG: mag:amb3269 hypothetical protein YP_915631.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: cch:Cag_0961 phosphoesterase, PA-phosphatase related YP_915632.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_0776 ABC lipoprotein efflux transporter, ATPase subunit, LolD YP_915633.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: sit:TM1040_1846 lipoprotein releasing system, transmembrane protein, LolC/E family YP_915634.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: sit:TM1040_2537 cytochrome oxidase maturation protein, cbb3-type YP_915635.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: rsp:RSP_0690 copper-translocating P-type ATPase, RdxI YP_915636.1 PFAM: FixH family protein; KEGG: rsp:RSP_0691 RdxH YP_915637.1 TIGRFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: rsp:RSP_0692 iron-sulfur cluster-binding protein YP_915638.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I; KEGG: rsp:RSP_0693 Cbb3-type cytochrome c oxidase CcoP subunit YP_915639.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: sit:TM1040_2543 Cbb3-type cytochrome oxidase component YP_915640.1 CcoO; FixO YP_915641.1 CcoN; FixN YP_915642.1 PFAM: UspA domain protein; KEGG: sil:SPO3527 universal stress protein family protein YP_915643.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: rde:RD1_1268 transcriptional activator protein FnrL YP_915644.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_915645.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: sil:SPO1387 cation efflux system protein YP_915646.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_915647.1 KEGG: rsp:RSP_1027 hypothetical protein YP_915648.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPO3847 ABC transporter, ATP-binding protein YP_915649.1 PFAM: histidine triad (HIT) protein; KEGG: rsp:RSP_1029 possible histidine triad (HIT) protein YP_915650.1 PFAM: glycosyl transferase, family 14; KEGG: sil:SPO3319 EpsK domain protein YP_915651.1 KEGG: sit:TM1040_2487 conserved hypothetical protein YP_915652.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_915653.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_915654.1 KEGG: rsp:RSP_2612 3-oxoacyl-(acyl-carrier-protein) synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YP_915655.1 PFAM: zinc finger, DksA/TraR C4-type; KEGG: sil:SPO1411 C4-type zinc finger protein, DksA/TraR family YP_915656.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_915657.1 PFAM: regulatory protein, MerR; KEGG: sil:SPO2496 transcriptional regulator, MerR family YP_915658.1 Catalyzes the deamination of dCTP to form dUTP YP_915659.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: rsp:RSP_2939 predicted transcriptional regulator containing the HTH domain YP_915660.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: rde:RD1_3162 hypothetical protein YP_915661.1 PFAM: glycoside hydrolase, family 3 domain protein; KEGG: rsp:RSP_2941 glycoside hydrolase YP_915662.1 PFAM: Sporulation domain protein; KEGG: rde:RD1_3164 hypothetical protein YP_915663.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_915664.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_915665.1 PFAM: heat shock protein DnaJ domain protein; KEGG: rsp:RSP_1978 molecular chaperone, DnaJ family YP_915666.1 PFAM: BolA family protein; KEGG: sil:SPO2849 BolA protein, truncation YP_915667.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_915668.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: rsp:RSP_0405 probable single-stranded DNA-specific exonuclease YP_915670.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_915671.1 PFAM: Uncharacterized protein UPF0114; KEGG: ccr:CC1036 hypothetical protein YP_915672.1 PFAM: protein of unknown function DUF710; KEGG: rde:RD1_2980 hypothetical protein YP_915673.1 KEGG: rde:RD1_2981 hypothetical protein YP_915674.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_915675.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_915676.1 KEGG: rsp:RSP_2244 hypothetical protein YP_915677.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_915678.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_915679.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_915680.1 PFAM: MgtC/SapB transporter; KEGG: mes:Meso_3446 MgtC/SapB transporter YP_915681.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: rsp:RSP_1971 ribonuclease D YP_915682.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_915683.1 KEGG: rsp:RSP_2618 hemolysin YP_915684.1 KEGG: sme:SMc00117 peptide methionine sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B YP_915685.1 KEGG: rsp:RSP_2616 hypothetical protein YP_915686.1 PFAM: protein of unknown function DUF177; KEGG: rsp:RSP_2615 hypothetical protein YP_915687.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_915688.1 catalyzes the formation of betaine from betaine aldehyde YP_915689.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_915690.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: sme:SMc02737 glycine betaine-binding ABC transporter protein YP_915691.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_2180 ABC glycine betaine/L-proline transporter, inner membrane subunit YP_915692.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2179 ABC glycine betaine/L-proline tranporter, ATPase subunit, ProV YP_915693.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: rsp:RSP_0654 possible transporter, DMT superfamily YP_915694.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: rru:Rru_A0657 lysine exporter protein (LysE/YggA) YP_915695.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_915696.1 PFAM: protein of unknown function DUF28; KEGG: rsp:RSP_0655 hypothetical protein YP_915697.1 KEGG: mes:Meso_1983 hypothetical protein YP_915698.1 KEGG: rsp:RSP_2137 hypothetical protein YP_915699.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_915700.1 PFAM: protein of unknown function DUF1321; KEGG: rsp:RSP_2139 hypothetical protein YP_915701.1 KEGG: mes:Meso_3101 PRC-barrel YP_915702.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_915703.1 KEGG: rsp:RSP_4041 tyrosyl-tRNA synthetase, class Ib; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib; RNA-binding S4 domain protein YP_915704.1 KEGG: mlo:mll5005 hypothetical protein YP_915705.1 PFAM: protein of unknown function DUF188; KEGG: rde:RD1_0321 YaiI/YqxD family protein YP_915706.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: rsp:RSP_4042 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_915707.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: sit:TM1040_1085 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_915708.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_915710.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_915711.1 KEGG: rsp:RSP_1843 signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_915712.1 KEGG: rsp:RSP_2037 hypothetical protein YP_915713.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_915714.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_915715.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_915716.1 KEGG: rde:RD1_4066 hypothetical protein YP_915717.1 KEGG: rsp:RSP_1985 hypothetical protein YP_915718.1 PFAM: cell wall hydrolase, SleB; KEGG: rsp:RSP_2496 hypothetical protein YP_915719.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_915720.1 KEGG: rsp:RSP_6052 hypothetical protein YP_915721.1 PFAM: protein of unknown function DUF541; KEGG: rsp:RSP_2430 hypothetical protein YP_915722.1 KEGG: sit:TM1040_0585 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_915723.1 KEGG: rsp:RSP_7183 translation initiation factor 2, gamma subunit, GTPase YP_915724.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_915725.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism YP_915726.1 PFAM: cytochrome c, class I; KEGG: sil:SPO0130 cytochrome c family protein YP_915727.1 PFAM: cytochrome c oxidase, subunit I; KEGG: rsp:RSP_1877 cytochrome c oxidase, aa3 type, subunit I YP_915728.1 KEGG: rsp:RSP_1876 hypothetical protein YP_915729.1 PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: rsp:RSP_3566 dimethylglycine dehydrogenase YP_915730.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: jan:Jann_0915 glycolate reductase YP_915731.1 PFAM: protein of unknown function DUF1058; KEGG: rsp:RSP_2312 hypothetical protein YP_915732.1 KEGG: syw:SYNW2410 hypothetical protein YP_915733.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: rsp:RSP_0596 peptidyl-dipeptidase YP_915734.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: rsp:RSP_0597 probable molybdopterin biosynthesis protein YP_915735.1 KEGG: sil:SPO0409 deoxyuridine 5'-triphosphate nucleotidohydrolase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase YP_915736.1 KEGG: sit:TM1040_0184 conserved hypothetical protein YP_915737.1 KEGG: rsp:RSP_3072 L-sorbosone dehydrogenase YP_915738.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_915739.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: rsp:RSP_2735 6-phosphogluconolactonase YP_915740.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_915741.1 KEGG: jan:Jann_2688 hypothetical protein YP_915742.1 KEGG: rsp:RSP_2647 predicted SAM-dependent methyltransferase YP_915743.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_915744.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold domain protein; KEGG: mca:MCA2070 sensory box protein YP_915745.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: rsp:RSP_0630 hypothetical protein YP_915746.1 PFAM: Uncharacterized conserved protein UCP032146; KEGG: rde:RD1_1069 hypothetical protein YP_915747.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_915748.1 KEGG: sit:TM1040_3566 conserved hypothetical protein YP_915749.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_915750.1 KEGG: mca:MCA2639 hypothetical protein YP_915751.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: sme:SMc02151 hypothetical virulence associated protein homologue YP_915752.1 KEGG: shm:Shewmr7_0348 hypothetical protein YP_915753.1 KEGG: mes:Meso_4610 hypothetical protein YP_915757.1 KEGG: bxe:Bxe_A0083 hypothetical protein YP_915758.1 KEGG: psp:PSPPH_0608 pancortin-3 YP_915759.1 KEGG: bja:blr1827 transposase YP_915760.1 PFAM: Resolvase, N-terminal domain; Recombinase; KEGG: nha:Nham_3864 recombinase YP_915761.1 KEGG: rsp:RSP_3837 hypothetical protein YP_915762.1 KEGG: mag:amb1768 Mu-like prophage major head subunit gpT YP_915766.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rsp:RSP_1663 transcriptional regulator, LacI family YP_915767.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: rsp:RSP_0923 methionine aminopeptidase, subfamily 1 YP_915768.1 PFAM: molybdopterin binding domain; KEGG: sit:TM1040_2467 molybdopterin binding domain YP_915769.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_0925 acetyl transferase YP_915770.1 KEGG: sit:TM1040_2681 conserved hypothetical protein YP_915771.1 KEGG: sil:SPO3814 hypothetical protein YP_915772.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_915773.1 PFAM: transcriptional coactivator/pterin dehydratase; KEGG: mca:MCA0497 pterin-4-alpha-carbinolamine dehydratase YP_915774.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: rba:RB9533 cardiolipin synthase YP_915775.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit; KEGG: sit:TM1040_2676 acetyl-CoA carboxylase, carboxyl transferase, beta subunit YP_915776.1 KEGG: rsp:RSP_0930 folylpolyglutamate synthetase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle domain protein YP_915777.1 PFAM: AFG1-family ATPase; KEGG: rsp:RSP_1349 hypothetical protein YP_915778.1 KEGG: jan:Jann_2690 hypothetical protein YP_915779.1 PFAM: aldehyde dehydrogenase; KEGG: rme:Rmet_0158 aldehyde dehydrogenase YP_915780.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: atc:AGR_C_4107 hypothetical protein YP_915781.1 KEGG: ade:Adeh_0560 hypothetical protein YP_915782.1 KEGG: hsa:729099 hypothetical protein LOC729099 YP_915783.1 PFAM: HemY domain protein; KEGG: rsp:RSP_1508 uncharacterized HemY-like membrane protein YP_915784.1 KEGG: jan:Jann_4082 hypothetical protein YP_915785.1 KEGG: rsp:RSP_6208 uroporphyrinogen-III synthase YP_915786.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_915787.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_915788.1 PFAM: YCII-related; KEGG: rsp:RSP_1511 hypothetical protein YP_915789.1 PFAM: protein of unknown function DUF55; KEGG: rsp:RSP_1512 hypothetical protein YP_915790.1 KEGG: rsp:RSP_2254 ABC efflux transporter, fused ATPase and inner membrane subunits; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_915791.1 PFAM: Allergen V5/Tpx-1 family protein; KEGG: fra:Francci3_3457 allergen V5/TPX-1 related YP_915792.1 PFAM: Peptidoglycan-binding LysM; transport-associated; KEGG: sil:SPO3004 LysM/phospholipid-binding domain protein YP_915793.1 activates fatty acids by binding to coenzyme A YP_915794.1 KEGG: sit:TM1040_2837 conserved hypothetical protein YP_915795.1 KEGG: sil:SPO3503 hypothetical protein YP_915796.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_915797.1 PFAM: sulfotransferase; KEGG: syg:sync_0226 hypothetical protein YP_915798.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_915801.1 PFAM: ABC-2 type transporter; KEGG: sit:TM1040_2524 ABC-2 type transporter YP_915802.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: jan:Jann_0746 ABC transporter related YP_915803.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: rde:RD1_1601 acyltransferase YP_915804.1 PFAM: protein of unknown function DUF214; KEGG: rsp:RSP_0734 cell division protein FtsX YP_915805.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPO0337 cell division ATP-binding protein FtsE YP_915806.1 TIGRFAM: MJ0042 family finger-like protein; KEGG: rsp:RSP_0732 hypothetical protein YP_915807.1 KEGG: rsp:RSP_0730 hypothetical protein YP_915808.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: rsp:RSP_0729 Orn/DAP/Arg decarboxylase, family 2 YP_915809.1 KEGG: rsp:RSP_0728 hypothetical protein YP_915810.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_915811.1 PFAM: Redoxin domain protein; Thioredoxin domain; KEGG: rsp:RSP_0725 thioredoxin, thioldisulfide interchange protein YP_915812.1 KEGG: rsp:RSP_0744 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_915813.1 PFAM: EAL domain protein; KEGG: jan:Jann_0494 diguanylate phosphodiesterase YP_915814.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_915815.1 TIGRFAM: acetoacetyl-CoA reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: rsp:RSP_0747 short-chain dehydrogenase/reductase YP_915816.1 PFAM: protein of unknown function DUF465; KEGG: rde:RD1_3398 hypothetical protein YP_915817.1 PFAM: methyltransferase small; Methyltransferase type 11; KEGG: rsp:RSP_0748 N-6 adenine-specific DNA methylase YP_915818.1 KEGG: rsp:RSP_0749 hypothetical protein YP_915819.1 PFAM: Polyprenyl synthetase; KEGG: sit:TM1040_3742 farnesyltranstransferase YP_915820.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: mca:MCA2136 ammonium transporter YP_915821.1 KEGG: rsp:RSP_0887 glycosyl transferase, family 51; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_915822.1 PFAM: toluene tolerance family protein; KEGG: rsp:RSP_0890 possible protein YrbC precursor YP_915823.1 PFAM: VacJ family lipoprotein; KEGG: sil:SPO3727 VacJ lipoprotein YP_915824.1 KEGG: rsp:RSP_0892 ABC protein toxin exporter, fused ATPase and inner membrane domain; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase YP_915825.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: rsp:RSP_0893 RTX secretion protein D, HlyD family YP_915827.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_915828.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mlo:mll5006 aminoglycoside 6'-N-acetyltransferase YP_915829.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_915830.1 PFAM: ABC-2 type transporter; KEGG: sil:SPO0957 ABC transporter, permease protein YP_915831.1 PFAM: GcrA cell cycle regulator; KEGG: rsp:RSP_2007 conservd hypothetical protein YP_915832.1 PFAM: NUDIX hydrolase; KEGG: sit:TM1040_3067 NUDIX hydrolase YP_915833.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_915834.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: atc:AGR_L_1858 outer membrane protein irgA precursor YP_915835.1 TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: rsp:RSP_2632 arginase YP_915842.1 KEGG: nha:Nham_2360 hypothetical protein YP_915844.1 KEGG: xft:PD1844 hypothetical protein YP_915846.1 KEGG: jan:Jann_0233 hypothetical protein YP_915847.1 KEGG: nar:Saro_2759 transposase orfA IS5 family element YP_915848.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: reu:Reut_A0008 HNH endonuclease YP_915849.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: jan:Jann_2858 DNA-cytosine methyltransferase YP_915850.1 PFAM: DNA mismatch endonuclease vsr; KEGG: dvu:DVU2843 DNA mismatch endonuclease Vsr YP_915851.1 KEGG: son:SO2967 hypothetical phage terminase large subunit YP_915852.1 TIGRFAM: phage terminase, small subunit, , P27 family; PFAM: phage terminase, small subunit, , P27; KEGG: dvu:DVU1504 terminase, small subunit YP_915853.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: rsp:RSP_3621 cold-shock DNA-binding protein YP_915854.1 KEGG: rsp:RSP_3622 hypothetical protein YP_915855.1 KEGG: mag:amb1162 hypothetical protein YP_915856.1 PFAM: DNA methylase N-4/N-6 domain protein; ParB domain protein nuclease; KEGG: mag:amb0363 modification methylase DpnIIB YP_915857.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: rso:RSc1680 probable phage PHI-105 holin-like protein YP_915858.1 KEGG: hch:HCH_05683 hypothetical protein YP_915859.1 KEGG: mag:amb0360 hypothetical protein YP_915860.1 KEGG: ade:Adeh_1681 PE-PGRS family protein YP_915862.1 KEGG: bbr:BB2472 plasmid stability protein YP_915863.1 PFAM: PilT protein domain protein; KEGG: gox:GOX2696 plasmid stabilization protein YP_915864.1 KEGG: mxa:MXAN_1879 hypothetical protein YP_915866.1 KEGG: rso:RSc3240 hypothetical protein YP_915868.1 KEGG: nwi:Nwi_1952 hypothetical protein YP_915869.1 PFAM: Resolvase, N-terminal domain; Recombinase; KEGG: nwi:Nwi_1951 resolvase YP_915870.1 KEGG: nwi:Nwi_2834 hypothetical protein YP_915871.1 KEGG: rsp:RSP_3808 hypothetical protein YP_915873.1 KEGG: nar:Saro_2176 hypothetical protein YP_915874.1 PFAM: Ankyrin; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: tpa:TP0493 RNA polymerase sigma-70 factor YP_915875.1 KEGG: rfr:Rfer_3071 hypothetical protein YP_915876.1 KEGG: rfr:Rfer_3072 endonuclease YP_915877.1 KEGG: rfr:Rfer_3073 hypothetical protein YP_915878.1 KEGG: rfr:Rfer_3074 hypothetical protein YP_915880.1 PFAM: transposase, IS4 family protein; KEGG: sil:SPOA0134 ISSpo7, transposase YP_915881.1 KEGG: rsp:RSP_1461 3-deoxy-D-manno-octulosonic-acid transferase YP_915882.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_915883.1 PFAM: DSBA oxidoreductase; KEGG: sit:TM1040_2643 thiol:disulfide interchange protein, DsbA family YP_915884.1 PFAM: protein of unknown function DUF1159; KEGG: rsp:RSP_1465 hypothetical protein YP_915885.1 PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: rsp:RSP_1466 MutY, A/G-specific adenine glycosylase YP_915886.1 PFAM: fatty acid desaturase; KEGG: sit:TM1040_2646 alkane-1 monooxygenase YP_915888.1 KEGG: jan:Jann_1007 hypothetical protein YP_915889.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rsp:RSP_1468 site-specific DNA-methyltransferase YP_915890.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_915891.1 PFAM: Ureidoglycolate hydrolase; KEGG: sit:TM1040_3474 ureidoglycolate hydrolase YP_915892.1 PFAM: major facilitator superfamily MFS_1; KEGG: mlo:mlr2687 probable fosmidomycin resistance protein YP_915893.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: sil:SPO1369 transcriptional regulator, GntR family YP_915894.1 PFAM: Peptidoglycan-binding domain 1 protein; ErfK/YbiS/YcfS/YnhG family protein; KEGG: ret:RHE_CH01741 hypothetical protein YP_915895.1 PFAM: Extensin family protein; KEGG: sme:SMc02727 hypothetical protein YP_915896.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: mlo:mll3135 transcriptional regulator, Fnr-type YP_915897.1 KEGG: rsp:RSP_1332 H+-transporting two-sector ATPase, alpha/beta subunit; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; SMART: AAA ATPase YP_915898.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_915899.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_915900.1 PFAM: flagellar hook-basal body complex protein FliE; KEGG: rsp:RSP_1329 flagellar hook-basal body complex protein YP_915901.1 PFAM: export protein FliQ, family 3; KEGG: rsp:RSP_1328 flagellar biosynthetic protein FliQ YP_915902.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Rhodobacter sphaeroides has 2 copies of this and other flagella genes YP_915903.1 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella YP_915904.1 required for the assembly of the flagellar basal body P-ring YP_915905.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_915906.1 KEGG: jan:Jann_4190 hypothetical protein YP_915907.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sit:TM1040_3859 glucose-1-phosphate thymidylyltransferase YP_915908.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: rde:RD1_B0018 dTDP-4-dehydrorhamnose reductase YP_915909.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: rde:RD1_B0019 dTDP-glucose 4,6-dehydratase YP_915910.1 KEGG: sit:TM1040_3863 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_915912.1 PFAM: Hemolysin-type calcium-binding region; KEGG: ter:Tery_2034 RTX toxins and related Ca2+-binding protein YP_915913.1 PFAM: ABC-2 type transporter; KEGG: sme:SMb20833 cell surface polysaccharide export ABC-2 transporter permease protein, close relative of Y20822wzm2 YP_915914.1 KEGG: mes:Meso_2756 capsule polysaccharide export protein-like YP_915915.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20832 cell surface polysaccharide export ABC-2 transporter ATP-binding protein YP_915916.1 PFAM: protein of unknown function DUF1486; KEGG: rsp:RSP_0629 hypothetical protein YP_915917.1 KEGG: rsp:RSP_0628 hypothetical protein YP_915918.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: rsp:RSP_0627 amidohydrolase YP_915919.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bbr:BB0980 GnaT-family acetyltransferase YP_915920.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_915921.1 KEGG: rsp:RSP_2005 possible peptidyl-prolyl cis-trans isomerse YP_915922.1 PFAM: aminotransferase, class V; aminotransferase, class I and II; KEGG: rsp:RSP_2341 hypothetical protein YP_915923.1 KEGG: cel:ZK84.1 Hypothetical protein ZK84.1 YP_915924.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: rsp:RSP_2002 anthranilate synthase component II YP_915925.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_915926.1 TIGRFAM: uracil-DNA glycosylase; PFAM: Uracil-DNA glycosylase superfamily; KEGG: sit:TM1040_1139 uracil-DNA glycosylase YP_915927.1 PFAM: Indole-3-glycerol phosphate synthase; KEGG: sil:SPO2151 indole-3-glycerol phosphate synthase YP_915928.1 TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: rsp:RSP_2000 molybdenum cofactor biosynthesis protein C YP_915929.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: rsp:RSP_1998 molybdenum cofactor biosynthesis protein A YP_915930.1 Represses a number of genes involved in the response to DNA damage YP_915931.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: rsp:RSP_0550 D-alanyl-D-alanine carboxypeptidase YP_915932.1 PFAM: thymidylate kinase; KEGG: sil:SPO2740 thymidylate kinase YP_915933.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_915934.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; amidohydrolase 2; KEGG: rsp:RSP_0675 TatD-related deoxyribonuclease YP_915935.1 PFAM: beta-lactamase domain protein; KEGG: rsp:RSP_0676 PhnP-like protein YP_915936.1 PFAM: Auxin Efflux Carrier; KEGG: rsp:RSP_0677 malonate transporter, MdcF, AEC family YP_915937.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_1886 ABC polyamine/opine transporter, inner membrane subunit YP_915938.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_1884 ABC polyamine/opine transporter, inner membrane subunit YP_915939.1 KEGG: sil:SPO3473 polyamine ABC trasnporter, periplasmic polyamine-binding protein YP_915940.1 PFAM: extracellular solute-binding protein, family 1; KEGG: rsp:RSP_0161 spermidine/putrescine-binding periplasmic protein YP_915941.1 KEGG: rsp:RSP_1882 ABC polyamine/opine transporter, ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_915942.1 PFAM: protein of unknown function DUF421; KEGG: rsp:RSP_1130 hypothetical membrane protein YP_915943.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: atc:AGR_L_1073 short chain dehydrogenase YP_915944.1 TIGRFAM: FGGY-family pentulose kinase; PFAM: carbohydrate kinase, FGGY; KEGG: atc:AGR_L_1075 D-ribulokinase YP_915945.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: atc:AGR_L_1076 ribitol 2-dehydrogenase YP_915946.1 PFAM: inner-membrane translocator; KEGG: atc:AGR_L_1078 ribose ABC transporter (permease) YP_915947.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atu:Atu4321 ABC transporter, nucleotide binding/ATPase protein [ribose] YP_915948.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: atc:AGR_L_1084 periplasmic ribose-binding protein of ABC transport system YP_915949.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: atc:AGR_L_1086 hypothetical protein YP_915950.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY; KEGG: mlo:mlr5033 xylulokinase YP_915951.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_L_1091 xylitol dehydrogenase YP_915952.1 PFAM: GatB/Yqey domain protein; KEGG: rsp:RSP_1875 hypothetical protein YP_915953.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_915954.1 PFAM: glycosyl transferase, family 2; General secretory system II, protein E domain protein; KEGG: rsp:RSP_1872 glycosyl transferase, family 2 YP_915955.1 PFAM: glutamate-ammonia ligase adenylyltransferase; KEGG: rsp:RSP_2643 glutamate-ammonia-ligase adenylyltransferase YP_915956.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_915957.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: sit:TM1040_0875 acetolactate synthase, large subunit, biosynthetic type YP_915958.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_915959.1 KEGG: rde:RD1_2814 hypothetical protein YP_915960.1 PFAM: peptidase M48, Ste24p; KEGG: rde:RD1_1656 peptidase, M48 family YP_915961.1 KEGG: rsp:RSP_6045 hypothetical protein YP_915962.1 PFAM: protein of unknown function DUF167; KEGG: sil:SPO0937 hypothetical protein YP_915963.1 PFAM: nitroreductase; KEGG: jan:Jann_3161 nitroreductase YP_915964.1 KEGG: rsp:RSP_0810 hypothetical protein YP_915965.1 PFAM: protein of unknown function DUF1467; KEGG: rsp:RSP_0811 hypothetical protein YP_915966.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sit:TM1040_0637 glyoxalase/bleomycin resistance protein/dioxygenase YP_915967.1 PFAM: response regulator receiver; KEGG: sil:SPO0931 response regulator YP_915968.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_0814 acetyltransferase YP_915969.1 PFAM: protein of unknown function DUF1501; KEGG: ret:RHE_CH02550 hypothetical protein YP_915970.1 KEGG: ret:RHE_CH02551 hypothetical protein YP_915971.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_915972.1 PFAM: Abortive infection protein; KEGG: pat:Patl_3840 abortive infection protein YP_915973.1 PFAM: glycoside hydrolase, family 25; KEGG: sil:SPO3258 glycosyl hydrolase, family 25 YP_915975.1 PFAM: FAD linked oxidase domain protein; KEGG: rsp:RSP_2120 D-lactate dehydrogenase (cytochrome), FAD/FMN-containing oxidoreductase YP_915976.1 PFAM: protein of unknown function DUF808; KEGG: jan:Jann_1699 protein of unknown function DUF808 YP_915977.1 KEGG: rsp:RSP_1977 cobalt chelatase, CobS small subunit; TIGRFAM: cobalt chelatase, pCobS small subunit; PFAM: ATPase associated with various cellular activities, AAA_5 YP_915979.1 KEGG: rde:RD1_3340 aerobic cobaltochelatase CobT subunit; TIGRFAM: cobalt chelatase, pCobT subunit; PFAM: Cobalt chelatase, CobT subunit; SMART: von Willebrand factor, type A YP_915980.1 PFAM: glycosyl transferase, group 1; KEGG: mxa:MXAN_7445 glycosyl transferase, group 1 family protein YP_915981.1 PFAM: peptidase M24; KEGG: rsp:RSP_1975 aminopeptidase P YP_915982.1 PFAM: protein of unknown function DUF475; KEGG: rsp:RSP_0459 hypothetical protein YP_915983.1 PFAM: MOFRL domain protein; KEGG: sit:TM1040_3471 hydroxypyruvate reductase YP_915984.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: sil:SPO0913 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_915985.1 TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein; KEGG: rsp:RSP_3365 protein secretion chaperonine YP_915986.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_915987.1 KEGG: jan:Jann_3330 hypothetical protein YP_915988.1 PFAM: aminotransferase, class I and II; KEGG: rsp:RSP_0789 aminotransferase, class-I YP_915989.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_915990.1 KEGG: rsp:RSP_1571 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_915991.1 PFAM: protein of unknown function DUF465; KEGG: jan:Jann_3351 protein of unknown function DUF465 YP_915992.1 KEGG: jan:Jann_2350 hypothetical protein YP_915993.1 PFAM: heat shock protein Hsp20; KEGG: jan:Jann_3350 heat shock protein HSP20 YP_915994.1 PFAM: protein of unknown function DUF1150; KEGG: rsp:RSP_1573 hypothetical protein YP_915995.1 KEGG: rsp:RSP_1575 binfunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein YP_915996.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: rsp:RSP_1576 thioredoxin reductase YP_915997.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: rsp:RSP_1577 proline dehydrogenase transcriptional activator YP_915999.1 PFAM: protein of unknown function DUF152; KEGG: rde:RD1_3503 hypothetical protein YP_916000.1 PFAM: protein of unknown function DUF185; KEGG: sil:SPO0907 hypothetical protein YP_916001.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_916002.1 PFAM: protein of unknown function DUF526; KEGG: sit:TM1040_0621 protein of unknown function DUF526 YP_916003.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; KEGG: rsp:RSP_2409 pseudouridine synthase, Rlu YP_916004.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_916005.1 KEGG: rsp:RSP_6009 hypothetical protein YP_916006.1 PFAM: Sporulation domain protein; KEGG: rsp:RSP_6008 hypothetical protein YP_916007.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_916008.1 catalyzes the formation of inosine from adenosine YP_916009.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_916010.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_916011.1 TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: sil:SPO2930 cytidine deaminase YP_916012.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate YP_916013.1 PFAM: AMP-dependent synthetase and ligase; KEGG: rsp:RSP_1592 possible acyl-CoA sythetase YP_916014.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_916015.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_916016.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: rsp:RSP_2534 predicted hydrolase of the metallo-beta-lactamase superfamily YP_916017.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_916018.1 KEGG: sil:SPO2762 biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase YP_916019.1 Catalyzes the transfer of electrons from NADH to quinone YP_916020.1 Catalyzes the transfer of electrons from NADH to quinone YP_916021.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_916022.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L; KEGG: sit:TM1040_0757 NADH-ubiquinone oxidoreductase, chain 4L YP_916023.1 Catalyzes the transfer of electrons from NADH to quinone YP_916024.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: rsp:RSP_2524 possible carboxymuconolactone decarboxylase family protein YP_916025.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: jan:Jann_1188 carboxymuconolactone decarboxylase YP_916026.1 Catalyzes the transfer of electrons from NADH to quinone YP_916027.1 Catalyzes the transfer of electrons from NADH to quinone YP_916028.1 KEGG: jan:Jann_1184 lipoprotein YP_916029.1 Catalyzes the transfer of electrons from NADH to quinone YP_916030.1 KEGG: sil:SPO2775 hypothetical protein YP_916031.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_916032.1 KEGG: jan:Jann_1178 hypothetical protein YP_916033.1 KEGG: jan:Jann_1177 hypothetical protein YP_916034.1 Catalyzes the transfer of electrons from NADH to quinone YP_916035.1 Catalyzes the transfer of electrons from NADH to quinone YP_916036.1 Catalyzes the transfer of electrons from NADH to quinone YP_916037.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_916038.1 Catalyzes the transfer of electrons from NADH to quinone YP_916039.1 KEGG: sit:TM1040_0660 conserved hypothetical protein YP_916040.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_916041.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: atc:AGR_C_4363 hypothetical protein YP_916042.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_916043.1 KEGG: rsp:RSP_6106 hypothetical protein YP_916044.1 KEGG: sil:SPO2798 hypothetical protein YP_916045.1 KEGG: rsp:RSP_1012 succinate-semialdehyde dehdyrogenase; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_916046.1 PFAM: protein of unknown function DUF1013; KEGG: rsp:RSP_0714 hypothetical protein YP_916047.1 PFAM: ribonuclease T2; KEGG: sit:TM1040_2631 ribonuclease T2 YP_916049.1 PFAM: TM2 domain containing protein+B7201; KEGG: pau:PA14_53630 hypothetical protein YP_916050.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_916052.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: bxe:Bxe_A3350 glutathione S-transferase YP_916053.1 TIGRFAM: large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel; KEGG: sil:SPO3495 large conductance mechanosensitive channel protein YP_916054.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: rsp:RSP_0722 transcriptional regulator, AsnC family YP_916055.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_916056.1 TIGRFAM: rpsU-divergently transcribed protein; PFAM: COQ9 domain protein; KEGG: sil:SPO0230 hypothetical protein YP_916057.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rsp:RSP_0716 NADPH/quinone reductase and related Zn-dependent oxidoreductase YP_916058.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_916059.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: hne:HNE_0991 arsenate reductase YP_916060.1 PFAM: cytochrome P450; KEGG: rde:RD1_1394 cytochrome P450 YP_916061.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_916062.1 PFAM: ribosomal protein L35; KEGG: rsp:RSP_1765 50S ribosomal protein L35 YP_916064.1 PFAM: pyruvate kinase; KEGG: sil:SPO3600 pyruvate kinase YP_916065.1 PFAM: N-formylglutamate amidohydrolase; KEGG: rsp:RSP_1767 possible N-formylglutamate amidohydrolase YP_916069.1 PFAM: Arc domain protein DNA binding domain protein YP_916070.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: mca:MCA1751 hypothetical protein YP_916072.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: atc:AGR_L_470 hypothetical protein YP_916073.1 PFAM: sulfatase; KEGG: rsp:RSP_0594 choline sulfatase YP_916074.1 PFAM: membrane protein of uknown function UCP014873; KEGG: gvi:gll1598 hypothetical protein YP_916075.1 TIGRFAM: monofunctional biosynthetic peptidoglycan transglycosylase; PFAM: glycosyl transferase, family 51; KEGG: sil:SPO3766 monofunctional biosynthetic peptidoglycan transglycosylase YP_916076.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: jan:Jann_0275 glutathione S-transferase-like YP_916077.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: rsp:RSP_1143 4Fe-4S ferredoxin, iron-sulfur cluster binding protein YP_916078.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: rsp:RSP_0987 transporter, RarD family, DMT superfamily YP_916079.1 KEGG: sit:TM1040_0020 conserved hypothetical protein YP_916080.1 PFAM: glycosyl transferase, family 14; KEGG: sit:TM1040_0019 glycosyl transferase, family 14 YP_916081.1 KEGG: jan:Jann_0220 hypothetical protein YP_916082.1 PFAM: glycosyl transferase, group 1; KEGG: jan:Jann_0219 glycosyl transferase, group 1 YP_916083.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; KEGG: sit:TM1040_0016 UDP-glucose 4-epimerase YP_916084.1 PFAM: Nucleotidyl transferase; KEGG: rsp:RSP_1159 UDP-glucose pyrophosphate YP_916085.1 PFAM: glycosyl transferase, family 2; KEGG: jan:Jann_0217 glycosyl transferase, family 2 YP_916086.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_916087.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: rsp:RSP_1161 3'-phosphadenosine 5'-phosphosulfate 3'-phosphatase YP_916088.1 PFAM: ABC-2 type transporter; KEGG: sil:SPO0040 ABC transporter, permease protein YP_916089.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_916090.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_916091.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_916092.1 TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: sit:TM1040_2814 ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_916093.1 PFAM: Cytochrome b/b6, N-terminal domain; Cytochrome b/b6, C-terminal domain; KEGG: sit:TM1040_2813 cytochrome b/b6-like YP_916094.1 PFAM: cytochrome c1; KEGG: rde:RD1_0565 cytochrome c1 YP_916095.1 PFAM: PfkB domain protein; KEGG: rsp:RSP_1216 RbsK, carbohydrate kinase, ribokinase family YP_916096.1 PFAM: peptidase S49; KEGG: sil:SPO3640 peptidase, family S49 YP_916098.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: jan:Jann_3920 short-chain dehydrogenase/reductase SDR YP_916099.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_916100.1 KEGG: atc:AGR_C_2408 hypothetical protein YP_916101.1 KEGG: rsp:RSP_2812 hypothetical protein YP_916102.1 PFAM: Mammalian cell entry related domain protein; KEGG: rsp:RSP_2811 ABC transporter, periplasmic substrate-binding protein YP_916103.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2810 ABC transporter, ATPase subunit YP_916104.1 PFAM: protein of unknown function DUF140; KEGG: rsp:RSP_2809 ABC transporter, inner membrane subunit YP_916105.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: jan:Jann_1027 transcriptional regulator, LysR family YP_916106.1 TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: rsp:RSP_2172 5,10-methylenetetrahydrofolate reductase YP_916107.1 KEGG: sil:SPO3018 hypothetical protein YP_916108.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: rsp:RSP_1991 ornithine decarboxylase YP_916109.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: rsp:RSP_1990 transcriptional regulator, AsnC family YP_916110.1 TIGRFAM: methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: rsp:RSP_0901 N-6 adenine-specific DNA methylase YP_916111.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rsp:RSP_0900 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_916112.1 PFAM: Redoxin domain protein; KEGG: sit:TM1040_2472 redoxin YP_916113.1 PFAM: helix-turn-helix, HxlR type; KEGG: bpa:BPP3401 transcriptional regulator YP_916114.1 PFAM: protein of unknown function DUF1428; KEGG: hne:HNE_1019 hypothetical protein YP_916115.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc04054 hypothetical protein YP_916116.1 PFAM: YceI family protein; KEGG: bma:BMAA0007 YceI like family protein YP_916117.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bja:blr5350 glutathione S-transferase YP_916118.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_916119.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: sil:SPO2745 hypothetical protein YP_916120.1 KEGG: sil:SPOA0324 hypothetical protein YP_916121.1 PFAM: NnrUfamily protein; KEGG: rpe:RPE_1287 NnrU family protein YP_916122.1 PFAM: FAD dependent oxidoreductase; KEGG: jan:Jann_0139 FAD dependent oxidoreductase YP_916123.1 PFAM: protein of unknown function DUF752; KEGG: sil:SPO3553 hypothetical protein YP_916124.1 PFAM: Rhomboid family protein; KEGG: jan:Jann_3255 rhomboid-like protein YP_916125.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_916126.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_916127.1 PFAM: molybdopterin biosynthesis MoaE; KEGG: sit:TM1040_3633 molybdopterin biosynthesis MoaE YP_916128.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: sit:TM1040_3632 molybdopterin converting factor, subunit 1 YP_916129.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: rsp:RSP_1073 phosphatidylglycerol phosphate synthase YP_916130.1 PFAM: regulatory protein, MerR; KEGG: rsp:RSP_1790 probable transcriptional regulator YP_916131.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: rsp:RSP_1791 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_916132.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_916133.1 TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein; KEGG: rde:RD1_1223 glycine cleavage system H protein YP_916134.1 TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: rsp:RSP_2193 predicted aminomethyltransferase, tetrahydrofolate dependent YP_916135.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sil:SPO2692 oxidoreductase, short chain dehydrogenase/reductase family YP_916136.1 KEGG: rde:RD1_0883 hypothetical protein YP_916137.1 KEGG: rsp:RSP_2594 hypothetical protein YP_916138.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_2593 hybrid histidine kinase YP_916139.1 PFAM: domain of unknown function DUF1745; KEGG: rsp:RSP_2592 hypothetical protein YP_916140.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: rsp:RSP_2591 two component transcriptional regulator, LuxR family family YP_916141.1 KEGG: sme:SMb20181 ABC transporter periplasmic solute-binding protein YP_916142.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20182 ABC transporter protein YP_916143.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rde:RD1_0904 ABC transporter YP_916144.1 KEGG: rsp:RSP_2590 hypothetical protein YP_916145.1 KEGG: rde:RD1_1150 coenzyme PQQ biosynthesis protein E; TIGRFAM: coenzyme PQQ biosynthesis protein E; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_916146.1 PFAM: coenzyme PQQ synthesis D; KEGG: rde:RD1_1151 coenzyme PQQ synthesis protein D YP_916147.1 Required in the synthesis of PPQ, but its exact function is unknown YP_916148.1 possibly involved in transport of pyrroloquinoline quinone transport YP_916149.1 PFAM: beta-lactamase domain protein; KEGG: rsp:RSP_2589 hypothetical protein YP_916150.1 PFAM: alpha-2-macroglobulin domain protein; N/apple PAN domain protein; alpha-2-macroglobulin domain protein 2; Tetratricopeptide TPR_2 repeat protein; KEGG: rsp:RSP_1356 hypothetical protein YP_916151.1 PFAM: helix-turn-helix, Fis-type; GAF domain protein; KEGG: sit:TM1040_3622 GAF sensor protein YP_916152.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMc02689 probable aldehyde dehydrogenase protein YP_916153.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bmb:BruAb1_0198 alcohol dehydrogenase, zinc-containing YP_916154.1 PFAM: protein of unknown function DUF779; KEGG: mlo:mll6637 hypothetical protein YP_916155.1 PFAM: protein of unknown function DUF343; KEGG: sit:TM1040_0056 protein of unknown function DUF343 YP_916156.1 PFAM: peptidase S16, lon domain protein; KEGG: sit:TM1040_0055 peptidase S16, lon-like YP_916157.1 PFAM: Thioredoxin domain; KEGG: rsp:RSP_1489 protein containing thioredoxin domain YP_916158.1 TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sit:TM1040_0053 exodeoxyribonuclease III YP_916160.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: jan:Jann_0417 two component transcriptional regulator, winged helix family YP_916161.1 PFAM: GTP cyclohydrolase II; KEGG: jan:Jann_0416 GTP cyclohydrolase II YP_916162.1 KEGG: sil:SPO3428 hypothetical protein YP_916163.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: mes:Meso_2224 short-chain dehydrogenase/reductase SDR YP_916164.1 PFAM: RNA methylase; KEGG: sit:TM1040_2415 RNA methylase YP_916165.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mes:Meso_1284 glyoxalase/bleomycin resistance protein/dioxygenase YP_916166.1 PFAM: metallophosphoesterase; KEGG: rsp:RSP_0337 possible phospodiesterase YP_916167.1 PFAM: diacylglycerol kinase, catalytic region; KEGG: rsp:RSP_0338 hypothetical protein YP_916168.1 TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: tfu:Tfu_1872 isochorismate synthase YP_916169.1 PFAM: isochorismatase hydrolase; KEGG: bsu:BG11241 isochorismatase (2,3 dihydro-2,3 dihydroxybenzoate synthase) YP_916170.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KR; KEGG: hch:HCH_06575 short-chain alcohol dehydrogenase-like protein YP_916171.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_916172.1 PFAM: condensation domain protein; KEGG: bmb:BruAb2_0017 hypothetical enterobactin synthetase, component F YP_916173.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pfl:PFL_4020 acetyltransferase, GNAT family YP_916174.1 KEGG: hne:HNE_2962 hypothetical protein YP_916175.1 KEGG: hne:HNE_2963 hypothetical protein YP_916176.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: pol:Bpro_3190 cyclopropane-fatty-acyl-phospholipid synthase YP_916177.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_916178.1 KEGG: ret:RHE_PB00165 plasmid replication protein RepCb YP_916180.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: xfa:XF2071 conserved hypothetical protein YP_916182.1 KEGG: mlo:mlr9349 hypothetical protein YP_916187.1 PFAM: helix-turn-helix domain protein; KEGG: ngo:NGO0797 transcriptional regulator YP_916188.1 KEGG: ccr:CC1796 hypothetical protein YP_916189.1 KEGG: ccr:CC1796 hypothetical protein YP_916190.1 KEGG: mes:Meso_2004 D-alanine--D-alanine ligase; TIGRFAM: D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein YP_916191.1 PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: sil:SPO1183 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_916194.1 KEGG: bcl:ABC0984 hypothetical protein YP_916195.1 PFAM: outer membrane efflux protein; KEGG: spt:SPA2549 type I secretion protein YP_916196.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: ppu:PP_0803 protein secretion ABC efflux system, membrane fusion protein YP_916197.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: aeh:Mlg_2167 ABC transporter related YP_916199.1 PFAM: helix-turn-helix domain protein; KEGG: hne:HNE_0388 DNA-binding protein YP_916200.1 KEGG: sme:SMa2171 hypothetical protein YP_916201.1 PFAM: IS66 Orf2 family protein; KEGG: sme:SMa1613 hypothetical protein YP_916202.1 PFAM: phage integrase family protein; KEGG: sit:TM1040_1328 phage integrase YP_916203.1 PFAM: phage integrase family protein; KEGG: sit:TM1040_1328 phage integrase YP_916205.1 PFAM: helix-turn-helix domain protein YP_916207.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: sil:SPO2338 RarD YP_916208.1 KEGG: sil:SPO2330 hypothetical protein YP_916209.1 PFAM: Pyrrolo-quinoline quinone; KEGG: rsp:RSP_2698 quinoprotein YP_916210.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_916211.1 KEGG: sil:SPO1487 hypothetical protein YP_916212.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_916213.1 KEGG: rde:RD1_1508 SoxS YP_916214.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_916215.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: sil:SPO3311 ADA regulatory protein YP_916216.1 required for 70S ribosome assembly YP_916217.1 KEGG: mlo:mll2356 hypothetical protein YP_916218.1 KEGG: mlo:mll2355 hypothetical protein YP_916220.1 KEGG: mlo:mlr2353 hypothetical protein YP_916221.1 catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP YP_916222.1 KEGG: mlo:mlr2351 hypothetical protein YP_916223.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_3474 hypothetical protein YP_916224.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: rsp:RSP_3475 serine/threonine protein kinase YP_916225.1 PFAM: ImpA domain protein; KEGG: rsp:RSP_3476 hypothetical protein YP_916226.1 PFAM: Uncharacterized conserved protein UCP028301; KEGG: rsp:RSP_3477 hypothetical protein YP_916227.1 PFAM: protein of unknown function DUF877; KEGG: rsp:RSP_3478 hypothetical protein YP_916228.1 PFAM: protein of unknown function DUF796; KEGG: rsp:RSP_3479 hypothetical protein YP_916229.1 PFAM: protein of unknown function DUF1316; KEGG: rsp:RSP_3480 hypothetical protein YP_916230.1 PFAM: protein of unknown function DUF879; KEGG: rsp:RSP_3481 hypothetical protein YP_916231.1 PFAM: protein of unknown function DUF1305; KEGG: mlo:mlr2343 hypothetical protein YP_916232.1 PFAM: Forkhead-associated protein; KEGG: rsp:RSP_3483 FHA domain-containing protein YP_916233.1 KEGG: rsp:RSP_3484 hypothetical protein YP_916234.1 PFAM: protein of unknown function DUF876; KEGG: rsp:RSP_3485 hypothetical protein YP_916235.1 PFAM: OmpA/MotB domain protein; KEGG: rsp:RSP_3486 possible outer membrane protein, OmpA family YP_916236.1 PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: rsp:RSP_3487 hypothetical protein YP_916237.1 KEGG: rsp:RSP_3488 hypothetical protein YP_916238.1 PFAM: Rhs element Vgr protein; Gp5 domain protein; KEGG: rsp:RSP_3489 hypothetical protein YP_916239.1 PFAM: protein of unknown function DUF1215; KEGG: rsp:RSP_3490 hypothetical protein YP_916240.1 KEGG: rsp:RSP_3491 hypothetical protein YP_916241.1 PFAM: protein phosphatase 2C domain protein; Stage II sporulation E family protein; KEGG: rsp:RSP_3492 protein phosphatase 2C-like YP_916242.1 PFAM: OmpA/MotB domain protein; KEGG: rsp:RSP_3494 OmpA/MotB domain protein YP_916243.1 PFAM: Polypeptide-transport-associated domain protein, ShlB-type; KEGG: pau:PA14_61190 hemolysin activation/secretion protein YP_916244.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: filamentous haemagglutinin domain protein; GLUG domain protein; KEGG: pau:PA14_61200 hypothetical protein YP_916245.1 PFAM: Sel1 domain protein repeat-containing protein; peptidase C14, caspase catalytic subunit p20; SMART: peptidase C14, caspase precursor p45; KEGG: mlo:mlr2366 hypothetical protein YP_916247.1 KEGG: bms:BRA0423 outer membrane protein, 31 kDa YP_916248.1 PFAM: Hemolysin-type calcium-binding region; KEGG: sil:SPO1617 type I secretion target repeat protein YP_916250.1 PFAM: LytTr DNA-binding region; KEGG: sil:SPO1616 transcriptional regulator YP_916251.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: rsp:RSP_0463 cation efflux transporter, CDF family YP_916252.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc02869 ATP-binding ABC transporter protein YP_916253.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_2708 binding-protein-dependent transport systems inner membrane component YP_916254.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_1355 binding-protein-dependent transport systems inner membrane component YP_916255.1 PFAM: extracellular solute-binding protein, family 1; KEGG: mes:Meso_2706 extracellular solute-binding protein, family 1 YP_916256.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_916257.1 PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: mes:Meso_2705 ATPase, BadF/BadG/BcrA/BcrD type YP_916258.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: mlo:mll4768 transcriptional regulator, (GntR family) YP_916259.1 PFAM: sugar isomerase (SIS); KEGG: mlo:mll4767 glucosamine-fructose-6-phosphate aminotransferase YP_916260.1 KEGG: rsp:RSP_1296 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_916261.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp; KEGG: sil:SPOA0323 cyclic nucleotide-binding protein YP_916263.1 PFAM: cytochrome c oxidase, subunit III; KEGG: sil:SPOA0213 nitric oxide reductase E protein YP_916264.1 PFAM: von Willebrand factor, type A; KEGG: sil:SPOA0214 nitric oxide reductase D protein YP_916265.1 PFAM: ATPase associated with various cellular activities, AAA_5; CbbQ/NirQ/NorQ C-terminal domain protein; KEGG: sil:SPOA0215 nitric oxide reductase Q protein YP_916266.1 PFAM: cytochrome c oxidase, subunit I; KEGG: sil:SPOA0216 nitric oxide reductase, large subunit YP_916267.1 KEGG: sil:SPOA0217 nitric oxide reductase, small subunit YP_916268.1 PFAM: ApbE family lipoprotein; KEGG: rde:RD1_1552 nitrous-oxide reductase protein NosX YP_916269.1 PFAM: FMN-binding domain protein; KEGG: rde:RD1_1564 nitrous oxide reductase regulatory protein NosR YP_916270.1 PFAM: cytochrome c, class I; cytochrome d1, heme region; KEGG: sil:SPOA0220 cytochrome cd1 nitrite reductase YP_916271.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rde:RD1_1566 uroporphyrin-III C-methyltransferase YP_916272.1 KEGG: rde:RD1_1567 cytochrome c (c55X) YP_916273.1 PFAM: cytochrome d1, heme region; KEGG: sil:SPOA0223 cytochrome cd1 nitrite reductase YP_916274.1 KEGG: sil:SPOA0224 nitrite reductase heme biosynthesis D/L protein YP_916275.1 KEGG: rde:RD1_1570 nitrite reductase heme biosynthesis G YP_916276.1 KEGG: sil:SPOA0226 nitrite reductase heme biosynthesis H protein YP_916277.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sil:SPOA0227 nitrite reductase heme biosynthesis J protein YP_916278.1 PFAM: cytochrome d1, heme region; KEGG: sil:SPOA0228 nitrite reductase protein N YP_916279.1 KEGG: rde:RD1_1575 hypothetical protein YP_916280.1 KEGG: atc:AGR_L_481 catalase; TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_916281.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_916282.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_916283.1 KEGG: rsp:RSP_0562 hypothetical protein YP_916284.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_916285.1 PFAM: protein of unknown function DUF81; KEGG: sit:TM1040_3018 protein of unknown function DUF81 YP_916286.1 PFAM: L-asparaginase II; KEGG: rsp:RSP_1384 hypothetical protein YP_916287.1 KEGG: rsp:RSP_1383 hypothetical protein YP_916288.1 TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein; KEGG: rsp:RSP_1382 radical SAM superfamily protein YP_916289.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_916290.1 PFAM: peptidase M23B; KEGG: rsp:RSP_0933 hypothetical protein YP_916291.1 KEGG: sil:SPO3812 carboxyl-terminal protease family protein; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_916292.1 hydrolyzes diadenosine polyphosphate YP_916293.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: rsp:RSP_1125 membrane bound lytic murein transglycosylase B YP_916294.1 KEGG: sil:SPO3336 hypothetical protein YP_916295.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: jan:Jann_2447 YbaK/prolyl-tRNA synthetase associated protein YP_916296.1 PFAM: Transglycosylase-associated protein; KEGG: jan:Jann_0350 transglycosylase-associated protein YP_916297.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_916298.1 PFAM: conserved hypothetical protein 730; KEGG: rsp:RSP_1132 hypothetical protein YP_916300.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_916301.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: rsp:RSP_0865 hypothetical protein YP_916303.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_916305.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_916306.1 KEGG: sil:SPO0213 hypothetical protein YP_916307.1 KEGG: sil:SPO2875 hypothetical protein YP_916308.1 TIGRFAM: cobalt transporter, subunit CbtA; KEGG: sit:TM1040_2222 cobalt transporter subunit CbtA YP_916309.1 KEGG: sit:TM1040_2223 conserved hypothetical protein YP_916310.1 KEGG: rde:RD1_3815 cobalamin biosynthesis protein BluB; TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase YP_916311.1 KEGG: bbr:BB2359 hypothetical protein YP_916312.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_916313.1 PFAM: protein of unknown function DUF1636; KEGG: rsp:RSP_2829 hypothetical protein YP_916314.1 TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: sit:TM1040_2209 cobalamin (vitamin B12) biosynthesis CobW YP_916315.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_916316.1 TIGRFAM: precorrin-3B synthase; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; KEGG: sit:TM1040_2211 precorrin-3B synthase YP_916317.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_916318.1 TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rsp:RSP_2826 precorrin-2 C20-methyltransferase YP_916319.1 TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rsp:RSP_2824 precorrin-3B C17-methyltransferase YP_916320.1 PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: rsp:RSP_2825 precorrin-6x reductase YP_916321.1 KEGG: rsp:RSP_2823 precorrin-6y C5,15-methyltransferase; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_916322.1 KEGG: bja:blr3270 precorrin methylase YP_916323.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rsp:RSP_2821 precorrin-4 C11-methyltransferase YP_916324.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_916325.1 catalyzes the formation of precorrin 6x from precorrin 5 YP_916326.1 KEGG: sil:SPO2878 hypothetical protein YP_916327.1 PFAM: cytochrome c, class II; KEGG: rsp:RSP_0474 cytochrome c' YP_916328.1 PFAM: cytochrome B561; KEGG: rsp:RSP_0475 cytochrome b YP_916329.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_916330.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: rsp:RSP_1694 probable short-chain dehydrogenase/reductase YP_916331.1 KEGG: rsp:RSP_6016 hypothetical protein YP_916332.1 TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: jan:Jann_0549 cobalamin adenosyltransferase YP_916333.1 PFAM: electron transfer flavoprotein beta-subunit; KEGG: sit:TM1040_2427 electron transfer flavoprotein beta-subunit YP_916334.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: sit:TM1040_2426 electron transfer flavoprotein, alpha subunit YP_916335.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_916336.1 PFAM: protein of unknown function DUF205; KEGG: rsp:RSP_1004 hypothetical protein YP_916337.1 TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: rsp:RSP_1003 dihydroorotase and related cyclic amidohydrolase YP_916338.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_916339.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_916340.1 KEGG: sil:SPO1135 hypothetical protein YP_916341.1 PFAM: SirA family protein; KEGG: sil:SPO1895 SirA family protein YP_916342.1 PFAM: Auxin Efflux Carrier; KEGG: rsp:RSP_0851 transporter, AEC family YP_916343.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_916344.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: atc:AGR_C_3767 hypothetical protein YP_916345.1 KEGG: sit:TM1040_3453 conserved hypothetical protein YP_916346.1 PFAM: cytochrome B561; KEGG: rde:RD1_3654 cytochrome b561 YP_916347.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_916348.1 PFAM: esterase; KEGG: ppu:PP_0532 hypothetical protein YP_916349.1 KEGG: tac:Ta1322 surface antigen genes (Methanosarcina mazei) related protein YP_916350.1 PFAM: periplasmic binding protein; KEGG: rpb:RPB_2696 periplasmic binding protein YP_916351.1 PFAM: transport system permease protein; KEGG: pfl:PFL_3501 heme/hemin ABC transporter, permease protein YP_916352.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rpb:RPB_2698 ABC transporter related YP_916353.1 PFAM: protein of unknown function DUF1178; KEGG: rsp:RSP_2387 hypothetical protein YP_916354.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: rsp:RSP_2394 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase) YP_916355.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: rsp:RSP_2864 pentose-5-phosphate-3-epimerase YP_916356.1 PFAM: Hsp33 protein; KEGG: sil:SPO0024 chaperonin, 33 kDa YP_916357.1 PFAM: NUDIX hydrolase; KEGG: rde:RD1_0410 hydrolase YP_916358.1 PFAM: Polynucleotide adenylyltransferase region; KEGG: rsp:RSP_1205 poly A polymerase family protein YP_916359.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_1203 ABC multidrug efflux pump, fused ATPase and inner membrane subunits YP_916360.1 PFAM: (Uracil-5)-methyltransferase; KEGG: sil:SPO0029 23S rRNA (uracil-5-)-methyltransferase RumA YP_916361.1 KEGG: rsp:RSP_1201 hypothetical protein YP_916362.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: bja:blr5350 glutathione S-transferase YP_916363.1 PFAM: Allergen V5/Tpx-1 family protein; KEGG: rsp:RSP_1200 hypothetical protein YP_916364.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sil:SPO0075 ErfK/YbiS/YcfS/YnhG family protein/Tat domain protein YP_916366.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_916367.1 KEGG: rsp:RSP_1196 SAM-dependent methyltransferase YP_916368.1 KEGG: rsp:RSP_1195 competence protein F YP_916369.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; glutaredoxin 2; KEGG: rsp:RSP_1194 glutaredoxin YP_916370.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sil:SPO0069 hydrolase, carbon-nitrogen family YP_916371.1 PFAM: regulatory protein, MarR; KEGG: rsp:RSP_1191 transcriptional regulator, MarR family YP_916372.1 Involved in ubiquinone biosynthesis YP_916373.1 KEGG: rsp:RSP_1174 prolyl aminopeptidase; TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold YP_916374.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_916375.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_916376.1 PFAM: protein of unknown function DUF448; KEGG: jan:Jann_0039 protein of unknown function DUF448 YP_916377.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_916379.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: sil:SPO0060 mutator MutT protein YP_916380.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_916381.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: jan:Jann_0290 PpiC-type peptidyl-prolyl cis-trans isomerase YP_916382.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_916383.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rsp:RSP_1138 two component transcriptional regulator, winged helix family YP_916384.1 PFAM: regulatory protein, MarR; KEGG: rsp:RSP_1139 transcriptional regulator, MarR family YP_916385.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_916386.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: rsp:RSP_1158 PTS IIA-like nitrogen-regulatory protein PtsN YP_916387.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: rsp:RSP_1157 ribosomal subunit interface protein Y YP_916388.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_1156 ABC transporter, ATPase subunit YP_916389.1 PFAM: OstA family protein; KEGG: sil:SPO0080 hypothetical protein YP_916390.1 KEGG: rsp:RSP_1154 hypothetical protein YP_916391.1 KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_916392.1 PFAM: 3'-5' exonuclease; KEGG: rsp:RSP_1152 ribonuclease D YP_916393.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: bmb:BruAb2_1126 TonB dependent receptor domain protein YP_916394.1 KEGG: mes:Meso_2258 transcriptional regulator, XRE family YP_916395.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: mes:Meso_2257 sulphate transporter YP_916396.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_916397.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_916398.1 PFAM: Patatin; KEGG: sus:Acid_5056 patatin YP_916399.1 KEGG: atc:AGR_L_695 hypothetical protein YP_916400.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: rsp:RSP_2661 iron-containing alcohol dehydrogenase YP_916401.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; KEGG: rsp:RSP_2662 glycerol kinase YP_916402.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: rsp:RSP_0457 probable glycerol-3-phosphate regulon repressor YP_916403.1 TIGRFAM: kynureninase; PFAM: aminotransferase, class V; KEGG: mlo:mll0621 probable kynureninase (kyurenine hydrolase) YP_916404.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20324 ThuR, regulatory protein for trehalosemaltose transport system YP_916405.1 KEGG: rsp:RSP_6001 hypothetical protein YP_916407.1 PFAM: regulatory protein, TetR; KEGG: rsp:RSP_6137 transcriptional regulator, TetR family YP_916409.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_916410.1 KEGG: sil:SPO0171 flagellar biosynthetic protein FliR YP_916411.1 membrane protein involved in the flagellar export apparatus YP_916413.1 KEGG: rsp:RSP_1316 flagellar motor protein YP_916414.1 KEGG: rpa:RPA1896 homologue of rhodobacter capsulatus gene transfer agent (GTA) orfg6 (21% identity) YP_916416.1 PFAM: phage Terminase; KEGG: rsp:RSP_0213 phage terminase-like protein large subunit YP_916417.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: rsp:RSP_0212 HNH nuclease YP_916418.1 KEGG: rsp:RSP_0211 hypothetical protein YP_916419.1 TIGRFAM: phage prohead protease, HK97 family; PFAM: peptidase U35, phage prohead HK97; KEGG: rsp:RSP_0209 possible prophage Lp3 protein 18 YP_916420.1 KEGG: rsp:RSP_0208 hypothetical protein YP_916421.1 KEGG: rsp:RSP_0207 hypothetical protein YP_916422.1 KEGG: rsp:RSP_0206 hypothetical protein YP_916427.1 PFAM: phage integrase family protein; KEGG: rsp:RSP_2080 tyrosine recombinase YP_916428.1 KEGG: sit:TM1040_2951 chemotaxis protein MotA YP_916429.1 KEGG: rsp:RSP_1315 hypothetical protein YP_916430.1 KEGG: sit:TM1040_2949 conserved hypothetical protein YP_916431.1 PFAM: flagellar basal body-associated protein FliL; KEGG: rsp:RSP_1313 possible flagellar synthesis protein YP_916432.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_916434.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: rsp:RSP_1310 flagellar motor switch protein FliN/FliY YP_916435.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_916436.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: mlo:mll5520 RND efflux membrane fusion protein YP_916437.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ret:RHE_PF00285 probable protein secretion protein, HlyD family YP_916438.1 PFAM: acriflavin resistance protein; KEGG: ret:RHE_PF00284 probable efflux transporter protein, acriflavin resistance protein family YP_916439.1 KEGG: rsp:RSP_1359 DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_916440.1 KEGG: sit:TM1040_2661 conserved hypothetical protein YP_916441.1 PFAM: major facilitator superfamily MFS_1; KEGG: rsp:RSP_1362 major facilitator superfamily (MFS) transporter YP_916442.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_916443.1 KEGG: rsp:RSP_1364 hypothetical protein YP_916444.1 PFAM: beta-lactamase; KEGG: bte:BTH_II1108 beta-lactamase YP_916445.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: rde:RD1_0365 hypothetical protein YP_916446.1 catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA YP_916447.1 PFAM: regulatory protein, LysR; KEGG: nha:Nham_2952 transcriptional regulator, ModE family YP_916448.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: atc:AGR_C_4642 molybdate-binding periplasmic protein YP_916449.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rde:RD1_2914 molybdate ABC transporter, permease protein YP_916450.1 KEGG: sil:SPO0697 molybdate ABC transporter, ATP-binding protein; TIGRFAM: molybdate ABC transporter, ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase YP_916451.1 KEGG: rsp:RSP_1496 hypothetical protein YP_916452.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: rsp:RSP_1497 outer membrane lipoprotein carrier protein YP_916453.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; KEGG: rsp:RSP_1492 UbiH/COQ6 monooxygenase family YP_916454.1 PFAM: Amidase; KEGG: rsp:RSP_1493 amidase YP_916455.1 PFAM: aminotransferase, class I and II; KEGG: rsp:RSP_1494 aspartate aminotransferase YP_916456.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: sil:SPO3416 FtsK/SpoIIIE family protein YP_916457.1 KEGG: ppu:PP_0532 hypothetical protein YP_916458.1 PFAM: secretion protein HlyD family protein; KEGG: rru:Rru_A3484 secretion protein HlyD YP_916459.1 KEGG: sme:SMc00563 transport protein transmembrane YP_916460.1 PFAM: regulatory protein, MarR; KEGG: sme:SMc00562 transcription regulator protein YP_916461.1 PFAM: protein of unknown function DUF490; KEGG: rsp:RSP_1183 hypothetical protein YP_916462.1 PFAM: surface antigen (D15); KEGG: rsp:RSP_1182 outer membrane protein YP_916463.1 PFAM: Glucokinase; KEGG: sil:SPO0864 glucokinase YP_916465.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_916466.1 PFAM: histidine triad (HIT) protein; KEGG: bbr:BB0059 histidine triad protein YP_916467.1 KEGG: sit:TM1040_2834 conserved hypothetical protein YP_916468.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rsp:RSP_0913 enoyl-CoA hydratase/isomerase YP_916469.1 KEGG: sil:SPO3441 hypothetical protein YP_916470.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: jan:Jann_0403 peptidase U62, modulator of DNA gyrase YP_916471.1 PFAM: inositol monophosphatase; KEGG: rsp:RSP_0917 inositol monophosphatase YP_916472.1 PFAM: flavin reductase domain protein, FMN-binding; KEGG: atc:AGR_L_3083 hypothetical protein YP_916473.1 KEGG: ppu:PP_4887 hypothetical protein YP_916474.1 PFAM: protein of unknown function DUF330; KEGG: sit:TM1040_3329 protein of unknown function DUF330 YP_916475.1 PFAM: Mammalian cell entry related domain protein; KEGG: sit:TM1040_3328 mammalian cell entry related YP_916476.1 PFAM: Paraquat-inducible protein A; KEGG: sit:TM1040_3327 paraquat-inducible protein A YP_916477.1 PFAM: Paraquat-inducible protein A; KEGG: sit:TM1040_3326 paraquat-inducible protein A YP_916478.1 KEGG: rsp:RSP_1302 chemotaxis MotB protein YP_916479.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: rsp:RSP_1303 flagellar hook protein YP_916480.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_916481.1 KEGG: rsp:RSP_1305 flagellar hook-associated protein YP_916482.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_916483.1 PFAM: transposase, IS4 family protein; KEGG: nmu:Nmul_A2650 transposase, IS4 YP_916484.1 KEGG: mag:amb0408 transposase and inactivated derivative YP_916485.1 PFAM: carbonic anhydrase; KEGG: rsp:RSP_1377 carbonic anhydrase YP_916486.1 KEGG: rde:RD1_0313 hypothetical protein YP_916487.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: sit:TM1040_3455 leucyl aminopeptidase YP_916488.1 PFAM: NLP/P60 protein; KEGG: rsp:RSP_1380 hypothetical protein YP_916489.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: sil:SPO3307 saccharopine dehydrogenase YP_916490.1 PFAM: glucose sorbosone dehydrogenase; KEGG: neu:NE1997 glucose dehydrogenase B YP_916491.1 KEGG: sil:SPO3310 hypothetical protein YP_916492.1 KEGG: rsp:RSP_3367 hypothetical protein YP_916493.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_916494.1 PFAM: peptidase M16 domain protein; KEGG: rde:RD1_0659 peptidase, M16 family YP_916495.1 PFAM: peptidase M16 domain protein; KEGG: rsp:RSP_1097 zinc protease YP_916496.1 KEGG: rsp:RSP_1098 hypothetical protein YP_916497.1 TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8, signal peptidase II; KEGG: rsp:RSP_1099 signal peptidase II YP_916498.1 involved in de novo purine biosynthesis YP_916499.1 PFAM: Heparinase II/III family protein; KEGG: sil:SPO3375 hypothetical protein YP_916500.1 PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; methyltransferase small; KEGG: sil:SPO3376 ribosomal RNA small subunit methyltransferase B YP_916501.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: atc:AGR_C_4619 hypothetical protein YP_916502.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: ret:RHE_CH03412 probable multidrug efflux transporter protein YP_916503.1 catalyzes the formation of selenophosphate from selenide and ATP YP_916504.1 KEGG: sme:SMa0026 hypothetical protein YP_916505.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: rpe:RPE_2404 uncharacterized domain 1 YP_916506.1 PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; Methyltransferase type 11; KEGG: sit:TM1040_1992 protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_916507.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: rsp:RSP_0251 outer membrane efflux protein YP_916508.1 KEGG: rsp:RSP_0250 hypothetical protein YP_916509.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: rsp:RSP_2543 peptidoglycan-binding LysM (possible peptidase) YP_916510.1 KEGG: rsp:RSP_2544 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_916511.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_916512.1 PFAM: protein of unknown function DUF81; KEGG: rsp:RSP_2206 hypothetical protein YP_916513.1 KEGG: rde:RD1_1641 hypothetical protein YP_916514.1 PFAM: protein of unknown function DUF482; KEGG: sil:SPO3732 hypothetical protein YP_916515.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: jan:Jann_0436 glycerophosphoryl diester phosphodiesterase YP_916516.1 PFAM: Endoribonuclease L-PSP; KEGG: rsp:RSP_0894 hypothetical protein YP_916517.1 KEGG: sal:Sala_1312 hypothetical protein YP_916518.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain protein; KEGG: rsp:RSP_0876 chromosome segregation protein SMC2 YP_916519.1 PFAM: LrgA family protein; KEGG: bcn:Bcen_5769 LrgA YP_916520.1 PFAM: LrgB family protein; KEGG: rsp:RSP_3332 transmembrane protein YP_916522.1 KEGG: rsp:RSP_6107 hypothetical protein YP_916523.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_916524.1 KEGG: jan:Jann_1003 hypothetical protein YP_916525.1 KEGG: mes:Meso_0838 sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_916526.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mes:Meso_0839 ABC transporter related YP_916527.1 PFAM: inner-membrane translocator; KEGG: mes:Meso_0840 inner-membrane translocator YP_916528.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: rsp:RSP_1371 2-dehydro-3-deoxygalactonokinase YP_916529.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_916530.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: jan:Jann_3831 senescence marker protein-30 (SMP-30) YP_916531.1 PFAM: Aldose 1-epimerase; KEGG: sme:SMc03798 probable aldose 1-epimerase protein YP_916532.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sil:SPO1722 transcriptional regulator, GntR family YP_916533.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: bcn:Bcen_5340 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_916534.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: sil:SPO2409 oxidoreductase, short chain dehydrogenase/reductase family YP_916535.1 PFAM: aldehyde dehydrogenase; KEGG: rsp:RSP_1507 aldehyde dehydrogenase YP_916536.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sil:SPO3383 thiol-specific antioxidant protein YP_916537.1 PFAM: glycosyl transferase, family 25; KEGG: sfr:Sfri_3927 glycosyl transferase, family 25 YP_916539.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein; KEGG: rsp:RSP_1112 polyribonucleotide nucleotidyltransferase YP_916540.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_916541.1 KEGG: sil:SPO2352 type I secretion target repeat protein YP_916542.1 PFAM: alanine racemase domain protein; KEGG: rsp:RSP_0844 hypothetical protein YP_916543.1 KEGG: sil:SPO3430 outer membrane porin YP_916544.1 KEGG: sil:SPO3431 hypothetical protein YP_916545.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_916546.1 KEGG: rsp:RSP_0839 predicted secreted periplasmic protein YP_916547.1 TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; KEGG: sil:SPO3434 DNA polymerase III delta subunit YP_916548.1 PFAM: HI0933 family protein; KEGG: rsp:RSP_0836 flavoprotein YP_916549.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: rde:RD1_0053 glutathione S-transferase family protein YP_916550.1 PFAM: major facilitator superfamily MFS_1; KEGG: rsp:RSP_1372 major facilitator superfamily (MFS) transporter YP_916551.1 TIGRFAM: 5'-nucleotidase, lipoprotein e(P4) family; PFAM: acid phosphatase (Class B); KEGG: hpy:HP1285 conserved hypothetical secreted protein YP_916552.1 PFAM: major facilitator superfamily MFS_1; KEGG: rsp:RSP_1373 major facilitator superfamily (MFS) transporter YP_916553.1 PFAM: glycosyl transferase, group 1; KEGG: rsp:RSP_1374 lipopolysaccharide core biosynthesis mannosyltransferase protein YP_916554.1 KEGG: rsp:RSP_1375 hypothetical protein YP_916555.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_916556.1 KEGG: sit:TM1040_3460 conserved hypothetical protein YP_916557.1 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_916558.1 SMART: PAS domain containing protein; KEGG: rsp:RSP_1521 hypothetical protein YP_916559.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_1520 sensor histidine kinase PrrB (RegB) YP_916560.1 PFAM: electron transport protein SCO1/SenC; KEGG: rde:RD1_0460 SenC protein YP_916561.1 PFAM: response regulator receiver; KEGG: sit:TM1040_2838 response regulator receiver protein YP_916562.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: rsp:RSP_1517 histone-like protein of HNS family YP_916563.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: rsp:RSP_1516 S-adenosyl L-homocystein hydrolase YP_916564.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_916565.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: ppr:PBPRA3390 FxsA protein YP_916566.1 PFAM: import inner membrane translocase, subunit Tim44; KEGG: jan:Jann_0191 import inner membrane translocase, subunit Tim44 YP_916567.1 PFAM: Smr protein/MutS2; KEGG: rsp:RSP_1241 Smr protein/MutS2 YP_916568.1 PFAM: protein of unknown function DUF900, hydrolase family protein; KEGG: sil:SPO3883 lipoprotein YP_916569.1 KEGG: rpb:RPB_1461 hypothetical protein YP_916570.1 heat shock protein involved in degradation of misfolded proteins YP_916571.1 heat shock protein involved in degradation of misfolded proteins YP_916572.1 KEGG: rsp:RSP_1530 hypothetical protein YP_916573.1 TIGRFAM: thioredoxin; PFAM: glutaredoxin; Thioredoxin domain; KEGG: jan:Jann_4067 thioredoxin YP_916574.1 TIGRFAM: UvrD-like DNA helicase, C terminal; PFAM: UvrD/REP helicase; KEGG: rsp:RSP_1527 helicase, UvrD/Rep family YP_916575.1 KEGG: rsp:RSP_1525 helicase/exonuclease YP_916576.1 PFAM: Nucleotidyl transferase; KEGG: rsp:RSP_1524 nucleotidyltransferase family protein YP_916577.1 PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; KEGG: rpb:RPB_0625 hypothetical protein YP_916578.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_916579.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_916580.1 KEGG: rsp:RSP_1107 hypothetical protein YP_916581.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_916582.1 KEGG: sme:SMc02687 hypothetical protein YP_916583.1 PFAM: beta-lactamase domain protein; KEGG: rsp:RSP_0799 hypothetical protein YP_916584.1 PFAM: pseudouridine synthase; KEGG: rsp:RSP_1506 pseudouridine synthase, Rlu YP_916585.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: rru:Rru_A3172 lysine exporter protein (LysE/YggA) YP_916586.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: sit:TM1040_0070 glutathione-dependent formaldehyde-activating, GFA YP_916587.1 KEGG: rde:RD1_0024 hypothetical protein YP_916589.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: rsp:RSP_2567 sulfolipid biosynthesis protein YP_916590.1 PFAM: glycosyl transferase, family 8; KEGG: rsp:RSP_2568 glycosyl transferase (sulfolipid biosynthesis) protein YP_916591.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: rsp:RSP_2569 sulfolipid (UDP-sulfoquinovose) biosynthesis protein YP_916592.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: rru:Rru_A3399 transcriptional regulator, BadM/Rrf2 family YP_916593.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_916594.1 KEGG: rsp:RSP_1235 dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase YP_916595.1 KEGG: rde:RD1_0440 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_916596.1 TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN; KEGG: rde:RD1_0088 ribonuclease BN YP_916597.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: pae:PA2722 hypothetical protein YP_916598.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: pen:PSEEN2025 transporter, LysE family YP_916599.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation/phosphoacceptor; KEGG: rsp:RSP_1271 periplasmic sensor signal transduction histidine kinase YP_916600.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_916601.1 KEGG: rsp:RSP_1273 hypothetical protein YP_916602.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media YP_916603.1 PFAM: 2-nitropropane dioxygenase, NPD; KEGG: jan:Jann_2812 2-nitropropane dioxygenase, NPD YP_916604.1 PFAM: aldo/keto reductase; KEGG: sil:SPO1433 oxidoreductase, aldo/keto reductase family YP_916605.1 TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: sme:SMa0015 SelB selenocysteine-specific elongation factor YP_916606.1 TIGRFAM: formate dehydrogenase accessory protein FdhE; PFAM: formate dehydrogenase accessory protein; KEGG: sme:SMa0009 probable FdhE formate formation YP_916607.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: sme:SMa0007 probable FdoI formate dehydrogenase-O,gamma subunit YP_916608.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sme:SMa0005 probable FdoH formate dehydrogenase-O, beta subunit YP_916609.1 KEGG: sme:SMa0002 probable FdoG formate dehydrogenase-O alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_916610.1 PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sme:SMa0002 probable FdoG formate dehydrogenase-O alpha subunit YP_916611.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: rsp:RSP_3979 ferredoxin YP_916612.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: sit:TM1040_3219 Rieske (2Fe-2S) region YP_916613.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_916614.1 binds the polymerase to DNA and acts as a sliding clamp YP_916615.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_916616.1 KEGG: sit:TM1040_2799 adenine deaminase; TIGRFAM: adenine deaminase; PFAM: amidohydrolase YP_916617.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_916618.1 PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: sil:SPO3197 hypothetical protein YP_916619.1 PFAM: protein of unknown function DUF306, Meta and HslJ YP_916620.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: rsp:RSP_1679 acyl-CoA dehydrogenase YP_916621.1 PFAM: protein of unknown function DUF81; KEGG: sit:TM1040_2445 protein of unknown function DUF81 YP_916622.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_916623.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_1127 acetyltransferase, GNAT family YP_916624.1 KEGG: rsp:RSP_1006 hypothetical protein YP_916625.1 TIGRFAM: glutamate--cysteine ligase; PFAM: glutamate--cysteine ligase, GCS2; KEGG: sil:SPO3626 glutamate--cysteine ligase YP_916626.1 KEGG: jan:Jann_1905 hypothetical protein YP_916627.1 PFAM: regulatory protein, TetR; KEGG: rsp:RSP_0014 transcriptional regulator, TetR family YP_916628.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: rsp:RSP_1686 phosphocarrier HPr protein YP_916629.1 PFAM: PTS system fructose subfamily IIA component; KEGG: sil:SPO0714 PTS system IIA component, Man family YP_916630.1 PFAM: Uncharacterized P-loop ATPase UPF0042; KEGG: rsp:RSP_1684 hypothetical protein YP_916631.1 KEGG: sil:SPO0712 HPr serine kinase/phosphatase domain protein YP_916632.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_916633.1 KEGG: rsp:RSP_1126 exoribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein YP_916634.1 KEGG: sme:SMc03086 NAD-dependent formate dehydrogenase delta subunit protein YP_916635.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase, subunit FdhD; KEGG: rpd:RPD_0622 formate dehydrogenase family accessory protein FdhD YP_916636.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: rsp:RSP_1080 NAD-dependent formate dehydrogenase, alpha subunit YP_916637.1 PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rsp:RSP_1079 NAD dependent formate dehydrogenase, beta subunit (51 kDa) YP_916638.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; KEGG: gbe:GbCGDNIH1_1932 NAD-dependent formate dehydrogenase gamma subunit (FdsG) YP_916639.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rsp:RSP_1077 transcriptional regulator, LysR family YP_916640.1 TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS; KEGG: rsp:RSP_2127 component of phosphoribosylformylglycinamidine (FGAM) synthetase YP_916641.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_916642.1 PFAM: protein of unknown function DUF1476; KEGG: sil:SPO1886 hypothetical protein YP_916643.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: rsp:RSP_2204 multidrug efflux pump, MATE family YP_916644.1 PFAM: thioesterase superfamily protein; KEGG: rsp:RSP_2203 hypothetical protein YP_916645.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: sil:SPO2911 thioesterase family protein YP_916646.1 PFAM: regulatory protein, MerR; KEGG: rsp:RSP_2201 transcriptional regulator, MerR family YP_916647.1 PFAM: regulatory protein, MerR; KEGG: sit:TM1040_1556 transcriptional regulator, MerR family YP_916648.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: rsp:RSP_2199 acyl-CoA dehydrogenase YP_916649.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: sit:TM1040_1560 glutathione S-transferase-like YP_916650.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_916651.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: rsp:RSP_2196 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase YP_916652.1 PFAM: PfkB domain protein; KEGG: jan:Jann_1671 PfkB YP_916653.1 KEGG: rsp:RSP_1031 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_916654.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: sit:TM1040_2450 transcriptional regulator, AraC family YP_916655.1 PFAM: OmpA/MotB domain protein; KEGG: rde:RD1_0967 OmpA family domain protein YP_916656.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel. YP_916657.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B' is part of the membrane proton channel. YP_916658.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_916659.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_916660.1 KEGG: sit:TM1040_2595 ATP synthase F0, subunit I YP_916661.1 PFAM: regulatory protein, ArsR; KEGG: sil:SPO3238 transcriptional regulator, ArsR family YP_916662.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sit:TM1040_1548 5'-nucleotidase-like YP_916663.1 PFAM: protein of unknown function DUF952; KEGG: rsp:RSP_0956 hypothetical protein YP_916664.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_916665.1 KEGG: rsp:RSP_2481 serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein YP_916666.1 KEGG: jan:Jann_1647 hypothetical protein YP_916667.1 KEGG: rsp:RSP_2479 phage host specificity protein YP_916668.1 TIGRFAM: phage cell wall peptidase, NlpC/P60 family; PFAM: NLP/P60 protein; KEGG: rde:RD1_3017 hypothetical protein YP_916669.1 KEGG: sit:TM1040_1070 phage conserved hypothetical protein BR0599 YP_916670.1 KEGG: sit:TM1040_1069 conserved hypothetical protein YP_916671.1 KEGG: jan:Jann_1642 phage-related minor tail protein-like YP_916672.1 KEGG: sit:TM1040_1067 conserved hypothetical protein YP_916673.1 KEGG: sil:SPO2256 hypothetical protein YP_916674.1 TIGRFAM: phage major tail protein, TP901-1 family; KEGG: sit:TM1040_1065 phage major tail protein, TP901-1 YP_916675.1 KEGG: jan:Jann_1638 hypothetical protein YP_916676.1 KEGG: sil:SPO2259 head-tail adaptor YP_916677.1 KEGG: rsp:RSP_2472 hypothetical protein YP_916678.1 TIGRFAM: phage major capsid protein, HK97 family; PFAM: phage major capsid protein, HK97; KEGG: sil:SPO2261 major capsid protein, HK97 family YP_916679.1 TIGRFAM: phage prohead protease, HK97 family; PFAM: peptidase U35, phage prohead HK97; KEGG: rsp:RSP_2470 prohead protease YP_916680.1 KEGG: rde:RD1_3031 hypothetical protein YP_916681.1 TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein; KEGG: rde:RD1_3033 phage portal protein YP_916682.1 PFAM: protein of unknown function DUF264; KEGG: rde:RD1_3034 hypothetical protein YP_916683.1 PFAM: aminodeoxychorismate lyase; KEGG: rsp:RSP_2465 hypothetical protein YP_916684.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_916685.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mmc:Mmcs_4156 enoyl-CoA hydratase/isomerase YP_916686.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: bms:BRA0447 acyl-CoA dehydrogenase YP_916687.1 KEGG: bms:BRA0448 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase YP_916688.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: bms:BRA0449 3-hydroxyacyl-CoA dehydrogenase YP_916689.1 PFAM: AMP-dependent synthetase and ligase; KEGG: bms:BRA0450 acetyl-CoA synthetase YP_916690.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: bms:BRA0451 transcriptional regulator, AraC family YP_916691.1 KEGG: rsp:RSP_1308 hypothetical protein YP_916692.1 KEGG: sil:SPOA0303 replication protein YP_916693.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: sil:SPOA0304 replication protein YP_916694.1 KEGG: sil:SPOA0305 hypothetical protein YP_916695.1 KEGG: rsp:RSP_7166 hypothetical protein YP_916696.1 KEGG: atc:AGR_L_1708 biotin synthetase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_916697.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_916698.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_916699.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: ngo:NGO0308 adenosylmethionine-8-amino-7-oxononanoate aminotranferase YP_916700.1 PFAM: protein of unknown function DUF452; KEGG: nme:NMB0473 hypothetical protein YP_916701.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cte:CT0049 biotin synthesis protein YP_916702.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: mlo:mlr7428 transcription regulator YP_916703.1 PFAM: 2',5' RNA ligase; KEGG: bxe:Bxe_A1918 ligase YP_916704.1 PFAM: protein of unknown function DUF162; KEGG: rde:RD1_0071 hypothetical protein YP_916705.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: rde:RD1_0072 4Fe-4S binding domain protein YP_916706.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: rde:RD1_0073 hypothetical protein YP_916707.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: par:Psyc_1653 glycolate/L-lactate:H+ symporter YP_916708.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_916709.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein; KEGG: mag:amb0238 transcriptional regulator YP_916710.1 KEGG: rsp:RSP_2678 hypothetical protein YP_916711.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: eca:ECA4158 gluconate permease YP_916712.1 KEGG: tfu:Tfu_2114 carbohydrate kinase, thermoresistant glucokinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase YP_916713.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_916714.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sme:SMc02159 hypothetical protein YP_916715.1 PFAM: phosphatidate cytidylyltransferase; KEGG: xcv:XCV0555 phosphatidate cytidiltransferase YP_916716.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: reu:Reut_B4015 phospholipid/glycerol acyltransferase YP_916717.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: rpb:RPB_2235 hypothetical protein YP_916718.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rpc:RPC_1868 secretion protein HlyD YP_916720.1 PFAM: regulatory protein, TetR; KEGG: rru:Rru_A1116 transcriptional regulator, TetR family YP_916721.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: atc:AGR_L_3215 RND multidrug efflux membrane fusion protein MexC precursor YP_916722.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: atc:AGR_L_3217 RND multidrug efflux transporter MexD YP_916723.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: atc:AGR_C_4622 hypothetical protein YP_916724.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_916725.1 PFAM: Exopolysaccharide synthesis, ExoD; KEGG: mes:Meso_1827 exopolysaccharide synthesis, ExoD YP_916726.1 PFAM: PfkB domain protein; KEGG: rsp:RSP_2257 fructokinase YP_916727.1 KEGG: rsp:RSP_2260 hypothetical protein YP_916728.1 KEGG: rsp:RSP_2261 antifreeze protein, type I YP_916730.1 KEGG: rsp:RSP_2263 hypothetical protein YP_916731.1 PFAM: toxic anion resistance family protein; KEGG: sil:SPO2986 tellurite resistance protein YP_916733.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: mes:Meso_0590 transcriptional regulator, AraC family YP_916734.1 PFAM: protein of unknown function UPF0118; KEGG: jan:Jann_2214 protein of unknown function UPF0118 YP_916735.1 PFAM: Saccharopine dehydrogenase; KEGG: rsp:RSP_1475 saccharopine dehydrogenase family YP_916736.1 TIGRFAM: carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: sme:SMb21631 carboxynorspermidine decarboxylase YP_916737.1 PFAM: oxidoreductase domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mes:Meso_2709 oxidoreductase-like YP_916738.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: rsp:RSP_0443 Rrf2 family transcriptional regulator YP_916739.1 KEGG: jan:Jann_2367 hypothetical protein YP_916740.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sil:SPO2028 HD domain protein YP_916741.1 Converts isocitrate to alpha ketoglutarate YP_916742.1 TIGRFAM: phosphoribosylformylglycinamidine synthase I; PFAM: CobB/CobQ domain protein glutamine amidotransferase; KEGG: rsp:RSP_2128 phosphoribosylformylglycinamidine synthase I (FGAM) synthase YP_916743.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_2129 sensor histidine kinase YP_916744.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sit:TM1040_1461 two component, sigma54 specific, transcriptional regulator, fis family YP_916745.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: sil:SPO1893 ribonuclease, Rne/Rng family YP_916746.1 PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: rde:RD1_2269 cytochrome c-type biogenesis protein CcdA YP_916747.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rsp:RSP_3833 enoyl-CoA hydratase YP_916748.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: sit:TM1040_1390 phenylacetic acid degradation-related protein YP_916749.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_916750.1 forms a direct contact with the tRNA during translation YP_916752.1 KEGG: lbl:LBL_1989 transposase, ISLbp9 YP_916753.1 PFAM: helicase domain protein; KEGG: rpe:RPE_2164 helicase domain protein YP_916754.1 KEGG: pat:Patl_4096 DNA-cytosine methyltransferase YP_916755.1 PFAM: transposase, IS4 family protein; KEGG: sil:SPOA0134 ISSpo7, transposase YP_916756.1 PFAM: Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug; KEGG: rso:RSc2920 hydroxamate-type ferrisiderophore receptor signal peptide protein YP_916757.1 PFAM: FecR protein; KEGG: nwi:Nwi_2050 probable FecR, iron siderophore sensor protein YP_916758.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: bbr:BB4120 ECF-family sigma factor YP_916759.1 PFAM: periplasmic binding protein; KEGG: ppu:PP_2418 iron ABC transporter, periplasmic iron-binding protein YP_916760.1 PFAM: transport system permease; KEGG: bmb:BruAb2_0477 iron compound ABC transporter, permease YP_916761.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_3390 ABC Fe3+-siderophores transporter, ATPase subunit YP_916762.1 TIGRFAM: pseudoazurin; PFAM: blue (type 1) copper domain protein; KEGG: rru:Rru_A1139 blue (type 1) copper subtype YP_916763.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: mba:Mbar_A0646 UbiE/COQ5 methyltransferase YP_916764.1 KEGG: hne:HNE_1237 DNA-binding protein YP_916765.1 KEGG: rpa:RPA2395 carboxyphosphonoenolpyruvate phosphonomutase YP_916766.1 TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; KEGG: rpe:RPE_3175 anaerobic ribonucleoside-triphosphate reductase activating protein YP_916767.1 KEGG: rpc:RPC_3516 hypothetical protein YP_916768.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_916769.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: rpe:RPE_3142 two component transcriptional regulator, LuxR family YP_916770.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: rpe:RPE_3141 signal transduction histidine kinase YP_916772.1 PFAM: Pyrrolo-quinoline quinone; KEGG: rpe:RPE_3139 pyrrolo-quinoline quinone YP_916773.1 SMART: extracellular solute-binding protein, family 3; KEGG: rpc:RPC_1908 extracellular solute-binding protein, family 3 YP_916774.1 PFAM: cytochrome c, class I; KEGG: rpc:RPC_1909 cytochrome c, class I YP_916775.1 PFAM: methanol dehydrogenase, beta subunit; KEGG: rpe:RPE_3136 methanol dehydrogenase, beta subunit YP_916776.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: rpe:RPE_3135 ATPase associated with various cellular activities, AAA_3 YP_916777.1 KEGG: rpc:RPC_1912 hypothetical protein YP_916778.1 KEGG: rpc:RPC_1913 MxaA protein YP_916779.1 PFAM: von Willebrand factor, type A; KEGG: rpe:RPE_3132 von Willebrand factor, type A YP_916780.1 KEGG: rpe:RPE_3131 hypothetical protein YP_916781.1 KEGG: rpe:RPE_3130 von Willebrand factor, type A YP_916782.1 KEGG: rpe:RPE_3129 MxaD protein YP_916783.1 PFAM: peptidase S15; dienelactone hydrolase; KEGG: tte:TTE1809 hydrolases of the alpha/beta superfamily YP_916786.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rru:Rru_A2312 TonB-dependent receptor YP_916787.1 PFAM: AMP-dependent synthetase and ligase; KEGG: bur:Bcep18194_B0670 AMP-dependent synthetase and ligase YP_916788.1 TIGRFAM: chorismate mutase related enzymes; PFAM: Chorismate mutase; KEGG: pfl:PFL_3489 isochorismate pyruvate-lyase YP_916789.1 PFAM: periplasmic binding protein; KEGG: ecs:ECs3913 ferrichrome-binding protein YP_916790.1 PFAM: transport system permease; KEGG: hch:HCH_03457 ABC-type enterobactin transport system, permease component YP_916791.1 PFAM: transport system permease; KEGG: pfl:PFL_3624 ferric vibriobactin ABC transporter, permease VC0777 YP_916792.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bur:Bcep18194_A4781 ABC cobalamin/Fe3+-siderophore transporter, ATPase subunit YP_916793.1 KEGG: pfl:PFL_3619 monooxygenase, NtaA/SnaA/SoxA family YP_916794.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Non-ribosomal peptide synthetase; KEGG: pen:PSEEN2503 non-ribosomal peptide synthetase BasA/D YP_916795.1 PFAM: phosphopantetheine-binding; KEGG: pen:PSEEN2505 2,3-dihydroxybenzoate-AMP ligase YP_916796.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: eci:UTI89_C2181 inner membrane ABC-transporter YP_916797.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1599 inner membrane ABC-transporter YbtQ YP_916798.1 PFAM: CBS domain containing protein; KEGG: lpf:lpl2035 hypothetical protein YP_916799.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mca:MCA1549 succinate dehydrogenase, hydrophobic membrane anchor protein YP_916800.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: aeh:Mlg_1332 succinate dehydrogenase, cytochrome b subunit YP_916801.1 KEGG: rru:Rru_A1205 succinate dehydrogenase/fumarate reductase iron-sulfur protein YP_916802.1 KEGG: rde:RD1_1693 hypothetical protein YP_916803.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: hne:HNE_1541 transcriptional regulator YP_916804.1 PFAM: protein of unknown function DUF542, ScdA domain protein; Hemerythrin HHE cation binding domain protein; KEGG: rso:RS02289 hypothetical protein YP_916805.1 KEGG: sil:SPOA0172 hypothetical protein YP_916806.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: nha:Nham_4301 alkylhydroperoxidase AhpD core YP_916807.1 PFAM: cytochrome c oxidase, subunit I; KEGG: rsp:RSP_1877 cytochrome c oxidase, aa3 type, subunit I YP_916808.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: ecp:ECP_2036 hypothetical TonB dependent receptor YP_916809.1 PFAM: Methyltransferase type 12; KEGG: dps:DP0853 hypothetical protein YP_916810.1 PFAM: transport system permease; KEGG: nha:Nham_0954 transport system permease YP_916811.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nwi:Nwi_2074 ABC transporter, ATPase subunit YP_916812.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3564 iron-chelating periplasmic-binding protein YP_916814.1 KEGG: rru:Rru_A1382 butyrate-acetoacetate CoA-transferase YP_916815.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: rsp:RSP_4197 antisigma-factor antagonist, STAS YP_916816.1 PFAM: Cl- channel, voltage-gated family protein; KEGG: mes:Meso_1046 Cl-channel, voltage gated YP_916817.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: rsp:RSP_3080 choline/carnitine/betaine transporter, BCCT family YP_916818.1 KEGG: pol:Bpro_5072 hypothetical protein YP_916819.1 KEGG: sil:SPOA0122 ISSpo9, transposase YP_916820.1 KEGG: bja:blr1867 hypothetical protein YP_916821.1 PFAM: major facilitator superfamily MFS_1; KEGG: bja:bll3850 multidrug resistance protein YP_916822.1 PFAM: major facilitator superfamily MFS_1; KEGG: stm:STM1545 multidrug efflux protein YP_916823.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: rpc:RPC_4092 alcohol dehydrogenase, zinc-binding YP_916824.1 PFAM: regulatory protein, MarR; KEGG: ret:RHE_CH02035 probable transcriptional regulator protein, MarR family YP_916825.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: ret:RHE_CH02034 probable monooxygenase YP_916826.1 PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: aeh:Mlg_2596 dehydrogenase, E1 component YP_916827.1 PFAM: regulatory proteins, IclR; KEGG: rha:RHA1_ro08622 probable transcriptional regulator, IclR family YP_916828.1 PFAM: Endoribonuclease L-PSP; KEGG: mlo:mlr1297 hypothetical protein YP_916829.1 PFAM: aminotransferase class-III; KEGG: pol:Bpro_0421 aminotransferase class-III YP_916830.1 PFAM: Amidase; KEGG: mxa:MXAN_2852 amidase family protein YP_916831.1 KEGG: sil:SPO2534 branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein YP_916832.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPO2533 branched-chain amino acid ABC transporter, ATP-binding protein YP_916833.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPO2532 branched-chain amino acid ABC transporter, ATP-binding protein YP_916834.1 PFAM: inner-membrane translocator; KEGG: sil:SPO2531 branched-chain amino acid ABC transporter, permease YP_916835.1 PFAM: inner-membrane translocator; KEGG: sil:SPO2530 branched-chain amino acid ABC transporter, permease YP_916836.1 PFAM: Amidase; KEGG: bxe:Bxe_B1011 indole acetamide hydrolase YP_916837.1 KEGG: gox:GOX2722 truncated transposase YP_916838.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein; KEGG: bbr:BB0916 autotransporter YP_916839.1 KEGG: mlo:mlr4672 hypothetical protein YP_916841.1 KEGG: zmo:ZMO0213 autotransporter YP_916842.1 PFAM: plasmid stabilization system; KEGG: rsp:RSP_3809 hypothetical protein YP_916843.1 KEGG: rsp:RSP_3810 hypothetical protein YP_916844.1 KEGG: mes:Meso_0525 hypothetical protein YP_916845.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: sit:TM1040_2078 protein of unknown function DUF6, transmembrane YP_916846.1 KEGG: bmb:BruAb1_1812 transcriptional regulator, LysR family YP_916848.1 catalyzes the conversion of citrate to isocitrate YP_916849.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein; KEGG: rso:RS05438 probable transcription regulator protein YP_916850.1 PFAM: protein of unknown function DUF112, transmembrane; KEGG: bja:blr3163 hypothetical protein YP_916851.1 KEGG: bja:blr3162 tricarboxylic transport membrane protein YP_916852.1 PFAM: Uncharacterized protein UPF0065; KEGG: bja:blr3161 tricarboxylic transport membrane protein YP_916853.1 KEGG: gme:Gmet_0306 CoA-binding protein YP_916854.1 KEGG: nwi:Nwi_0792 gene transfer agent (GTA) like protein YP_916855.1 KEGG: rde:RD1_0477 hypothetical protein YP_916856.1 PFAM: transposase IS200-family protein; KEGG: dra:DR1927 transposase YP_916857.1 KEGG: sil:SPO2736 hypothetical protein YP_916859.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein; KEGG: zmo:ZMO0213 autotransporter YP_916860.1 KEGG: rsp:RSP_2718 possible outer membrane protein YP_916861.1 KEGG: nwi:Nwi_1490 lipoprotein YP_916862.1 PFAM: protein of unknown function DUF1311; KEGG: pfo:Pfl_3894 protein of unknown function DUF1311 YP_916863.1 KEGG: sme:SMb21025 hypothetical protein YP_916864.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; KEGG: gbe:GbCGDNIH1_1769 glutamate-gated potassium channel YP_916865.1 KEGG: mlo:mll4938 hypothetical protein YP_916866.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: mes:Meso_3689 transcriptional regulator, AraC family YP_916868.1 PFAM: phage integrase family protein; KEGG: sit:TM1040_3585 phage integrase YP_916869.1 KEGG: rpe:RPE_2955 hypothetical protein YP_916870.1 KEGG: rsp:RSP_0491 hydrogen uptake histidine-kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_916871.1 PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: rsp:RSP_0492 hydrogenase small subunit YP_916872.1 PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rsp:RSP_0493 hydrogenase large subunit YP_916873.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; KEGG: rsp:RSP_0494 hydrogenase maturation factor F YP_916874.1 KEGG: rsp:RSP_0495 hydrogenase small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_916875.1 PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rsp:RSP_0496 hydrogenase large subunit YP_916876.1 PFAM: HupE/UreJ protein; KEGG: rsp:RSP_0497 HupE/UreJ accessory protein YP_916877.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: aeh:Mlg_2027 Ni/Fe-hydrogenase, b-type cytochrome subunit YP_916878.1 TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52, hydrogen uptake protein; KEGG: rsp:RSP_0499 HycI, hydrogenase maturation protease YP_916879.1 PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: rsp:RSP_0500 HupF/HypC hydrogenase YP_916880.1 PFAM: hydrogenase-1 expression HyaE; KEGG: rsp:RSP_0501 HupG hydrogenase expression/formation protein YP_916881.1 PFAM: HupH hydrogenase expression protein; KEGG: rsp:RSP_0502 HupH hydrogenase expression/formation protein YP_916882.1 PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: rsp:RSP_0503 HupJ, contains rubredoxin domain YP_916883.1 KEGG: rsp:RSP_0504 HupK YP_916884.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis, HypA; KEGG: rsp:RSP_0505 hydrogenase expression/synthesis, HypA family YP_916885.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: rsp:RSP_0506 NI2+-binding GTPase HypB YP_916886.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; KEGG: rsp:RSP_0507 HupR response regulator YP_916887.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: rsp:RSP_0508 hydrogenase expression/formation protein HypC YP_916888.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: rsp:RSP_0509 hydrogenase isoenzyme formation protein HypD YP_916889.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: rsp:RSP_0510 hydrogenase expression/formation protein HypE YP_916891.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: rha:RHA1_ro03326 possible CBS domain-containing protein YP_916892.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: nfa:nfa28250 hypothetical protein YP_916893.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: bxe:Bxe_C1385 transcriptional regulator, AraC family YP_916894.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mmc:Mmcs_1038 short-chain dehydrogenase/reductase SDR YP_916895.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_916896.1 PFAM: protein of unknown function UPF0074; Helix-turn-helix, type 11 domain protein; KEGG: rpb:RPB_3952 transcriptional regulator, BadM/Rrf2 family YP_916897.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rpb:RPB_3951 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_916898.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: rpb:RPB_3655 SAM binding protein YP_916899.1 PFAM: phage integrase family protein; KEGG: sit:TM1040_3585 phage integrase YP_916900.1 PFAM: Resolvase, N-terminal domain; Recombinase; KEGG: nha:Nham_3864 recombinase YP_916902.1 KEGG: rde:RD1_1995 hypothetical protein YP_916904.1 PFAM: Peptidase C24, Calicivirus polyprotein ORF 1; KEGG: rpd:RPD_2286 hypothetical protein YP_916905.1 KEGG: nar:Saro_2202 hypothetical protein YP_916906.1 PFAM: SMF family protein; KEGG: nar:Saro_2201 smf protein YP_916907.1 KEGG: nwi:Nwi_0831 phage integrase YP_916908.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: sme:SMc00808 chromate transport protein YP_916909.1 SMART: Rhodanese domain protein; KEGG: mlo:mlr5406 hypothetical protein YP_916910.1 PFAM: NADPH-dependent FMN reductase; KEGG: rsp:RSP_2731 arsenical resistance protein, ArsH YP_916911.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: sal:Sala_2405 arsenical-resistance protein YP_916912.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sal:Sala_2539 arsenate reductase YP_916913.1 PFAM: regulatory protein, ArsR; KEGG: nwi:Nwi_3123 transcriptional regulatory protein, ArsR family YP_916917.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: rsp:RSP_3621 cold-shock DNA-binding protein YP_916918.1 KEGG: rsp:RSP_3622 hypothetical protein YP_916920.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: sil:SPO3625 cold shock protein CspA YP_916922.1 PFAM: heat shock protein Hsp20; KEGG: ret:RHE_CH01244 probable molecular chaperone small heat shock protein, HSP20 family YP_916923.1 PFAM: heat shock protein Hsp20; KEGG: ret:RHE_CH01245 probable molecular chaperone small heat shock protein, HSP20 family YP_916924.1 KEGG: ret:RHE_CH01246 hypothetical protein YP_916925.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: nmu:Nmul_A0510 peptidase S1C, Do YP_916926.1 PFAM: Phytanoyl-CoA dioxygenase; KEGG: mxa:MXAN_4531 hypothetical protein YP_916927.1 PFAM: protein of unknown function DUF899, thioredoxin family protein; KEGG: pfo:Pfl_1441 protein of unknown function DUF899, thioredoxin-like YP_916928.1 PFAM: Tetratricopeptide TPR_4; KEGG: mes:Meso_0992 tetratricopeptide TPR_4 YP_916929.1 KEGG: mes:Meso_0991 hypothetical protein YP_916930.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: pol:Bpro_3707 cupin 2, conserved barrel YP_916931.1 PFAM: aminoglycoside 3-N-acetyltransferase; KEGG: gvi:gll0484 aminoglycoside N3'-acetyltransferase YP_916932.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:glr1626 hypothetical protein YP_916933.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: jan:Jann_4229 histone-like nucleoid-structuring protein H-NS YP_916934.1 PFAM: plasmid pRiA4b ORF-3 family protein; KEGG: sme:SMa0896 hypothetical protein YP_916936.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sal:Sala_0626 gentamicin 3'-N-acetyltransferase YP_916937.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_3955 transposase IS116/IS110/IS902 YP_916938.1 PFAM: transposase IS3/IS911 family protein; KEGG: nwi:Nwi_2119 transposase IS3/IS911 YP_916939.1 PFAM: Integrase, catalytic region; KEGG: nwi:Nwi_2120 integrase, catalytic region YP_916940.1 KEGG: mes:Meso_3831 hypothetical protein YP_916941.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: ret:RHE_CH01977 probable DNA-methyltransferase (hemagglutinin-associated protein) YP_916943.1 PFAM: protein of unknown function DUF81; KEGG: rsp:RSP_1646 possible transmembrane protein YP_916944.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: nha:Nham_4669 single-strand binding protein YP_916948.1 PFAM: helix-turn-helix domain protein; KEGG: ret:RHE_PA00165 transcriptional regulator protein YP_916949.1 KEGG: mes:Meso_0527 hypothetical protein YP_916950.1 KEGG: mes:Meso_0526 hypothetical protein YP_916951.1 KEGG: mes:Meso_0525 hypothetical protein YP_916952.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: sit:TM1040_2078 protein of unknown function DUF6, transmembrane YP_916953.1 KEGG: sme:SMc01177 hypothetical protein YP_916954.1 TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: sme:SMc01176 hypothetical protein YP_916955.1 KEGG: mes:Meso_3841 transcriptional regulator YP_916956.1 KEGG: mes:Meso_3842 replication protein A YP_916958.1 KEGG: mes:Meso_2334 hypothetical protein YP_916959.1 PFAM: C-5 cytosine-specific DNA methylase; KEGG: ngo:NGO1894 5-methylcytosine methyltransferase YP_916960.1 KEGG: mes:Meso_3845 conjugal transfer protein precursor YP_916961.1 PFAM: protein of unknown function DUF736; KEGG: mes:Meso_2332 protein of unknown function DUF736 YP_916962.1 PFAM: Lytic transglycosylase, catalytic; KEGG: mes:Meso_0517 lytic transglycosylase, catalytic YP_916964.1 KEGG: mes:Meso_3848 hypothetical protein YP_916965.1 type IV secretion VirD4 coupling protein family YP_916966.1 KEGG: mes:Meso_0514 helix-turn-helix protein, CopG YP_916967.1 KEGG: mxa:MXAN_3433 hypothetical protein YP_916969.1 PFAM: PilT protein domain protein; KEGG: plu:plu3057 hypothetical protein YP_916970.1 KEGG: ret:RHE_PE00297 plasmid stabilization protein YP_916971.1 PFAM: type II secretion system protein E; KEGG: mes:Meso_2324 type II secretion system protein E YP_916972.1 PFAM: Conjugal transfer protein TrbC; KEGG: mes:Meso_0508 conjugal transfer protein TrbC YP_916973.1 KEGG: mes:Meso_2322 conjugal transfer protein TrbB YP_916974.1 type IV secretion system VirB4 family YP_916975.1 KEGG: mes:Meso_3855 conjugal transfer protein TrbJ YP_916976.1 KEGG: mes:Meso_2319 hypothetical protein YP_916977.1 type IV secretion VirB6 family YP_916978.1 PFAM: Conjugal transfer protein; KEGG: mes:Meso_0502 conjugal transfer protein YP_916979.1 PFAM: Conjugal transfer protein TrbG/VirB9/CagX; KEGG: mes:Meso_0501 conjugal transfer protein TrbG/VirB9/CagX YP_916980.1 PFAM: conjugation TrbI family protein; KEGG: mes:Meso_0500 conjugation TrbI-like protein YP_916981.1 KEGG: rpc:RPC_3531 hypothetical protein YP_916982.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mes:Meso_3862 transcriptional regulator, LysR family YP_916983.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein; KEGG: bxe:Bxe_C0266 transcriptional regulator, GntR family YP_916984.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rpd:RPD_0611 TRAP dicarboxylate transporter-DctM subunit YP_916985.1 KEGG: rpd:RPD_0610 tripartite ATP-independent periplasmic transporter, DctQ component YP_916986.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: bja:bll6794 hypothetical protein YP_916987.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: bbr:BB0636 iron-containing alcohol dehydrogenase YP_916988.1 PFAM: aldehyde dehydrogenase; KEGG: rme:Rmet_1577 aldehyde dehydrogenase YP_916989.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sma:SAV3314 NADP-dependent alcohol dehydrogenase YP_916990.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bxe:Bxe_C0603 enoyl-CoA hydratase/isomerase YP_916992.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: sai:Saci_1814 carboxymuconolactone decarboxylase YP_916993.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: dar:Daro_3339 6-phosphogluconate dehydrogenase, NAD-binding YP_916994.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: sme:SMc01911 hypothetical protein YP_916995.1 PFAM: beta-lactamase domain protein; KEGG: bja:bll0351 hypothetical protein YP_916996.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: bja:bll6794 hypothetical protein YP_916997.1 PFAM: thioesterase superfamily protein; KEGG: rha:RHA1_ro00319 possible thioesterase YP_916998.1 PFAM: Uncharacterized protein UPF0065; KEGG: bbr:BB3965 hypothetical protein YP_916999.1 PFAM: protein of unknown function DUF112, transmembrane; KEGG: mes:Meso_2918 protein of unknown function DUF112, transmembrane YP_917000.1 PFAM: protein of unknown function DUF1468; KEGG: bpa:BPP0373 hypothetical protein YP_917001.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: abo:ABO_2098 acyl-CoA dehydrogenase YP_917002.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: rru:Rru_A1309 acetoacetyl-CoA reductase YP_917003.1 KEGG: rru:Rru_A1310 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase YP_917004.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rha:RHA1_ro00763 probable formyl-CoA transferase YP_917005.1 PFAM: aldehyde dehydrogenase; KEGG: bur:Bcep18194_C7342 aldehyde dehydrogenase YP_917006.1 KEGG: fal:FRAAL2833 hypothetical protein YP_917007.1 PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_3946 AMP-dependent synthetase and ligase YP_917008.1 KEGG: rha:RHA1_ro03060 probable transciptional regulator, IclR family YP_917009.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: mag:amb3346 signal transduction histidine kinase YP_917010.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_3955 transposase IS116/IS110/IS902 YP_917011.1 KEGG: yps:YPTB1994 hypothetical protein YP_917012.1 KEGG: mes:Meso_3912 hypothetical protein YP_917013.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; KEGG: mes:Meso_3897 NmrA-like YP_917014.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mes:Meso_3905 transcriptional regulator, LysR family YP_917015.1 KEGG: mes:Meso_3908 hypothetical protein YP_917016.1 KEGG: mes:Meso_3907 hypothetical protein YP_917017.1 KEGG: ade:Adeh_3220 hypothetical protein YP_917018.1 KEGG: mes:Meso_3899 twin-arginine translocation pathway signal YP_917019.1 PFAM: aldo/keto reductase; KEGG: bur:Bcep18194_B2855 aldo/keto reductase YP_917020.1 PFAM: aldo/keto reductase; KEGG: mes:Meso_3904 twin-arginine translocation pathway signal YP_917021.1 PFAM: aldo/keto reductase; KEGG: bxe:Bxe_B1949 aldo/keto reductase YP_917022.1 KEGG: mes:Meso_3911 hypothetical protein YP_917023.1 KEGG: nha:Nham_3076 transposase YP_917024.1 KEGG: mag:amb0411 transposase YP_917025.1 PFAM: regulatory proteins, IclR; KEGG: rha:RHA1_ro06686 probable transciptional regulator, IclR family YP_917026.1 PFAM: protein of unknown function DUF1468; KEGG: bpa:BPP0373 hypothetical protein YP_917027.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: dar:Daro_3230 alpha/beta hydrolase fold YP_917028.1 SMART: regulatory protein, MerR; KEGG: rsp:RSP_2201 transcriptional regulator, MerR family YP_917029.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1; KEGG: rsp:RSP_0945 major facilitator superfamily (MFS) transporter YP_917030.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: mes:Meso_2098 cupin 2, conserved barrel YP_917031.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: sth:STH938 3-hydroxyisobutyrate dehydrogenase YP_917032.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: pst:PSPTO_4478 4-carboxymuconolactone decarboxylase YP_917033.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rpd:RPD_0609 TRAP dicarboxylate transporter-DctP subunit YP_917034.1 KEGG: sme:SMa2189 integrase/recombinase YP_917035.1 PFAM: aldehyde dehydrogenase; KEGG: dra:DRA0126 aldehyde dehydrogenase YP_917036.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein; KEGG: atu:Atu5094 ISL3 family transposase YP_917038.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb20262 semialdehyde dehydrogenase YP_917039.1 KEGG: mes:Meso_2079 ABC transporter, periplasmic substrate-binding protein YP_917040.1 PFAM: Uncharacterized protein UPF0065; KEGG: dsy:DSY0976 hypothetical protein YP_917041.1 PFAM: amidohydrolase 2; KEGG: reu:Reut_B5784 amidohydrolase 2 YP_917042.1 PFAM: protein of unknown function DUF112, transmembrane; KEGG: bcl:ABC0625 hypothetical protein YP_917043.1 KEGG: bja:bll1020 hypothetical protein YP_917044.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1; KEGG: hne:HNE_1254 major facilitator family protein YP_917045.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: csa:Csal_0331 transcriptional regulator, LysR family YP_917046.1 PFAM: HpcH/HpaI aldolase; KEGG: sus:Acid_0199 HpcH/HpaI aldolase YP_917047.1 KEGG: bja:blr3843 hypothetical protein YP_917048.1 PFAM: amidohydrolase 2; KEGG: rme:Rmet_3705 amidohydrolase 2 YP_917049.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: bms:BRA0945 acetolactate synthase large subunit YP_917051.1 PFAM: amidohydrolase 2; KEGG: reu:Reut_B5784 amidohydrolase 2 YP_917052.1 KEGG: bja:blr3843 hypothetical protein YP_917053.1 KEGG: sil:SPO3430 outer membrane porin YP_917054.1 PFAM: Integrase, catalytic region; KEGG: rsp:RSP_3937 probable transposase, Y4bF YP_917055.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein; KEGG: atu:Atu5094 ISL3 family transposase YP_917057.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_3975 periplasmic sensor signal transduction histidine kinase YP_917058.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bmb:BruAb2_0224 two component response regulator YP_917059.1 KEGG: rsp:RSP_7166 hypothetical protein YP_917060.1 PFAM: cytochrome B561; KEGG: rsp:RSP_2807 cytochrome b YP_917061.1 KEGG: bmb:BruAb1_1622 hypothetical protein YP_917062.1 KEGG: bma:BMAA0783 hypothetical protein YP_917063.1 KEGG: bmb:BruAb2_0227 hypothetical protein YP_917064.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; Oxidoreductase FAD-binding domain protein; KEGG: bms:BRA0233 oxidoreductase, FAD-binding YP_917065.1 PFAM: ApbE family lipoprotein; KEGG: bmb:BruAb2_0229 ApbE family protein YP_917066.1 KEGG: dar:Daro_1035 hypothetical protein YP_917067.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rsp:RSP_3052 transcriptional regulator, LysR family YP_917068.1 PFAM: Heavy metal transport/detoxification protein; KEGG: rxy:Rxyl_1802 heavy metal transport/detoxification protein YP_917069.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: rxy:Rxyl_1801 heavy metal translocating P-type ATPase YP_917070.1 PFAM: protein of unknown function DUF924; KEGG: gvi:glr1115 hypothetical protein YP_917071.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: nwi:Nwi_1949 heavy metal translocating P-type ATPase YP_917072.1 KEGG: sat:SYN_02345 hypothetical membrane protein YP_917073.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mag:amb2540 ABC-type antimicrobial peptide transport system, ATPase component YP_917074.1 PFAM: protein of unknown function DUF214; KEGG: mag:amb2541 ABC-type antimicrobial peptide transport system, permease component YP_917075.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: mag:amb2542 membrane-fusion protein YP_917076.1 PFAM: regulatory protein, TetR; KEGG: eba:ebA6247 transcriptional regulator, TetR family YP_917077.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: atc:AGR_pAT_51 hypothetical protein YP_917078.1 KEGG: bja:blr1867 hypothetical protein YP_917079.1 PFAM: transposase IS66; KEGG: bja:blr1700 transposase YP_917080.1 PFAM: IS66 Orf2 family protein; KEGG: bja:bll2160 transposase YP_917081.1 PFAM: transposase IS3/IS911 family protein; KEGG: atc:AGR_pTi_30 hypothetical protein YP_917082.1 KEGG: sme:SMb21085 hypothetical protein encoded by ORF3 of ISRm14, IS66 family YP_917083.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: rpd:RPD_3866 response regulator receiver YP_917084.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: ret:RHE_PF00324 probable two-component sensor histidine kinase/response regulator hybrid protein YP_917085.1 KEGG: rde:RD1_3578 hypothetical protein YP_917091.1 KEGG: mlo:mlr7467 hypothetical protein YP_917092.1 PFAM: von Willebrand factor, type A; KEGG: jan:Jann_1721 von Willebrand factor, type A YP_917096.1 KEGG: rpe:RPE_0562 type III restriction enzyme, res subunit YP_917097.1 KEGG: rfr:Rfer_4292 hypothetical protein YP_917098.1 PFAM: Resolvase, N-terminal domain; Recombinase; KEGG: nha:Nham_3864 recombinase YP_917100.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: rsp:RSP_3202 transcriptional regulator, AraC family YP_917102.1 KEGG: bxe:Bxe_A0212 hypothetical protein YP_917103.1 PFAM: transposase, IS4 family protein; KEGG: sil:SPOA0134 ISSpo7, transposase YP_917105.1 PFAM: SH3, type 3 domain protein; KEGG: rsp:RSP_6161 hypothetical protein YP_917107.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: sme:SMc00808 chromate transport protein YP_917108.1 SMART: Rhodanese domain protein; KEGG: mlo:mlr5406 hypothetical protein YP_917109.1 PFAM: NADPH-dependent FMN reductase; KEGG: rsp:RSP_2731 arsenical resistance protein, ArsH YP_917110.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: sal:Sala_2405 arsenical-resistance protein YP_917111.1 TIGRFAM: arsenate reductase; PFAM: low molecular weight phosphotyrosine protein phosphatase; arsenate reductase and related; KEGG: nwi:Nwi_3124 low molecular weight phosphotyrosine protein phosphatase YP_917112.1 PFAM: regulatory protein, ArsR; KEGG: nwi:Nwi_3123 transcriptional regulatory protein, ArsR family YP_917113.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: rsp:RSP_4197 antisigma-factor antagonist, STAS YP_917114.1 PFAM: protein of unknown function DUF1127; KEGG: rde:RD1_2086 hypothetical protein YP_917116.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mlo:mlr1197 hypothetical protein YP_917117.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: gvi:glr1626 hypothetical protein YP_917118.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: jan:Jann_4229 histone-like nucleoid-structuring protein H-NS YP_917119.1 PFAM: plasmid pRiA4b ORF-3 family protein; KEGG: sme:SMa0896 hypothetical protein YP_917120.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: bja:blr0060 hypothetical protein YP_917121.1 PFAM: protein of unknown function DUF156; KEGG: atc:AGR_C_1623 hypothetical protein YP_917122.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: sme:SMc04167 histidine-rich transporter transmembrane protein YP_917124.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sal:Sala_0626 gentamicin 3'-N-acetyltransferase YP_917125.1 KEGG: mes:Meso_3831 hypothetical protein YP_917126.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: nha:Nham_0569 DNA methylase N-4/N-6 YP_917128.1 PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_L_1711 acetyltransferase YP_917130.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: nha:Nham_4669 single-strand binding protein YP_917134.1 KEGG: mes:Meso_3838 hypothetical protein YP_917136.1 KEGG: nwi:Nwi_0844 hypothetical protein YP_917137.1 PFAM: helix-turn-helix domain protein; KEGG: mlo:msr6108 transcriptional regulator YP_917138.1 KEGG: nwi:Nwi_0845 hypothetical protein YP_917139.1 KEGG: nwi:Nwi_0846 possible replication protein A YP_917140.1 KEGG: mes:Meso_2334 hypothetical protein YP_917141.1 PFAM: C-5 cytosine-specific DNA methylase; KEGG: ngo:NGO1894 5-methylcytosine methyltransferase YP_917142.1 KEGG: mes:Meso_2333 conjugal transfer protein precursor YP_917143.1 PFAM: protein of unknown function DUF736; KEGG: mes:Meso_2332 protein of unknown function DUF736 YP_917144.1 PFAM: Lytic transglycosylase, catalytic; KEGG: mes:Meso_0517 lytic transglycosylase, catalytic YP_917146.1 KEGG: bja:bll0044 hypothetical protein YP_917147.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: rru:Rru_A0090 prevent-host-death protein YP_917148.1 PFAM: PilT protein domain protein; KEGG: rru:Rru_A0091 PilT protein-like YP_917149.1 KEGG: nmu:Nmul_A0143 ATP-dependent endonuclease of the OLD family-like YP_917150.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: rsp:RSP_3202 transcriptional regulator, AraC family YP_917151.1 PFAM: class II aldolase/adducin family protein; KEGG: bja:bll2927 hypothetical protein YP_917152.1 PFAM: type III effector Hrp-dependent outers; KEGG: reu:Reut_A1426 type III effector Hrp-dependent outers YP_917153.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: gka:GK1972 transporter YP_917154.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: msu:MS0052 hypothetical protein YP_917155.1 PFAM: cyclase family protein; KEGG: pmu:PM1641 hypothetical Synechocystis sp. YP_917156.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0762 possible C4-dicarboxylate transport system, periplasmic component YP_917157.1 PFAM: SAF domain; KEGG: rru:Rru_A3141 homoserine dehydrogenase, NAD-binding YP_917158.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sme:SMb20773 transcriptional regulator, GntR family protein YP_917159.1 KEGG: ade:Adeh_3797 hypothetical protein YP_917162.1 KEGG: sal:Sala_0067 transposase YP_917163.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: abo:ABO_1099 transcriptional regulator, LysR family YP_917165.1 KEGG: rpb:RPB_3880 twin-arginine translocation pathway signal YP_917166.1 PFAM: Ferric reductase domain protein transmembrane component, N-terminal domain; KEGG: rde:RD1_1724 hypothetical protein YP_917167.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain IV; KEGG: rru:Rru_A2222 molybdopterin biosynthesis protein YP_917168.1 KEGG: nwi:Nwi_2919 transposase, IS4 YP_917169.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rfr:Rfer_3645 periplasmic sensor signal transduction histidine kinase YP_917170.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rfr:Rfer_3646 two component transcriptional regulator, winged helix family YP_917171.1 PFAM: extracellular solute-binding protein, family 1; KEGG: pub:SAR11_0769 probable binding protein component of ABC sugar transporter YP_917172.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rru:Rru_A0093 binding-protein-dependent transport systems inner membrane component YP_917173.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rru:Rru_A0094 binding-protein-dependent transport systems inner membrane component YP_917174.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMc04393 ATP-binding ABC transporter protein YP_917176.1 PFAM: creatinase; peptidase M24; KEGG: ppu:PP_3667 creatinase YP_917177.1 KEGG: rxy:Rxyl_0459 creatininase YP_917178.1 KEGG: ccr:CC1457 flagellin modification protein FlmG YP_917181.1 KEGG: rpa:RPA2826 hypothetical protein YP_917182.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: atc:AGR_pAT_469 hypothetical protein YP_917183.1 PFAM: Acetamidase/Formamidase; KEGG: rsp:RSP_3443 acetamidase/formamidase YP_917185.1 PFAM: Dimethylmenaquinone methyltransferase; KEGG: rsp:RSP_3441 hypothetical protein YP_917186.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_3440 short chain dehydrogenase YP_917187.1 PFAM: aminotransferase, class I and II; KEGG: rsp:RSP_3439 aspartate aminotransferase YP_917188.1 PFAM: Endoribonuclease L-PSP; KEGG: rsp:RSP_3438 translation initiation inhibitor YP_917189.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_917190.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rsp:RSP_3436 transcriptional regulator, LysR-family YP_917191.1 PFAM: dihydrodipicolinate synthetase; KEGG: rsp:RSP_3456 dihydrodipicolinate synthase YP_917192.1 PFAM: aminotransferase, class IV; KEGG: rsp:RSP_3455 D-alanine aminotransferase YP_917193.1 PFAM: LamB/YcsF family protein; KEGG: rsp:RSP_3454 hypothetical protein YP_917194.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rsp:RSP_3453 TRAP-T family transporter, periplasmic binding protein YP_917195.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: rsp:RSP_3452 TRAP-T family transporter, small (4TMs) inner membrane subunit YP_917196.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rsp:RSP_3451 TRAP-T family transporter, large (12TMs) inner membrane subunit YP_917197.1 PFAM: Allophanate hydrolase subunit 1; KEGG: rsp:RSP_3450 hypothetical protein YP_917198.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: rsp:RSP_3449 allophanate hydrolase subunit 2 YP_917199.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: rsp:RSP_3448 transcriptional regulator, GntR-family YP_917200.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: rsp:RSP_3447 dehydrogenase YP_917201.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_917202.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: rsp:RSP_3445 transcriptional regulator, GntR family YP_917203.1 PFAM: peptidase M24; KEGG: rsp:RSP_3444 Xaa-Pro aminopeptidase YP_917204.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: jan:Jann_2909 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_917205.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: rpc:RPC_3026 histidine kinase YP_917206.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rpc:RPC_3029 two component transcriptional regulator, winged helix family YP_917211.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: rpb:RPB_2235 hypothetical protein YP_917212.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rpc:RPC_1868 secretion protein HlyD YP_917214.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ret:RHE_CH03411 probable protein secretion protein, HlyD family YP_917215.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: ret:RHE_CH03412 probable multidrug efflux transporter protein YP_917216.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: ret:RHE_CH03413 nodulation protein (outer membrane efflux protein) YP_917217.1 PFAM: beta-lactamase; KEGG: rsp:RSP_3749 beta-lactamase precursor YP_917218.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sme:SMa2293 probable beta lactamase transcriptional activator YP_917221.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rde:RD1_4140 transcriptional regulator, LysR family YP_917222.1 PFAM: protein of unknown function DUF1028; KEGG: rde:RD1_4139 hypothetical protein YP_917223.1 PFAM: Endoribonuclease L-PSP; KEGG: rde:RD1_4138 endoribonuclease L-PSP family protein YP_917224.1 PFAM: FAD dependent oxidoreductase; KEGG: pau:PA14_71210 monooxygenase YP_917225.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_917226.1 KEGG: rsp:RSP_1882 ABC polyamine/opine transporter, ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_917227.1 KEGG: rsp:RSP_1883 ABC polyamine/opine transporter, periplasmic substrate-binding protein YP_917228.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_1884 ABC polyamine/opine transporter, inner membrane subunit YP_917229.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_1886 ABC polyamine/opine transporter, inner membrane subunit YP_917230.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sil:SPO3737 pyridine nucleotide-disulphide oxidoreductase family protein YP_917231.1 PFAM: ferredoxin; KEGG: sil:SPO0766 iron-sulfur cluster-binding protein YP_917232.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: bxe:Bxe_A3468 iron-sulphur rieske protein YP_917233.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: csa:Csal_2385 transcriptional regulator, LysR family YP_917234.1 PFAM: proline racemase; KEGG: atc:AGR_L_1800 hypothetical protein YP_917235.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: sil:SPOA0206 transcriptional regulator, Crp/Fnr family YP_917236.1 KEGG: ade:Adeh_2705 response regulator receiver YP_917237.1 KEGG: ret:RHE_PC00193 hypothetical protein YP_917238.1 PFAM: TfuA domain protein, core; KEGG: mxa:MXAN_2398 hypothetical protein YP_917239.1 TIGRFAM: uncharacterized domain; PFAM: protein of unknown function DUF181; KEGG: ret:RHE_PE00437 hypothetical protein YP_917240.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: mlo:mll3276 adenylate cyclase cya3 [Sinorhizobium meliloti] YP_917241.1 PFAM: protein of unknown function DUF839; KEGG: rsp:RSP_3051 phosphatase YP_917242.1 PFAM: ThiJ/PfpI domain protein; KEGG: bms:BRA0227 ThiJ/PfpI family protein YP_917243.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: ccr:CC3083 FMN oxidoreductase YP_917244.1 PFAM: regulatory protein, MerR; KEGG: ccr:CC3082 transcriptional regulator, MerR family YP_917245.1 PFAM: regulatory proteins, IclR; KEGG: rpc:RPC_0118 transcriptional regulator, IclR family YP_917246.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: gka:GK1971 C4-dicarboxylate transport system (C4-dicarboxylate-binding protein) YP_917247.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: dvu:DVU0010 TRAP transporter, DctQ subunit YP_917248.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: csa:Csal_2978 TRAP dicarboxylate transporter-DctM subunit YP_917249.1 PFAM: dihydroorotate dehydrogenase; KEGG: tac:Ta0404 dihydroorotate oxidase YP_917250.1 KEGG: pol:Bpro_3857 hypothetical protein YP_917251.1 PFAM: HpcH/HpaI aldolase; KEGG: bxe:Bxe_C0507 HpcH/HpaI aldolase YP_917252.1 KEGG: rpc:RPC_0116 hypothetical protein YP_917253.1 PFAM: regulatory protein, MarR; KEGG: bja:bll4221 transcriptional regulatory protein YP_917254.1 catalyzes the formation of catechol from phenol YP_917255.1 TIGRFAM: pca operon transcription factor PcaQ; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sil:SPOA0047 pca operon transcriptional activator PcaQ YP_917256.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_917257.1 TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; KEGG: jan:Jann_1663 3-oxoadipate enol-lactonase YP_917258.1 TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase; KEGG: sit:TM1040_0559 4-carboxymuconolactone decarboxylase YP_917259.1 TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase; KEGG: sil:SPOA0044 protocatechuate 3,4-dioxygenase beta subunit YP_917260.1 KEGG: sil:SPOA0043 protocatechuate 3,4-dioxygenase alpha subunit; TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase YP_917261.1 PFAM: protein of unknown function DUF849; KEGG: sil:SPOA0042 hypothetical protein YP_917262.1 PFAM: fumarate lyase; KEGG: sil:SPOA0432 3-carboxy-cis,cis-muconate cycloisomerase YP_917263.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: eba:ebA5362 predicted TRAP dicarboxylate transporter, DctP subunit YP_917264.1 KEGG: eba:ebB188 hypothetical protein YP_917265.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: eba:ebA5367 conserved hypothetical protein, predicted TRAP C4-dicarboxylate transport system permease DctM subunit,DedA falily YP_917266.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: atc:AGR_L_1754 hypothetical protein YP_917267.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: atc:AGR_L_1752 hypothetical protein YP_917268.1 KEGG: rde:RD1_A0097 RC150 YP_917269.1 PFAM: protein of unknown function DUF1427; KEGG: rde:RD1_A0096 hypothetical protein YP_917270.1 PFAM: isochorismatase hydrolase; KEGG: rde:RD1_A0094 hydrolase YP_917271.1 KEGG: rde:RD1_A0090 hypothetical protein YP_917272.1 KEGG: reu:Reut_B4847 DoxX YP_917273.1 PFAM: Amidohydrolase 3; KEGG: reu:Reut_B4849 conserved hypothetical protein PA2699 YP_917274.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1; KEGG: tbd:Tbd_1578 probable MFS transporter YP_917275.1 PFAM: DoxX family protein; KEGG: mes:Meso_0934 DoxX YP_917276.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: sit:TM1040_1889 pirin-like YP_917277.1 KEGG: bbr:BB2355 hypothetical protein YP_917278.1 PFAM: regulatory protein, MarR; KEGG: gme:Gmet_0359 transcriptional regulator, MarR family YP_917279.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mes:Meso_2630 transcriptional regulator, LysR family YP_917280.1 PFAM: amidohydrolase; KEGG: mes:Meso_2641 amidohydrolase YP_917281.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_917282.1 PFAM: protein of unknown function DUF917; KEGG: mes:Meso_2639 protein of unknown function DUF917 YP_917283.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_917284.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bur:Bcep18194_B3017 major facilitator superfamily (MFS_1) transporter YP_917285.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: son:SO3057 Pal/histidase family protein YP_917286.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: sme:SMa1749 transcriptional regulator YP_917287.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sme:SMa1747 ferrichrome-iron receptor YP_917288.1 PFAM: periplasmic binding protein; KEGG: rsp:RSP_3416 ABC Fe+3-siderophore transporter, periplasmic binding protein YP_917289.1 PFAM: transport system permease; KEGG: sme:SMa1745 iron uptake protein YP_917290.1 PFAM: transport system permease; KEGG: sme:SMa1742 iron uptake protein YP_917291.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_3413 ABC Fe+3-siderophore transporter, ATPase subunit YP_917292.1 KEGG: pae:PA4155 hypothetical protein YP_917293.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rpb:RPB_2695 TonB-dependent receptor YP_917294.1 PFAM: regulatory proteins, IclR; KEGG: pfl:PFL_3621 transcriptional regulator, IclR family YP_917295.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pau:PA14_10180 ferric enterobactin transport protein FepC YP_917296.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: cgb:cg0054 iron-chelator utilization protein YP_917297.1 with FepCDG is involved in the transport of ferric enterobactin YP_917298.1 PFAM: transport system permease; KEGG: pfl:PFL_3624 ferric vibriobactin ABC transporter, permease VC0777 YP_917299.1 PFAM: transport system permease; KEGG: pfl:PFL_3624 ferric vibriobactin ABC transporter, permease VC0777 YP_917300.1 PFAM: transport system permease; KEGG: pfl:PFL_3625 ferric vibriobactin ABC transporter, permease VC0778 YP_917301.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: sil:SPO0270 glutathione S-transferase family protein YP_917302.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: pau:PA14_64820 transcriptional regulator YP_917303.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: mes:Meso_3712 short-chain dehydrogenase/reductase SDR YP_917304.1 KEGG: rsp:RSP_0635 TRAP-T family transporter, DctQ (4 TMs) subunit YP_917305.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rsp:RSP_0634 TRAP-T family transporter, DctM (12 TMs) subunit YP_917306.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rsp:RSP_0636 TRAP-T family transporter, DctP (periplasmic binding) subunit YP_917307.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: bxe:Bxe_A1074 3-oxoacyl-(acyl-carrier-protein) reductase YP_917308.1 PFAM: short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KEGG: bur:Bcep18194_C7123 short-chain dehydrogenase/reductase SDR YP_917309.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: bja:blr6805 dehydrogenase YP_917311.1 PFAM: regulatory protein, MarR; KEGG: mlo:mll8302 transcriptional regulator YP_917312.1 PFAM: regulatory protein, MarR; KEGG: rde:RD1_3650 transcriptional regulator MarR/EmrR family YP_917313.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_917314.1 KEGG: sit:TM1040_2622 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase YP_917315.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; KEGG: sme:SMc03206 maleylacetoacetate isomerase (glutathione transferase ZETA 1) protein YP_917316.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: aeh:Mlg_2324 acylneuraminate cytidylyltransferase YP_917317.1 KEGG: ccr:CC2854 flagellin modification protein FlmD YP_917318.1 PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; KEGG: bce:BC5272 carbamoyl-phosphate synthase small chain YP_917319.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: sth:STH781 UDP-glucose 4-epimerase YP_917322.1 PFAM: N-acetylneuraminic acid synthase, N-terminal domain; SAF domain; KEGG: mhu:Mhun_3098 N-acylneuraminate-9-phosphate synthase YP_917323.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: aeh:Mlg_2323 DegT/DnrJ/EryC1/StrS aminotransferase YP_917324.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: son:SO3271 polysaccharide biosynthesis protein YP_917325.1 KEGG: rso:RS01910 probable transport transmembrane protein YP_917326.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_3955 transposase IS116/IS110/IS902 YP_917327.1 PFAM: transposase IS3/IS911 family protein; KEGG: nwi:Nwi_2119 transposase IS3/IS911 YP_917329.1 KEGG: rsp:RSP_0396 hypothetical protein YP_917330.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bja:blr6651 two-component response regulator YP_917331.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: mxa:MXAN_4244 sensor histidine kinase / response regulator YP_917332.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: pst:PSPTO_4079 sensor histidine kinase/response regulator YP_917333.1 PFAM: Acetamidase/Formamidase; KEGG: bbr:BB1405 formamidase YP_917334.1 PFAM: AmiS/UreI transporter; KEGG: bpa:BPP1188 transporter protein YP_917335.1 KEGG: abo:ABO_1977 hypothetical protein YP_917336.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: bcn:Bcen_4032 short-chain dehydrogenase/reductase SDR YP_917337.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: reu:Reut_C6220 regulatory protein GntR, HTH:GntR, C-terminal YP_917338.1 KEGG: rso:RS05343 hypothetical protein YP_917339.1 PFAM: inner-membrane translocator; KEGG: bja:bll3662 ABC transporter permease YP_917340.1 PFAM: inner-membrane translocator; ABC transporter related; SMART: AAA ATPase; KEGG: bja:bll3661 ABC transporter ATP-binding/permease YP_917341.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: rsp:RSP_3970 3-hydroxybutyryl-CoA dehydrogenase YP_917342.1 PFAM: protein of unknown function DUF849; KEGG: rde:RD1_4158 hypothetical protein YP_917343.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_917344.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: bxe:Bxe_C0308 short-chain dehydrogenase/reductase YP_917346.1 PFAM: regulatory protein, LuxR; Sigma-70, region 4 type 2; KEGG: sme:SMc01630 transcription regulator protein YP_917347.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sme:SMc00778 oxidoreductase YP_917348.1 TIGRFAM: FAD-linked oxidoreductase; PFAM: FAD linked oxidase domain protein; KEGG: sme:SMc00779 FAD-dependent oxidoreductase YP_917349.1 PFAM: Ethanolamine utilisation protein, EutH; KEGG: pfl:PFL_5470 ethanolamine utilization protein EutH YP_917350.1 PFAM: transglutaminase domain protein; KEGG: eba:ebA3478 predicted transglutaminase-like enzyme, cysteine protease YP_917351.1 KEGG: atc:AGR_L_572 hypothetical protein YP_917352.1 PFAM: amidohydrolase; KEGG: sus:Acid_5787 amidohydrolase YP_917355.1 TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: sme:SMa0471 DNA-damage-inducibile protein YP_917356.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: plu:plu2210 hypothetical protein YP_917357.1 PFAM: transposase IS66; KEGG: mag:amb3320 transposase and inactivated derivative YP_917358.1 PFAM: IS66 Orf2 family protein; KEGG: pol:Bpro_5536 IS66 Orf2 like YP_917359.1 TIGRFAM: phage tape measure protein; KEGG: nwi:Nwi_1471 hypothetical protein YP_917364.1 PFAM: Fibronectin, type III domain protein; KEGG: mlo:mlr8544 hypothetical protein YP_917365.1 KEGG: mlo:mlr8029 hypothetical protein YP_917369.1 PFAM: glycoside hydrolase, family 19; Peptidoglycan-binding domain 1 protein; KEGG: sme:SMb20518 hypothetical protein YP_917372.1 KEGG: rsp:RSP_2806 probable ATP-dependent protease La protein; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_917373.1 PFAM: CsbD family protein; KEGG: rpb:RPB_1394 CsbD-like YP_917374.1 KEGG: sit:TM1040_0586 conserved hypothetical protein YP_917375.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_917376.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: jan:Jann_3466 monooxygenase, FAD-binding YP_917377.1 KEGG: sil:SPO3139 hypothetical protein YP_917378.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: jan:Jann_0570 glyoxalase/bleomycin resistance protein/dioxygenase YP_917379.1 PFAM: protein of unknown function UPF0126; KEGG: sil:SPO3213 hypothetical protein YP_917380.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_917381.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: bmb:BruAb1_1487 glutathione S-transferase family protein YP_917382.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_917383.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_917384.1 KEGG: sit:TM1040_2319 conserved hypothetical protein YP_917385.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sil:SPO3055 acetyltransferase, GNAT family YP_917386.1 inactivates vertebrate C-type lysozyme YP_917387.1 KEGG: rde:RD1_2154 hypothetical protein YP_917388.1 SMART: AAA ATPase; KEGG: jan:Jann_0847 ATPase YP_917389.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: rde:RD1_1000 transcriptional regulator, AsnC family YP_917390.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sal:Sala_1362 lysine exporter protein (LysE/YggA) YP_917391.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: rpe:RPE_0156 protein of unknown function DUF6, transmembrane YP_917392.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_917393.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_917394.1 TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; KEGG: rsp:RSP_0430 cobalamin biosynthesis protein CobD YP_917395.1 PFAM: Phosphoglycerate mutase; KEGG: rpa:RPA0993 possible alpha-ribazole-5'-phosphate phosphatase CobC (vit B12 synthesis) YP_917396.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sil:SPO2793 isovaleryl-CoA dehydrogenase YP_917397.1 PFAM: protein of unknown function DUF1311; KEGG: mmr:Mmar10_1738 protein of unknown function DUF1311 YP_917398.1 PFAM: protein of unknown function DUF1311 YP_917399.1 PFAM: OmpW family protein; KEGG: xcb:XC_0970 outer membrane protein YP_917400.1 PFAM: carboxyl transferase; KEGG: sit:TM1040_0737 propionyl-CoA carboxylase YP_917401.1 PFAM: Appr-1-p processing domain protein; KEGG: cvi:CV3563 hypothetical protein YP_917402.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: jan:Jann_1147 carbamoyl-phosphate synthase L chain, ATP-binding YP_917403.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: jan:Jann_1148 glutathione S-transferase-like YP_917404.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_917405.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_917406.1 PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr4870 MFS permease YP_917407.1 KEGG: rde:RD1_0624 hypothetical protein YP_917408.1 PFAM: protein of unknown function DUF465; KEGG: bms:BRA0175 hypothetical protein YP_917409.1 PFAM: heat shock protein Hsp20; KEGG: sil:SPO3484 heat shock protein, Hsp20 family YP_917410.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_917411.1 PFAM: conserved hypothetical protein 103; KEGG: jan:Jann_3877 conserved hypothetical protein 103 YP_917412.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_917413.1 KEGG: bmb:BruAb1_1279 hypothetical protein YP_917414.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_917415.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2717 UUP ATPase YP_917416.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: rsp:RSP_1952 cold-shock DNA-binding domain protein YP_917417.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_917418.1 PFAM: glycosyl transferase, group 1; KEGG: jan:Jann_4272 glycosyl transferase, group 1 YP_917419.1 PFAM: GumN family protein; KEGG: rsp:RSP_2309 hypothetical protein YP_917420.1 KEGG: sme:SMc01433 hypothetical protein YP_917421.1 PFAM: protein of unknown function DUF1345; KEGG: sme:SMc01272 hypothetical protein YP_917422.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_917423.1 TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein; HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rsp:RSP_2306 HAD superfamily protein YP_917424.1 PFAM: MaoC domain protein dehydratase; KEGG: rsp:RSP_2305 MaoC family protein YP_917425.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: rsp:RSP_2304 riboflavin kinase / FAD synthetase = FMN adenylyltransferase, RibF YP_917426.1 PFAM: protein of unknown function UPF0153; KEGG: sil:SPO3155 hypothetical protein YP_917427.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rsp:RSP_2302 low specificity L-threonine aldolase YP_917428.1 PFAM: CinA domain protein; KEGG: rde:RD1_2769 competence/damage-inducible protein CinA YP_917429.1 PFAM: phosphatidylglycerophosphatase A; KEGG: rde:RD1_2768 phosphatidylglycerophosphatase A YP_917430.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MECDP-synthase; KEGG: sil:SPO2090 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_917431.1 KEGG: rsp:RSP_0359 ribose-5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase; PFAM: Ribose 5-phosphate isomerase YP_917432.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rsp:RSP_0358 probable glutathione reductase YP_917433.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: rsp:RSP_0357 probable HflK protein YP_917434.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: rsp:RSP_0356 probable HflC protein YP_917435.1 PFAM: protein of unknown function UPF0118; KEGG: rsp:RSP_1564 transmembrane transport protein YP_917436.1 PFAM: TENA/THI-4 domain protein; KEGG: ppu:PP_3185 pet18 protein YP_917437.1 PFAM: NUDIX hydrolase; KEGG: sco:SCO5600 hypothetical protein YP_917438.1 KEGG: sit:TM1040_0507 conserved hypothetical protein YP_917439.1 PFAM: protein of unknown function DUF45; KEGG: rsp:RSP_0982 zinc metallopeptidase-like protein YP_917440.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: rsp:RSP_0981 transcriptional regulator, GntR family YP_917441.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_917442.1 KEGG: syf:Synpcc7942_1655 hypothetical protein YP_917443.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_0784 acetyltransferase, GNAT family YP_917444.1 MDM; functions in conversion of succinate to propionate YP_917445.1 KEGG: sil:SPO1103 hypothetical protein YP_917447.1 PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: sil:SPO1101 propionyl-CoA carboxylase, alpha subunit YP_917449.1 KEGG: rsp:RSP_2190 hypothetical protein YP_917450.1 KEGG: rsp:RSP_6040 hypothetical protein YP_917451.1 PFAM: carboxyl transferase; KEGG: rsp:RSP_2189 propionyl-CoA carboxylase beta chain YP_917452.1 KEGG: sil:SPO2670 alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein YP_917453.1 PFAM: protein of unknown function DUF140; KEGG: rsp:RSP_2459 ABC transporter, inner membrane subunit YP_917454.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2458 ABC transporter, ATPase subunit YP_917455.1 PFAM: PhoH family protein; KEGG: rsp:RSP_3599 hypothetical protein YP_917456.1 PFAM: protein of unknown function UPF0054; KEGG: rsp:RSP_3598 hypothetical protein YP_917457.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: rsp:RSP_3597 CorC/HlyC family protein with CBS domains YP_917458.1 PFAM: GCN5-related N-acetyltransferase; Antibiotic biosynthesis monooxygenase; KEGG: aba:Acid345_3954 GCN5-related N-acetyltransferase YP_917459.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_917460.1 PFAM: thiamine monophosphate synthase; KEGG: rsp:RSP_3828 thiamine-phosphate pyrophosphorylase YP_917461.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: rsp:RSP_3829 tRNA/rRNA methyltransferase (SpoU) YP_917462.1 PFAM: cytochrome oxidase assembly; KEGG: sit:TM1040_1335 cytochrome oxidase assembly YP_917463.1 PFAM: peptidase M32, carboxypeptidase Taq metallopeptidase; KEGG: rsp:RSP_3832 thermostable carboxypeptidase 1 YP_917464.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_917465.1 PFAM: glutamine synthetase, catalytic region; KEGG: rsp:RSP_0375 probable glutamine synthetase YP_917466.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0374 ABC basic amino acid transporter, inner membrane subunit YP_917467.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sit:TM1040_1713 binding-protein-dependent transport systems inner membrane component YP_917468.1 PFAM: extracellular solute-binding protein, family 3; KEGG: sil:SPO1306 His/Glu/Gln/Arg/opine family ABC transporter, periplasmic His/Glu/Gln/Arg/opine family-binding protein YP_917469.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_0371 ABC basic amino acid transporter, ATPase subunit YP_917470.1 PFAM: protein of unknown function DUF1332; KEGG: sil:SPO1309 hypothetical protein YP_917471.1 PFAM: protein of unknown function DUF1330; KEGG: sit:TM1040_1707 protein of unknown function DUF1330 YP_917472.1 PFAM: protein of unknown function DUF344; KEGG: sme:SMa0172 hypothetical protein YP_917474.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_917475.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: rsp:RSP_0367 preprotein translocase SecG subunit YP_917476.1 TIGRFAM: cobyric acid synthase CobQ; PFAM: Cobyrinic acid a,c-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: rsp:RSP_0796 cobyric acid synthase YP_917477.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_2453 oxidoreductase (NAD/NADP dependent) YP_917478.1 PFAM: protein of unknown function DUF1284; KEGG: wol:WD1205 hypothetical protein YP_917479.1 KEGG: sit:TM1040_1132 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase YP_917480.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_917481.1 PFAM: ComEC/Rec2-related protein; KEGG: sil:SPO2155 competence protein YP_917482.1 PFAM: Heme NO binding domain protein; KEGG: rsp:RSP_6114 hypothetical protein YP_917483.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rsp:RSP_0410 sensor diguanylate cyclase (GGDEF) YP_917484.1 KEGG: sit:TM1040_0587 conserved hypothetical protein YP_917487.1 PFAM: regulatory protein, LuxR; Bacterio-opsin activator, HTH domain protein; Sigma-70, region 4 type 2; KEGG: sit:TM1040_1212 transcriptional regulator, LuxR family YP_917488.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_917489.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_917491.1 PFAM: phage integrase family protein; KEGG: sit:TM1040_1692 phage integrase YP_917494.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: sty:HCM1.27c hypothetical protein YP_917500.1 KEGG: rde:RD1_2835 hypothetical protein YP_917501.1 KEGG: gox:GOX2477 hypothetical protein YP_917502.1 KEGG: par:Psyc_0982 probable phage-related protein YP_917512.1 KEGG: rsp:RSP_3792 hypothetical protein YP_917514.1 KEGG: sit:TM1040_0792 hypothetical protein YP_917515.1 KEGG: xfa:XF1666 hypothetical protein YP_917517.1 KEGG: ngo:NGO0494 hypothetical protein, phage associated protein YP_917518.1 TIGRFAM: phage terminase, large subunit, PBSX family; KEGG: zmo:ZMO0379 terminase YP_917520.1 KEGG: ppu:PP_1573 major tail protein YP_917521.1 KEGG: ppr:PBPRB0567 head-tail connector protein YP_917523.1 KEGG: ppr:PBPRB0569 endoprotease YP_917524.1 KEGG: ppr:PBPRB0570 hypothetical protein YP_917525.1 KEGG: ppr:PBPRB0571 hypothetical protein YP_917527.1 KEGG: pol:Bpro_3742 hypothetical protein YP_917528.1 KEGG: dde:Dde_2546 hypothetical protein YP_917529.1 KEGG: dvu:DVU1714 hypothetical protein YP_917530.1 KEGG: ppr:PBPRB_2036 hypothetical protein YP_917531.1 KEGG: sgl:SG1192 hypothetical protein YP_917532.1 KEGG: mlo:mlr2365 hypothetical protein YP_917533.1 KEGG: mag:amb3639 hypothetical protein YP_917535.1 KEGG: jan:Jann_1865 hypothetical protein YP_917536.1 PFAM: Arc domain protein DNA binding domain protein; KEGG: ypn:YPN_1596 phage regulatory protein YP_917537.1 KEGG: nha:Nham_2408 uncharacterized phage-encoded protein-like YP_917540.1 PFAM: metallophosphoesterase YP_917542.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sme:SMb20518 hypothetical protein YP_917546.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_917547.1 PFAM: dihydroorotate dehydrogenase; 2-nitropropane dioxygenase, NPD; KEGG: reu:Reut_B5128 2-nitropropane dioxygenase, NPD YP_917548.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_917549.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_917550.1 KEGG: sil:SPO0805 hypothetical protein YP_917551.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: sil:SPO0806 N-(5'-phosphoribosyl)anthranilate isomerase YP_917552.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_3586 aromatic pathway regulator YP_917553.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_917554.1 PFAM: DSBA oxidoreductase; KEGG: sil:SPOA0362 27kDa outer membrane protein YP_917555.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: bmb:BruAb2_0689 AlkB, alkylated DNA repair protein YP_917556.1 PFAM: protein of unknown function DUF861, cupin_3; Cupin 2, conserved barrel domain protein; KEGG: aor:AO090026000040 uncharacterized protein, possibly involved in glyoxylate utilization Pfam: Cupin_3 Cupin_2 AraC_binding Cupin_1 YP_917557.1 PFAM: polysaccharide deacetylase; KEGG: sil:SPO0872 polysaccharide deacetylase family protein YP_917558.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: bms:BRA0661 uracil-xanthine permease YP_917559.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sme:SMb20276 transcriptional regulator protein YP_917560.1 PFAM: aminotransferase class-III; KEGG: sme:SMb20277 hypothetical protein YP_917561.1 PFAM: MlrC domain protein; KEGG: rpd:RPD_1322 MlrC-like YP_917562.1 PFAM: extracellular solute-binding protein, family 5; KEGG: rpc:RPC_1200 extracellular solute-binding protein, family 5 YP_917563.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rpd:RPD_4024 binding-protein-dependent transport systems inner membrane component YP_917564.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rpc:RPC_1196 binding-protein-dependent transport systems inner membrane component YP_917565.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase; KEGG: bja:blr5600 ABC transporter ATP-binding protein YP_917566.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: bxe:Bxe_C1311 carbon-nitrogen hydrolase YP_917567.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: jan:Jann_2958 carboxymuconolactone decarboxylase YP_917568.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: sil:SPO1637 single-strand binding protein YP_917569.1 PFAM: Lytic transglycosylase, catalytic; KEGG: rsp:RSP_1794 lytic transglycosylase YP_917570.1 KEGG: rsp:RSP_2847 hypothetical protein YP_917571.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_917572.1 KEGG: rde:RD1_2747 hypothetical protein YP_917573.1 KEGG: rsp:RSP_2850 transcription-repair coupling factor (helicase); TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_917574.1 KEGG: rsp:RSP_2293 chaperonin ClpA/B; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_917575.1 PFAM: beta-lactamase domain protein; KEGG: sil:SPO3168 hydroxyacylglutathione hydrolase YP_917576.1 PFAM: Methyltransferase type 11; KEGG: rsp:RSP_2295 hypothetical protein YP_917577.1 TIGRFAM: ATP synthase F1, delta subunit; PFAM: H+-transporting two-sector ATPase, delta (OSCP) subunit; KEGG: rde:RD1_3536 ATP synthase F1, delta subunit YP_917578.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_917579.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_917580.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_917581.1 TIGRFAM: ATP synthase F1, epsilon subunit; PFAM: H+-transporting two-sector ATPase, delta/epsilon subunit; KEGG: sit:TM1040_2085 ATP synthase F1, epsilon subunit YP_917582.1 KEGG: sil:SPO3160 hypothetical protein YP_917583.1 PFAM: alpha/beta hydrolase fold; KEGG: sil:SPO3157 hydrolase, alpha/beta fold family YP_917584.1 PFAM: DSBA oxidoreductase; KEGG: sil:SPO3158 2-hydroxychromene-2-carboxylate isomerase YP_917585.1 KEGG: rsp:RSP_2301 phosphoribosyl pyrophosphate synthetase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_917586.1 PFAM: CoA-binding domain protein; KEGG: rsp:RSP_2240 hypothetical protein YP_917587.1 KEGG: sit:TM1040_2051 hypothetical protein YP_917588.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding; KEGG: rsp:RSP_2239 tRNA/rRNA metyltransferase YP_917592.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: xfa:XF2071 conserved hypothetical protein YP_917593.1 PFAM: plasmid stabilization system; KEGG: sme:SMb20063 hypothetical protein YP_917595.1 KEGG: mlo:mlr9349 hypothetical protein YP_917599.1 PFAM: helix-turn-helix domain protein; KEGG: nha:Nham_0800 transcriptional regulator, XRE family YP_917600.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: sal:Sala_2300 DNA methylase N-4/N-6 YP_917603.1 PFAM: helicase domain protein; SMART: DEAD-like helicases-like; KEGG: ppe:PEPE_0535 superfamily II DNA/RNA helicase, SNF2 family YP_917606.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_3955 transposase IS116/IS110/IS902 YP_917607.1 PFAM: transposase IS3/IS911 family protein; KEGG: nwi:Nwi_2119 transposase IS3/IS911 YP_917608.1 PFAM: Integrase, catalytic region; KEGG: nwi:Nwi_2120 integrase, catalytic region YP_917609.1 PFAM: helix-turn-helix domain protein YP_917611.1 PFAM: phage integrase family protein; KEGG: rsp:RSP_1968 possible integrase/recombinase YP_917618.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: rsp:RSP_3059 ABC proline/glycine betaine transporter, periplasmic substrate-binding protein YP_917619.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc02379 permease YP_917620.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_3057 ABC proline/glycine betaine transporter, ATPase subunit YP_917622.1 PFAM: NUDIX hydrolase; KEGG: rsp:RSP_2146 tellurite resistance protein YP_917623.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_917624.1 PFAM: MscS Mechanosensitive ion channel; KEGG: rsp:RSP_2148 small conductance mechanosensitive ion channel YP_917625.1 KEGG: atc:AGR_C_4132 hypothetical protein YP_917626.1 PFAM: protein of unknown function UPF0118; KEGG: rsp:RSP_3345 hypothetical protein YP_917627.1 negatively supercoils closed circular double-stranded DNA YP_917628.1 PFAM: Disulphide bond formation protein DsbB; KEGG: sil:SPO2117 disulfide bond formation protein, DsbB family YP_917629.1 KEGG: rpd:RPD_2135 DedA family protein YP_917630.1 PFAM: protein of unknown function, zinc metallopeptidase KEGG: sil:SPO3546 zinc metallopeptidase YP_917632.1 PFAM: cyclase/dehydrase; KEGG: rsp:RSP_2787 hypothetical protein YP_917633.1 KEGG: jan:Jann_1985 hypothetical protein YP_917634.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_917635.1 TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rsp:RSP_0960 alcohol dehydrogenase YP_917636.1 KEGG: fal:FRAAL4242 hypothetical protein YP_917637.1 KEGG: sil:SPO0368 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein YP_917638.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: sil:SPO3239 integral membrane protein YP_917639.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase; KEGG: rpe:RPE_2026 uncharacterized peroxidase-related enzyme YP_917640.1 KEGG: rsp:RSP_1053 signal recognition particle protein ffh; TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54, G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_917641.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_1051 hypothetical protein YP_917642.1 catalyzes the interconversion of chorismate to prephenate YP_917643.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_917644.1 Essential for efficient processing of 16S rRNA YP_917645.1 KEGG: rsp:RSP_1045 tRNA (guanine-N1-)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase YP_917646.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_917647.1 PFAM: ribosomal protein L31; KEGG: rde:RD1_1304 ribosomal protein L31 YP_917649.1 KEGG: rsp:RSP_1042 chromosome partitioning protein YP_917650.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rsp:RSP_2854 cation/multidrug efflux pump, membrane fusion protein (MFP) family YP_917651.1 PFAM: acriflavin resistance protein; KEGG: rpa:RPA4680 efflux transporter YP_917652.1 KEGG: rde:RD1_3014 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_917653.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase YP_917654.1 PFAM: dehydrogenase, E1 component; KEGG: sit:TM1040_1079 pyruvate dehydrogenase (lipoamide) YP_917655.1 PFAM: Septum formation initiator; KEGG: sit:TM1040_1081 septum formation initiator YP_917656.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_917657.1 KEGG: rde:RD1_0930 hypothetical protein YP_917658.1 PFAM: protein of unknown function DUF1523; KEGG: rsp:RSP_1760 hypothetical protein YP_917659.1 KEGG: rsp:RSP_3739 deoxyribose phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase YP_917660.1 PFAM: aldehyde dehydrogenase; KEGG: mes:Meso_0313 aldehyde dehydrogenase YP_917661.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sit:TM1040_2765 hydroxypyruvate isomerase YP_917662.1 PFAM: protein of unknown function DUF1285; KEGG: jan:Jann_0682 protein of unknown function DUF1285 YP_917663.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: rsp:RSP_1024 MoxR family protein YP_917664.1 KEGG: jan:Jann_0684 hypothetical protein YP_917665.1 TIGRFAM: conserved hypothetical membrane protein; KEGG: rsp:RSP_1022 conserved hypothetical protein (possibly transmembrane) YP_917666.1 KEGG: rde:RD1_0355 N-terminal double-transmembrane domain protein YP_917667.1 KEGG: rde:RD1_0356 hypothetical protein YP_917668.1 TIGRFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: rsp:RSP_2712 probable 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase YP_917669.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_917670.1 PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein YP_917671.1 KEGG: rsp:RSP_2716 lipid-A-disaccharide synthase; TIGRFAM: lipid-A-disaccharide synthase; PFAM: glycosyl transferase, family 19 YP_917672.1 PFAM: Endoribonuclease L-PSP; KEGG: bms:BRA1019 hypothetical protein YP_917673.1 PFAM: protein of unknown function DUF81; KEGG: ade:Adeh_2178 protein of unknown function DUF81 YP_917675.1 PFAM: NodS family protein; Methyltransferase type 11; Methyltransferase type 12; KEGG: bja:bll5506 hypothetical protein YP_917676.1 PFAM: protein of unknown function DUF989; KEGG: sil:SPO0869 hypothetical protein YP_917677.1 PFAM: Transthyretin; KEGG: rde:RD1_4150 hypothetical protein YP_917678.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway. YP_917679.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: sme:SMc02512 permease transmembrane protein YP_917680.1 PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: mes:Meso_4368 ornithine cyclodeaminase/mu-crystallin YP_917681.1 PFAM: alanine racemase domain protein; KEGG: mes:Meso_4367 alanine racemase-like YP_917682.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: sil:SPOA0145 pyridoxal-phosphate dependent enzyme YP_917683.1 PFAM: aminotransferase, class V; KEGG: mes:Meso_3308 aminotransferase, class V YP_917684.1 PFAM: regulatory protein, DeoR; regulatory proteins, IclR; KEGG: sil:SPOA0143 transcriptional regulator, IclR family YP_917686.1 PFAM: pentapeptide repeat protein; KEGG: cyb:CYB_1243 pentapeptide repeat family protein YP_917687.1 KEGG: jan:Jann_1578 transcriptional regulator, SARP family YP_917688.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_917689.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; KEGG: rsp:RSP_1970 phosphoribosylglycinamide formyltransferase YP_917690.1 PFAM: inner-membrane translocator; KEGG: sil:SPO1935 branched-chain amino acid ABC transporter, permease YP_917691.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_2926 ABC branched-chain amino acid transporter family, inner membrane subunit YP_917692.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2925 ABC branched-chain amino acid transporter family, ATPase subunit YP_917693.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rde:RD1_2630 branched-chain amino acid ABC transporter, ATP-binding protein YP_917694.1 PFAM: Extracellular ligand-binding receptor; KEGG: rsp:RSP_2923 ABC branched amino acid transporter family, periplasmic substrate-binding protein YP_917695.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: rsp:RSP_2922 transcriptional regulator, AraC family YP_917696.1 KEGG: rsp:RSP_2921 phospho-2-dehydro-3-deoxyheptonate; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II YP_917697.1 KEGG: rde:RD1_2636 hypothetical protein YP_917698.1 Essential for recycling GMP and indirectly, cGMP YP_917699.1 KEGG: jan:Jann_2439 transferase hexapeptide protein YP_917700.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: sil:SPO1947 phosphate regulon sensor histidine kinase YP_917701.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_917702.1 PFAM: Colicin V production protein; KEGG: rsp:RSP_2455 colicin V production protein, DedE YP_917703.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_917704.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; KEGG: rsp:RSP_1869 2-octaprenyl-6-methoxyphenyl hydroxylase YP_917705.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; pyrimidine 5'-nucleotidase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sil:SPO1374 pyrimidine 5'-nucleotidase YP_917706.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: rsp:RSP_1871 transcriptional regulator, GntR family YP_917707.1 PFAM: HhH-GPD family protein; KEGG: sil:SPO2127 DNA-3-methyladenine glycosylase II YP_917708.1 PFAM: dienelactone hydrolase; phospholipase/Carboxylesterase; KEGG: rsp:RSP_2728 phospholipase/carboxylesterase YP_917709.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mlo:mlr4624 lactoylglutathione lyase YP_917710.1 PFAM: small multidrug resistance protein; KEGG: pau:PA14_40170 transporter YP_917711.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: sil:SPO2123 HNH endonuclease family protein YP_917713.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sil:SPO2159 radical SAM domain protein YP_917714.1 catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine YP_917715.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_917716.1 PFAM: Rhomboid family protein; KEGG: sit:TM1040_0444 rhomboid-like protein YP_917717.1 TIGRFAM: integral membrane protein MviN; PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein; KEGG: rsp:RSP_1810 virulence factor, MviN YP_917718.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_917719.1 KEGG: rsp:RSP_1812 hypothetical protein YP_917720.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: rsp:RSP_1813 hypothetical protein YP_917721.1 PFAM: protein of unknown function UPF0102; KEGG: sil:SPO0400 endonuclease YP_917722.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_917723.1 KEGG: sil:SPO0402 competence protein ComM; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; SMART: AAA ATPase YP_917724.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_917725.1 PFAM: aminotransferase, class V; KEGG: rsp:RSP_0442 aminotransferase YP_917726.1 with SufCD activates cysteine desulfurase SufS YP_917727.1 PFAM: protein of unknown function DUF74; KEGG: rsp:RSP_0439 hypothetical protein YP_917728.1 KEGG: sil:SPO2018 FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase YP_917729.1 PFAM: SufBD protein; KEGG: rde:RD1_2692 FeS assembly protein SufD YP_917730.1 KEGG: rsp:RSP_0433 hypothetical protein YP_917731.1 KEGG: rsp:RSP_0432 hypothetical protein YP_917732.1 TIGRFAM: cysteine desulfurases, SufS subfamily; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sil:SPO2014 cysteine desulfurase SufS YP_917733.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_917734.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rsp:RSP_2950 transcriptional regulator, LysR family YP_917735.1 KEGG: rsp:RSP_2947 glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu racemase YP_917736.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_917737.1 PFAM: protein of unknown function DUF847; KEGG: rsp:RSP_2944 hypothetical protein YP_917738.1 KEGG: rsp:RSP_6081 hypothetical protein YP_917739.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: rsp:RSP_2633 cytochrome c maturation protein, CcmF YP_917740.1 PFAM: cytochrome C biogenesis protein; KEGG: sil:SPO1881 cytochrome c biogenesis family protein YP_917741.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: jan:Jann_2154 enoyl-CoA hydratase/isomerase YP_917742.1 PFAM: NUDIX hydrolase; KEGG: rsp:RSP_0419 hypothetical protein YP_917743.1 PFAM: protein of unknown function DUF983; KEGG: rsp:RSP_0418 hypothetical protein YP_917744.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: jan:Jann_3131 diguanylate cyclase YP_917745.1 KEGG: rru:Rru_A1259 hypothetical protein YP_917746.1 PFAM: aminotransferase class-III; KEGG: rsp:RSP_0379 aminotransferase YP_917747.1 PFAM: cytochrome P450; KEGG: sil:SPO1898 cytochrome P450 family protein YP_917748.1 KEGG: sil:SPO1897 hypothetical protein YP_917749.1 PFAM: peptidase M48, Ste24p; KEGG: jan:Jann_2687 peptidase M48, Ste24p YP_917750.1 PFAM: VWA containing CoxE family protein; KEGG: rsp:RSP_2650 hypothetical protein YP_917751.1 PFAM: Ppx/GppA phosphatase; KEGG: rsp:RSP_2771 exopolyphosphatase YP_917752.1 PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: rsp:RSP_2772 23S rRNA methylase YP_917753.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: jan:Jann_2462 transcriptional regulator, AraC family YP_917754.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_917755.1 Catalyzes the phosphorylation of UMP to UDP YP_917756.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_917757.1 KEGG: rsp:RSP_2707 UDP pyrophosphate synthase; TIGRFAM: UDP diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_917758.1 PFAM: phosphatidate cytidylyltransferase; KEGG: rsp:RSP_2708 phosphatidate cytidylyltransferase YP_917759.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_917760.1 TIGRFAM: membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: sil:SPO1668 membrane-associated zinc metalloprotease YP_917761.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: rsp:RSP_2711 outer membrane protein YP_917762.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: rde:RD1_2594 hypothetical protein YP_917763.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: rsp:RSP_2914 nucleoside hydrolase YP_917764.1 PFAM: peptidase S45, penicillin amidase; KEGG: rsp:RSP_2845 penicillin acylase (penicillin amidase) YP_917765.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: rsp:RSP_2846 3-hydroxyisobutyrate dehydrogenase YP_917766.1 PFAM: protein of unknown function DUF1130; KEGG: bbr:BB2477 hypothetical protein YP_917767.1 KEGG: nha:Nham_2097 hypothetical protein YP_917768.1 PFAM: major facilitator superfamily MFS_1; KEGG: atc:AGR_L_343 hypothetical protein YP_917769.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sit:TM1040_0406 periplasmic sensor signal transduction histidine kinase YP_917770.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: sit:TM1040_0405 two component, sigma54 specific, transcriptional regulator, fis family YP_917771.1 KEGG: sal:Sala_0186 oxidoreductase alpha (molybdopterin) subunit; TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_917772.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: nar:Saro_1025 cytochrome bd ubiquinol oxidase, subunit I YP_917773.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: nar:Saro_1026 cytochrome d ubiquinol oxidase, subunit II YP_917774.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_5668 ATPase AAA-2 domain protein YP_917775.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: bur:Bcep18194_C7011 multiple antibiotic resistance (MarC)-related proteins YP_917776.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: bam:Bamb_5665 Dyp-type peroxidase family YP_917777.1 PFAM: Linocin_M18 bacteriocin protein; KEGG: bbr:BB2479 bacteriocin YP_917778.1 PFAM: protein of unknown function UPF0187; KEGG: pen:PSEEN4044 hypothetical protein YP_917779.1 KEGG: rsp:RSP_0301 ABC branched chain amino acid transporter, substrate binding protein YP_917780.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_0300 ABC branched chain amino acid transporter, inner membrane subunit YP_917781.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_0299 ABC branched chain amino acid transporter, inner membrane subunit YP_917782.1 PFAM: ABC transporter related; KEGG: rsp:RSP_0298 ABC branched chain amino acid transporter, ATPase subunit YP_917783.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_0297 ABC branched chain amino acid transporter, ATPase subunit YP_917784.1 PFAM: Redoxin domain protein; KEGG: dar:Daro_3587 hypothetical protein YP_917785.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_917786.1 PFAM: protein of unknown function DUF442; KEGG: rsp:RSP_0167 hypothetical protein YP_917787.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: rsp:RSP_0448 EF-Tu; elongation factor Tu YP_917789.1 PFAM: ferredoxin; KEGG: sit:TM1040_1949 ferredoxin YP_917790.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_917791.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_917792.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_917793.1 KEGG: jan:Jann_0572 hypothetical protein YP_917794.1 functions in MreBCD complex in some organisms YP_917795.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_917796.1 KEGG: rsp:RSP_2327 rod shape-determining protein MreD YP_917797.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2326 cell division protein FtsI YP_917798.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: rsp:RSP_2325 RodA, rod cell shape determining protein YP_917799.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: jan:Jann_3650 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_917800.1 KEGG: sit:TM1040_3778 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II; Nucleotidyl transferase; Cupin 2, conserved barrel domain protein YP_917801.1 KEGG: rsp:RSP_0179 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components TauA YP_917802.1 PFAM: protein of unknown function DUF161; KEGG: rsp:RSP_0447 hypothetical protein YP_917803.1 PFAM: arsenate reductase and related; KEGG: rsp:RSP_0387 hypothetical protein YP_917804.1 KEGG: rsp:RSP_0238 hypothetical protein YP_917805.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rsp:RSP_1201 hypothetical protein YP_917806.1 PFAM: NnrS family protein; KEGG: sme:SMa1194 hypothetical protein YP_917807.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: atc:AGR_L_3461 probable transporter PA4289 YP_917809.1 PFAM: NAD(P) transhydrogenase, beta subunit; KEGG: sil:SPO2819 NAD(P)+ transhydrogenase, beta subunit YP_917810.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_917811.1 KEGG: jan:Jann_3303 protein of unknown function DUF1498 YP_917812.1 PFAM: Isoprenylcysteine carboxyl methyltransferase; KEGG: rsp:RSP_0241 protein-S-isoprenylcysteine methyltransferase YP_917813.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_917814.1 KEGG: jan:Jann_1769 mucin-associated surface protein YP_917815.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: rsp:RSP_1982 aminopeptidase N YP_917816.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: rsp:RSP_1983 phospholipid/glycerol acyltransferase YP_917817.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_917818.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_917819.1 PFAM: small multidrug resistance protein; KEGG: hch:HCH_07085 membrane transporters of cations and cationic drugs YP_917820.1 PFAM: protein of unknown function UPF0061; KEGG: sil:SPO2480 hypothetical protein YP_917821.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: bme:BMEII0240 dioxygenase YP_917822.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_917823.1 KEGG: sil:SPO2129 hypothetical protein YP_917824.1 TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: jan:Jann_1959 2-isopropylmalate synthase/homocitrate synthase YP_917825.1 KEGG: sit:TM1040_1153 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia YP_917826.1 KEGG: rsp:RSP_2721 hypothetical protein YP_917827.1 KEGG: gbe:GbCGDNIH1_2282 hypothetical secreted protein YP_917828.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_0015 ABC spermidine/putrescine transporter, ATPase subunit YP_917829.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0016 ABC spermidine/putrescine transporter, inner membrane subunit YP_917830.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0017 ABC spermidine/putrescine transporter, inner membrane subunit YP_917831.1 PFAM: protein of unknown function UPF0047; KEGG: rde:RD1_1797 hypothetical protein YP_917832.1 PFAM: protein of unknown function DUF195; KEGG: mmr:Mmar10_0441 protein of unknown function DUF195 YP_917833.1 PFAM: NADPH-dependent FMN reductase; KEGG: bte:BTH_II2367 NADPH-dependent FMN reductase domain protein YP_917834.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_917835.1 synthesizes RNA primers at the replication forks YP_917836.1 PFAM: regulatory protein, TetR; KEGG: sil:SPO1736 transcriptional regulator, TetR family YP_917837.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: rsp:RSP_0829 lactate dehydrogenase YP_917838.1 KEGG: pfl:PFL_4227 acyltransferase family protein YP_917839.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_917840.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_917841.1 PFAM: glutamyl-tRNA synthetase, class Ic; KEGG: rsp:RSP_2628 glutamyl-/glutaminyl-tRNA synthetase YP_917842.1 PFAM: phosphoribosyl-AMP cyclohydrolase; KEGG: rsp:RSP_2627 phosphoribosyl-AMP cyclohydrolase YP_917843.1 KEGG: rsp:RSP_2625 NifU-related protein involved in Fe-S cluster formation YP_917844.1 catalyzes branch migration in Holliday junction intermediates YP_917845.1 KEGG: sil:SPO1680 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: NAD-dependent DNA ligase-like YP_917846.1 KEGG: mmr:Mmar10_0669 two component transcriptional regulator, winged helix family YP_917849.1 PFAM: protein of unknown function DUF847; KEGG: bmb:BruAb1_0990 secretion activator protein, hypothetical YP_917851.1 PFAM: metallophosphoesterase; KEGG: nha:Nham_3850 complement C1q protein YP_917853.1 KEGG: sat:SYN_02283 hypothetical cytosolic protein YP_917854.1 KEGG: mlo:mll5675 hypothetical protein YP_917855.1 KEGG: jan:Jann_0236 hypothetical protein YP_917857.1 PFAM: phage integrase family protein; KEGG: mag:amb2709 integrase YP_917858.1 PFAM: response regulator receiver; KEGG: sil:SPO1679 DNA-binding response regulator CtrA YP_917859.1 PFAM: protein of unknown function DUF1153; KEGG: rsp:RSP_2620 hypothetical protein YP_917860.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_917861.1 PFAM: Fe-S metabolism associated SufE; KEGG: jan:Jann_1840 Fe-S metabolism associated SufE YP_917862.1 KEGG: rsp:RSP_1972 hypothetical protein YP_917863.1 PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_3821 acetyltransferase YP_917864.1 involved in the peptidyltransferase reaction during translation YP_917865.1 PFAM: ribosomal protein L21; KEGG: sil:SPO1990 ribosomal protein L21 YP_917866.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sco:SCO6730 racemase YP_917867.1 KEGG: sil:SPO2944 hypothetical protein YP_917868.1 KEGG: rha:RHA1_ro05532 nitrilotriacetate monooxygenase YP_917869.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mlo:mll9179 ABC transporter ATP-binding subunit YP_917870.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: nfa:nfa18270 transporter YP_917871.1 KEGG: nfa:nfa18260 sulfonate/nitrate transport system substrate-binding protein YP_917872.1 PFAM: HpcH/HpaI aldolase; KEGG: bmb:BruAb2_0163 hypothetical citrate lyase, beta subunit YP_917873.1 KEGG: bmb:BruAb2_0162 hypothetical protein YP_917874.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rpa:RPA1611 dehydratase YP_917875.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pfl:PFL_3598 glyoxalase family protein YP_917876.1 KEGG: rru:Rru_A2561 hypothetical protein YP_917877.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: mag:amb2135 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase YP_917878.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mag:amb3232 transcriptional regulator YP_917879.1 TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: bbr:BB4081 fumarate hydratase YP_917880.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rsp:RSP_0912 TRAP-T family C4-dicarboxylate transporter, DctM (12TMs) subunit YP_917881.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: rsp:RSP_0911 TRAP-T family C4-dicarboxylate transporter, DctQ (4TMs) subunit YP_917882.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rsp:RSP_0910 TRAP-T family transporter, C4-dicarboxylate-binding protein DctP YP_917883.1 TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; KEGG: rsp:RSP_2844 GTP-binding protein YP_917884.1 Stimulates the elongation of poly(A) tails YP_917885.1 PFAM: cation transporter; KEGG: rsp:RSP_2842 potassium uptake transporter, transmembrane subunit, TrkH YP_917886.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_917887.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: rsp:RSP_2840 nitrogen assimilation transcriptional regulator, NtrX YP_917888.1 KEGG: rsp:RSP_2839 nitrogen regulation protein, NtrY, signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_917889.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: rde:RD1_2763 nitrogen regulation protein YP_917890.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rsp:RSP_2837 nitrogen regulation protein, NtrB signal transduction histidine kinase YP_917891.1 TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS; KEGG: jan:Jann_2236 dihydrouridine synthase TIM-barrel protein nifR3 YP_917892.1 KEGG: rsp:RSP_0361 probable L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_917893.1 KEGG: cal:orf19.4334 hypothetical protein YP_917894.1 PFAM: protein of unknown function DUF940, membrane lipoprotein KEGG: rsp:RSP_1187 hypothetical protein YP_917895.1 KEGG: rsp:RSP_1186 hypothetical protein YP_917897.1 PFAM: ABC-3 protein; KEGG: rsp:RSP_3567 ABC zinc tranporter, inner membrane subunit ZnuB YP_917898.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_3568 ABC zinc transporter, ATPase subunit ZnuC YP_917899.1 KEGG: rsp:RSP_3569 zinc-uptake regulator, Zur YP_917900.1 PFAM: periplasmic solute binding protein; KEGG: rsp:RSP_3571 ABC zinc transporter, periplasmic binding protein ZnuA YP_917901.1 KEGG: sil:SPO0789 hypothetical protein YP_917902.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: rsp:RSP_2266 pseudouridine synthase, (predicted) YP_917903.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rde:RD1_1993 cytidine and deoxycytidylate deaminase family protein YP_917904.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_917905.1 PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: sil:SPO0988 YeeE/YedE family protein YP_917906.1 PFAM: regulatory protein, ArsR; KEGG: rsp:RSP_2606 ArsR family arsenical resistance operon repressor YP_917907.1 KEGG: rde:RD1_1508 SoxS YP_917908.1 PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: sil:SPO0991 sulfur oxidation V protein YP_917909.1 KEGG: sil:SPO0992 thioredoxin SoxW YP_917910.1 PFAM: cytochrome c, class I; KEGG: sil:SPO0993 monoheme cytochrome c SoxX YP_917911.1 with SoxZ catalyzes the oxidation of sulfur compounds YP_917912.1 KEGG: rde:RD1_1513 sulfur oxidation Z protein YP_917913.1 KEGG: sil:SPO0996 diheme cytochrome c SoxA YP_917914.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sil:SPO0997 sulfur oxidation B protein YP_917915.1 PFAM: oxidoreductase, molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: rde:RD1_1516 sulfite dehydrogenase SoxC protein YP_917916.1 PFAM: cytochrome c, class I; KEGG: sil:SPO0999 diheme cytochrome c SoxD YP_917917.1 PFAM: cytochrome c, class I; KEGG: rde:RD1_1518 cytochrome c2 YP_917918.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sil:SPO1001 sulfur oxidation F protein YP_917919.1 PFAM: beta-lactamase domain protein; KEGG: sil:SPO0788 metallo-beta-lactamase family protein YP_917920.1 KEGG: sil:SPO2822 SoxH protein, homolog YP_917921.1 PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: sil:SPO3123 YeeE/YedE family protein YP_917922.1 KEGG: ana:all1980 unknown protein YP_917923.1 KEGG: sit:TM1040_2280 hypothetical protein YP_917924.1 PFAM: helix-turn-helix, HxlR type; KEGG: bja:bll5105 transcriptional regulatory protein YP_917925.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: bja:blr5106 acyl-carrier-protein phosphodiesterase YP_917926.1 PFAM: NnrS family protein; KEGG: atc:AGR_L_924 hypothetical protein YP_917927.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_L_926 probable ATP-binding component of ABC taurine transporter YP_917928.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_927 ABC transporter, permease, cysTW family YP_917929.1 KEGG: atc:AGR_L_928 sulfonate/nitrate transport system substrate-binding protein YP_917930.1 KEGG: nha:Nham_2539 hypothetical protein YP_917931.1 KEGG: net:Neut_2232 conserved hypothetical protein YP_917932.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: nha:Nham_3286 transcriptional regulator, BadM/Rrf2 family YP_917933.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rpd:RPD_3065 TonB-dependent receptor YP_917934.1 PFAM: sugar-binding domain protein; KEGG: mes:Meso_3776 transcriptional regulator, DeoR family YP_917935.1 PFAM: carbohydrate kinase, FGGY; KEGG: mes:Meso_3784 FGGY-family pentulose kinase YP_917936.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: atc:AGR_L_828 hypothetical protein YP_917937.1 PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain; KEGG: mlo:mll4920 mannitol dehydrogenase YP_917938.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sit:TM1040_0428 ABC transporter related YP_917939.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01498 probable sorbitol/mannitol transport inner membrane protein YP_917940.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMc01497 probable sorbitol/mannitol transport inner membrane transmembrane protein YP_917941.1 PFAM: extracellular solute-binding protein, family 1; KEGG: sme:SMc01496 probable sorbitol-binding periplasmic protein YP_917942.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_917943.1 PFAM: Radical SAM domain protein; KEGG: sit:TM1040_2045 radical SAM YP_917944.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: sit:TM1040_2046 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_917945.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: sit:TM1040_2047 ExsB YP_917946.1 KEGG: mes:Meso_1301 hypothetical protein YP_917947.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_917948.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_3288 ABC glycerol-3-phosphate transporter, inner membrane subunit UgpE YP_917949.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_3289 ABC glycerol-3-phosphate transporter, inner membrane subunit UgpA YP_917950.1 PFAM: extracellular solute-binding protein, family 1; KEGG: rsp:RSP_3290 ABC glycerol-3-phosphate transporter, periplasmic binding protein, UgpB YP_917952.1 KEGG: gvi:glr3599 hypothetical protein YP_917954.1 PFAM: transcriptional activator domain; Tetratricopeptide TPR_2 repeat protein; KEGG: mlo:mlr7075 similar to trifolitoxin synthesis, TfuA YP_917955.1 PFAM: nitroreductase; KEGG: tko:TK0839 NAD(P)H-flavin oxidoreductase YP_917956.1 TIGRFAM: uncharacterized domain; PFAM: protein of unknown function DUF181; KEGG: bcn:Bcen_5136 protein of unknown function DUF181 YP_917957.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ccr:CC3726 molybdopterin biosynthesis protein MoeB YP_917958.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sus:Acid_0877 radical SAM domain protein YP_917960.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_3081 ABC multidrug efflux transporter, fused ATPase and inner membrane subunits YP_917961.1 TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: jan:Jann_2132 TonB-dependent haem/haemoglobin receptor YP_917962.1 PFAM: Haemin-degrading family protein; KEGG: jan:Jann_2133 haemin-degrading YP_917963.1 PFAM: periplasmic binding protein; KEGG: rde:RD1_4189 hemin ABC transporter, periplasmic hemin-binding protein YP_917964.1 PFAM: transport system permease; KEGG: jan:Jann_2135 transport system permease YP_917965.1 with HmuTU is involved in the transport of hemin YP_917966.1 PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: bja:blr6070 alcohol dehydrogenase YP_917967.1 PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: bxe:Bxe_B0358 poly-beta-hydroxyalkanoate synthasePhbC YP_917968.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: lpn:lpg2262 acetate kinase YP_917969.1 PFAM: phosphate acetyl/butaryl transferase; KEGG: lpp:lpp2215 phosphate acetyltransferase YP_917970.1 PFAM: response regulator receiver; KEGG: rsp:RSP_0573 response regulator receiver protein YP_917971.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_917972.1 PFAM: protein of unknown function DUF485; KEGG: rsp:RSP_3141 hypothetical protein YP_917973.1 TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: rsp:RSP_0579 acetyl-coenzyme A synthetase YP_917974.1 PFAM: ApbE family lipoprotein; KEGG: rpc:RPC_0433 twin-arginine translocation pathway signal YP_917975.1 PFAM: NosL family protein; KEGG: sil:SPOA0054 nitrous oxide reductase accessory protein YP_917976.1 KEGG: sil:SPOA0053 nitrous oxide maturation protein NosY YP_917977.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sil:SPOA0052 ABC transporter, ATP-binding protein NosF YP_917978.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: sil:SPOA0051 nitrous oxide maturation protein NosD YP_917979.1 reduces nitrous oxide to nitrogen YP_917980.1 PFAM: FMN-binding domain protein; KEGG: sil:SPOA0049 nitrous-oxide reductase transcriptional activator NosR YP_917982.1 TIGRFAM: pseudoazurin; PFAM: blue (type 1) copper domain protein; KEGG: sme:SMa1243 Azu1 pseudoazurin (blue copper protein) YP_917983.1 KEGG: rde:RD1_1693 hypothetical protein YP_917984.1 PFAM: protein of unknown function DUF542, ScdA domain protein; Hemerythrin HHE cation binding domain protein; KEGG: sme:SMa1195 hypothetical protein YP_917985.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: rsp:RSP_0468 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_917986.1 TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: rsp:RSP_0467 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_917987.1 KEGG: rsp:RSP_0466 hypothetical protein YP_917988.1 PFAM: peptidase U32; KEGG: rsp:RSP_0465 protease YP_917989.1 PFAM: peptidase U32; KEGG: rsp:RSP_0464 protease YP_917990.1 PFAM: NnrS family protein; KEGG: rde:RD1_1694 NnrS protein YP_917991.1 KEGG: sil:SPO1135 hypothetical protein YP_917992.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: rde:RD1_2446 peptidyl-prolyl cis-trans isomerase YP_917993.1 TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase, gamma subunit; KEGG: mmr:Mmar10_2703 respiratory nitrate reductase, gamma subunit YP_917994.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase, delta subunit; KEGG: rde:RD1_2444 nitrate reductase, delta subunit YP_917995.1 TIGRFAM: nitrate reductase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: rde:RD1_2443 nitrate reductase, beta subunit YP_917996.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: rde:RD1_2442 nitrate reductase, alpha subunit YP_917997.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: bms:BRA0300 nitrite extrusion protein YP_917998.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism YP_917999.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase; Ada, metal-binding domain protein; KEGG: rso:RSc2570 probable ADA regulatory of adaptative response contains: methylated-DNA--protein-cysteine methyltransferaseO-6-methylguanine-DNA transcription regulator YP_918000.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: mes:Meso_0336 siderophore-interacting protein YP_918001.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: rpc:RPC_4760 drug resistance transporter Bcr/CflA subfamily YP_918002.1 KEGG: atc:AGR_L_2076 hypothetical protein YP_918003.1 PFAM: GntR domain protein; KEGG: atc:AGR_L_2076 hypothetical protein YP_918004.1 PFAM: Asparaginase/glutaminase; KEGG: atc:AGR_L_2084 L-asparaginase YP_918005.1 PFAM: oxidoreductase domain protein; KEGG: mes:Meso_0843 oxidoreductase-like YP_918006.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_918007.1 PFAM: protein of unknown function DUF1238; KEGG: mlo:mll5655 hypothetical protein YP_918008.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mes:Meso_0837 transcriptional regulator, LysR family YP_918009.1 PFAM: sodium:dicarboxylate symporter; KEGG: yps:YPTB2365 DAACS family Na/dicarboxylate symporter YP_918010.1 PFAM: Ankyrin; KEGG: bur:Bcep18194_B0071 ankyrin repeat protein YP_918011.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: rme:Rmet_3722 CMP/dCMP deaminase, zinc-binding YP_918012.1 PFAM: major facilitator superfamily MFS_1; KEGG: reu:Reut_B5382 major facilitator superfamily MFS_1 YP_918013.1 PFAM: protein of unknown function DUF336; KEGG: cps:CPS_4893 GlcG protein YP_918014.1 PFAM: protein of unknown function DUF81; KEGG: rpa:RPA0111 DUF81 YP_918015.1 KEGG: rsp:RSP_3200 molecular chaperone, DnaK YP_918016.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sit:TM1040_2703 transcriptional regulator, LysR family YP_918017.1 PFAM: ferredoxin; molybdopterin dehydrogenase, FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein; KEGG: sit:TM1040_2704 molybdopterin dehydrogenase, FAD-binding YP_918018.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: sit:TM1040_2705 xanthine dehydrogenase YP_918019.1 PFAM: protein of unknown function DUF182; KEGG: mlo:mlr5136 xanthine dehydrogenase accessory factor YP_918020.1 Catalyzes the deamination of guanine YP_918021.1 KEGG: rpc:RPC_3603 acetone carboxylase gamma subunit YP_918022.1 PFAM: Hydantoinase B/oxoprolinase; KEGG: rpc:RPC_3604 hydantoinase B/oxoprolinase YP_918023.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: rpc:RPC_3605 hydantoinase/oxoprolinase YP_918024.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: rpc:RPC_3606 sigma54 specific transcriptional regulator with GAF sensor, fis family YP_918025.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: pfl:PFL_3673 transcriptional regulator, GntR family YP_918026.1 PFAM: Uncharacterized conserved protein UCP012702; MlrC domain protein; KEGG: bam:Bamb_6097 MlrC domain protein YP_918027.1 KEGG: sil:SPO1781 amidase, hydantoinase/carbamoylase family; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20; peptidase dimerisation domain protein YP_918028.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rme:Rmet_4479 ABC transporter related YP_918029.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rme:Rmet_4478 ABC transporter related YP_918030.1 PFAM: inner-membrane translocator; KEGG: bxe:Bxe_B2564 ABC branched chain amino acid family transporter, inner membrane subunit YP_918031.1 PFAM: inner-membrane translocator; KEGG: rme:Rmet_4476 inner-membrane translocator YP_918032.1 KEGG: rme:Rmet_4475 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein YP_918033.1 PFAM: aminotransferase class-III; KEGG: rsp:RSP_0943 probable adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_918034.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: rde:RD1_0978 transcriptional regulator, GntR family YP_918035.1 KEGG: rsp:RSP_4009 phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase YP_918036.1 PFAM: conserved hypothetical protein 698; KEGG: rsp:RSP_4010 conserved hypothetical protein 698 YP_918037.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_918038.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase; KEGG: sil:SPO2359 oxidoreductase, GMC family YP_918039.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bxe:Bxe_B0699 major facilitator superfamily (MFS)metabolite/H+ symporter YP_918040.1 PFAM: regulatory proteins, IclR; KEGG: sil:SPO2355 transcriptional regulator, IclR family YP_918041.1 KEGG: sil:SPO0664 peptide ABC transporter, ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_918042.1 KEGG: sth:STH2824 oligopeptide ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_918043.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rpa:RPA0100 ABC transporter permease YP_918044.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sil:SPO0661 peptide ABC transporter, permease YP_918045.1 PFAM: extracellular solute-binding protein, family 5; KEGG: rpa:RPA0102 ABC transporter oligopeptide-binding protein YP_918046.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sil:SPO0659 transcriptional regulator, LysR family YP_918047.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: jan:Jann_3250 amidohydrolase 3 YP_918048.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: jan:Jann_3251 cobalamin synthesis protein, P47K YP_918049.1 KEGG: jan:Jann_1560 hypothetical protein YP_918050.1 KEGG: jan:Jann_1559 hypothetical protein YP_918051.1 KEGG: jan:Jann_1558 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein YP_918052.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_918053.1 PFAM: helix-turn-helix, HxlR type; KEGG: ccr:CC3368 hypothetical protein YP_918054.1 PFAM: 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: stm:STM4401 reductase YP_918055.1 PFAM: UvrD/REP helicase; KEGG: rsp:RSP_2092 UvrD/DNA helicase II YP_918057.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_918058.1 TIGRFAM: O-succinylhomoserine sulfhydrylase; PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; KEGG: rsp:RSP_1851 O-succinylhomoserine sulfhydrylase YP_918059.1 PFAM: Intracellular septation protein A; KEGG: rsp:RSP_1841 probable intracellular septation protein YP_918060.1 PFAM: protein of unknown function DUF1223; KEGG: sil:SPO2311 hypothetical protein YP_918061.1 Catalyzes the conversion of citrate to isocitrate YP_918062.1 KEGG: rsp:RSP_0681 hypothetical protein YP_918063.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_918064.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: rde:RD1_2960 HesB-like iron-sulfur cluster assembly protein YP_918065.1 PFAM: triosephosphate isomerase; KEGG: rsp:RSP_1947 triosephosphate isomerase YP_918066.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_0129 ABC D-methionine uptake transporter, ATPase subunit YP_918067.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0130 ABC D-methionine uptake transporter, inner membrane subunit YP_918068.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: rsp:RSP_0132 ABC D-methionine uptake transporter, substrate-binding protein YP_918069.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: rsp:RSP_0029 acetyl-CoA hydrolase/transferase family protein YP_918070.1 PFAM: DoxX family protein; KEGG: bja:bll6552 hypothetical protein YP_918071.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rru:Rru_A1041 transcriptional regulator, LysR family YP_918072.1 PFAM: FAD linked oxidase domain protein; KEGG: rsp:RSP_1835 FAD dependent oxidoreductase YP_918073.1 PFAM: GCN5-related N-acetyltransferase; KEGG: jan:Jann_3147 GCN5-related N-acetyltransferase YP_918074.1 PFAM: peptidase M16 domain protein; KEGG: rsp:RSP_1832 peptidase, M16 family YP_918075.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_918076.1 KEGG: rsp:RSP_1830 SURF1 protein YP_918077.1 PFAM: cytochrome c oxidase, subunit III; KEGG: rsp:RSP_1829 cytochrome c oxidase, aa3-type, subunit III YP_918078.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_918079.1 KEGG: jan:Jann_3153 hypothetical protein YP_918080.1 converts protoheme IX and farnesyl diphosphate to heme O YP_918081.1 PFAM: cytochrome c oxidase, subunit II; cytochrome C oxidase subunit II, transmembrane region; KEGG: sil:SPO3076 cytochrome c oxidase, subunit II YP_918082.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: rsp:RSP_1825 probable modulator of DNA gyrase YP_918083.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: jan:Jann_3158 DNA processing protein DprA YP_918084.1 PFAM: OmpA/MotB domain protein; KEGG: rsp:RSP_1933 outer membrane protein, OmpA/MotB family YP_918085.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sil:SPO1953 phosphate regulon transcriptional regulatory protein PhoB YP_918086.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; KEGG: rsp:RSP_2600 phosphate transport system regulatory protein YP_918087.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_918088.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_2602 ABC phosphate transporter, inner membrane subunit PstA YP_918089.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_2290 phosphate ABC transporter, permease PstC YP_918090.1 KEGG: sit:TM1040_1262 phosphate ABC transporter, periplasmic phosphate-binding protein YP_918092.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_918094.1 PFAM: amino acid permease-associated region; KEGG: rha:RHA1_ro06596 cationic amino acid transporter, APC family YP_918095.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: mes:Meso_2600 type I secretion membrane fusion protein, HlyD family YP_918096.1 KEGG: mes:Meso_2599 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase YP_918097.1 KEGG: mes:Meso_2598 hypothetical protein YP_918098.1 KEGG: mes:Meso_2597 PE-PGRS family protein YP_918099.1 PFAM: regulatory protein, LuxR; KEGG: dra:DRB0081 DNA-binding response regulator YP_918100.1 KEGG: mes:Meso_2596 hypothetical protein YP_918101.1 KEGG: rru:Rru_A3403 sulphate transport system permease 1; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_918102.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb21131 sulfate uptake ABC transporter permease YP_918103.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rru:Rru_A3401 sulfate ABC transporter, permease CysT YP_918104.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: sme:SMb21133 sulfate uptake ABC transporter periplasmic solute-binding protein precursor, similar to Y11244 YP_918105.1 PFAM: secretion protein HlyD family protein; KEGG: pae:PA4142 probable secretion protein YP_918106.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; peptidase C39, bacteriocin processing; SMART: AAA ATPase; KEGG: bpm:BURPS1710b_3626 colicin V processing peptidase YP_918107.1 PFAM: Radical SAM domain protein; KEGG: sma:SAV5715 hypothetical protein YP_918108.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: pau:PA14_46370 two-component sensor YP_918109.1 PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein; Sigma-70, region 4 type 2; KEGG: pfo:Pfl_3254 two component transcriptional regulator, LuxR family YP_918110.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_918111.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin; KEGG: rsp:RSP_3174 nucleoside transporter, NCS1 family YP_918112.1 PFAM: Hydantoinase B/oxoprolinase; KEGG: hwa:HQ2241A N-methylhydantoinase B (ATP-hydrolyzing) YP_918113.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: hwa:HQ2242A N-methylhydantoinase A (ATP-hydrolyzing) YP_918114.1 PFAM: isochorismatase hydrolase; KEGG: rha:RHA1_ro10206 phthalate ester hydrolase (isochorismatase hydrolase) YP_918115.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: jan:Jann_3249 transcriptional regulator, LysR family YP_918116.1 PFAM: cytochrome B561; KEGG: jan:Jann_0302 cytochrome b561 YP_918117.1 KEGG: jan:Jann_0303 CDP-alcohol phosphatidyltransferase YP_918118.1 PFAM: sulfatase; KEGG: jan:Jann_0304 hypothetical protein YP_918119.1 KEGG: jan:Jann_0306 twin-arginine translocation pathway signal YP_918120.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: jan:Jann_0307 ABC transporter related YP_918121.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: jan:Jann_0308 binding-protein-dependent transport systems inner membrane component YP_918122.1 PFAM: glycosyl transferase, group 1; KEGG: jan:Jann_0309 glycosyl transferase, group 1 YP_918123.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: sme:SMc04173 hypothetical protein YP_918124.1 PFAM: ThiJ/PfpI domain protein; KEGG: bbr:BB2338 probable transcriptional regulator YP_918125.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: mmr:Mmar10_1581 transcriptional regulator, AraC family YP_918126.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_1485 ATP-dependent RNA helicase YP_918127.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sme:SMb20683 transcriptional regulator, LysR family protein YP_918128.1 involved in the transport of C4-dicarboxylates across the membrane YP_918129.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rpe:RPE_1784 transcriptional regulator, LysR family YP_918130.1 PFAM: conserved hypothetical protein 698; KEGG: rpe:RPE_1785 conserved hypothetical protein 698 YP_918131.1 KEGG: rsp:RSP_0408 hypothetical protein YP_918132.1 KEGG: mlo:mll4732 glycolate oxidase, (S)-2-hydroxy-acid oxidase, peroxisomal YP_918133.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_0697 TonB-dependent siderophore receptor YP_918135.1 TIGRFAM: Glutaredoxin-like protein NrdH; PFAM: glutaredoxin; KEGG: sit:TM1040_0521 glutaredoxin-like protein NrdH YP_918136.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_918137.1 Catalyzes the rate-limiting step in dNTP synthesis YP_918138.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_918139.1 PFAM: Bile acid:sodium symporter; KEGG: mes:Meso_2484 bile acid:sodium symporter YP_918140.1 PFAM: aminotransferase, class I and II; KEGG: xcv:XCV1904 aminotransferase YP_918141.1 PFAM: Citrate transporter; TrkA-C domain protein; KEGG: sme:SMa1916 hypothetical protein YP_918142.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rru:Rru_A0488 TonB-dependent receptor YP_918143.1 PFAM: periplasmic binding protein; KEGG: rsp:RSP_2403 ABC cobalamin/Fe3+-siderophore transporter, periplasmic substrate-binding subunit YP_918144.1 PFAM: transport system permease; KEGG: rsp:RSP_2404 ABC cobalamin/Fe3+-siderophore transporter, inner membrane subunit YP_918145.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2405 ABC cobalamin/Fe3+-siderophore transporter, ATPase subunit YP_918146.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; KEGG: rsp:RSP_2662 glycerol kinase YP_918147.1 KEGG: rsp:RSP_2663 ABC sugar (glycerol) transporter, periplasmic binding protein YP_918148.1 KEGG: rsp:RSP_2664 hypothetical protein YP_918149.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_2665 ABC sugar (glycerol) transporter, inner membrane subunit YP_918150.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_2666 ABC sugar (glycerol) transporter, inner membrane subunit YP_918151.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2667 ABC sugar (glycerol) transporter, ATPase subunit YP_918152.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_2669 ABC sugar (glycerol) transporter, ATPase subunit YP_918153.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_918155.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_918156.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis YP_918157.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: sil:SPO3480 glycolate oxidase, iron-sulfur subunit YP_918158.1 PFAM: FAD linked oxidase domain protein; KEGG: sit:TM1040_2501 FAD linked oxidase-like YP_918159.1 PFAM: FAD linked oxidase domain protein; KEGG: rsp:RSP_1020 glycolate oxidase subunit protein YP_918160.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein; KEGG: rru:Rru_A1414 regulatory protein GntR YP_918161.1 PFAM: Uncharacterized protein UPF0065; KEGG: sme:SMa1927 hypothetical protein YP_918162.1 PFAM: protein of unknown function DUF112, transmembrane; KEGG: atc:AGR_C_184 hypothetical protein YP_918163.1 PFAM: protein of unknown function DUF1468; KEGG: sme:SMb20026 hypothetical protein YP_918164.1 PFAM: Uncharacterized protein UPF0065; KEGG: sme:SMb20025 hypothetical protein YP_918165.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: ret:RHE_CH03433 probable two-component response regulator protein YP_918166.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: ret:RHE_CH03434 probable two-component sensor histidine kinase YP_918167.1 KEGG: bur:Bcep18194_A6285 permease for cytosine/purines, uracil, thiamine, allantoin tranporter YP_918168.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: ppu:PP_3515 hydantoin utilization protein A YP_918169.1 PFAM: Hydantoinase B/oxoprolinase; KEGG: pfl:PFL_2733 hydantoin utilization protein B YP_918170.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: ppu:PP_3516 transcriptional regulator, AraC family YP_918171.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sil:SPO0820 CaiB/BaiF family protein YP_918172.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: mlo:mll2878 glutaryl Co-A dehydrogenase YP_918173.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mes:Meso_2482 transcriptional regulator, LysR family YP_918174.1 TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: jan:Jann_3070 4-aminobutyrate aminotransferase YP_918175.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: rde:RD1_0838 transcription regulator YP_918176.1 PFAM: aldehyde dehydrogenase; KEGG: atc:AGR_L_2660 hypothetical protein YP_918177.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_918178.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: rde:RD1_3141 integral membrane protein YP_918179.1 KEGG: rsp:RSP_2018 hypothetical protein YP_918180.1 PFAM: Silent information regulator protein Sir2; KEGG: rde:RD1_1683 NAD-dependent deacetylase YP_918181.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sil:SPO0476 alkylphosphonate utilization protein PhnM YP_918182.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: sil:SPO0640 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein YP_918183.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_918184.1 KEGG: rde:RD1_2871 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_918185.1 KEGG: jan:Jann_3116 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_918186.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_918187.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_918188.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_918189.1 KEGG: rsp:RSP_2887 glycogen phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases; PFAM: glycosyl transferase, family 35 YP_918190.1 KEGG: sil:SPO3245 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_918191.1 catalyzes the formation of oxaloacetate from L-aspartate YP_918192.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_918193.1 PFAM: regulatory proteins, IclR; KEGG: sil:SPO2355 transcriptional regulator, IclR family YP_918194.1 KEGG: rsp:RSP_0816 aminotransferase, class IV YP_918195.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_918196.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: rsp:RSP_1245 predicted oxidoreductase, Gfo/Idh/MocA family YP_918197.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: sme:SMb20330 probable trehalosemaltose utilization protein, function YP_918198.1 PFAM: protein of unknown function DUF1037; KEGG: atc:AGR_L_2958 probable ThuA protein, function YP_918199.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ret:RHE_PF00207 trehalosemaltose ABC transporter, ATP-binding protein YP_918200.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bms:BRA0306 sugar ABC transporter, permease YP_918201.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20326 probable trehalosemaltose transporter permease YP_918202.1 PFAM: extracellular solute-binding protein, family 1; KEGG: sme:SMb20325 probable trehalosemaltose-binding protein YP_918203.1 PFAM: electron transport protein SCO1/SenC; KEGG: mes:Meso_1992 electron transport protein SCO1/SenC YP_918204.1 PFAM: protein of unknown function DUF461; nuclear export factor GLE1; KEGG: sme:SMc01242 signal peptide protein YP_918206.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_C_717 hypothetical protein YP_918207.1 PFAM: extracellular solute-binding protein, family 1; KEGG: atc:AGR_C_715 iron binding protein YP_918208.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_2539 ABC transporter, ATPase subunit YP_918209.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: jan:Jann_3045 molybdopterin oxidoreductase YP_918210.1 PFAM: formate/nitrite transporter; KEGG: bcn:Bcen_5755 formate/nitrite transporter YP_918211.1 TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: rde:RD1_4167 assimilatory nitrite reductase, small subunit YP_918212.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: rde:RD1_4168 assimilatory nitrite reductase, large subunit YP_918213.1 PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMb20436 nitrate transporter protein YP_918214.1 KEGG: jan:Jann_3039 nitrate transport protein YP_918215.1 PFAM: ANTAR domain protein; KEGG: jan:Jann_3038 response regulator receiver (CheY-like) and ANTAR domain protein YP_918216.1 PFAM: 3-alpha; MOSC domain containing protein; KEGG: rsp:RSP_1921 MOSC domain protein YP_918217.1 TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: rsp:RSP_1920 pyridoxal/pyridoxine/pyridoxamine kinase YP_918218.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; KEGG: sil:SPOA0306 S1 RNA binding domain protein YP_918220.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein; KEGG: sit:TM1040_1024 YjeF-related protein-like YP_918221.1 PFAM: nitrogen regulatory protein P-II; KEGG: rsp:RSP_0146 nitrogen regulatory protein P-II YP_918222.1 KEGG: rsp:RSP_0147 glutamine synthetase class-I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp YP_918223.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_918224.1 PFAM: flagellar motor switch protein FliG; KEGG: rsp:RSP_2220 possible flagellar motor switch protein (FliG) YP_918225.1 KEGG: rsp:RSP_2959 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_918226.1 KEGG: rsp:RSP_0307 antifreeze protein, type I YP_918227.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_918228.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_918229.1 unwinds double stranded DNA YP_918230.1 PFAM: protein of unknown function DUF486; KEGG: rsp:RSP_2188 hypothetical protein YP_918231.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: rsp:RSP_2187 multidrug efflux pump, major facilitator superfamily (MFS) YP_918232.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; KEGG: rsp:RSP_2186 transcriptional regulator, MerR family YP_918233.1 PFAM: peptidase M23B; KEGG: rde:RD1_3002 peptidase, M23/M37 family YP_918234.1 PFAM: protein of unknown function DUF583; KEGG: rsp:RSP_2975 hypothetical protein YP_918235.1 KEGG: rsp:RSP_2976 hypothetical protein YP_918236.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_918237.1 PFAM: CBS domain containing protein; KEGG: rsp:RSP_2961 protein containing a CBS domain YP_918238.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rsp:RSP_2965 transcriptional regulator, LysR family YP_918239.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sit:TM1040_1106 methylmalonate-semialdehyde dehydrogenase YP_918240.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: rsp:RSP_0156 acyl-CoA dehydrogenase YP_918241.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sil:SPO2212 enoyl-CoA hydratase/isomerase family protein YP_918242.1 TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: rsp:RSP_0154 3-hydroxyisobutyrate dehydrogenase YP_918244.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: rsp:RSP_2118 DNA repair protein RecN YP_918245.1 KEGG: rsp:RSP_2117 ComL lipoprotein YP_918246.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_918247.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_918248.1 PFAM: cell division protein FtsA; KEGG: rsp:RSP_2113 cell division protein FtsA YP_918249.1 PFAM: cell division protein FtsQ; KEGG: rsp:RSP_2112 cell division septal protein FtsQ YP_918250.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_918251.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_918253.1 KEGG: jan:Jann_2756 hypothetical protein YP_918254.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_918255.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_918256.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rsp:RSP_2106 cell division protein FtsW YP_918257.1 PFAM: DoxX family protein; KEGG: ret:RHE_CH00824 hypothetical conserved membrane protein YP_918258.1 KEGG: rsp:RSP_0009 hypothetical protein YP_918259.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_918260.1 PFAM: protein of unknown function DUF344; KEGG: rsp:RSP_0013 hypothetical protein YP_918261.1 PFAM: protein of unknown function DUF477; KEGG: sil:SPO2950 hypothetical protein YP_918262.1 KEGG: rsp:RSP_2141 ABC polyamine transporter, periplasmic substrate-binding protein YP_918263.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_918264.1 KEGG: rsp:RSP_3825 hypothetical protein YP_918265.1 KEGG: rsp:RSP_6239 hypothetical protein YP_918266.1 KEGG: rsp:RSP_3826 hypothetical protein YP_918267.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: rde:RD1_2655 acyltransferase YP_918268.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: jan:Jann_3383 TrkA-like YP_918269.1 KEGG: rde:RD1_2012 hypothetical protein YP_918270.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: jan:Jann_4208 2-polyprenylphenol 6-hydroxylase YP_918271.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: rsp:RSP_1338 methyltransferase YP_918272.1 KEGG: rsp:RSP_1339 formamidopyrimidine-DNA glycolase; TIGRFAM: formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase YP_918273.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rsp:RSP_1340 enoyl-CoA hydratase/isomerase YP_918274.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_918275.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: nha:Nham_3665 3-demethylubiquinone-9 3-methyltransferase YP_918276.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: pau:PA14_46720 hypothetical protein YP_918277.1 PFAM: regulatory protein, MarR; KEGG: nha:Nham_3666 transcriptional regulator, MarR family YP_918278.1 PFAM: regulatory protein, ArsR; KEGG: sme:SMc02639 transcription regulator protein YP_918279.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: sal:Sala_0458 hypothetical protein YP_918280.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mlo:mlr1197 hypothetical protein YP_918281.1 KEGG: mlo:mll0865 hypothetical protein YP_918282.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: bur:Bcep18194_A5393 glyoxalase/bleomycin resistance protein/dioxygenase YP_918283.1 PFAM: regulatory protein, MerR; KEGG: mes:Meso_2848 transcriptional regulator, MerR family YP_918285.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein, MarR; KEGG: pfo:Pfl_2408 transcriptional regulator, MarR family YP_918286.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pae:PA2679 hypothetical protein YP_918287.1 PFAM: regulatory protein, MarR; KEGG: xcb:XC_0601 transcriptional regulator MarR family YP_918288.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: bam:Bamb_5783 transcriptional regulator, AraC family YP_918289.1 PFAM: Na+/solute symporter; KEGG: btk:BT9727_3311 sodium/pantothenate symporter YP_918290.1 KEGG: dsy:DSY4724 hypothetical protein; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_918291.1 PFAM: protein of unknown function DUF849; KEGG: rpc:RPC_0103 protein of unknown function DUF849 YP_918293.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: pfl:PFL_5380 RNA polymerase sigma-70 factor, ECF subfamily YP_918294.1 PFAM: FecR protein; KEGG: pae:PA3409 probable transmembrane sensor YP_918295.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug; KEGG: rru:Rru_A1440 TonB-dependent siderophore receptor YP_918296.1 KEGG: bxe:Bxe_A3169 IS66 transposase, TnpC YP_918298.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein; KEGG: plu:plu1111 hypothetical protein YP_918299.1 PFAM: transposase IS66; KEGG: mag:amb3320 transposase and inactivated derivative YP_918301.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: rsp:RSP_2324 transcriptional regulator, RpiR family YP_918302.1 PFAM: N-formylglutamate amidohydrolase; KEGG: rsp:RSP_2323 hypothetical protein YP_918303.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: rsp:RSP_2322 TRAP-T family transporter, DctQ (4TMs) subunit YP_918304.1 PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: rsp:RSP_2321 TRAP-T family transporter, DctM (12TMs) subunit YP_918305.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rsp:RSP_2320 TRAP-T family transporter, periplasmic binding protein YP_918306.1 PFAM: glutamine synthetase, catalytic region; KEGG: rsp:RSP_2319 glutamine synthetase class-I YP_918307.1 PFAM: aldehyde dehydrogenase; KEGG: rsp:RSP_2318 aldehyde dehydrogenase YP_918308.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: rsp:RSP_2317 iron-containing alcohol dehydrogenase YP_918309.1 TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: rsp:RSP_0579 acetyl-coenzyme A synthetase YP_918310.1 KEGG: sit:TM1040_3665 conserved hypothetical protein YP_918311.1 PFAM: Na+/solute symporter; KEGG: rsp:RSP_0576 Na+/solute symporter YP_918312.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase KEGG: rsp:RSP_0575 predicted signal transduction protein containing cyclic nucleotide-binding and CBS domains YP_918313.1 KEGG: rsp:RSP_0574 hypothetical protein YP_918314.1 PFAM: response regulator receiver; KEGG: rsp:RSP_0573 response regulator receiver protein YP_918315.1 KEGG: rsp:RSP_0572 exonuclease; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_918316.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: sme:SMa0142 possible protease YP_918317.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sme:SMa0143 RpoE6 RNA polymerase sigma factor YP_918318.1 KEGG: sme:SMa0144 hypothetical protein YP_918319.1 PFAM: sodium/sulphate symporter; KEGG: sco:SCO2144 integral membrane transporter YP_918320.1 PFAM: glycerate kinase; KEGG: bat:BAS2054 glycerate kinase YP_918321.1 PFAM: Hemolysin-type calcium-binding region; KEGG: rpb:RPB_0805 glycerophosphoryl diester phosphodiesterase YP_918322.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bbr:BB1277 LysR-family transcriptional regulator YP_918323.1 stationary phase that binds TrpR repressor YP_918324.1 PFAM: major facilitator superfamily MFS_1; KEGG: mag:amb2984 permease of the major facilitator superfamily YP_918325.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: sme:SMc00381 hypothetical protein YP_918326.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_918329.1 KEGG: bur:Bcep18194_A6516 hypothetical protein YP_918330.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: mlo:mlr0241 hypothetical protein YP_918331.1 PFAM: major facilitator superfamily MFS_1; KEGG: neu:NE2492 general substrate transporters YP_918332.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: sil:SPO0261 hypothetical protein YP_918333.1 PFAM: aldo/keto reductase; KEGG: jan:Jann_0800 aldo/keto reductase YP_918334.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sme:SMa1632 LysR-family transcriptional regulator YP_918335.1 KEGG: rsp:RSP_2028 hypothetical protein YP_918336.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_2029 short chain dehydrogenase YP_918337.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: jan:Jann_0773 cupin 2 protein YP_918338.1 PFAM: helix-turn-helix, HxlR type; KEGG: ret:RHE_CH02586 transcriptional regulator protein YP_918339.1 PFAM: NADPH-dependent FMN reductase; Antibiotic biosynthesis monooxygenase; KEGG: mlo:mll2599 probable reductase YP_918340.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rme:Rmet_5666 transcriptional regulator, LysR family YP_918341.1 KEGG: cvi:CV1605 hypothetical protein YP_918342.1 PFAM: protein of unknown function DUF1330; KEGG: mlo:mll3541 hypothetical protein YP_918343.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sil:SPO3609 short chain dehydrogenase YP_918344.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_918345.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_918347.1 KEGG: ret:RHE_CH01244 probable molecular chaperone small heat shock protein, HSP20 family YP_918348.1 KEGG: ret:RHE_CH01245 probable molecular chaperone small heat shock protein, HSP20 family YP_918349.1 activates fatty acids by binding to coenzyme A YP_918350.1 PFAM: Rhodanese domain protein; KEGG: mes:Meso_2537 rhodanese-like YP_918351.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase; KEGG: rsp:RSP_3419 hypothetical protein YP_918352.1 TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductases; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: rpa:RPA4653 biotin sulfoxide reductase YP_918353.1 thiamine-pyrophosphate requiring enzyme YP_918354.1 PFAM: carbohydrate kinase, FGGY; KEGG: sme:SMc01623 erythritol kinase YP_918355.1 PFAM: class II aldolase/adducin family protein; KEGG: bja:bll6170 L-fuculose phosphate aldolase YP_918356.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mlo:mlr7269 phosphoglycerate dehydrogenase YP_918357.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pae:PA3592 hypothetical protein YP_918358.1 KEGG: rpa:RPA4652 possible CoA transferase, subunit B YP_918359.1 KEGG: rpa:RPA4651 possible glutaconate CoA-transferase, subunit A YP_918360.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rpa:RPA4650 spermidine/putrescine transport system ATP-binding protein YP_918361.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rpa:RPA4649 probable ABC transporter permease YP_918362.1 KEGG: rpa:RPA4648 possible ABC transporter binding protein component YP_918363.1 PFAM: regulatory protein, ArsR; regulatory proteins, IclR; KEGG: rpa:RPA4647 probable transcriptional regulator KdgR, IclR family YP_918364.1 KEGG: atc:AGR_L_2660 hypothetical protein YP_918365.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gbe:GbCGDNIH1_1531 biotin synthase related domain containing protein YP_918366.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: gbe:GbCGDNIH1_1530 uracil DNA glycosylase superfamily protein YP_918367.1 KEGG: jan:Jann_0955 general stress protein 26 YP_918368.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: rsp:RSP_0113 phospholipase D/transphosphatidylase YP_918369.1 PFAM: FAD dependent oxidoreductase; KEGG: hne:HNE_2468 oxidoreductase YP_918370.1 PFAM: Catalase domain protein; KEGG: hne:HNE_2467 catalase HPII YP_918371.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: jan:Jann_3999 peptidoglycan-binding domain 1 YP_918372.1 KEGG: bja:bll8025 hypothetical protein YP_918373.1 KEGG: rsp:RSP_0683 hypothetical protein YP_918374.1 TIGRFAM: esterase, PHB depolymerase family; PFAM: esterase; phospholipase/Carboxylesterase; KEGG: rru:Rru_A1969 esterase, PHB depolymerase YP_918375.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_918376.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: bja:blr6040 transcriptional regulatory protein YP_918377.1 PFAM: Asp/Glu racemase; KEGG: pol:Bpro_0550 Asp/Glu racemase YP_918378.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: pol:Bpro_0556 TRAP dicarboxylate transporter-DctP subunit YP_918379.1 KEGG: pol:Bpro_0557 hypothetical protein YP_918380.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: pol:Bpro_0558 TRAP dicarboxylate transporter-DctM subunit YP_918381.1 PFAM: amidohydrolase; KEGG: rde:RD1_2424 amidohydrolase family protein YP_918382.1 KEGG: hne:HNE_1970 dipeptidase family protein YP_918383.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: sit:TM1040_2780 transcriptional regulator, AsnC family YP_918384.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: sit:TM1040_2779 Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_918385.1 PFAM: protein of unknown function DUF161; KEGG: sme:SMc02240 hypothetical protein YP_918387.1 PFAM: FAD dependent oxidoreductase; KEGG: bja:bll4301 oxidoreductase YP_918388.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: sus:Acid_0469 peptidase S9B, dipeptidylpeptidase IV domain protein YP_918389.1 PFAM: regulatory protein, TetR; KEGG: mpa:MAP1349c hypothetical protein YP_918390.1 PFAM: major facilitator superfamily MFS_1; KEGG: bam:Bamb_5358 major facilitator superfamily MFS_1 YP_918391.1 PFAM: beta-lactamase; KEGG: bce:BC3013 D-alanyl-D-alanine carboxypeptidase YP_918392.1 PFAM: Uncharacterized conserved protein UCP012702; MlrC domain protein; KEGG: bur:Bcep18194_A4349 hypothetical protein YP_918393.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: ret:RHE_CH01456 leucine aminopeptidase YP_918394.1 PFAM: peptidase M42 family protein; KEGG: ava:Ava_3182 peptidases M20 and M42 YP_918395.1 PFAM: Carbohydrate-selective porin OprB; KEGG: plu:plu0581 porin YP_918396.1 catalyzes the formation of L-proline from L-ornithine YP_918398.1 KEGG: sdn:Sden_2083 hypothetical protein YP_918399.1 KEGG: mxa:MXAN_2365 hypothetical protein YP_918400.1 PFAM: tyrosinase; KEGG: hsa:7299 tyrosinase (oculocutaneous albinism IA) YP_918401.1 SMART: regulatory protein, AsnC/Lrp family; KEGG: eca:ECA1157 AsnC-family transcriptional regulator YP_918402.1 PFAM: regulatory protein, TetR; KEGG: reu:Reut_A1792 regulatory protein, TetR YP_918403.1 PFAM: cyclase family protein; KEGG: jan:Jann_2038 cyclase YP_918404.1 PFAM: major facilitator superfamily MFS_1; KEGG: pol:Bpro_2062 major facilitator superfamily MFS_1 YP_918405.1 PFAM: protein of unknown function DUF849; KEGG: rpc:RPC_0103 protein of unknown function DUF849 YP_918406.1 PFAM: extracellular solute-binding protein, family 1; KEGG: sth:STH3219 iron ABC transporter substrate-binding protein YP_918407.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sth:STH3218 ABC transporter permease YP_918408.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sth:STH3217 ABC transporter ATP-binding protein YP_918409.1 PFAM: inositol monophosphatase; KEGG: sme:SMb20159 inositol monophosphatase YP_918410.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: cvi:CV0148 probable transcriptional regulator YP_918411.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_918412.1 KEGG: bbr:BB1453 regulatory lipoprotein YP_918413.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: jan:Jann_1731 periplasmic sensor signal transduction histidine kinase YP_918414.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: ret:RHE_CH02973 two-component response regulator protein regulating C4-dicarboxylate transport system YP_918415.1 PFAM: extracellular solute-binding protein, family 1; KEGG: bpe:BP2271 regulatory lipoprotein YP_918416.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbr:BB1452 probable permease component of ABC transporter YP_918417.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: bbr:BB1451 probable ATP-binding component of ABC transporter YP_918418.1 PFAM: Phosphoglycerate mutase; KEGG: sus:Acid_7225 phosphoglycerate mutase YP_918419.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: aor:AO090023000033 pyridoxamine-phosphate oxidase Pfam: Pyridox_oxidase YP_918420.1 KEGG: ret:RHE_PB00156 hypothetical protein YP_918421.1 PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein; KEGG: mes:Meso_3972 shikimate dehydrogenase substrate binding-like YP_918422.1 PFAM: aldehyde dehydrogenase; KEGG: ccr:CC2791 fatty aldehyde dehydrogenase YP_918423.1 PFAM: dihydrodipicolinate synthetase; KEGG: mes:Meso_3971 dihydrodipicolinate synthetase YP_918424.1 PFAM: extracellular solute-binding protein, family 3; KEGG: rfr:Rfer_1029 extracellular solute-binding protein, family 3 YP_918425.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mes:Meso_3975 ABC transporter related YP_918426.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_980GM ABC transporter permease YP_918427.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_3976 polar amino acid ABC transporter, inner membrane subunit YP_918428.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain; KEGG: bms:BRA0806 hydrolase, UxaA family YP_918429.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: mes:Meso_3969 transcriptional regulator, GntR family YP_918430.1 PFAM: band 7 protein; KEGG: sit:TM1040_2195 band 7 protein YP_918431.1 PFAM: protein of unknown function DUF1449; KEGG: jan:Jann_1795 hypothetical protein YP_918432.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: ecp:ECP_3116 hypothetical phosphosugar isomerases YP_918433.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; dihydroorotate dehydrogenase; KEGG: rme:Rmet_0839 FMN-dependent alpha-hydroxy acid dehydrogenase YP_918434.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: rme:Rmet_0838 2OG-Fe(II) oxygenase YP_918435.1 KEGG: mfa:Mfla_2318 TonB-dependent siderophore receptor YP_918436.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_918437.1 PFAM: MaoC domain protein dehydratase; KEGG: rru:Rru_A2194 MaoC-like dehydratase YP_918438.1 PFAM: regulatory protein, TetR; KEGG: reu:Reut_B4322 regulatory protein, TetR YP_918439.1 TIGRFAM: PAS sensor protein; PFAM: regulatory protein, LuxR; PAS fold domain protein; KEGG: pen:PSEEN2542 PAS domain containing response regulator, LuxR family YP_918440.1 KEGG: rsp:RSP_1914 3-ketoacid CoA transferase alpha subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_918441.1 KEGG: rsp:RSP_1913 3-oxoadipate CoA-transferase, beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_918442.1 PFAM: secretion protein HlyD family protein; KEGG: rpc:RPC_4665 secretion protein HlyD YP_918443.1 PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase; KEGG: rpb:RPB_0170 ABC-2 type transport system YP_918444.1 PFAM: ABC-2 type transporter; KEGG: bmb:BruAb1_1347 hypothetical ABC transporter, permease YP_918445.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sme:SMc00385 hypothetical protein YP_918446.1 KEGG: zmo:ZMO1010 hypothetical protein YP_918447.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sit:TM1040_3086 phosphatidylethanolamine N-methyltransferase YP_918448.1 KEGG: sit:TM1040_3085 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_918449.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_918450.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: bme:BMEII0825 uracil permease YP_918451.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rpe:RPE_3985 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_918452.1 KEGG: rpb:RPB_0927 hypothetical protein YP_918453.1 PFAM: acriflavin resistance protein; KEGG: rsp:RSP_0460 AcrB/AcrD/AcrF family cation/multidrug efflux pump YP_918454.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: rsp:RSP_0461 multidrug/cation efflux pump, membrane fusion protein (MFP) family YP_918455.1 KEGG: rsp:RSP_0589 hypothetical protein YP_918456.1 PFAM: cytochrome B561; KEGG: rsp:RSP_0475 cytochrome b YP_918457.1 PFAM: cytochrome c, class II; KEGG: rsp:RSP_0474 cytochrome c' YP_918458.1 PFAM: regulatory protein, ArsR; KEGG: bja:bll5773 transcriptional regulatory protein YP_918459.1 PFAM: protein of unknown function DUF442; KEGG: bms:BRA0697 hypothetical protein YP_918460.1 PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: sit:TM1040_3646 protein of unknown function DUF395, YeeE/YedE YP_918461.1 PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: bur:Bcep18194_B1883 YeeE/YedE family membrane protein YP_918462.1 KEGG: rso:RSc1506 probable transmembrane protein YP_918463.1 PFAM: beta-lactamase domain protein; KEGG: mlo:mll3743 hypothetical protein YP_918464.1 KEGG: rde:RD1_2193 hypothetical protein YP_918465.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rsp:RSP_3237 lactoylglutathione lyase YP_918466.1 KEGG: rde:RD1_2191 hypothetical protein YP_918467.1 PFAM: glucose-methanol-choline oxidoreductase; KEGG: rde:RD1_2190 oxidoreductase YP_918468.1 TIGRFAM: cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; KEGG: dps:DP0668 probable cell division topological specificity factor (MinE) YP_918469.1 TIGRFAM: septum site-determining protein MinD; KEGG: pfl:PFL_4380 septum site-determining protein MinD YP_918470.1 TIGRFAM: septum site-determining protein MinC; PFAM: Septum formation inhibitor MinC; KEGG: aeh:Mlg_1998 septum site-determining protein MinC YP_918471.1 PFAM: phosphoribosyltransferase; KEGG: mes:Meso_3530 phosphoribosyltransferase YP_918472.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sit:TM1040_3319 TRAP dicarboxylate transporter, DctP subunit YP_918473.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: sit:TM1040_3318 tripartite ATP-independent periplasmic transporter, DctQ component YP_918474.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sit:TM1040_3317 TRAP dicarboxylate transporter-DctM subunit YP_918476.1 PFAM: periplasmic nitrate reductase NapE; KEGG: sme:SMa1241 NapE component of periplasmic nitrate reductase YP_918477.1 PFAM: NapD family protein; KEGG: sme:SMa1239 NapD component of periplasmic nitrate reductase YP_918478.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_918479.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: sme:SMa1233 NapB periplasmic nitrate reductase YP_918480.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: sme:SMa1232 NapC membrane protein, e-donor to periplasmic nitrate reductase YP_918481.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_918482.1 KEGG: rpd:RPD_2427 hypothetical protein YP_918483.1 PFAM: MscS Mechanosensitive ion channel; KEGG: eba:ebA6709 mechanosensitive channel protein YP_918484.1 PFAM: glucose sorbosone dehydrogenase; KEGG: neu:NE1997 glucose dehydrogenase B YP_918485.1 PFAM: regulatory protein, LysR; helix-turn-helix, Fis-type; LysR, substrate-binding; KEGG: bja:bll5630 transcriptional regulatory protein YP_918486.1 KEGG: mfa:Mfla_0547 hypothetical protein YP_918487.1 KEGG: mfa:Mfla_0548 amine dehydrogenase; TIGRFAM: methylamine dehydrogenase heavy chain; PFAM: methylamine dehydrogenase heavy subunit YP_918488.1 PFAM: methylamine utilisation MauE; KEGG: mfa:Mfla_0549 methylamine utilisation MauE YP_918489.1 TIGRFAM: methylamine dehydrogenase accessory protein MauD; PFAM: Redoxin domain protein; KEGG: mfa:Mfla_0550 hypothetical protein YP_918490.1 KEGG: mfa:Mfla_0551 amine dehydrogenase; TIGRFAM: methylamine dehydrogenase light chain; PFAM: Methylamine dehydrogenase light chain, C terminal domain protein YP_918491.1 TIGRFAM: amicyanin; PFAM: blue (type 1) copper domain protein; KEGG: mpa:MAP4219 hypothetical protein YP_918493.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: atc:AGR_C_5068 hypothetical protein YP_918494.1 TIGRFAM: MauM/NapG family ferredoxin-type protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mfa:Mfla_0554 MauM/NapG family ferredoxin-type protein YP_918495.1 TIGRFAM: ferredoxin-type protein, NapH/MauN family; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: dar:Daro_3838 ferredoxin-type protein, NapH/MauN family YP_918496.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein-like; KEGG: rsp:RSP_3090 alkylphosphonate uptake protein, PhnA YP_918497.1 PFAM: regulatory protein, LuxR; KEGG: rme:Rmet_5323 two component transcriptional regulator, LuxR family YP_918498.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: ret:RHE_PF00324 probable two-component sensor histidine kinase/response regulator hybrid protein YP_918499.1 KEGG: cvi:CV2214 hypothetical protein YP_918500.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: jan:Jann_3999 peptidoglycan-binding domain 1 YP_918501.1 KEGG: mlo:mlr2623 hypothetical protein YP_918502.1 PFAM: Sel1 domain protein repeat-containing protein YP_918503.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ret:RHE_PF00392 probable glycine betaine/L-proline ABC transporter, permease YP_918504.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ret:RHE_PF00393 probable glycine betaine/L-proline ABC transporter, permease YP_918505.1 KEGG: ret:RHE_PF00394 probable glycine betaine/L-proline ABC transporter, ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_918506.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: ret:RHE_PF00395 probable glycine betaine/L-proline ABC transporter, substrate-binding protein YP_918507.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bur:Bcep18194_C7696 transcriptional regulator, LysR family YP_918508.1 PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_4005 oxidoreductase, NAD-binding site YP_918509.1 PFAM: aldehyde dehydrogenase; KEGG: rsp:RSP_4003 aldehyde dehydrogenase YP_918510.1 PFAM: dihydrodipicolinate synthetase; KEGG: rsp:RSP_4002 dihydrodipicolinate synthetase YP_918511.1 KEGG: reu:Reut_B3732 hypothetical protein YP_918512.1 PFAM: carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated; KEGG: sme:SMc04382 beta-(1,2)-glucan production associated transmembrane protein YP_918513.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: atu:Atu4818 transcriptional regulator, AsnC family YP_918514.1 PFAM: dehydrogenase, E1 component; KEGG: bme:BMEII0748 2-oxoisovalerate dehydrogenase alpha subunit YP_918515.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: mlo:mll4472 2-oxoisovalerate dehydrogenase (beta subunit) YP_918516.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: bms:BRA0526 2-oxoisovalerate dehydrogenase E2 component, dihydrolipoamide acetyltransferase YP_918517.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mlo:mll4470 dihydrolipoamide dehydrogenase YP_918518.1 PFAM: protein of unknown function DUF105; KEGG: rsp:RSP_2406 hypothetical protein YP_918519.1 KEGG: sit:TM1040_3771 conserved hypothetical protein YP_918520.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: sme:SMb20613 C4-dicarboxylate transport transcriptional regulatory protein YP_918521.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: mlo:mlr5841 dicarboxylate sensor protein YP_918522.1 PFAM: sodium:dicarboxylate symporter; KEGG: atc:AGR_L_3041 C4-dicarboxylate transport protein YP_918523.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: rsp:RSP_1243 transcriptional regulator, LacI family YP_918524.1 PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: bms:BR0545 hypothetical protein YP_918525.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: atc:AGR_L_984 hypothetical protein YP_918526.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_1247 ABC sugar transporter, ATPase subunit YP_918527.1 PFAM: inner-membrane translocator; KEGG: rsp:RSP_6150 ABC sugar (ribose) transporter, inner membrane subunit YP_918528.1 KEGG: rsp:RSP_1249 ABC ribose transporter, periplasmic solute-binding protein YP_918529.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_918530.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: rsp:RSP_0606 redox protein YP_918531.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: Amidohydrolase 3; KEGG: sil:SPO0476 alkylphosphonate utilization protein PhnM YP_918532.1 PFAM: protein of unknown function DUF1045; KEGG: rsp:RSP_2937 hypothetical protein YP_918533.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: jan:Jann_2855 phosphonate metabolism, 1,5-bisphosphokinase (PRPP-forming) PhnN YP_918534.1 KEGG: sit:TM1040_3698 phosphonate C-P lyase system, PhnL; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase YP_918535.1 KEGG: rde:RD1_2390 phosphonate C-P lyase system protein PhnK; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase YP_918536.1 PFAM: phosphonate metabolism PhnJ; KEGG: rde:RD1_2391 phosphonate metabolism protein PhnJ YP_918537.1 PFAM: phosphonate metabolism; KEGG: rde:RD1_2392 phosphonate metabolism protein YP_918538.1 PFAM: phosphonate metabolism; KEGG: rde:RD1_2393 phosphonate metabolism protein YP_918539.1 PFAM: phosphonate metabolism PhnG; KEGG: sit:TM1040_3703 phosphonate metabolism PhnG YP_918540.1 TIGRFAM: phosphonates metabolism transcriptional regulator PhnF; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: sil:SPO0467 transcriptional regulator, GntR family YP_918541.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sil:SPO0783 phosphonate ABC transporter, permease YP_918542.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sil:SPO0782 phosphonate ABC transporter, permease YP_918543.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: sit:TM1040_3708 phosphonate-binding periplasmic protein YP_918544.1 KEGG: sit:TM1040_3709 phosphonate ABC transporter PhnC, ATP-binding; TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_918546.1 PFAM: NADPH-dependent FMN reductase; KEGG: rsp:RSP_3069 NADPH-dependent FMN reductase YP_918547.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: mlo:mll0364 hypothetical protein YP_918548.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_918549.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: rsp:RSP_3535 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme YP_918550.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bbr:BB3153 high-affinity branched-chain amino acid transport, ATP-binding protein YP_918551.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bpe:BP1649 high-affinity branched-chain amino acid transport, ATP-binding protein YP_918552.1 PFAM: inner-membrane translocator; KEGG: bbr:BB3151 ABC-transporter permease component YP_918553.1 PFAM: inner-membrane translocator; KEGG: bbr:BB3150 ABC-transporter permease component YP_918554.1 PFAM: Extracellular ligand-binding receptor; KEGG: bpa:BPP2828 ABC-transporter substrate-binding protein YP_918555.1 TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: aldehyde dehydrogenase; KEGG: bbr:BB3430 oxidoreductase YP_918556.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_918557.1 TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; KEGG: nha:Nham_0937 phenylacetic acid degradation protein PaaD YP_918558.1 TIGRFAM: phenylacetate-CoA ligase; KEGG: jan:Jann_0656 phenylacetate-CoA ligase YP_918559.1 PFAM: regulatory protein, TetR; KEGG: nha:Nham_0935 transcriptional regulator, TetR family YP_918560.1 KEGG: sme:SMa2315 aminoglycoside adenylyltransferase YP_918561.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_918562.1 PFAM: phenylacetic acid catabolic family protein; KEGG: nha:Nham_0933 phenylacetic acid catabolic YP_918563.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: nha:Nham_0932 ferredoxin YP_918564.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: nha:Nham_0931 phenylacetate-CoA oxygenase, PaaJ subunit YP_918565.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: nha:Nham_0930 phenylacetate-CoA oxygenase, PaaI subunit YP_918566.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_918567.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_918568.1 KEGG: dar:Daro_0375 thiolase; TIGRFAM: acetyl-CoA acetyltransferases; beta-ketoadipyl CoA thiolase; PFAM: Thiolase YP_918569.1 PFAM: PaaX domain protein; PaaX domain protein, C-terminal domain; KEGG: sme:SMb21641 regulator of phenylacetic acid degradation, ArsR family protein YP_918570.1 PFAM: peptidase S45, penicillin amidase; KEGG: sbo:SBO_4393 penicillin G acylase YP_918571.1 KEGG: hne:HNE_3363 hypothetical protein YP_918572.1 KEGG: hne:HNE_3362 hypothetical protein YP_918573.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: atc:AGR_L_113 hypothetical protein YP_918574.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: bja:blr4511 probable ABC transporter substrate-binding protein YP_918575.1 PFAM: regulatory proteins, IclR; KEGG: sme:SMc00263 transcription regulator protein YP_918576.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_918577.1 activates fatty acids by binding to coenzyme A YP_918578.1 KEGG: atc:AGR_L_127 hypothetical protein YP_918579.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: pol:Bpro_0097 short-chain dehydrogenase/reductase SDR YP_918580.1 KEGG: nha:Nham_1901 membrane protein YP_918581.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: ftf:FTF1447c phosphomannomutase YP_918582.1 KEGG: mfa:Mfla_1168 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; SMART: AAA ATPase YP_918583.1 KEGG: sit:TM1040_2140 hypothetical protein YP_918584.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rpb:RPB_0102 TonB-dependent siderophore receptor YP_918585.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sco:SCO0998 Fe uptake system permease YP_918586.1 PFAM: periplasmic binding protein; KEGG: rde:RD1_3480 iron ABC transporter, periplasmic binding protein YP_918587.1 PFAM: transport system permease; KEGG: rde:RD1_3479 hemin ABC transport protein, permease component YP_918588.1 PFAM: Negative transcriptional regulator; KEGG: rme:Rmet_4524 negative transcriptional regulator YP_918589.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: mlo:mlr6174 transcriptional regulator YP_918590.1 PFAM: AraC protein, arabinose-binding/dimerisation; SMART: helix-turn-helix- domain containing protein, AraC type; KEGG: pae:PA0791 probable transcriptional regulator YP_918591.1 PFAM: major facilitator superfamily MFS_1; KEGG: sus:Acid_6582 major facilitator superfamily MFS_1 YP_918592.1 PFAM: regulatory protein GntR, HTH; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; KEGG: bja:blr0404 transcriptional regulatory protein YP_918593.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: bja:bll0403 hypothetical protein YP_918594.1 KEGG: xfa:XF1750 hypothetical protein YP_918595.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ret:RHE_CH01779 hydrolase, haloacid dehalogenase-like family YP_918596.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_L_3295 hypothetical protein YP_918597.1 Converts D-sorbitol to L-sorbose YP_918598.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_0094 ABC sorbitol/mannitol transporter, ATPase subunit YP_918599.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0093 ABC sorbitol/mannitol transporter, inner membrane subunit YP_918600.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_0092 ABC sorbitol/mannitol transporter, inner membrane subunit YP_918601.1 PFAM: extracellular solute-binding protein, family 1; KEGG: atc:AGR_L_3289 periplasmic sorbitol-binding protein YP_918602.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein, LacI; KEGG: rde:RD1_1487 transcriptional regulator, LacI family YP_918603.1 PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: sme:SMb21373 sugar kinase YP_918604.1 PFAM: PfkB domain protein; KEGG: sme:SMb21374 sugar kinase, PfkB family protein YP_918605.1 PFAM: inner-membrane translocator; KEGG: sme:SMb21375 sugar uptake ABC transporter permease YP_918606.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb21376 sugar uptake ABC transporter ATP-binding protein YP_918607.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb21377 sugar uptake ABC transporter periplasmic solute-binding protein precursor YP_918608.1 PFAM: Sel1 domain protein repeat-containing protein; peptidase C14, caspase catalytic subunit p20; SMART: peptidase C14, caspase precursor p45; KEGG: ret:RHE_PE00124 hypothetical protein YP_918609.1 KEGG: rno:678915 hypothetical protein LOC678915 YP_918610.1 PFAM: protein of unknown function DUF126; protein of unknown function DUF521; KEGG: sme:SMb20269 hypothetical protein YP_918611.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: pau:PA14_48020 L-malate dehydrogenase YP_918612.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: bja:bll4424 hypothetical protein YP_918613.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: bja:bll4425 hypothetical protein YP_918614.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: bja:bll4426 hypothetical protein YP_918615.1 PFAM: proline racemase; KEGG: sme:SMb20268 proline racemase YP_918616.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMb20267 D-amino acid dehydrogenase YP_918617.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_L_402 probable ATP-binding component of ABC transporter YP_918618.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_403 probable permease of ABC transporter YP_918619.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_405 probable permease of ABC transporter YP_918620.1 PFAM: extracellular solute-binding protein, family 3; KEGG: sme:SMb20263 ABC transporter periplasmic amino acid-binding protein YP_918621.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMb20262 semialdehyde dehydrogenase YP_918622.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: sme:SMb20261 malate dehydrogenase YP_918623.1 PFAM: dihydrodipicolinate synthetase; KEGG: sme:SMb20259 dihydrodipicolinate synthase YP_918624.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sme:SMb20258 transcriptional regulator protein YP_918625.1 KEGG: mlo:mll7204 ABC transporter, substrate binding protein YP_918626.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: ppr:PBPRB1321 transcriptional regulator, HTH_3family YP_918627.1 KEGG: rsp:RSP_3364 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent YP_918628.1 PFAM: FAD linked oxidase domain protein; KEGG: eba:ebA4737 FAD dependent oxidoreductase YP_918629.1 KEGG: pae:PA4985 spermidine/putrescine transport system substrate-binding protein YP_918630.1 KEGG: mes:Meso_2369 spermidine/putrescine ABC transporter ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_918631.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mes:Meso_1937 binding-protein-dependent transport systems inner membrane component YP_918632.1 PFAM: dihydrodipicolinate synthetase; KEGG: bbr:BB1108 dihydrodipicolinate synthase YP_918633.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: bpe:BP1669 lactate dehydrogenase YP_918634.1 PFAM: pyruvate carboxyltransferase; KEGG: jan:Jann_3783 pyruvate carboxyltransferase YP_918635.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: bja:blr0697 hypothetical protein YP_918636.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bja:bll0696 transcriptional regulatory protein YP_918637.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: rpd:RPD_2108 extracellular solute-binding protein, family 3 YP_918638.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bja:bll6487 ABC transporter permease YP_918639.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bmb:BruAb2_0894 ABC transporter, ATP binding protein YP_918641.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: csa:Csal_2353 binding-protein-dependent transport systems inner membrane component YP_918642.1 KEGG: sme:SMa1466 probable ABC transporter ATP binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_918643.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: csa:Csal_2355 binding-protein-dependent transport systems inner membrane component YP_918644.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: csa:Csal_2356 substrate-binding region of ABC-type glycine betaine transport system YP_918645.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: csa:Csal_2359 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_918646.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: bxe:Bxe_B1084 butyryl-CoA dehydrogenase YP_918647.1 PFAM: AMP-dependent synthetase and ligase; KEGG: bce:BC0890 acyl-CoA synthase YP_918648.1 PFAM: MmgE/PrpD family protein; KEGG: csa:Csal_2358 MmgE/PrpD YP_918649.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: mlo:mlr6509 transcriptional regulator YP_918650.1 PFAM: FAD dependent oxidoreductase; KEGG: bxe:Bxe_B0746 oxidoreductase YP_918651.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: pol:Bpro_0689 BFD-like (2Fe-2S)-binding region YP_918652.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mlo:mll5100 ferredoxin [2Fe-2S] I YP_918653.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: ppu:PP_0315 rieske 2Fe-2S family protein YP_918655.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase; KEGG: bja:bll6900 hypothetical protein YP_918656.1 KEGG: bja:bll6901 hypothetical protein YP_918657.1 PFAM: luciferase family protein; KEGG: bja:bll6902 hypothetical protein YP_918658.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: eca:ECA0072 ABC transporter ATP-binding protein YP_918659.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eca:ECA0073 ABC transporter permease YP_918660.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_918661.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_918662.1 PFAM: Sarcosine oxidase, gamma subunit; KEGG: rde:RD1_0009 sarcosine oxidase, gamma subunit YP_918663.1 TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein, C-terminal barrel; KEGG: sit:TM1040_3377 sarcosine oxidase, alpha subunit family YP_918664.1 PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rde:RD1_0011 sarcosine oxidase, delta subunit YP_918665.1 TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: sit:TM1040_3375 sarcosine oxidase, beta subunit family YP_918666.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: mlo:mlr6241 transcription regulator YP_918667.1 KEGG: bbr:BB1042 extracellular solute-binding protein YP_918668.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bbr:BB1044 inner membrane component of ABC transporter YP_918669.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: bbr:BB1043 ATP-binding component of ABC transporter YP_918670.1 PFAM: inositol monophosphatase; KEGG: sme:SMa0483 inositol monophosphatase YP_918671.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: bxe:Bxe_A4204 transcriptional regulator, DeoR family YP_918672.1 PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: sme:SMc01662 sarcosine dehydrogenase YP_918673.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: sil:SPO3403 DNA-binding protein YP_918674.1 KEGG: rru:Rru_B0014 transposase, mutator type YP_918675.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_918676.1 KEGG: vvy:VV0790 hypothetical protein YP_918677.1 PFAM: alpha/beta hydrolase fold; KEGG: lbl:LBL_2370 hydrolase YP_918678.1 KEGG: gox:GOX0022 hypothetical protein YP_918679.1 PFAM: regulatory proteins, IclR; KEGG: bam:Bamb_0518 transcriptional regulator, IclR family YP_918680.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rfr:Rfer_1032 amino acid ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine YP_918681.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rfr:Rfer_1031 amino acid ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine YP_918682.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mes:Meso_3975 ABC transporter related YP_918683.1 PFAM: extracellular solute-binding protein, family 3; KEGG: rfr:Rfer_1029 extracellular solute-binding protein, family 3 YP_918684.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain; KEGG: rfr:Rfer_1027 galactarate dehydratase YP_918685.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: ret:RHE_CH00854 2-dehydro-3-deoxygalactonokinase YP_918686.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_918687.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bth:BT3617 sorbitol dehydrogenase YP_918688.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: mmr:Mmar10_0232 2-deoxy-D-gluconate 3-dehydrogenase YP_918689.1 KEGG: sme:SMa2229 hypothetical protein YP_918690.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMa2225 opine oxidase subunit YP_918691.1 KEGG: bxe:Bxe_B2707 hypothetical protein YP_918692.1 PFAM: FAD dependent oxidoreductase; KEGG: sme:SMa2223 opine oxidase subunit YP_918693.1 KEGG: sme:SMa2221 hypothetical protein YP_918694.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: sme:SMa2219 probable decarboxylase YP_918695.1 TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: sme:SMa2217 decarboxylase YP_918696.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: sme:SMa2215 GntR-family transcriptional regulator YP_918697.1 PFAM: aldehyde dehydrogenase; KEGG: sme:SMA2213 aldehyde YP_918698.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit YP_918699.1 PFAM: extracellular solute-binding protein, family 1; KEGG: sme:SMa2209 ABC transporter, periplasmic solute-binding protein YP_918700.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sme:SMa2207 ABC transporter, ATP-binding protein YP_918701.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa2205 ABC transporter, permease YP_918702.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa2203 ABC transporter, permease YP_918703.1 PFAM: protein of unknown function DUF1127; KEGG: rde:RD1_2086 hypothetical protein YP_918705.1 PFAM: protein of unknown function DUF72; KEGG: rsp:RSP_0939 hypothetical protein YP_918707.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: mlo:mlr8292 probable N-methylproline demethylase (stahydrine utilization protein StcD) YP_918708.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bja:blr6829 transcriptional regulatory protein YP_918709.1 PFAM: ammonia monooxygenase; KEGG: rsp:RSP_7367 AbrB protein (AidB regulator) YP_918710.1 KEGG: ret:RHE_PF00334 acetyltransferase YP_918711.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: atc:AGR_L_1801 deaminase YP_918712.1 PFAM: FAD dependent oxidoreductase; KEGG: ret:RHE_PF00361 probable deaminase YP_918713.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: ret:RHE_PF00360 probable transcriptional regulator protein (leucine-responsive), AsnC family YP_918714.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa1864 ABC transporter, ATP-binding protein YP_918715.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ret:RHE_PF00353 probable oligopeptide ABC transporter, permease YP_918716.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa1862 ABC transporter, permease YP_918717.1 PFAM: extracellular solute-binding protein, family 5; KEGG: ret:RHE_PF00351 probable oligopeptide ABC transporter, substrate-binding protein YP_918718.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: atc:AGR_L_2827 hypothetical protein YP_918719.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: mlo:mll7048 probable dehydrogenase YP_918720.1 PFAM: aminotransferase class-III; KEGG: sme:SMa1855 hypothetical protein YP_918721.1 PFAM: GCN5-related N-acetyltransferase; KEGG: atc:AGR_L_2832 hypothetical protein YP_918722.1 PFAM: protein of unknown function DUF861, cupin_3; KEGG: mlo:mll7047 hypothetical protein YP_918723.1 PFAM: FAD dependent oxidoreductase; KEGG: mlo:mlr7042 probable oxidoreductase YP_918724.1 TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ret:RHE_PF00342 probable dehalogenase YP_918725.1 KEGG: sme:SMa1848 GabD5 succinate semialdehyde dehdyrogenase; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_918726.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_918727.1 PFAM: aldehyde dehydrogenase; KEGG: ret:RHE_PF00338 probable aldehyde dehydrogenase YP_918728.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mlo:mlr7023 transcriptional regulator YP_918729.1 PFAM: Hydantoinase B/oxoprolinase; KEGG: bpe:BP0821 hydantoin utilization protein B YP_918730.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: bbr:BB3858 hydantoin utilization protein A YP_918731.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vpa:VP2001 hypothetical protein YP_918732.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_918734.1 KEGG: pfa:PF10_0374 gene 11-1 protein precursor YP_918735.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: sil:SPO3788 acetoin catabolism regulatory protein YP_918736.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_L_281 hypothetical protein YP_918737.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: sil:SPO3789 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein YP_918738.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: rha:RHA1_ro05279 acetoin dehydrogenase YP_918739.1 PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; PGAP1 family protein; KEGG: sil:SPO3790 dihydrolipoamide acetyltransferase YP_918740.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: sil:SPO3791 acetoin dehydrogenase complex, E1 component, beta subunit YP_918741.1 PFAM: dehydrogenase, E1 component; KEGG: sil:SPO3792 acetoin dehydrogenase complex, E1 component, alpha subunit YP_918742.1 PFAM: ATP-NAD/AcoX kinase; KEGG: sil:SPO3793 acetoin catabolism protein X YP_918743.1 PFAM: sigma-54 factor, core-binding region; sigma-54, DNA-binding domain protein; KEGG: sil:SPO3795 RNA polymerase sigma-54 factor YP_918744.1 PFAM: protein of unknown function UPF0118; KEGG: bms:BRA0460 hypothetical protein YP_918745.1 PFAM: DSBA oxidoreductase; KEGG: sil:SPOA0362 27kDa outer membrane protein YP_918746.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: rsp:RSP_3073 ErfK/YbiS/YcfS/YnhG family protein YP_918747.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rfr:Rfer_1643 alcohol dehydrogenase, zinc-binding YP_918748.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mes:Meso_1938 enoyl-CoA hydratase/isomerase YP_918749.1 PFAM: major facilitator superfamily MFS_1; KEGG: mmr:Mmar10_2043 major facilitator superfamily MFS_1 YP_918750.1 PFAM: Extracellular ligand-binding receptor; KEGG: sit:TM1040_2237 extracellular ligand-binding receptor YP_918751.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sil:SPO2543 transcriptional regulator, GntR family YP_918752.1 PFAM: CoA-binding domain protein; ATP-grasp domain protein; KEGG: sma:SAV1821 acyl-CoA synthetase (NDP forming type) YP_918753.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rfr:Rfer_2387 ABC transporter related YP_918754.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tth:TTC0969 branched-chain amino acid transport ATP-binding protein livG YP_918755.1 PFAM: inner-membrane translocator; KEGG: reu:Reut_C6328 inner-membrane translocator YP_918756.1 PFAM: inner-membrane translocator; KEGG: bja:bll6235 ABC transporter permease YP_918757.1 PFAM: HupE/UreJ protein; KEGG: pfo:Pfl_0560 HupE/UreJ protein YP_918758.1 SMART: Rhodanese domain protein YP_918759.1 PFAM: Cupin domain protein; Cupin 2, conserved barrel domain protein; KEGG: bja:blr2407 hypothetical protein YP_918760.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sma:SAV1559 ABC transporter ATP-binding protein YP_918761.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sma:SAV1558 ABC transporter transmembrane subunit, permease YP_918762.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; SMART: extracellular solute-binding protein, family 3; KEGG: pau:PA14_30540 periplasmic aliphatic sulfonate-binding protein YP_918763.1 KEGG: pst:PSPTO_2425 monooxygenase, NtaA/SnaA/SoxA family YP_918764.1 PFAM: copper resistance protein CopC; copper resistance D domain protein; KEGG: rpa:RPA2929 copper resistance protein YP_918765.1 KEGG: rpc:RPC_2425 nuclear export factor GLE1 YP_918766.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bam:Bamb_3676 ABC transporter related YP_918767.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: bxe:Bxe_C0115 ABC nitrate/sulfonate/bicarbonate family transporter, inner membrane subunit YP_918768.1 KEGG: bja:bll6455 ABC transporter substrate-binding protein YP_918769.1 PFAM: luciferase family protein; KEGG: psb:Psyr_3599 alkanesulfonate monooxygenase YP_918770.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: bja:bll6452 acyl-CoA dehydrogenase YP_918772.1 KEGG: rpc:RPC_3638 serine O-acetyltransferase YP_918773.1 KEGG: bmb:BruAb2_0725 hypothetical protein YP_918774.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: rde:RD1_3783 hypothetical protein YP_918775.1 TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: regulatory proteins, IclR; KEGG: atc:AGR_L_644 PcaR protein YP_918776.1 KEGG: bmb:BruAb2_0588 PcaI, 3-oxoadipate CoA-transferase, alpha subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_918777.1 KEGG: atc:AGR_L_642 3-oxoacid CoA-transferase subunit B; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_918778.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_918779.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: mag:amb1437 nucleoside-diphosphate-sugar epimerase YP_918781.1 TIGRFAM: cytidyltransferase-related domain; glycerol-3-phosphate cytidylyltransferase; PFAM: cytidylyltransferase; KEGG: blo:BL0210 probable glycerol-3-phosphate cytidylyltransferase YP_918783.1 PFAM: glycosyl transferase, group 1; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: lxx:Lxx17460 teichoic acid synthase YP_918784.1 KEGG: sit:TM1040_1773 conserved hypothetical protein YP_918785.1 KEGG: ecc:c3693 hypothetical protein YP_918786.1 KEGG: ecc:c3695 hypothetical protein YP_918787.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rsp:RSP_2175 ABC transporter, ATPase subunit YP_918788.1 PFAM: cobalt transport protein; KEGG: rsp:RSP_2174 ABC transporter, inner membrane subunit YP_918789.1 PFAM: BioY protein; KEGG: rsp:RSP_2173 biotin biosynthesis protein BioY YP_918790.1 PFAM: initiator RepB protein; KEGG: cbu:CBUA0039 RepA protein YP_918791.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: sme:SMb20046 probable replication protein A YP_918792.1 TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: cbu:CBUA0038 RepB protein YP_918793.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20832 cell surface polysaccharide export ABC-2 transporter ATP-binding protein YP_918794.1 KEGG: mes:Meso_2756 capsule polysaccharide export protein-like YP_918795.1 PFAM: ABC-2 type transporter; KEGG: sme:SMb20833 cell surface polysaccharide export ABC-2 transporter permease, close relative of Y20822wzm2 YP_918796.1 PFAM: glycosyl transferase, group 1; KEGG: dvu:DVU0328 glycosyl transferase, group 1 family protein YP_918797.1 KEGG: msu:MS0656 hypothetical protein YP_918799.1 PFAM: UDP-galactopyranose mutase; KEGG: atc:AGR_L_1762 probable UDP-galactopyranose mutase YP_918800.1 PFAM: aldo/keto reductase; KEGG: mlo:mll3531 hypothetical protein YP_918801.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: mes:Meso_3045 FMN-dependent alpha-hydroxy acid dehydrogenase YP_918802.1 PFAM: regulatory protein, MarR; KEGG: mlo:mlr3448 regulatory protein (MarR-family) YP_918803.1 PFAM: extracellular solute-binding protein, family 1; KEGG: bja:bll3286 ABC transporter substrate-binding protein YP_918804.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: rsp:RSP_3396 ABC opine/polyamine transporter, ATPase subunit YP_918805.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pol:Bpro_4378 binding-protein-dependent transport systems inner membrane component YP_918806.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rsp:RSP_3518 ABC polyamine/opine transporter, inner membrane subunit YP_918807.1 PFAM: polysaccharide deacetylase; KEGG: bja:bll7202 hypothetical protein YP_918808.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: rsp:RSP_7370 short-chain alcohol dehydrogenase YP_918809.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: rsp:RSP_3963 short-chain dehydrogenase/reductase SDR YP_918810.1 PFAM: Amidase; KEGG: bja:blr3229 glutamyl-tRNA(Gln) amidotransferase subunit YP_918811.1 PFAM: ABC-2 type transporter; KEGG: mlo:mlr4596 ABC transporter, ATP-binding protein YP_918812.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mlo:mlr4595 ATP-binding component of a transport system YP_918813.1 PFAM: secretion protein HlyD family protein; KEGG: bmb:BruAb2_0759 HlyD family secretion protein YP_918814.1 PFAM: regulatory protein, TetR; KEGG: mes:Meso_4073 transcriptional regulator, TetR family YP_918815.1 PFAM: PfkB domain protein; KEGG: sil:SPO2420 2-dehydro-3-deoxygluconokinase YP_918816.1 PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain; KEGG: sil:SPO1724 D-mannonate oxidoreductase YP_918817.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_918818.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: pau:PA14_33860 L-lactate dehydrogenase YP_918819.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sil:SPO2424 L-idonate 5-dehydrogenase YP_918820.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sil:SPO1719 TRAP dicarboxylate transporter, DctM subunit YP_918821.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: sil:SPO1720 TRAP dicarboxylate transporter, DctQ subunit YP_918822.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: rde:RD1_1052 C4-dicarboxylate transport system, substrate-binding protein YP_918823.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sme:SMa0065 GntR-family transcriptional regulator YP_918824.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sme:SMc02596 transcription regulator protein YP_918825.1 KEGG: nwi:Nwi_0592 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_918826.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: atc:AGR_pAT_bx241 hypothetical protein YP_918827.1 PFAM: protein of unknown function DUF849; KEGG: atc:AGR_pAT_488 hypothetical protein YP_918828.1 PFAM: extracellular solute-binding protein, family 5; KEGG: atc:AGR_pAT_490 OphA, peptide transport system substrate-binding protein YP_918829.1 Converts (S)-3-hydroxyacyl-CoA to 3-oxyacyl-CoA; may also act as a thioesterase YP_918830.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_pAT_494 ABC transporter, permease YP_918831.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_pAT_496 ABC transporter, permease YP_918832.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: atc:AGR_pAT_497 ABC transporter ATP-binding protein YP_918833.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: atc:AGR_pAT_499 hypothetical protein YP_918834.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMa0078 LacI-family transcriptional regulator YP_918835.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0079 ABC transporter permease YP_918836.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMa0081 ABC transporter permease YP_918837.1 PFAM: extracellular solute-binding protein, family 3; KEGG: sme:SMa0082 ABC transporter, periplasmic solute-binding protein YP_918838.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMa0083 ABC transporter ATP-binding protein YP_918839.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: atc:AGR_L_379 hypothetical protein YP_918840.1 PFAM: PfkB domain protein; KEGG: psb:Psyr_2510 carbohydrate kinase, PfkB YP_918841.1 KEGG: bte:BTH_II1322 hydratase/decarboxylase family protein YP_918842.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: rxy:Rxyl_1761 3-hydroxybutyryl-CoA dehydrogenase YP_918843.1 catalyzes the conversion of salicylyl-CoA to gentisyl-CoA YP_918844.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: mlo:mll5433 similar to granaticin polyketide ketoreductase YP_918845.1 PFAM: regulatory protein, MarR; KEGG: mlo:mll5432 transcriptional regulator YP_918846.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_918847.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: mlo:mll5430 acyl-CoA dehydrogenase YP_918848.1 PFAM: thioesterase superfamily protein; KEGG: sil:SPO0786 thioesterase family protein YP_918849.1 PFAM: Endoribonuclease L-PSP; KEGG: mlo:mll5429 hypothetical protein YP_918850.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sil:SPOA0401 benzoate-coenzyme A ligase YP_918851.1 KEGG: rde:RD1_0540 ABC transporter substrate binding protei YP_918852.1 PFAM: inner-membrane translocator; KEGG: sit:TM1040_2236 inner-membrane translocator YP_918853.1 PFAM: inner-membrane translocator; KEGG: rde:RD1_0542 branched-chain amino acid ABC transporter, permease YP_918854.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sit:TM1040_2234 ABC transporter related YP_918855.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sit:TM1040_2233 ABC transporter related YP_918856.1 KEGG: bcn:Bcen_1215 esterase/lipase-like protein YP_918857.1 KEGG: sil:SPO0085 hypothetical protein YP_918858.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein; KEGG: rpb:RPB_1268 ATPase, E1-E2 type YP_918859.1 PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: bxe:Bxe_B0358 poly-beta-hydroxyalkanoate synthasePhbC YP_918860.1 PFAM: Surfeit locus 1 family protein; KEGG: sal:Sala_1504 surfeit locus 1 YP_918861.1 PFAM: cytochrome C oxidase subunit IV; KEGG: ret:RHE_PE00027 cytochrome o ubiquinol oxidase, subunit IV protein YP_918862.1 PFAM: cytochrome c oxidase, subunit III; KEGG: rpb:RPB_0240 cytochrome c oxidase, subunit III YP_918863.1 PFAM: cytochrome c oxidase, subunit I; KEGG: sal:Sala_1507 cytochrome-c oxidase YP_918864.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase, subunit II; COX aromatic rich domain protein; KEGG: bja:blr0149 cytochrome O ubiquinol oxidase subunit II YP_918865.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: bja:bll0148 MFS permease YP_918866.1 PFAM: CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase KEGG: rfr:Rfer_3783 cyclic nucleotide-binding domain (cNMP-BD) protein YP_918867.1 KEGG: rfr:Rfer_3780 hypothetical protein YP_918868.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rfr:Rfer_3779 periplasmic sensor signal transduction histidine kinase YP_918869.1 PFAM: response regulator receiver; KEGG: eba:ebA168 protein containing response regulator domain, but no DNA binding domain YP_918870.1 KEGG: rfr:Rfer_3777 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_918871.1 KEGG: rsp:RSP_1753 hypothetical protein YP_918872.1 TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: pfl:PFL_0325 agmatinase YP_918873.1 PFAM: protein of unknown function DUF1234; KEGG: rsp:RSP_3119 conserved hypothetical protein / esterase YP_918874.1 KEGG: rsp:RSP_3118 hypothetical protein YP_918875.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: mlo:mlr5227 NADH-dependent FMN reductase MsuE YP_918878.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: bja:blr8125 transcriptional regulatory protein YP_918881.1 KEGG: ret:RHE_PC00169 probable monooxygenase YP_918882.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sme:SMb20571 aliphatic sulfonate uptake ABC transporter permease YP_918883.1 KEGG: ret:RHE_PC00167 probable aliphatic sulphonate ABC transporter, substrate-binding protein YP_918884.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sme:SMb20569 ABC transporter ATP-binding protein YP_918885.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: neu:NE1071 probable sigma-70 factor, ECF subfamily YP_918886.1 PFAM: FecR protein; KEGG: neu:NE1070 transmembrane sensor YP_918887.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug; KEGG: nwi:Nwi_1732 TonB-dependent siderophore receptor YP_918888.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: nwi:Nwi_2042 secretion protein HlyD YP_918889.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: nwi:Nwi_2041 ABC transporter, ATPase subunit YP_918890.1 KEGG: ssn:SSO_1681 receptor