-- dump date   	20140619_231903
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
272843000001	superoxide dismutase; Provisional; Region: PRK10925
272843000002	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
272843000003	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
272843000004	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
272843000005	Malic enzyme, N-terminal domain; Region: malic; pfam00390
272843000006	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
272843000007	putative NAD(P) binding site [chemical binding]; other site
272843000008	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
272843000009	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
272843000010	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
272843000011	RNA binding surface [nucleotide binding]; other site
272843000012	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
272843000013	active site
272843000014	uracil binding [chemical binding]; other site
272843000015	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843000016	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
272843000017	putative substrate translocation pore; other site
272843000018	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
272843000019	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843000020	Walker A/P-loop; other site
272843000021	ATP binding site [chemical binding]; other site
272843000022	Q-loop/lid; other site
272843000023	ABC transporter signature motif; other site
272843000024	Walker B; other site
272843000025	D-loop; other site
272843000026	H-loop/switch region; other site
272843000027	heme exporter protein CcmB; Region: ccmB; TIGR01190
272843000028	heme exporter protein CcmC; Region: ccmC; TIGR01191
272843000029	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
272843000030	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
272843000031	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
272843000032	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
272843000033	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
272843000034	catalytic residues [active]
272843000035	central insert; other site
272843000036	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
272843000037	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
272843000038	cytochrome c-type biogenesis protein CcmI; Region: cytochro_ccmI; TIGR03142
272843000039	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
272843000040	TPR motif; other site
272843000041	binding surface
272843000042	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
272843000043	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
272843000044	putative metal binding site [ion binding]; other site
272843000045	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
272843000046	DNA replication initiation factor; Validated; Region: PRK06893
272843000047	uracil-xanthine permease; Region: ncs2; TIGR00801
272843000048	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843000049	active site
272843000050	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
272843000051	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
272843000052	active site
272843000053	substrate binding site [chemical binding]; other site
272843000054	cosubstrate binding site; other site
272843000055	catalytic site [active]
272843000056	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
272843000057	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
272843000058	dimerization interface [polypeptide binding]; other site
272843000059	putative ATP binding site [chemical binding]; other site
272843000060	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
272843000061	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit [Inorganic ion transport and metabolism]; Region: NrfA; COG3303
272843000062	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
272843000063	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
272843000064	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
272843000065	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
272843000066	cytochrome c nitrate reductase biogenesis protein NrfE; Region: cyt_nit_nrfE; TIGR03145
272843000067	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
272843000068	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
272843000069	catalytic residues [active]
272843000070	central insert; other site
272843000071	cytochrome c nitrite reductase, accessory protein NrfF; Region: cyt_nit_nrfF; TIGR03147
272843000072	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
272843000073	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
272843000074	binding surface
272843000075	TPR motif; other site
272843000076	Predicted flavoproteins [General function prediction only]; Region: COG2081
272843000077	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
272843000078	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
272843000079	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
272843000080	tetramer interface [polypeptide binding]; other site
272843000081	heme binding pocket [chemical binding]; other site
272843000082	NADPH binding site [chemical binding]; other site
272843000083	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
272843000084	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
272843000085	Coenzyme A binding pocket [chemical binding]; other site
272843000086	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
272843000087	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
272843000088	putative active site [active]
272843000089	putative PHP Thumb interface [polypeptide binding]; other site
272843000090	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
272843000091	generic binding surface II; other site
272843000092	generic binding surface I; other site
272843000093	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
272843000094	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
272843000095	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
272843000096	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
272843000097	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
272843000098	serine transporter; Region: stp; TIGR00814
272843000099	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
272843000100	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
272843000101	putative active site [active]
272843000102	putative dimer interface [polypeptide binding]; other site
272843000103	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
272843000104	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
272843000105	N-terminal plug; other site
272843000106	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
272843000107	ligand-binding site [chemical binding]; other site
272843000108	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
272843000109	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
272843000110	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
272843000111	Putative heme iron utilization protein [Inorganic ion transport and metabolism]; Region: HugZ; COG0748
272843000112	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
272843000113	glutamate dehydrogenase; Provisional; Region: PRK09414
272843000114	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
272843000115	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
272843000116	NAD(P) binding site [chemical binding]; other site
272843000117	hypothetical protein; Provisional; Region: PRK11111
272843000118	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
272843000119	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
272843000120	substrate binding pocket [chemical binding]; other site
272843000121	membrane-bound complex binding site; other site
272843000122	hinge residues; other site
272843000123	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
272843000124	N-acetyl-D-glucosamine binding site [chemical binding]; other site
272843000125	catalytic residue [active]
272843000126	disulfide bond formation protein B; Provisional; Region: PRK01749
272843000127	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
272843000128	fatty acid metabolism regulator; Provisional; Region: PRK04984
272843000129	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
272843000130	DNA-binding site [nucleotide binding]; DNA binding site
272843000131	FadR C-terminal domain; Region: FadR_C; pfam07840
272843000132	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
272843000133	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
272843000134	Walker A/P-loop; other site
272843000135	ATP binding site [chemical binding]; other site
272843000136	Q-loop/lid; other site
272843000137	ABC transporter signature motif; other site
272843000138	Walker B; other site
272843000139	D-loop; other site
272843000140	H-loop/switch region; other site
272843000141	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
272843000142	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843000143	dimer interface [polypeptide binding]; other site
272843000144	conserved gate region; other site
272843000145	putative PBP binding loops; other site
272843000146	ABC-ATPase subunit interface; other site
272843000147	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843000148	dimer interface [polypeptide binding]; other site
272843000149	conserved gate region; other site
272843000150	putative PBP binding loops; other site
272843000151	ABC-ATPase subunit interface; other site
272843000152	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
272843000153	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
272843000154	aminotransferase AlaT; Validated; Region: PRK09265
272843000155	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
272843000156	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843000157	homodimer interface [polypeptide binding]; other site
272843000158	catalytic residue [active]
272843000159	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
272843000160	chorismate binding enzyme; Region: Chorismate_bind; cl10555
272843000161	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
272843000162	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
272843000163	dimer interface [polypeptide binding]; other site
272843000164	tetramer interface [polypeptide binding]; other site
272843000165	PYR/PP interface [polypeptide binding]; other site
272843000166	TPP binding site [chemical binding]; other site
272843000167	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
272843000168	TPP-binding site; other site
272843000169	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
272843000170	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
272843000171	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
272843000172	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
272843000173	haemagglutination activity domain; Region: Haemagg_act; pfam05860
272843000174	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
272843000175	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
272843000176	Yersinia/Haemophilus virulence surface antigen; Region: Peptidase_C58; pfam03543
272843000177	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
272843000178	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
272843000179	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
272843000180	haemagglutination activity domain; Region: Haemagg_act; pfam05860
272843000181	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
272843000182	Fic/DOC family; Region: Fic; pfam02661
272843000183	Fic/DOC family; Region: Fic; pfam02661
272843000184	Yersinia/Haemophilus virulence surface antigen; Region: Peptidase_C58; pfam03543
272843000185	GTPase Era; Reviewed; Region: era; PRK00089
272843000186	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
272843000187	G1 box; other site
272843000188	GTP/Mg2+ binding site [chemical binding]; other site
272843000189	Switch I region; other site
272843000190	G2 box; other site
272843000191	Switch II region; other site
272843000192	G3 box; other site
272843000193	G4 box; other site
272843000194	G5 box; other site
272843000195	KH domain; Region: KH_2; pfam07650
272843000196	ribonuclease III; Reviewed; Region: rnc; PRK00102
272843000197	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
272843000198	dimerization interface [polypeptide binding]; other site
272843000199	active site
272843000200	metal binding site [ion binding]; metal-binding site
272843000201	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
272843000202	dsRNA binding site [nucleotide binding]; other site
272843000203	signal peptidase I; Provisional; Region: PRK10861
272843000204	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
272843000205	Catalytic site [active]
272843000206	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
272843000207	GTP-binding protein LepA; Provisional; Region: PRK05433
272843000208	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
272843000209	G1 box; other site
272843000210	putative GEF interaction site [polypeptide binding]; other site
272843000211	GTP/Mg2+ binding site [chemical binding]; other site
272843000212	Switch I region; other site
272843000213	G2 box; other site
272843000214	G3 box; other site
272843000215	Switch II region; other site
272843000216	G4 box; other site
272843000217	G5 box; other site
272843000218	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
272843000219	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
272843000220	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
272843000221	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
272843000222	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
272843000223	ligand binding site [chemical binding]; other site
272843000224	active site
272843000225	UGI interface [polypeptide binding]; other site
272843000226	catalytic site [active]
272843000227	hypothetical protein; Validated; Region: PRK02101
272843000228	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
272843000229	Cation efflux family; Region: Cation_efflux; cl00316
272843000230	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
272843000231	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
272843000232	active site
272843000233	ADP/pyrophosphate binding site [chemical binding]; other site
272843000234	dimerization interface [polypeptide binding]; other site
272843000235	allosteric effector site; other site
272843000236	fructose-1,6-bisphosphate binding site; other site
272843000237	23S rRNA methyluridine methyltransferase; Reviewed; Region: rumB; PRK03522
272843000238	beta-hexosaminidase; Provisional; Region: PRK05337
272843000239	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
272843000240	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
272843000241	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
272843000242	putative dimer interface [polypeptide binding]; other site
272843000243	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
272843000244	nucleotide binding site/active site [active]
272843000245	HIT family signature motif; other site
272843000246	catalytic residue [active]
272843000247	formate transporter FocA; Region: formate_focA; TIGR04060
272843000248	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
272843000249	Pyruvate formate lyase 1; Region: PFL1; cd01678
272843000250	coenzyme A binding site [chemical binding]; other site
272843000251	active site
272843000252	catalytic residues [active]
272843000253	glycine loop; other site
272843000254	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
272843000255	Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: Triacylglycerol_lipase_like; cd01847
272843000256	active site
272843000257	oxyanion hole [active]
272843000258	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
272843000259	catalytic triad [active]
272843000260	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
272843000261	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
272843000262	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843000263	FeS/SAM binding site; other site
272843000264	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
272843000265	nucleoside/Zn binding site; other site
272843000266	dimer interface [polypeptide binding]; other site
272843000267	catalytic motif [active]
272843000268	thymidylate synthase; Reviewed; Region: thyA; PRK01827
272843000269	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
272843000270	dimerization interface [polypeptide binding]; other site
272843000271	active site
272843000272	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
272843000273	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
272843000274	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
272843000275	putative active site [active]
272843000276	Ap4A binding site [chemical binding]; other site
272843000277	nudix motif; other site
272843000278	putative metal binding site [ion binding]; other site
272843000279	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
272843000280	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
272843000281	amidase catalytic site [active]
272843000282	Zn binding residues [ion binding]; other site
272843000283	substrate binding site [chemical binding]; other site
272843000284	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
272843000285	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
272843000286	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
272843000287	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
272843000288	Walker A motif; other site
272843000289	ATP binding site [chemical binding]; other site
272843000290	Walker B motif; other site
272843000291	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
272843000292	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
272843000293	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
272843000294	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
272843000295	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
272843000296	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
272843000297	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
272843000298	CoA-binding site [chemical binding]; other site
272843000299	ATP-binding [chemical binding]; other site
272843000300	DNA gyrase inhibitor; Reviewed; Region: PRK00418
272843000301	Predicted acetyltransferase [General function prediction only]; Region: COG2388
272843000302	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
272843000303	amino acid carrier protein; Region: agcS; TIGR00835
272843000304	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
272843000305	30S subunit binding site; other site
272843000306	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
272843000307	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
272843000308	active site
272843000309	Int/Topo IB signature motif; other site
272843000310	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
272843000311	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
272843000312	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
272843000313	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
272843000314	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
272843000315	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
272843000316	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
272843000317	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
272843000318	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843000319	FeS/SAM binding site; other site
272843000320	elongation factor P; Validated; Region: PRK00529
272843000321	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
272843000322	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
272843000323	RNA binding site [nucleotide binding]; other site
272843000324	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
272843000325	RNA binding site [nucleotide binding]; other site
272843000326	Uncharacterized integral membrane protein [Function unknown]; Region: COG5413
272843000327	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
272843000328	putative active site [active]
272843000329	putative metal binding site [ion binding]; other site
272843000330	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
272843000331	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
272843000332	putative acyl-acceptor binding pocket; other site
272843000333	FtsI repressor; Provisional; Region: PRK10883
272843000334	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
272843000335	GTP-binding protein Der; Reviewed; Region: PRK00093
272843000336	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
272843000337	G1 box; other site
272843000338	GTP/Mg2+ binding site [chemical binding]; other site
272843000339	Switch I region; other site
272843000340	G2 box; other site
272843000341	Switch II region; other site
272843000342	G3 box; other site
272843000343	G4 box; other site
272843000344	G5 box; other site
272843000345	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
272843000346	G1 box; other site
272843000347	GTP/Mg2+ binding site [chemical binding]; other site
272843000348	Switch I region; other site
272843000349	G2 box; other site
272843000350	G3 box; other site
272843000351	Switch II region; other site
272843000352	G4 box; other site
272843000353	G5 box; other site
272843000354	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
272843000355	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
272843000356	active site
272843000357	catalytic site [active]
272843000358	substrate binding site [chemical binding]; other site
272843000359	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
272843000360	RNA/DNA hybrid binding site [nucleotide binding]; other site
272843000361	active site
272843000362	Uncharacterized conserved protein [Function unknown]; Region: COG1801
272843000363	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
272843000364	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
272843000365	catalytic residue [active]
272843000366	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
272843000367	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
272843000368	nucleotide binding site [chemical binding]; other site
272843000369	substrate binding site [chemical binding]; other site
272843000370	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
272843000371	dimer interface [polypeptide binding]; other site
272843000372	putative threonine allosteric regulatory site; other site
272843000373	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
272843000374	putative threonine allosteric regulatory site; other site
272843000375	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
272843000376	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
272843000377	homoserine kinase; Provisional; Region: PRK01212
272843000378	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
272843000379	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
272843000380	threonine synthase; Validated; Region: PRK09225
272843000381	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
272843000382	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
272843000383	catalytic residue [active]
272843000384	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
272843000385	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
272843000386	FtsH protease regulator HflK; Provisional; Region: PRK10930
272843000387	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
272843000388	FtsH protease regulator HflC; Provisional; Region: PRK11029
272843000389	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
272843000390	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3028
272843000391	peptidase PmbA; Provisional; Region: PRK11040
272843000392	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
272843000393	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843000394	active site
272843000395	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
272843000396	dimer interface [polypeptide binding]; other site
272843000397	active site
272843000398	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
272843000399	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843000400	Walker A/P-loop; other site
272843000401	ATP binding site [chemical binding]; other site
272843000402	Q-loop/lid; other site
272843000403	ABC transporter signature motif; other site
272843000404	Walker B; other site
272843000405	D-loop; other site
272843000406	H-loop/switch region; other site
272843000407	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
272843000408	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
272843000409	substrate binding pocket [chemical binding]; other site
272843000410	membrane-bound complex binding site; other site
272843000411	hinge residues; other site
272843000412	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
272843000413	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843000414	dimer interface [polypeptide binding]; other site
272843000415	conserved gate region; other site
272843000416	putative PBP binding loops; other site
272843000417	ABC-ATPase subunit interface; other site
272843000418	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843000419	dimer interface [polypeptide binding]; other site
272843000420	conserved gate region; other site
272843000421	putative PBP binding loops; other site
272843000422	ABC-ATPase subunit interface; other site
272843000423	Uncharacterized protein family UPF0547; Region: UPF0547; pfam10571
272843000424	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
272843000425	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
272843000426	Walker A/P-loop; other site
272843000427	ATP binding site [chemical binding]; other site
272843000428	Q-loop/lid; other site
272843000429	ABC transporter signature motif; other site
272843000430	Walker B; other site
272843000431	D-loop; other site
272843000432	H-loop/switch region; other site
272843000433	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
272843000434	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
272843000435	ABC-ATPase subunit  interface; other site
272843000436	dimer interface [polypeptide binding]; other site
272843000437	putative PBP binding regions; other site
272843000438	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
272843000439	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
272843000440	ABC-ATPase subunit  interface; other site
272843000441	dimer interface [polypeptide binding]; other site
272843000442	putative PBP binding regions; other site
272843000443	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
272843000444	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
272843000445	siderophore binding site; other site
272843000446	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
272843000447	Carbon starvation protein CstA; Region: CstA; pfam02554
272843000448	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
272843000449	cell division protein MraZ; Reviewed; Region: PRK00326
272843000450	MraZ protein; Region: MraZ; pfam02381
272843000451	MraZ protein; Region: MraZ; pfam02381
272843000452	MraW methylase family; Region: Methyltransf_5; pfam01795
272843000453	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
272843000454	Cell division protein [Cell division and chromosome partitioning]; Region: FtsL; COG3116
272843000455	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
272843000456	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
272843000457	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
272843000458	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
272843000459	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
272843000460	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
272843000461	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
272843000462	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
272843000463	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
272843000464	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
272843000465	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
272843000466	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
272843000467	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
272843000468	Mg++ binding site [ion binding]; other site
272843000469	putative catalytic motif [active]
272843000470	putative substrate binding site [chemical binding]; other site
272843000471	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
272843000472	Putative NAD(P)-binding; Region: NAD_binding_7; cl17660
272843000473	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
272843000474	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
272843000475	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
272843000476	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
272843000477	active site
272843000478	homodimer interface [polypeptide binding]; other site
272843000479	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
272843000480	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
272843000481	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
272843000482	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
272843000483	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
272843000484	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
272843000485	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
272843000486	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
272843000487	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
272843000488	Cell division protein FtsQ; Region: FtsQ; pfam03799
272843000489	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
272843000490	Cell division protein FtsA; Region: FtsA; smart00842
272843000491	Cell division protein FtsA; Region: FtsA; pfam14450
272843000492	cell division protein FtsZ; Validated; Region: PRK09330
272843000493	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
272843000494	nucleotide binding site [chemical binding]; other site
272843000495	SulA interaction site; other site
272843000496	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
272843000497	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
272843000498	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
272843000499	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
272843000500	dimer interface [polypeptide binding]; other site
272843000501	active site
272843000502	metal binding site [ion binding]; metal-binding site
272843000503	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
272843000504	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
272843000505	Prephenate dehydratase; Region: PDT; pfam00800
272843000506	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
272843000507	putative L-Phe binding site [chemical binding]; other site
272843000508	transcriptional repressor RbsR; Provisional; Region: PRK10423
272843000509	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
272843000510	DNA binding site [nucleotide binding]
272843000511	domain linker motif; other site
272843000512	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
272843000513	dimerization interface [polypeptide binding]; other site
272843000514	ligand binding site [chemical binding]; other site
272843000515	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
272843000516	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
272843000517	substrate binding site [chemical binding]; other site
272843000518	dimer interface [polypeptide binding]; other site
272843000519	ATP binding site [chemical binding]; other site
272843000520	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
272843000521	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
272843000522	ligand binding site [chemical binding]; other site
272843000523	dimerization interface [polypeptide binding]; other site
272843000524	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
272843000525	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
272843000526	TM-ABC transporter signature motif; other site
272843000527	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
272843000528	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
272843000529	Walker A/P-loop; other site
272843000530	ATP binding site [chemical binding]; other site
272843000531	Q-loop/lid; other site
272843000532	ABC transporter signature motif; other site
272843000533	Walker B; other site
272843000534	D-loop; other site
272843000535	H-loop/switch region; other site
272843000536	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
272843000537	D-ribose pyranase; Provisional; Region: PRK11797
272843000538	Excalibur calcium-binding domain; Region: Excalibur; pfam05901
272843000539	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
272843000540	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
272843000541	PhnA protein; Region: PhnA; pfam03831
272843000542	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
272843000543	allantoate amidohydrolase; Reviewed; Region: PRK09290
272843000544	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
272843000545	active site
272843000546	metal binding site [ion binding]; metal-binding site
272843000547	dimer interface [polypeptide binding]; other site
272843000548	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
272843000549	dimer interface [polypeptide binding]; other site
272843000550	FMN binding site [chemical binding]; other site
272843000551	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
272843000552	GTP-binding protein YchF; Reviewed; Region: PRK09601
272843000553	YchF GTPase; Region: YchF; cd01900
272843000554	G1 box; other site
272843000555	GTP/Mg2+ binding site [chemical binding]; other site
272843000556	Switch I region; other site
272843000557	G2 box; other site
272843000558	Switch II region; other site
272843000559	G3 box; other site
272843000560	G4 box; other site
272843000561	G5 box; other site
272843000562	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
272843000563	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
272843000564	putative active site [active]
272843000565	catalytic residue [active]
272843000566	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
272843000567	putative coenzyme Q binding site [chemical binding]; other site
272843000568	hypothetical protein; Validated; Region: PRK01777
272843000569	Uncharacterized conserved protein [Function unknown]; Region: COG2850
272843000570	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
272843000571	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
272843000572	generic binding surface II; other site
272843000573	generic binding surface I; other site
272843000574	Predicted P-loop-containing kinase [General function prediction only]; Region: COG1660
272843000575	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
272843000576	active site
272843000577	phosphorylation site [posttranslational modification]
272843000578	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
272843000579	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
272843000580	Walker A/P-loop; other site
272843000581	ATP binding site [chemical binding]; other site
272843000582	Q-loop/lid; other site
272843000583	ABC transporter signature motif; other site
272843000584	Walker B; other site
272843000585	D-loop; other site
272843000586	H-loop/switch region; other site
272843000587	OstA-like protein; Region: OstA; cl00844
272843000588	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
272843000589	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117
272843000590	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
272843000591	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
272843000592	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
272843000593	Walker A/P-loop; other site
272843000594	ATP binding site [chemical binding]; other site
272843000595	Q-loop/lid; other site
272843000596	ABC transporter signature motif; other site
272843000597	Walker B; other site
272843000598	D-loop; other site
272843000599	H-loop/switch region; other site
272843000600	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
272843000601	conserved hypothetical integral membrane protein; Region: TIGR00056
272843000602	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
272843000603	mce related protein; Region: MCE; pfam02470
272843000604	ABC-type transport system involved in resistance to organic solvents, auxiliary component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2D; COG2854
272843000605	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
272843000606	anti sigma factor interaction site; other site
272843000607	regulatory phosphorylation site [posttranslational modification]; other site
272843000608	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
272843000609	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
272843000610	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
272843000611	hinge; other site
272843000612	active site
272843000613	exoribonuclease II; Provisional; Region: PRK05054
272843000614	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
272843000615	RNB domain; Region: RNB; pfam00773
272843000616	S1 RNA binding domain; Region: S1; pfam00575
272843000617	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
272843000618	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
272843000619	NAD binding site [chemical binding]; other site
272843000620	homotetramer interface [polypeptide binding]; other site
272843000621	homodimer interface [polypeptide binding]; other site
272843000622	substrate binding site [chemical binding]; other site
272843000623	active site
272843000624	Uncharacterized conserved protein [Function unknown]; Region: COG0327
272843000625	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
272843000626	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
272843000627	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843000628	FeS/SAM binding site; other site
272843000629	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
272843000630	active site
272843000631	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
272843000632	Ligand Binding Site [chemical binding]; other site
272843000633	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
272843000634	ligand binding site; other site
272843000635	tetramer interface; other site
272843000636	Sialyltransferase PMO188; Region: PM0188; pfam11477
272843000637	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
272843000638	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
272843000639	dimer interface [polypeptide binding]; other site
272843000640	putative anticodon binding site; other site
272843000641	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
272843000642	motif 1; other site
272843000643	active site
272843000644	motif 2; other site
272843000645	motif 3; other site
272843000646	This domain is found in peptide chain release factors; Region: PCRF; smart00937
272843000647	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
272843000648	RF-1 domain; Region: RF-1; pfam00472
272843000649	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
272843000650	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
272843000651	dimerization domain [polypeptide binding]; other site
272843000652	dimer interface [polypeptide binding]; other site
272843000653	catalytic residues [active]
272843000654	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
272843000655	DHH family; Region: DHH; pfam01368
272843000656	DHHA1 domain; Region: DHHA1; pfam02272
272843000657	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
272843000658	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
272843000659	catalytic residues [active]
272843000660	alpha helical domain; other site
272843000661	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
272843000662	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
272843000663	multifunctional aminopeptidase A; Provisional; Region: PRK00913
272843000664	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
272843000665	interface (dimer of trimers) [polypeptide binding]; other site
272843000666	Substrate-binding/catalytic site; other site
272843000667	Zn-binding sites [ion binding]; other site
272843000668	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
272843000669	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
272843000670	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
272843000671	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
272843000672	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
272843000673	Iron-sulfur protein interface; other site
272843000674	proximal quinone binding site [chemical binding]; other site
272843000675	C-subunit interface; other site
272843000676	distal quinone binding site; other site
272843000677	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
272843000678	D-subunit interface [polypeptide binding]; other site
272843000679	Iron-sulfur protein interface; other site
272843000680	proximal quinone binding site [chemical binding]; other site
272843000681	distal quinone binding site [chemical binding]; other site
272843000682	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
272843000683	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
272843000684	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
272843000685	L-aspartate oxidase; Provisional; Region: PRK06175
272843000686	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
272843000687	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
272843000688	poxB regulator PoxA; Provisional; Region: PRK09350
272843000689	motif 1; other site
272843000690	dimer interface [polypeptide binding]; other site
272843000691	active site
272843000692	motif 2; other site
272843000693	motif 3; other site
272843000694	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
272843000695	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
272843000696	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
272843000697	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
272843000698	substrate binding site [chemical binding]; other site
272843000699	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
272843000700	substrate binding site [chemical binding]; other site
272843000701	ligand binding site [chemical binding]; other site
272843000702	hypothetical protein; Validated; Region: PRK00153
272843000703	recombination protein RecR; Reviewed; Region: recR; PRK00076
272843000704	RecR protein; Region: RecR; pfam02132
272843000705	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
272843000706	putative active site [active]
272843000707	putative metal-binding site [ion binding]; other site
272843000708	tetramer interface [polypeptide binding]; other site
272843000709	DNA topoisomerase III; Provisional; Region: PRK07726
272843000710	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
272843000711	active site
272843000712	putative interdomain interaction site [polypeptide binding]; other site
272843000713	putative metal-binding site [ion binding]; other site
272843000714	putative nucleotide binding site [chemical binding]; other site
272843000715	Bacterial DNA topoisomeraes I ATP-binding domain; Region: TOP1Bc; smart00436
272843000716	domain I; other site
272843000717	phosphate binding site [ion binding]; other site
272843000718	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
272843000719	domain II; other site
272843000720	domain III; other site
272843000721	nucleotide binding site [chemical binding]; other site
272843000722	DNA binding groove [nucleotide binding]
272843000723	catalytic site [active]
272843000724	domain IV; other site
272843000725	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
272843000726	RNA polymerase sigma factor; Provisional; Region: PRK12530
272843000727	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
272843000728	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
272843000729	DNA binding residues [nucleotide binding]
272843000730	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3219
272843000731	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3220
272843000732	Uncharacterized low-complexity protein [Function unknown]; Region: COG3767
272843000733	Predicted membrane protein [Function unknown]; Region: COG2259
272843000734	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
272843000735	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843000736	active site
272843000737	phosphorylation site [posttranslational modification]
272843000738	intermolecular recognition site; other site
272843000739	dimerization interface [polypeptide binding]; other site
272843000740	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
272843000741	DNA binding site [nucleotide binding]
272843000742	sensor protein QseC; Provisional; Region: PRK10337
272843000743	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
272843000744	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
272843000745	dimer interface [polypeptide binding]; other site
272843000746	phosphorylation site [posttranslational modification]
272843000747	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843000748	ATP binding site [chemical binding]; other site
272843000749	Mg2+ binding site [ion binding]; other site
272843000750	G-X-G motif; other site
272843000751	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
272843000752	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
272843000753	SmpB-tmRNA interface; other site
272843000754	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
272843000755	two-component response regulator; Provisional; Region: PRK11173
272843000756	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843000757	active site
272843000758	phosphorylation site [posttranslational modification]
272843000759	intermolecular recognition site; other site
272843000760	dimerization interface [polypeptide binding]; other site
272843000761	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
272843000762	DNA binding site [nucleotide binding]
272843000763	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
272843000764	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
272843000765	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
272843000766	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
272843000767	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
272843000768	DsbD alpha interface [polypeptide binding]; other site
272843000769	catalytic residues [active]
272843000770	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
272843000771	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
272843000772	purine monophosphate binding site [chemical binding]; other site
272843000773	dimer interface [polypeptide binding]; other site
272843000774	putative catalytic residues [active]
272843000775	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
272843000776	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
272843000777	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
272843000778	Sulfatase; Region: Sulfatase; pfam00884
272843000779	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
272843000780	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
272843000781	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
272843000782	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
272843000783	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
272843000784	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
272843000785	dimer interface [polypeptide binding]; other site
272843000786	active site
272843000787	glycine-pyridoxal phosphate binding site [chemical binding]; other site
272843000788	folate binding site [chemical binding]; other site
272843000789	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
272843000790	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
272843000791	Protein export membrane protein; Region: SecD_SecF; pfam02355
272843000792	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
272843000793	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
272843000794	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
272843000795	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
272843000796	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
272843000797	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
272843000798	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
272843000799	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
272843000800	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
272843000801	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843000802	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
272843000803	active site
272843000804	motif I; other site
272843000805	motif II; other site
272843000806	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
272843000807	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
272843000808	putative protease; Provisional; Region: PRK15452
272843000809	Peptidase family U32; Region: Peptidase_U32; pfam01136
272843000810	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
272843000811	FAD binding site [chemical binding]; other site
272843000812	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
272843000813	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
272843000814	peptide binding site [polypeptide binding]; other site
272843000815	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
272843000816	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843000817	dimer interface [polypeptide binding]; other site
272843000818	conserved gate region; other site
272843000819	putative PBP binding loops; other site
272843000820	ABC-ATPase subunit interface; other site
272843000821	dipeptide transporter; Provisional; Region: PRK10913
272843000822	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
272843000823	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843000824	dimer interface [polypeptide binding]; other site
272843000825	conserved gate region; other site
272843000826	putative PBP binding loops; other site
272843000827	ABC-ATPase subunit interface; other site
272843000828	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
272843000829	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
272843000830	Walker A/P-loop; other site
272843000831	ATP binding site [chemical binding]; other site
272843000832	Q-loop/lid; other site
272843000833	ABC transporter signature motif; other site
272843000834	Walker B; other site
272843000835	D-loop; other site
272843000836	H-loop/switch region; other site
272843000837	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
272843000838	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
272843000839	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
272843000840	Walker A/P-loop; other site
272843000841	ATP binding site [chemical binding]; other site
272843000842	Q-loop/lid; other site
272843000843	ABC transporter signature motif; other site
272843000844	Walker B; other site
272843000845	D-loop; other site
272843000846	H-loop/switch region; other site
272843000847	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
272843000848	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
272843000849	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
272843000850	ABC-ATPase subunit  interface; other site
272843000851	dimer interface [polypeptide binding]; other site
272843000852	putative PBP binding regions; other site
272843000853	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
272843000854	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
272843000855	putative peptidase; Provisional; Region: PRK11649
272843000856	Peptidase family M23; Region: Peptidase_M23; pfam01551
272843000857	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
272843000858	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
272843000859	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843000860	active site
272843000861	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
272843000862	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
272843000863	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
272843000864	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
272843000865	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
272843000866	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
272843000867	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
272843000868	active site
272843000869	NTP binding site [chemical binding]; other site
272843000870	metal binding triad [ion binding]; metal-binding site
272843000871	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
272843000872	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
272843000873	Zn2+ binding site [ion binding]; other site
272843000874	Mg2+ binding site [ion binding]; other site
272843000875	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
272843000876	Bacterial SH3 domain homologues; Region: SH3b; smart00287
272843000877	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
272843000878	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
272843000879	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
272843000880	Uncharacterized conserved protein [Function unknown]; Region: COG3025
272843000881	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
272843000882	putative active site [active]
272843000883	putative metal binding residues [ion binding]; other site
272843000884	signature motif; other site
272843000885	putative triphosphate binding site [ion binding]; other site
272843000886	DNA repair protein RadA; Provisional; Region: PRK11823
272843000887	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
272843000888	Walker A motif; other site
272843000889	ATP binding site [chemical binding]; other site
272843000890	Walker B motif; other site
272843000891	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
272843000892	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
272843000893	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
272843000894	putative DNA binding site [nucleotide binding]; other site
272843000895	dimerization interface [polypeptide binding]; other site
272843000896	putative Zn2+ binding site [ion binding]; other site
272843000897	AsnC family; Region: AsnC_trans_reg; pfam01037
272843000898	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
272843000899	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
272843000900	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
272843000901	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
272843000902	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
272843000903	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
272843000904	recombination factor protein RarA; Reviewed; Region: PRK13342
272843000905	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843000906	Walker A motif; other site
272843000907	ATP binding site [chemical binding]; other site
272843000908	Walker B motif; other site
272843000909	arginine finger; other site
272843000910	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
272843000911	seryl-tRNA synthetase; Provisional; Region: PRK05431
272843000912	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
272843000913	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
272843000914	dimer interface [polypeptide binding]; other site
272843000915	active site
272843000916	motif 1; other site
272843000917	motif 2; other site
272843000918	motif 3; other site
272843000919	cytidine deaminase; Provisional; Region: PRK09027
272843000920	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
272843000921	active site
272843000922	catalytic motif [active]
272843000923	Zn binding site [ion binding]; other site
272843000924	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
272843000925	active site
272843000926	catalytic motif [active]
272843000927	Zn binding site [ion binding]; other site
272843000928	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
272843000929	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
272843000930	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
272843000931	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
272843000932	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
272843000933	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843000934	dimer interface [polypeptide binding]; other site
272843000935	conserved gate region; other site
272843000936	ABC-ATPase subunit interface; other site
272843000937	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
272843000938	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843000939	dimer interface [polypeptide binding]; other site
272843000940	conserved gate region; other site
272843000941	putative PBP binding loops; other site
272843000942	ABC-ATPase subunit interface; other site
272843000943	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
272843000944	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
272843000945	Walker A/P-loop; other site
272843000946	ATP binding site [chemical binding]; other site
272843000947	Q-loop/lid; other site
272843000948	ABC transporter signature motif; other site
272843000949	Walker B; other site
272843000950	D-loop; other site
272843000951	H-loop/switch region; other site
272843000952	TOBE domain; Region: TOBE_2; pfam08402
272843000953	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
272843000954	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
272843000955	metal binding site [ion binding]; metal-binding site
272843000956	dimer interface [polypeptide binding]; other site
272843000957	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
272843000958	mce related protein; Region: MCE; pfam02470
272843000959	mce related protein; Region: MCE; pfam02470
272843000960	mce related protein; Region: MCE; pfam02470
272843000961	mce related protein; Region: MCE; pfam02470
272843000962	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
272843000963	Transmembrane protein 55A; Region: Tmemb_55A; pfam09788
272843000964	Paraquat-inducible protein A; Region: PqiA; pfam04403
272843000965	Paraquat-inducible protein A; Region: PqiA; pfam04403
272843000966	ProP expression regulator; Provisional; Region: PRK04950
272843000967	ProQ/FINO family; Region: ProQ; pfam04352
272843000968	carboxy-terminal protease; Provisional; Region: PRK11186
272843000969	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
272843000970	protein binding site [polypeptide binding]; other site
272843000971	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
272843000972	Catalytic dyad [active]
272843000973	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
272843000974	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
272843000975	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
272843000976	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
272843000977	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
272843000978	Bacterial protein of unknown function (DUF882); Region: Peptidase_M15_2; pfam05951
272843000979	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
272843000980	DctM-like transporters; Region: DctM; pfam06808
272843000981	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
272843000982	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
272843000983	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
272843000984	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
272843000985	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
272843000986	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
272843000987	dimer interface [polypeptide binding]; other site
272843000988	active site
272843000989	citrylCoA binding site [chemical binding]; other site
272843000990	NADH binding [chemical binding]; other site
272843000991	cationic pore residues; other site
272843000992	oxalacetate/citrate binding site [chemical binding]; other site
272843000993	coenzyme A binding site [chemical binding]; other site
272843000994	catalytic triad [active]
272843000995	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
272843000996	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
272843000997	TPP-binding site [chemical binding]; other site
272843000998	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
272843000999	dimer interface [polypeptide binding]; other site
272843001000	PYR/PP interface [polypeptide binding]; other site
272843001001	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
272843001002	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
272843001003	E3 interaction surface; other site
272843001004	lipoyl attachment site [posttranslational modification]; other site
272843001005	e3 binding domain; Region: E3_binding; pfam02817
272843001006	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
272843001007	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
272843001008	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
272843001009	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
272843001010	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
272843001011	CoA-ligase; Region: Ligase_CoA; pfam00549
272843001012	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
272843001013	CoA binding domain; Region: CoA_binding; smart00881
272843001014	CoA-ligase; Region: Ligase_CoA; pfam00549
272843001015	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843001016	AAA domain; Region: AAA_21; pfam13304
272843001017	Walker A/P-loop; other site
272843001018	ATP binding site [chemical binding]; other site
272843001019	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
272843001020	adenylate kinase; Reviewed; Region: adk; PRK00279
272843001021	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
272843001022	AMP-binding site [chemical binding]; other site
272843001023	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
272843001024	muropeptide transporter; Reviewed; Region: ampG; PRK11902
272843001025	AmpG-like permease; Region: 2A0125; TIGR00901
272843001026	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
272843001027	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
272843001028	NAD binding site [chemical binding]; other site
272843001029	homodimer interface [polypeptide binding]; other site
272843001030	active site
272843001031	substrate binding site [chemical binding]; other site
272843001032	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
272843001033	Isopentenyl diphosphate isomerase (BS_ypgA, MTH48 and related proteins) [Coenzyme transport and metabolism]; Region: idi; COG1304
272843001034	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
272843001035	phosphate binding site [ion binding]; other site
272843001036	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
272843001037	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
272843001038	Ligand Binding Site [chemical binding]; other site
272843001039	TilS substrate binding domain; Region: TilS; pfam09179
272843001040	TilS substrate C-terminal domain; Region: TilS_C; smart00977
272843001041	pyridoxamine kinase; Validated; Region: PRK05756
272843001042	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
272843001043	pyridoxal binding site [chemical binding]; other site
272843001044	dimer interface [polypeptide binding]; other site
272843001045	ATP binding site [chemical binding]; other site
272843001046	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
272843001047	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
272843001048	GMP synthase; Reviewed; Region: guaA; PRK00074
272843001049	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
272843001050	AMP/PPi binding site [chemical binding]; other site
272843001051	candidate oxyanion hole; other site
272843001052	catalytic triad [active]
272843001053	potential glutamine specificity residues [chemical binding]; other site
272843001054	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
272843001055	ATP Binding subdomain [chemical binding]; other site
272843001056	Ligand Binding sites [chemical binding]; other site
272843001057	Dimerization subdomain; other site
272843001058	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
272843001059	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
272843001060	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
272843001061	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
272843001062	active site
272843001063	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
272843001064	Biotin operon repressor [Transcription]; Region: BirA; COG1654
272843001065	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
272843001066	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
272843001067	Putative heme iron utilization protein [Inorganic ion transport and metabolism]; Region: HugX; COG3721
272843001068	Putative heme iron utilization protein [Inorganic ion transport and metabolism]; Region: HugZ; COG0748
272843001069	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
272843001070	TonB-dependent lactoferrin and transferrin receptors; Region: TonB-tbp-lbp; TIGR01776
272843001071	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843001072	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
272843001073	ligand-binding site [chemical binding]; other site
272843001074	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
272843001075	16S/18S rRNA binding site [nucleotide binding]; other site
272843001076	S13e-L30e interaction site [polypeptide binding]; other site
272843001077	25S rRNA binding site [nucleotide binding]; other site
272843001078	antiporter inner membrane protein; Provisional; Region: PRK11670
272843001079	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
272843001080	Walker A motif; other site
272843001081	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
272843001082	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
272843001083	active site
272843001084	HIGH motif; other site
272843001085	KMSKS motif; other site
272843001086	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
272843001087	tRNA binding surface [nucleotide binding]; other site
272843001088	anticodon binding site; other site
272843001089	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
272843001090	dimer interface [polypeptide binding]; other site
272843001091	putative tRNA-binding site [nucleotide binding]; other site
272843001092	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
272843001093	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
272843001094	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
272843001095	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
272843001096	putative RNA binding site [nucleotide binding]; other site
272843001097	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843001098	S-adenosylmethionine binding site [chemical binding]; other site
272843001099	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cd09675
272843001100	CRISPR/Cas system-associated RAMP superfamily protein Csy2; Region: Csy2_I-F; cd09676
272843001101	CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cd09677
272843001102	CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cd09674
272843001103	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-F; cd09718
272843001104	CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673
272843001105	CRISPR-associated helicase Cas3, subtype I-F/YPEST; Region: cas3_yersinia; TIGR02562
272843001106	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
272843001107	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
272843001108	dimer interface [polypeptide binding]; other site
272843001109	phosphorylation site [posttranslational modification]
272843001110	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843001111	ATP binding site [chemical binding]; other site
272843001112	Mg2+ binding site [ion binding]; other site
272843001113	G-X-G motif; other site
272843001114	Response regulator receiver domain; Region: Response_reg; pfam00072
272843001115	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843001116	active site
272843001117	phosphorylation site [posttranslational modification]
272843001118	intermolecular recognition site; other site
272843001119	dimerization interface [polypeptide binding]; other site
272843001120	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
272843001121	putative binding surface; other site
272843001122	active site
272843001123	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
272843001124	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
272843001125	active site
272843001126	dimerization interface [polypeptide binding]; other site
272843001127	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
272843001128	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
272843001129	iron-sulfur cluster assembly transcription factor IscR; Region: IscR; TIGR02010
272843001130	Rrf2 family protein; Region: rrf2_super; TIGR00738
272843001131	cysteine desulfurase; Provisional; Region: PRK14012
272843001132	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
272843001133	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
272843001134	catalytic residue [active]
272843001135	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
272843001136	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
272843001137	trimerization site [polypeptide binding]; other site
272843001138	active site
272843001139	iron-sulfur cluster assembly protein IscA; Region: IscA; TIGR02011
272843001140	co-chaperone HscB; Provisional; Region: hscB; PRK05014
272843001141	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
272843001142	HSP70 interaction site [polypeptide binding]; other site
272843001143	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
272843001144	chaperone protein HscA; Provisional; Region: hscA; PRK05183
272843001145	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
272843001146	nucleotide binding site [chemical binding]; other site
272843001147	putative NEF/HSP70 interaction site [polypeptide binding]; other site
272843001148	SBD interface [polypeptide binding]; other site
272843001149	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
272843001150	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
272843001151	catalytic loop [active]
272843001152	iron binding site [ion binding]; other site
272843001153	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
272843001154	Transglycosylase; Region: Transgly; cl17702
272843001155	Trp operon repressor; Provisional; Region: PRK01381
272843001156	lytic murein transglycosylase; Provisional; Region: PRK11619
272843001157	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
272843001158	N-acetyl-D-glucosamine binding site [chemical binding]; other site
272843001159	catalytic residue [active]
272843001160	YciI-like protein; Reviewed; Region: PRK11370
272843001161	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
272843001162	intracellular septation protein A; Reviewed; Region: PRK00259
272843001163	OmpW family; Region: OmpW; cl17427
272843001164	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
272843001165	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
272843001166	Walker A/P-loop; other site
272843001167	ATP binding site [chemical binding]; other site
272843001168	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
272843001169	Q-loop/lid; other site
272843001170	ABC transporter signature motif; other site
272843001171	Walker B; other site
272843001172	D-loop; other site
272843001173	H-loop/switch region; other site
272843001174	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
272843001175	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
272843001176	GrpE; Region: GrpE; pfam01025
272843001177	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
272843001178	dimer interface [polypeptide binding]; other site
272843001179	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
272843001180	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
272843001181	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
272843001182	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843001183	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843001184	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843001185	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843001186	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
272843001187	Uncharacterized conserved protein [Function unknown]; Region: COG4121
272843001188	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
272843001189	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
272843001190	dimer interface [polypeptide binding]; other site
272843001191	active site
272843001192	Methyltransferase domain; Region: Methyltransf_23; pfam13489
272843001193	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843001194	S-adenosylmethionine binding site [chemical binding]; other site
272843001195	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
272843001196	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
272843001197	Na binding site [ion binding]; other site
272843001198	ribonuclease G; Provisional; Region: PRK11712
272843001199	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
272843001200	homodimer interface [polypeptide binding]; other site
272843001201	oligonucleotide binding site [chemical binding]; other site
272843001202	protease TldD; Provisional; Region: tldD; PRK10735
272843001203	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
272843001204	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
272843001205	inhibitor-cofactor binding pocket; inhibition site
272843001206	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843001207	catalytic residue [active]
272843001208	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
272843001209	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
272843001210	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
272843001211	substrate binding pocket [chemical binding]; other site
272843001212	chain length determination region; other site
272843001213	substrate-Mg2+ binding site; other site
272843001214	catalytic residues [active]
272843001215	aspartate-rich region 1; other site
272843001216	active site lid residues [active]
272843001217	aspartate-rich region 2; other site
272843001218	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
272843001219	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
272843001220	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
272843001221	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
272843001222	EamA-like transporter family; Region: EamA; pfam00892
272843001223	EamA-like transporter family; Region: EamA; pfam00892
272843001224	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
272843001225	EamA-like transporter family; Region: EamA; pfam00892
272843001226	EamA-like transporter family; Region: EamA; pfam00892
272843001227	GTPase CgtA; Reviewed; Region: obgE; PRK12298
272843001228	GTP1/OBG; Region: GTP1_OBG; pfam01018
272843001229	Obg GTPase; Region: Obg; cd01898
272843001230	G1 box; other site
272843001231	GTP/Mg2+ binding site [chemical binding]; other site
272843001232	Switch I region; other site
272843001233	G2 box; other site
272843001234	G3 box; other site
272843001235	Switch II region; other site
272843001236	G4 box; other site
272843001237	G5 box; other site
272843001238	ferric uptake regulator; Provisional; Region: fur; PRK09462
272843001239	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
272843001240	metal binding site 2 [ion binding]; metal-binding site
272843001241	putative DNA binding helix; other site
272843001242	metal binding site 1 [ion binding]; metal-binding site
272843001243	dimer interface [polypeptide binding]; other site
272843001244	structural Zn2+ binding site [ion binding]; other site
272843001245	flavodoxin FldA; Validated; Region: PRK09267
272843001246	LexA regulated protein; Provisional; Region: PRK11675
272843001247	acyl-CoA esterase; Provisional; Region: PRK10673
272843001248	PGAP1-like protein; Region: PGAP1; pfam07819
272843001249	replication initiation regulator SeqA; Provisional; Region: PRK11187
272843001250	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
272843001251	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
272843001252	acyl-activating enzyme (AAE) consensus motif; other site
272843001253	putative AMP binding site [chemical binding]; other site
272843001254	putative active site [active]
272843001255	putative CoA binding site [chemical binding]; other site
272843001256	hypothetical protein; Provisional; Region: PRK11281
272843001257	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
272843001258	Mechanosensitive ion channel; Region: MS_channel; pfam00924
272843001259	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
272843001260	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
272843001261	Tetramer interface [polypeptide binding]; other site
272843001262	active site
272843001263	FMN-binding site [chemical binding]; other site
272843001264	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
272843001265	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
272843001266	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
272843001267	hypothetical protein; Provisional; Region: PRK10621
272843001268	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
272843001269	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
272843001270	putative acyl-acceptor binding pocket; other site
272843001271	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843001272	active site
272843001273	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
272843001274	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843001275	Walker A motif; other site
272843001276	ATP binding site [chemical binding]; other site
272843001277	Walker B motif; other site
272843001278	arginine finger; other site
272843001279	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
272843001280	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
272843001281	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
272843001282	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
272843001283	homotrimer interaction site [polypeptide binding]; other site
272843001284	putative active site [active]
272843001285	YwiC-like protein; Region: YwiC; pfam14256
272843001286	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
272843001287	Sel1-like repeats; Region: SEL1; smart00671
272843001288	Sel1 repeat; Region: Sel1; cl02723
272843001289	Sel1-like repeats; Region: SEL1; smart00671
272843001290	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
272843001291	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
272843001292	CAP-like domain; other site
272843001293	active site
272843001294	primary dimer interface [polypeptide binding]; other site
272843001295	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
272843001296	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
272843001297	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843001298	ATP binding site [chemical binding]; other site
272843001299	Mg2+ binding site [ion binding]; other site
272843001300	G-X-G motif; other site
272843001301	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
272843001302	anchoring element; other site
272843001303	dimer interface [polypeptide binding]; other site
272843001304	ATP binding site [chemical binding]; other site
272843001305	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
272843001306	active site
272843001307	putative metal-binding site [ion binding]; other site
272843001308	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
272843001309	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
272843001310	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
272843001311	dimer interface [polypeptide binding]; other site
272843001312	active site
272843001313	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
272843001314	catalytic residues [active]
272843001315	substrate binding site [chemical binding]; other site
272843001316	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
272843001317	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
272843001318	NAD(P) binding pocket [chemical binding]; other site
272843001319	BtpA family; Region: BtpA; cl00440
272843001320	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
272843001321	Methyltransferase domain; Region: Methyltransf_31; pfam13847
272843001322	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843001323	S-adenosylmethionine binding site [chemical binding]; other site
272843001324	Predicted regulatory domain of a methyltransferase [General function prediction only]; Region: COG4797
272843001325	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
272843001326	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
272843001327	metal binding triad; other site
272843001328	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
272843001329	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
272843001330	metal binding triad; other site
272843001331	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
272843001332	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
272843001333	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
272843001334	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
272843001335	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843001336	dimer interface [polypeptide binding]; other site
272843001337	conserved gate region; other site
272843001338	putative PBP binding loops; other site
272843001339	ABC-ATPase subunit interface; other site
272843001340	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843001341	dimer interface [polypeptide binding]; other site
272843001342	conserved gate region; other site
272843001343	putative PBP binding loops; other site
272843001344	ABC-ATPase subunit interface; other site
272843001345	ABC-type thiamine transport system, ATPase component [Coenzyme metabolism]; Region: ThiQ; COG3840
272843001346	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843001347	Walker A/P-loop; other site
272843001348	ATP binding site [chemical binding]; other site
272843001349	Q-loop/lid; other site
272843001350	ABC transporter signature motif; other site
272843001351	Walker B; other site
272843001352	D-loop; other site
272843001353	H-loop/switch region; other site
272843001354	biotin synthase; Region: bioB; TIGR00433
272843001355	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843001356	FeS/SAM binding site; other site
272843001357	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
272843001358	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
272843001359	Na2 binding site [ion binding]; other site
272843001360	putative substrate binding site 1 [chemical binding]; other site
272843001361	Na binding site 1 [ion binding]; other site
272843001362	putative substrate binding site 2 [chemical binding]; other site
272843001363	endonuclease III; Provisional; Region: PRK10702
272843001364	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
272843001365	minor groove reading motif; other site
272843001366	helix-hairpin-helix signature motif; other site
272843001367	substrate binding pocket [chemical binding]; other site
272843001368	active site
272843001369	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
272843001370	electron transport complex RsxE subunit; Provisional; Region: PRK12405
272843001371	electron transport complex protein RnfG; Validated; Region: PRK01908
272843001372	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
272843001373	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
272843001374	SLBB domain; Region: SLBB; pfam10531
272843001375	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
272843001376	electron transport complex protein RnfB; Provisional; Region: PRK05113
272843001377	Putative Fe-S cluster; Region: FeS; pfam04060
272843001378	4Fe-4S binding domain; Region: Fer4; pfam00037
272843001379	electron transport complex protein RsxA; Provisional; Region: PRK05151
272843001380	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
272843001381	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
272843001382	trimer interface [polypeptide binding]; other site
272843001383	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
272843001384	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
272843001385	trimer interface [polypeptide binding]; other site
272843001386	eyelet of channel; other site
272843001387	HemK family putative methylases; Region: hemK_fam; TIGR00536
272843001388	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843001389	S-adenosylmethionine binding site [chemical binding]; other site
272843001390	hypothetical protein; Provisional; Region: PRK04946
272843001391	Smr domain; Region: Smr; pfam01713
272843001392	TIGR01666 family membrane protein; Region: YCCS
272843001393	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
272843001394	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
272843001395	Predicted membrane protein [Function unknown]; Region: COG3304
272843001396	Domain of unknown function (DUF307); Region: DUF307; pfam03733
272843001397	Domain of unknown function (DUF307); Region: DUF307; pfam03733
272843001398	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
272843001399	active site
272843001400	dimer interfaces [polypeptide binding]; other site
272843001401	catalytic residues [active]
272843001402	hypothetical protein; Provisional; Region: PRK01904
272843001403	acylphosphatase; Provisional; Region: PRK14448
272843001404	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
272843001405	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
272843001406	ABC-ATPase subunit  interface; other site
272843001407	dimer interface [polypeptide binding]; other site
272843001408	putative PBP binding regions; other site
272843001409	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
272843001410	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
272843001411	ABC-ATPase subunit  interface; other site
272843001412	dimer interface [polypeptide binding]; other site
272843001413	putative PBP binding regions; other site
272843001414	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
272843001415	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
272843001416	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
272843001417	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
272843001418	metal binding site [ion binding]; metal-binding site
272843001419	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
272843001420	DsrC like protein; Region: DsrC; pfam04358
272843001421	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
272843001422	YccA-like proteins; Region: YccA_like; cd10433
272843001423	Transcriptional regulator [Transcription]; Region: LysR; COG0583
272843001424	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
272843001425	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
272843001426	dimerization interface [polypeptide binding]; other site
272843001427	ABC transporter transmembrane region; Region: ABC_membrane_3; pfam13748
272843001428	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
272843001429	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
272843001430	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
272843001431	Cytochrome b subunit of formate dehydrogenase [Energy production and conversion]; Region: FdnI; COG2864
272843001432	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
272843001433	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
272843001434	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
272843001435	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
272843001436	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
272843001437	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
272843001438	molybdopterin cofactor binding site; other site
272843001439	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
272843001440	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
272843001441	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
272843001442	Part of AAA domain; Region: AAA_19; pfam13245
272843001443	Family description; Region: UvrD_C_2; pfam13538
272843001444	replicative DNA helicase; Validated; Region: PRK06904
272843001445	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
272843001446	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
272843001447	Walker A motif; other site
272843001448	ATP binding site [chemical binding]; other site
272843001449	Walker B motif; other site
272843001450	DNA binding loops [nucleotide binding]
272843001451	alanine racemase; Reviewed; Region: alr; PRK00053
272843001452	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
272843001453	active site
272843001454	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
272843001455	substrate binding site [chemical binding]; other site
272843001456	catalytic residues [active]
272843001457	dimer interface [polypeptide binding]; other site
272843001458	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
272843001459	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
272843001460	active site
272843001461	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
272843001462	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
272843001463	active site
272843001464	dimer interface [polypeptide binding]; other site
272843001465	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
272843001466	dimer interface [polypeptide binding]; other site
272843001467	active site
272843001468	Predicted transcriptional regulator [Transcription]; Region: COG2932
272843001469	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
272843001470	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
272843001471	Catalytic site [active]
272843001472	Predicted transcriptional regulator [Transcription]; Region: Nlp; COG3423
272843001473	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
272843001474	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
272843001475	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
272843001476	THF binding site; other site
272843001477	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
272843001478	substrate binding site [chemical binding]; other site
272843001479	THF binding site; other site
272843001480	zinc-binding site [ion binding]; other site
272843001481	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
272843001482	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
272843001483	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
272843001484	putative dimerization interface [polypeptide binding]; other site
272843001485	AzlC protein; Region: AzlC; cl00570
272843001486	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
272843001487	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
272843001488	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
272843001489	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
272843001490	ABC transporter; Region: ABC_tran_2; pfam12848
272843001491	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
272843001492	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
272843001493	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
272843001494	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
272843001495	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
272843001496	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
272843001497	excinuclease ABC subunit B; Provisional; Region: PRK05298
272843001498	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
272843001499	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843001500	ATP-binding site [chemical binding]; other site
272843001501	ATP binding site [chemical binding]; other site
272843001502	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843001503	nucleotide binding region [chemical binding]; other site
272843001504	ATP-binding site [chemical binding]; other site
272843001505	Ultra-violet resistance protein B; Region: UvrB; pfam12344
272843001506	UvrB/uvrC motif; Region: UVR; pfam02151
272843001507	Bacterial transcriptional activator domain; Region: BTAD; pfam03704
272843001508	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
272843001509	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
272843001510	putative active site [active]
272843001511	heme pocket [chemical binding]; other site
272843001512	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
272843001513	dimer interface [polypeptide binding]; other site
272843001514	phosphorylation site [posttranslational modification]
272843001515	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843001516	ATP binding site [chemical binding]; other site
272843001517	Mg2+ binding site [ion binding]; other site
272843001518	G-X-G motif; other site
272843001519	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
272843001520	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843001521	active site
272843001522	phosphorylation site [posttranslational modification]
272843001523	intermolecular recognition site; other site
272843001524	dimerization interface [polypeptide binding]; other site
272843001525	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
272843001526	DNA binding site [nucleotide binding]
272843001527	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
272843001528	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
272843001529	Walker A/P-loop; other site
272843001530	ATP binding site [chemical binding]; other site
272843001531	Q-loop/lid; other site
272843001532	ABC transporter signature motif; other site
272843001533	Walker B; other site
272843001534	D-loop; other site
272843001535	H-loop/switch region; other site
272843001536	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
272843001537	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843001538	dimer interface [polypeptide binding]; other site
272843001539	conserved gate region; other site
272843001540	putative PBP binding loops; other site
272843001541	ABC-ATPase subunit interface; other site
272843001542	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
272843001543	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843001544	dimer interface [polypeptide binding]; other site
272843001545	conserved gate region; other site
272843001546	putative PBP binding loops; other site
272843001547	ABC-ATPase subunit interface; other site
272843001548	PBP superfamily domain; Region: PBP_like_2; cl17296
272843001549	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
272843001550	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843001551	S-adenosylmethionine binding site [chemical binding]; other site
272843001552	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
272843001553	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843001554	Walker A motif; other site
272843001555	ATP binding site [chemical binding]; other site
272843001556	Walker B motif; other site
272843001557	arginine finger; other site
272843001558	Peptidase family M41; Region: Peptidase_M41; pfam01434
272843001559	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
272843001560	dihydropteroate synthase; Region: DHPS; TIGR01496
272843001561	substrate binding pocket [chemical binding]; other site
272843001562	dimer interface [polypeptide binding]; other site
272843001563	inhibitor binding site; inhibition site
272843001564	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
272843001565	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
272843001566	active site
272843001567	substrate binding site [chemical binding]; other site
272843001568	metal binding site [ion binding]; metal-binding site
272843001569	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
272843001570	catalytic core [active]
272843001571	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
272843001572	Septum formation inhibitor [Cell division and chromosome partitioning]; Region: MinC; COG0850
272843001573	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
272843001574	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
272843001575	Pyrimidine dimer DNA glycosylase; Region: Pyr_excise; pfam03013
272843001576	Cytochrome c553 [Energy production and conversion]; Region: COG2863
272843001577	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
272843001578	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
272843001579	catalytic residues [active]
272843001580	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
272843001581	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
272843001582	Walker A/P-loop; other site
272843001583	ATP binding site [chemical binding]; other site
272843001584	Q-loop/lid; other site
272843001585	ABC transporter signature motif; other site
272843001586	Walker B; other site
272843001587	D-loop; other site
272843001588	H-loop/switch region; other site
272843001589	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
272843001590	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
272843001591	FtsX-like permease family; Region: FtsX; pfam02687
272843001592	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
272843001593	FtsX-like permease family; Region: FtsX; pfam02687
272843001594	Predicted membrane protein [Function unknown]; Region: COG4393
272843001595	Predicted membrane protein (DUF2318); Region: DUF2318; pfam10080
272843001596	Uncharacterized conserved protein [Function unknown]; Region: COG3350
272843001597	Uncharacterized protein probably involved in high-affinity Fe2+ transport [Inorganic ion transport and metabolism]; Region: Tpd; COG3470
272843001598	High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; Region: FTR1; COG0672
272843001599	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
272843001600	active site pocket [active]
272843001601	oxyanion hole [active]
272843001602	catalytic triad [active]
272843001603	active site nucleophile [active]
272843001604	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
272843001605	penicillin-binding protein 1B; Region: PBP_1b; TIGR02071
272843001606	Transglycosylase; Region: Transgly; pfam00912
272843001607	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
272843001608	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3112
272843001609	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
272843001610	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
272843001611	active site
272843001612	PII uridylyl-transferase; Provisional; Region: glnD; PRK01759
272843001613	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
272843001614	metal binding triad; other site
272843001615	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
272843001616	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
272843001617	Zn2+ binding site [ion binding]; other site
272843001618	Mg2+ binding site [ion binding]; other site
272843001619	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
272843001620	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
272843001621	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
272843001622	EamA-like transporter family; Region: EamA; pfam00892
272843001623	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
272843001624	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
272843001625	inhibitor-cofactor binding pocket; inhibition site
272843001626	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843001627	catalytic residue [active]
272843001628	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
272843001629	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
272843001630	Mg++ binding site [ion binding]; other site
272843001631	putative catalytic motif [active]
272843001632	substrate binding site [chemical binding]; other site
272843001633	Chain length determinant protein [Cell envelope biogenesis, outer membrane]; Region: WzzB; COG3765
272843001634	Predicted membrane protein [Function unknown]; Region: COG2431
272843001635	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
272843001636	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
272843001637	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
272843001638	putative active site [active]
272843001639	putative metal-binding site [ion binding]; other site
272843001640	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
272843001641	active site
272843001642	DNA polymerase IV; Validated; Region: PRK02406
272843001643	DNA binding site [nucleotide binding]
272843001644	heat shock protein HtpX; Provisional; Region: PRK05457
272843001645	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
272843001646	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
272843001647	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
272843001648	Walker A/P-loop; other site
272843001649	ATP binding site [chemical binding]; other site
272843001650	Q-loop/lid; other site
272843001651	ABC transporter signature motif; other site
272843001652	Walker B; other site
272843001653	D-loop; other site
272843001654	H-loop/switch region; other site
272843001655	inner membrane transport permease; Provisional; Region: PRK15066
272843001656	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
272843001657	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
272843001658	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
272843001659	TRAP-type uncharacterized transport system, fused permease components [General function prediction only]; Region: COG4666
272843001660	TRAP-type uncharacterized transport system, fused permease components [General function prediction only]; Region: COG4666
272843001661	Domain of unknown function (DUF3394); Region: DUF3394; pfam11874
272843001662	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
272843001663	Ligand Binding Site [chemical binding]; other site
272843001664	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
272843001665	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
272843001666	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
272843001667	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
272843001668	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
272843001669	Zn-ribbon-containing, possibly nucleic-acid-binding protein [General function prediction only]; Region: COG5595
272843001670	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
272843001671	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
272843001672	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
272843001673	probable active site [active]
272843001674	Uncharacterized protein family (UPF0181); Region: UPF0181; pfam03701
272843001675	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
272843001676	DNA-binding site [nucleotide binding]; DNA binding site
272843001677	RNA-binding motif; other site
272843001678	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
272843001679	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
272843001680	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
272843001681	active site 1 [active]
272843001682	dimer interface [polypeptide binding]; other site
272843001683	active site 2 [active]
272843001684	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
272843001685	putative deacylase active site [active]
272843001686	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK06901
272843001687	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
272843001688	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
272843001689	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
272843001690	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
272843001691	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
272843001692	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
272843001693	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
272843001694	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
272843001695	Uncharacterized conserved protein [Function unknown]; Region: COG1434
272843001696	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
272843001697	putative active site [active]
272843001698	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
272843001699	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
272843001700	Glycosyltransferase family 52; Region: Glyco_transf_52; pfam07922
272843001701	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
272843001702	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
272843001703	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
272843001704	active site
272843001705	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
272843001706	GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; Region: GT2_AmsE_like; cd04195
272843001707	lytic murein transglycosylase; Region: MltB_2; TIGR02283
272843001708	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
272843001709	N-acetyl-D-glucosamine binding site [chemical binding]; other site
272843001710	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
272843001711	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
272843001712	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
272843001713	Part of AAA domain; Region: AAA_19; pfam13245
272843001714	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
272843001715	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
272843001716	AAA domain; Region: AAA_30; pfam13604
272843001717	Family description; Region: UvrD_C_2; pfam13538
272843001718	Glutaredoxin 2 [Posttranslational modification, protein turnover, chaperones]; Region: GrxB; COG2999
272843001719	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
272843001720	C-terminal domain interface [polypeptide binding]; other site
272843001721	GSH binding site (G-site) [chemical binding]; other site
272843001722	catalytic residues [active]
272843001723	putative dimer interface [polypeptide binding]; other site
272843001724	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
272843001725	N-terminal domain interface [polypeptide binding]; other site
272843001726	Uncharacterized conserved protein [Function unknown]; Region: COG3422
272843001727	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
272843001728	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
272843001729	23S rRNA interface [nucleotide binding]; other site
272843001730	L3 interface [polypeptide binding]; other site
272843001731	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
272843001732	stringent starvation protein A; Provisional; Region: sspA; PRK09481
272843001733	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
272843001734	C-terminal domain interface [polypeptide binding]; other site
272843001735	putative GSH binding site (G-site) [chemical binding]; other site
272843001736	dimer interface [polypeptide binding]; other site
272843001737	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
272843001738	dimer interface [polypeptide binding]; other site
272843001739	N-terminal domain interface [polypeptide binding]; other site
272843001740	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
272843001741	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
272843001742	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843001743	active site
272843001744	motif I; other site
272843001745	motif II; other site
272843001746	KpsF/GutQ family protein; Region: kpsF; TIGR00393
272843001747	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
272843001748	putative active site [active]
272843001749	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
272843001750	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
272843001751	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
272843001752	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
272843001753	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
272843001754	active site
272843001755	HIGH motif; other site
272843001756	nucleotide binding site [chemical binding]; other site
272843001757	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
272843001758	KMSKS motif; other site
272843001759	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
272843001760	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
272843001761	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
272843001762	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
272843001763	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
272843001764	Coenzyme A binding pocket [chemical binding]; other site
272843001765	hypothetical protein; Provisional; Region: PRK06762
272843001766	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
272843001767	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
272843001768	TPP-binding site; other site
272843001769	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
272843001770	PYR/PP interface [polypeptide binding]; other site
272843001771	dimer interface [polypeptide binding]; other site
272843001772	TPP binding site [chemical binding]; other site
272843001773	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
272843001774	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
272843001775	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
272843001776	substrate binding pocket [chemical binding]; other site
272843001777	chain length determination region; other site
272843001778	substrate-Mg2+ binding site; other site
272843001779	catalytic residues [active]
272843001780	aspartate-rich region 1; other site
272843001781	active site lid residues [active]
272843001782	aspartate-rich region 2; other site
272843001783	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
272843001784	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
272843001785	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
272843001786	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
272843001787	Ligand Binding Site [chemical binding]; other site
272843001788	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
272843001789	active site residue [active]
272843001790	dsDNA-mimic protein; Reviewed; Region: PRK05094
272843001791	TMAO/DMSO reductase; Reviewed; Region: PRK05363
272843001792	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
272843001793	Moco binding site; other site
272843001794	metal coordination site [ion binding]; other site
272843001795	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
272843001796	hypothetical protein; Provisional; Region: PRK05170
272843001797	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
272843001798	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
272843001799	glycogen branching enzyme; Provisional; Region: PRK05402
272843001800	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
272843001801	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
272843001802	active site
272843001803	catalytic site [active]
272843001804	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
272843001805	Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Region: PulA; COG1523
272843001806	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
272843001807	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
272843001808	active site
272843001809	catalytic site [active]
272843001810	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
272843001811	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
272843001812	ligand binding site; other site
272843001813	oligomer interface; other site
272843001814	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
272843001815	N-terminal domain interface [polypeptide binding]; other site
272843001816	sulfate 1 binding site; other site
272843001817	glycogen synthase; Provisional; Region: glgA; PRK00654
272843001818	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
272843001819	ADP-binding pocket [chemical binding]; other site
272843001820	homodimer interface [polypeptide binding]; other site
272843001821	glycogen phosphorylase; Provisional; Region: PRK14986
272843001822	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
272843001823	homodimer interface [polypeptide binding]; other site
272843001824	active site pocket [active]
272843001825	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
272843001826	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
272843001827	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
272843001828	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
272843001829	DNA binding site [nucleotide binding]
272843001830	domain linker motif; other site
272843001831	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
272843001832	dimerization interface [polypeptide binding]; other site
272843001833	ligand binding site [chemical binding]; other site
272843001834	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
272843001835	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
272843001836	NAD(P) binding site [chemical binding]; other site
272843001837	active site
272843001838	arginine repressor; Provisional; Region: PRK05066
272843001839	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
272843001840	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
272843001841	malate dehydrogenase; Provisional; Region: PRK05086
272843001842	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
272843001843	NAD binding site [chemical binding]; other site
272843001844	dimerization interface [polypeptide binding]; other site
272843001845	Substrate binding site [chemical binding]; other site
272843001846	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
272843001847	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
272843001848	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
272843001849	active site
272843001850	HIGH motif; other site
272843001851	KMSK motif region; other site
272843001852	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
272843001853	tRNA binding surface [nucleotide binding]; other site
272843001854	anticodon binding site; other site
272843001855	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
272843001856	putative metal binding site [ion binding]; other site
272843001857	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
272843001858	peptide chain release factor 1; Validated; Region: prfA; PRK00591
272843001859	This domain is found in peptide chain release factors; Region: PCRF; smart00937
272843001860	RF-1 domain; Region: RF-1; pfam00472
272843001861	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
272843001862	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
272843001863	Uncharacterized conserved protein [Function unknown]; Region: COG2912
272843001864	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
272843001865	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
272843001866	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
272843001867	glycerate dehydrogenase; Provisional; Region: PRK06932
272843001868	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
272843001869	putative ligand binding site [chemical binding]; other site
272843001870	putative NAD binding site [chemical binding]; other site
272843001871	catalytic site [active]
272843001872	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
272843001873	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
272843001874	FtsX-like permease family; Region: FtsX; pfam02687
272843001875	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
272843001876	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
272843001877	Walker A/P-loop; other site
272843001878	ATP binding site [chemical binding]; other site
272843001879	Q-loop/lid; other site
272843001880	ABC transporter signature motif; other site
272843001881	Walker B; other site
272843001882	D-loop; other site
272843001883	H-loop/switch region; other site
272843001884	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
272843001885	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
272843001886	FtsX-like permease family; Region: FtsX; pfam02687
272843001887	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG0722
272843001888	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
272843001889	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
272843001890	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
272843001891	Na binding site [ion binding]; other site
272843001892	putative substrate binding site [chemical binding]; other site
272843001893	cytosine deaminase; Provisional; Region: PRK09230
272843001894	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
272843001895	active site
272843001896	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
272843001897	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
272843001898	homodimer interface [polypeptide binding]; other site
272843001899	substrate-cofactor binding pocket; other site
272843001900	catalytic residue [active]
272843001901	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
272843001902	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
272843001903	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
272843001904	dimerization interface [polypeptide binding]; other site
272843001905	substrate binding pocket [chemical binding]; other site
272843001906	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
272843001907	N-Utilization Substance G (NusG) N-terminal (NGN) domain Superfamily; Region: NGN; cl02766
272843001908	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
272843001909	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
272843001910	dinuclear metal binding motif [ion binding]; other site
272843001911	Acyl-CoA thioesterase [Lipid metabolism]; Region: TesB; COG1946
272843001912	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
272843001913	active site
272843001914	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
272843001915	catalytic triad [active]
272843001916	dimer interface [polypeptide binding]; other site
272843001917	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
272843001918	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
272843001919	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843001920	Walker A/P-loop; other site
272843001921	ATP binding site [chemical binding]; other site
272843001922	Q-loop/lid; other site
272843001923	ABC transporter signature motif; other site
272843001924	Walker B; other site
272843001925	D-loop; other site
272843001926	H-loop/switch region; other site
272843001927	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
272843001928	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
272843001929	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843001930	Walker A/P-loop; other site
272843001931	ATP binding site [chemical binding]; other site
272843001932	Q-loop/lid; other site
272843001933	ABC transporter signature motif; other site
272843001934	Walker B; other site
272843001935	D-loop; other site
272843001936	H-loop/switch region; other site
272843001937	thioredoxin reductase; Provisional; Region: PRK10262
272843001938	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
272843001939	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
272843001940	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
272843001941	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
272843001942	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
272843001943	active site clefts [active]
272843001944	zinc binding site [ion binding]; other site
272843001945	dimer interface [polypeptide binding]; other site
272843001946	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
272843001947	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
272843001948	N-terminal plug; other site
272843001949	ligand-binding site [chemical binding]; other site
272843001950	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
272843001951	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
272843001952	substrate binding site [chemical binding]; other site
272843001953	active site
272843001954	catalytic residues [active]
272843001955	heterodimer interface [polypeptide binding]; other site
272843001956	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
272843001957	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
272843001958	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843001959	catalytic residue [active]
272843001960	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
272843001961	malonic semialdehyde reductase; Provisional; Region: PRK10538
272843001962	putative NAD(P) binding site [chemical binding]; other site
272843001963	homotetramer interface [polypeptide binding]; other site
272843001964	homodimer interface [polypeptide binding]; other site
272843001965	active site
272843001966	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
272843001967	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
272843001968	active site
272843001969	ribulose/triose binding site [chemical binding]; other site
272843001970	phosphate binding site [ion binding]; other site
272843001971	substrate (anthranilate) binding pocket [chemical binding]; other site
272843001972	product (indole) binding pocket [chemical binding]; other site
272843001973	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
272843001974	active site
272843001975	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
272843001976	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
272843001977	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
272843001978	Membrane transport protein; Region: Mem_trans; cl09117
272843001979	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
272843001980	Glutamine amidotransferase class-I; Region: GATase; pfam00117
272843001981	glutamine binding [chemical binding]; other site
272843001982	catalytic triad [active]
272843001983	anthranilate synthase component I; Provisional; Region: PRK13564
272843001984	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
272843001985	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
272843001986	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
272843001987	putative inner membrane peptidase; Provisional; Region: PRK11778
272843001988	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
272843001989	tandem repeat interface [polypeptide binding]; other site
272843001990	oligomer interface [polypeptide binding]; other site
272843001991	active site residues [active]
272843001992	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
272843001993	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
272843001994	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
272843001995	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
272843001996	ligand binding site [chemical binding]; other site
272843001997	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3001
272843001998	Phosphotransferase enzyme family; Region: APH; pfam01636
272843001999	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
272843002000	Na binding site [ion binding]; other site
272843002001	bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: PRK11905
272843002002	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
272843002003	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
272843002004	Glutamate binding site [chemical binding]; other site
272843002005	NAD binding site [chemical binding]; other site
272843002006	catalytic residues [active]
272843002007	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
272843002008	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
272843002009	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
272843002010	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
272843002011	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
272843002012	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
272843002013	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
272843002014	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
272843002015	peptide binding site [polypeptide binding]; other site
272843002016	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
272843002017	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
272843002018	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
272843002019	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
272843002020	active site
272843002021	dimer interface [polypeptide binding]; other site
272843002022	motif 1; other site
272843002023	motif 2; other site
272843002024	motif 3; other site
272843002025	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
272843002026	anticodon binding site; other site
272843002027	Uncharacterized conserved protein [Function unknown]; Region: COG1479
272843002028	Protein of unknown function DUF262; Region: DUF262; pfam03235
272843002029	Uncharacterized conserved protein [Function unknown]; Region: COG1479
272843002030	Protein of unknown function DUF262; Region: DUF262; pfam03235
272843002031	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
272843002032	Predicted permeases [General function prediction only]; Region: COG0730
272843002033	putative transporter; Provisional; Region: PRK10484
272843002034	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
272843002035	Na binding site [ion binding]; other site
272843002036	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
272843002037	Sulfatase; Region: Sulfatase; cl17466
272843002038	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
272843002039	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
272843002040	ligand binding site [chemical binding]; other site
272843002041	flexible hinge region; other site
272843002042	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
272843002043	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843002044	FeS/SAM binding site; other site
272843002045	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
272843002046	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
272843002047	active site
272843002048	phosphate binding residues; other site
272843002049	catalytic residues [active]
272843002050	translation initiation factor IF-3; Region: infC; TIGR00168
272843002051	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
272843002052	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
272843002053	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
272843002054	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
272843002055	23S rRNA binding site [nucleotide binding]; other site
272843002056	L21 binding site [polypeptide binding]; other site
272843002057	L13 binding site [polypeptide binding]; other site
272843002058	methionine sulfoxide reductase A; Provisional; Region: PRK14054
272843002059	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
272843002060	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
272843002061	Ligand Binding Site [chemical binding]; other site
272843002062	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukF; COG3006
272843002063	condesin subunit E; Provisional; Region: PRK05256
272843002064	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
272843002065	P-loop containing region of AAA domain; Region: AAA_29; cl17516
272843002066	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
272843002067	exonuclease I; Provisional; Region: sbcB; PRK11779
272843002068	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
272843002069	active site
272843002070	catalytic site [active]
272843002071	substrate binding site [chemical binding]; other site
272843002072	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
272843002073	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
272843002074	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
272843002075	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
272843002076	active site
272843002077	interdomain interaction site; other site
272843002078	putative metal-binding site [ion binding]; other site
272843002079	nucleotide binding site [chemical binding]; other site
272843002080	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
272843002081	domain I; other site
272843002082	DNA binding groove [nucleotide binding]
272843002083	phosphate binding site [ion binding]; other site
272843002084	domain II; other site
272843002085	domain III; other site
272843002086	nucleotide binding site [chemical binding]; other site
272843002087	catalytic site [active]
272843002088	domain IV; other site
272843002089	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
272843002090	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
272843002091	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
272843002092	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
272843002093	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
272843002094	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
272843002095	active site
272843002096	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
272843002097	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
272843002098	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
272843002099	quinone interaction residues [chemical binding]; other site
272843002100	active site
272843002101	catalytic residues [active]
272843002102	FMN binding site [chemical binding]; other site
272843002103	substrate binding site [chemical binding]; other site
272843002104	aminopeptidase N; Provisional; Region: pepN; PRK14015
272843002105	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
272843002106	active site
272843002107	Zn binding site [ion binding]; other site
272843002108	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
272843002109	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) [Nucleotide transport and metabolism]; Region: PurK; COG0026
272843002110	CUT domain; Region: CUT; pfam02376
272843002111	ATP-grasp domain; Region: ATP-grasp; pfam02222
272843002112	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
272843002113	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
272843002114	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843002115	homodimer interface [polypeptide binding]; other site
272843002116	catalytic residue [active]
272843002117	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
272843002118	MoaE homodimer interface [polypeptide binding]; other site
272843002119	MoaD interaction [polypeptide binding]; other site
272843002120	active site residues [active]
272843002121	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
272843002122	MoaE interaction surface [polypeptide binding]; other site
272843002123	MoeB interaction surface [polypeptide binding]; other site
272843002124	thiocarboxylated glycine; other site
272843002125	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
272843002126	trimer interface [polypeptide binding]; other site
272843002127	dimer interface [polypeptide binding]; other site
272843002128	putative active site [active]
272843002129	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
272843002130	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843002131	FeS/SAM binding site; other site
272843002132	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
272843002133	Uncharacterized protein family UPF0052; Region: UPF0052; pfam01933
272843002134	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
272843002135	phosphate binding site [ion binding]; other site
272843002136	putative substrate binding pocket [chemical binding]; other site
272843002137	dimer interface [polypeptide binding]; other site
272843002138	NlpC/P60 family; Region: NLPC_P60; pfam00877
272843002139	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
272843002140	IHF dimer interface [polypeptide binding]; other site
272843002141	IHF - DNA interface [nucleotide binding]; other site
272843002142	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
272843002143	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
272843002144	putative tRNA-binding site [nucleotide binding]; other site
272843002145	B3/4 domain; Region: B3_4; pfam03483
272843002146	tRNA synthetase B5 domain; Region: B5; smart00874
272843002147	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
272843002148	dimer interface [polypeptide binding]; other site
272843002149	motif 1; other site
272843002150	motif 3; other site
272843002151	motif 2; other site
272843002152	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
272843002153	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
272843002154	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
272843002155	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
272843002156	dimer interface [polypeptide binding]; other site
272843002157	motif 1; other site
272843002158	active site
272843002159	motif 2; other site
272843002160	motif 3; other site
272843002161	Uncharacterized conserved protein [Function unknown]; Region: COG4283
272843002162	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
272843002163	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
272843002164	active site
272843002165	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
272843002166	catalytic core [active]
272843002167	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
272843002168	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
272843002169	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
272843002170	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
272843002171	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
272843002172	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
272843002173	dimerization interface 3.5A [polypeptide binding]; other site
272843002174	active site
272843002175	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
272843002176	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
272843002177	active site
272843002178	nucleophile elbow; other site
272843002179	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
272843002180	5S rRNA interface [nucleotide binding]; other site
272843002181	CTC domain interface [polypeptide binding]; other site
272843002182	L16 interface [polypeptide binding]; other site
272843002183	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
272843002184	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
272843002185	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
272843002186	AAA domain; Region: AAA_26; pfam13500
272843002187	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
272843002188	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
272843002189	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
272843002190	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
272843002191	putative dimer interface [polypeptide binding]; other site
272843002192	putative anticodon binding site; other site
272843002193	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
272843002194	homodimer interface [polypeptide binding]; other site
272843002195	motif 1; other site
272843002196	motif 2; other site
272843002197	active site
272843002198	motif 3; other site
272843002199	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell envelope biogenesis, outer membrane]; Region: PbpC; COG4953
272843002200	Transglycosylase; Region: Transgly; pfam00912
272843002201	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
272843002202	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
272843002203	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
272843002204	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
272843002205	putative SAM binding site [chemical binding]; other site
272843002206	putative homodimer interface [polypeptide binding]; other site
272843002207	LppC putative lipoprotein; Region: LppC; pfam04348
272843002208	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
272843002209	putative ligand binding site [chemical binding]; other site
272843002210	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
272843002211	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
272843002212	dimer interface [polypeptide binding]; other site
272843002213	active site
272843002214	outer membrane lipoprotein; Provisional; Region: PRK11023
272843002215	BON domain; Region: BON; pfam04972
272843002216	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
272843002217	Lumazine binding domain; Region: Lum_binding; pfam00677
272843002218	Lumazine binding domain; Region: Lum_binding; pfam00677
272843002219	multidrug efflux protein; Reviewed; Region: PRK01766
272843002220	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
272843002221	cation binding site [ion binding]; other site
272843002222	putative oxidoreductase; Provisional; Region: PRK11579
272843002223	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
272843002224	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
272843002225	pyruvate kinase; Provisional; Region: PRK05826
272843002226	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
272843002227	domain interfaces; other site
272843002228	active site
272843002229	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
272843002230	DNA-binding site [nucleotide binding]; DNA binding site
272843002231	RNA-binding motif; other site
272843002232	tellurite resistance protein TehB; Provisional; Region: PRK12335
272843002233	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
272843002234	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843002235	S-adenosylmethionine binding site [chemical binding]; other site
272843002236	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
272843002237	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
272843002238	trimer interface [polypeptide binding]; other site
272843002239	active site
272843002240	substrate binding site [chemical binding]; other site
272843002241	CoA binding site [chemical binding]; other site
272843002242	IgD-like repeat domain of mycobacterial L,D-transpeptidases; Region: LDT_IgD_like; cl17506
272843002243	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
272843002244	MG2 domain; Region: A2M_N; pfam01835
272843002245	Alpha-2-macroglobulin family; Region: A2M; pfam00207
272843002246	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
272843002247	surface patch; other site
272843002248	thioester region; other site
272843002249	specificity defining residues; other site
272843002250	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
272843002251	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
272843002252	The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413
272843002253	substrate binding site [chemical binding]; other site
272843002254	dimerization interface [polypeptide binding]; other site
272843002255	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
272843002256	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
272843002257	RNA binding surface [nucleotide binding]; other site
272843002258	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
272843002259	probable active site [active]
272843002260	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
272843002261	Neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: NanH; COG4409
272843002262	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
272843002263	catalytic site [active]
272843002264	Asp-box motif; other site
272843002265	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
272843002266	Chorismate mutase type II; Region: CM_2; cl00693
272843002267	prephenate dehydrogenase; Validated; Region: PRK08507
272843002268	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
272843002269	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
272843002270	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
272843002271	Ferritin-like domain; Region: Ferritin; pfam00210
272843002272	ferroxidase diiron center [ion binding]; other site
272843002273	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
272843002274	Ferritin-like domain; Region: Ferritin; pfam00210
272843002275	ferroxidase diiron center [ion binding]; other site
272843002276	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
272843002277	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
272843002278	ligand binding site [chemical binding]; other site
272843002279	flexible hinge region; other site
272843002280	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
272843002281	putative switch regulator; other site
272843002282	non-specific DNA interactions [nucleotide binding]; other site
272843002283	DNA binding site [nucleotide binding]
272843002284	sequence specific DNA binding site [nucleotide binding]; other site
272843002285	putative cAMP binding site [chemical binding]; other site
272843002286	universal stress protein UspE; Provisional; Region: PRK11175
272843002287	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
272843002288	Ligand Binding Site [chemical binding]; other site
272843002289	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
272843002290	Ligand Binding Site [chemical binding]; other site
272843002291	Soluble cytochrome b562 [Energy production and conversion]; Region: CybC; COG3783
272843002292	signal peptide peptidase SppA, 67K type; Region: SppA_67K; TIGR00705
272843002293	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
272843002294	tandem repeat interface [polypeptide binding]; other site
272843002295	oligomer interface [polypeptide binding]; other site
272843002296	active site residues [active]
272843002297	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
272843002298	tandem repeat interface [polypeptide binding]; other site
272843002299	oligomer interface [polypeptide binding]; other site
272843002300	active site residues [active]
272843002301	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
272843002302	putative FMN binding site [chemical binding]; other site
272843002303	RIO kinase family, catalytic domain. The RIO kinase catalytic domain family is part of a larger superfamily, that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs), aminoglycoside...; Region: RIO; cl17248
272843002304	ATP binding site [chemical binding]; other site
272843002305	fructokinase; Reviewed; Region: PRK09557
272843002306	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
272843002307	nucleotide binding site [chemical binding]; other site
272843002308	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
272843002309	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
272843002310	active site
272843002311	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
272843002312	dimerization interface [polypeptide binding]; other site
272843002313	active site
272843002314	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
272843002315	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
272843002316	peptide binding site [polypeptide binding]; other site
272843002317	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2832
272843002318	oligopeptidase A; Provisional; Region: PRK10911
272843002319	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
272843002320	active site
272843002321	Zn binding site [ion binding]; other site
272843002322	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
272843002323	MarR family; Region: MarR_2; cl17246
272843002324	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
272843002325	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
272843002326	nucleotide binding site [chemical binding]; other site
272843002327	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
272843002328	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
272843002329	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
272843002330	tRNA; other site
272843002331	putative tRNA binding site [nucleotide binding]; other site
272843002332	putative NADP binding site [chemical binding]; other site
272843002333	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
272843002334	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
272843002335	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843002336	uncharacterized domain; Region: TIGR00702
272843002337	YcaO-like family; Region: YcaO; pfam02624
272843002338	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
272843002339	Protein of unknown function (DUF1043); Region: DUF1043; pfam06295
272843002340	TIGR01619 family protein; Region: hyp_HI0040
272843002341	Family of unknown function (DUF695); Region: DUF695; pfam05117
272843002342	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
272843002343	putative catalytic site [active]
272843002344	putative phosphate binding site [ion binding]; other site
272843002345	active site
272843002346	metal binding site A [ion binding]; metal-binding site
272843002347	DNA binding site [nucleotide binding]
272843002348	putative AP binding site [nucleotide binding]; other site
272843002349	putative metal binding site B [ion binding]; other site
272843002350	acetyl-CoA synthetase; Provisional; Region: PRK00174
272843002351	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
272843002352	active site
272843002353	CoA binding site [chemical binding]; other site
272843002354	acyl-activating enzyme (AAE) consensus motif; other site
272843002355	AMP binding site [chemical binding]; other site
272843002356	acetate binding site [chemical binding]; other site
272843002357	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
272843002358	homodecamer interface [polypeptide binding]; other site
272843002359	GTP cyclohydrolase I; Provisional; Region: PLN03044
272843002360	active site
272843002361	putative catalytic site residues [active]
272843002362	zinc binding site [ion binding]; other site
272843002363	GTP-CH-I/GFRP interaction surface; other site
272843002364	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
272843002365	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
272843002366	dimer interface [polypeptide binding]; other site
272843002367	putative functional site; other site
272843002368	putative MPT binding site; other site
272843002369	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
272843002370	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
272843002371	ATP binding site [chemical binding]; other site
272843002372	substrate interface [chemical binding]; other site
272843002373	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_c; cd10311
272843002374	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
272843002375	putative active site [active]
272843002376	catalytic site [active]
272843002377	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843002378	ATP binding site [chemical binding]; other site
272843002379	putative Mg++ binding site [ion binding]; other site
272843002380	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843002381	nucleotide binding region [chemical binding]; other site
272843002382	ATP-binding site [chemical binding]; other site
272843002383	Domain of unknown function (DUF4391); Region: DUF4391; pfam14335
272843002384	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
272843002385	DNA methylase; Region: N6_N4_Mtase; pfam01555
272843002386	DNA methylase; Region: N6_N4_Mtase; cl17433
272843002387	Restriction endonuclease [Defense mechanisms]; Region: COG3587
272843002388	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
272843002389	ATP binding site [chemical binding]; other site
272843002390	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
272843002391	Flavoprotein; Region: Flavoprotein; pfam02441
272843002392	amidophosphoribosyltransferase; Provisional; Region: PRK09246
272843002393	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
272843002394	active site
272843002395	tetramer interface [polypeptide binding]; other site
272843002396	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843002397	active site
272843002398	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
272843002399	Colicin V production protein; Region: Colicin_V; cl00567
272843002400	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3092
272843002401	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
272843002402	propionate/acetate kinase; Provisional; Region: PRK12379
272843002403	phosphate acetyltransferase; Reviewed; Region: PRK05632
272843002404	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
272843002405	DRTGG domain; Region: DRTGG; pfam07085
272843002406	phosphate acetyltransferase; Region: pta; TIGR00651
272843002407	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
272843002408	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
272843002409	catalytic site [active]
272843002410	putative active site [active]
272843002411	putative substrate binding site [chemical binding]; other site
272843002412	HRDC domain; Region: HRDC; pfam00570
272843002413	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
272843002414	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
272843002415	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
272843002416	acyl-activating enzyme (AAE) consensus motif; other site
272843002417	putative AMP binding site [chemical binding]; other site
272843002418	putative active site [active]
272843002419	putative CoA binding site [chemical binding]; other site
272843002420	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
272843002421	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
272843002422	Glycoprotease family; Region: Peptidase_M22; pfam00814
272843002423	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
272843002424	DEAD_2; Region: DEAD_2; pfam06733
272843002425	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
272843002426	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
272843002427	active site
272843002428	phosphate binding residues; other site
272843002429	catalytic residues [active]
272843002430	Predicted permeases [General function prediction only]; Region: COG0679
272843002431	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
272843002432	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
272843002433	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
272843002434	trimer interface [polypeptide binding]; other site
272843002435	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
272843002436	trimer interface [polypeptide binding]; other site
272843002437	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
272843002438	trimer interface [polypeptide binding]; other site
272843002439	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
272843002440	trimer interface [polypeptide binding]; other site
272843002441	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
272843002442	trimer interface [polypeptide binding]; other site
272843002443	Haemagglutinin; Region: HIM; pfam05662
272843002444	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
272843002445	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
272843002446	YadA-like C-terminal region; Region: YadA; pfam03895
272843002447	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
272843002448	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
272843002449	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
272843002450	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
272843002451	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
272843002452	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
272843002453	ATP cone domain; Region: ATP-cone; pfam03477
272843002454	Class I ribonucleotide reductase; Region: RNR_I; cd01679
272843002455	active site
272843002456	dimer interface [polypeptide binding]; other site
272843002457	catalytic residues [active]
272843002458	effector binding site; other site
272843002459	R2 peptide binding site; other site
272843002460	uncharacterized bacterial and archaeal solute carrier 6 subfamily; solute-binding domain; Region: SLC6sbd_u1; cd10334
272843002461	Na2 binding site [ion binding]; other site
272843002462	putative substrate binding site 1 [chemical binding]; other site
272843002463	Na binding site 1 [ion binding]; other site
272843002464	putative substrate binding site 2 [chemical binding]; other site
272843002465	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
272843002466	dimer interface [polypeptide binding]; other site
272843002467	putative radical transfer pathway; other site
272843002468	diiron center [ion binding]; other site
272843002469	tyrosyl radical; other site
272843002470	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
272843002471	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
272843002472	catalytic loop [active]
272843002473	iron binding site [ion binding]; other site
272843002474	tetrathionate reductase subunit A; Provisional; Region: PRK14991
272843002475	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
272843002476	molybdopterin cofactor binding site; other site
272843002477	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
272843002478	putative molybdopterin cofactor binding site [chemical binding]; other site
272843002479	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
272843002480	putative molybdopterin cofactor binding site; other site
272843002481	tetrathionate reductase subunit C; Provisional; Region: PRK14992
272843002482	tetrathionate reductase subunit B; Provisional; Region: PRK14993
272843002483	4Fe-4S binding domain; Region: Fer4; pfam00037
272843002484	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
272843002485	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
272843002486	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
272843002487	dimer interface [polypeptide binding]; other site
272843002488	phosphorylation site [posttranslational modification]
272843002489	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843002490	ATP binding site [chemical binding]; other site
272843002491	Mg2+ binding site [ion binding]; other site
272843002492	G-X-G motif; other site
272843002493	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
272843002494	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843002495	active site
272843002496	phosphorylation site [posttranslational modification]
272843002497	intermolecular recognition site; other site
272843002498	dimerization interface [polypeptide binding]; other site
272843002499	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
272843002500	DNA binding residues [nucleotide binding]
272843002501	dimerization interface [polypeptide binding]; other site
272843002502	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
272843002503	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
272843002504	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
272843002505	LysE type translocator; Region: LysE; cl00565
272843002506	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
272843002507	tetramer interfaces [polypeptide binding]; other site
272843002508	binuclear metal-binding site [ion binding]; other site
272843002509	Thiamine monophosphate kinase [Coenzyme metabolism]; Region: ThiL; COG0611
272843002510	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
272843002511	ATP binding site [chemical binding]; other site
272843002512	dimerization interface [polypeptide binding]; other site
272843002513	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
272843002514	putative RNA binding site [nucleotide binding]; other site
272843002515	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
272843002516	homopentamer interface [polypeptide binding]; other site
272843002517	active site
272843002518	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
272843002519	aromatic amino acid transport protein; Region: araaP; TIGR00837
272843002520	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
272843002521	dimer interface [polypeptide binding]; other site
272843002522	FMN binding site [chemical binding]; other site
272843002523	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
272843002524	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
272843002525	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
272843002526	protein binding site [polypeptide binding]; other site
272843002527	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
272843002528	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
272843002529	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
272843002530	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
272843002531	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
272843002532	nucleotide binding site [chemical binding]; other site
272843002533	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
272843002534	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
272843002535	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
272843002536	homodimer interface [polypeptide binding]; other site
272843002537	substrate-cofactor binding pocket; other site
272843002538	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843002539	catalytic residue [active]
272843002540	chaperone protein DnaJ; Provisional; Region: PRK10767
272843002541	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
272843002542	HSP70 interaction site [polypeptide binding]; other site
272843002543	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
272843002544	substrate binding site [polypeptide binding]; other site
272843002545	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
272843002546	Zn binding sites [ion binding]; other site
272843002547	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
272843002548	dimer interface [polypeptide binding]; other site
272843002549	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
272843002550	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
272843002551	N-terminal plug; other site
272843002552	ligand-binding site [chemical binding]; other site
272843002553	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
272843002554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843002555	Walker A/P-loop; other site
272843002556	ATP binding site [chemical binding]; other site
272843002557	Q-loop/lid; other site
272843002558	ABC transporter signature motif; other site
272843002559	Walker B; other site
272843002560	D-loop; other site
272843002561	H-loop/switch region; other site
272843002562	TOBE domain; Region: TOBE; pfam03459
272843002563	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
272843002564	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843002565	dimer interface [polypeptide binding]; other site
272843002566	conserved gate region; other site
272843002567	putative PBP binding loops; other site
272843002568	ABC-ATPase subunit interface; other site
272843002569	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
272843002570	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
272843002571	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
272843002572	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
272843002573	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843002574	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843002575	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
272843002576	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
272843002577	molybdenum-pterin binding domain; Region: Mop; TIGR00638
272843002578	TOBE domain; Region: TOBE; pfam03459
272843002579	5'-nucleotidase; Provisional; Region: PRK03826
272843002580	periplasmic serine pepetdase DegS; Region: protease_degS; TIGR02038
272843002581	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
272843002582	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
272843002583	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
272843002584	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
272843002585	catalytic motif [active]
272843002586	Zn binding site [ion binding]; other site
272843002587	RibD C-terminal domain; Region: RibD_C; cl17279
272843002588	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
272843002589	ATP cone domain; Region: ATP-cone; pfam03477
272843002590	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
272843002591	putative active site [active]
272843002592	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
272843002593	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
272843002594	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
272843002595	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
272843002596	ligand binding site [chemical binding]; other site
272843002597	homodimer interface [polypeptide binding]; other site
272843002598	NAD(P) binding site [chemical binding]; other site
272843002599	trimer interface B [polypeptide binding]; other site
272843002600	trimer interface A [polypeptide binding]; other site
272843002601	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
272843002602	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
272843002603	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
272843002604	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
272843002605	active site
272843002606	HIGH motif; other site
272843002607	dimer interface [polypeptide binding]; other site
272843002608	KMSKS motif; other site
272843002609	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
272843002610	RNA binding surface [nucleotide binding]; other site
272843002611	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
272843002612	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
272843002613	RNA binding site [nucleotide binding]; other site
272843002614	active site
272843002615	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
272843002616	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
272843002617	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
272843002618	translation initiation factor IF-2; Region: IF-2; TIGR00487
272843002619	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
272843002620	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
272843002621	G1 box; other site
272843002622	putative GEF interaction site [polypeptide binding]; other site
272843002623	GTP/Mg2+ binding site [chemical binding]; other site
272843002624	Switch I region; other site
272843002625	G2 box; other site
272843002626	G3 box; other site
272843002627	Switch II region; other site
272843002628	G4 box; other site
272843002629	G5 box; other site
272843002630	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
272843002631	Translation-initiation factor 2; Region: IF-2; pfam11987
272843002632	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
272843002633	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
272843002634	NusA N-terminal domain; Region: NusA_N; pfam08529
272843002635	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
272843002636	RNA binding site [nucleotide binding]; other site
272843002637	homodimer interface [polypeptide binding]; other site
272843002638	NusA-like KH domain; Region: KH_5; pfam13184
272843002639	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
272843002640	G-X-X-G motif; other site
272843002641	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
272843002642	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
272843002643	Sm and related proteins; Region: Sm_like; cl00259
272843002644	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
272843002645	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
272843002646	putative oligomer interface [polypeptide binding]; other site
272843002647	putative RNA binding site [nucleotide binding]; other site
272843002648	transcriptional repressor UlaR; Provisional; Region: PRK13509
272843002649	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
272843002650	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
272843002651	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
272843002652	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
272843002653	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
272843002654	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
272843002655	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
272843002656	active site
272843002657	P-loop; other site
272843002658	phosphorylation site [posttranslational modification]
272843002659	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
272843002660	active site
272843002661	phosphorylation site [posttranslational modification]
272843002662	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
272843002663	active site
272843002664	dimer interface [polypeptide binding]; other site
272843002665	magnesium binding site [ion binding]; other site
272843002666	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
272843002667	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843002668	ATP binding site [chemical binding]; other site
272843002669	putative Mg++ binding site [ion binding]; other site
272843002670	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843002671	nucleotide binding region [chemical binding]; other site
272843002672	ATP-binding site [chemical binding]; other site
272843002673	Helicase associated domain (HA2); Region: HA2; pfam04408
272843002674	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
272843002675	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
272843002676	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
272843002677	Predicted membrane protein [Function unknown]; Region: COG2707
272843002678	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
272843002679	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
272843002680	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsC; COG3563
272843002681	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
272843002682	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
272843002683	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
272843002684	active site
272843002685	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
272843002686	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
272843002687	active site
272843002688	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
272843002689	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
272843002690	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
272843002691	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
272843002692	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
272843002693	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
272843002694	active site
272843002695	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
272843002696	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
272843002697	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsE; COG3524
272843002698	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
272843002699	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
272843002700	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
272843002701	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
272843002702	Walker A/P-loop; other site
272843002703	ATP binding site [chemical binding]; other site
272843002704	Q-loop/lid; other site
272843002705	ABC transporter signature motif; other site
272843002706	Walker B; other site
272843002707	D-loop; other site
272843002708	H-loop/switch region; other site
272843002709	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
272843002710	putative GSH binding site [chemical binding]; other site
272843002711	catalytic residues [active]
272843002712	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
272843002713	Repair protein; Region: Repair_PSII; pfam04536
272843002714	Predicted membrane protein [Function unknown]; Region: COG3762
272843002715	LemA family; Region: LemA; pfam04011
272843002716	outer membrane protein A; Reviewed; Region: PRK10808
272843002717	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
272843002718	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
272843002719	ligand binding site [chemical binding]; other site
272843002720	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
272843002721	FAD binding domain; Region: FAD_binding_4; pfam01565
272843002722	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
272843002723	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
272843002724	CoenzymeA binding site [chemical binding]; other site
272843002725	subunit interaction site [polypeptide binding]; other site
272843002726	PHB binding site; other site
272843002727	ferrochelatase; Reviewed; Region: hemH; PRK00035
272843002728	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
272843002729	C-terminal domain interface [polypeptide binding]; other site
272843002730	active site
272843002731	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
272843002732	active site
272843002733	N-terminal domain interface [polypeptide binding]; other site
272843002734	selenophosphate synthetase; Provisional; Region: PRK00943
272843002735	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
272843002736	dimerization interface [polypeptide binding]; other site
272843002737	putative ATP binding site [chemical binding]; other site
272843002738	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
272843002739	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
272843002740	DNA binding site [nucleotide binding]
272843002741	domain linker motif; other site
272843002742	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
272843002743	putative ligand binding site [chemical binding]; other site
272843002744	putative dimerization interface [polypeptide binding]; other site
272843002745	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
272843002746	Shikimate kinase; Region: SKI; pfam01202
272843002747	ATP-binding site [chemical binding]; other site
272843002748	Gluconate-6-phosphate binding site [chemical binding]; other site
272843002749	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
272843002750	fructuronate transporter; Provisional; Region: PRK10034; cl15264
272843002751	cystathionine beta-lyase; Provisional; Region: PRK08114
272843002752	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
272843002753	homodimer interface [polypeptide binding]; other site
272843002754	substrate-cofactor binding pocket; other site
272843002755	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843002756	catalytic residue [active]
272843002757	peroxidase; Provisional; Region: PRK15000
272843002758	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
272843002759	dimer interface [polypeptide binding]; other site
272843002760	decamer (pentamer of dimers) interface [polypeptide binding]; other site
272843002761	catalytic triad [active]
272843002762	peroxidatic and resolving cysteines [active]
272843002763	translation initiation factor Sui1; Validated; Region: PRK06824
272843002764	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
272843002765	putative rRNA binding site [nucleotide binding]; other site
272843002766	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
272843002767	active site
272843002768	dimer interface [polypeptide binding]; other site
272843002769	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
272843002770	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cl00202
272843002771	iron binding site [ion binding]; other site
272843002772	Predicted membrane protein [Function unknown]; Region: COG3771
272843002773	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
272843002774	IHF dimer interface [polypeptide binding]; other site
272843002775	IHF - DNA interface [nucleotide binding]; other site
272843002776	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
272843002777	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
272843002778	RNA binding site [nucleotide binding]; other site
272843002779	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
272843002780	RNA binding site [nucleotide binding]; other site
272843002781	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
272843002782	RNA binding site [nucleotide binding]; other site
272843002783	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
272843002784	RNA binding site [nucleotide binding]; other site
272843002785	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
272843002786	RNA binding site [nucleotide binding]; other site
272843002787	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
272843002788	RNA binding site [nucleotide binding]; other site
272843002789	cytidylate kinase; Provisional; Region: cmk; PRK00023
272843002790	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
272843002791	CMP-binding site; other site
272843002792	The sites determining sugar specificity; other site
272843002793	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
272843002794	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
272843002795	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
272843002796	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
272843002797	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
272843002798	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
272843002799	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
272843002800	Protein of unknown function (DUF2618); Region: DUF2618; pfam10940
272843002801	ornithine decarboxylase; Provisional; Region: PRK13578
272843002802	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
272843002803	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
272843002804	homodimer interface [polypeptide binding]; other site
272843002805	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843002806	catalytic residue [active]
272843002807	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
272843002808	putrescine transporter; Provisional; Region: potE; PRK10655
272843002809	ornithine carbamoyltransferase; Validated; Region: PRK02102
272843002810	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
272843002811	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
272843002812	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
272843002813	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
272843002814	aromatic amino acid transport protein; Region: araaP; TIGR00837
272843002815	tyrosine phenol-lyase; Provisional; Region: PRK13237
272843002816	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
272843002817	substrate binding site [chemical binding]; other site
272843002818	tetramer interface [polypeptide binding]; other site
272843002819	catalytic residue [active]
272843002820	argininosuccinate synthase; Validated; Region: PRK05370
272843002821	argininosuccinate synthase; Provisional; Region: PRK13820
272843002822	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
272843002823	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
272843002824	putative NAD(P) binding site [chemical binding]; other site
272843002825	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
272843002826	ATP binding site [chemical binding]; other site
272843002827	active site
272843002828	substrate binding site [chemical binding]; other site
272843002829	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
272843002830	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
272843002831	G1 box; other site
272843002832	putative GEF interaction site [polypeptide binding]; other site
272843002833	GTP/Mg2+ binding site [chemical binding]; other site
272843002834	Switch I region; other site
272843002835	G2 box; other site
272843002836	G3 box; other site
272843002837	Switch II region; other site
272843002838	G4 box; other site
272843002839	G5 box; other site
272843002840	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
272843002841	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
272843002842	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
272843002843	dimerization interface [polypeptide binding]; other site
272843002844	DPS ferroxidase diiron center [ion binding]; other site
272843002845	ion pore; other site
272843002846	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
272843002847	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
272843002848	HIGH motif; other site
272843002849	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
272843002850	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
272843002851	active site
272843002852	KMSKS motif; other site
272843002853	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
272843002854	tRNA binding surface [nucleotide binding]; other site
272843002855	anticodon binding site; other site
272843002856	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
272843002857	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
272843002858	dimer interface [polypeptide binding]; other site
272843002859	catalytic triad [active]
272843002860	peroxidatic and resolving cysteines [active]
272843002861	putative septicolysin, cholesterol-dependent cytolysin family and related proteins; Region: septicolysin_like; cd12208
272843002862	oligomer interface [polypeptide binding]; other site
272843002863	DNA polymerase III subunit chi; Validated; Region: PRK05728
272843002864	fumarate hydratase; Reviewed; Region: fumC; PRK00485
272843002865	Class II fumarases; Region: Fumarase_classII; cd01362
272843002866	active site
272843002867	tetramer interface [polypeptide binding]; other site
272843002868	hypothetical protein; Provisional; Region: PRK04940
272843002869	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
272843002870	ATP-grasp domain; Region: ATP-grasp_4; cl17255
272843002871	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
272843002872	GSH binding site [chemical binding]; other site
272843002873	catalytic residues [active]
272843002874	N-acetylglutamate synthase; Validated; Region: PRK05279
272843002875	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
272843002876	putative feedback inhibition sensing region; other site
272843002877	putative nucleotide binding site [chemical binding]; other site
272843002878	putative substrate binding site [chemical binding]; other site
272843002879	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
272843002880	Coenzyme A binding pocket [chemical binding]; other site
272843002881	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
272843002882	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
272843002883	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
272843002884	Predicted membrane protein [Function unknown]; Region: COG4811
272843002885	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
272843002886	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
272843002887	trimer interface [polypeptide binding]; other site
272843002888	eyelet of channel; other site
272843002889	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
272843002890	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
272843002891	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
272843002892	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
272843002893	active pocket/dimerization site; other site
272843002894	active site
272843002895	phosphorylation site [posttranslational modification]
272843002896	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
272843002897	active site
272843002898	phosphorylation site [posttranslational modification]
272843002899	benzoate transport; Region: 2A0115; TIGR00895
272843002900	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843002901	putative substrate translocation pore; other site
272843002902	hypothetical protein; Provisional; Region: PRK05423
272843002903	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
272843002904	homodimer interface [polypeptide binding]; other site
272843002905	substrate-cofactor binding pocket; other site
272843002906	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843002907	catalytic residue [active]
272843002908	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
272843002909	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
272843002910	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843002911	homodimer interface [polypeptide binding]; other site
272843002912	catalytic residue [active]
272843002913	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
272843002914	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
272843002915	hinge; other site
272843002916	active site
272843002917	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
272843002918	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843002919	S-adenosylmethionine binding site [chemical binding]; other site
272843002920	DNA gyrase subunit A; Validated; Region: PRK05560
272843002921	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
272843002922	CAP-like domain; other site
272843002923	active site
272843002924	primary dimer interface [polypeptide binding]; other site
272843002925	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
272843002926	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
272843002927	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
272843002928	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
272843002929	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
272843002930	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
272843002931	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3094
272843002932	Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961
272843002933	Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400
272843002934	TadE-like protein; Region: TadE; pfam07811
272843002935	TadE-like protein; Region: TadE; pfam07811
272843002936	Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking and secretion]; Region: TadD; COG5010
272843002937	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
272843002938	binding surface
272843002939	TPR motif; other site
272843002940	Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064
272843002941	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
272843002942	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
272843002943	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
272843002944	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
272843002945	ATP binding site [chemical binding]; other site
272843002946	Walker A motif; other site
272843002947	hexamer interface [polypeptide binding]; other site
272843002948	Walker B motif; other site
272843002949	Flp pilus assembly protein, ATPase CpaE [Intracellular trafficking and secretion]; Region: CpaE; COG4963
272843002950	This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111
272843002951	Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964
272843002952	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
272843002953	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
272843002954	Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960
272843002955	Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847
272843002956	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
272843002957	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
272843002958	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
272843002959	GIY-YIG motif/motif A; other site
272843002960	active site
272843002961	catalytic site [active]
272843002962	putative DNA binding site [nucleotide binding]; other site
272843002963	metal binding site [ion binding]; metal-binding site
272843002964	UvrB/uvrC motif; Region: UVR; pfam02151
272843002965	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
272843002966	Helix-hairpin-helix motif; Region: HHH; pfam00633
272843002967	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
272843002968	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
272843002969	Ligand binding site; other site
272843002970	oligomer interface; other site
272843002971	Uncharacterized conserved protein [Function unknown]; Region: COG2835
272843002972	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
272843002973	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
272843002974	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
272843002975	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
272843002976	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
272843002977	Walker A/P-loop; other site
272843002978	ATP binding site [chemical binding]; other site
272843002979	Q-loop/lid; other site
272843002980	ABC transporter signature motif; other site
272843002981	Walker B; other site
272843002982	D-loop; other site
272843002983	H-loop/switch region; other site
272843002984	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
272843002985	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
272843002986	Competence protein; Region: Competence; pfam03772
272843002987	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
272843002988	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
272843002989	poly(A) polymerase; Region: pcnB; TIGR01942
272843002990	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
272843002991	active site
272843002992	NTP binding site [chemical binding]; other site
272843002993	metal binding triad [ion binding]; metal-binding site
272843002994	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
272843002995	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
272843002996	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
272843002997	catalytic center binding site [active]
272843002998	ATP binding site [chemical binding]; other site
272843002999	Homoserine acetyltransferase [Amino acid transport and metabolism]; Region: MET2; COG2021
272843003000	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
272843003001	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
272843003002	putative active site [active]
272843003003	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
272843003004	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
272843003005	DNA binding site [nucleotide binding]
272843003006	domain linker motif; other site
272843003007	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
272843003008	dimerization interface [polypeptide binding]; other site
272843003009	ligand binding site [chemical binding]; other site
272843003010	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
272843003011	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
272843003012	putative valine binding site [chemical binding]; other site
272843003013	dimer interface [polypeptide binding]; other site
272843003014	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
272843003015	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK06882
272843003016	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
272843003017	PYR/PP interface [polypeptide binding]; other site
272843003018	dimer interface [polypeptide binding]; other site
272843003019	TPP binding site [chemical binding]; other site
272843003020	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
272843003021	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
272843003022	TPP-binding site [chemical binding]; other site
272843003023	dimer interface [polypeptide binding]; other site
272843003024	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
272843003025	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
272843003026	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
272843003027	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
272843003028	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
272843003029	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
272843003030	putative active site [active]
272843003031	putative substrate binding site [chemical binding]; other site
272843003032	putative cosubstrate binding site; other site
272843003033	catalytic site [active]
272843003034	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
272843003035	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
272843003036	active site
272843003037	dimer interface [polypeptide binding]; other site
272843003038	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
272843003039	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
272843003040	active site
272843003041	trimer interface [polypeptide binding]; other site
272843003042	allosteric site; other site
272843003043	active site lid [active]
272843003044	hexamer (dimer of trimers) interface [polypeptide binding]; other site
272843003045	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
272843003046	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
272843003047	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
272843003048	active site turn [active]
272843003049	phosphorylation site [posttranslational modification]
272843003050	ABC transporter ATPase component; Reviewed; Region: PRK11147
272843003051	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
272843003052	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
272843003053	ABC transporter; Region: ABC_tran_2; pfam12848
272843003054	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
272843003055	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK05318
272843003056	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
272843003057	Zn2+ binding site [ion binding]; other site
272843003058	Mg2+ binding site [ion binding]; other site
272843003059	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
272843003060	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
272843003061	hypothetical protein; Provisional; Region: PRK01821
272843003062	Staphylococcal nuclease homologues; Region: SNc; smart00318
272843003063	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
272843003064	Catalytic site; other site
272843003065	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
272843003066	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
272843003067	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
272843003068	catalytic residue [active]
272843003069	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
272843003070	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
272843003071	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
272843003072	putative ribose interaction site [chemical binding]; other site
272843003073	putative ADP binding site [chemical binding]; other site
272843003074	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
272843003075	active site
272843003076	nucleotide binding site [chemical binding]; other site
272843003077	HIGH motif; other site
272843003078	KMSKS motif; other site
272843003079	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
272843003080	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
272843003081	putative acyl-acceptor binding pocket; other site
272843003082	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
272843003083	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
272843003084	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
272843003085	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
272843003086	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
272843003087	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
272843003088	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843003089	Walker A/P-loop; other site
272843003090	ATP binding site [chemical binding]; other site
272843003091	Q-loop/lid; other site
272843003092	ABC transporter signature motif; other site
272843003093	Walker B; other site
272843003094	D-loop; other site
272843003095	H-loop/switch region; other site
272843003096	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843003097	Walker A/P-loop; other site
272843003098	ATP binding site [chemical binding]; other site
272843003099	Q-loop/lid; other site
272843003100	ABC transporter signature motif; other site
272843003101	Walker B; other site
272843003102	D-loop; other site
272843003103	H-loop/switch region; other site
272843003104	serine/threonine transporter SstT; Provisional; Region: PRK13628
272843003105	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
272843003106	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
272843003107	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
272843003108	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
272843003109	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
272843003110	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
272843003111	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
272843003112	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
272843003113	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
272843003114	E3 interaction surface; other site
272843003115	lipoyl attachment site [posttranslational modification]; other site
272843003116	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
272843003117	E3 interaction surface; other site
272843003118	lipoyl attachment site [posttranslational modification]; other site
272843003119	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
272843003120	E3 interaction surface; other site
272843003121	lipoyl attachment site [posttranslational modification]; other site
272843003122	e3 binding domain; Region: E3_binding; pfam02817
272843003123	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
272843003124	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
272843003125	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
272843003126	dimer interface [polypeptide binding]; other site
272843003127	TPP-binding site [chemical binding]; other site
272843003128	Transketolase, pyrimidine binding domain; Region: Transket_pyr; smart00861
272843003129	PTS system glucose-specific transporter subunit; Provisional; Region: PRK09439
272843003130	HPr interaction site; other site
272843003131	glycerol kinase (GK) interaction site [polypeptide binding]; other site
272843003132	active site
272843003133	phosphorylation site [posttranslational modification]
272843003134	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
272843003135	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
272843003136	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
272843003137	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
272843003138	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
272843003139	dimerization domain swap beta strand [polypeptide binding]; other site
272843003140	regulatory protein interface [polypeptide binding]; other site
272843003141	active site
272843003142	regulatory phosphorylation site [posttranslational modification]; other site
272843003143	GTPase RsgA; Reviewed; Region: PRK12288
272843003144	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
272843003145	RNA binding site [nucleotide binding]; other site
272843003146	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
272843003147	GTPase/Zn-binding domain interface [polypeptide binding]; other site
272843003148	GTP/Mg2+ binding site [chemical binding]; other site
272843003149	G4 box; other site
272843003150	G5 box; other site
272843003151	G1 box; other site
272843003152	Switch I region; other site
272843003153	G2 box; other site
272843003154	G3 box; other site
272843003155	Switch II region; other site
272843003156	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
272843003157	catalytic site [active]
272843003158	putative active site [active]
272843003159	putative substrate binding site [chemical binding]; other site
272843003160	dimer interface [polypeptide binding]; other site
272843003161	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
272843003162	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
272843003163	active site
272843003164	metal binding site [ion binding]; metal-binding site
272843003165	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
272843003166	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
272843003167	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
272843003168	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
272843003169	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843003170	ATP binding site [chemical binding]; other site
272843003171	Mg2+ binding site [ion binding]; other site
272843003172	G-X-G motif; other site
272843003173	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
272843003174	ATP binding site [chemical binding]; other site
272843003175	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
272843003176	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
272843003177	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
272843003178	bacterial Hfq-like; Region: Hfq; cd01716
272843003179	hexamer interface [polypeptide binding]; other site
272843003180	Sm1 motif; other site
272843003181	RNA binding site [nucleotide binding]; other site
272843003182	Sm2 motif; other site
272843003183	GTPase HflX; Provisional; Region: PRK11058
272843003184	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
272843003185	HflX GTPase family; Region: HflX; cd01878
272843003186	G1 box; other site
272843003187	GTP/Mg2+ binding site [chemical binding]; other site
272843003188	Switch I region; other site
272843003189	G2 box; other site
272843003190	G3 box; other site
272843003191	Switch II region; other site
272843003192	G4 box; other site
272843003193	G5 box; other site
272843003194	Transcriptional regulator of aromatic amino acids metabolism [Transcription / Amino acid transport and metabolism]; Region: TyrR; COG3283
272843003195	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843003196	Walker A motif; other site
272843003197	ATP binding site [chemical binding]; other site
272843003198	Walker B motif; other site
272843003199	arginine finger; other site
272843003200	Predicted membrane protein [Function unknown]; Region: COG3768
272843003201	Domain of unknown function (DUF697); Region: DUF697; cl12064
272843003202	Predicted ATPase [General function prediction only]; Region: COG3106
272843003203	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
272843003204	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
272843003205	peptide binding site [polypeptide binding]; other site
272843003206	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SapB; COG4168
272843003207	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843003208	dimer interface [polypeptide binding]; other site
272843003209	conserved gate region; other site
272843003210	putative PBP binding loops; other site
272843003211	ABC-ATPase subunit interface; other site
272843003212	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SapC; COG4171
272843003213	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
272843003214	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843003215	dimer interface [polypeptide binding]; other site
272843003216	conserved gate region; other site
272843003217	putative PBP binding loops; other site
272843003218	ABC-ATPase subunit interface; other site
272843003219	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SapD; COG4170
272843003220	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
272843003221	Walker A/P-loop; other site
272843003222	ATP binding site [chemical binding]; other site
272843003223	Q-loop/lid; other site
272843003224	ABC transporter signature motif; other site
272843003225	Walker B; other site
272843003226	D-loop; other site
272843003227	H-loop/switch region; other site
272843003228	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
272843003229	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SapF; COG4167
272843003230	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
272843003231	Walker A/P-loop; other site
272843003232	ATP binding site [chemical binding]; other site
272843003233	Q-loop/lid; other site
272843003234	ABC transporter signature motif; other site
272843003235	Walker B; other site
272843003236	D-loop; other site
272843003237	H-loop/switch region; other site
272843003238	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
272843003239	classical (c) SDRs; Region: SDR_c; cd05233
272843003240	NAD(P) binding site [chemical binding]; other site
272843003241	active site
272843003242	glutamate racemase; Provisional; Region: PRK00865
272843003243	Chorismate lyase; Region: Chor_lyase; pfam04345
272843003244	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
272843003245	Pathogenicity locus; Region: Cdd1; pfam11731
272843003246	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
272843003247	generic binding surface II; other site
272843003248	ssDNA binding site; other site
272843003249	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843003250	ATP binding site [chemical binding]; other site
272843003251	putative Mg++ binding site [ion binding]; other site
272843003252	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843003253	nucleotide binding region [chemical binding]; other site
272843003254	ATP-binding site [chemical binding]; other site
272843003255	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
272843003256	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
272843003257	Zn2+ binding site [ion binding]; other site
272843003258	Mg2+ binding site [ion binding]; other site
272843003259	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
272843003260	synthetase active site [active]
272843003261	NTP binding site [chemical binding]; other site
272843003262	metal binding site [ion binding]; metal-binding site
272843003263	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
272843003264	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
272843003265	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
272843003266	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
272843003267	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
272843003268	catalytic site [active]
272843003269	G-X2-G-X-G-K; other site
272843003270	methionine sulfoxide reductase B; Provisional; Region: PRK00222
272843003271	SelR domain; Region: SelR; pfam01641
272843003272	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
272843003273	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
272843003274	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
272843003275	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
272843003276	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
272843003277	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
272843003278	acyl-activating enzyme (AAE) consensus motif; other site
272843003279	putative AMP binding site [chemical binding]; other site
272843003280	putative active site [active]
272843003281	putative CoA binding site [chemical binding]; other site
272843003282	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
272843003283	intersubunit interface [polypeptide binding]; other site
272843003284	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
272843003285	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
272843003286	metal binding site [ion binding]; metal-binding site
272843003287	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
272843003288	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
272843003289	putative ATP binding site [chemical binding]; other site
272843003290	putative substrate interface [chemical binding]; other site
272843003291	murein transglycosylase A; Provisional; Region: mltA; PRK11162
272843003292	MltA specific insert domain; Region: MltA; smart00925
272843003293	3D domain; Region: 3D; pfam06725
272843003294	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
272843003295	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
272843003296	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
272843003297	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
272843003298	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
272843003299	AMP binding site [chemical binding]; other site
272843003300	metal binding site [ion binding]; metal-binding site
272843003301	active site
272843003302	hypothetical protein; Provisional; Region: PRK07338
272843003303	M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme; Region: M20_CPDG2; cd03885
272843003304	metal binding site [ion binding]; metal-binding site
272843003305	dimer interface [polypeptide binding]; other site
272843003306	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
272843003307	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
272843003308	Predicted membrane protein [Function unknown]; Region: COG2860
272843003309	UPF0126 domain; Region: UPF0126; pfam03458
272843003310	UPF0126 domain; Region: UPF0126; pfam03458
272843003311	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
272843003312	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
272843003313	putative catalytic cysteine [active]
272843003314	aspartate kinase III; Validated; Region: PRK09084
272843003315	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
272843003316	nucleotide binding site [chemical binding]; other site
272843003317	substrate binding site [chemical binding]; other site
272843003318	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
272843003319	lysine allosteric regulatory site; other site
272843003320	dimer interface [polypeptide binding]; other site
272843003321	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
272843003322	dimer interface [polypeptide binding]; other site
272843003323	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
272843003324	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
272843003325	GDP-binding site [chemical binding]; other site
272843003326	ACT binding site; other site
272843003327	IMP binding site; other site
272843003328	Haem-binding domain; Region: Haem_bd; pfam14376
272843003329	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
272843003330	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
272843003331	ATP cone domain; Region: ATP-cone; pfam03477
272843003332	Class III ribonucleotide reductase; Region: RNR_III; cd01675
272843003333	effector binding site; other site
272843003334	active site
272843003335	Zn binding site [ion binding]; other site
272843003336	glycine loop; other site
272843003337	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
272843003338	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843003339	FeS/SAM binding site; other site
272843003340	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
272843003341	active site
272843003342	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
272843003343	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
272843003344	substrate binding site [chemical binding]; other site
272843003345	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
272843003346	substrate binding site [chemical binding]; other site
272843003347	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
272843003348	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
272843003349	active site
272843003350	HIGH motif; other site
272843003351	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
272843003352	KMSKS motif; other site
272843003353	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
272843003354	tRNA binding surface [nucleotide binding]; other site
272843003355	anticodon binding site; other site
272843003356	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
272843003357	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
272843003358	putative metal binding site [ion binding]; other site
272843003359	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
272843003360	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
272843003361	active site
272843003362	intersubunit interface [polypeptide binding]; other site
272843003363	catalytic residue [active]
272843003364	putative transporter; Provisional; Region: PRK11660
272843003365	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
272843003366	Sulfate transporter family; Region: Sulfate_transp; pfam00916
272843003367	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
272843003368	putative arabinose transporter; Provisional; Region: PRK03545
272843003369	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843003370	putative substrate translocation pore; other site
272843003371	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
272843003372	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
272843003373	trimer interface [polypeptide binding]; other site
272843003374	active site
272843003375	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
272843003376	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
272843003377	Sugar specificity; other site
272843003378	Pyrimidine base specificity; other site
272843003379	ATP-binding site [chemical binding]; other site
272843003380	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
272843003381	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
272843003382	2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate binding protein; Region: PhnS; TIGR03227
272843003383	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
272843003384	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
272843003385	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
272843003386	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
272843003387	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843003388	dimer interface [polypeptide binding]; other site
272843003389	conserved gate region; other site
272843003390	putative PBP binding loops; other site
272843003391	ABC-ATPase subunit interface; other site
272843003392	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843003393	dimer interface [polypeptide binding]; other site
272843003394	conserved gate region; other site
272843003395	putative PBP binding loops; other site
272843003396	ABC-ATPase subunit interface; other site
272843003397	ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432
272843003398	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
272843003399	Walker A/P-loop; other site
272843003400	ATP binding site [chemical binding]; other site
272843003401	Q-loop/lid; other site
272843003402	ABC transporter signature motif; other site
272843003403	Walker B; other site
272843003404	D-loop; other site
272843003405	H-loop/switch region; other site
272843003406	TOBE domain; Region: TOBE_2; pfam08402
272843003407	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
272843003408	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
272843003409	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843003410	S-adenosylmethionine binding site [chemical binding]; other site
272843003411	DNA polymerase III, psi subunit [DNA replication, recombination, and repair]; Region: HolD; COG3050
272843003412	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
272843003413	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
272843003414	Coenzyme A binding pocket [chemical binding]; other site
272843003415	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
272843003416	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
272843003417	Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011
272843003418	Protein of unknown function (DUF2572); Region: DUF2572; pfam10833
272843003419	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
272843003420	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
272843003421	ligand binding site [chemical binding]; other site
272843003422	translocation protein TolB; Provisional; Region: tolB; PRK01742
272843003423	TolB amino-terminal domain; Region: TolB_N; pfam04052
272843003424	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
272843003425	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
272843003426	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
272843003427	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
272843003428	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
272843003429	TolA C-terminal; Region: TolA; pfam06519
272843003430	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
272843003431	colicin uptake protein TolR; Provisional; Region: PRK11024
272843003432	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
272843003433	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
272843003434	active site
272843003435	Predicted membrane protein [Function unknown]; Region: COG3790
272843003436	cytochrome d oxidase, subunit II (cydB); Region: cydB; TIGR00203
272843003437	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
272843003438	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
272843003439	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
272843003440	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
272843003441	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843003442	Walker A motif; other site
272843003443	ATP binding site [chemical binding]; other site
272843003444	Walker B motif; other site
272843003445	arginine finger; other site
272843003446	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
272843003447	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
272843003448	RuvA N terminal domain; Region: RuvA_N; pfam01330
272843003449	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
272843003450	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
272843003451	active site
272843003452	putative DNA-binding cleft [nucleotide binding]; other site
272843003453	dimer interface [polypeptide binding]; other site
272843003454	hypothetical protein; Validated; Region: PRK00110
272843003455	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
272843003456	nudix motif; other site
272843003457	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
272843003458	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
272843003459	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
272843003460	dimer interface [polypeptide binding]; other site
272843003461	anticodon binding site; other site
272843003462	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
272843003463	homodimer interface [polypeptide binding]; other site
272843003464	motif 1; other site
272843003465	active site
272843003466	motif 2; other site
272843003467	GAD domain; Region: GAD; pfam02938
272843003468	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
272843003469	active site
272843003470	motif 3; other site
272843003471	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1755
272843003472	Methyltransferase domain; Region: Methyltransf_31; pfam13847
272843003473	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843003474	S-adenosylmethionine binding site [chemical binding]; other site
272843003475	Predicted membrane protein [Function unknown]; Region: COG4984
272843003476	Predicted membrane protein (DUF2157); Region: DUF2157; pfam09925
272843003477	Uncharacterized membrane-anchored protein [Function unknown]; Region: COG4929
272843003478	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
272843003479	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
272843003480	dimer interface [polypeptide binding]; other site
272843003481	active site
272843003482	metal binding site [ion binding]; metal-binding site
272843003483	glutathione binding site [chemical binding]; other site
272843003484	ribonuclease T; Provisional; Region: PRK05168
272843003485	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
272843003486	active site
272843003487	catalytic site [active]
272843003488	substrate binding site [chemical binding]; other site
272843003489	Predicted permease [General function prediction only]; Region: COG2056
272843003490	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
272843003491	Primosomal replication protein N'' [DNA replication, recombination, and repair]; Region: PriC; COG3923
272843003492	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
272843003493	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
272843003494	homodimer interface [polypeptide binding]; other site
272843003495	oligonucleotide binding site [chemical binding]; other site
272843003496	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
272843003497	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
272843003498	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
272843003499	RNA binding surface [nucleotide binding]; other site
272843003500	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
272843003501	active site
272843003502	NAD-dependent deacetylase; Provisional; Region: PRK00481
272843003503	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
272843003504	NAD+ binding site [chemical binding]; other site
272843003505	substrate binding site [chemical binding]; other site
272843003506	Zn binding site [ion binding]; other site
272843003507	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
272843003508	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
272843003509	catalytic residues [active]
272843003510	cystathionine gamma-synthase; Reviewed; Region: PRK08247
272843003511	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
272843003512	homodimer interface [polypeptide binding]; other site
272843003513	substrate-cofactor binding pocket; other site
272843003514	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843003515	catalytic residue [active]
272843003516	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
272843003517	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
272843003518	Walker A/P-loop; other site
272843003519	ATP binding site [chemical binding]; other site
272843003520	Q-loop/lid; other site
272843003521	ABC transporter signature motif; other site
272843003522	Walker B; other site
272843003523	D-loop; other site
272843003524	H-loop/switch region; other site
272843003525	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
272843003526	FtsX-like permease family; Region: FtsX; pfam02687
272843003527	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
272843003528	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
272843003529	HlyD family secretion protein; Region: HlyD_3; pfam13437
272843003530	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
272843003531	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
272843003532	pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569
272843003533	active site
272843003534	Neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: NanH; COG4409
272843003535	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
272843003536	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
272843003537	Asp-box motif; other site
272843003538	catalytic site [active]
272843003539	Autotransporter beta-domain; Region: Autotransporter; smart00869
272843003540	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
272843003541	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
272843003542	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843003543	FeS/SAM binding site; other site
272843003544	TRAM domain; Region: TRAM; pfam01938
272843003545	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
272843003546	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
272843003547	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
272843003548	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
272843003549	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
272843003550	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
272843003551	Preprotein translocase subunit SecD [Intracellular trafficking and secretion]; Region: SecD; COG0342
272843003552	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
272843003553	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
272843003554	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
272843003555	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
272843003556	NAD(P) binding site [chemical binding]; other site
272843003557	homodimer interface [polypeptide binding]; other site
272843003558	substrate binding site [chemical binding]; other site
272843003559	active site
272843003560	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
272843003561	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
272843003562	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
272843003563	NAD(P) binding site [chemical binding]; other site
272843003564	active site
272843003565	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
272843003566	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
272843003567	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
272843003568	active site
272843003569	homodimer interface [polypeptide binding]; other site
272843003570	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
272843003571	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
272843003572	Bacterial sugar transferase; Region: Bac_transf; pfam02397
272843003573	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
272843003574	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
272843003575	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
272843003576	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
272843003577	inhibitor-cofactor binding pocket; inhibition site
272843003578	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843003579	catalytic residue [active]
272843003580	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
272843003581	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
272843003582	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
272843003583	NAD(P) binding site [chemical binding]; other site
272843003584	homodimer interface [polypeptide binding]; other site
272843003585	substrate binding site [chemical binding]; other site
272843003586	active site
272843003587	polysaccharide export protein Wza; Provisional; Region: PRK15078
272843003588	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
272843003589	SLBB domain; Region: SLBB; pfam10531
272843003590	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
272843003591	Low molecular weight phosphatase family; Region: LMWPc; cd00115
272843003592	active site
272843003593	tyrosine kinase; Provisional; Region: PRK11519
272843003594	Chain length determinant protein; Region: Wzz; pfam02706
272843003595	Chain length determinant protein; Region: Wzz; cl15801
272843003596	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
272843003597	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
272843003598	P loop; other site
272843003599	Nucleotide binding site [chemical binding]; other site
272843003600	DTAP/Switch II; other site
272843003601	Switch I; other site
272843003602	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
272843003603	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
272843003604	active site
272843003605	metal binding site [ion binding]; metal-binding site
272843003606	hexamer interface [polypeptide binding]; other site
272843003607	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
272843003608	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
272843003609	dimer interface [polypeptide binding]; other site
272843003610	ADP-ribose binding site [chemical binding]; other site
272843003611	active site
272843003612	nudix motif; other site
272843003613	metal binding site [ion binding]; metal-binding site
272843003614	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
272843003615	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
272843003616	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
272843003617	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
272843003618	metal binding site [ion binding]; metal-binding site
272843003619	dimer interface [polypeptide binding]; other site
272843003620	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
272843003621	ArsC family; Region: ArsC; pfam03960
272843003622	putative catalytic residues [active]
272843003623	heat shock protein 90; Provisional; Region: PRK05218
272843003624	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843003625	ATP binding site [chemical binding]; other site
272843003626	Mg2+ binding site [ion binding]; other site
272843003627	G-X-G motif; other site
272843003628	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
272843003629	hypothetical protein; Provisional; Region: PRK04860
272843003630	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
272843003631	S-adenosylmethionine synthetase; Validated; Region: PRK05250
272843003632	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
272843003633	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
272843003634	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
272843003635	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
272843003636	active site
272843003637	multimer interface [polypeptide binding]; other site
272843003638	aminopeptidase B; Provisional; Region: PRK05015
272843003639	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
272843003640	interface (dimer of trimers) [polypeptide binding]; other site
272843003641	Substrate-binding/catalytic site; other site
272843003642	Zn-binding sites [ion binding]; other site
272843003643	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
272843003644	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
272843003645	NAD binding site [chemical binding]; other site
272843003646	substrate binding site [chemical binding]; other site
272843003647	homodimer interface [polypeptide binding]; other site
272843003648	active site
272843003649	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
272843003650	rRNA binding site [nucleotide binding]; other site
272843003651	predicted 30S ribosome binding site; other site
272843003652	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
272843003653	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
272843003654	putative active site [active]
272843003655	catalytic triad [active]
272843003656	putative dimer interface [polypeptide binding]; other site
272843003657	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
272843003658	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
272843003659	Transporter associated domain; Region: CorC_HlyC; smart01091
272843003660	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
272843003661	active site
272843003662	catalytic residues [active]
272843003663	galactokinase; Provisional; Region: PRK05101
272843003664	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
272843003665	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
272843003666	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
272843003667	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
272843003668	dimer interface [polypeptide binding]; other site
272843003669	active site
272843003670	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
272843003671	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
272843003672	DNA binding site [nucleotide binding]
272843003673	domain linker motif; other site
272843003674	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
272843003675	ligand binding site [chemical binding]; other site
272843003676	dimerization interface (closed form) [polypeptide binding]; other site
272843003677	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
272843003678	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
272843003679	ligand binding site [chemical binding]; other site
272843003680	calcium binding site [ion binding]; other site
272843003681	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
272843003682	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
272843003683	Walker A/P-loop; other site
272843003684	ATP binding site [chemical binding]; other site
272843003685	Q-loop/lid; other site
272843003686	ABC transporter signature motif; other site
272843003687	Walker B; other site
272843003688	D-loop; other site
272843003689	H-loop/switch region; other site
272843003690	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
272843003691	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
272843003692	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
272843003693	TM-ABC transporter signature motif; other site
272843003694	transcription-repair coupling factor; Provisional; Region: PRK10689
272843003695	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
272843003696	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843003697	ATP binding site [chemical binding]; other site
272843003698	putative Mg++ binding site [ion binding]; other site
272843003699	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843003700	nucleotide binding region [chemical binding]; other site
272843003701	ATP-binding site [chemical binding]; other site
272843003702	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
272843003703	putative metal dependent hydrolase; Provisional; Region: PRK11598
272843003704	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
272843003705	Sulfatase; Region: Sulfatase; pfam00884
272843003706	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
272843003707	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
272843003708	Helicase; Region: Helicase_RecD; pfam05127
272843003709	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
272843003710	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
272843003711	phosphodiesterase; Provisional; Region: PRK12704
272843003712	metal-binding heat shock protein; Provisional; Region: PRK00016
272843003713	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
272843003714	PhoH-like protein; Region: PhoH; pfam02562
272843003715	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
272843003716	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843003717	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
272843003718	Gamma-glutamylcysteine synthetase [Coenzyme metabolism]; Region: GshA; COG2918
272843003719	ATP-grasp domain; Region: ATP-grasp_4; cl17255
272843003720	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
272843003721	EamA-like transporter family; Region: EamA; cl17759
272843003722	Uncharacterized lipoprotein [Cell envelope biogenesis, outer membrane]; Region: NlpB; COG3317
272843003723	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
272843003724	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
272843003725	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
272843003726	dihydrodipicolinate synthase; Region: dapA; TIGR00674
272843003727	dimer interface [polypeptide binding]; other site
272843003728	active site
272843003729	catalytic residue [active]
272843003730	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
272843003731	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
272843003732	catalytic triad [active]
272843003733	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
272843003734	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
272843003735	ATP-grasp domain; Region: ATP-grasp; pfam02222
272843003736	S-ribosylhomocysteinase; Provisional; Region: PRK02260
272843003737	Predicted membrane protein [Function unknown]; Region: COG1238
272843003738	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
272843003739	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
272843003740	active site
272843003741	substrate binding site [chemical binding]; other site
272843003742	trimer interface [polypeptide binding]; other site
272843003743	CoA binding site [chemical binding]; other site
272843003744	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
272843003745	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843003746	motif II; other site
272843003747	ATP-dependent DNA helicase Rep; Region: rep; TIGR01074
272843003748	Part of AAA domain; Region: AAA_19; pfam13245
272843003749	Family description; Region: UvrD_C_2; pfam13538
272843003750	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5645
272843003751	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
272843003752	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
272843003753	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
272843003754	active site
272843003755	P-loop; other site
272843003756	phosphorylation site [posttranslational modification]
272843003757	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
272843003758	active site
272843003759	phosphorylation site [posttranslational modification]
272843003760	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
272843003761	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
272843003762	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
272843003763	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
272843003764	Mannitol repressor; Region: MtlR; pfam05068
272843003765	Predicted secreted acid phosphatase [General function prediction only]; Region: COG2503
272843003766	DNA polymerase I; Provisional; Region: PRK05755
272843003767	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
272843003768	active site
272843003769	metal binding site 1 [ion binding]; metal-binding site
272843003770	putative 5' ssDNA interaction site; other site
272843003771	metal binding site 3; metal-binding site
272843003772	metal binding site 2 [ion binding]; metal-binding site
272843003773	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
272843003774	putative DNA binding site [nucleotide binding]; other site
272843003775	putative metal binding site [ion binding]; other site
272843003776	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
272843003777	active site
272843003778	catalytic site [active]
272843003779	substrate binding site [chemical binding]; other site
272843003780	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
272843003781	active site
272843003782	DNA binding site [nucleotide binding]
272843003783	catalytic site [active]
272843003784	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
272843003785	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
272843003786	putative DNA-binding cleft [nucleotide binding]; other site
272843003787	putative DNA clevage site; other site
272843003788	molecular lever; other site
272843003789	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
272843003790	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
272843003791	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
272843003792	DNA binding site [nucleotide binding]
272843003793	active site
272843003794	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
272843003795	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
272843003796	putative transporter; Validated; Region: PRK03818
272843003797	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
272843003798	TrkA-C domain; Region: TrkA_C; pfam02080
272843003799	TrkA-C domain; Region: TrkA_C; pfam02080
272843003800	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
272843003801	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
272843003802	ABC transporter transmembrane region 2; Region: ABC_membrane_2; pfam06472
272843003803	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
272843003804	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
272843003805	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
272843003806	active site
272843003807	substrate binding site [chemical binding]; other site
272843003808	metal binding site [ion binding]; metal-binding site
272843003809	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3021
272843003810	putative catalytic site [active]
272843003811	putative metal binding site [ion binding]; other site
272843003812	putative phosphate binding site [ion binding]; other site
272843003813	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
272843003814	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
272843003815	intersubunit interface [polypeptide binding]; other site
272843003816	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
272843003817	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
272843003818	dimer interface [polypeptide binding]; other site
272843003819	ABC-ATPase subunit  interface; other site
272843003820	putative PBP binding regions; other site
272843003821	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
272843003822	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
272843003823	Walker A/P-loop; other site
272843003824	ATP binding site [chemical binding]; other site
272843003825	Q-loop/lid; other site
272843003826	ABC transporter signature motif; other site
272843003827	Walker B; other site
272843003828	D-loop; other site
272843003829	H-loop/switch region; other site
272843003830	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
272843003831	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
272843003832	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843003833	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
272843003834	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
272843003835	dimerization interface [polypeptide binding]; other site
272843003836	ATP binding site [chemical binding]; other site
272843003837	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
272843003838	dimerization interface [polypeptide binding]; other site
272843003839	ATP binding site [chemical binding]; other site
272843003840	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
272843003841	putative active site [active]
272843003842	catalytic triad [active]
272843003843	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
272843003844	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
272843003845	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
272843003846	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
272843003847	FMN binding site [chemical binding]; other site
272843003848	active site
272843003849	catalytic residues [active]
272843003850	substrate binding site [chemical binding]; other site
272843003851	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
272843003852	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843003853	S-adenosylmethionine binding site [chemical binding]; other site
272843003854	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
272843003855	Na binding site [ion binding]; other site
272843003856	Predicted membrane protein [Function unknown]; Region: COG3924
272843003857	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
272843003858	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
272843003859	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
272843003860	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
272843003861	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
272843003862	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
272843003863	carboxyltransferase (CT) interaction site; other site
272843003864	biotinylation site [posttranslational modification]; other site
272843003865	Dehydroquinase class II; Region: DHquinase_II; pfam01220
272843003866	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
272843003867	active site
272843003868	trimer interface [polypeptide binding]; other site
272843003869	dimer interface [polypeptide binding]; other site
272843003870	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
272843003871	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
272843003872	active site
272843003873	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
272843003874	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
272843003875	substrate binding site [chemical binding]; other site
272843003876	oxyanion hole (OAH) forming residues; other site
272843003877	trimer interface [polypeptide binding]; other site
272843003878	Predicted membrane protein [Function unknown]; Region: COG4325
272843003879	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
272843003880	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
272843003881	dimer interface [polypeptide binding]; other site
272843003882	motif 1; other site
272843003883	active site
272843003884	motif 2; other site
272843003885	motif 3; other site
272843003886	Glutaredoxin-related protein [Posttranslational modification, protein turnover, chaperones]; Region: COG4545
272843003887	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
272843003888	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
272843003889	putative C-terminal domain interface [polypeptide binding]; other site
272843003890	putative GSH binding site (G-site) [chemical binding]; other site
272843003891	putative dimer interface [polypeptide binding]; other site
272843003892	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
272843003893	dimer interface [polypeptide binding]; other site
272843003894	N-terminal domain interface [polypeptide binding]; other site
272843003895	putative substrate binding pocket (H-site) [chemical binding]; other site
272843003896	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
272843003897	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
272843003898	Aspartase; Region: Aspartase; cd01357
272843003899	active sites [active]
272843003900	tetramer interface [polypeptide binding]; other site
272843003901	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
272843003902	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
272843003903	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
272843003904	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
272843003905	oligomerisation interface [polypeptide binding]; other site
272843003906	mobile loop; other site
272843003907	roof hairpin; other site
272843003908	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
272843003909	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
272843003910	ring oligomerisation interface [polypeptide binding]; other site
272843003911	ATP/Mg binding site [chemical binding]; other site
272843003912	stacking interactions; other site
272843003913	hinge regions; other site
272843003914	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
272843003915	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
272843003916	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
272843003917	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843003918	putative PBP binding loops; other site
272843003919	ABC-ATPase subunit interface; other site
272843003920	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
272843003921	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843003922	Walker A/P-loop; other site
272843003923	ATP binding site [chemical binding]; other site
272843003924	Q-loop/lid; other site
272843003925	ABC transporter signature motif; other site
272843003926	Walker B; other site
272843003927	D-loop; other site
272843003928	H-loop/switch region; other site
272843003929	molybdenum transport protein ModD; Provisional; Region: PRK06096
272843003930	ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport. In general, QPRTases are part of the de novo synthesis pathway of NAD in both prokaryotes and...; Region: modD_like; cd01573
272843003931	dimerization interface [polypeptide binding]; other site
272843003932	active site
272843003933	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
272843003934	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
272843003935	ATP binding site [chemical binding]; other site
272843003936	Mg++ binding site [ion binding]; other site
272843003937	motif III; other site
272843003938	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843003939	nucleotide binding region [chemical binding]; other site
272843003940	ATP-binding site [chemical binding]; other site
272843003941	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
272843003942	putative RNA binding site [nucleotide binding]; other site
272843003943	Lipoprotein NlpI, contains TPR repeats [General function prediction only]; Region: NlpI; COG4785
272843003944	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
272843003945	binding surface
272843003946	TPR motif; other site
272843003947	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
272843003948	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
272843003949	RNase E interface [polypeptide binding]; other site
272843003950	trimer interface [polypeptide binding]; other site
272843003951	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
272843003952	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
272843003953	RNase E interface [polypeptide binding]; other site
272843003954	trimer interface [polypeptide binding]; other site
272843003955	active site
272843003956	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
272843003957	putative nucleic acid binding region [nucleotide binding]; other site
272843003958	G-X-X-G motif; other site
272843003959	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
272843003960	RNA binding site [nucleotide binding]; other site
272843003961	domain interface; other site
272843003962	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
272843003963	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
272843003964	HIGH motif; other site
272843003965	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
272843003966	active site
272843003967	KMSKS motif; other site
272843003968	Mannosyltransferase OCH1 and related enzymes [Cell envelope biogenesis, outer membrane]; Region: OCH1; COG3774
272843003969	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
272843003970	acetylornithine deacetylase; Provisional; Region: PRK05111
272843003971	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
272843003972	metal binding site [ion binding]; metal-binding site
272843003973	putative dimer interface [polypeptide binding]; other site
272843003974	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
272843003975	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
272843003976	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
272843003977	nucleotide binding site [chemical binding]; other site
272843003978	N-acetyl-L-glutamate binding site [chemical binding]; other site
272843003979	argininosuccinate lyase; Provisional; Region: PRK04833
272843003980	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
272843003981	active sites [active]
272843003982	tetramer interface [polypeptide binding]; other site
272843003983	Domain of unknown function (DUF4415); Region: DUF4415; pfam14384
272843003984	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09638
272843003985	CRISPR/Cas system-associated protein Cas1; Region: Cas1_II; cd09720
272843003986	Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms]; Region: COG3513
272843003987	CRISPR/Cas system-associated protein Cas9; Region: Csn1; cd09643
272843003988	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
272843003989	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
272843003990	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
272843003991	ArsC family; Region: ArsC; pfam03960
272843003992	catalytic residues [active]
272843003993	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
272843003994	Domain of unknown function DUF20; Region: UPF0118; pfam01594
272843003995	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
272843003996	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
272843003997	GAF domain; Region: GAF_2; pfam13185
272843003998	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
272843003999	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
272843004000	HlyD family secretion protein; Region: HlyD_3; pfam13437
272843004001	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
272843004002	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
272843004003	Cell division protein [Cell division and chromosome partitioning]; Region: FtsN; COG3087
272843004004	Sporulation related domain; Region: SPOR; pfam05036
272843004005	primosome assembly protein PriA; Validated; Region: PRK05580
272843004006	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843004007	ATP binding site [chemical binding]; other site
272843004008	putative Mg++ binding site [ion binding]; other site
272843004009	helicase superfamily c-terminal domain; Region: HELICc; smart00490
272843004010	ATP-binding site [chemical binding]; other site
272843004011	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
272843004012	putative ADP-binding pocket [chemical binding]; other site
272843004013	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
272843004014	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
272843004015	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
272843004016	Ligand binding site; other site
272843004017	metal-binding site
272843004018	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
272843004019	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
272843004020	active site
272843004021	Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG3306
272843004022	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
272843004023	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
272843004024	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
272843004025	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
272843004026	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
272843004027	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
272843004028	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
272843004029	DNA binding site [nucleotide binding]
272843004030	catalytic residue [active]
272843004031	H2TH interface [polypeptide binding]; other site
272843004032	putative catalytic residues [active]
272843004033	turnover-facilitating residue; other site
272843004034	intercalation triad [nucleotide binding]; other site
272843004035	8OG recognition residue [nucleotide binding]; other site
272843004036	putative reading head residues; other site
272843004037	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
272843004038	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
272843004039	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
272843004040	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
272843004041	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
272843004042	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843004043	Walker A/P-loop; other site
272843004044	ATP binding site [chemical binding]; other site
272843004045	Q-loop/lid; other site
272843004046	ABC transporter signature motif; other site
272843004047	Walker B; other site
272843004048	D-loop; other site
272843004049	H-loop/switch region; other site
272843004050	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
272843004051	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
272843004052	ABC-ATPase subunit  interface; other site
272843004053	dimer interface [polypeptide binding]; other site
272843004054	putative PBP binding regions; other site
272843004055	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
272843004056	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
272843004057	putative ligand binding residues [chemical binding]; other site
272843004058	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
272843004059	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
272843004060	hypothetical protein; Reviewed; Region: PRK00024
272843004061	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
272843004062	MPN+ (JAMM) motif; other site
272843004063	Zinc-binding site [ion binding]; other site
272843004064	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
272843004065	Flavoprotein; Region: Flavoprotein; pfam02441
272843004066	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
272843004067	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
272843004068	trimer interface [polypeptide binding]; other site
272843004069	active site
272843004070	division inhibitor protein; Provisional; Region: slmA; PRK09480
272843004071	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
272843004072	hypothetical protein; Provisional; Region: PRK04966
272843004073	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
272843004074	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
272843004075	ligand binding site [chemical binding]; other site
272843004076	flexible hinge region; other site
272843004077	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
272843004078	putative switch regulator; other site
272843004079	non-specific DNA interactions [nucleotide binding]; other site
272843004080	DNA binding site [nucleotide binding]
272843004081	sequence specific DNA binding site [nucleotide binding]; other site
272843004082	putative cAMP binding site [chemical binding]; other site
272843004083	Methyltransferase domain; Region: Methyltransf_31; pfam13847
272843004084	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843004085	S-adenosylmethionine binding site [chemical binding]; other site
272843004086	Recombinational DNA repair ATPase (RecF pathway) [DNA replication, recombination, and repair]; Region: RecF; COG1195
272843004087	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843004088	Walker A/P-loop; other site
272843004089	ATP binding site [chemical binding]; other site
272843004090	Q-loop/lid; other site
272843004091	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843004092	ABC transporter signature motif; other site
272843004093	Walker B; other site
272843004094	D-loop; other site
272843004095	H-loop/switch region; other site
272843004096	DNA polymerase III subunit beta; Validated; Region: PRK05643
272843004097	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
272843004098	putative DNA binding surface [nucleotide binding]; other site
272843004099	dimer interface [polypeptide binding]; other site
272843004100	beta-clamp/clamp loader binding surface; other site
272843004101	beta-clamp/translesion DNA polymerase binding surface; other site
272843004102	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
272843004103	DnaA N-terminal domain; Region: DnaA_N; pfam11638
272843004104	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843004105	Walker A motif; other site
272843004106	ATP binding site [chemical binding]; other site
272843004107	Walker B motif; other site
272843004108	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
272843004109	arginine finger; other site
272843004110	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
272843004111	DnaA box-binding interface [nucleotide binding]; other site
272843004112	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
272843004113	ribonuclease P; Reviewed; Region: rnpA; PRK01732
272843004114	hypothetical protein; Validated; Region: PRK00041
272843004115	membrane protein insertase; Provisional; Region: PRK01318
272843004116	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
272843004117	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
272843004118	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
272843004119	trmE is a tRNA modification GTPase; Region: trmE; cd04164
272843004120	G1 box; other site
272843004121	GTP/Mg2+ binding site [chemical binding]; other site
272843004122	Switch I region; other site
272843004123	G2 box; other site
272843004124	Switch II region; other site
272843004125	G3 box; other site
272843004126	G4 box; other site
272843004127	G5 box; other site
272843004128	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
272843004129	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
272843004130	transmembrane helices; other site
272843004131	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
272843004132	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
272843004133	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
272843004134	UbiA prenyltransferase family; Region: UbiA; pfam01040
272843004135	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
272843004136	homodimer interaction site [polypeptide binding]; other site
272843004137	cofactor binding site; other site
272843004138	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
272843004139	Uncharacterized integral membrane protein [Function unknown]; Region: COG3739
272843004140	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
272843004141	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
272843004142	G1 box; other site
272843004143	putative GEF interaction site [polypeptide binding]; other site
272843004144	GTP/Mg2+ binding site [chemical binding]; other site
272843004145	Switch I region; other site
272843004146	G2 box; other site
272843004147	G3 box; other site
272843004148	Switch II region; other site
272843004149	G4 box; other site
272843004150	G5 box; other site
272843004151	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
272843004152	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
272843004153	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
272843004154	glutamine synthetase; Provisional; Region: glnA; PRK09469
272843004155	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
272843004156	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
272843004157	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; cl01604
272843004158	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
272843004159	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
272843004160	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
272843004161	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
272843004162	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
272843004163	dimer interface [polypeptide binding]; other site
272843004164	ssDNA binding site [nucleotide binding]; other site
272843004165	tetramer (dimer of dimers) interface [polypeptide binding]; other site
272843004166	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
272843004167	LexA repressor; Validated; Region: PRK00215
272843004168	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
272843004169	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
272843004170	Catalytic site [active]
272843004171	Glycerol-3-phosphate O-acyltransferase [Lipid metabolism]; Region: PlsB; COG2937
272843004172	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
272843004173	putative acyl-acceptor binding pocket; other site
272843004174	signal recognition particle protein; Provisional; Region: PRK10867
272843004175	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
272843004176	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
272843004177	P loop; other site
272843004178	GTP binding site [chemical binding]; other site
272843004179	Signal peptide binding domain; Region: SRP_SPB; pfam02978
272843004180	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
272843004181	Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536
272843004182	Domain of unknown function DUF21; Region: DUF21; pfam01595
272843004183	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
272843004184	Transporter associated domain; Region: CorC_HlyC; smart01091
272843004185	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
272843004186	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
272843004187	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
272843004188	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
272843004189	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
272843004190	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
272843004191	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
272843004192	dimer interface [polypeptide binding]; other site
272843004193	substrate binding site [chemical binding]; other site
272843004194	metal binding sites [ion binding]; metal-binding site
272843004195	aromatic amino acid transport protein; Region: araaP; TIGR00837
272843004196	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
272843004197	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
272843004198	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
272843004199	active site
272843004200	metal binding site [ion binding]; metal-binding site
272843004201	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
272843004202	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843004203	S-adenosylmethionine binding site [chemical binding]; other site
272843004204	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
272843004205	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
272843004206	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
272843004207	Y-family of DNA polymerases; Region: PolY; cl12025
272843004208	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
272843004209	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
272843004210	trimer interface [polypeptide binding]; other site
272843004211	active site
272843004212	substrate binding site [chemical binding]; other site
272843004213	CoA binding site [chemical binding]; other site
272843004214	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
272843004215	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
272843004216	NAD binding site [chemical binding]; other site
272843004217	dimerization interface [polypeptide binding]; other site
272843004218	product binding site; other site
272843004219	substrate binding site [chemical binding]; other site
272843004220	zinc binding site [ion binding]; other site
272843004221	catalytic residues [active]
272843004222	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
272843004223	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
272843004224	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843004225	homodimer interface [polypeptide binding]; other site
272843004226	catalytic residue [active]
272843004227	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
272843004228	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843004229	active site
272843004230	motif I; other site
272843004231	motif II; other site
272843004232	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
272843004233	putative active site pocket [active]
272843004234	4-fold oligomerization interface [polypeptide binding]; other site
272843004235	metal binding residues [ion binding]; metal-binding site
272843004236	3-fold/trimer interface [polypeptide binding]; other site
272843004237	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
272843004238	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
272843004239	putative active site [active]
272843004240	oxyanion strand; other site
272843004241	catalytic triad [active]
272843004242	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
272843004243	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
272843004244	catalytic residues [active]
272843004245	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
272843004246	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
272843004247	substrate binding site [chemical binding]; other site
272843004248	glutamase interaction surface [polypeptide binding]; other site
272843004249	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
272843004250	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
272843004251	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
272843004252	metal binding site [ion binding]; metal-binding site
272843004253	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
272843004254	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843004255	active site
272843004256	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
272843004257	SurA N-terminal domain; Region: SurA_N; pfam09312
272843004258	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
272843004259	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
272843004260	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
272843004261	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
272843004262	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
272843004263	active site
272843004264	metal binding site [ion binding]; metal-binding site
272843004265	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
272843004266	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
272843004267	MerT mercuric transport protein; Region: MerT; cl03578
272843004268	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
272843004269	metal-binding site [ion binding]
272843004270	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
272843004271	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
272843004272	HIGH motif; other site
272843004273	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
272843004274	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
272843004275	active site
272843004276	KMSKS motif; other site
272843004277	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
272843004278	tRNA binding surface [nucleotide binding]; other site
272843004279	Rare lipoprotein B [Cell envelope biogenesis, outer membrane]; Region: RlpB; COG2980
272843004280	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
272843004281	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
272843004282	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
272843004283	active site
272843004284	8-oxo-dGMP binding site [chemical binding]; other site
272843004285	nudix motif; other site
272843004286	metal binding site [ion binding]; metal-binding site
272843004287	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
272843004288	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
272843004289	SEC-C motif; Region: SEC-C; pfam02810
272843004290	Protein of unknown function (DUF2547); Region: DUF2547; pfam10818
272843004291	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4701
272843004292	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
272843004293	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
272843004294	active site
272843004295	dimer interface [polypeptide binding]; other site
272843004296	metal binding site [ion binding]; metal-binding site
272843004297	shikimate kinase; Reviewed; Region: aroK; PRK00131
272843004298	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
272843004299	ADP binding site [chemical binding]; other site
272843004300	magnesium binding site [ion binding]; other site
272843004301	putative shikimate binding site; other site
272843004302	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
272843004303	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
272843004304	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
272843004305	Pilus assembly protein, PilP; Region: PilP; pfam04351
272843004306	Competence protein A; Region: Competence_A; pfam11104
272843004307	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
272843004308	Transglycosylase; Region: Transgly; pfam00912
272843004309	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
272843004310	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
272843004311	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
272843004312	DNA-binding site [nucleotide binding]; DNA binding site
272843004313	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
272843004314	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843004315	homodimer interface [polypeptide binding]; other site
272843004316	catalytic residue [active]
272843004317	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
272843004318	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
272843004319	active site
272843004320	multimer interface [polypeptide binding]; other site
272843004321	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
272843004322	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
272843004323	predicted active site [active]
272843004324	catalytic triad [active]
272843004325	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
272843004326	glutathione reductase; Validated; Region: PRK06116
272843004327	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
272843004328	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
272843004329	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
272843004330	thymidine kinase; Provisional; Region: PRK04296
272843004331	UGMP family protein; Validated; Region: PRK09604
272843004332	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
272843004333	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
272843004334	DNA primase; Validated; Region: dnaG; PRK05667
272843004335	CHC2 zinc finger; Region: zf-CHC2; pfam01807
272843004336	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
272843004337	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
272843004338	active site
272843004339	metal binding site [ion binding]; metal-binding site
272843004340	interdomain interaction site; other site
272843004341	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
272843004342	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
272843004343	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
272843004344	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
272843004345	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
272843004346	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
272843004347	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
272843004348	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
272843004349	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
272843004350	DNA binding residues [nucleotide binding]
272843004351	transketolase; Reviewed; Region: PRK12753
272843004352	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
272843004353	TPP-binding site [chemical binding]; other site
272843004354	dimer interface [polypeptide binding]; other site
272843004355	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
272843004356	PYR/PP interface [polypeptide binding]; other site
272843004357	dimer interface [polypeptide binding]; other site
272843004358	TPP binding site [chemical binding]; other site
272843004359	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
272843004360	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
272843004361	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843004362	active site
272843004363	motif I; other site
272843004364	motif II; other site
272843004365	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843004366	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
272843004367	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
272843004368	intersubunit interface [polypeptide binding]; other site
272843004369	active site
272843004370	Zn2+ binding site [ion binding]; other site
272843004371	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
272843004372	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
272843004373	AP (apurinic/apyrimidinic) site pocket; other site
272843004374	DNA interaction; other site
272843004375	Metal-binding active site; metal-binding site
272843004376	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
272843004377	active site
272843004378	dimer interface [polypeptide binding]; other site
272843004379	magnesium binding site [ion binding]; other site
272843004380	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
272843004381	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
272843004382	putative N- and C-terminal domain interface [polypeptide binding]; other site
272843004383	putative active site [active]
272843004384	MgATP binding site [chemical binding]; other site
272843004385	catalytic site [active]
272843004386	metal binding site [ion binding]; metal-binding site
272843004387	putative xylulose binding site [chemical binding]; other site
272843004388	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
272843004389	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_6; cd06315
272843004390	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
272843004391	putative ligand binding site [chemical binding]; other site
272843004392	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
272843004393	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
272843004394	TM-ABC transporter signature motif; other site
272843004395	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
272843004396	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
272843004397	Walker A/P-loop; other site
272843004398	ATP binding site [chemical binding]; other site
272843004399	Q-loop/lid; other site
272843004400	ABC transporter signature motif; other site
272843004401	Walker B; other site
272843004402	D-loop; other site
272843004403	H-loop/switch region; other site
272843004404	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
272843004405	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
272843004406	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
272843004407	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; cl17274
272843004408	DctM-like transporters; Region: DctM; pfam06808
272843004409	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
272843004410	Domain of unknown function (DUF386); Region: DUF386; pfam04074
272843004411	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
272843004412	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
272843004413	Transcriptional regulator [Transcription]; Region: IclR; COG1414
272843004414	Bacterial transcriptional regulator; Region: IclR; pfam01614
272843004415	hypothetical protein; Provisional; Region: PRK05208
272843004416	metabolite-proton symporter; Region: 2A0106; TIGR00883
272843004417	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843004418	putative substrate translocation pore; other site
272843004419	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
272843004420	active site
272843004421	thiamine phosphate binding site [chemical binding]; other site
272843004422	pyrophosphate binding site [ion binding]; other site
272843004423	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
272843004424	dimer interface [polypeptide binding]; other site
272843004425	substrate binding site [chemical binding]; other site
272843004426	ATP binding site [chemical binding]; other site
272843004427	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
272843004428	substrate binding site [chemical binding]; other site
272843004429	multimerization interface [polypeptide binding]; other site
272843004430	ATP binding site [chemical binding]; other site
272843004431	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
272843004432	NMT1/THI5 like; Region: NMT1; pfam09084
272843004433	Putative transcription activator [Transcription]; Region: TenA; COG0819
272843004434	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
272843004435	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843004436	dimer interface [polypeptide binding]; other site
272843004437	conserved gate region; other site
272843004438	putative PBP binding loops; other site
272843004439	ABC-ATPase subunit interface; other site
272843004440	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
272843004441	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843004442	Walker A/P-loop; other site
272843004443	ATP binding site [chemical binding]; other site
272843004444	Q-loop/lid; other site
272843004445	ABC transporter signature motif; other site
272843004446	Walker B; other site
272843004447	D-loop; other site
272843004448	H-loop/switch region; other site
272843004449	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
272843004450	RmuC family; Region: RmuC; pfam02646
272843004451	Maf-like protein; Region: Maf; pfam02545
272843004452	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
272843004453	active site
272843004454	dimer interface [polypeptide binding]; other site
272843004455	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
272843004456	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
272843004457	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
272843004458	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
272843004459	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
272843004460	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
272843004461	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
272843004462	shikimate binding site; other site
272843004463	NAD(P) binding site [chemical binding]; other site
272843004464	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
272843004465	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
272843004466	putative N- and C-terminal domain interface [polypeptide binding]; other site
272843004467	putative active site [active]
272843004468	putative MgATP binding site [chemical binding]; other site
272843004469	catalytic site [active]
272843004470	metal binding site [ion binding]; metal-binding site
272843004471	putative carbohydrate binding site [chemical binding]; other site
272843004472	transcriptional regulator LsrR; Provisional; Region: PRK15418
272843004473	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
272843004474	non-specific DNA interactions [nucleotide binding]; other site
272843004475	DNA binding site [nucleotide binding]
272843004476	sequence specific DNA binding site [nucleotide binding]; other site
272843004477	putative cAMP binding site [chemical binding]; other site
272843004478	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
272843004479	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
272843004480	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
272843004481	Walker A/P-loop; other site
272843004482	ATP binding site [chemical binding]; other site
272843004483	Q-loop/lid; other site
272843004484	ABC transporter signature motif; other site
272843004485	Walker B; other site
272843004486	D-loop; other site
272843004487	H-loop/switch region; other site
272843004488	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
272843004489	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
272843004490	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
272843004491	TM-ABC transporter signature motif; other site
272843004492	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
272843004493	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
272843004494	TM-ABC transporter signature motif; other site
272843004495	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
272843004496	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
272843004497	ligand binding site [chemical binding]; other site
272843004498	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
272843004499	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
272843004500	putative active site; other site
272843004501	catalytic residue [active]
272843004502	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
272843004503	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
272843004504	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
272843004505	substrate binding site [chemical binding]; other site
272843004506	hexamer interface [polypeptide binding]; other site
272843004507	metal binding site [ion binding]; metal-binding site
272843004508	Predicted permeases [General function prediction only]; Region: RarD; COG2962
272843004509	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
272843004510	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843004511	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
272843004512	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
272843004513	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
272843004514	putative dimerization interface [polypeptide binding]; other site
272843004515	ketol-acid reductoisomerase; Validated; Region: PRK05225
272843004516	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
272843004517	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
272843004518	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
272843004519	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
272843004520	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
272843004521	homodimer interface [polypeptide binding]; other site
272843004522	metal binding site [ion binding]; metal-binding site
272843004523	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
272843004524	homodimer interface [polypeptide binding]; other site
272843004525	active site
272843004526	putative chemical substrate binding site [chemical binding]; other site
272843004527	metal binding site [ion binding]; metal-binding site
272843004528	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
272843004529	Ligand Binding Site [chemical binding]; other site
272843004530	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
272843004531	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
272843004532	motif 1; other site
272843004533	active site
272843004534	motif 2; other site
272843004535	motif 3; other site
272843004536	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
272843004537	DHHA1 domain; Region: DHHA1; pfam02272
272843004538	carbon storage regulator; Provisional; Region: PRK01712
272843004539	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
272843004540	active site
272843004541	tetramer interface; other site
272843004542	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
272843004543	dimerization interface [polypeptide binding]; other site
272843004544	DNA binding site [nucleotide binding]
272843004545	corepressor binding sites; other site
272843004546	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
272843004547	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
272843004548	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
272843004549	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
272843004550	Nucleoside recognition; Region: Gate; pfam07670
272843004551	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
272843004552	Predicted membrane protein [Function unknown]; Region: COG2364
272843004553	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
272843004554	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
272843004555	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
272843004556	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
272843004557	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
272843004558	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
272843004559	RimM N-terminal domain; Region: RimM; pfam01782
272843004560	PRC-barrel domain; Region: PRC; pfam05239
272843004561	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
272843004562	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
272843004563	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
272843004564	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
272843004565	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
272843004566	putative metal binding site [ion binding]; other site
272843004567	dimer interface [polypeptide binding]; other site
272843004568	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
272843004569	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
272843004570	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
272843004571	Walker A/P-loop; other site
272843004572	ATP binding site [chemical binding]; other site
272843004573	Q-loop/lid; other site
272843004574	ABC transporter signature motif; other site
272843004575	Walker B; other site
272843004576	D-loop; other site
272843004577	H-loop/switch region; other site
272843004578	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
272843004579	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
272843004580	putative active site [active]
272843004581	3-deoxy-D-manno-octulosonic-acid kinase; Reviewed; Region: PRK01723
272843004582	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
272843004583	active site
272843004584	ATP binding site [chemical binding]; other site
272843004585	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
272843004586	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
272843004587	active site
272843004588	(T/H)XGH motif; other site
272843004589	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
272843004590	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
272843004591	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
272843004592	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
272843004593	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
272843004594	putative metal binding site; other site
272843004595	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
272843004596	Metal binding protein HemV-2.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: HemV-2; cd01147
272843004597	putative metal binding site [ion binding]; other site
272843004598	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
272843004599	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
272843004600	ABC-ATPase subunit  interface; other site
272843004601	dimer interface [polypeptide binding]; other site
272843004602	putative PBP binding regions; other site
272843004603	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
272843004604	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
272843004605	Walker A/P-loop; other site
272843004606	ATP binding site [chemical binding]; other site
272843004607	Q-loop/lid; other site
272843004608	ABC transporter signature motif; other site
272843004609	Walker B; other site
272843004610	D-loop; other site
272843004611	H-loop/switch region; other site
272843004612	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
272843004613	Methyltransferase domain; Region: Methyltransf_18; pfam12847
272843004614	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
272843004615	triosephosphate isomerase; Provisional; Region: PRK14567
272843004616	substrate binding site [chemical binding]; other site
272843004617	dimer interface [polypeptide binding]; other site
272843004618	catalytic triad [active]
272843004619	ornithine cyclodeaminase; Validated; Region: PRK07589
272843004620	hypothetical protein; Validated; Region: PRK05090
272843004621	YGGT family; Region: YGGT; pfam02325
272843004622	YGGT family; Region: YGGT; pfam02325
272843004623	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
272843004624	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
272843004625	Cl binding site [ion binding]; other site
272843004626	oligomer interface [polypeptide binding]; other site
272843004627	hypothetical protein; Provisional; Region: PRK11702
272843004628	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
272843004629	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
272843004630	adenine DNA glycosylase; Provisional; Region: PRK10880
272843004631	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
272843004632	minor groove reading motif; other site
272843004633	helix-hairpin-helix signature motif; other site
272843004634	substrate binding pocket [chemical binding]; other site
272843004635	active site
272843004636	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
272843004637	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
272843004638	DNA binding and oxoG recognition site [nucleotide binding]
272843004639	oxidative damage protection protein; Provisional; Region: PRK05408
272843004640	murein transglycosylase C; Provisional; Region: mltC; PRK11671
272843004641	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
272843004642	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
272843004643	N-acetyl-D-glucosamine binding site [chemical binding]; other site
272843004644	catalytic residue [active]
272843004645	O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315
272843004646	Leucine carboxyl methyltransferase; Region: LCM; pfam04072
272843004647	Uncharacterized lipoprotein [Cell envelope biogenesis, outer membrane]; Region: COG3056
272843004648	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
272843004649	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
272843004650	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
272843004651	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
272843004652	ligand binding site [chemical binding]; other site
272843004653	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
272843004654	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
272843004655	Walker A/P-loop; other site
272843004656	ATP binding site [chemical binding]; other site
272843004657	Q-loop/lid; other site
272843004658	ABC transporter signature motif; other site
272843004659	Walker B; other site
272843004660	D-loop; other site
272843004661	H-loop/switch region; other site
272843004662	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
272843004663	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
272843004664	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
272843004665	TM-ABC transporter signature motif; other site
272843004666	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
272843004667	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
272843004668	E3 interaction surface; other site
272843004669	lipoyl attachment site [posttranslational modification]; other site
272843004670	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
272843004671	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
272843004672	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC [Energy production and conversion]; Region: NqrC; COG2869
272843004673	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
272843004674	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
272843004675	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
272843004676	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
272843004677	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
272843004678	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
272843004679	FAD binding pocket [chemical binding]; other site
272843004680	FAD binding motif [chemical binding]; other site
272843004681	phosphate binding motif [ion binding]; other site
272843004682	beta-alpha-beta structure motif; other site
272843004683	NAD binding pocket [chemical binding]; other site
272843004684	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
272843004685	ApbE family; Region: ApbE; pfam02424
272843004686	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2991
272843004687	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
272843004688	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
272843004689	Ligand Binding Site [chemical binding]; other site
272843004690	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
272843004691	regulatory protein UhpC; Provisional; Region: PRK11663
272843004692	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843004693	putative substrate translocation pore; other site
272843004694	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
272843004695	MASE1; Region: MASE1; pfam05231
272843004696	Histidine kinase; Region: HisKA_3; pfam07730
272843004697	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
272843004698	ATP binding site [chemical binding]; other site
272843004699	G-X-G motif; other site
272843004700	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
272843004701	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843004702	active site
272843004703	phosphorylation site [posttranslational modification]
272843004704	intermolecular recognition site; other site
272843004705	dimerization interface [polypeptide binding]; other site
272843004706	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
272843004707	DNA binding residues [nucleotide binding]
272843004708	dimerization interface [polypeptide binding]; other site
272843004709	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
272843004710	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843004711	putative substrate translocation pore; other site
272843004712	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
272843004713	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
272843004714	NADP binding site [chemical binding]; other site
272843004715	homopentamer interface [polypeptide binding]; other site
272843004716	substrate binding site [chemical binding]; other site
272843004717	active site
272843004718	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
272843004719	intersubunit interface [polypeptide binding]; other site
272843004720	active site
272843004721	catalytic residue [active]
272843004722	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
272843004723	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
272843004724	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
272843004725	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
272843004726	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
272843004727	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
272843004728	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
272843004729	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
272843004730	dimerization interface [polypeptide binding]; other site
272843004731	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
272843004732	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
272843004733	catalytic triad [active]
272843004734	dimer interface [polypeptide binding]; other site
272843004735	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
272843004736	hypothetical protein; Provisional; Region: PRK02119
272843004737	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
272843004738	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
272843004739	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
272843004740	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
272843004741	YheO-like PAS domain; Region: PAS_6; pfam08348
272843004742	HTH domain; Region: HTH_22; pfam13309
272843004743	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
272843004744	sulfur relay protein TusC/DsrF; Region: sulf_tusC_dsrF; TIGR03010
272843004745	Uncharacterized conserved protein involved in oxidation of intracellular sulfur [Inorganic ion transport and metabolism]; Region: DsrH; COG2168
272843004746	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
272843004747	S17 interaction site [polypeptide binding]; other site
272843004748	S8 interaction site; other site
272843004749	16S rRNA interaction site [nucleotide binding]; other site
272843004750	streptomycin interaction site [chemical binding]; other site
272843004751	23S rRNA interaction site [nucleotide binding]; other site
272843004752	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
272843004753	30S ribosomal protein S7; Validated; Region: PRK05302
272843004754	elongation factor G; Reviewed; Region: PRK00007
272843004755	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
272843004756	G1 box; other site
272843004757	putative GEF interaction site [polypeptide binding]; other site
272843004758	GTP/Mg2+ binding site [chemical binding]; other site
272843004759	Switch I region; other site
272843004760	G2 box; other site
272843004761	G3 box; other site
272843004762	Switch II region; other site
272843004763	G4 box; other site
272843004764	G5 box; other site
272843004765	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
272843004766	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
272843004767	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
272843004768	elongation factor Tu; Reviewed; Region: PRK00049
272843004769	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
272843004770	G1 box; other site
272843004771	GEF interaction site [polypeptide binding]; other site
272843004772	GTP/Mg2+ binding site [chemical binding]; other site
272843004773	Switch I region; other site
272843004774	G2 box; other site
272843004775	G3 box; other site
272843004776	Switch II region; other site
272843004777	G4 box; other site
272843004778	G5 box; other site
272843004779	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
272843004780	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
272843004781	Antibiotic Binding Site [chemical binding]; other site
272843004782	Predicted peptidase [General function prediction only]; Region: COG4099
272843004783	fructuronate transporter; Provisional; Region: PRK10034; cl15264
272843004784	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
272843004785	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
272843004786	putative NAD(P) binding site [chemical binding]; other site
272843004787	active site
272843004788	putative substrate binding site [chemical binding]; other site
272843004789	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
272843004790	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
272843004791	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
272843004792	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
272843004793	putative aldolase; Validated; Region: PRK08130
272843004794	intersubunit interface [polypeptide binding]; other site
272843004795	active site
272843004796	Zn2+ binding site [ion binding]; other site
272843004797	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
272843004798	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
272843004799	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
272843004800	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
272843004801	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
272843004802	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
272843004803	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
272843004804	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
272843004805	metal binding site [ion binding]; metal-binding site
272843004806	dimer interface [polypeptide binding]; other site
272843004807	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843004808	active site
272843004809	prolyl-tRNA synthetase; Provisional; Region: PRK09194
272843004810	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
272843004811	dimer interface [polypeptide binding]; other site
272843004812	motif 1; other site
272843004813	active site
272843004814	motif 2; other site
272843004815	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
272843004816	putative deacylase active site [active]
272843004817	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
272843004818	active site
272843004819	motif 3; other site
272843004820	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
272843004821	anticodon binding site; other site
272843004822	D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_1; cd07809
272843004823	N- and C-terminal domain interface [polypeptide binding]; other site
272843004824	D-xylulose kinase; Region: XylB; TIGR01312
272843004825	active site
272843004826	MgATP binding site [chemical binding]; other site
272843004827	catalytic site [active]
272843004828	metal binding site [ion binding]; metal-binding site
272843004829	xylulose binding site [chemical binding]; other site
272843004830	putative homodimer interface [polypeptide binding]; other site
272843004831	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
272843004832	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
272843004833	substrate binding site [chemical binding]; other site
272843004834	ATP binding site [chemical binding]; other site
272843004835	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
272843004836	intersubunit interface [polypeptide binding]; other site
272843004837	active site
272843004838	zinc binding site [ion binding]; other site
272843004839	Na+ binding site [ion binding]; other site
272843004840	Protein of unknown function (DUF1498); Region: DUF1498; pfam07385
272843004841	fructokinase; Reviewed; Region: PRK09557
272843004842	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
272843004843	nucleotide binding site [chemical binding]; other site
272843004844	Acetokinase family; Region: Acetate_kinase; cl17229
272843004845	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
272843004846	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843004847	active site
272843004848	phosphorylation site [posttranslational modification]
272843004849	intermolecular recognition site; other site
272843004850	dimerization interface [polypeptide binding]; other site
272843004851	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
272843004852	DNA binding site [nucleotide binding]
272843004853	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
272843004854	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
272843004855	putative ligand binding site [chemical binding]; other site
272843004856	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
272843004857	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
272843004858	TM-ABC transporter signature motif; other site
272843004859	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
272843004860	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
272843004861	Walker A/P-loop; other site
272843004862	ATP binding site [chemical binding]; other site
272843004863	Q-loop/lid; other site
272843004864	ABC transporter signature motif; other site
272843004865	Walker B; other site
272843004866	D-loop; other site
272843004867	H-loop/switch region; other site
272843004868	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
272843004869	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
272843004870	dimerization interface [polypeptide binding]; other site
272843004871	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
272843004872	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
272843004873	dimer interface [polypeptide binding]; other site
272843004874	phosphorylation site [posttranslational modification]
272843004875	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843004876	ATP binding site [chemical binding]; other site
272843004877	Mg2+ binding site [ion binding]; other site
272843004878	G-X-G motif; other site
272843004879	Response regulator receiver domain; Region: Response_reg; pfam00072
272843004880	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843004881	active site
272843004882	phosphorylation site [posttranslational modification]
272843004883	intermolecular recognition site; other site
272843004884	dimerization interface [polypeptide binding]; other site
272843004885	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
272843004886	agmatinase; Region: agmatinase; TIGR01230
272843004887	oligomer interface [polypeptide binding]; other site
272843004888	putative active site [active]
272843004889	Mn binding site [ion binding]; other site
272843004890	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
272843004891	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
272843004892	dimer interface [polypeptide binding]; other site
272843004893	active site
272843004894	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
272843004895	catalytic residues [active]
272843004896	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
272843004897	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
272843004898	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
272843004899	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
272843004900	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
272843004901	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK01792
272843004902	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
272843004903	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
272843004904	non-specific DNA binding site [nucleotide binding]; other site
272843004905	salt bridge; other site
272843004906	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
272843004907	sequence-specific DNA binding site [nucleotide binding]; other site
272843004908	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
272843004909	active site
272843004910	(T/H)XGH motif; other site
272843004911	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
272843004912	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
272843004913	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
272843004914	active site
272843004915	metal binding site [ion binding]; metal-binding site
272843004916	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
272843004917	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
272843004918	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
272843004919	alphaNTD homodimer interface [polypeptide binding]; other site
272843004920	alphaNTD - beta interaction site [polypeptide binding]; other site
272843004921	alphaNTD - beta' interaction site [polypeptide binding]; other site
272843004922	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
272843004923	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
272843004924	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
272843004925	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
272843004926	RNA binding surface [nucleotide binding]; other site
272843004927	30S ribosomal protein S11; Validated; Region: PRK05309
272843004928	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
272843004929	30S ribosomal protein S13; Region: bact_S13; TIGR03631
272843004930	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
272843004931	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
272843004932	SecY translocase; Region: SecY; pfam00344
272843004933	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
272843004934	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
272843004935	23S rRNA binding site [nucleotide binding]; other site
272843004936	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
272843004937	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
272843004938	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
272843004939	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
272843004940	5S rRNA interface [nucleotide binding]; other site
272843004941	L27 interface [polypeptide binding]; other site
272843004942	23S rRNA interface [nucleotide binding]; other site
272843004943	L5 interface [polypeptide binding]; other site
272843004944	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
272843004945	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
272843004946	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
272843004947	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
272843004948	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
272843004949	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
272843004950	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
272843004951	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
272843004952	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
272843004953	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
272843004954	RNA binding site [nucleotide binding]; other site
272843004955	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
272843004956	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
272843004957	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
272843004958	23S rRNA interface [nucleotide binding]; other site
272843004959	putative translocon interaction site; other site
272843004960	signal recognition particle (SRP54) interaction site; other site
272843004961	L23 interface [polypeptide binding]; other site
272843004962	trigger factor interaction site; other site
272843004963	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
272843004964	23S rRNA interface [nucleotide binding]; other site
272843004965	5S rRNA interface [nucleotide binding]; other site
272843004966	putative antibiotic binding site [chemical binding]; other site
272843004967	L25 interface [polypeptide binding]; other site
272843004968	L27 interface [polypeptide binding]; other site
272843004969	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
272843004970	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
272843004971	G-X-X-G motif; other site
272843004972	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
272843004973	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
272843004974	protein-rRNA interface [nucleotide binding]; other site
272843004975	putative translocon binding site; other site
272843004976	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
272843004977	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
272843004978	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
272843004979	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
272843004980	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
272843004981	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
272843004982	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
272843004983	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
272843004984	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
272843004985	ClC chloride channel family. These protein sequences, closely related to the ClC Eric family, are putative halogen ion (Cl-, Br- and I-) transport proteins found in eubacteria. They belong to the ClC superfamily of chloride ion channels, which share a...; Region: EriC_like; cd01034
272843004986	putative ion selectivity filter; other site
272843004987	putative pore gating glutamate residue; other site
272843004988	putative H+/Cl- coupling transport residue; other site
272843004989	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
272843004990	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
272843004991	FMN binding site [chemical binding]; other site
272843004992	active site
272843004993	catalytic residues [active]
272843004994	substrate binding site [chemical binding]; other site
272843004995	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
272843004996	aromatic amino acid transport protein; Region: araaP; TIGR00837
272843004997	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
272843004998	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
272843004999	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
272843005000	catalytic residue [active]
272843005001	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
272843005002	oxaloacetate decarboxylase; Provisional; Region: PRK14040
272843005003	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
272843005004	active site
272843005005	catalytic residues [active]
272843005006	metal binding site [ion binding]; metal-binding site
272843005007	homodimer binding site [polypeptide binding]; other site
272843005008	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
272843005009	carboxyltransferase (CT) interaction site; other site
272843005010	biotinylation site [posttranslational modification]; other site
272843005011	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
272843005012	diaminopimelate decarboxylase; Region: lysA; TIGR01048
272843005013	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
272843005014	active site
272843005015	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
272843005016	substrate binding site [chemical binding]; other site
272843005017	catalytic residues [active]
272843005018	dimer interface [polypeptide binding]; other site
272843005019	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
272843005020	putative iron binding site [ion binding]; other site
272843005021	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
272843005022	dimerization interface [polypeptide binding]; other site
272843005023	substrate binding site [chemical binding]; other site
272843005024	active site
272843005025	calcium binding site [ion binding]; other site
272843005026	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
272843005027	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843005028	ATP binding site [chemical binding]; other site
272843005029	putative Mg++ binding site [ion binding]; other site
272843005030	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843005031	nucleotide binding region [chemical binding]; other site
272843005032	ATP-binding site [chemical binding]; other site
272843005033	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
272843005034	HRDC domain; Region: HRDC; pfam00570
272843005035	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
272843005036	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
272843005037	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
272843005038	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
272843005039	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
272843005040	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
272843005041	shikimate binding site; other site
272843005042	NAD(P) binding site [chemical binding]; other site
272843005043	serine acetyltransferase; Provisional; Region: cysE; PRK11132
272843005044	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
272843005045	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
272843005046	trimer interface [polypeptide binding]; other site
272843005047	active site
272843005048	substrate binding site [chemical binding]; other site
272843005049	CoA binding site [chemical binding]; other site
272843005050	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
272843005051	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
272843005052	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
272843005053	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
272843005054	SecA binding site; other site
272843005055	Preprotein binding site; other site
272843005056	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
272843005057	active site residue [active]
272843005058	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
272843005059	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
272843005060	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
272843005061	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843005062	Walker A motif; other site
272843005063	ATP binding site [chemical binding]; other site
272843005064	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
272843005065	active site residue [active]
272843005066	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
272843005067	rhomboid family protease GlpG; Region: rhombo_GlpG; TIGR04239
272843005068	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
272843005069	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
272843005070	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
272843005071	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
272843005072	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
272843005073	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
272843005074	Cysteine-rich domain; Region: CCG; pfam02754
272843005075	Cysteine-rich domain; Region: CCG; pfam02754
272843005076	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
272843005077	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
272843005078	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
272843005079	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
272843005080	glycerol-3-phosphate transporter; Region: glpT; TIGR00712
272843005081	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843005082	putative substrate translocation pore; other site
272843005083	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843005084	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
272843005085	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
272843005086	active site
272843005087	catalytic site [active]
272843005088	metal binding site [ion binding]; metal-binding site
272843005089	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
272843005090	amphipathic channel; other site
272843005091	Asn-Pro-Ala signature motifs; other site
272843005092	glycerol kinase; Provisional; Region: glpK; PRK00047
272843005093	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
272843005094	N- and C-terminal domain interface [polypeptide binding]; other site
272843005095	active site
272843005096	MgATP binding site [chemical binding]; other site
272843005097	catalytic site [active]
272843005098	metal binding site [ion binding]; metal-binding site
272843005099	glycerol binding site [chemical binding]; other site
272843005100	homotetramer interface [polypeptide binding]; other site
272843005101	homodimer interface [polypeptide binding]; other site
272843005102	FBP binding site [chemical binding]; other site
272843005103	protein IIAGlc interface [polypeptide binding]; other site
272843005104	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
272843005105	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
272843005106	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
272843005107	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
272843005108	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
272843005109	RNA binding site [nucleotide binding]; other site
272843005110	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
272843005111	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
272843005112	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
272843005113	Predicted esterase [General function prediction only]; Region: COG0627
272843005114	S-formylglutathione hydrolase; Region: PLN02442
272843005115	Predicted membrane protein [Function unknown]; Region: COG1584
272843005116	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
272843005117	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
272843005118	putative catalytic cysteine [active]
272843005119	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
272843005120	putative active site [active]
272843005121	metal binding site [ion binding]; metal-binding site
272843005122	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
272843005123	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843005124	Walker A/P-loop; other site
272843005125	ATP binding site [chemical binding]; other site
272843005126	Q-loop/lid; other site
272843005127	ABC transporter signature motif; other site
272843005128	Walker B; other site
272843005129	D-loop; other site
272843005130	H-loop/switch region; other site
272843005131	TOBE domain; Region: TOBE_2; pfam08402
272843005132	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
272843005133	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843005134	dimer interface [polypeptide binding]; other site
272843005135	conserved gate region; other site
272843005136	putative PBP binding loops; other site
272843005137	ABC-ATPase subunit interface; other site
272843005138	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843005139	dimer interface [polypeptide binding]; other site
272843005140	conserved gate region; other site
272843005141	putative PBP binding loops; other site
272843005142	ABC-ATPase subunit interface; other site
272843005143	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
272843005144	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843005145	Walker A/P-loop; other site
272843005146	ATP binding site [chemical binding]; other site
272843005147	Q-loop/lid; other site
272843005148	ABC transporter signature motif; other site
272843005149	Walker B; other site
272843005150	D-loop; other site
272843005151	H-loop/switch region; other site
272843005152	TOBE domain; Region: TOBE_2; pfam08402
272843005153	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
272843005154	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
272843005155	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
272843005156	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
272843005157	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
272843005158	HAMP domain; Region: HAMP; pfam00672
272843005159	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
272843005160	dimer interface [polypeptide binding]; other site
272843005161	phosphorylation site [posttranslational modification]
272843005162	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843005163	ATP binding site [chemical binding]; other site
272843005164	Mg2+ binding site [ion binding]; other site
272843005165	G-X-G motif; other site
272843005166	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
272843005167	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843005168	active site
272843005169	phosphorylation site [posttranslational modification]
272843005170	intermolecular recognition site; other site
272843005171	dimerization interface [polypeptide binding]; other site
272843005172	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
272843005173	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
272843005174	Predicted membrane protein [Function unknown]; Region: COG2855
272843005175	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
272843005176	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
272843005177	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
272843005178	Glutamine amidotransferase class-I; Region: GATase; pfam00117
272843005179	glutamine binding [chemical binding]; other site
272843005180	catalytic triad [active]
272843005181	para-aminobenzoate synthase component I; Validated; Region: PRK07093
272843005182	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
272843005183	hypothetical protein; Provisional; Region: PRK07101
272843005184	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
272843005185	substrate-cofactor binding pocket; other site
272843005186	homodimer interface [polypeptide binding]; other site
272843005187	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843005188	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
272843005189	homotrimer interaction site [polypeptide binding]; other site
272843005190	putative active site [active]
272843005191	NIPSNAP; Region: NIPSNAP; pfam07978
272843005192	Site-specific recombinase [DNA replication, recombination, and repair]; Region: COG4389
272843005193	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
272843005194	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
272843005195	substrate binding site [chemical binding]; other site
272843005196	Predicted transcriptional regulators [Transcription]; Region: COG1733
272843005197	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
272843005198	Predicted flavoprotein [General function prediction only]; Region: COG0431
272843005199	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
272843005200	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
272843005201	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
272843005202	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843005203	Walker A/P-loop; other site
272843005204	ATP binding site [chemical binding]; other site
272843005205	Q-loop/lid; other site
272843005206	ABC transporter signature motif; other site
272843005207	Walker B; other site
272843005208	D-loop; other site
272843005209	H-loop/switch region; other site
272843005210	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
272843005211	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
272843005212	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843005213	Walker A/P-loop; other site
272843005214	ATP binding site [chemical binding]; other site
272843005215	Q-loop/lid; other site
272843005216	ABC transporter signature motif; other site
272843005217	Walker B; other site
272843005218	D-loop; other site
272843005219	H-loop/switch region; other site
272843005220	EamA-like transporter family; Region: EamA; pfam00892
272843005221	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
272843005222	EamA-like transporter family; Region: EamA; pfam00892
272843005223	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
272843005224	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843005225	ATP binding site [chemical binding]; other site
272843005226	Mg2+ binding site [ion binding]; other site
272843005227	G-X-G motif; other site
272843005228	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
272843005229	anchoring element; other site
272843005230	dimer interface [polypeptide binding]; other site
272843005231	ATP binding site [chemical binding]; other site
272843005232	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
272843005233	active site
272843005234	putative metal-binding site [ion binding]; other site
272843005235	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
272843005236	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
272843005237	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
272843005238	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
272843005239	active site residue [active]
272843005240	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
272843005241	dimerization interface [polypeptide binding]; other site
272843005242	putative DNA binding site [nucleotide binding]; other site
272843005243	putative Zn2+ binding site [ion binding]; other site
272843005244	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
272843005245	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
272843005246	putative active site [active]
272843005247	Protein of unknown function (DUF904); Region: DUF904; pfam06005
272843005248	FMN-binding protein MioC; Provisional; Region: PRK09004
272843005249	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
272843005250	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
272843005251	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
272843005252	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
272843005253	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
272843005254	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
272843005255	F0F1 ATP synthase subunit I; Validated; Region: PRK06099
272843005256	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
272843005257	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
272843005258	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
272843005259	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
272843005260	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
272843005261	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
272843005262	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
272843005263	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
272843005264	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
272843005265	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
272843005266	beta subunit interaction interface [polypeptide binding]; other site
272843005267	Walker A motif; other site
272843005268	ATP binding site [chemical binding]; other site
272843005269	Walker B motif; other site
272843005270	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
272843005271	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
272843005272	core domain interface [polypeptide binding]; other site
272843005273	delta subunit interface [polypeptide binding]; other site
272843005274	epsilon subunit interface [polypeptide binding]; other site
272843005275	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
272843005276	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
272843005277	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
272843005278	alpha subunit interaction interface [polypeptide binding]; other site
272843005279	Walker A motif; other site
272843005280	ATP binding site [chemical binding]; other site
272843005281	Walker B motif; other site
272843005282	inhibitor binding site; inhibition site
272843005283	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
272843005284	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
272843005285	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
272843005286	gamma subunit interface [polypeptide binding]; other site
272843005287	epsilon subunit interface [polypeptide binding]; other site
272843005288	LBP interface [polypeptide binding]; other site
272843005289	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
272843005290	CPxP  motif; other site
272843005291	hypothetical protein; Provisional; Region: PRK11568
272843005292	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
272843005293	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
272843005294	Cation transport protein; Region: TrkH; cl17365
272843005295	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
272843005296	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
272843005297	hypothetical protein; Validated; Region: PRK05445
272843005298	Surface lipoprotein [Cell envelope biogenesis, outer membrane]; Region: VacJ; COG2853
272843005299	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
272843005300	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
272843005301	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
272843005302	catalytic site [active]
272843005303	subunit interface [polypeptide binding]; other site
272843005304	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
272843005305	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
272843005306	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
272843005307	conserved cys residue [active]
272843005308	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
272843005309	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
272843005310	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
272843005311	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
272843005312	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
272843005313	ATP-grasp domain; Region: ATP-grasp_4; cl17255
272843005314	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
272843005315	IMP binding site; other site
272843005316	dimer interface [polypeptide binding]; other site
272843005317	interdomain contacts; other site
272843005318	partial ornithine binding site; other site
272843005319	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
272843005320	catalytic core [active]
272843005321	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
272843005322	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
272843005323	Peptidase family M23; Region: Peptidase_M23; pfam01551
272843005324	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
272843005325	NodB motif; other site
272843005326	putative active site [active]
272843005327	putative catalytic site [active]
272843005328	Zn binding site [ion binding]; other site
272843005329	Mg chelatase-related protein; Region: TIGR00368
272843005330	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
272843005331	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843005332	Walker A motif; other site
272843005333	ATP binding site [chemical binding]; other site
272843005334	Walker B motif; other site
272843005335	arginine finger; other site
272843005336	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
272843005337	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
272843005338	G1 box; other site
272843005339	GTP/Mg2+ binding site [chemical binding]; other site
272843005340	Switch I region; other site
272843005341	G2 box; other site
272843005342	G3 box; other site
272843005343	Switch II region; other site
272843005344	G4 box; other site
272843005345	G5 box; other site
272843005346	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
272843005347	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
272843005348	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
272843005349	binding surface
272843005350	Tetratricopeptide repeat; Region: TPR_16; pfam13432
272843005351	TPR motif; other site
272843005352	Protein of unknown function (DUF560); Region: DUF560; pfam04575
272843005353	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
272843005354	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843005355	S-adenosylmethionine binding site [chemical binding]; other site
272843005356	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
272843005357	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
272843005358	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
272843005359	P loop; other site
272843005360	GTP binding site [chemical binding]; other site
272843005361	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
272843005362	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843005363	Walker A/P-loop; other site
272843005364	ATP binding site [chemical binding]; other site
272843005365	Q-loop/lid; other site
272843005366	ABC transporter signature motif; other site
272843005367	Walker B; other site
272843005368	D-loop; other site
272843005369	H-loop/switch region; other site
272843005370	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
272843005371	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
272843005372	4-hydroxyphenylacetate 3-monooxygenase, reductase component; Region: HpaC; TIGR02296
272843005373	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
272843005374	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
272843005375	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
272843005376	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
272843005377	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
272843005378	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
272843005379	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
272843005380	Tripartite ATP-independent periplasmic transporters, DctQ component; Region: DctQ; pfam04290
272843005381	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
272843005382	DctM-like transporters; Region: DctM; pfam06808
272843005383	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
272843005384	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit; Region: HpaG-N-term; TIGR02305
272843005385	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
272843005386	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
272843005387	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
272843005388	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
272843005389	NAD binding site [chemical binding]; other site
272843005390	catalytic residues [active]
272843005391	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
272843005392	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
272843005393	putative active site [active]
272843005394	putative metal binding site [ion binding]; other site
272843005395	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
272843005396	putative substrate binding pocket [chemical binding]; other site
272843005397	trimer interface [polypeptide binding]; other site
272843005398	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
272843005399	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843005400	putative substrate translocation pore; other site
272843005401	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
272843005402	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Region: HpaI; TIGR02311
272843005403	succinic semialdehyde dehydrogenase; Region: PLN02278
272843005404	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
272843005405	tetramerization interface [polypeptide binding]; other site
272843005406	NAD(P) binding site [chemical binding]; other site
272843005407	catalytic residues [active]
272843005408	HsdM N-terminal domain; Region: HsdM_N; pfam12161
272843005409	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
272843005410	Methyltransferase domain; Region: Methyltransf_26; pfam13659
272843005411	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
272843005412	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
272843005413	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
272843005414	Abortive infection bacteriophage resistance protein [Defense mechanisms]; Region: AbiF; COG4823
272843005415	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
272843005416	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
272843005417	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843005418	ATP binding site [chemical binding]; other site
272843005419	putative Mg++ binding site [ion binding]; other site
272843005420	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
272843005421	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
272843005422	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
272843005423	active site
272843005424	substrate-binding site [chemical binding]; other site
272843005425	metal-binding site [ion binding]
272843005426	ATP binding site [chemical binding]; other site
272843005427	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
272843005428	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
272843005429	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
272843005430	ADP-ribose binding site [chemical binding]; other site
272843005431	dimer interface [polypeptide binding]; other site
272843005432	active site
272843005433	nudix motif; other site
272843005434	metal binding site [ion binding]; metal-binding site
272843005435	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
272843005436	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
272843005437	motif II; other site
272843005438	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
272843005439	RNA binding surface [nucleotide binding]; other site
272843005440	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
272843005441	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
272843005442	dimerization interface [polypeptide binding]; other site
272843005443	domain crossover interface; other site
272843005444	redox-dependent activation switch; other site
272843005445	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
272843005446	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
272843005447	active site
272843005448	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
272843005449	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
272843005450	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
272843005451	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
272843005452	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
272843005453	putative active site [active]
272843005454	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
272843005455	GST_N family, unknown subfamily 1; composed of uncharacterized proteins, predominantly from bacteria, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; Region: GST_N_1; cd03043
272843005456	putative C-terminal domain interface [polypeptide binding]; other site
272843005457	putative GSH binding site (G-site) [chemical binding]; other site
272843005458	putative dimer interface [polypeptide binding]; other site
272843005459	C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases; Region: GST_C_3; cd03194
272843005460	putative N-terminal domain interface [polypeptide binding]; other site
272843005461	putative dimer interface [polypeptide binding]; other site
272843005462	putative substrate binding pocket (H-site) [chemical binding]; other site
272843005463	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
272843005464	Coenzyme A binding pocket [chemical binding]; other site
272843005465	6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG0362
272843005466	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
272843005467	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
272843005468	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
272843005469	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843005470	active site
272843005471	motif I; other site
272843005472	motif II; other site
272843005473	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843005474	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
272843005475	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843005476	active site
272843005477	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
272843005478	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
272843005479	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
272843005480	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
272843005481	TfoX C-terminal domain; Region: TfoX_C; pfam04994
272843005482	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
272843005483	active site
272843005484	catalytic residues [active]
272843005485	metal binding site [ion binding]; metal-binding site
272843005486	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
272843005487	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
272843005488	putative active site [active]
272843005489	substrate binding site [chemical binding]; other site
272843005490	putative cosubstrate binding site; other site
272843005491	catalytic site [active]
272843005492	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
272843005493	substrate binding site [chemical binding]; other site
272843005494	16S rRNA methyltransferase B; Provisional; Region: PRK10901
272843005495	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
272843005496	putative RNA binding site [nucleotide binding]; other site
272843005497	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843005498	S-adenosylmethionine binding site [chemical binding]; other site
272843005499	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
272843005500	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
272843005501	active site
272843005502	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
272843005503	TrkA-N domain; Region: TrkA_N; pfam02254
272843005504	TrkA-C domain; Region: TrkA_C; pfam02080
272843005505	TrkA-N domain; Region: TrkA_N; pfam02254
272843005506	TrkA-C domain; Region: TrkA_C; pfam02080
272843005507	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
272843005508	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
272843005509	RNase E inhibitor protein; Provisional; Region: PRK11191
272843005510	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
272843005511	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3471
272843005512	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
272843005513	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
272843005514	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
272843005515	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
272843005516	Low molecular weight phosphatase family; Region: LMWPc; cd00115
272843005517	active site
272843005518	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
272843005519	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
272843005520	trimer interface [polypeptide binding]; other site
272843005521	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
272843005522	trimer interface [polypeptide binding]; other site
272843005523	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
272843005524	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
272843005525	trimer interface [polypeptide binding]; other site
272843005526	YadA-like C-terminal region; Region: YadA; pfam03895
272843005527	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
272843005528	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
272843005529	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843005530	FeS/SAM binding site; other site
272843005531	TRAM domain; Region: TRAM; cl01282
272843005532	uridine phosphorylase; Provisional; Region: PRK11178
272843005533	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
272843005534	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
272843005535	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
272843005536	putative DNA binding site [nucleotide binding]; other site
272843005537	putative Zn2+ binding site [ion binding]; other site
272843005538	AsnC family; Region: AsnC_trans_reg; pfam01037
272843005539	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
272843005540	dimer interface [polypeptide binding]; other site
272843005541	active site
272843005542	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
272843005543	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
272843005544	active site turn [active]
272843005545	phosphorylation site [posttranslational modification]
272843005546	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
272843005547	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
272843005548	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
272843005549	putative active site [active]
272843005550	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
272843005551	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
272843005552	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
272843005553	putative active site [active]
272843005554	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
272843005555	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
272843005556	substrate binding pocket [chemical binding]; other site
272843005557	membrane-bound complex binding site; other site
272843005558	Uncharacterized conserved protein [Function unknown]; Region: COG4729
272843005559	TRAP transporter, 4TM/12TM fusion protein; Region: TRAP_fused; TIGR02123
272843005560	DctM-like transporters; Region: DctM; pfam06808
272843005561	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
272843005562	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
272843005563	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843005564	Walker A/P-loop; other site
272843005565	ATP binding site [chemical binding]; other site
272843005566	Q-loop/lid; other site
272843005567	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
272843005568	ABC transporter; Region: ABC_tran_2; pfam12848
272843005569	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
272843005570	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
272843005571	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
272843005572	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
272843005573	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
272843005574	DNA binding residues [nucleotide binding]
272843005575	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
272843005576	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
272843005577	transmembrane helices; other site
272843005578	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
272843005579	PLD-like domain; Region: PLDc_2; pfam13091
272843005580	putative active site [active]
272843005581	catalytic site [active]
272843005582	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
272843005583	PLD-like domain; Region: PLDc_2; pfam13091
272843005584	putative active site [active]
272843005585	catalytic site [active]
272843005586	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
272843005587	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
272843005588	gating phenylalanine in ion channel; other site
272843005589	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4390
272843005590	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
272843005591	FAD binding domain; Region: FAD_binding_4; pfam01565
272843005592	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
272843005593	Peptidase E [Amino acid transport and metabolism]; Region: PepE; COG3340
272843005594	conserved cys residue [active]
272843005595	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
272843005596	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
272843005597	HAMP domain; Region: HAMP; pfam00672
272843005598	Histidine kinase; Region: HisKA_3; pfam07730
272843005599	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843005600	ATP binding site [chemical binding]; other site
272843005601	Mg2+ binding site [ion binding]; other site
272843005602	G-X-G motif; other site
272843005603	ferredoxin-type protein NapF; Region: napF; TIGR00402
272843005604	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
272843005605	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
272843005606	Uncharacterized protein involved in formation of periplasmic nitrate reductase [Inorganic ion transport and metabolism]; Region: NapD; COG3062
272843005607	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
272843005608	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
272843005609	[4Fe-4S] binding site [ion binding]; other site
272843005610	molybdopterin cofactor binding site; other site
272843005611	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
272843005612	molybdopterin cofactor binding site; other site
272843005613	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
272843005614	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
272843005615	4Fe-4S binding domain; Region: Fer4_5; pfam12801
272843005616	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
272843005617	Nitrate reductase cytochrome c-type subunit [Energy production and conversion]; Region: NapB; COG3043
272843005618	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
272843005619	periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; Region: napC_nirT; TIGR02161
272843005620	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
272843005621	DNA protecting protein DprA; Region: dprA; TIGR00732
272843005622	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
272843005623	OstA-like protein; Region: OstA; pfam03968
272843005624	Organic solvent tolerance protein; Region: OstA_C; pfam04453
272843005625	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
272843005626	transaldolase-like protein; Provisional; Region: PTZ00411
272843005627	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
272843005628	active site
272843005629	dimer interface [polypeptide binding]; other site
272843005630	catalytic residue [active]
272843005631	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
272843005632	nudix motif; other site
272843005633	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
272843005634	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
272843005635	active site
272843005636	isocitrate dehydrogenase; Validated; Region: PRK07362
272843005637	isocitrate dehydrogenase; Reviewed; Region: PRK07006
272843005638	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
272843005639	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
272843005640	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
272843005641	substrate binding site; other site
272843005642	dimer interface; other site
272843005643	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
272843005644	homotrimer interaction site [polypeptide binding]; other site
272843005645	zinc binding site [ion binding]; other site
272843005646	CDP-binding sites; other site
272843005647	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
272843005648	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
272843005649	Permutation of conserved domain; other site
272843005650	active site
272843005651	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
272843005652	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
272843005653	Sel1-like repeats; Region: SEL1; smart00671
272843005654	Sel1-like repeats; Region: SEL1; smart00671
272843005655	Sel1-like repeats; Region: SEL1; smart00671
272843005656	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
272843005657	Predicted membrane protein [Function unknown]; Region: COG1238
272843005658	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
272843005659	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
272843005660	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
272843005661	Peptidase family M23; Region: Peptidase_M23; pfam01551
272843005662	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
272843005663	putative active site [active]
272843005664	dimerization interface [polypeptide binding]; other site
272843005665	putative tRNAtyr binding site [nucleotide binding]; other site
272843005666	hypothetical protein; Reviewed; Region: PRK01637
272843005667	hypothetical protein; Provisional; Region: PRK01752
272843005668	SEC-C motif; Region: SEC-C; pfam02810
272843005669	Lysine efflux permease [General function prediction only]; Region: COG1279
272843005670	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
272843005671	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
272843005672	substrate binding site [chemical binding]; other site
272843005673	hexamer interface [polypeptide binding]; other site
272843005674	metal binding site [ion binding]; metal-binding site
272843005675	phosphoglycolate phosphatase; Provisional; Region: PRK13222
272843005676	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
272843005677	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843005678	motif II; other site
272843005679	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
272843005680	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
272843005681	active site
272843005682	HIGH motif; other site
272843005683	dimer interface [polypeptide binding]; other site
272843005684	KMSKS motif; other site
272843005685	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
272843005686	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
272843005687	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
272843005688	threonine dehydratase; Reviewed; Region: PRK09224
272843005689	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
272843005690	tetramer interface [polypeptide binding]; other site
272843005691	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843005692	catalytic residue [active]
272843005693	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
272843005694	putative Ile/Val binding site [chemical binding]; other site
272843005695	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
272843005696	putative Ile/Val binding site [chemical binding]; other site
272843005697	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
272843005698	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
272843005699	aspartate racemase; Region: asp_race; TIGR00035
272843005700	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
272843005701	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
272843005702	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
272843005703	PYR/PP interface [polypeptide binding]; other site
272843005704	dimer interface [polypeptide binding]; other site
272843005705	TPP binding site [chemical binding]; other site
272843005706	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
272843005707	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
272843005708	TPP-binding site [chemical binding]; other site
272843005709	dimer interface [polypeptide binding]; other site
272843005710	putative hydrolase; Provisional; Region: PRK10976
272843005711	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843005712	active site
272843005713	motif I; other site
272843005714	motif II; other site
272843005715	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
272843005716	chromosome condensation membrane protein; Provisional; Region: PRK14196
272843005717	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
272843005718	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
272843005719	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
272843005720	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
272843005721	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3792
272843005722	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3792
272843005723	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3792
272843005724	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3792
272843005725	transketolase; Reviewed; Region: PRK12753
272843005726	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
272843005727	TPP-binding site [chemical binding]; other site
272843005728	dimer interface [polypeptide binding]; other site
272843005729	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
272843005730	PYR/PP interface [polypeptide binding]; other site
272843005731	dimer interface [polypeptide binding]; other site
272843005732	TPP binding site [chemical binding]; other site
272843005733	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
272843005734	transaldolase-like protein; Provisional; Region: PTZ00411
272843005735	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
272843005736	active site
272843005737	dimer interface [polypeptide binding]; other site
272843005738	catalytic residue [active]
272843005739	triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional; Region: PRK14905
272843005740	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
272843005741	substrate binding site [chemical binding]; other site
272843005742	dimer interface [polypeptide binding]; other site
272843005743	catalytic triad [active]
272843005744	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
272843005745	active site turn [active]
272843005746	phosphorylation site [posttranslational modification]
272843005747	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
272843005748	DctM-like transporters; Region: DctM; pfam06808
272843005749	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
272843005750	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
272843005751	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
272843005752	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
272843005753	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
272843005754	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
272843005755	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
272843005756	DNA binding residues [nucleotide binding]
272843005757	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
272843005758	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
272843005759	DAK2 domain; Region: Dak2; pfam02734
272843005760	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
272843005761	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
272843005762	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
272843005763	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
272843005764	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
272843005765	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
272843005766	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
272843005767	DctM-like transporters; Region: DctM; pfam06808
272843005768	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
272843005769	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
272843005770	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
272843005771	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
272843005772	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843005773	motif II; other site
272843005774	Uncharacterized membrane protein affecting hemolysin expression [General function prediction only]; Region: AhpA; COG3726
272843005775	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
272843005776	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
272843005777	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
272843005778	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
272843005779	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
272843005780	active site
272843005781	Riboflavin kinase; Region: Flavokinase; smart00904
272843005782	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
272843005783	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
272843005784	active site
272843005785	HIGH motif; other site
272843005786	nucleotide binding site [chemical binding]; other site
272843005787	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
272843005788	active site
272843005789	KMSKS motif; other site
272843005790	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
272843005791	tRNA binding surface [nucleotide binding]; other site
272843005792	anticodon binding site; other site
272843005793	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
272843005794	lipoprotein signal peptidase; Provisional; Region: PRK14787
272843005795	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
272843005796	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
272843005797	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
272843005798	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
272843005799	active site
272843005800	dimerization interface [polypeptide binding]; other site
272843005801	Uncharacterized conserved protein [Function unknown]; Region: COG0393
272843005802	HemN family oxidoreductase; Provisional; Region: PRK05660
272843005803	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843005804	FeS/SAM binding site; other site
272843005805	HemN C-terminal domain; Region: HemN_C; pfam06969
272843005806	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
272843005807	tetramer (dimer of dimers) interface [polypeptide binding]; other site
272843005808	active site
272843005809	dimer interface [polypeptide binding]; other site
272843005810	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
272843005811	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
272843005812	ligand binding site [chemical binding]; other site
272843005813	NAD binding site [chemical binding]; other site
272843005814	tetramer interface [polypeptide binding]; other site
272843005815	catalytic site [active]
272843005816	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
272843005817	L-serine binding site [chemical binding]; other site
272843005818	ACT domain interface; other site
272843005819	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
272843005820	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
272843005821	dimerization interface [polypeptide binding]; other site
272843005822	thymidylate kinase; Validated; Region: tmk; PRK00698
272843005823	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
272843005824	TMP-binding site; other site
272843005825	ATP-binding site [chemical binding]; other site
272843005826	DNA polymerase III subunit delta'; Validated; Region: PRK06871
272843005827	DNA polymerase III subunit delta'; Validated; Region: PRK08485
272843005828	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
272843005829	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
272843005830	active site
272843005831	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
272843005832	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
272843005833	Domain of unknown function DUF21; Region: DUF21; pfam01595
272843005834	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
272843005835	Transporter associated domain; Region: CorC_HlyC; smart01091
272843005836	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
272843005837	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843005838	FeS/SAM binding site; other site
272843005839	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
272843005840	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
272843005841	membrane-bound complex binding site; other site
272843005842	hinge residues; other site
272843005843	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
272843005844	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
272843005845	Sulfatase; Region: Sulfatase; cl17466
272843005846	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
272843005847	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
272843005848	Sulfatase; Region: Sulfatase; pfam00884
272843005849	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09560
272843005850	Pirin-related protein [General function prediction only]; Region: COG1741
272843005851	Pirin; Region: Pirin; pfam02678
272843005852	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
272843005853	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843005854	S-adenosylmethionine binding site [chemical binding]; other site
272843005855	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
272843005856	SCP-2 sterol transfer family; Region: SCP2; pfam02036
272843005857	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
272843005858	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
272843005859	twin arginine translocase protein A; Provisional; Region: tatA; PRK01833
272843005860	sec-independent translocase; Provisional; Region: PRK01770
272843005861	Sec-independent protein translocase protein (TatC); Region: TatC; cl00521
272843005862	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
272843005863	dimer interface [polypeptide binding]; other site
272843005864	allosteric magnesium binding site [ion binding]; other site
272843005865	active site
272843005866	aspartate-rich active site metal binding site; other site
272843005867	Schiff base residues; other site
272843005868	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
272843005869	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
272843005870	dimer interface [polypeptide binding]; other site
272843005871	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843005872	catalytic residue [active]
272843005873	putative sulfate transport protein CysZ; Validated; Region: PRK04949
272843005874	cell division protein ZipA; Provisional; Region: PRK01741
272843005875	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
272843005876	FtsZ protein binding site [polypeptide binding]; other site
272843005877	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
272843005878	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
272843005879	homooctamer interface [polypeptide binding]; other site
272843005880	active site
272843005881	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
272843005882	EamA-like transporter family; Region: EamA; pfam00892
272843005883	EamA-like transporter family; Region: EamA; pfam00892
272843005884	SnoaL-like domain; Region: SnoaL_2; pfam12680
272843005885	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
272843005886	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843005887	motif II; other site
272843005888	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
272843005889	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
272843005890	active site
272843005891	Int/Topo IB signature motif; other site
272843005892	hypothetical protein; Provisional; Region: PRK10963
272843005893	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
272843005894	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
272843005895	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
272843005896	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
272843005897	Clp amino terminal domain; Region: Clp_N; pfam02861
272843005898	Clp amino terminal domain; Region: Clp_N; pfam02861
272843005899	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843005900	Walker A motif; other site
272843005901	ATP binding site [chemical binding]; other site
272843005902	Walker B motif; other site
272843005903	arginine finger; other site
272843005904	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843005905	Walker A motif; other site
272843005906	ATP binding site [chemical binding]; other site
272843005907	Walker B motif; other site
272843005908	arginine finger; other site
272843005909	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
272843005910	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
272843005911	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
272843005912	catalytic residues [active]
272843005913	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
272843005914	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
272843005915	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
272843005916	Kelch motif; Region: Kelch_1; pfam01344
272843005917	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
272843005918	DctM-like transporters; Region: DctM; pfam06808
272843005919	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
272843005920	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
272843005921	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
272843005922	NnaC (CMP-NeuNAc synthetase) _like subfamily of SGNH_hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: NnaC_like; cd01841
272843005923	active site
272843005924	catalytic triad [active]
272843005925	oxyanion hole [active]
272843005926	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
272843005927	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
272843005928	putative active site cavity [active]
272843005929	N-acetylmannosamine kinase; Provisional; Region: PRK05082
272843005930	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
272843005931	nucleotide binding site [chemical binding]; other site
272843005932	Domain of unknown function (DUF386); Region: DUF386; pfam04074
272843005933	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
272843005934	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
272843005935	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
272843005936	putative active site [active]
272843005937	N-acetylneuraminate lyase; Provisional; Region: PRK04147
272843005938	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
272843005939	inhibitor site; inhibition site
272843005940	active site
272843005941	dimer interface [polypeptide binding]; other site
272843005942	catalytic residue [active]
272843005943	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
272843005944	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
272843005945	nucleotide binding pocket [chemical binding]; other site
272843005946	K-X-D-G motif; other site
272843005947	catalytic site [active]
272843005948	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
272843005949	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
272843005950	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
272843005951	Dimer interface [polypeptide binding]; other site
272843005952	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
272843005953	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
272843005954	Autotransporter beta-domain; Region: Autotransporter; pfam03797
272843005955	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
272843005956	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
272843005957	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
272843005958	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
272843005959	RNA binding surface [nucleotide binding]; other site
272843005960	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
272843005961	active site
272843005962	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
272843005963	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
272843005964	binding surface
272843005965	TPR motif; other site
272843005966	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
272843005967	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
272843005968	Cell division protein ZapA (stimulator of FtsZ polymerization and Z-ring component) [Cell cycle control, cell division,    chromosome partitioning]; Region: zapA; COG3027
272843005969	hypothetical protein; Reviewed; Region: PRK01736
272843005970	proline aminopeptidase P II; Provisional; Region: PRK10879
272843005971	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
272843005972	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
272843005973	active site
272843005974	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
272843005975	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
272843005976	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
272843005977	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
272843005978	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
272843005979	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843005980	active site
272843005981	motif I; other site
272843005982	motif II; other site
272843005983	D-methionine ABC transporter, ATP-binding protein; Region: ABC_MetN; TIGR02314
272843005984	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
272843005985	Walker A/P-loop; other site
272843005986	ATP binding site [chemical binding]; other site
272843005987	Q-loop/lid; other site
272843005988	ABC transporter signature motif; other site
272843005989	Walker B; other site
272843005990	D-loop; other site
272843005991	H-loop/switch region; other site
272843005992	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
272843005993	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843005994	dimer interface [polypeptide binding]; other site
272843005995	conserved gate region; other site
272843005996	ABC-ATPase subunit interface; other site
272843005997	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
272843005998	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
272843005999	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
272843006000	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
272843006001	glutaminase active site [active]
272843006002	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
272843006003	dimer interface [polypeptide binding]; other site
272843006004	active site
272843006005	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
272843006006	dimer interface [polypeptide binding]; other site
272843006007	active site
272843006008	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
272843006009	IHF dimer interface [polypeptide binding]; other site
272843006010	IHF - DNA interface [nucleotide binding]; other site
272843006011	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
272843006012	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
272843006013	substrate binding site [chemical binding]; other site
272843006014	active site
272843006015	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
272843006016	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
272843006017	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
272843006018	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
272843006019	putative NADH binding site [chemical binding]; other site
272843006020	putative active site [active]
272843006021	nudix motif; other site
272843006022	putative metal binding site [ion binding]; other site
272843006023	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
272843006024	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
272843006025	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
272843006026	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
272843006027	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
272843006028	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
272843006029	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
272843006030	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
272843006031	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
272843006032	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
272843006033	DNA binding site [nucleotide binding]
272843006034	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
272843006035	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
272843006036	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
272843006037	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
272843006038	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
272843006039	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
272843006040	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
272843006041	RPB1 interaction site [polypeptide binding]; other site
272843006042	RPB11 interaction site [polypeptide binding]; other site
272843006043	RPB10 interaction site [polypeptide binding]; other site
272843006044	RPB3 interaction site [polypeptide binding]; other site
272843006045	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
272843006046	core dimer interface [polypeptide binding]; other site
272843006047	peripheral dimer interface [polypeptide binding]; other site
272843006048	L10 interface [polypeptide binding]; other site
272843006049	L11 interface [polypeptide binding]; other site
272843006050	putative EF-Tu interaction site [polypeptide binding]; other site
272843006051	putative EF-G interaction site [polypeptide binding]; other site
272843006052	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
272843006053	23S rRNA interface [nucleotide binding]; other site
272843006054	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
272843006055	fructuronate transporter; Provisional; Region: PRK10034; cl15264
272843006056	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
272843006057	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
272843006058	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
272843006059	mRNA/rRNA interface [nucleotide binding]; other site
272843006060	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
272843006061	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
272843006062	23S rRNA interface [nucleotide binding]; other site
272843006063	L7/L12 interface [polypeptide binding]; other site
272843006064	putative thiostrepton binding site; other site
272843006065	L25 interface [polypeptide binding]; other site
272843006066	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
272843006067	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
272843006068	putative homodimer interface [polypeptide binding]; other site
272843006069	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
272843006070	heterodimer interface [polypeptide binding]; other site
272843006071	homodimer interface [polypeptide binding]; other site
272843006072	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
272843006073	elongation factor Tu; Reviewed; Region: PRK00049
272843006074	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
272843006075	G1 box; other site
272843006076	GEF interaction site [polypeptide binding]; other site
272843006077	GTP/Mg2+ binding site [chemical binding]; other site
272843006078	Switch I region; other site
272843006079	G2 box; other site
272843006080	G3 box; other site
272843006081	Switch II region; other site
272843006082	G4 box; other site
272843006083	G5 box; other site
272843006084	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
272843006085	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
272843006086	Antibiotic Binding Site [chemical binding]; other site
272843006087	pantothenate kinase; Provisional; Region: PRK05439
272843006088	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
272843006089	ATP-binding site [chemical binding]; other site
272843006090	CoA-binding site [chemical binding]; other site
272843006091	Mg2+-binding site [ion binding]; other site
272843006092	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
272843006093	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843006094	Walker A motif; other site
272843006095	ATP binding site [chemical binding]; other site
272843006096	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
272843006097	Walker B motif; other site
272843006098	arginine finger; other site
272843006099	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
272843006100	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
272843006101	HslU subunit interaction site [polypeptide binding]; other site
272843006102	DNA alkylation repair enzyme [DNA replication, recombination, and repair]; Region: COG4335
272843006103	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
272843006104	UbiA prenyltransferase family; Region: UbiA; pfam01040
272843006105	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
272843006106	PTS system, glucose-like IIB component; Region: EIIB_glc; TIGR00826
272843006107	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
272843006108	active site turn [active]
272843006109	phosphorylation site [posttranslational modification]
272843006110	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
272843006111	MgtC family; Region: MgtC; pfam02308
272843006112	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
272843006113	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
272843006114	putative [Fe4-S4] binding site [ion binding]; other site
272843006115	putative molybdopterin cofactor binding site [chemical binding]; other site
272843006116	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
272843006117	putative molybdopterin cofactor binding site; other site
272843006118	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
272843006119	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
272843006120	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
272843006121	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
272843006122	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
272843006123	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
272843006124	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
272843006125	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
272843006126	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
272843006127	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843006128	dimer interface [polypeptide binding]; other site
272843006129	conserved gate region; other site
272843006130	putative PBP binding loops; other site
272843006131	ABC-ATPase subunit interface; other site
272843006132	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
272843006133	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843006134	dimer interface [polypeptide binding]; other site
272843006135	conserved gate region; other site
272843006136	putative PBP binding loops; other site
272843006137	ABC-ATPase subunit interface; other site
272843006138	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
272843006139	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
272843006140	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
272843006141	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
272843006142	Walker A/P-loop; other site
272843006143	ATP binding site [chemical binding]; other site
272843006144	Q-loop/lid; other site
272843006145	ABC transporter signature motif; other site
272843006146	Walker B; other site
272843006147	D-loop; other site
272843006148	H-loop/switch region; other site
272843006149	TOBE domain; Region: TOBE_2; pfam08402
272843006150	Transcriptional regulators [Transcription]; Region: FadR; COG2186
272843006151	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
272843006152	DNA-binding site [nucleotide binding]; DNA binding site
272843006153	FCD domain; Region: FCD; pfam07729
272843006154	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
272843006155	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
272843006156	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
272843006157	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
272843006158	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
272843006159	G1 box; other site
272843006160	putative GEF interaction site [polypeptide binding]; other site
272843006161	GTP/Mg2+ binding site [chemical binding]; other site
272843006162	Switch I region; other site
272843006163	G2 box; other site
272843006164	G3 box; other site
272843006165	Switch II region; other site
272843006166	G4 box; other site
272843006167	G5 box; other site
272843006168	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
272843006169	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
272843006170	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
272843006171	DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is...; Region: DEP; cl02442
272843006172	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
272843006173	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
272843006174	active site
272843006175	tetramer interface [polypeptide binding]; other site
272843006176	selenocysteine synthase; Provisional; Region: PRK04311
272843006177	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
272843006178	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
272843006179	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
272843006180	catalytic residue [active]
272843006181	integrase; Provisional; Region: PRK09692
272843006182	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
272843006183	active site
272843006184	Int/Topo IB signature motif; other site
272843006185	Fic family protein [Function unknown]; Region: COG3177
272843006186	Fic/DOC family; Region: Fic; pfam02661
272843006187	phage regulatory protein, rha family; Region: phage_pRha; TIGR02681
272843006188	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3646
272843006189	Terminase small subunit; Region: Terminase_2; pfam03592
272843006190	Ash protein family; Region: Phage_ASH; pfam10554
272843006191	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
272843006192	Abortive infection bacteriophage resistance protein [Defense mechanisms]; Region: AbiF; COG4823
272843006193	putative transporter; Provisional; Region: PRK10504
272843006194	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843006195	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
272843006196	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
272843006197	Walker A motif; other site
272843006198	Positive regulator of sigma E activity [Signal transduction mechanisms]; Region: RseC; COG3086
272843006199	anti-sigma E factor; Provisional; Region: rseB; PRK09455
272843006200	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
272843006201	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseA; COG3073
272843006202	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
272843006203	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
272843006204	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
272843006205	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
272843006206	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
272843006207	DNA binding residues [nucleotide binding]
272843006208	Uncharacterized conserved protein [Function unknown]; Region: COG2938
272843006209	Choline-glycine betaine transporter [Cell envelope biogenesis, outer membrane]; Region: BetT; COG1292
272843006210	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
272843006211	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
272843006212	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
272843006213	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
272843006214	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
272843006215	molybdopterin cofactor binding site [chemical binding]; other site
272843006216	substrate binding site [chemical binding]; other site
272843006217	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
272843006218	molybdopterin cofactor binding site; other site
272843006219	chaperone protein TorD; Validated; Region: torD; PRK04976
272843006220	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
272843006221	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
272843006222	active site
272843006223	P-loop; other site
272843006224	phosphorylation site [posttranslational modification]
272843006225	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
272843006226	active site
272843006227	P-loop; other site
272843006228	phosphorylation site [posttranslational modification]
272843006229	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
272843006230	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
272843006231	putative substrate binding site [chemical binding]; other site
272843006232	putative ATP binding site [chemical binding]; other site
272843006233	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
272843006234	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
272843006235	active site
272843006236	phosphorylation site [posttranslational modification]
272843006237	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
272843006238	dimerization domain swap beta strand [polypeptide binding]; other site
272843006239	regulatory protein interface [polypeptide binding]; other site
272843006240	active site
272843006241	regulatory phosphorylation site [posttranslational modification]; other site
272843006242	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
272843006243	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
272843006244	GTP binding site; other site
272843006245	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3084
272843006246	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
272843006247	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
272843006248	catalytic residues [active]
272843006249	hinge region; other site
272843006250	alpha helical domain; other site
272843006251	hypothetical protein; Provisional; Region: PRK11027
272843006252	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
272843006253	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843006254	S-adenosylmethionine binding site [chemical binding]; other site
272843006255	Putative SAM-dependent methyltransferase; Region: SAM_MT; pfam04445
272843006256	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
272843006257	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
272843006258	Substrate binding site; other site
272843006259	Mg++ binding site; other site
272843006260	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
272843006261	active site
272843006262	substrate binding site [chemical binding]; other site
272843006263	CoA binding site [chemical binding]; other site
272843006264	exopolyphosphatase; Provisional; Region: PRK10854
272843006265	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
272843006266	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
272843006267	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
272843006268	Family of unknown function (DUF490); Region: DUF490; pfam04357
272843006269	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
272843006270	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
272843006271	Surface antigen; Region: Bac_surface_Ag; pfam01103
272843006272	transcriptional regulator NarP; Provisional; Region: PRK10403
272843006273	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843006274	active site
272843006275	phosphorylation site [posttranslational modification]
272843006276	intermolecular recognition site; other site
272843006277	dimerization interface [polypeptide binding]; other site
272843006278	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
272843006279	DNA binding residues [nucleotide binding]
272843006280	dimerization interface [polypeptide binding]; other site
272843006281	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
272843006282	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
272843006283	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
272843006284	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
272843006285	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
272843006286	domain interfaces; other site
272843006287	active site
272843006288	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
272843006289	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
272843006290	active site
272843006291	HemX; Region: HemX; pfam04375
272843006292	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
272843006293	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemY; COG3071
272843006294	HemY protein N-terminus; Region: HemY_N; pfam07219
272843006295	recombination regulator RecX; Reviewed; Region: recX; PRK00117
272843006296	recombinase A; Provisional; Region: recA; PRK09354
272843006297	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
272843006298	hexamer interface [polypeptide binding]; other site
272843006299	Walker A motif; other site
272843006300	ATP binding site [chemical binding]; other site
272843006301	Walker B motif; other site
272843006302	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
272843006303	Putative bacterial virulence factor; Region: Virul_Fac; pfam10139
272843006304	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
272843006305	metal ion-dependent adhesion site (MIDAS); other site
272843006306	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
272843006307	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
272843006308	Walker A/P-loop; other site
272843006309	ATP binding site [chemical binding]; other site
272843006310	Q-loop/lid; other site
272843006311	ABC transporter signature motif; other site
272843006312	Walker B; other site
272843006313	D-loop; other site
272843006314	H-loop/switch region; other site
272843006315	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
272843006316	FtsX-like permease family; Region: FtsX; pfam02687
272843006317	Uncharacterized conserved protein [Function unknown]; Region: COG1262
272843006318	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
272843006319	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
272843006320	VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_ywmD_type; cd01456
272843006321	metal ion-dependent adhesion site (MIDAS); other site
272843006322	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
272843006323	metal ion-dependent adhesion site (MIDAS); other site
272843006324	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
272843006325	MutS domain I; Region: MutS_I; pfam01624
272843006326	MutS domain II; Region: MutS_II; pfam05188
272843006327	MutS domain III; Region: MutS_III; pfam05192
272843006328	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
272843006329	Walker A/P-loop; other site
272843006330	ATP binding site [chemical binding]; other site
272843006331	Q-loop/lid; other site
272843006332	ABC transporter signature motif; other site
272843006333	Walker B; other site
272843006334	D-loop; other site
272843006335	H-loop/switch region; other site
272843006336	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
272843006337	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
272843006338	dimer interface [polypeptide binding]; other site
272843006339	FMN binding site [chemical binding]; other site
272843006340	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
272843006341	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843006342	FeS/SAM binding site; other site
272843006343	HemN C-terminal domain; Region: HemN_C; pfam06969
272843006344	Protein of unknown function (DUF2489); Region: DUF2489; pfam10675
272843006345	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
272843006346	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
272843006347	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
272843006348	active site
272843006349	ATP-dependent helicase HepA; Validated; Region: PRK04914
272843006350	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
272843006351	ATP binding site [chemical binding]; other site
272843006352	putative Mg++ binding site [ion binding]; other site
272843006353	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843006354	nucleotide binding region [chemical binding]; other site
272843006355	ATP-binding site [chemical binding]; other site
272843006356	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
272843006357	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
272843006358	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843006359	S-adenosylmethionine binding site [chemical binding]; other site
272843006360	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
272843006361	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
272843006362	ATP binding site [chemical binding]; other site
272843006363	Mg++ binding site [ion binding]; other site
272843006364	motif III; other site
272843006365	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843006366	nucleotide binding region [chemical binding]; other site
272843006367	ATP-binding site [chemical binding]; other site
272843006368	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
272843006369	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
272843006370	putative active site [active]
272843006371	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
272843006372	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
272843006373	putative active site [active]
272843006374	Copper(I)-binding protein [Inorganic ion transport and    metabolism]; Region: COG2847
272843006375	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
272843006376	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
272843006377	active site turn [active]
272843006378	phosphorylation site [posttranslational modification]
272843006379	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
272843006380	D-fructose-responsive transcription factor; Region: fruct_sucro_rep; TIGR02417
272843006381	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
272843006382	DNA binding site [nucleotide binding]
272843006383	domain linker motif; other site
272843006384	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
272843006385	dimerization interface [polypeptide binding]; other site
272843006386	ligand binding site [chemical binding]; other site
272843006387	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
272843006388	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
272843006389	substrate binding [chemical binding]; other site
272843006390	active site
272843006391	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
272843006392	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
272843006393	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
272843006394	putative substrate binding site [chemical binding]; other site
272843006395	putative ATP binding site [chemical binding]; other site
272843006396	Uncharacterized protein involved in purine metabolism [General function prediction only]; Region: COG2915
272843006397	adenylosuccinate lyase; Provisional; Region: PRK09285
272843006398	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
272843006399	tetramer interface [polypeptide binding]; other site
272843006400	active site
272843006401	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
272843006402	L-lactate permease; Region: Lactate_perm; cl00701
272843006403	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
272843006404	Cysteine-rich domain; Region: CCG; pfam02754
272843006405	Cysteine-rich domain; Region: CCG; pfam02754
272843006406	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
272843006407	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
272843006408	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
272843006409	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
272843006410	Uncharacterized conserved protein [Function unknown]; Region: COG1556
272843006411	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
272843006412	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
272843006413	domain interface [polypeptide binding]; other site
272843006414	putative active site [active]
272843006415	catalytic site [active]
272843006416	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
272843006417	domain interface [polypeptide binding]; other site
272843006418	putative active site [active]
272843006419	catalytic site [active]
272843006420	putative methyltransferase; Provisional; Region: PRK10864
272843006421	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
272843006422	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
272843006423	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
272843006424	Ribonuclease I [Translation, ribosomal structure and biogenesis]; Region: Rna; COG3719
272843006425	CAS motifs; other site
272843006426	active site
272843006427	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
272843006428	Phosphoglycerate kinase; Region: PGK; pfam00162
272843006429	substrate binding site [chemical binding]; other site
272843006430	hinge regions; other site
272843006431	ADP binding site [chemical binding]; other site
272843006432	catalytic site [active]
272843006433	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
272843006434	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
272843006435	active site
272843006436	intersubunit interface [polypeptide binding]; other site
272843006437	zinc binding site [ion binding]; other site
272843006438	Na+ binding site [ion binding]; other site
272843006439	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
272843006440	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
272843006441	O-Antigen ligase; Region: Wzy_C; pfam04932
272843006442	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
272843006443	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
272843006444	HD domain; Region: HD_4; pfam13328
272843006445	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
272843006446	synthetase active site [active]
272843006447	NTP binding site [chemical binding]; other site
272843006448	metal binding site [ion binding]; metal-binding site
272843006449	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
272843006450	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
272843006451	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
272843006452	TRAM domain; Region: TRAM; pfam01938
272843006453	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843006454	S-adenosylmethionine binding site [chemical binding]; other site
272843006455	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
272843006456	Recombination protein O N terminal; Region: RecO_N; pfam11967
272843006457	Recombination protein O C terminal; Region: RecO_C; pfam02565
272843006458	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
272843006459	RNA methyltransferase, RsmE family; Region: TIGR00046
272843006460	hypothetical protein; Validated; Region: PRK00228
272843006461	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
272843006462	enolase; Provisional; Region: eno; PRK00077
272843006463	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
272843006464	dimer interface [polypeptide binding]; other site
272843006465	metal binding site [ion binding]; metal-binding site
272843006466	substrate binding pocket [chemical binding]; other site
272843006467	CTP synthetase; Validated; Region: pyrG; PRK05380
272843006468	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
272843006469	Catalytic site [active]
272843006470	active site
272843006471	UTP binding site [chemical binding]; other site
272843006472	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
272843006473	active site
272843006474	putative oxyanion hole; other site
272843006475	catalytic triad [active]
272843006476	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
272843006477	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
272843006478	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
272843006479	hypothetical protein; Provisional; Region: PRK11820
272843006480	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
272843006481	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
272843006482	ribonuclease PH; Reviewed; Region: rph; PRK00173
272843006483	Ribonuclease PH; Region: RNase_PH_bact; cd11362
272843006484	hexamer interface [polypeptide binding]; other site
272843006485	active site
272843006486	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
272843006487	active site
272843006488	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
272843006489	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
272843006490	putative metal binding site [ion binding]; other site
272843006491	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
272843006492	HSP70 interaction site [polypeptide binding]; other site
272843006493	Predicted membrane protein [Function unknown]; Region: COG3647
272843006494	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
272843006495	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
272843006496	FMN binding site [chemical binding]; other site
272843006497	active site
272843006498	catalytic residues [active]
272843006499	substrate binding site [chemical binding]; other site
272843006500	dUMP phosphatase; Provisional; Region: PRK09449
272843006501	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843006502	motif II; other site
272843006503	hypothetical protein; Validated; Region: PRK06886
272843006504	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
272843006505	active site
272843006506	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
272843006507	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
272843006508	Sulfatase; Region: Sulfatase; cl17466
272843006509	hypothetical protein; Provisional; Region: PRK13689
272843006510	Nucleoid-associated protein [General function prediction only]; Region: COG3081
272843006511	nucleoid-associated protein NdpA; Validated; Region: PRK00378
272843006512	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
272843006513	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
272843006514	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
272843006515	active site
272843006516	phosphorylation site [posttranslational modification]
272843006517	intermolecular recognition site; other site
272843006518	dimerization interface [polypeptide binding]; other site
272843006519	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
272843006520	DNA binding site [nucleotide binding]
272843006521	two-component sensor protein; Provisional; Region: cpxA; PRK09470
272843006522	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
272843006523	dimerization interface [polypeptide binding]; other site
272843006524	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
272843006525	ATP binding site [chemical binding]; other site
272843006526	Mg2+ binding site [ion binding]; other site
272843006527	G-X-G motif; other site
272843006528	hypothetical protein; Provisional; Region: PRK11212
272843006529	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
272843006530	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
272843006531	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
272843006532	metal-binding site [ion binding]
272843006533	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
272843006534	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
272843006535	metal-binding site [ion binding]
272843006536	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
272843006537	Soluble P-type ATPase [General function prediction only]; Region: COG4087
272843006538	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
272843006539	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
272843006540	folate binding site [chemical binding]; other site
272843006541	NADP+ binding site [chemical binding]; other site
272843006542	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
272843006543	Uncharacterized conserved protein [Function unknown]; Region: COG2966
272843006544	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
272843006545	gamma-glutamyl kinase; Provisional; Region: PRK05429
272843006546	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
272843006547	nucleotide binding site [chemical binding]; other site
272843006548	homotetrameric interface [polypeptide binding]; other site
272843006549	putative phosphate binding site [ion binding]; other site
272843006550	putative allosteric binding site; other site
272843006551	PUA domain; Region: PUA; pfam01472
272843006552	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
272843006553	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
272843006554	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
272843006555	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
272843006556	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK06173
272843006557	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
272843006558	inhibitor-cofactor binding pocket; inhibition site
272843006559	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843006560	catalytic residue [active]
272843006561	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
272843006562	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
272843006563	substrate-cofactor binding pocket; other site
272843006564	pyridoxal 5'-phosphate binding site [chemical binding]; other site
272843006565	catalytic residue [active]
272843006566	Protein of unknown function (DUF452); Region: DUF452; pfam04301
272843006567	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
272843006568	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
272843006569	S-adenosylmethionine binding site [chemical binding]; other site
272843006570	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
272843006571	AAA domain; Region: AAA_26; pfam13500
272843006572	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
272843006573	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
272843006574	active site
272843006575	zinc binding site [ion binding]; other site
272843006576	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
272843006577	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
272843006578	Walker A/P-loop; other site
272843006579	ATP binding site [chemical binding]; other site
272843006580	Q-loop/lid; other site
272843006581	ABC transporter signature motif; other site
272843006582	Walker B; other site
272843006583	D-loop; other site
272843006584	H-loop/switch region; other site
272843006585	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
272843006586	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
272843006587	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
272843006588	Walker A/P-loop; other site
272843006589	ATP binding site [chemical binding]; other site
272843006590	Q-loop/lid; other site
272843006591	ABC transporter signature motif; other site
272843006592	Walker B; other site
272843006593	D-loop; other site
272843006594	H-loop/switch region; other site
272843006595	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
272843006596	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
272843006597	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
272843006598	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843006599	dimer interface [polypeptide binding]; other site
272843006600	conserved gate region; other site
272843006601	ABC-ATPase subunit interface; other site
272843006602	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
272843006603	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
272843006604	dimer interface [polypeptide binding]; other site
272843006605	conserved gate region; other site
272843006606	putative PBP binding loops; other site
272843006607	ABC-ATPase subunit interface; other site
272843006608	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
272843006609	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
272843006610	peptide binding site [polypeptide binding]; other site
272843006611	hypothetical protein; Provisional; Region: PRK11193
272843006612	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
272843006613	Fatty acid/phospholipid biosynthesis enzyme [Lipid metabolism]; Region: PlsX; COG0416
272843006614	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
272843006615	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
272843006616	dimer interface [polypeptide binding]; other site
272843006617	active site
272843006618	CoA binding pocket [chemical binding]; other site
272843006619	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
272843006620	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
272843006621	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
272843006622	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
272843006623	NAD(P) binding site [chemical binding]; other site
272843006624	homotetramer interface [polypeptide binding]; other site
272843006625	homodimer interface [polypeptide binding]; other site
272843006626	active site
272843006627	acyl carrier protein; Provisional; Region: acpP; PRK00982
272843006628	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
272843006629	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
272843006630	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
272843006631	transcription termination factor Rho; Provisional; Region: rho; PRK09376
272843006632	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
272843006633	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
272843006634	RNA binding site [nucleotide binding]; other site
272843006635	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
272843006636	multimer interface [polypeptide binding]; other site
272843006637	Walker A motif; other site
272843006638	ATP binding site [chemical binding]; other site
272843006639	Walker B motif; other site
272843006640	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
272843006641	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
272843006642	ATP binding site [chemical binding]; other site
272843006643	Mg++ binding site [ion binding]; other site
272843006644	motif III; other site
272843006645	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
272843006646	nucleotide binding region [chemical binding]; other site
272843006647	ATP-binding site [chemical binding]; other site
272843006648	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
272843006649	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
272843006650	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
272843006651	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
272843006652	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
272843006653	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
272843006654	rare lipoprotein A; Region: rlpA; TIGR00413
272843006655	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
272843006656	Sporulation related domain; Region: SPOR; pfam05036
272843006657	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
272843006658	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
272843006659	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
272843006660	hypothetical protein; Provisional; Region: PRK04998
272843006661	lipoate-protein ligase B; Provisional; Region: PRK14342
272843006662	Lipoate synthase [Coenzyme metabolism]; Region: LipA; COG0320
272843006663	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843006664	FeS/SAM binding site; other site
272843006665	Protein of unknown function, DUF417; Region: DUF417; pfam04224
272843006666	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
272843006667	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
272843006668	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
272843006669	homodimer interface [polypeptide binding]; other site
272843006670	NADP binding site [chemical binding]; other site
272843006671	substrate binding site [chemical binding]; other site
272843006672	Trans-activating transcriptional regulator; Region: TATR; pfam03430
272843006673	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
272843006674	Domain of unknown function (DUF4405); Region: DUF4405; pfam14358
272843006675	Transposase and inactivated derivatives, IS1 family [DNA replication, recombination, and repair]; Region: InsB; COG1662
272843006676	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
272843006677	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
272843006678	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
272843006679	Predicted metal-binding protein [General function prediction only]; Region: COG3019
272843006680	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
272843006681	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR2; cd08268
272843006682	putative NAD(P) binding site [chemical binding]; other site
272843006683	Helix-Turn-Helix DNA binding domain of the CadR and PbrR transcription regulators; Region: HTH_CadR-PbrR; cd04784
272843006684	Cd(II)/Pb(II)-responsive transcriptional regulator; Region: CadR-PbrR; TIGR02047
272843006685	DNA binding residues [nucleotide binding]
272843006686	dimer interface [polypeptide binding]; other site
272843006687	putative metal binding site [ion binding]; other site
272843006688	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
272843006689	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
272843006690	arsenical-resistance protein; Region: acr3; TIGR00832
272843006691	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
272843006692	ArsC family; Region: ArsC; pfam03960
272843006693	catalytic residues [active]
272843006694	Transcriptional regulator [Transcription]; Region: LysR; COG0583
272843006695	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
272843006696	dimerization interface [polypeptide binding]; other site
272843006697	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4688
272843006698	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
272843006699	active site
272843006700	catalytic residues [active]
272843006701	DNA binding site [nucleotide binding]
272843006702	Int/Topo IB signature motif; other site
272843006703	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
272843006704	active site
272843006705	catalytic residues [active]
272843006706	DNA binding site [nucleotide binding]
272843006707	Int/Topo IB signature motif; other site
272843006708	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
272843006709	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
272843006710	dimer interface [polypeptide binding]; other site
272843006711	ssDNA binding site [nucleotide binding]; other site
272843006712	tetramer (dimer of dimers) interface [polypeptide binding]; other site
272843006713	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
272843006714	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
272843006715	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843006716	ABC transporter signature motif; other site
272843006717	Walker B; other site
272843006718	D-loop; other site
272843006719	H-loop/switch region; other site
272843006720	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
272843006721	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
272843006722	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
272843006723	E-class dimer interface [polypeptide binding]; other site
272843006724	P-class dimer interface [polypeptide binding]; other site
272843006725	active site
272843006726	Cu2+ binding site [ion binding]; other site
272843006727	Zn2+ binding site [ion binding]; other site
272843006728	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
272843006729	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
272843006730	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
272843006731	exoribonuclease R; Provisional; Region: PRK11642
272843006732	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
272843006733	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
272843006734	RNB domain; Region: RNB; pfam00773
272843006735	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
272843006736	RNA binding site [nucleotide binding]; other site
272843006737	rod shape-determining protein MreB; Provisional; Region: PRK13927
272843006738	MreB and similar proteins; Region: MreB_like; cd10225
272843006739	nucleotide binding site [chemical binding]; other site
272843006740	Mg binding site [ion binding]; other site
272843006741	putative protofilament interaction site [polypeptide binding]; other site
272843006742	RodZ interaction site [polypeptide binding]; other site
272843006743	rod shape-determining protein MreC; Region: mreC; TIGR00219
272843006744	rod shape-determining protein MreC; Region: MreC; pfam04085
272843006745	rod shape-determining protein MreD; Region: MreD; cl01087
272843006746	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3787
272843006747	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
272843006748	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
272843006749	substrate binding site [chemical binding]; other site
272843006750	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
272843006751	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
272843006752	substrate binding site [chemical binding]; other site
272843006753	ligand binding site [chemical binding]; other site
272843006754	tartrate dehydrogenase; Region: TTC; TIGR02089
272843006755	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
272843006756	2-isopropylmalate synthase; Validated; Region: PRK00915
272843006757	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
272843006758	active site
272843006759	catalytic residues [active]
272843006760	metal binding site [ion binding]; metal-binding site
272843006761	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
272843006762	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
272843006763	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
272843006764	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
272843006765	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
272843006766	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
272843006767	motif II; other site
272843006768	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
272843006769	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
272843006770	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
272843006771	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
272843006772	putative NAD(P) binding site [chemical binding]; other site
272843006773	active site
272843006774	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
272843006775	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
272843006776	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
272843006777	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
272843006778	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
272843006779	Predicted metalloprotease [General function prediction only]; Region: COG2321
272843006780	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
272843006781	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
272843006782	BON domain; Region: BON; pfam04972
272843006783	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
272843006784	trigger factor; Provisional; Region: tig; PRK01490
272843006785	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
272843006786	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
272843006787	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
272843006788	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
272843006789	oligomer interface [polypeptide binding]; other site
272843006790	active site residues [active]
272843006791	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
272843006792	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
272843006793	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
272843006794	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843006795	Walker A motif; other site
272843006796	ATP binding site [chemical binding]; other site
272843006797	Walker B motif; other site
272843006798	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
272843006799	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
272843006800	Found in ATP-dependent protease La (LON); Region: LON; smart00464
272843006801	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
272843006802	Walker A motif; other site
272843006803	ATP binding site [chemical binding]; other site
272843006804	Walker B motif; other site
272843006805	arginine finger; other site
272843006806	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
272843006807	periplasmic folding chaperone; Provisional; Region: PRK10788
272843006808	SurA N-terminal domain; Region: SurA_N_3; cl07813
272843006809	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
272843006810	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
272843006811	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
272843006812	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
272843006813	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
272843006814	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
272843006815	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
272843006816	Walker A/P-loop; other site
272843006817	ATP binding site [chemical binding]; other site
272843006818	Q-loop/lid; other site
272843006819	ABC transporter signature motif; other site
272843006820	Walker B; other site
272843006821	D-loop; other site
272843006822	H-loop/switch region; other site
272843006823	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
272843006824	Walker A/P-loop; other site
272843006825	ATP binding site [chemical binding]; other site
272843006826	Q-loop/lid; other site
272843006827	ABC transporter signature motif; other site
272843006828	Walker B; other site
272843006829	D-loop; other site
272843006830	H-loop/switch region; other site
272843006831	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
272843006832	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
272843006833	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
272843006834	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
272843006835	E3 interaction surface; other site
272843006836	lipoyl attachment site [posttranslational modification]; other site
272843006837	HlyD family secretion protein; Region: HlyD_3; pfam13437
272843006838	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
272843006839	rRNA interaction site [nucleotide binding]; other site
272843006840	S8 interaction site; other site
272843006841	elongation factor Ts; Provisional; Region: tsf; PRK09377
272843006842	UBA/TS-N domain; Region: UBA; pfam00627
272843006843	Elongation factor TS; Region: EF_TS; pfam00889
272843006844	Elongation factor TS; Region: EF_TS; pfam00889
272843006845	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
272843006846	putative nucleotide binding site [chemical binding]; other site
272843006847	uridine monophosphate binding site [chemical binding]; other site
272843006848	homohexameric interface [polypeptide binding]; other site
272843006849	ribosome recycling factor; Reviewed; Region: frr; PRK00083
272843006850	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
272843006851	hinge region; other site
272843006852	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
272843006853	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
272843006854	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
272843006855	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
272843006856	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
272843006857	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
272843006858	catalytic residue [active]
272843006859	putative FPP diphosphate  binding site; other site
272843006860	putative FPP binding hydrophobic cleft; other site
272843006861	dimer interface [polypeptide binding]; other site
272843006862	putative IPP diphosphate binding site; other site
272843006863	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
272843006864	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
272843006865	zinc metallopeptidase RseP; Provisional; Region: PRK10779
272843006866	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
272843006867	active site
272843006868	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
272843006869	protein binding site [polypeptide binding]; other site
272843006870	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
272843006871	protein binding site [polypeptide binding]; other site
272843006872	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
272843006873	putative substrate binding region [chemical binding]; other site
272843006874	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
272843006875	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
272843006876	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
272843006877	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
272843006878	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
272843006879	Surface antigen; Region: Bac_surface_Ag; pfam01103
272843006880	periplasmic chaperone; Provisional; Region: PRK10780
272843006881	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
272843006882	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
272843006883	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
272843006884	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
272843006885	trimer interface [polypeptide binding]; other site
272843006886	active site
272843006887	UDP-GlcNAc binding site [chemical binding]; other site
272843006888	lipid binding site [chemical binding]; lipid-binding site
272843006889	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
272843006890	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
272843006891	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
272843006892	active site
272843006893	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
272843006894	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
272843006895	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
272843006896	RNA/DNA hybrid binding site [nucleotide binding]; other site
272843006897	active site
272843006898	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
272843006899	transmembrane helices; other site
272843006900	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
272843006901	TrkA-C domain; Region: TrkA_C; pfam02080
272843006902	TrkA-C domain; Region: TrkA_C; pfam02080
272843006903	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
272843006904	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
272843006905	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
272843006906	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
272843006907	putative acyl-acceptor binding pocket; other site
272843006908	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
272843006909	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
272843006910	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
272843006911	MPT binding site; other site
272843006912	trimer interface [polypeptide binding]; other site
272843006913	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
272843006914	Nitrogen regulatory protein P-II; Region: P-II; smart00938
272843006915	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
272843006916	Domain of unknown function DUF20; Region: UPF0118; pfam01594
272843006917	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
272843006918	binding surface
272843006919	TPR motif; other site
272843006920	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
272843006921	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
272843006922	binding surface
272843006923	TPR motif; other site
272843006924	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
272843006925	binding surface
272843006926	TPR motif; other site
272843006927	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
272843006928	binding surface
272843006929	TPR motif; other site
272843006930	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
272843006931	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
272843006932	FeS/SAM binding site; other site
272843006933	TPR repeat; Region: TPR_11; pfam13414
272843006934	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
272843006935	binding surface
272843006936	TPR motif; other site
272843006937	TPR repeat; Region: TPR_11; pfam13414
272843006938	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
272843006939	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
272843006940	non-specific DNA binding site [nucleotide binding]; other site
272843006941	salt bridge; other site
272843006942	sequence-specific DNA binding site [nucleotide binding]; other site
272843006943	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
272843006944	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
272843006945	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
272843006946	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
272843006947	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
272843006948	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
272843006949	dimer interface [polypeptide binding]; other site
272843006950	motif 1; other site
272843006951	active site
272843006952	motif 2; other site
272843006953	motif 3; other site
272843006954	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
272843006955	anticodon binding site; other site
272843006956	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
272843006957	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
272843006958	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
272843006959	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
272843006960	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
272843006961	active site
272843006962	metal binding site [ion binding]; metal-binding site
272843006963	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872