-- dump date 20140619_232405 -- class Genbank::CDS -- table cds_note -- id note YP_003257477.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_003257478.1 binds the polymerase to DNA and acts as a sliding clamp YP_003257479.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_003257480.1 negatively supercoils closed circular double-stranded DNA YP_003257481.1 PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_0005 major facilitator superfamily MFS_1 YP_003257482.1 PFAM: chemotaxis sensory transducer; Cache domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_0007 methyl-accepting chemotaxis sensory transducer with cache sensor YP_003257483.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA4436 LacI family transcriptional regulator YP_003257484.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: pct:PC1_0009 phosphotransferase system lactose/cellobiose-specific IIsubunit beta YP_003257485.1 KEGG: eca:ECA4434 PTS system, IIBC component; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC YP_003257486.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIsubunit alpha; KEGG: eca:ECA4433 pts system, cellobiose-specific IIA component YP_003257487.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA4432 6-phospho-beta-glucosidase YP_003257488.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_003257489.1 KEGG: pmr:PMI1798 lipoprotein YP_003257490.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA4427 LysR family transcriptional regulator YP_003257491.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA4426 extracellular solute-binding protein YP_003257492.1 PFAM: dihydrodipicolinate synthetase; KEGG: eca:ECA4425 dihydrodipicolinate synthetase YP_003257493.1 PFAM: inosine/uridine-preferring nucleoside hydrolase; KEGG: pct:PC1_0017 inosine/uridine-preferring nucleoside hydrolase YP_003257494.1 PFAM: inosine/uridine-preferring nucleoside hydrolase; KEGG: pct:PC1_0018 inosine/uridine-preferring nucleoside hydrolase YP_003257495.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_0019 binding-protein-dependent transport systems inner membrane component YP_003257496.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4421 ABC transporter permease YP_003257497.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_0021 ABC transporter related YP_003257498.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA4419 galactonate operon transcriptional repressor YP_003257499.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: eca:ECA4418 2-dehydro-3-deoxygalactonokinase YP_003257500.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_003257501.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA4416 galactonate dehydratase YP_003257503.1 TIGRFAM: d-galactonate transporter; phosphoglycerate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4415 D-galactonate transporter YP_003257504.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA4414 hypothetical protein YP_003257505.1 part of the ABC type transporter SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_003257506.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4412 aliphatic sulfonates transport permease YP_003257507.1 catalyzes the release of sulfite from alkanesulfonates YP_003257508.1 part of the ABC type transporter SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_003257509.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: pct:PC1_0028 phosphotransferase system lactose/cellobiose-specific IIsubunit beta YP_003257510.1 KEGG: eca:ECA4408 PTS system EIIC component; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC YP_003257511.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA4407 glycosyl hydrolase YP_003257512.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA4406 hypothetical protein YP_003257513.1 KEGG: eca:ECA4405 hypothetical protein YP_003257514.1 PFAM: protein of unknown function DUF1375; KEGG: eca:ECA4404 hypothetical protein YP_003257515.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_003257516.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_003257518.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; TrkA-C domain protein; KEGG: eca:ECA4401 hypothetical protein YP_003257519.1 TIGRFAM: anion transporter; PFAM: sodium/sulfate symporter; citrate transporter; KEGG: eca:ECA4400 sodium:sulfate symporter YP_003257520.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_003257521.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_003257522.1 KEGG: eca:ECA4396 hypothetical protein YP_003257523.1 PFAM: citrate carrier protein; KEGG: eca:ECA4395 Na(+)-malate symporter YP_003257524.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA4394 periplasmic dipeptide transporter YP_003257525.1 transports peptides consisting of two or three amino acids YP_003257526.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4392 dipeptide transporter YP_003257527.1 DppD and DppF are the ATP-binding proteins of the ABC dipeptide transporter DppABCDF YP_003257528.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_003257529.1 KEGG: esa:ESA_03902 hypothetical protein YP_003257530.1 KEGG: pct:PC1_0050 hypothetical protein YP_003257531.1 KEGG: pen:PSEEN0864 hypothetical protein YP_003257533.1 KEGG: pen:PSEEN2319 hypothetical protein YP_003257536.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: eca:ECA4275 hypothetical protein YP_003257537.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_003257538.1 KEGG: eca:ECA4385 hypothetical protein YP_003257539.1 catalyzes the formation of D-tagaturonate from D-altronate YP_003257540.1 PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; KEGG: pct:PC1_0059 alcohol dehydrogenase GroES YP_003257541.1 PFAM: GntR family transcriptional regulator; KEGG: eca:ECA4381 DNA-binding protein YP_003257542.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4380 sugar transporter YP_003257543.1 KEGG: eca:ECA4379 gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_003257544.1 KEGG: smt:Smal_3939 hypothetical protein YP_003257545.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_003257546.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_003257547.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_003257548.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_003257549.1 TIGRFAM: cellulose synthase operon protein YhjQ; PFAM: YhjQ family protein; KEGG: eca:ECA4369 hypothetical protein YP_003257550.1 KEGG: pct:PC1_0078 hypothetical protein YP_003257551.1 TIGRFAM: cellulose biosynthesis protein BcsE; KEGG: pct:PC1_0079 cellulose biosynthesis protein BcsE YP_003257552.1 TIGRFAM: celllulose biosynthesis operon protein BcsF/YhjT; KEGG: eca:ECA4365 hypothetical protein YP_003257553.1 TIGRFAM: cellulose synthase operon protein YhjU; KEGG: pct:PC1_0081 cellulose synthase operon protein YhjU YP_003257554.1 PFAM: histidine kinase HAMP region domain protein; GGDEF domain containing protein; SMART: GGDEF domain containing protein; KEGG: eca:ECA4363 hypothetical protein YP_003257555.1 involved in the transport of C4-dicarboxylates across the membrane YP_003257556.1 PFAM: peptidase M16 domain protein; KEGG: pct:PC1_0084 peptidase M16 domain protein YP_003257557.1 PFAM: PfkB domain protein; KEGG: pct:PC1_0086 PfkB domain protein YP_003257558.1 TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: pct:PC1_0087 ribonuclease YP_003257559.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4358 major facilitator superfamily transporter YP_003257560.1 KEGG: pct:PC1_0089 hypothetical protein YP_003257561.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF165; KEGG: pct:PC1_0091 hypothetical protein YP_003257562.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_003257563.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_003257564.1 PFAM: YhhN family protein; KEGG: pct:PC1_0094 YhhN family protein YP_003257565.1 PFAM: Domain of unknown function DUF1820; KEGG: eca:ECA4350 hypothetical protein YP_003257566.1 PFAM: protein of unknown function DUF1145; KEGG: pct:PC1_0097 hypothetical protein YP_003257567.1 catalyzes the methylation of 16S rRNA at position G966 YP_003257568.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_003257569.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_003257570.1 ABC transporter membrane protein YP_003257571.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_003257572.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA4342 acetyltransferase YP_003257573.1 PFAM: extracellular ligand-binding receptor; KEGG: eca:ECA4341 leucine-specific binding protein YP_003257574.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_003257575.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003257576.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003257577.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transporter; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003257578.1 PFAM: aminotransferase class I and II; KEGG: eca:ECA4336 aminotransferase YP_003257579.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_0110 methyl-accepting chemotaxis sensory transducer YP_003257580.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_0111 methyl-accepting chemotaxis sensory transducer YP_003257581.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4333 methyl-accepting chemotaxis protein YP_003257582.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_0113 methyl-accepting chemotaxis sensory transducer YP_003257583.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_003257584.1 PFAM: xylose isomerase; KEGG: pct:PC1_0115 hydroxypyruvate isomerase YP_003257585.1 PFAM: class II aldolase/adducin family protein; KEGG: pct:PC1_0116 L-fuculose-phosphate aldolase YP_003257586.1 PFAM: type III effector Hrp-dependent outers; KEGG: pct:PC1_0117 type III effector Hrp-dependent outers YP_003257587.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: pct:PC1_0118 2-hydroxy-3-oxopropionate reductase YP_003257588.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: eca:ECA4325 DeoR family transcriptional regulator YP_003257589.1 PFAM: protein of unknown function DUF1778; KEGG: pct:PC1_0122 hypothetical protein YP_003257590.1 PFAM: plasmid stabilization system; KEGG: pct:PC1_0123 plasmid stabilization system YP_003257591.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: pct:PC1_0124 addiction module antidote protein, CopG/Arc/MetJ family YP_003257592.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_003257593.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_003257594.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_003257595.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_003257596.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_003257597.1 PFAM: hypothetical protein; KEGG: eca:ECA4317 transporter YP_003257598.1 KEGG: eca:ECA4316 hypothetical protein YP_003257599.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: pct:PC1_0132 tRNA/rRNA methyltransferase (SpoU) YP_003257600.1 KEGG: pct:PC1_0133 hypothetical protein YP_003257601.1 KEGG: pct:PC1_0134 hypothetical protein YP_003257602.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_003257603.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_003257604.1 KEGG: eca:ECA4310 stress resistance protein YP_003257605.1 KEGG: pmr:PMI0561 hypothetical protein YP_003257606.1 PFAM: ATPase associated with various cellular activities AAA_5; KEGG: pmr:PMI0560 ATPase YP_003257607.1 KEGG: pmr:PMI0559 hypothetical protein YP_003257608.1 PFAM: von Willebrand factor A; SMART: von Willebrand factor A; KEGG: pmr:PMI0558 hypothetical protein YP_003257609.1 PFAM: hypothetical protein; KEGG: pmr:PMI0557 hypothetical protein YP_003257610.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4309 sugar efflux transporter YP_003257611.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_003257612.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_003257613.1 PFAM: Integrase catalytic region; KEGG: net:Neut_2192 integrase catalytic subunit YP_003257614.1 PFAM: transposase IS3/IS911 family protein; KEGG: har:HEAR2248 transposase YP_003257615.1 KEGG: pay:PAU_00937 hypothetical protein YP_003257616.1 TIGRFAM: hypothetical protein; PFAM: YD repeat-containing protein; KEGG: eca:ECA2869 rhs protein YP_003257618.1 KEGG: spc:Sputcn32_3204 hypothetical protein YP_003257620.1 KEGG: efe:EFER_2927 global regulatory protein YP_003257621.1 KEGG: nmn:NMCC_0593 hypothetical protein YP_003257622.1 KEGG: spc:Sputcn32_1261 hypothetical protein YP_003257623.1 KEGG: dze:Dd1591_2561 hypothetical protein YP_003257624.1 KEGG: dze:Dd1591_2562 hypothetical protein YP_003257625.1 KEGG: eum:ECUMN_0782 hypothetical protein YP_003257626.1 KEGG: esa:ESA_03894 hypothetical protein YP_003257628.1 KEGG: eca:ECA3411 hypothetical protein YP_003257629.1 TIGRFAM: N-carbamoylputrescine amidase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eca:ECA4274 carbon-nitrogen hydrolase YP_003257630.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_003257631.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_003257632.1 PFAM: protein of unknown function DUF1454; KEGG: pct:PC1_0155 hypothetical protein YP_003257633.1 PFAM: protein of unknown function DUF805; KEGG: eca:ECA4270 hypothetical protein YP_003257634.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: eca:ECA4269 ferredoxin-NADP reductase YP_003257635.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_003257636.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY-like; KEGG: eca:ECA4267 glycerol kinase YP_003257637.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: pct:PC1_0160 MIP family channel protein YP_003257638.1 PFAM: protein of unknown function DUF904; KEGG: eca:ECA4265 hypothetical protein YP_003257639.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_003257640.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_003257641.1 heat shock protein involved in degradation of misfolded proteins YP_003257642.1 heat shock protein involved in degradation of misfolded proteins YP_003257643.1 TIGRFAM: cell division protein FtsN; PFAM: sporulation domain protein; KEGG: eca:ECA4260 cell division protein FtsN YP_003257644.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_003257645.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_003257646.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_003257647.1 PFAM: transporter permease; KEGG: pct:PC1_0173 transporter permease YP_003257648.1 PFAM: periplasmic binding protein; KEGG: pct:PC1_0174 periplasmic binding protein YP_003257649.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA4254 iron(III) ABC transporter ATP-binding protein YP_003257650.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_003257651.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_003257652.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_003257653.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_003257655.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_003257656.1 catalyzes the conversion of NADPH to NADH YP_003257657.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_003257658.1 PFAM: protein of unknown function DUF1422; KEGG: eca:ECA4240 hypothetical protein YP_003257659.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_003257660.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_003257661.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_003257662.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_003257663.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_003257664.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_003257665.1 TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain protein; elongation factor Tu domain 2 protein; KEGG: pct:PC1_3827 translation elongation factor Tu YP_003257666.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_003257667.1 Modulates Rho-dependent transcription termination YP_003257668.1 binds directly to 23S ribosomal RNA YP_003257669.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_003257670.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_003257671.1 TIGRFAM: ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12; KEGG: pct:PC1_0204 ribosomal protein L7/L12 YP_003257672.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; subunit beta is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_003257673.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_003257674.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA0225 shikimate transporter YP_003257675.1 PFAM: protein of unknown function DUF1127; KEGG: pct:PC1_0208 hypothetical protein YP_003257676.1 PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA0227 GntR family transcriptional regulator YP_003257677.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_003257678.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_003257679.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_003257680.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF YP_003257681.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_003257682.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_003257683.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_003257684.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_003257685.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_003257686.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_003257687.1 PFAM: protein of unknown function DUF416; KEGG: pct:PC1_0221 hypothetical protein YP_003257688.1 histone-like DNA-binding protein YP_003257689.1 PFAM: protein of unknown function DUF1481; KEGG: eca:ECA0239 lipoprotein YP_003257690.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_003257691.1 involved in de novo purine biosynthesis YP_003257692.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_0226 ABC transporter YP_003257693.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0243 L-amino acid ABC transporter permease YP_003257694.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0244 L-amino acid ABC transporter permease YP_003257695.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: pct:PC1_0229 extracellular solute-binding protein family 3 YP_003257696.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0246 amino-acid transporter permease protein YP_003257697.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA0247 cystine-binding periplasmic protein YP_003257698.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: eca:ECA0251 endonuclease/exonuclease/phosphatase family protein YP_003257699.1 KEGG: yen:YE2358 hypothetical protein YP_003257700.1 KEGG: pay:PAU_02290 hypothetical protein YP_003257701.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_003257702.1 TIGRFAM: hypothetical protein; PFAM: dihydrouridine synthase; KEGG: eca:ECA0256 tRNA-dihydrouridine synthase B YP_003257703.1 PFAM: carbonic anhydrase; KEGG: eca:ECA0257 carbonic anhydrase YP_003257704.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_003257705.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_003257706.1 PFAM: protein of unknown function DUF997; KEGG: pct:PC1_0241 hypothetical protein YP_003257707.1 PFAM: TOBE domain protein; KEGG: pct:PC1_0242 TOBE domain protein YP_003257708.1 PFAM: periplasmic binding protein; KEGG: pmr:PMI2675 iron compound ABC transporter substrate-binding protein YP_003257709.1 PFAM: transporter permease; ABC-3 protein; KEGG: pmr:PMI2676 iron compound ABC transporter permease YP_003257710.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pmr:PMI2677 iron compound ABC transporter ATP-binding protein YP_003257711.1 KEGG: pmr:PMI2678 hypothetical protein YP_003257712.1 involved in molybdenum transport YP_003257713.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cko:CKO_01203 hypothetical protein YP_003257714.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_003257715.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_003257716.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_003257717.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_003257718.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_003257721.1 TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: eca:ECA0265 zinc-binding oxidoreductase YP_003257722.1 KEGG: pct:PC1_0250 hypothetical protein YP_003257723.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_003257724.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_003257725.1 part of cell wall structural complex MreBCD; transmembrane component YP_003257726.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_003257727.1 involved in the processing of the 5'end of 16S rRNA YP_003257728.1 KEGG: eca:ECA0272 hypothetical protein YP_003257729.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_003257730.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0276 DNA-binding transcriptional regulator YP_003257731.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_003257732.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_003257733.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_003257734.1 PFAM: protein of unknown function DUF615; KEGG: pct:PC1_0266 hypothetical protein YP_003257735.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_003257736.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_003257737.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: pct:PC1_0270 phosphotransferase system, phosphocarrier protein HPr YP_003257738.1 PFAM: conserved hypothetical protein; KEGG: pct:PC1_0271 hypothetical protein YP_003257739.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: eca:ECA0286 PTS IIA-like nitrogen-regulatory protein PtsN YP_003257740.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_003257741.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_003257742.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_0275 ABC transporter YP_003257743.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_003257744.1 PFAM: protein of unknown function DUF1239; KEGG: eca:ECA0291 hypothetical protein YP_003257745.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_003257746.1 KEGG: eca:ECA0293 D-arabinose 5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein YP_003257747.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_003257748.1 ATP-binding subunit of a ABC toluene efflux transporter YP_003257749.1 PFAM: protein of unknown function DUF140; KEGG: pct:PC1_0282 hypothetical protein YP_003257750.1 PFAM: hypothetical protein; KEGG: pct:PC1_0283 mammalian cell entry related domain protein YP_003257751.1 PFAM: toluene tolerance family protein; KEGG: eca:ECA0298 hypothetical protein YP_003257752.1 KEGG: eca:ECA0299 hypothetical protein YP_003257753.1 PFAM: BolA family protein; KEGG: pct:PC1_0286 BolA family protein YP_003257754.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_003257755.1 KEGG: eca:ECA0302 serine endoprotease; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein YP_003257756.1 KEGG: eca:ECA0303 exported protease; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein YP_003257757.1 PFAM: protein of unknown function DUF1043; KEGG: pct:PC1_0290 hypothetical protein YP_003257758.1 PFAM: AFG1-family ATPase; KEGG: pct:PC1_0291 AFG1-family ATPase YP_003257759.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_003257760.1 forms a direct contact with the tRNA during translation YP_003257761.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_003257762.1 PFAM: stringent starvation protein B; KEGG: eca:ECA0309 ClpXP protease specificity-enhancing factor YP_003257763.1 TIGRFAM: acetoin reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eca:ECA0310 acetoin reductase YP_003257764.1 glutamate synthase is composed of subunits alpha and beta; subunit beta is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the subunit alpha, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_003257765.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_003257766.1 KEGG: eca:ECA0313 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB YP_003257767.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_003257768.1 PFAM: ThiJ/PfpI domain protein; KEGG: pct:PC1_0302 ThiJ/PfpI domain protein YP_003257769.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_003257770.1 KEGG: pct:PC1_0304 hypothetical protein YP_003257771.1 PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: eca:ECA0319 hypothetical protein YP_003257772.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_003257773.1 PFAM: protein of unknown function UPF0102; KEGG: pct:PC1_0307 hypothetical protein YP_003257774.1 PFAM: LppC family lipoprotein; KEGG: pct:PC1_0308 LppC family lipoprotein YP_003257775.1 PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: eca:ECA0323 tetrapyrrole methylase YP_003257776.1 KEGG: yen:YE1937 hypothetical protein YP_003257777.1 KEGG: yps:YPTB0567 hypothetical protein YP_003257778.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: eca:ECA0325 plasmid stability protein YP_003257779.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: eca:ECA0326 plasmid stability protein YP_003257780.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_003257781.1 PFAM: glutathionylspermidine synthase; KEGG: eca:ECA0328 glutathionylspermidine synthase YP_003257782.1 PFAM: protein of unknown function DUF1190; KEGG: pct:PC1_0312 hypothetical protein YP_003257783.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_003257784.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_003257785.1 PFAM: protein of unknown function DUF1249; KEGG: pct:PC1_0316 hypothetical protein YP_003257786.1 PFAM: calcineurin phosphoesterase; metallophosphoesterase; KEGG: pct:PC1_0317 calcineurin phosphoesterase domain protein YP_003257787.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_003257788.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_003257789.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pct:PC1_0321 LysR family transcriptional regulator YP_003257790.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: eca:ECA0337 modulator of drug activity B YP_003257791.1 KEGG: eca:ECA0338 hypothetical protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II YP_003257792.1 PFAM: ketose-bisphosphate aldolase class-II; KEGG: eca:ECA0339 sugar-bisphosphate aldolase YP_003257793.1 TIGRFAM: PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; KEGG: eca:ECA0340 PTS system, IIBC component YP_003257794.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose-specific IIB subunit; KEGG: pct:PC1_0326 PTS system, fructose-specific, IIB subunnit YP_003257795.1 TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: pct:PC1_0327 PTS IIA-like nitrogen-regulatory protein PtsN YP_003257796.1 PFAM: PRD domain protein; Helix-turn-helix type 11 domain protein; M trans-acting positive regulator; regulatory protein DeoR; KEGG: eca:ECA0343 PTS system regulatory protein YP_003257797.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pct:PC1_0329 TonB-dependent receptor YP_003257798.1 KEGG: pct:PC1_0331 hypothetical protein YP_003257799.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_003257800.1 KEGG: pct:PC1_0333 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase YP_003257801.1 PFAM: multicopper oxidase type 3; multicopper oxidase type 2; KEGG: pct:PC1_0334 multicopper oxidase type 3 YP_003257802.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein Crp; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA0348 GntR family transcriptional regulator YP_003257803.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_003257804.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: pct:PC1_0054 type VI secretion system effector, Hcp1 family YP_003257805.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA2867 rhs accessory genetic element YP_003257806.1 PFAM: Domain of unknown function DUF1795; KEGG: eta:ETA_30010 hypothetical protein YP_003257807.1 TIGRFAM: hypothetical protein; PFAM: RHS protein; PAAR repeat-containing protein; hypothetical protein; KEGG: eta:ETA_08660 rhs family protein YP_003257809.1 PFAM: RHS protein; KEGG: eta:ETA_30000 membrane-bound sugar-binding protein YP_003257812.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: sfv:SFV_0629 hypothetical protein YP_003257813.1 KEGG: plu:plu3590 hypothetical protein YP_003257814.1 KEGG: bxe:Bxe_B1285 hypothetical protein YP_003257815.1 KEGG: bxe:Bxe_B1286 hypothetical protein YP_003257817.1 PFAM: guanine-specific ribonuclease N1 and T1; RHS protein; KEGG: eta:ETA_30000 membrane-bound sugar-binding protein YP_003257818.1 PFAM: Barstar (barnase inhibitor); KEGG: rlg:Rleg_3292 barstar (barnase inhibitor) YP_003257819.1 KEGG: pfl:PFL_2671 hypothetical protein YP_003257820.1 KEGG: esa:ESA_03890 hypothetical protein YP_003257821.1 KEGG: pct:PC1_0051 hypothetical protein YP_003257824.1 KEGG: eca:ECA2869 rhs protein YP_003257825.1 KEGG: bcj:BCAL1298 hypothetical protein YP_003257826.1 KEGG: shw:Sputw3181_1019 hypothetical protein YP_003257827.1 KEGG: plu:plu0353 hypothetical protein YP_003257828.1 KEGG: pen:PSEEN4592 hypothetical protein YP_003257829.1 PFAM: transposase IS3/IS911 family protein; KEGG: ent:Ent638_4321 transposase IS3/IS911 family protein YP_003257830.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: eca:ECA0350 iron-containing alcohol dehydrogenase YP_003257831.1 PFAM: nitroreductase; KEGG: pct:PC1_0338 nitroreductase YP_003257832.1 PFAM: AraC-type transcriptional regulator; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA0352 AraC family transcription regulator YP_003257833.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA0353 DedA family membrane protein YP_003257834.1 catalyzes the formation of L-homocysteine from cystathionine YP_003257835.1 TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: eca:ECA0355 DedA family membrane protein YP_003257836.1 PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: eca:ECA0356 hypothetical protein YP_003257837.1 TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: extracellular solute-binding protein, family 7, bacteria; KEGG: eca:ECA0357 substrate-binding periplasmic protein YP_003257838.1 TIGRFAM: tonB-system energizer ExbB; PFAM: MotA/TolQ/ExbB proton channel; KEGG: pct:PC1_0345 TonB-system energizer ExbB YP_003257839.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_003257840.1 KEGG: ecr:ECIAI1_4101 hypothetical protein YP_003257841.1 KEGG: eca:ECA0360 sucrose operon repressor; TIGRFAM: D-fructose-responsive transcription factor; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI YP_003257842.1 KEGG: eca:ECA0361 sucrose-6-phosphate hydrolase; TIGRFAM: sucrose-6-phosphate hydrolase; PFAM: glycosyl hydrolase family 32 domain protein; SMART: glycoside hydrolase family 32 YP_003257843.1 TIGRFAM: PTS system, sucrose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PTS system, maltose and glucose-specific subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: eca:ECA0362 PTS system, sucrose-specific IIBC component YP_003257844.1 PFAM: porin; KEGG: pct:PC1_0350 porin YP_003257845.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least YP_003257846.1 PFAM: protein of unknown function DUF583; KEGG: eca:ECA0365 hypothetical protein YP_003257847.1 TIGRFAM: CRISPR-associated helicase Cas3; SMART: DEAD/DEAH box helicase; KEGG: dda:Dd703_3591 CRISPR-associated helicase Cas3 YP_003257848.1 TIGRFAM: CRISPR-associated protein, Cse1 family; PFAM: CRISPR-associated protein Cse1; KEGG: dda:Dd703_3590 CRISPR-associated protein, CSE1 family YP_003257849.1 TIGRFAM: CRISPR-associated protein, Cse2 family; PFAM: CRISPR-associated protein Cse2; KEGG: dda:Dd703_3589 CRISPR-associated protein, CSE2 family YP_003257850.1 TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CRISPR-associated protein CT1975; KEGG: dda:Dd703_3588 CRISPR-associated protein, CSE4 family YP_003257851.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein CT1976; KEGG: dda:Dd703_3587 CRISPR-associated protein Cas5 family YP_003257852.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: dda:Dd703_3586 CRISPR-associated protein, CSE3 family YP_003257853.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; KEGG: dda:Dd703_3585 CRISPR-associated protein Cas1 YP_003257854.1 TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR-associated protein Cas2; KEGG: dda:Dd703_3584 CRISPR-associated protein Cas2 YP_003257855.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: esa:ESA_00803 hypothetical protein YP_003257856.1 PFAM: plasmid stabilization system; KEGG: ypb:YPTS_3250 plasmid stabilization system protein YP_003257857.1 PFAM: protein of unknown function DUF2136; KEGG: eca:ECA0366 hypothetical protein YP_003257858.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: eca:ECA0367 DNA-binding protein YP_003257860.1 KEGG: pct:PC1_0353 hypothetical protein YP_003257861.1 PFAM: pyridoxal-dependent decarboxylase; KEGG: eca:ECA0369 pyridoxal-dependent decarboxylase YP_003257862.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0370 hypothetical protein YP_003257863.1 PFAM: helix-turn-helix HxlR type; KEGG: pct:PC1_0356 HxlR family transcriptional regulator YP_003257864.1 KEGG: eca:ECA0372 hypothetical protein YP_003257865.1 KEGG: eca:ECA0373 hypothetical protein YP_003257866.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_003257867.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_003257868.1 TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: pct:PC1_0365 endoribonuclease L-PSP YP_003257869.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_003257870.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_003257871.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA0383 hypothetical protein YP_003257872.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: pct:PC1_0371 LuxR family transcriptional regulator YP_003257873.1 PFAM: hypothetical protein; SMART: regulatory protein LuxR; KEGG: pct:PC1_0372 PAS/PAC sensor protein YP_003257874.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_003257875.1 PFAM: protein of unknown function DUF1260; KEGG: pct:PC1_0375 hypothetical protein YP_003257876.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0386 acetyltransferase YP_003257877.1 PFAM: protein of unknown function DUF898 transmembrane; KEGG: eca:ECA0387 hypothetical protein YP_003257878.1 PFAM: peptidase M48 Ste24p; KEGG: pct:PC1_0378 peptidase M48 Ste24p YP_003257879.1 PFAM: alpha/beta hydrolase fold; KEGG: pct:PC1_0379 homoserine O-acetyltransferase YP_003257880.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_0380 methyl-accepting chemotaxis sensory transducer YP_003257881.1 PFAM: polypeptide-transport-associated domain protein ShlB-type; Hemolysin activator HlyB domain protein; KEGG: eca:ECA0391 activator or transporter protein of haemolysin-like protein YP_003257882.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentous haemagglutinin domain protein; Haemagluttinin repeat-containing protein; protein of unknown function DUF638 hemagglutinin/hemolysin KEGG: pct:PC1_2330 filamentous hemagglutinin family outer membrane protein YP_003257884.1 KEGG: pay:PAU_03360 hypothetical protein YP_003257885.1 PFAM: phosphotransferase KptA/Tpt1; KEGG: eca:ECA0395 RNA 2'-phosphotransferase YP_003257886.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: eca:ECA4289 hypothetical protein YP_003257887.1 KEGG: rec:RHECIAT_PB0000188 hypothetical protein YP_003257888.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: mlo:mlr3188 hypothetical protein YP_003257889.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_003257890.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_003257891.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_003257892.1 PFAM: permease YjgP/YjgQ family protein; KEGG: pct:PC1_0389 permease YjgP/YjgQ family protein YP_003257893.1 PFAM: permease YjgP/YjgQ family protein; KEGG: pct:PC1_0390 permease YjgP/YjgQ family protein YP_003257894.1 PFAM: integrase; KEGG: dze:Dd1591_3702 integrase YP_003257896.1 PFAM: Insertion element protein; KEGG: sdy:SDY_P213 iso-IS1 ORF1 YP_003257897.1 PFAM: protein of unknown function DUF87; KEGG: smt:Smal_1674 protein of unknown function DUF87 YP_003257898.1 KEGG: smt:Smal_1675 hypothetical protein YP_003257899.1 PFAM: DNA methylase N-4/N-6; KEGG: sek:SSPA3985 DNA methyltransferase SptAIM; protects DNA against PvuII endonuclease YP_003257900.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: sek:SSPA3986 subunit S of type I restriction-modification system YP_003257901.1 KEGG: sek:SSPA3987 subunit R of type I restriction-modification system YP_003257903.1 KEGG: ypy:YPK_3136 hypothetical protein YP_003257904.1 KEGG: sbl:Sbal_0630 hypothetical protein YP_003257906.1 KEGG: ent:Ent638_4231 hypothetical protein YP_003257907.1 KEGG: ent:Ent638_4232 hypothetical protein YP_003257908.1 PFAM: protein of unknown function DUF323; KEGG: ent:Ent638_4233 hypothetical protein YP_003257909.1 PFAM: protein of unknown function DUF214; KEGG: ent:Ent638_4234 hypothetical protein YP_003257910.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ent:Ent638_4235 ABC transporter YP_003257911.1 PFAM: von Willebrand factor A; KEGG: ent:Ent638_4236 von Willebrand factor, type A YP_003257912.1 KEGG: ent:Ent638_4237 hypothetical protein YP_003257913.1 PFAM: virulence effector, SrfC; KEGG: ent:Ent638_4238 hypothetical protein YP_003257914.1 PFAM: virulence protein SrfB; KEGG: ent:Ent638_4239 virulence protein SrfB YP_003257915.1 KEGG: ent:Ent638_4240 hypothetical protein YP_003257916.1 PFAM: von Willebrand factor A; SMART: von Willebrand factor A; KEGG: ent:Ent638_4241 von Willebrand factor, type A YP_003257917.1 PFAM: cupin; SMART: transcription factor jumonji jmjC domain protein; KEGG: pct:PC1_0392 cupin 4 family protein YP_003257918.1 PFAM: secretory lipase; KEGG: eca:ECA0421 exported lipase YP_003257919.1 PFAM: ABC transporter; KEGG: pct:PC1_0394 ABC-2 type transporter YP_003257920.1 KEGG: eca:ECA0423 hypothetical protein YP_003257921.1 KEGG: eca:ECA0424 hypothetical protein YP_003257922.1 PFAM: outer membrane efflux protein; KEGG: pct:PC1_0397 outer membrane efflux protein YP_003257923.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cko:CKO_00841 hypothetical protein YP_003257924.1 catalyzes the formation of fumarate from aspartate YP_003257925.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pct:PC1_0399 LysR family transcriptional regulator YP_003257926.1 KEGG: pct:PC1_0400 hypothetical protein YP_003257927.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: pen:PSEEN5219 Cro/CI family transcriptional regulator YP_003257928.1 KEGG: yen:YE0486 hypothetical protein YP_003257929.1 KEGG: yen:YE0485 hypothetical protein YP_003257930.1 PFAM: regulator of RNA terminal phosphate cyclase; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: pct:PC1_0403 sigma 54 interacting domain protein YP_003257931.1 PFAM: protein of unknown function UPF0027; KEGG: pct:PC1_0404 hypothetical protein YP_003257932.1 PFAM: nucleotidyltransferase, predicted; KEGG: pct:PC1_0405 hypothetical protein YP_003257933.1 KEGG: ypg:YpAngola_A1898 hypothetical protein YP_003257934.1 KEGG: eca:ECA0432 hypothetical protein YP_003257935.1 PFAM: protein of unknown function DUF1615; KEGG: eca:ECA0433 lipoprotein YP_003257936.1 PFAM: nitrate and nitrite sensing domain protein; chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0434 methyl-accepting chemotaxis protein YP_003257937.1 TIGRFAM: magnesium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; haloacid dehalogenase; KEGG: eca:ECA0435 magnesium transport ATPase YP_003257939.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_0416 methyl-accepting chemotaxis sensory transducer YP_003257940.1 TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718; KEGG: eca:ECA0437 hypothetical protein YP_003257941.1 KEGG: pct:PC1_0418 rhamnulose-1-phosphate aldolase; TIGRFAM: rhamnulose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein YP_003257942.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_003257943.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_003257944.1 activates the expression of the rhaBAD operon and rhaT gene YP_003257945.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA0442 L-rhamnose operon transcriptional activator YP_003257946.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: pct:PC1_0423 transcriptional regulator, CopG family YP_003257947.1 PFAM: plasmid stabilization system; KEGG: pct:PC1_0424 hypothetical protein YP_003257948.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_0425 ABC transporter related YP_003257949.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_0426 binding-protein-dependent transport systems inner membrane component YP_003257950.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_0427 binding-protein-dependent transport systems inner membrane component YP_003257951.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA0448 ABC transporter extracellular solute binding protein YP_003257952.1 PFAM: protein of unknown function DUF1440; KEGG: pct:PC1_0429 hypothetical protein YP_003257953.1 KEGG: pen:PSEEN0545 hypothetical protein YP_003257954.1 transports L-rhamnose and L-lyxose into the cell YP_003257955.1 PFAM: conserved hypothetical protein; KEGG: pct:PC1_0431 hypothetical protein YP_003257956.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: pct:PC1_0432 alcohol dehydrogenase zinc-binding domain protein YP_003257957.1 KEGG: pct:PC1_0433 transcriptional regulator, AraC family YP_003257958.1 KEGG: efe:EFER_1461 hypothetical protein YP_003257961.1 KEGG: conserved hypothetical protein YP_003257962.1 KEGG: eta:ETA_30000 membrane-bound sugar-binding protein YP_003257963.1 KEGG: pen:PSEEN2510 hypothetical protein YP_003257964.1 PFAM: RHS protein; KEGG: ypy:YPK_0403 YD repeat-containing protein YP_003257965.1 KEGG: hypothetical protein YP_003257968.1 PFAM: PAAR repeat-containing protein; KEGG: pct:PC1_2184 PaaR repeat-containing protein YP_003257969.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: pct:PC1_0054 type VI secretion system effector, Hcp1 family YP_003257970.1 KEGG: pct:PC1_0438 hypothetical protein YP_003257971.1 KEGG: pct:PC1_0438 hypothetical protein YP_003257972.1 KEGG: pmr:PMI2877 hypothetical protein YP_003257973.1 KEGG: eca:ECA0454 hypothetical protein YP_003257974.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: eca:ECA0457 hypothetical protein YP_003257975.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_003257976.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_003257977.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_003257978.1 PFAM: protein of unknown function DUF710; KEGG: eca:ECA0461 Z-ring-associated protein YP_003257979.1 TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: pct:PC1_0447 5-formyltetrahydrofolate cyclo-ligase YP_003257980.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_003257981.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_003257982.1 catalyzes the formation of serine from O-phosphoserine YP_003257983.1 PFAM: virulence factor, haemolysin regulator; KEGG: eca:ECA0466 hypothetical protein YP_003257984.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: amc:MADE_04053 transcriptional regulator, XRE family protein YP_003257985.1 TIGRFAM: HipA N-terminal domain protein; PFAM: HipA domain protein; KEGG: amc:MADE_04052 HipA-like protein YP_003257986.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_003257987.1 PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: pct:PC1_0454 transporter YP_003257988.1 PFAM: protein of unknown function DUF1328; KEGG: eca:ECA0470 hypothetical protein YP_003257989.1 KEGG: pct:PC1_0456 hypothetical protein YP_003257990.1 PFAM: TatD-related deoxyribonuclease; amidohydrolase 2; KEGG: eca:ECA0472 TatD family deoxyribonuclease YP_003257991.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter domain protein; nucleoside recognition domain protein; Na+ dependent nucleoside transporter; KEGG: pct:PC1_0458 nucleoside transporter YP_003257992.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: eca:ECA0474 enterobactin synthetase component D (4'-phosphopantetheinyl transferase) YP_003257993.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pct:PC1_0460 TonB-dependent receptor YP_003257994.1 KEGG: pct:PC1_0461 major facilitator superfamily MFS_1 YP_003257995.1 TIGRFAM: isochorismate synthase; PFAM: chorismate binding-like; KEGG: eca:ECA0477 isochorismate synthase YP_003257996.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_003257998.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_003257999.1 PFAM: outer membrane efflux protein; KEGG: pct:PC1_0469 outer membrane efflux protein YP_003258000.1 PFAM: Ig family protein; SMART: Dystroglycan-type cadherin domain protein; cadherin; KEGG: pct:PC1_0470 Ig family protein YP_003258001.1 PFAM: hypothetical protein; KEGG: pct:PC1_0471 tail collar domain protein YP_003258002.1 PFAM: peptidase M50; KEGG: pct:PC1_0472 peptidase M50 YP_003258003.1 KEGG: pct:PC1_0473 hypothetical protein YP_003258004.1 PFAM: hypothetical protein; KEGG: pct:PC1_0474 hypothetical protein YP_003258005.1 KEGG: eca:ECA0485 hypothetical protein YP_003258007.1 TIGRFAM: phosphoenolpyruvate phosphomutase; KEGG: eca:ECA0487 phosphoenolpyruvate phosphomutase YP_003258008.1 TIGRFAM: phosphonopyruvate decarboxylase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: eca:ECA0488 phosphonopyruvate decarboxylase YP_003258009.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: eca:ECA0489 2-hydroxy-3-oxopropionate reductase YP_003258010.1 TIGRFAM: phosphonate C-P lyase system protein PhnG; PFAM: phosphonate metabolism PhnG; KEGG: eca:ECA0490 phosphonate metabolism protein YP_003258011.1 TIGRFAM: phosphonate C-P lyase system protein PhnH; PFAM: phosphonate metabolism; KEGG: eca:ECA0491 carbon-phosphorus lyase complex subunit YP_003258012.1 PFAM: phosphonate metabolism; KEGG: eca:ECA0492 phosphonate metabolism protein YP_003258013.1 PFAM: phosphonate metabolism PhnJ; KEGG: pct:PC1_0482 phosphonate metabolism PhnJ YP_003258014.1 KEGG: eca:ECA0494 phosphonate C-P lyase system protein PhnK; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: ATPase AAA YP_003258015.1 KEGG: eca:ECA0495 phosphonate ABC transporter ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter; SMART: ATPase AAA YP_003258016.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; amidohydrolase; KEGG: eca:ECA0496 phosphonate metabolism protein YP_003258017.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: eca:ECA0497 ribose 1,5-bisphosphokinase YP_003258018.1 required for the use of phosphonates and phosphite as phosphorus sources YP_003258019.1 TIGRFAM: undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; KEGG: eca:ECA0499 capsular polysaccharide biosynthesis protein YP_003258020.1 KEGG: eca:ECA0500 capsular polysaccharide biosynthesis protein YP_003258021.1 PFAM: polysaccharide export protein; Soluble ligand binding domain; KEGG: eca:ECA0501 capsular polysaccharide export protein YP_003258022.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: eca:ECA0502 capsulatr polysaccharide biosynthesis protein YP_003258023.1 KEGG: eca:ECA0503 capsular polysaccharide bisynthesis protein YP_003258024.1 KEGG: eca:ECA0504 capsular polysaccharide bisynthesis protein YP_003258025.1 PFAM: glycosyl transferase family 2; KEGG: eca:ECA0505 capsular polysaccharide bisynthesis glycosyl transferase YP_003258026.1 PFAM: glycosyl transferase group 1; KEGG: eca:ECA0506 capsular polysaccharide bisynthesis glycosyl transferase YP_003258027.1 PFAM: glycosyl transferase group 1; protein of unknown function DUF1972; KEGG: eca:ECA0507 capsular polysaccharide bisynthesis glycosyl transferase YP_003258028.1 KEGG: eca:ECA0508 hypothetical protein YP_003258029.1 KEGG: eca:ECA0509 hypothetical protein YP_003258030.1 KEGG: eca:ECA0510 capsular polysacharide biosynthesis transferase YP_003258031.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: plu:plu1515 hypothetical protein YP_003258032.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypb:YPTS_1931 major facilitator transporter YP_003258033.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: ypb:YPTS_1935 methyltransferase type 11 YP_003258034.1 PFAM: Orn/DAP/Arg decarboxylase 2; GCN5-related N-acetyltransferase; KEGG: ypb:YPTS_1936 Orn/DAP/Arg decarboxylase 2 YP_003258035.1 KEGG: dal:Dalk_2939 plasmid pRiA4b ORF-3 family protein YP_003258036.1 KEGG: ypi:YpsIP31758_3748 hypothetical protein YP_003258037.1 KEGG: eca:ECA0518 hypothetical protein YP_003258038.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase; KEGG: ypi:YpsIP31758_3747 replicative DNA helicase YP_003258039.1 KEGG: spq:SPAB_05337 hypothetical protein YP_003258040.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: plu:plu1033 hypothetical protein YP_003258041.1 KEGG: spq:SPAB_05339 hypothetical protein YP_003258043.1 KEGG: yen:YE3512 hypothetical protein YP_003258044.1 KEGG: spq:SPAB_05341 hypothetical protein YP_003258047.1 KEGG: yen:YE3511 hypothetical protein YP_003258048.1 PFAM: Domain of unknown function DUF1845; KEGG: spq:SPAB_05346 hypothetical protein YP_003258049.1 decatenates replicating daughter chromosomes YP_003258050.1 KEGG: eca:ECA0528 hypothetical protein YP_003258051.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_003258052.1 KEGG: net:Neut_0078 hypothetical protein YP_003258053.1 PFAM: protein of unknown function DUF29; KEGG: eca:ECA0531 plasmid-related protein YP_003258054.1 KEGG: eca:ECA0532 type IV pilus protein YP_003258055.1 KEGG: eca:ECA0533 type IV pilus protein YP_003258056.1 TIGRFAM: type IVB pilus formation outer membrane protein, R64 PilN family; PFAM: Secretin domain protein; KEGG: eca:ECA0534 type IV pilus protein YP_003258057.1 KEGG: stt:t4243 pilus assembly protein YP_003258058.1 TIGRFAM: type IV pilus biogenesis protein PilP; KEGG: eca:ECA0537 type IV pilus protein YP_003258059.1 KEGG: eca:ECA0537 type IV pilus protein YP_003258060.1 PFAM: type II secretion system protein E; KEGG: eca:ECA0538 type IV pilus nucleotide-binding protein YP_003258061.1 KEGG: eca:ECA0540 type IV pilus protein YP_003258062.1 PFAM: PilS domain protein; KEGG: eca:ECA0541 type IV pilus prepilin YP_003258063.1 PFAM: lytic transglycosylase catalytic; KEGG: eca:ECA0542 type IV pilus protein YP_003258064.1 KEGG: eca:ECA0543 prepilin peptidase YP_003258065.1 PFAM: shufflon domain protein; hypothetical protein; KEGG: eca:ECA0544 type IV pilus prepilin protein YP_003258066.1 PFAM: hypothetical protein; KEGG: eca:ECA0545 alternative C-terminus for the PilV protein (fragment) YP_003258067.1 PFAM: hypothetical protein; KEGG: eca:ECA0545 alternative C-terminus for the PilV protein (fragment) YP_003258068.1 PFAM: hypothetical protein; KEGG: eca:ECA0545 alternative C-terminus for the PilV protein (fragment) YP_003258069.1 PFAM: hypothetical protein; KEGG: eca:ECA0545 alternative C-terminus for the PilV protein (fragment) YP_003258070.1 PFAM: integrase; KEGG: eca:ECA0546 shufflon-specific DNA recombinase YP_003258071.1 KEGG: spq:SPAB_05369 hypothetical protein YP_003258072.1 KEGG: spq:SPAB_05370 hypothetical protein YP_003258073.1 PFAM: lytic transglycosylase catalytic; KEGG: ypi:YpsIP31758_3720 transglycosylase SLT domain-containing protein YP_003258074.1 KEGG: yen:YE3494 hypothetical protein YP_003258075.1 KEGG: eca:ECA0559 hypothetical protein YP_003258076.1 KEGG: yen:YE3493 TraG-family protein YP_003258077.1 KEGG: yen:YE3492 inner membrane protein YP_003258078.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: pct:PC1_3239 type VI secretion system effector, Hcp1 family YP_003258079.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA2867 rhs accessory genetic element YP_003258080.1 PFAM: Domain of unknown function DUF1795; KEGG: eca:ECA2868 hypothetical protein YP_003258081.1 TIGRFAM: hypothetical protein; PFAM: PAAR repeat-containing protein; hypothetical protein; KEGG: eca:ECA2869 rhs protein YP_003258082.1 KEGG: bcj:BCAS0661B hypothetical protein YP_003258083.1 PFAM: protein of unknown function, RAQPRD; KEGG: yen:YE3490 hypothetical protein YP_003258084.1 KEGG: pmr:PMI2584 hypothetical protein YP_003258085.1 KEGG: ypi:YpsIP31758_3711 hypothetical protein YP_003258086.1 KEGG: spq:SPAB_05381 hypothetical protein YP_003258087.1 KEGG: ypi:YpsIP31758_3709 hypothetical protein YP_003258088.1 KEGG: ypi:YpsIP31758_3708 hypothetical protein YP_003258089.1 KEGG: ypi:YpsIP31758_3707 hypothetical protein YP_003258090.1 KEGG: ecq:ECED1_3575 hypothetical protein YP_003258091.1 KEGG: eca:ECA0571 hypothetical protein YP_003258092.1 KEGG: spq:SPAB_05386 hypothetical protein YP_003258093.1 KEGG: ypi:YpsIP31758_3705 hypothetical protein YP_003258094.1 KEGG: spq:SPAB_05389 hypothetical protein YP_003258095.1 KEGG: elf:LF82_p665 hypothetical protein YP_003258096.1 KEGG: hso:HS_1734 hypothetical protein YP_003258097.1 KEGG: bvi:Bcep1808_7657 hypothetical protein YP_003258098.1 PFAM: Insertion element protein; KEGG: sdy:SDY_P213 iso-IS1 ORF1 YP_003258099.1 KEGG: ecv:APECO1_381 hypothetical protein YP_003258100.1 KEGG: ecz:ECS88_1342 conserved hypothetical protein from phage origin YP_003258101.1 PFAM: RelA/SpoT domain protein; KEGG: yen:YE3463 hypothetical protein YP_003258102.1 KEGG: yen:YE3462 hypothetical protein YP_003258103.1 KEGG: amc:MADE_00113 hypothetical protein YP_003258104.1 KEGG: sew:SeSA_A1660 sefir domain protein YP_003258105.1 KEGG: vfm:VFMJ11_B0190 ATPase involved in DNA repair YP_003258106.1 PFAM: protein of unknown function DUF1525; KEGG: ypi:YpsIP31758_3702 hypothetical protein YP_003258107.1 PFAM: protein of unknown function DUF1527; KEGG: spq:SPAB_05391 hypothetical protein YP_003258108.1 KEGG: spq:SPAB_05392 hypothetical protein YP_003258109.1 KEGG: spq:SPAB_05393 hypothetical protein YP_003258110.1 KEGG: ypi:YpsIP31758_3699 hypothetical protein YP_003258111.1 KEGG: spq:SPAB_05395 hypothetical protein YP_003258112.1 KEGG: ecq:ECED1_3539 hypothetical protein YP_003258114.1 KEGG: eca:ECA0587 hypothetical protein YP_003258116.1 KEGG: eca:ECA0590 hypothetical protein YP_003258117.1 KEGG: eca:ECA0591 hypothetical protein YP_003258118.1 KEGG: eca:ECA0592 hypothetical protein YP_003258119.1 KEGG: eca:ECA0592 hypothetical protein YP_003258120.1 TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; KEGG: eca:ECA0593 DNA repair protein YP_003258121.1 KEGG: sei:SPC_4443 hypothetical protein YP_003258122.1 KEGG: eca:ECA0594 hypothetical protein YP_003258123.1 KEGG: eca:ECA0595 hypothetical protein YP_003258124.1 KEGG: eca:ECA0596 hypothetical protein YP_003258125.1 PFAM: domain of unknown function DUF1738; KEGG: eca:ECA0597 hypothetical protein YP_003258126.1 KEGG: eca:ECA0598 hypothetical protein YP_003258127.1 KEGG: eca:ECA0599 hypothetical protein YP_003258129.1 KEGG: eca:ECA0552 hypothetical protein YP_003258131.1 KEGG: ent:Ent638_1000 hypothetical protein YP_003258133.1 KEGG: eca:ECA0549 plasmid transfer protein YP_003258134.1 KEGG: spq:SPAB_05446 hypothetical protein YP_003258135.1 KEGG: ypi:YpsIP31758_3688 hypothetical protein YP_003258137.1 PFAM: protein of unknown function DUF1528; relaxase; KEGG: spq:SPAB_05448 hypothetical protein YP_003258138.1 PFAM: integrase; KEGG: yen:YE3450 phage integrase YP_003258139.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: eca:ECA0515 hypothetical protein YP_003258140.1 KEGG: glo:Glov_0280 hypothetical protein YP_003258141.1 PFAM: Domain of unknown function DUF1863; KEGG: sun:SUN_2116 hypothetical protein YP_003258142.1 KEGG: pct:PC1_0868 hypothetical protein YP_003258143.1 KEGG: pct:PC1_0869 transcriptional regulator, Nlp YP_003258144.1 KEGG: pct:PC1_0870 hypothetical protein YP_003258145.1 PFAM: integrase; KEGG: pct:PC1_0871 integrase YP_003258146.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA0615 AraC family transcription regulator YP_003258147.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA0616 hypothetical protein YP_003258148.1 KEGG: eca:ECA0617 transcriptional regulator YP_003258149.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_003258150.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_003258151.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_003258152.1 catalyzes the formation of fumarate from aspartate YP_003258153.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: eca:ECA0623 suppressor of F plamsid exlusion of phage T7 YP_003258154.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_003258155.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_003258156.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_003258157.1 catalyzes the conversion of 4-hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_003258158.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_003258159.1 PFAM: diacylglycerol kinase; KEGG: pct:PC1_0513 diacylglycerol kinase YP_003258160.1 Represses a number of genes involved in the response to DNA damage YP_003258161.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_003258162.1 PFAM: pirin; KEGG: eca:ECA0633 hypothetical protein YP_003258163.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pct:PC1_0518 LysR family transcriptional regulator YP_003258164.1 KEGG: pct:PC1_0519 glutathione transferase YP_003258165.1 PFAM: DoxX family protein; KEGG: pct:PC1_0520 DoxX family protein YP_003258166.1 KEGG: pct:PC1_0521 hypothetical protein YP_003258167.1 PFAM: protein of unknown function DUF2311, membrane; KEGG: eca:ECA0638 hypothetical protein YP_003258168.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: eca:ECA0639 hypothetical protein YP_003258169.1 KEGG: pct:PC1_0525 hypothetical protein YP_003258170.1 PFAM: SNARE associated Golgi protein; KEGG: eca:ECA0642 DedA family membrane protein YP_003258171.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_003258172.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0644 galacturonate transporter YP_003258173.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_003258174.1 catalyzes the formation of D-tagaturonate from D-altronate YP_003258175.1 PFAM: D-galactarate dehydratase/altronate hydrolase domain protein; SAF domain protein; KEGG: eca:ECA0647 altronate hydrolase YP_003258176.1 PFAM: protein of unknown function, inner membrane,YgjV; KEGG: eca:ECA0648 hypothetical protein YP_003258177.1 involved in the import of serine and threonine coupled with the import of sodium YP_003258178.1 PFAM: integral membrane protein TerC; KEGG: eca:ECA0652 hypothetical protein YP_003258179.1 PFAM: oxidoreductase domain protein; KEGG: eca:ECA0653 oxidoreductase YP_003258180.1 PFAM: methyltransferase small; KEGG: pct:PC1_0536 rRNA (guanine-N(2)-)-methyltransferase YP_003258181.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pct:PC1_0537 2,4-dienoyl-CoA reductase (NADPH) YP_003258182.1 KEGG: pct:PC1_0538 hypothetical protein YP_003258183.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_003258184.1 KEGG: eca:ECA0659 signaling membrane protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003258185.1 TIGRFAM: PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose subfamily, IIsubunit alpha; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: eca:ECA0661 PTS system, beta-glucoside-specific IIABC component YP_003258186.1 PFAM: PRD domain protein; CAT RNA-binding domain protein; KEGG: dda:Dd703_1406 transcriptional antiterminator, BglG YP_003258187.1 PFAM: porin; KEGG: eca:ECA1872 porin YP_003258188.1 PFAM: protein of unknown function DUF1593; KEGG: tau:Tola_0222 protein of unknown function DUF1593 YP_003258189.1 PFAM: sulfatase; KEGG: cps:CPS_2367 sulfatase family protein YP_003258190.1 PFAM: radical SAM protein; KEGG: pct:PC1_2436 radical SAM protein YP_003258191.1 PFAM: sulfatase; KEGG: pct:PC1_2434 sulfatase YP_003258192.1 KEGG: pmr:PMI0288 glycoporin YP_003258193.1 TIGRFAM: beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: pmr:PMI0289 beta-phosphoglucomutase YP_003258194.1 PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; KEGG: pmr:PMI0290 glycosyl hydrolase YP_003258195.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003258196.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_003258197.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA0662 6-phospho-beta-glucosidase YP_003258198.1 KEGG: pct:PC1_0544 hypothetical protein YP_003258199.1 PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; molybdopterin oxidoreductase Fe4S4 region; FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: pct:PC1_0546 molybdopterin oxidoreductase YP_003258200.1 PFAM: ThiJ/PfpI domain protein; KEGG: dze:Dd1591_2067 ThiJ/PfpI domain protein YP_003258201.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: dze:Dd1591_2066 LysR family transcriptional regulator YP_003258202.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: kpe:KPK_B0037 GntR family transcriptional regulator YP_003258203.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_003258204.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: sgl:SG2041 PTS system IIA component YP_003258205.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: sgl:SG2042 PTS system IIB component YP_003258206.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_003258207.1 KEGG: bcj:BCAM1700 acetyltransferase YP_003258208.1 PFAM: uracil-DNA glycosylase superfamily; KEGG: eca:ECA0679 G/U mismatch-specific DNA glycosylase YP_003258209.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_003258210.1 synthesizes RNA primers at the replication forks YP_003258211.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_003258212.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_003258213.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_003258214.1 oxidizes malate to oxaloacetate YP_003258215.1 KEGG: eca:ECA0686 sugar fermentation stimulation protein YP_003258216.1 PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: pct:PC1_0555 MuA-transposase/repressor protein CI DNA-binding YP_003258217.1 PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: eca:ECA0688 hypothetical protein YP_003258218.1 PFAM: polyprenyl synthetase; KEGG: pct:PC1_0557 trans-hexaprenyltranstransferase YP_003258219.1 TIGRFAM: ribosomal protein L21; PFAM: ribosomal protein L21; KEGG: pct:PC1_0558 ribosomal protein L21 YP_003258220.1 involved in the peptidyltransferase reaction during translation YP_003258221.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pct:PC1_0560 hypothetical protein YP_003258222.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_003258223.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_003258224.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_003258225.1 PFAM: protein of unknown function UPF0044; KEGG: pct:PC1_0564 hypothetical protein YP_003258226.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_003258227.1 KEGG: pct:PC1_0566 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; peptidase M41 FtsH extracellular; ATPase AAA; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA YP_003258228.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_003258229.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_003258230.1 KEGG: eca:ECA0701 hypothetical protein YP_003258231.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: eca:ECA0702 preprotein translocase subunit SecG YP_003258232.1 PFAM: protein of unknown function DUF150; KEGG: pct:PC1_0583 hypothetical protein YP_003258233.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_003258234.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_003258235.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_003258236.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_003258237.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_003258238.1 KEGG: pct:PC1_0589 polyribonucleotide nucleotidyltransferase; TIGRFAM: polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; RNA binding S1 domain protein; Exoribonuclease, phosphorolytic domain 2; K Homology, type 1, subgroup; SMART: KH domain protein YP_003258239.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_003258240.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_003258241.1 TIGRFAM: luciferase family oxidoreductase, group 1; PFAM: Luciferase-like, subgroup; KEGG: pct:PC1_0592 luciferase-like monooxygenase YP_003258242.1 KEGG: eca:ECA3326 hypothetical protein YP_003258243.1 PFAM: peptidase U32; KEGG: eca:ECA0721 hypothetical protein YP_003258244.1 PFAM: peptidase U32; KEGG: pct:PC1_0594 peptidase U32 YP_003258245.1 PFAM: sterol-binding domain protein; KEGG: eca:ECA0723 sterol transferase YP_003258246.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0724 acetyltransferase YP_003258247.1 PFAM: excinuclease ABC C subunit domain protein; KEGG: eca:ECA0725 GIY-YIG nuclease superfamily protein YP_003258248.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_003258249.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_003258250.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_003258251.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: eca:ECA0731 ferric siderophore TonB-dependent receptor YP_003258252.1 PFAM: coagulation factor 5/8 type domain protein; KEGG: pct:PC1_0610 coagulation factor 5/8 type domain protein YP_003258254.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_003258255.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_003258256.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_003258257.1 PFAM: aldo/keto reductase; KEGG: eca:ECA0736 aldo/keto reductase YP_003258258.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0737 LysR family transcriptional regulator YP_003258259.1 PFAM: protein of unknown function DUF1435; KEGG: eca:ECA0738 hypothetical protein YP_003258260.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0739 LysR family transcriptional regulator YP_003258261.1 KEGG: eca:ECA0740 alpha-acetolactate decarboxylase; TIGRFAM: alpha-acetolactate decarboxylase; PFAM: alpha-acetolactate decarboxylase YP_003258262.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_003258263.1 TIGRFAM: lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase; KEGG: pct:PC1_0621 lactaldehyde reductase YP_003258264.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_003258265.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_003258266.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_003258267.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0748 binding-protein-dependent transporter protein YP_003258268.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA0749 binding-protein-dependent transporter protein YP_003258269.1 PFAM: metallophosphoesterase; KEGG: eca:ECA0750 calcineurin-like phosphoesterase YP_003258270.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: pct:PC1_0630 ABC transporter YP_003258271.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA0752 sugar ABC transporter periplasmic protein YP_003258272.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_003258273.1 PFAM: glycoside hydrolase clan GH-D; KEGG: eca:ECA0754 alpha-galactosidase YP_003258274.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA0755 LysR family raffinose operon repressor YP_003258275.1 PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: eca:ECA0756 hypothetical protein YP_003258276.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: eca:ECA0757 hypothetical protein YP_003258277.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_003258278.1 PFAM: protein of unknown function DUF339; KEGG: pct:PC1_0638 hypothetical protein YP_003258279.1 PFAM: protein of unknown function DUF1434; KEGG: eca:ECA0760 hypothetical protein YP_003258280.1 PFAM: protein of unknown function DUF890; KEGG: eca:ECA0761 SAM-dependent methyltransferase YP_003258281.1 KEGG: eca:ECA0762 lipoprotein YP_003258282.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_003258283.1 PFAM: ABC transporter; NIL domain; SMART: AAA ATPase; KEGG: spe:Spro_1397 ABC transporter-related protein YP_003258284.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: spe:Spro_1396 binding-protein-dependent transport systems inner membrane component YP_003258285.1 PFAM: NLPA lipoprotein; KEGG: spe:Spro_1395 NlpA lipoprotein YP_003258286.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: eca:ECA0769 transporter YP_003258287.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_003258288.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_003258289.1 5'-3' single-stranded-DNA-specific exonuclease YP_003258290.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_003258291.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_003258292.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA0775 AraC family transcription regulator YP_003258293.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA0776 hypothetical protein YP_003258294.1 PFAM: integrase; KEGG: sfx:S1981 integrase YP_003258295.1 PFAM: Phage regulatory protein, Rha-like; KEGG: kpe:KPK_0786 hypothetical protein YP_003258297.1 KEGG: stt:t2949 hypothetical protein YP_003258298.1 KEGG: eca:ECA2312 hypothetical protein YP_003258299.1 PFAM: Resolvase domain; KEGG: ecs:ECs3240 resolvase YP_003258306.1 PFAM: HNH endonuclease; KEGG: ecg:E2348C_0680 predicted endonuclease YP_003258309.1 PFAM: integrase; KEGG: kpe:KPK_4425 site-specific recombinase, phage integrase family YP_003258310.1 KEGG: dze:Dd1591_4092 hypothetical protein YP_003258311.1 PFAM: protein of unknown function DUF1176; KEGG: eca:ECA0780 hypothetical protein YP_003258312.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_003258313.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: eca:ECA0783 permease YP_003258314.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: eca:ECA0784 sodium/hydrogen antiporter YP_003258315.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pct:PC1_0662 transcriptional regulator YP_003258316.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: eca:ECA0786 two component system sensor kinase YP_003258317.1 PFAM: Flp/Fap pilin component; KEGG: pct:PC1_0664 Flp/Fap pilin component YP_003258318.1 PFAM: peptidase A24A prepilin type IV; KEGG: pct:PC1_0665 peptidase A24A prepilin type IV YP_003258319.1 TIGRFAM: Flp pilus assembly protein CpaB; PFAM: SAF domain protein; KEGG: eca:ECA0788 hypothetical protein YP_003258320.1 PFAM: type II and III secretion system protein; KEGG: eca:ECA0789 hypothetical protein YP_003258321.1 TIGRFAM: pilus (Caulobacter type) biogenesis lipoprotein CpaD; PFAM: pilus biogenesis CpaD-related; KEGG: eca:ECA0790 lipoprotein YP_003258322.1 KEGG: eca:ECA0791 hypothetical protein YP_003258323.1 PFAM: type II secretion system protein E; KEGG: eca:ECA0792 type IV pilus protein YP_003258324.1 PFAM: type II secretion system F domain; KEGG: pct:PC1_0671 type II secretion system protein YP_003258325.1 PFAM: type II secretion system F domain; KEGG: eca:ECA0794 type IV pilus protein YP_003258326.1 PFAM: hypothetical protein; TPR repeat-containing protein; hypothetical protein; SMART: Tetratricopeptide repeat; KEGG: pct:PC1_0673 tetratricopeptide TPR_2 repeat protein YP_003258327.1 KEGG: pct:PC1_0674 hypothetical protein YP_003258328.1 KEGG: eca:ECA0797 hypothetical protein YP_003258329.1 KEGG: pct:PC1_0676 hypothetical protein YP_003258330.1 PFAM: Ig family protein; Two component regulator propeller; SMART: Dystroglycan-type cadherin domain protein; WD-40 repeat protein; KEGG: pct:PC1_0677 Ig family protein YP_003258331.1 KEGG: pct:PC1_0678 hypothetical protein YP_003258332.1 KEGG: pct:PC1_0679 hypothetical protein YP_003258333.1 KEGG: eca:ECA0802 hypothetical protein YP_003258334.1 KEGG: pct:PC1_0681 hypothetical protein YP_003258335.1 PFAM: Rhamnogalacturonate lyase; KEGG: eca:ECA0804 rhamnogalacturonate lyase YP_003258336.1 PFAM: transposase YhgA family protein; KEGG: eca:ECA0805 hypothetical protein YP_003258337.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_003258338.1 PFAM: protein of unknown function DUF485; KEGG: eca:ECA0807 hypothetical protein YP_003258339.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_003258340.1 KEGG: eca:ECA0809 global regulatory protein YP_003258341.1 PFAM: hypothetical protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRD domain protein; KEGG: ent:Ent638_0433 transcriptional antiterminator, BglG YP_003258342.1 PFAM: protein of unknown function DUF1341; KEGG: cko:CKO_03584 hypothetical protein YP_003258343.1 TIGRFAM: pyridoxal phosphate-dependent enzyme; PFAM: pyridoxal phosphate-dependent transferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ent:Ent638_0430 pyridoxal phosphate-dependent enzyme YP_003258344.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_003258345.1 KEGG: ent:Ent638_0428 inner membrane protein YP_003258346.1 KEGG: cko:CKO_03588 hypothetical protein YP_003258347.1 KEGG: esa:ESA_00249 hypothetical protein YP_003258348.1 KEGG: cko:CKO_03590 hypothetical protein YP_003258349.1 PFAM: PRD domain protein; KEGG: cko:CKO_03591 hypothetical protein YP_003258350.1 KEGG: eca:ECA0815 hypothetical protein YP_003258351.1 KEGG: pct:PC1_0691 oligogalacturonide transporter YP_003258352.1 KEGG: pct:PC1_0692 hypothetical protein YP_003258353.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: pct:PC1_0693 mannitol dehydrogenase domain protein YP_003258354.1 KEGG: pct:PC1_0694 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_003258355.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: pct:PC1_0695 ErfK/YbiS/YcfS/YnhG family protein YP_003258356.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: eca:ECA0822 carbon-nitrogen hydrolase YP_003258357.1 PFAM: cytochrome B561; KEGG: eca:ECA0823 cytochrome b561 YP_003258358.1 TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate-flavodoxin oxidoreductase, EKR domain; KEGG: pct:PC1_0698 pyruvate ferredoxin/flavodoxin oxidoreductase YP_003258359.1 KEGG: eca:ECA0825 hypothetical protein YP_003258360.1 PFAM: glycoside hydrolase family 43; KEGG: pct:PC1_0700 glycoside hydrolase family 43 YP_003258361.1 TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_0701 sugar (glycoside-pentoside-hexuronide) transporter YP_003258362.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_0703 GCN5-related N-acetyltransferase YP_003258363.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA0827 amino acid efflux protein YP_003258365.1 PFAM: protein of unknown function DUF1493; KEGG: sec:SC2504 cytoplasmic protein YP_003258366.1 KEGG: pct:PC1_3264 hypothetical protein YP_003258367.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: eca:ECA3452 cell filamentation protein YP_003258368.1 PFAM: plasmid stabilization system; KEGG: eca:ECA2758 hypothetical protein YP_003258369.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: dze:Dd1591_2452 transcriptional regulator, CopG family YP_003258370.1 KEGG: cko:CKO_00978 hypothetical protein YP_003258371.1 PFAM: major facilitator superfamily MFS_1; KEGG: cko:CKO_00976 hypothetical protein YP_003258372.1 PFAM: IucA/IucC family protein; KEGG: ses:SARI_02152 hypothetical protein YP_003258373.1 PFAM: Siderophore biosynthesis protein, conserved region; KEGG: cko:CKO_00972 hypothetical protein YP_003258374.1 PFAM: IucA/IucC family protein; KEGG: cko:CKO_00971 hypothetical protein YP_003258375.1 KEGG: cko:CKO_00970 hypothetical protein YP_003258376.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cko:CKO_00969 hypothetical protein YP_003258377.1 KEGG: pmr:PMI2492 hypothetical protein YP_003258378.1 PFAM: Domain of unknown function DUF1814; KEGG: plu:plu0453 hypothetical protein YP_003258379.1 PFAM: protein of unknown function DUF172; KEGG: pct:PC1_0709 hypothetical protein YP_003258380.1 KEGG: bmj:BMULJ_02360 predicted ATPase YP_003258381.1 KEGG: rfr:Rfer_1068 hypothetical protein YP_003258382.1 PFAM: integrase; KEGG: pct:PC1_0723 integrase YP_003258383.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_003258384.1 PFAM: cyclase/dehydrase; polyketide cyclase/dehydrase; KEGG: pct:PC1_0725 cyclase/dehydrase YP_003258385.1 PFAM: protein of unknown function UPF0125; KEGG: eca:ECA0838 hypothetical protein YP_003258386.1 PFAM: SmpA/OmlA domain protein; KEGG: pct:PC1_0727 SmpA/OmlA domain protein YP_003258387.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: pct:PC1_0728 DNA repair protein RecN YP_003258388.1 catalyzes the phosphorylation of NAD to NADP YP_003258389.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_003258390.1 TIGRFAM: Mn2+/Fe2+ transporter NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: pct:PC1_0731 Mn2+/Fe2+ transporter NRAMP family YP_003258392.1 KEGG: bra:BRADO6232 hypothetical protein YP_003258393.1 KEGG: sde:Sde_2336 hypothetical protein YP_003258394.1 TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: pct:PC1_0732 4-oxalocrotonate tautomerase family enzyme YP_003258395.1 PFAM: NUDIX hydrolase; KEGG: pct:PC1_0735 NUDIX hydrolase YP_003258396.1 PFAM: extracellular solute-binding protein family 1; KEGG: pct:PC1_0736 extracellular solute-binding protein family 1 YP_003258397.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_0737 binding-protein-dependent transport systems inner membrane component YP_003258398.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_0738 binding-protein-dependent transport systems inner membrane component YP_003258399.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_0739 ABC transporter YP_003258400.1 PFAM: glycosyl hydrolase 53 domain protein; ricin B lectin; KEGG: pct:PC1_0740 arabinogalactan endo-1,4-beta-galactosidase YP_003258401.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: pct:PC1_0741 LacI family transcriptional regulator YP_003258402.1 PFAM: PRD domain protein; CAT RNA-binding domain protein; KEGG: pct:PC1_0742 transcriptional antiterminator, BglG YP_003258403.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA0859 beta-glucosidase YP_003258404.1 TIGRFAM: PTS system, beta-glucoside-specific IIABC subunit; PTS system, glucose subfamily, IIsubunit alpha; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: eca:ECA0860 PTS system, IIABC component YP_003258405.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_003258406.1 KEGG: eca:ECA0862 transaldolase A; TIGRFAM: transaldolase; PFAM: transaldolase YP_003258407.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_003258408.1 PFAM: PTS system glucitol/sorbitol-specific IIA component; KEGG: pct:PC1_0748 PTS system glucitol/sorbitol-specific IIA component YP_003258409.1 transports degraded pectin products into the bacterial cell YP_003258410.1 PFAM: Sorbitol phosphotransferase protein II domain protein; type III effector Hrp-dependent outers; KEGG: pct:PC1_0750 protein-N(pi)-phosphohistidine--sugar phosphotransferase YP_003258411.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_003258412.1 TIGRFAM: triosephosphate isomerase; PFAM: triosephosphate isomerase; KEGG: pct:PC1_0752 triosephosphate isomerase YP_003258413.1 PFAM: sugar-binding domain protein; KEGG: pct:PC1_0753 DeoR family transcriptional regulator YP_003258414.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_003258415.1 tryptophan transporter of high affinity YP_003258416.1 PFAM: protein of unknown function DUF188; KEGG: eca:ECA0873 hypothetical protein YP_003258417.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_003258418.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_0758 GCN5-related N-acetyltransferase YP_003258419.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: mei:Msip34_0417 RNA polymerase, sigma-24 subunit, ECF subfamily YP_003258420.1 PFAM: FecR protein; KEGG: mei:Msip34_0416 anti-FecI sigma factor, FecR YP_003258421.1 PFAM: TonB-dependent receptor plug; Secretin/TonB short domain; KEGG: eca:ECA0878 hypothetical protein YP_003258422.1 PFAM: peptidase M16 domain protein; KEGG: eca:ECA0879 zinc protease YP_003258423.1 PFAM: ABC transporter; ABC transporter related; SbmABacA family protein; SMART: ATPase AAA; KEGG: pct:PC1_0762 ABC transporter YP_003258424.1 PFAM: protein of unknown function DUF1131; KEGG: pct:PC1_0763 hypothetical protein YP_003258425.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: eca:ECA0882 hypothetical protein YP_003258426.1 TIGRFAM: sulfate ABC transporter periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: pct:PC1_0765 sulfate ABC transporter periplasmic sulfate-binding protein YP_003258427.1 TIGRFAM: sulfate ABC transporter inner membrane protein CysT; sulfate ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_0766 sulfate ABC transporter inner membrane protein CysT YP_003258428.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_003258429.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_003258430.1 PFAM: ABC transporter; protein of unknown function DUF214; SMART: ATPase AAA; KEGG: pct:PC1_0769 ABC transporter YP_003258431.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; hypothetical protein family protein; KEGG: eca:ECA0888 macrolide-specific efflux protein maca precursor YP_003258432.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pct:PC1_0771 transcriptional regulator YP_003258433.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA0890 two-component system sensor kinase YP_003258434.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_003258435.1 phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transporter YP_003258436.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: pct:PC1_0775 phosphotransferase system, phosphocarrier protein HPr YP_003258437.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_003258438.1 role in sulfur assimilation YP_003258439.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_003258440.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_003258441.1 PFAM: protein of unknown function DUF526; KEGG: pct:PC1_0780 hypothetical protein YP_003258442.1 DHBP synthase; functions during riboflavin biosynthesis YP_003258443.1 with TehA confers resistance to tellurite YP_003258444.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_003258445.1 detoxifies nitric oxide using NADH YP_003258446.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_003258447.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, subunit alpha; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: pct:PC1_0786 hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta YP_003258448.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0905 LysR family transcriptional regulator YP_003258449.1 PFAM: transmembrane pair domain protein; KEGG: pct:PC1_0789 transmembrane pair domain protein YP_003258450.1 KEGG: eca:ECA0907 DNA-3-methyladenine glycosylase; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein YP_003258451.1 KEGG: eca:ECA0908 ADA regulatory protein (methylated-DNA--protein-cysteine methyltransferase); TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain protein; methylguanine DNA methyltransferase ribonuclease domain protein; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain YP_003258452.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: pct:PC1_0794 2OG-Fe(II) oxygenase YP_003258453.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: eca:ECA0910 flavoprotein subunit of a reductase YP_003258454.1 PFAM: FMN-binding domain protein; KEGG: pct:PC1_0796 FMN-binding domain protein YP_003258455.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA0912 hypothetical protein YP_003258456.1 TIGRFAM: cytochrome C nitrite reductase, NrfD subunit; PFAM: polysulphide reductase NrfD; KEGG: eca:ECA0913 component of polysulfide reductase YP_003258457.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA0914 component of polysulfide reductase YP_003258458.1 PFAM: alpha/beta hydrolase; KEGG: pct:PC1_0800 alpha/beta hydrolase YP_003258459.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0916 LysR family transcriptional regulator YP_003258460.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0917 starvation sensing mandelate racemase / muconate lactonizing enzyme YP_003258461.1 PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; KEGG: pct:PC1_0803 alcohol dehydrogenase GroES YP_003258462.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA0919 transporter YP_003258463.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: eca:ECA0920 carbohydrate oxidoreductase YP_003258464.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA0921 GntR family transcriptional regulator YP_003258465.1 KEGG: eca:ECA0924 hypothetical protein YP_003258466.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA0930 permease YP_003258467.1 KEGG: eca:ECA0931 avirulence protein YP_003258468.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: eca:ECA0932 permease YP_003258469.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: pct:PC1_0816 LuxR family transcriptional regulator YP_003258470.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: bbt:BBta_0488 inositol 2-dehydrogenase YP_003258471.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: bja:blr2556 thiosulfate sulfurtransferase YP_003258472.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: bxe:Bxe_A2431 polar amino acid ABC transporter ATPase YP_003258473.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pfs:PFLU2235 ABC transporter, membrane protein YP_003258474.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ppg:PputGB1_3165 polar amino acid ABC transporter inner membrane protein YP_003258475.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: avn:Avin_21410 ABC transporter substrate binding protein, family 3 YP_003258476.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: mes:Meso_0408 IclR family transcriptional regulator YP_003258477.1 KEGG: reu:Reut_B3581 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein YP_003258478.1 PFAM: capsule synthesis protein, CapA; KEGG: bph:Bphy_3228 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)-like protein YP_003258479.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: eca:ECA0935 ferric-rhodotorulic acid outer membrane transporter YP_003258480.1 KEGG: pct:PC1_0821 hypothetical protein YP_003258481.1 PFAM: fimbrial protein; KEGG: eca:ECA0939 fimbrial protein YP_003258482.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: pct:PC1_0824 pili assembly chaperone, N-terminal YP_003258483.1 KEGG: eca:ECA0942 outer membrane usher protein YP_003258484.1 KEGG: eca:ECA0944 hypothetical protein YP_003258485.1 KEGG: pct:PC1_0828 hypothetical protein YP_003258486.1 PFAM: conserved hypothetical protein; KEGG: kpn:KPN_02004 hypothetical protein YP_003258487.1 KEGG: eca:ECA0948 hypothetical protein YP_003258488.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA0949 hypothetical protein YP_003258489.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA0954 acetyltransferase YP_003258490.1 KEGG: dda:Dd703_3431 hypothetical protein YP_003258491.1 TIGRFAM: type VI hypothetical protein, VC_A0107 family; PFAM: conserved hypothetical protein; KEGG: eca:ECA3445 hypothetical protein YP_003258492.1 TIGRFAM: type VI hypothetical protein, EvpB/VC_A0108 family; PFAM: protein of unknown function DUF877; KEGG: eca:ECA3444 hypothetical protein YP_003258493.1 TIGRFAM: type VI secretion system lysozyme-related protein; PFAM: GPW/gp25 family protein; KEGG: eca:ECA3443 hypothetical protein YP_003258494.1 TIGRFAM: type VI hypothetical protein, VC_A0110 family; PFAM: protein of unknown function DUF879; KEGG: pct:PC1_3252 type VI hypothetical protein, VC_A0110 family YP_003258495.1 TIGRFAM: type VI hypothetical protein, VC_A0111 family; PFAM: protein of unknown function DUF1305; KEGG: eca:ECA3441 hypothetical protein YP_003258496.1 TIGRFAM: type VI secretion system FHA domain protein; PFAM: Forkhead-associated protein; KEGG: pct:PC1_3250 FHA domain containing protein YP_003258497.1 TIGRFAM: type VI secretion lipoprotein, VC_A0113 family; KEGG: pct:PC1_3249 type VI secretion lipoprotein, VC_A0113 family YP_003258498.1 TIGRFAM: type VI hypothetical protein, VC_A0114 family; PFAM: protein of unknown function DUF876; KEGG: eca:ECA3438 hypothetical protein YP_003258499.1 TIGRFAM: type IV / VI secretion system protein, DotU family; PFAM: type IV / VI secretion system, DotU; KEGG: pct:PC1_3247 type IV / VI secretion system protein, DotU family YP_003258500.1 KEGG: pct:PC1_3246 type VI secretion ATPase, ClpV1 family; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: ATPase AAA-2 domain protein; ATPase AAA; Clp ATPase-like; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA YP_003258501.1 PFAM: sigma-54 factor interaction domain-containing protein; SMART: ATPase AAA; KEGG: pct:PC1_3245 sigma 54 interacting domain protein YP_003258502.1 TIGRFAM: type VI secretion-associated protein, VC_A0118 family; KEGG: pct:PC1_3244 type VI secretion-associated protein, VC_A0118 family YP_003258503.1 TIGRFAM: type VI secretion-associated protein, VC_A0119 family; PFAM: ImpA domain protein; KEGG: eca:ECA3433 hypothetical protein YP_003258504.1 TIGRFAM: type VI hypothetical protein IcmF; PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: pct:PC1_3242 type VI hypothetical protein IcmF YP_003258505.1 PFAM: ImpA domain protein; KEGG: pct:PC1_3241 ImpA domain protein YP_003258506.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: pct:PC1_3240 Sel1 domain protein repeat-containing protein YP_003258507.1 KEGG: dze:Dd1591_2810 hypothetical protein YP_003258508.1 KEGG: cvi:CV_1430 hypothetical protein YP_003258512.1 KEGG: sea:SeAg_B3023 cytoplasmic protein YP_003258518.1 PFAM: ankyrin; SMART: ankyrin; KEGG: wpi:WPa_1379 ankyrin repeat domain protein YP_003258519.1 KEGG: ccv:CCV52592_0510 hypothetical protein YP_003258520.1 KEGG: esa:ESA_03895 hypothetical protein YP_003258521.1 KEGG: pct:PC1_3232 hypothetical protein YP_003258522.1 KEGG: hypothetical protein YP_003258523.1 KEGG: eca:ECA3420 hypothetical protein YP_003258524.1 PFAM: Pyoverdine biosynthesis protein; KEGG: eca:ECA3381 pyoverdine biosynthesis protein YP_003258525.1 PFAM: taurine catabolism dioxygenase TauD/TfdA; KEGG: eca:ECA3380 pyoverdine biosynthesis protein YP_003258526.1 TIGRFAM: glycosyltransferase, MGT family; PFAM: glycosyl transferase family 28; UDP-glucuronosyl/UDP-glucosyltransferase; protein of unknown function DUF1205; KEGG: eca:ECA3379 glycosyltransferase YP_003258527.1 cofactor involved in the reduction of disulfides YP_003258528.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3376 LysR family transcriptional regulator YP_003258529.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3375 transporter YP_003258530.1 KEGG: eca:ECA3374 signaling membrane protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003258531.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_003258532.1 PFAM: cyclase/dehydrase; KEGG: pct:PC1_3216 cyclase/dehydrase YP_003258533.1 KEGG: eca:ECA3371 hypothetical protein YP_003258534.1 PFAM: damage inducible protein CinA; KEGG: eca:ECA3370 competence damage-inducible protein A YP_003258535.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_003258536.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_003258537.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003258538.1 affects carbohydrate metabolism; has regulatory role in many processes YP_003258539.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_003258540.1 KEGG: eca:ECA3364 hypothetical protein YP_003258541.1 involved in the first step of glutathione biosynthesis YP_003258542.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_003258543.1 PFAM: cytochrome C assembly protein; KEGG: pct:PC1_3205 cytochrome C assembly protein YP_003258544.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_003258545.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_003258546.1 Essential for efficient processing of 16S rRNA YP_003258547.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_003258548.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_003258549.1 KEGG: eca:ECA3355 hypothetical protein YP_003258550.1 KEGG: eca:ECA3354 hypothetical protein YP_003258551.1 unknown function; when overproduced it confers drug-resistance YP_003258552.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_003258553.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_003258554.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_003258555.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: eca:ECA3349 sigma(54) modulation protein YP_003258556.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_003258557.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_003258558.1 PFAM: protein of unknown function DUF152; KEGG: pct:PC1_3142 hypothetical protein YP_003258559.1 KEGG: eca:ECA3345 protein disaggregation chaperone; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; ATPase AAA; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA YP_003258560.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: pct:PC1_3140 endonuclease/exonuclease/phosphatase YP_003258561.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_003258562.1 KEGG: eca:ECA3342 hydroxyacylglutathione hydrolase; TIGRFAM: hydroxyacylglutathione hydrolase; PFAM: beta-lactamase domain protein YP_003258563.1 PFAM: methyltransferase type 11; KEGG: eca:ECA3341 hypothetical protein YP_003258564.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_003258565.1 3'-5' exonuclease of DNA polymerase III YP_003258566.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_003258567.1 Catalyzes the rate-limiting step in dNTP synthesis YP_003258568.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_003258569.1 TIGRFAM: glutaredoxin; PFAM: glutaredoxin; KEGG: eca:ECA3335 glutaredoxin YP_003258571.1 KEGG: eca:ECA3332 hypothetical protein YP_003258572.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3331 ABC transporter permease YP_003258573.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: pct:PC1_3126 ABC transporter YP_003258574.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3329 acetyltransferase YP_003258575.1 KEGG: pct:PC1_3124 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_003258576.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_003258577.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3325 ABC transporter ATP-binding protein YP_003258578.1 PFAM: ABC transporter; KEGG: eca:ECA3324 ABC transporter integral membrane protein YP_003258579.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_003258580.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_003258581.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_003258582.1 KEGG: eca:ECA3320 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK YP_003258583.1 polymerase that creates the 3' poly(A) tail found in some mRNA's YP_003258584.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_003258585.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: eca:ECA3317 DnaK transcriptional regulator DksA YP_003258586.1 Regulatory factor involved in maltose metabolism YP_003258587.1 TIGRFAM: 2'-5' RNA ligase; PFAM: phosphoesterase HXTX; KEGG: eca:ECA3315 2'-5' RNA ligase YP_003258588.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_003258589.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_003258590.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_003258591.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_003258592.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_003258593.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA3309 hypothetical protein YP_003258594.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: eca:ECA3308 aminotransferase YP_003258595.1 PFAM: glutathione S-transferase domain; KEGG: pct:PC1_3104 glutathione S-transferase YP_003258596.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_003258597.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: eca:ECA3306 hypothetical protein YP_003258598.1 KEGG: eca:ECA3305 lipoprotein YP_003258599.1 solute binding component of the vitamin B12 transport system BtuCDF YP_003258600.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_003258601.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_003258602.1 protease Do; required at high temperature; degrades damaged proteins YP_003258603.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_003258604.1 TIGRFAM: sulfate ABC transporter periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA3299 sulfate-binding protein YP_003258605.1 TIGRFAM: sulfate ABC transporter inner membrane protein CysT; sulfate ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_3093 sulfate ABC transporter inner membrane protein CysT YP_003258606.1 TIGRFAM: sulfate ABC transporter inner membrane protein CysW; sulfate ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3297 sulfate ABC transporter permease YP_003258607.1 KEGG: eca:ECA3296 sulfate ABC transporter ATP-binding protein; TIGRFAM: sulfate ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA YP_003258608.1 PFAM: DoxX family protein; KEGG: eca:ECA3295 hypothetical protein YP_003258609.1 PFAM: regulatory protein TetR; KEGG: eca:ECA3294 TetR family transcriptional regulator YP_003258610.1 PFAM: aldo/keto reductase; KEGG: eca:ECA3293 oxidoreductase YP_003258611.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: eca:ECA3292 oxidoreductase YP_003258612.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_003258613.1 PFAM: esterase; KEGG: eca:ECA3290 hypothetical protein YP_003258614.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_003258615.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_003258616.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_003258617.1 PFAM: methyltransferase small; KEGG: eca:ECA3286 hypothetical protein YP_003258618.1 catalyzes the formation of oxaloacetate from L-aspartate YP_003258619.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_003258620.1 PFAM: anti sigma-E protein RseA family protein; anti sigma-E protein RseA domain protein; KEGG: eca:ECA3283 anti-RNA polymerase sigma factor SigE YP_003258621.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_003258622.1 involved in the reduction of the SoxR iron-sulfur cluster YP_003258623.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_003258624.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_003258625.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_003258626.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_003258627.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_003258628.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_003258629.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_003258630.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA3273 ferredoxin YP_003258631.1 in Escherichia coli this protein is involved in flagellar function YP_003258632.1 KEGG: eca:ECA3270 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein YP_003258633.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: hypothetical protein; KEGG: eca:ECA3269 HlyD family hypothetical protein YP_003258634.1 KEGG: eca:ECA3268 toxin secretion ATP-binding protein; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: ATPase AAA YP_003258635.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: eca:ECA3267 agglutination protein YP_003258636.1 TIGRFAM: type 1 secretion C-terminal target domain; PFAM: Hemolysin-type calcium-binding region; KEGG: eca:ECA3266 hemagglutinin/hemolysin-related protein YP_003258637.1 KEGG: pct:PC1_3059 hypothetical protein YP_003258638.1 KEGG: eca:ECA3264 signaling membrane protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; SMART: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein YP_003258639.1 PFAM: transglutaminase family protein cysteine peptidase BTLCP; KEGG: pct:PC1_3057 transglutaminase family protein cysteine peptidase BTLCP YP_003258640.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_003258641.1 TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: eca:ECA3261 hypothetical protein YP_003258642.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: eca:ECA3260 tRNA-specific adenosine deaminase YP_003258643.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_003258644.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_003258645.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pct:PC1_3051 histidine kinase YP_003258646.1 KEGG: eca:ECA3256 hypothetical protein YP_003258647.1 PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; ATPase AAA; KEGG: pct:PC1_3049 two component, sigma54 specific, transcriptional regulator, Fis family YP_003258648.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_003258649.1 PFAM: pectinesterase; KEGG: eca:ECA3253 pectinesterase A YP_003258650.1 KEGG: pct:PC1_3046 pectin acetylesterase YP_003258651.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_003258652.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_003258653.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_003258654.1 PFAM: protein of unknown function DUF1007; KEGG: eca:ECA3248 hypothetical protein YP_003258655.1 PFAM: high-affinity nickel-transporter; KEGG: eca:ECA3247 hypothetical protein YP_003258656.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3246 periplasmic substrate-binding transporter YP_003258657.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3245 methyl-accepting chemotaxis protein YP_003258658.1 KEGG: eca:ECA3244 hypothetical protein YP_003258659.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3243 ferric-enterobactin ABC transporter ATP-binding protein YP_003258660.1 PFAM: transporter permease; KEGG: pct:PC1_3036 transporter permease YP_003258661.1 PFAM: periplasmic binding protein; KEGG: pct:PC1_3035 periplasmic binding protein YP_003258662.1 PFAM: inositol monophosphatase; KEGG: eca:ECA3240 inositol monophosphatase YP_003258663.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: eca:ECA3239 RNA methyltransferase YP_003258664.1 regulates the expression of the iscRSUA operon YP_003258665.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_003258666.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: pct:PC1_3030 FeS cluster assembly scaffold IscU YP_003258667.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_003258668.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_003258669.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_003258670.1 TIGRFAM: ferredoxin 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: pct:PC1_3026 ferredoxin 2Fe-2S type, ISC system YP_003258671.1 TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528; KEGG: pct:PC1_3025 FeS assembly protein IscX YP_003258672.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_003258673.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_003258674.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_003258675.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_003258676.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_003258677.1 KEGG: eca:ECA3222 hypothetical protein; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: Tetratricopeptide TPR_2 repeat protein; hypothetical protein; SMART: Tetratricopeptide repeat YP_003258678.1 SMART: hypothetical protein; KEGG: eca:ECA3221 hypothetical protein YP_003258679.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_003258680.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_003258681.1 PFAM: protein of unknown function DUF2133; KEGG: eca:ECA3218 hypothetical protein YP_003258682.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_003258683.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_003258684.1 PFAM: hypothetical protein; KEGG: eca:ECA3215 transporter YP_003258685.1 PFAM: protein of unknown function DUF1407; KEGG: pct:PC1_3008 hypothetical protein YP_003258686.1 KEGG: pct:PC1_3007 hypothetical protein YP_003258687.1 PFAM: peptidase M4 thermolysin; peptidase M4 thermolysin; KEGG: eca:ECA3211 extracellular metalloprotease YP_003258688.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_003258689.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_003258690.1 PFAM: RIO-like kinase; SMART: protein of unknown function RIO1; KEGG: eca:ECA3207 hypothetical protein YP_003258691.1 PFAM: aldo/keto reductase; KEGG: xcv:XCV4212 oxidoreductase YP_003258692.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: dze:Dd1591_0122 alcohol dehydrogenase zinc-binding domain protein YP_003258693.1 PFAM: regulatory protein TetR; KEGG: rlt:Rleg2_2308 TetR family transcriptional regulator YP_003258694.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: pct:PC1_2996 Sel1 domain protein repeat-containing protein YP_003258695.1 PFAM: YCII-related; KEGG: pct:PC1_2992 YCII-related protein YP_003258696.1 PFAM: choloylglycine hydrolase; KEGG: eca:ECA3205 exported choloylglycine hydrolase YP_003258697.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pst:PSPTO_1003 acetyltransferase YP_003258698.1 PFAM: protein of unknown function DUF1486; KEGG: pct:PC1_2990 hypothetical protein YP_003258699.1 KEGG: pct:PC1_2989 hypothetical protein YP_003258700.1 PFAM: protein of unknown function DUF81; KEGG: pct:PC1_2986 hypothetical protein YP_003258702.1 KEGG: pct:PC1_2985 hypothetical protein YP_003258703.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: pct:PC1_2984 alcohol dehydrogenase zinc-binding domain protein YP_003258704.1 KEGG: eca:ECA3199 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003258706.1 KEGG: dze:Dd1591_2791 hypothetical protein YP_003258707.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: eca:ECA3198 zinc-binding dehydrogenase YP_003258708.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_003258709.1 TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: msu:MS0334 LeuD protein YP_003258710.1 PFAM: fumarylacetoacetate hydrolase; KEGG: eca:ECA2575 fumarylacetoacetate hydrolase YP_003258711.1 PFAM: citrate carrier protein; KEGG: spe:Spro_2099 citrate carrier protein YP_003258712.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: msu:MS0336 LysR protein YP_003258713.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_003258714.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_003258715.1 PFAM: phosphate-starvation-inducible E; KEGG: eca:ECA3195 phosphate-starvation-inducible protein PsiE YP_003258716.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_003258717.1 PFAM: peptidase U32; KEGG: pct:PC1_2976 peptidase U32 YP_003258718.1 KEGG: eca:ECA3192 hypothetical protein YP_003258719.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_2974 GCN5-related N-acetyltransferase YP_003258720.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_003258721.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA3188 signal transduction histidine-protein kinase BaeS YP_003258722.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3187 multidrug efflux system protein MdtE YP_003258723.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_003258724.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_003258725.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_003258726.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter domain protein; nucleoside recognition domain protein; Na+ dependent nucleoside transporter; KEGG: eca:ECA3183 nucleoside permease YP_003258727.1 PFAM: aldo/keto reductase; KEGG: eca:ECA3182 oxidoreductase YP_003258728.1 component of the membrane-bound D-lactate oxidase FAD-binding, NADH independent YP_003258729.1 PFAM: glycoside hydrolase family 42 domain protein; beta-galactosidase trimerisation domain protein; beta-galactosidase domain protein; KEGG: eca:ECA3179 beta-galactosidase YP_003258730.1 PFAM: glycosyl hydrolase 53 domain protein; KEGG: eca:ECA3178 arabinogalactan endo-1,4-beta-galactosidase YP_003258731.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3177 maltose/maltodextrin transport permease protein YP_003258732.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3176 maltose transporter permease protein YP_003258733.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA3175 maltose-binding periplasmic protein YP_003258734.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: pct:PC1_2957 ABC transporter YP_003258735.1 porin involved in the transport of maltose and maltodextrins YP_003258736.1 controls transcription of galETKM YP_003258737.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_003258738.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_003258739.1 TIGRFAM: magnesium transporter; PFAM: MgtE intracellular region; CBS domain containing protein; MgtE integral membrane region; KEGG: eca:ECA3169 magnesium transporter YP_003258740.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: pct:PC1_2950 MarR family transcriptional regulator YP_003258741.1 TIGRFAM: peroxiredoxin, Ohr subfamily; PFAM: OsmC family protein; KEGG: eca:ECA3167 organic hydroperoxide resistance protein YP_003258742.1 KEGG: pct:PC1_2948 hypothetical protein YP_003258743.1 KEGG: pct:PC1_2947 hypothetical protein YP_003258744.1 PFAM: Ppx/GppA phosphatase; KEGG: eca:ECA3165 exopolyphosphatase YP_003258745.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_003258746.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3163 phosphate ABC transporter permease protein YP_003258747.1 TIGRFAM: phosphate ABC transporter inner membrane protein PstA; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_2943 phosphate ABC transporter inner membrane protein PstA YP_003258748.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_003258749.1 KEGG: rpa:RPA2267 hypothetical protein YP_003258750.1 PFAM: hypothetical protein; KEGG: eca:ECA3160 transcriptional regulator YP_003258751.1 TIGRFAM: serine transporter; PFAM: Spore germination protein; Amino acid transporter transmembrane; KEGG: pct:PC1_2939 serine transporter YP_003258752.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_003258753.1 KEGG: pct:PC1_2937 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_003258754.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_003258755.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: pct:PC1_2935 peptidyl-prolyl cis-trans isomerase cyclophilin type YP_003258756.1 PFAM: DoxX family protein; KEGG: pct:PC1_2934 DoxX family protein YP_003258757.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_003258758.1 KEGG: eca:ECA3150 hypothetical protein YP_003258759.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_003258760.1 KEGG: pct:PC1_2930 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003258761.1 KEGG: pct:PC1_2929 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase YP_003258762.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_003258763.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_003258764.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_003258765.1 PFAM: polysaccharide deacetylase; KEGG: eca:ECA3143 hypothetical protein YP_003258766.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_003258767.1 PFAM: small multidrug resistance protein; KEGG: eca:ECA3141 hypothetical protein YP_003258768.1 KEGG: eca:ECA3140 hypothetical protein YP_003258769.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: eca:ECA3139 iron(III)-transport ATP-binding protein YP_003258770.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3138 iron(III)-transporter permease protein YP_003258771.1 PFAM: extracellular solute-binding protein family 1; KEGG: pct:PC1_2919 extracellular solute-binding protein family 1 YP_003258772.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3134 LysR family transcriptional regulator YP_003258773.1 KEGG: eca:ECA3132 lipoprotein YP_003258774.1 KEGG: eca:ECA3130 poly(glycerophosphate chain) D-alanine transfer protein YP_003258775.1 KEGG: pct:PC1_2912 hypothetical protein YP_003258776.1 PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: eca:ECA3129 peptidoglycan biosynthesis protein YP_003258777.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA3128 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_003258778.1 KEGG: pct:PC1_2909 acyl carrier protein YP_003258779.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_003258780.1 PFAM: Domain of unknown function DUF1852; KEGG: eca:ECA3125 hypothetical protein YP_003258781.1 PFAM: NUDIX hydrolase; KEGG: pen:PSEEN1183 hydrolase, MutT/NUDIX family protein YP_003258782.1 PFAM: regulatory protein TetR; KEGG: pct:PC1_2715 TetR family transcriptional regulator YP_003258783.1 PFAM: transposase IS3/IS911 family protein; KEGG: har:HEAR2248 transposase YP_003258784.1 KEGG: csa:Csal_2377 hypothetical protein YP_003258785.1 PFAM: integrase; KEGG: pct:PC1_2870 integrase YP_003258786.1 KEGG: pct:PC1_2892 hypothetical protein YP_003258787.1 KEGG: eca:ECA2852 hypothetical protein YP_003258788.1 PFAM: protein of unknown function DUF1219; KEGG: eca:ECA2853 hypothetical protein YP_003258789.1 PFAM: YagBYeeUYfjZ family protein; KEGG: eca:ECA2854 hypothetical protein YP_003258790.1 TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; KEGG: eca:ECA2855 hypothetical protein YP_003258791.1 KEGG: pct:PC1_2887 CP4-57 prophage; inner membrane protein YP_003258792.1 KEGG: pct:PC1_2886 hypothetical protein YP_003258793.1 KEGG: pct:PC1_2885 hypothetical protein YP_003258794.1 PFAM: regulatory protein DeoR; KEGG: pct:PC1_2884 regulatory protein DeoR YP_003258795.1 PFAM: GTP-binding protein HSR1-related; KEGG: pct:PC1_2882 GTP-binding protein HSR1-related YP_003258796.1 KEGG: hypothetical protein YP_003258797.1 PFAM: prophage CP4-57 regulator; KEGG: pct:PC1_2878 phage transcriptional regulator, AlpA YP_003258798.1 KEGG: ypi:YpsIP31758_0767 hypothetical protein YP_003258799.1 KEGG: eca:ECA2864 hypothetical protein YP_003258800.1 KEGG: ypi:YpsIP31758_0768 hypothetical protein YP_003258801.1 KEGG: rme:Rmet_1474 hypothetical protein YP_003258802.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: bpy:Bphyt_7274 transcriptional regulator, XRE family YP_003258803.1 KEGG: rme:Rmet_1473 retron reverse transcriptase YP_003258804.1 KEGG: vei:Veis_3745 hypothetical protein YP_003258805.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: vei:Veis_3744 UBA/ThiF-type NAD/FAD binding protein YP_003258806.1 KEGG: pna:Pnap_2447 hypothetical protein YP_003258807.1 KEGG: shw:Sputw3181_3992 hypothetical protein YP_003258808.1 PFAM: ATP-binding region ATPase domain protein; KEGG: shm:Shewmr7_1788 ATP-binding region, ATPase-like protein YP_003258809.1 PFAM: integrase; KEGG: pct:PC1_2870 integrase YP_003258810.1 PFAM: MscS Mechanosensitive ion channel; KEGG: eca:ECA3118 mechanosensitive ion channel protein YP_003258811.1 PFAM: aminotransferase class IV; KEGG: eca:ECA3117 D-alanine aminotransferase YP_003258812.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA3116 mandelate racemase/muconate lactonizing enzyme YP_003258813.1 PFAM: aminotransferase class I and II; KEGG: pct:PC1_2866 aminotransferase class I and II YP_003258814.1 TIGRFAM: lipoprotein, PulS/OutS family; PFAM: Chaperone lipoprotein, PulS/OutS; KEGG: eca:ECA3114 general secretion pathway lipoprotein YP_003258815.1 KEGG: eca:ECA3113 general secretion pathway protein YP_003258816.1 PFAM: Fibronectin type III domain protein; glycoside hydrolase family 28; SMART: Fibronectin type III domain protein; KEGG: eca:ECA3111 exo-poly-alpha-D-galacturonosidase YP_003258817.1 TIGRFAM: general secretion pathway protein C; KEGG: pct:PC1_2861 general secretion pathway protein C YP_003258818.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: eca:ECA3109 general secretion pathway protein D YP_003258819.1 KEGG: eca:ECA3108 general secretion pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: ATPase AAA YP_003258820.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system F domain; KEGG: eca:ECA3107 general secretion pathway protein F YP_003258821.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: eca:ECA3106 general secretion pathway protein G YP_003258822.1 TIGRFAM: general secretion pathway protein H; KEGG: eca:ECA3105 general secretion pathway protein H YP_003258823.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: pct:PC1_2855 general secretion pathway protein I YP_003258824.1 TIGRFAM: general secretion pathway protein J; KEGG: eca:ECA3103 general secretion pathway protein J YP_003258825.1 PFAM: general secretion pathway protein K; KEGG: eca:ECA3102 general secretion pathway protein K YP_003258826.1 TIGRFAM: general secretion pathway protein L; PFAM: general secretion pathway L; KEGG: pct:PC1_2852 general secretion pathway protein L YP_003258827.1 PFAM: general secretion pathway protein M; KEGG: eca:ECA3100 general secretion pathway protein M YP_003258828.1 PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; KEGG: eca:ECA3098 type 4 prepilin-like proteins leader peptide processing enzyme YP_003258829.1 PFAM: Luciferase-like, subgroup; KEGG: eca:ECA3097 monooxygenase YP_003258830.1 PFAM: periplasmic binding protein; KEGG: eca:ECA3096 ABC-transporter periplasmic-binding component YP_003258831.1 PFAM: transporter permease; KEGG: eca:ECA3095 ABC transporter permease YP_003258832.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3094 ABC transporter ATP-binding protein YP_003258833.1 KEGG: eca:ECA3093 molybdate ABC transporter periplasmic molybdate-binding protein YP_003258834.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_003258835.1 PFAM: protein of unknown function DUF1234; KEGG: pct:PC1_2842 hypothetical protein YP_003258836.1 KEGG: eca:ECA3090 hypothetical protein YP_003258837.1 KEGG: pct:PC1_2840 hypothetical protein YP_003258838.1 KEGG: eca:ECA3088 hypothetical protein YP_003258839.1 PFAM: Necrosis inducing; KEGG: pct:PC1_2838 Necrosis inducing protein YP_003258840.1 KEGG: pct:PC1_2835 hypothetical protein YP_003258841.1 KEGG: pct:PC1_2834 hypothetical protein YP_003258842.1 KEGG: pct:PC1_2833 hypothetical protein YP_003258843.1 PFAM: VacJ family lipoprotein; KEGG: eca:ECA3083 lipoprotein YP_003258844.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_003258845.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: dac:Daci_5638 LysR family transcriptional regulator YP_003258846.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bam:Bamb_3531 short chain dehydrogenase YP_003258847.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: eca:ECA3081 long-chain fatty acid outer membrane transporter YP_003258848.1 PFAM: conserved hypothetical protein; KEGG: pct:PC1_2823 hypothetical protein YP_003258849.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_003258850.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_003258851.1 PFAM: Spore coat U domain protein; KEGG: eca:ECA3077 hypothetical protein YP_003258852.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: eca:ECA3076 fimbrial usher protein YP_003258853.1 KEGG: eca:ECA3075 fimbrial chaperone YP_003258854.1 PFAM: Spore coat U domain protein; KEGG: eca:ECA3074 hypothetical protein YP_003258855.1 PFAM: Spore coat U domain protein; KEGG: eca:ECA3073 hypothetical protein YP_003258856.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: phosphoglycerate mutase; KEGG: pct:PC1_2814 phosphohistidine phosphatase, SixA YP_003258857.1 PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2; KEGG: pct:PC1_2813 Smr protein/MutS2 YP_003258858.1 involved in methylation of ribosomal protein L3 YP_003258859.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_003258860.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_003258861.1 PFAM: protein of unknown function DUF81; KEGG: eca:ECA3067 hypothetical protein YP_003258862.1 PFAM: protein of unknown function DUF462; KEGG: pct:PC1_2808 hypothetical protein YP_003258863.1 PFAM: YfcL protein; KEGG: pct:PC1_2807 YfcL protein YP_003258864.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_003258865.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_003258866.1 PFAM: alpha/beta hydrolase; KEGG: kpn:KPN_04184 acetyl esterase YP_003258867.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_003258868.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pct:PC1_2803 hypothetical protein YP_003258869.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pct:PC1_2802 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region YP_003258870.1 PFAM: semialdehyde dehydrogenase dimerisation region; semialdehyde dehydrogenase NAD - binding; KEGG: eca:ECA3059 semialdehyde dehydrogenase YP_003258871.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_003258872.1 PFAM: SNARE associated Golgi protein; KEGG: pct:PC1_2799 SNARE associated Golgi protein YP_003258873.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_003258874.1 KEGG: eca:ECA3055 bifunctional folylpolyglutamate synthase/dihydrofolate synthase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein YP_003258875.1 PFAM: sporulation domain protein; KEGG: pct:PC1_2796 sporulation domain protein YP_003258876.1 membrane protein required for colicin V production YP_003258877.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_003258878.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_003258879.1 KEGG: eca:ECA3050 histidine-binding periplasmic protein; TIGRFAM: cationic amino acid ABC transporter periplasmic protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3 YP_003258880.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3049 histidine ABC transporter permease YP_003258881.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_2788 polar amino acid ABC transporter inner membrane protein YP_003258882.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_2787 ABC transporter YP_003258883.1 PFAM: hypothetical protein; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA3046 hypothetical protein YP_003258884.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_003258885.1 PFAM: glutathione S-transferase domain; KEGG: pct:PC1_2784 glutathione S-transferase YP_003258886.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: eca:ECA3043 phosphodiesterase YP_003258887.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA3042 NUDIX hydrolase YP_003258888.1 PFAM: protein of unknown function DUF817; KEGG: eca:ECA3041 hypothetical protein YP_003258889.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_003258890.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_003258891.1 PFAM: protein of unknown function DUF412; KEGG: eca:ECA3038 hypothetical protein YP_003258892.1 PFAM: YfbU family protein; KEGG: pct:PC1_2778 YfbU family protein YP_003258893.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pct:PC1_2777 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_003258894.1 PFAM: citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: eca:ECA3035 sodium/sulfate transporter YP_003258895.1 KEGG: pct:PC1_2775 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_003258896.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_003258897.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pct:PC1_2773 LysR family transcriptional regulator YP_003258898.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258899.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_003258900.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_003258901.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258902.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_003258903.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258904.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258905.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258906.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258907.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258908.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_003258909.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258910.1 Catalyzes the transfer of electrons from NADH to quinone YP_003258911.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: pct:PC1_2759 hypothetical protein YP_003258912.1 KEGG: eca:ECA3014 trehalose-6-phosphate hydrolase; TIGRFAM: alpha,alpha-phosphotrehalase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain YP_003258913.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003258915.1 PFAM: major facilitator superfamily MFS_1; KEGG: spe:Spro_3265 major facilitator transporter YP_003258917.1 KEGG: bph:Bphy_7706 coproporphyrinogen dehydrogenase; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB YP_003258918.1 KEGG: pct:PC1_2756 hypothetical protein YP_003258919.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3012 acetyltransferase YP_003258920.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: pct:PC1_2754 phenazine biosynthesis protein PhzF family YP_003258921.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3010 ABC transporter ATP-binding protein YP_003258922.1 PFAM: TonB-dependent receptor plug; TonB-dependent receptor; KEGG: pct:PC1_2751 TonB-dependent receptor plug YP_003258923.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_003258924.1 PFAM: protein of unknown function DUF1008; KEGG: pct:PC1_2749 hypothetical protein YP_003258925.1 KEGG: pct:PC1_2748 hypothetical protein YP_003258926.1 PFAM: sigma factor YlaC; KEGG: pct:PC1_2747 hypothetical protein YP_003258927.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_003258928.1 PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pct:PC1_2744 GntR family transcriptional regulator YP_003258929.1 required for the formation of active formate dehydrogenase YP_003258930.1 KEGG: eca:ECA3001 hypothetical protein YP_003258931.1 PFAM: protein of unknown function DUF202; KEGG: pct:PC1_2741 hypothetical protein YP_003258932.1 PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: ses:SARI_03961 hypothetical protein YP_003258933.1 PFAM: aldose 1-epimerase; KEGG: ses:SARI_03960 hypothetical protein YP_003258934.1 PFAM: sulfatase; KEGG: ses:SARI_03959 hypothetical protein YP_003258935.1 TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: ses:SARI_03958 hypothetical protein YP_003258936.1 PFAM: radical SAM protein; KEGG: ses:SARI_03135 hypothetical protein YP_003258937.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: pct:PC1_2740 cyd operon protein YbgT YP_003258938.1 TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: eca:ECA2999 cytochrome d ubiquinol oxidase subunit II YP_003258939.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: eca:ECA2998 cytochrome d ubiquinol oxidase subunit I YP_003258940.1 PFAM: tail assembly chaperone gp38; KEGG: pct:PC1_2737 tail assembly chaperone GP38 YP_003258941.1 PFAM: hypothetical protein; KEGG: eca:ECA2996 bacteriophage tail fiber protein YP_003258942.1 PFAM: nitrate and nitrite sensing domain protein; ANTAR domain protein; KEGG: eca:ECA2995 nitrate-and nitrite-responsive positive regulator YP_003258944.1 KEGG: pct:PC1_2733 nitrate-binding protein YP_003258945.1 TIGRFAM: nitrate ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_2732 nitrate ABC transporter inner membrane protein YP_003258946.1 KEGG: eca:ECA2992 nitrate transporter; TIGRFAM: nitrate ABC transporter ATPases C and D; PFAM: ABC transporter related; SMART: ATPase AAA YP_003258947.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: eca:ECA2991 nitrite reductase [NAD(P)H] large subunit YP_003258948.1 PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; molydopterin dinucleotide-binding region; KEGG: eca:ECA2990 nitrate reductase YP_003258949.1 KEGG: pct:PC1_2728 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_003258950.1 PFAM: transposase YhgA family protein; KEGG: pct:PC1_2727 transposase YhgA family protein YP_003258951.1 PFAM: protein of unknown function DUF1456; KEGG: pct:PC1_2726 hypothetical protein YP_003258952.1 PFAM: acireductone dioxygenase; KEGG: eca:ECA2986 oxidase YP_003258953.1 SMART: regulatory protein ArsR; KEGG: eca:ECA2985 transcription regulator ArsR YP_003258954.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: eca:ECA2984 flavoprotein xenobiotic reductase YP_003258955.1 PFAM: protein of unknown function DUF1348; KEGG: pct:PC1_2714 hypothetical protein YP_003258956.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: pct:PC1_2688 mandelate racemase/muconate lactonizing protein YP_003258957.1 PFAM: sulfate transporter; sulfate transporter/antisigma-factor antagonist STAS; xanthine/uracil/vitamin C permease; KEGG: eca:ECA2958 sulfate transporter YP_003258958.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eca:ECA2933 short-chain dehydrogenase YP_003258959.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: eca:ECA2932 outer membrane efflux lipoprotein YP_003258960.1 PFAM: regulatory protein TetR; KEGG: eca:ECA2931 TetR family transcriptional regulator YP_003258961.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: hypothetical protein; KEGG: eca:ECA2930 HlyD family hypothetical protein YP_003258962.1 PFAM: acriflavin resistance protein; KEGG: eca:ECA2929 efflux protein YP_003258963.1 KEGG: dze:Dd1591_1514 integrase YP_003258964.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sed:SeD_A1453 acetyltransferase YP_003258965.1 KEGG: eca:ECA1633 hypothetical protein YP_003258966.1 KEGG: eca:ECA2917 hypothetical protein YP_003258967.1 KEGG: eca:ECA2916 hypothetical protein YP_003258968.1 KEGG: eca:ECA1636 hypothetical protein YP_003258969.1 KEGG: eca:ECA1637 hypothetical protein YP_003258970.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: kpn:KPN_01147 hypothetical protein YP_003258971.1 KEGG: kpe:KPK_3349 ACT domain protein YP_003258972.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: esa:ESA_pESA3p05470 hypothetical protein YP_003258973.1 KEGG: eta:ETA_00510 hypothetical protein YP_003258974.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: eta:ETA_00500 probable transcriptional regulator YP_003258975.1 KEGG: eca:ECA1662 hypothetical protein YP_003258976.1 PFAM: conjugal transfer protein TraD; KEGG: eca:ECA1663 hypothetical protein YP_003258977.1 KEGG: eta:ETA_09590 hypothetical protein YP_003258978.1 KEGG: eta:ETA_09580 hypothetical protein YP_003258979.1 KEGG: eca:ECA1668 type IV prepilin YP_003258980.1 PFAM: Integrase catalytic region; KEGG: net:Neut_2192 integrase catalytic subunit YP_003258981.1 PFAM: transposase IS3/IS911 family protein; KEGG: har:HEAR2248 transposase YP_003258983.1 KEGG: eca:ECA1672A hypothetical protein YP_003258984.1 PFAM: integrase; KEGG: dda:Dd703_2459 integrase YP_003258985.1 PFAM: protein of unknown function DUF980; KEGG: pct:PC1_1479 hypothetical protein YP_003258986.1 PFAM: regulatory protein LysR; KEGG: pct:PC1_2674 LysR family transcriptional regulator YP_003258987.1 PFAM: Sigma-S stabilisation anti-adaptor protein; KEGG: eca:ECA2886 hypothetical protein YP_003258988.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_003258989.1 KEGG: pct:PC1_2671 hypothetical protein YP_003258990.1 PFAM: protein of unknown function DUF2594; KEGG: pct:PC1_2670 hypothetical protein YP_003258991.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_003258992.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_003258993.1 KEGG: pct:PC1_2667 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_003258994.1 PFAM: integrase; KEGG: net:Neut_0006 phage integrase YP_003258995.1 PFAM: KAP P-loop domain protein; KEGG: prw:PsycPRwf_0010 kap P-loop domain-containing protein YP_003258996.1 KEGG: rpf:Rpic12D_2663 hypothetical protein YP_003258997.1 PFAM: DEAD/DEAH box helicase; helicase domain protein; type III restriction protein res subunit; SMART: DEAD/DEAH box helicase ; helicase; KEGG: bxe:Bxe_A1793 helicase-like protein YP_003258998.1 KEGG: bxe:Bxe_A1797 hypothetical protein YP_003259000.1 KEGG: pst:PSPTO_4750 hypothetical protein YP_003259001.1 KEGG: dze:Dd1591_0412 transcriptional regulator, Nlp YP_003259002.1 KEGG: dze:Dd1591_0412 transcriptional regulator, Nlp YP_003259003.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: pct:PC1_0054 type VI secretion system effector, Hcp1 family YP_003259004.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA2867 rhs accessory genetic element YP_003259005.1 PFAM: Domain of unknown function DUF1795; KEGG: eca:ECA4277 hypothetical protein YP_003259006.1 TIGRFAM: hypothetical protein; PFAM: PAAR repeat-containing protein; hypothetical protein; KEGG: eca:ECA2869 rhs protein YP_003259008.1 KEGG: eca:ECA1658 hypothetical protein YP_003259009.1 KEGG: cps:CPS_1649 hypothetical protein YP_003259010.1 PFAM: sigma-54 factor interaction domain-containing protein; ATPase AAA; SMART: AAA ATPase; KEGG: dze:Dd1591_0424 sigma 54 interacting domain protein YP_003259011.1 PFAM: relaxase; protein of unknown function DUF1528; KEGG: dze:Dd1591_0425 relaxase YP_003259012.1 KEGG: pfo:Pfl01_3031 hypothetical protein YP_003259013.1 KEGG: pfo:Pfl01_3030 hypothetical protein YP_003259014.1 KEGG: tau:Tola_2452 hypothetical protein YP_003259015.1 KEGG: dze:Dd1591_0428 hypothetical protein YP_003259016.1 KEGG: dze:Dd1591_0429 hypothetical protein YP_003259017.1 KEGG: dze:Dd1591_0430 hypothetical protein YP_003259018.1 PFAM: protein of unknown function DUF1527; KEGG: dze:Dd1591_0431 protein of unknown function DUF1527 YP_003259019.1 PFAM: protein of unknown function DUF1525; KEGG: dze:Dd1591_0432 protein of unknown function DUF1525 YP_003259020.1 KEGG: bpt:Bpet1364 hypothetical protein YP_003259021.1 KEGG: dze:Dd1591_0433 hypothetical protein YP_003259022.1 PFAM: Domain of unknown function DUF1814; KEGG: dze:Dd1591_0434 domain of unknown function DUF1814 YP_003259023.1 KEGG: dze:Dd1591_0435 hypothetical protein YP_003259024.1 KEGG: dze:Dd1591_0436 secreted protein YP_003259025.1 KEGG: dze:Dd1591_0437 secreted protein YP_003259026.1 KEGG: tau:Tola_2441 secreted protein YP_003259027.1 KEGG: dze:Dd1591_0439 secreted protein YP_003259028.1 KEGG: dze:Dd1591_0440 hypothetical protein YP_003259029.1 KEGG: dze:Dd1591_0441 hypothetical protein YP_003259030.1 KEGG: dze:Dd1591_0442 hypothetical protein YP_003259031.1 PFAM: protein of unknown function, RAQPRD; KEGG: dia:Dtpsy_1172 plasmid conserved hypothetical protein RAQPRD YP_003259033.1 PFAM: ion transporter ; pentapeptide repeat protein; KEGG: dal:Dalk_3538 ion transporter YP_003259034.1 KEGG: dze:Dd1591_0447 hypothetical protein YP_003259035.1 KEGG: dze:Dd1591_0448 hypothetical protein YP_003259036.1 KEGG: dze:Dd1591_0449 hypothetical protein YP_003259037.1 PFAM: lytic transglycosylase catalytic; KEGG: dze:Dd1591_0450 signal peptide YP_003259038.1 KEGG: dze:Dd1591_0451 secreted protein YP_003259039.1 KEGG: dze:Dd1591_0452 hypothetical protein YP_003259040.1 KEGG: dze:Dd1591_0453 secreted protein YP_003259041.1 KEGG: xca:xccb100_2436 hypothetical protein YbjD YP_003259042.1 PFAM: UvrD/REP helicase; KEGG: tau:Tola_2426 UvrD/REP helicase YP_003259043.1 SMART: DEAD/DEAH box helicase; KEGG: dze:Dd1591_0457 DEAD/DEAH box helicase YP_003259044.1 KEGG: dze:Dd1591_0458 hypothetical protein YP_003259045.1 KEGG: dze:Dd1591_0459 hypothetical protein YP_003259046.1 KEGG: dze:Dd1591_0461 hypothetical protein YP_003259047.1 KEGG: dze:Dd1591_0462 hypothetical protein YP_003259048.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: cvi:CV_1243 trans-acting regulatory HvrA protein YP_003259049.1 KEGG: rpf:Rpic12D_0661 hypothetical protein YP_003259050.1 KEGG: dze:Dd1591_0463 hypothetical protein YP_003259051.1 KEGG: dze:Dd1591_0464 hypothetical protein YP_003259053.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: dze:Dd1591_0465 DNA-cytosine methyltransferase YP_003259054.1 KEGG: dze:Dd1591_0466 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein YP_003259055.1 KEGG: dze:Dd1591_0468 hypothetical protein YP_003259056.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_003259057.1 KEGG: dze:Dd1591_0474 hypothetical protein YP_003259058.1 PFAM: Domain of unknown function DUF1845; KEGG: dze:Dd1591_0475 domain of unknown function DUF1845 YP_003259059.1 KEGG: dze:Dd1591_0476 hypothetical protein YP_003259060.1 KEGG: dze:Dd1591_0477 hypothetical protein YP_003259061.1 KEGG: dze:Dd1591_0478 hypothetical protein YP_003259062.1 KEGG: dze:Dd1591_0479 hypothetical protein YP_003259063.1 PFAM: cobyrinic acid ac-diamide synthase; KEGG: tau:Tola_2396 cobyrinic acid ac-diamide synthase YP_003259064.1 PFAM: prophage CP4-57 regulator; KEGG: dze:Dd1591_0481 phage transcriptional regulator, AlpA YP_003259065.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: bpt:Bpet1288 LysR family transcriptional regulator YP_003259066.1 PFAM: integrase; KEGG: eca:ECA2879 integrase YP_003259067.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities YP_003259068.1 PFAM: N-6 DNA methylase; KEGG: stm:STM4525 DNA methylase M YP_003259069.1 PFAM: restriction modification system DNA specificity domain; KEGG: stt:t4574 EcoKI restriction-modification system protein HsdS YP_003259070.1 KEGG: stt:t4573 endoribonuclease SymE YP_003259071.1 PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: dol:Dole_2238 hypothetical protein YP_003259072.1 PFAM: DEAD/DEAH box helicase; protein of unknown function DUF1998; helicase; SMART: DEAD/DEAH box helicase ; helicase; KEGG: sek:SSPA4005 hypothetical protein YP_003259073.1 KEGG: sek:SSPA4006 hypothetical protein YP_003259074.1 KEGG: dze:Dd1591_3691 hypothetical protein YP_003259075.1 KEGG: eic:NT01EI_2039 hypothetical protein YP_003259076.1 KEGG: eic:NT01EI_2038 hypothetical protein YP_003259077.1 KEGG: ppg:PputGB1_4758 labile enterotoxin output A YP_003259078.1 KEGG: ppg:PputGB1_4757 protein of unknown function DUF900 hydrolase family protein YP_003259079.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: dze:Dd1591_1494 transcriptional regulator, TraR/DksA family YP_003259080.1 KEGG: dze:Dd1591_1495 hypothetical protein YP_003259081.1 PFAM: prophage CP4-57 regulator; KEGG: eca:ECA1627 prophage regulatory protein YP_003259082.1 KEGG: dze:Dd1591_1508 hypothetical protein YP_003259084.1 KEGG: dze:Dd1591_1511 transcriptional regulator, Nlp YP_003259085.1 SMART: hypothetical protein; KEGG: dze:Dd1591_1513 XRE family transcriptional regulator YP_003259086.1 SMART: hypothetical protein; KEGG: dze:Dd1591_1513 XRE family transcriptional regulator YP_003259087.1 PFAM: integrase; KEGG: dze:Dd1591_1514 integrase YP_003259088.1 KEGG: hypothetical protein YP_003259089.1 KEGG: pct:PC1_1596 hypothetical protein YP_003259090.1 PFAM: prophage CP4-57 regulator; KEGG: pct:PC1_1597 phage transcriptional regulator, AlpA YP_003259091.1 PFAM: integrase; KEGG: ecs:ECs3512 site specific recombinase YP_003259092.1 PFAM: integrase; KEGG: cko:CKO_03527 hypothetical protein YP_003259093.1 KEGG: ecs:ECs3510 hypothetical protein YP_003259094.1 KEGG: ecs:ECs3509 hypothetical protein YP_003259095.1 KEGG: pct:PC1_1602 hypothetical protein YP_003259096.1 KEGG: pca:Pcar_0163 hypothetical protein YP_003259098.1 PFAM: transposase IS3/IS911 family protein; KEGG: har:HEAR2248 transposase YP_003259099.1 PFAM: Integrase catalytic region; KEGG: net:Neut_2192 integrase catalytic subunit YP_003259100.1 KEGG: pct:PC1_1607 hypothetical protein YP_003259101.1 KEGG: pct:PC1_1608 hypothetical protein YP_003259102.1 KEGG: pct:PC1_1609 hypothetical protein YP_003259103.1 PFAM: relaxase/mobilization nuclease family protein; KEGG: pct:PC1_1610 relaxase/mobilization nuclease family protein YP_003259104.1 KEGG: pct:PC1_1611 hypothetical protein YP_003259107.1 KEGG: pct:PC1_1614 hypothetical protein YP_003259108.1 PFAM: radical SAM protein; KEGG: pct:PC1_1615 radical SAM protein YP_003259109.1 PFAM: radical SAM protein; KEGG: pct:PC1_1616 radical SAM protein YP_003259110.1 KEGG: pct:PC1_1617 hypothetical protein YP_003259111.1 KEGG: pct:PC1_1619 hypothetical protein YP_003259112.1 KEGG: pct:PC1_1620 hypothetical protein YP_003259113.1 KEGG: pct:PC1_1621 hypothetical protein YP_003259115.1 KEGG: psb:Psyr_2650 hypothetical protein YP_003259116.1 PFAM: RimK domain protein ATP-grasp; KEGG: psb:Psyr_2651 hypothetical protein YP_003259117.1 KEGG: psb:Psyr_2652 hypothetical protein YP_003259118.1 KEGG: eta:ETA_14250 hypothetical protein YP_003259120.1 PFAM: FRG domain protein; KEGG: elf:LF82_p282 hypothetical protein YP_003259121.1 PFAM: integrase; KEGG: eca:ECA1679 phage integrase YP_003259122.1 KEGG: eca:ECA2921 hypothetical protein YP_003259123.1 KEGG: eca:ECA2919 hypothetical protein YP_003259124.1 PFAM: prophage CP4-57 regulator; KEGG: eca:ECA2918 phage-related protein YP_003259125.1 KEGG: eca:ECA1634 hypothetical protein YP_003259126.1 KEGG: eca:ECA1635 hypothetical protein YP_003259127.1 KEGG: eca:ECA1636 hypothetical protein YP_003259128.1 KEGG: eca:ECA1637 hypothetical protein YP_003259129.1 KEGG: eca:ECA2913 DNA-binding protein YP_003259130.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: hiq:CGSHiGG_00130 Sel1 domain-containing protein YP_003259131.1 KEGG: eca:ECA1640 hypothetical protein YP_003259132.1 KEGG: set:SEN1991 hypothetical protein YP_003259133.1 KEGG: eca:ECA2910 plasmid replication protein YP_003259134.1 KEGG: eca:ECA1645 hypothetical protein YP_003259135.1 KEGG: eca:ECA1647 hypothetical protein YP_003259136.1 KEGG: pfs:pQBR0096 hypothetical protein YP_003259138.1 KEGG: eca:ECA1654 hypothetical protein YP_003259139.1 KEGG: eca:ECA2904 lipoprotein YP_003259140.1 KEGG: hypothetical protein YP_003259141.1 PFAM: MobA/MobL protein; KEGG: ecq:ECED1_2304 mobilization protein YP_003259143.1 KEGG: eca:ECA2895 hypothetical protein YP_003259144.1 PFAM: conjugal transfer protein TraD; KEGG: eca:ECA1663 hypothetical protein YP_003259147.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: eca:ECA1665 DNA-binding protein Hns YP_003259150.1 KEGG: eca:ECA1666 hypothetical protein YP_003259153.1 PFAM: PilS domain protein; KEGG: ecg:E2348C_2109 predicted type IV pilin-like protein YP_003259154.1 KEGG: eca:ECA1668 type IV prepilin YP_003259155.1 PFAM: S-type Pyocin domain protein; PAAR repeat-containing protein; KEGG: eca:ECA1669 hypothetical protein YP_003259156.1 KEGG: ypb:YPTS_3644 hypothetical protein YP_003259157.1 KEGG: eca:ECA1671 hypothetical protein YP_003259158.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: mpt:Mpe_B0033 hypothetical protein YP_003259159.1 PFAM: integrase; KEGG: dda:Dd703_2459 integrase YP_003259160.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_003259161.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_003259162.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_003259163.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import YP_003259164.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1493 ferric ABC transporter permease YP_003259165.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA1494 ABC transporter iron-binding protein YP_003259166.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1495 regulatory protein YP_003259167.1 KEGG: eca:ECA1496 two-component system sensor histidine kinase; PFAM: MASE1 domain protein; ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein YP_003259168.1 PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: eca:ECA1497 two-component system response regulator protein YP_003259169.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: eca:ECA1498 lipoprotein-28 precursor YP_003259170.1 PFAM: pectate lyase/Amb allergen; SMART: pectate lyase/Amb allergen; KEGG: eca:ECA1499 pectin lyase YP_003259171.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: eca:ECA1500 aspartate racemase YP_003259172.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: eca:ECA1501 LysR family transcriptional regulator YP_003259173.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA1503 proton glutamate symport protein YP_003259174.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: pct:PC1_1383 formate dehydrogenase, subunit alpha YP_003259175.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_1384 methyl-accepting chemotaxis sensory transducer YP_003259176.1 PFAM: iron permease FTR1; KEGG: pct:PC1_1385 iron permease FTR1 YP_003259177.1 PFAM: Ferrous iron transporter; KEGG: pct:PC1_1386 hypothetical protein YP_003259178.1 PFAM: protein of unknown function DUF2318, membrane; YHS domain protein; KEGG: pct:PC1_1387 YHS domain protein YP_003259179.1 PFAM: protein of unknown function DUF214; KEGG: eca:ECA1513 permease YP_003259180.1 PFAM: protein of unknown function DUF214; KEGG: pct:PC1_1389 hypothetical protein YP_003259181.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1515 ABC transporter ATP binding protein YP_003259182.1 PFAM: redoxin; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; KEGG: eca:ECA1516 lipoprotein YP_003259183.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA1517 hypothetical protein YP_003259184.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA1518 AraC family transcription regulator YP_003259185.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1519 transcriptional regulator CysB-like protein YP_003259186.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transporter YP_003259187.1 PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: pct:PC1_1396 iron-containing alcohol dehydrogenase YP_003259188.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1524 ABC transporter permease YP_003259189.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_1398 ABC transporter YP_003259190.1 KEGG: pct:PC1_1399 ABC transporter periplasmic protein YP_003259191.1 PFAM: malate/L-lactate dehydrogenase; KEGG: eca:ECA1527 malate/lactate dehydrogenase YP_003259192.1 PFAM: substrate-binding region of ABC-type glycine betaine transporter; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA1528 taurine-binding periplasmic protein YP_003259193.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1402 binding-protein-dependent transport systems inner membrane component YP_003259194.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1530 taurine transport ATP-binding protein YP_003259195.1 catalyzes the formation of pyruvate from D-cysteine YP_003259196.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: eca:ECA1532 aspartate racemase YP_003259197.1 KEGG: pfs:PFLU0454 hypothetical protein YP_003259198.1 KEGG: ech:ECH_0329 hypothetical protein YP_003259200.1 PFAM: PAAR repeat-containing protein; KEGG: rso:RS01943 hypothetical protein YP_003259202.1 KEGG: sbp:Sbal223_3248 hypothetical protein YP_003259203.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_003259204.1 TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pct:PC1_1411 TonB-dependent heme/hemoglobin receptor family protein YP_003259205.1 PFAM: FecR protein; KEGG: eca:ECA1539 transmembrane sensor protein YP_003259206.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: eca:ECA1540 ECF sigma factor YP_003259207.1 KEGG: eca:ECA1541 hypothetical protein YP_003259208.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_003259209.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_003259210.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_1417 methyl-accepting chemotaxis sensory transducer YP_003259211.1 PFAM: methyltransferase type 12; methyltransferase type 11; O-methyltransferase family 2; KEGG: eca:ECA1544 methyltransferase YP_003259212.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA1545 AraC family transcriptional regulator YP_003259213.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_003259214.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1424 binding-protein-dependent transport systems inner membrane component YP_003259215.1 PFAM: extracellular solute-binding protein family 5; KEGG: pct:PC1_1425 extracellular solute-binding protein family 5 YP_003259216.1 PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_1426 major facilitator superfamily MFS_1 YP_003259217.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1551 ABC transporter ATP binding protein YP_003259218.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1552 ABC transporter ATP-binding protein YP_003259219.1 PFAM: thioredoxin domain; KEGG: eca:ECA1555 hypothetical protein YP_003259220.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_1431 ABC transporter YP_003259221.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1432 binding-protein-dependent transport systems inner membrane component YP_003259222.1 KEGG: eca:ECA1558 sulfate ester transporter periplasmic binding component YP_003259223.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1559 LysR family transcriptional regulator YP_003259224.1 PFAM: CDP-diacylglycerol pyrophosphatase; KEGG: pct:PC1_1435 CDP-diacylglycerol diphosphatase YP_003259225.1 PFAM: Autoinducer-binding domain protein; regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: eca:ECA1561 quorum-sensing transcriptional regulator YP_003259227.1 PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; KEGG: pct:PC1_1449 response regulator receiver modulated CheW protein YP_003259228.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_003259229.1 PFAM: regulatory protein TetR; KEGG: pct:PC1_1451 TetR family transcriptional regulator YP_003259230.1 TIGRFAM: drug resistance transporter Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_1452 drug resistance transporter Bcr/CflA subfamily YP_003259231.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli YP_003259232.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eca:ECA1571 threonine dehydratase catabolic YP_003259233.1 SMART: regulatory protein ArsR; KEGG: eca:ECA1572 transcription regulator ArsR YP_003259234.1 KEGG: eca:ECA2847 hypothetical protein YP_003259235.1 KEGG: pct:PC1_2619 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003259236.1 PFAM: dextransucrase DSRB; KEGG: eca:ECA1682 hypothetical protein YP_003259237.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; KEGG: pct:PC1_2617 methyl-accepting chemotaxis sensory transducer YP_003259238.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pct:PC1_2616 hypothetical protein YP_003259239.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_003259240.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_003259241.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_003259242.1 PFAM: OmpA/MotB domain protein; KEGG: pct:PC1_2612 OmpA/MotB domain protein YP_003259243.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_003259244.1 PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: pct:PC1_2610 CheW protein YP_003259245.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: pct:PC1_2609 methyl-accepting chemotaxis sensory transducer YP_003259246.1 methylates the MCP YP_003259247.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_003259248.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: pct:PC1_2606 response regulator receiver protein YP_003259249.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_003259250.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_003259251.1 membrane protein involved in the flagellar export apparatus YP_003259252.1 PFAM: flagellar FlhE family protein; KEGG: eca:ECA1698 flagellar protein YP_003259253.1 PFAM: FlgN family protein; KEGG: pct:PC1_2601 FlgN family protein YP_003259254.1 regulates the flagellar specific sigma28 transcription factor YP_003259255.1 required for the assembly of the flagellar basal body P-ring YP_003259256.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_003259257.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_003259258.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_003259259.1 the hook connects flagellar basal body to the flagellar filament YP_003259260.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_003259261.1 makes up the distal portion of the flagellar basal body rod YP_003259262.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_003259263.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_003259264.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_003259265.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_003259266.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_003259267.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_003259268.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_003259269.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_003259270.1 TIGRFAM: flagellar biosynthetic protein FliO; PFAM: flagellar biosynthesis protein FliO; KEGG: eca:ECA1717 flagellar protein YP_003259271.1 One of three proteins involved in switching the direction of the flagellar rotation YP_003259272.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_003259273.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_003259274.1 PFAM: flagellar hook-length control protein; KEGG: eca:ECA1721 flagellar hook-length control protein YP_003259275.1 rod/hook and filament chaperone YP_003259276.1 involved in type III protein export during flagellum assembly YP_003259277.1 binds to and inhibits the function of flagella specific ATPase FliI YP_003259278.1 One of three proteins involved in switching the direction of the flagellar rotation YP_003259279.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_003259280.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_003259281.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_003259282.1 flagellin specific chaperone YP_003259283.1 PFAM: flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; flagellar hook-associated protein 2 domain protein; KEGG: ypb:YPTS_1841 flagellar capping protein YP_003259284.1 PFAM: flagellin domain protein; KEGG: reh:H16_B2360 flagellin YP_003259285.1 PFAM: methyltransferase regulatory domain, predicted; methyltransferase type 12; methyltransferase type 11; KEGG: bav:BAV1666 hypothetical protein YP_003259286.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_003259287.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_003259288.1 PFAM: PhoH family protein; KEGG: eca:ECA1741 hypothetical protein YP_003259289.1 PFAM: integrase; KEGG: eca:ECA2750 prophage integrase YP_003259290.1 PFAM: sulfatase; KEGG: eca:ECA2749 sulphatase YP_003259291.1 PFAM: protein of unknown function DUF1414; KEGG: eca:ECA2748 hypothetical protein YP_003259292.1 PFAM: 37kDa nucleoid-associated protein; KEGG: eca:ECA2747 nucleoid-associated protein NdpA YP_003259293.1 KEGG: eca:ECA2746 hypothetical protein YP_003259294.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_003259295.1 PFAM: type III restriction protein res subunit; helicase domain protein; DEAD/DEAH box helicase; SMART: DEAD/DEAH box helicase ; helicase; KEGG: eca:ECA2744 helicase YP_003259296.1 PFAM: protein of unknown function DUF2492; KEGG: eca:ECA2743 hypothetical protein YP_003259297.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_003259298.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_003259299.1 KEGG: eca:ECA2740 hypothetical protein YP_003259300.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2739 ABC-transporter ATP-binding protein YP_003259301.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2738 ABC transporter permease YP_003259302.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1644 binding-protein-dependent transport systems inner membrane component YP_003259303.1 PFAM: extracellular solute-binding protein family 5; KEGG: pct:PC1_1645 extracellular solute-binding protein family 5 YP_003259304.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_003259305.1 PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: eca:ECA2734 membrane-bound phosphatase YP_003259306.1 PFAM: cobalamin synthesis protein P47K; KEGG: pct:PC1_1648 cobalamin synthesis protein P47K YP_003259307.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_003259308.1 PFAM: protein of unknown function UPF0153; KEGG: eca:ECA2731 hypothetical protein YP_003259309.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2730 sugar efflux transporter YP_003259311.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_003259312.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_003259313.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003259314.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_003259315.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pct:PC1_1657 LysR family transcriptional regulator YP_003259316.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA2723 lysine transporter YP_003259317.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: eca:ECA2722 exogenous ferric siderophore TonB-dependent receptor YP_003259318.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor YP_003259319.1 PFAM: inner-membrane translocator; KEGG: eca:ECA2720 ABC transporter permease YP_003259320.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_1662 ABC transporter YP_003259321.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_003259322.1 KEGG: pct:PC1_1664 hypothetical protein YP_003259323.1 PFAM: glutathione S-transferase domain; KEGG: pct:PC1_1665 glutathione S-transferase YP_003259324.1 KEGG: pct:PC1_1666 S-formylglutathione hydrolase; TIGRFAM: S-formylglutathione hydrolase; PFAM: esterase YP_003259325.1 TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES; alcohol dehydrogenase zinc-binding domain protein; KEGG: pct:PC1_1667 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase YP_003259326.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2713 LysR family transcriptional regulator YP_003259327.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: eca:ECA2712 methyl-accepting chemotaxis protein YP_003259328.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_003259329.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: eca:ECA2710 hypothetical protein YP_003259330.1 PFAM: protein of unknown function DUF218; KEGG: pct:PC1_1672 hypothetical protein YP_003259331.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_003259332.1 PFAM: glucose sorbosone dehydrogenase; KEGG: eca:ECA2691 hypothetical protein YP_003259333.1 PFAM: glutathione S-transferase domain; KEGG: eca:ECA2690 glutathione S-transferase YP_003259334.1 PFAM: NLPA lipoprotein; KEGG: eca:ECA2689 lipoprotein YP_003259335.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: pct:PC1_1683 beta-lactamase YP_003259336.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: eca:ECA2685 DeoR family transcriptional regulator YP_003259337.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_003259338.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; TrkA-C domain protein; KEGG: eca:ECA2683 hypothetical protein YP_003259339.1 KEGG: eca:ECA2682 hypothetical protein YP_003259340.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_003259341.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_003259342.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_003259343.1 PFAM: sensory transduction regulator, KEGG: eca:ECA2678 hypothetical protein YP_003259344.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2677 putrescine transporter subunit: periplasmic-binding component of ABC superfamily YP_003259345.1 part of the PotFGHI ATP-dependent putrescine transporter YP_003259346.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2675 putrescine transporter subunit: membrane component of ABC superfamily YP_003259347.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2674 putrescine transporter subunit: membrane component of ABC superfamily YP_003259348.1 KEGG: eca:ECA2673 hypothetical protein YP_003259349.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_003259350.1 KEGG: pct:PC1_1698 cationic amino acid ABC transporter periplasmic protein; TIGRFAM: cationic amino acid ABC transporter periplasmic protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor YP_003259351.1 with ArtPQJI acts to transport arginine across the inner membrane YP_003259352.1 with ArtPMJI transports arginine across the inner membrane YP_003259353.1 KEGG: pct:PC1_1701 cationic amino acid ABC transporter periplasmic protein; TIGRFAM: cationic amino acid ABC transporter periplasmic protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor YP_003259354.1 With ArtMQJI transports arginine across the inner membrane YP_003259355.1 PFAM: protein of unknown function DUF74; KEGG: eca:ECA2666 hypothetical protein YP_003259356.1 KEGG: eca:ECA2665 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2 YP_003259357.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: pct:PC1_1705 NAD-dependent epimerase/dehydratase YP_003259358.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: eca:ECA2663 HCP oxidoreductase, NADH-dependent YP_003259359.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_003259360.1 PFAM: protein of unknown function DUF340 membrane; KEGG: eca:ECA2661 hypothetical protein YP_003259361.1 KEGG: pct:PC1_1709 hypothetical protein YP_003259362.1 KEGG: eca:ECA2659 cold shock-like protein; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein YP_003259363.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_003259364.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_003259365.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: eca:ECA2705 phenazine antibiotic biosynthesis protein YP_003259367.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_003259368.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_003259369.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_003259370.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_003259371.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pct:PC1_1717 thioredoxin reductase YP_003259372.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transporter YP_003259373.1 PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; KEGG: pct:PC1_1719 cell divisionFtsK/SpoIIIE YP_003259374.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_003259375.1 PFAM: ATPase AAA; magnesium chelatase ChlI subunit; SMART: ATPase AAA; KEGG: eca:ECA2645 recombination factor protein RarA YP_003259376.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003259377.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2643 MFS family transporter protein YP_003259378.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2642 LysR family transcriptional regulator YP_003259379.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: eca:ECA2641 permease YP_003259380.1 PFAM: protein of unknown function DUF917; KEGG: eca:ECA2640 hypothetical protein YP_003259381.1 PFAM: hydantoinase/oxoprolinase; hydantoinaseoxoprolinase domain protein; KEGG: pct:PC1_1727 hydantoinase/oxoprolinase YP_003259382.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_003259383.1 KEGG: eca:ECA2597 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical YP_003259384.1 TIGRFAM: formate/nitrite transporter; PFAM: formate/nitrite transporter; KEGG: eca:ECA2596 formate transporter YP_003259385.1 PFAM: protein of unknown function DUF181; KEGG: eca:ECA2595 hypothetical protein YP_003259386.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_003259387.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_003259388.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_003259389.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_003259390.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_003259391.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_003259392.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_003259393.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_003259394.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_003259395.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_003259396.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_003259397.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_003259398.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_003259399.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: eca:ECA2581 hypothetical protein YP_003259400.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; Gp5 domain protein; KEGG: spe:Spro_4187 rhs element Vgr protein YP_003259401.1 KEGG: spe:Spro_4186 hypothetical protein YP_003259404.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA2580 methyl-accepting chemotaxis citrate transducer YP_003259405.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA2579 methyl-accepting chemotaxis citrate transducer YP_003259406.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: pct:PC1_1748 response regulator receiver and unknown domain protein YP_003259407.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: pct:PC1_1749 signal transduction histidine kinase regulating citrate/malate metabolism YP_003259409.1 PFAM: citrate carrier protein; KEGG: pct:PC1_1750 citrate carrier protein YP_003259410.1 PFAM: fumarylacetoacetate hydrolase; KEGG: pct:PC1_1751 fumarylacetoacetate hydrolase YP_003259411.1 KEGG: pct:PC1_1752 citrate lyase ligase; TIGRFAM: citrate lyase ligase; cytidyltransferase-related domain protein; PFAM: citrate lyase ligase domain protein; GCN5-related N-acetyltransferase; SMART: citrate lyase ligase domain protein YP_003259412.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_003259413.1 KEGG: eca:ECA2572 citrate lyase beta chain; TIGRFAM: citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase YP_003259414.1 KEGG: eca:ECA2571 citrate lyase alpha chain; TIGRFAM: citrate lyase subunit alpha; PFAM: citrate lyase subunit alpha YP_003259415.1 KEGG: eca:ECA2570 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; TIGRFAM: holo-ACP synthase CitX; PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase YP_003259416.1 KEGG: pct:PC1_1757 triphosphoribosyl-dephospho-CoA synthase CitG; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG; PFAM: triphosphoribosyl-dephospho-CoA protein YP_003259417.1 PFAM: YcgR family protein; type IV pilus assembly PilZ; KEGG: pct:PC1_1758 YcgR family protein YP_003259418.1 KEGG: eca:ECA2567 hypothetical protein YP_003259419.1 PFAM: amino acid permease-associated region; KEGG: pct:PC1_1760 amino acid permease-associated region YP_003259420.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_003259421.1 PFAM: periplasmic binding protein; KEGG: pct:PC1_1763 periplasmic binding protein YP_003259422.1 PFAM: transporter permease; KEGG: pct:PC1_1764 transporter permease YP_003259423.1 PFAM: transporter permease; KEGG: pct:PC1_1765 transporter permease YP_003259424.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2561 iron ABC transporter ATP-binding protein YP_003259425.1 PFAM: protein of unknown function DUF496; KEGG: pct:PC1_1767 hypothetical protein YP_003259426.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase; KEGG: pct:PC1_1768 DNA internalization-related competence protein ComEC/Rec2 YP_003259427.1 involved in the transport of lipid A across the inner membrane YP_003259428.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_003259429.1 PFAM: protein of unknown function DUF343; KEGG: pct:PC1_1771 hypothetical protein YP_003259430.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_003259431.1 KEGG: eca:ECA2553 pectate lyase YP_003259432.1 KEGG: eca:ECA2552 hypothetical protein YP_003259433.1 PFAM: protein of unknown function DUF218; KEGG: eca:ECA2551 hypothetical protein YP_003259434.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_003259435.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_003259436.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_003259437.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_003259438.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; peptidoglycan-binding protein; KEGG: eca:ECA2546 hypothetical protein YP_003259439.1 PFAM: protein of unknown function DUF882; peptidase M15A; KEGG: eca:ECA2545 hypothetical protein YP_003259440.1 PFAM: beta-lactamase; KEGG: pct:PC1_1782 beta-lactamase YP_003259441.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_003259442.1 PFAM: porin; KEGG: eca:ECA2542 outer membrane protein YP_003259443.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003259444.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_003259446.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: eca:ECA2539 aminopeptidase N YP_003259447.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_003259448.1 PFAM: protein of unknown function DUF1379; KEGG: eca:ECA2537 hypothetical protein YP_003259449.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein; ferredoxin; KEGG: eca:ECA2536 iron-sulfur binding protein YP_003259450.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_003259451.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_003259452.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: pct:PC1_1793 integral membrane protein, PqiA family YP_003259453.1 PFAM: hypothetical protein; KEGG: eca:ECA2532 paraquat-inducible protein B YP_003259454.1 PFAM: protein of unknown function DUF330; KEGG: eca:ECA2531 lipoprotein YP_003259455.1 PFAM: ribosome modulation factor; KEGG: pct:PC1_1796 ribosome modulation factor YP_003259456.1 PFAM: chemotaxis sensory transducer; Cache type 2 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_1797 methyl-accepting chemotaxis sensory transducer with cache sensor YP_003259458.1 KEGG: bph:Bphy_6360 lipoprotein YP_003259459.1 KEGG: pfo:Pfl01_3563 hypothetical protein YP_003259460.1 KEGG: kpu:KP1_0602 hypothetical protein YP_003259461.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: pct:PC1_1798 PHP domain protein YP_003259462.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: eca:ECA2528 hypothetical protein YP_003259463.1 PFAM: protein of unknown function DUF1439; KEGG: pct:PC1_1800 hypothetical protein YP_003259464.1 cofactor involved in the reduction of disulfides YP_003259465.1 Confers resistance to norfloxacin and enoxacin YP_003259466.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA2524 ribosomal-protein-S5-alanine N-acetyltransferase YP_003259467.1 PFAM: protein of unknown function DUF480; KEGG: eca:ECA2523 hypothetical protein YP_003259468.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: eca:ECA2522 virulence factor YP_003259469.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: eca:ECA2521 virulence factor YP_003259470.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_003259471.1 PFAM: protein of unknown function DUF991; KEGG: pct:PC1_1808 hypothetical protein YP_003259472.1 PFAM: CutC family protein; KEGG: eca:ECA2518 copper homeostasis protein CutC YP_003259473.1 KEGG: eca:ECA2517 hypothetical protein YP_003259474.1 KEGG: eca:ECA2516 hypothetical protein YP_003259475.1 KEGG: eca:ECA2515 hypothetical protein YP_003259476.1 TIGRFAM: methyltransferase; PFAM: methyltransferase KEGG: eca:ECA2512 hypothetical protein YP_003259477.1 TIGRFAM: methyltransferase; PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: pct:PC1_1811 methyltransferase YP_003259478.1 KEGG: pct:PC1_1812 hypothetical protein YP_003259479.1 PFAM: protein of unknown function DUF72; KEGG: pct:PC1_1813 hypothetical protein YP_003259480.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: eca:ECA2497 signal transduction protein YP_003259481.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_003259482.1 converts dATP to dAMP and pyrophosphate YP_003259483.1 PFAM: protein of unknown function DUF28; KEGG: pct:PC1_1817 hypothetical protein YP_003259484.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_003259485.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_003259486.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_003259487.1 KEGG: pct:PC1_1821 maltoporin YP_003259488.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIsubunit alpha; KEGG: eca:ECA2489 PTS system, cellobiose-specific IIA component YP_003259489.1 KEGG: pct:PC1_1823 PTS system, lactose/cellobiose family IIC subunit; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC YP_003259490.1 PFAM: regulatory protein LacI; SMART: regulatory protein LacI; KEGG: eca:ECA2487 LacI family transcriptional regulator YP_003259491.1 involved in transport of zinc(II) with ZnuA and C YP_003259492.1 involved in transport of zinc(II) with ZnuA and C YP_003259493.1 involved in transport of zinc(II) with ZnuA and C YP_003259494.1 PFAM: peptidase M23; peptidoglycan-binding lysin domain; Opacity-associated protein A; Opacity-associated protein A domain protein; SMART: peptidoglycan-binding LysM; KEGG: pct:PC1_1828 peptidase M23 YP_003259495.1 transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_003259496.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003259497.1 Represses the expression of the zwf, eda, glp and gap YP_003259498.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_003259499.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_003259500.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_003259501.1 PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller; peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: eca:ECA2476 protease II YP_003259502.1 KEGG: pct:PC1_1836 hypothetical protein YP_003259503.1 PFAM: DNA polymerase II subunit beta; KEGG: eca:ECA2475 DNA polymerase III subunit theta YP_003259504.1 PFAM: ferritin; KEGG: pct:PC1_1838 ferroxidase YP_003259505.1 PFAM: protein of unknown function DUF2511; KEGG: pct:PC1_1839 hypothetical protein YP_003259506.1 KEGG: ypy:YPK_3096 hypothetical protein YP_003259508.1 PFAM: ankyrin; SMART: ankyrin; KEGG: ankyrin repeat containing protein YP_003259510.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: eca:ECA2471 cold shock protein YP_003259511.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yen:YE4108 hypothetical protein YP_003259512.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA2468 hypothetical protein YP_003259513.1 PFAM: malate/L-lactate dehydrogenase; KEGG: pct:PC1_1845 malate/L-lactate dehydrogenase YP_003259514.1 PFAM: Extensin family protein; KEGG: eca:ECA2466 hypothetical protein YP_003259516.1 PFAM: protein of unknown function DUF1482; KEGG: pct:PC1_1847 hypothetical protein YP_003259517.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_003259518.1 PFAM: hypothetical protein; KEGG: pct:PC1_1849 mammalian cell entry related domain protein YP_003259519.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: pct:PC1_1850 integral membrane protein, PqiA family YP_003259520.1 PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: pct:PC1_1851 GAF sensor protein YP_003259521.1 affects solute and DNA transport through an unknown mechanism YP_003259522.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_003259523.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA2458 AraC family transcriptional regulator YP_003259524.1 PFAM: PEBP family protein; KEGG: eca:ECA2457 hypothetical protein YP_003259525.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_003259526.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_003259527.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_003259528.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_003259529.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_003259530.1 PFAM: cupin; SMART: transcription factor jumonji jmjC domain protein; KEGG: pct:PC1_1864 cupin 4 family protein YP_003259531.1 PFAM: PhoQ Sensor domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: pct:PC1_1865 histidine kinase YP_003259532.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_003259533.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_003259534.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_003259535.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_003259536.1 PFAM: NUDIX hydrolase; KEGG: pct:PC1_1870 NUDIX hydrolase YP_003259537.1 PFAM: pseudouridine synthase; KEGG: pct:PC1_1871 pseudouridine synthase YP_003259538.1 Converts isocitrate to alpha ketoglutarate YP_003259540.1 PFAM: transposase IS3/IS911 family protein; KEGG: mlo:msr5972 transposase YP_003259541.1 PFAM: transposase IS200-family protein; KEGG: ypg:YpAngola_A3481 IS1541, transposase YP_003259542.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA2438 electron transporter YP_003259543.1 PFAM: Mor transcription activator domain protein; KEGG: eca:ECA2437 regulator of pectin lyase production YP_003259544.1 PFAM: hypothetical protein; peptidase S24/S26A/S26B, conserved region; SMART: hypothetical protein; KEGG: eca:ECA2435 regulator of pectin lyase production YP_003259545.1 KEGG: eca:ECA2434 hypothetical protein YP_003259546.1 KEGG: eca:ECA2433 signaling protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; hypothetical protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein YP_003259547.1 KEGG: eca:ECA2432 two-component sensor kinase; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein YP_003259548.1 PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; KEGG: eca:ECA2431 two-component response regulator YP_003259549.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2430 hypothetical protein YP_003259550.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2429 glycerol-3-phosphate-binding periplasmic protein precursor YP_003259551.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: eca:ECA2428 glycerophosphoryl diester phosphodiesterase YP_003259552.1 metalloprotease YP_003259553.1 KEGG: eca:ECA2426 oligogalacturonate lyase YP_003259554.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: pct:PC1_1885 transcriptional regulator, IclR family YP_003259555.1 KEGG: eca:ECA2424 hypothetical protein YP_003259556.1 PFAM: amino acid permease-associated region; KEGG: pct:PC1_1887 amino acid permease-associated region YP_003259557.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003259558.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_003259559.1 TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: eca:ECA2420 50S ribosomal protein L35 YP_003259560.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_003259561.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_003259562.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_003259563.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_003259564.1 PFAM: GCN5-related N-acetyltransferase; KEGG: dde:Dde_3024 acetyltransferase YP_003259565.1 KEGG: pct:PC1_1895 hypothetical protein YP_003259566.1 PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; KEGG: eca:ECA2414 ABC transporter ATP-binding protein YP_003259567.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA2413 hypothetical protein YP_003259568.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_003259569.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_003259570.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA2410 sodium:dicarboxylate symporter YP_003259571.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: pct:PC1_1901 membrane-bound metal-dependent hydrolase YP_003259572.1 KEGG: pct:PC1_1902 pectin acetylesterase YP_003259573.1 PFAM: oligogalacturonate-specific porin; KEGG: eca:ECA2407 oligogalacturonate-specific porin YP_003259574.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2406 periplasmic pectic oligomers binding protein YP_003259575.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: eca:ECA2405 ABC transporter ATP-binding protein YP_003259576.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1906 binding-protein-dependent transport systems inner membrane component YP_003259577.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1907 binding-protein-dependent transport systems inner membrane component YP_003259578.1 PFAM: periplasmic pectate lyase; KEGG: eca:ECA2402 pectate disaccharide-lyase YP_003259579.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_003259580.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_003259581.1 PFAM: cupin; KEGG: pct:PC1_1911 cupin 2 conserved barrel domain protein YP_003259582.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_003259583.1 KEGG: pct:PC1_1914 hypothetical protein YP_003259584.1 PFAM: fructosamine/ketosamine-3-kinase; aminoglycoside phosphotransferase; KEGG: pct:PC1_1915 fructosamine kinase YP_003259585.1 PFAM: ABC transporter; transporter permease protein; KEGG: eca:ECA2395 chelated iron transporter membrane protein YP_003259586.1 PFAM: ABC transporter; transporter permease protein; KEGG: eca:ECA2394 chelated iron transporter membrane protein YP_003259587.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA2393 chelated iron transporter membrane protein YP_003259588.1 PFAM: periplasmic solute binding protein; KEGG: eca:ECA2392 periplasmic chelated iron-binding protein YP_003259589.1 KEGG: yen:YE1764 hypothetical protein YP_003259590.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sgl:SG1320 cold shock-like protein CspC YP_003259591.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_003259592.1 PFAM: protein of unknown function DUF204; KEGG: pct:PC1_1922 hypothetical protein YP_003259593.1 PFAM: protein of unknown function DUF986; KEGG: eca:ECA2388 hypothetical protein YP_003259594.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_003259595.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: eca:ECA2386 PTS system, mannose-specific IIC component YP_003259596.1 KEGG: pct:PC1_1926 PTS system, mannose/fructose/sorbose family, IIsubunit beta; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIsubunit alpha; PFAM: PTS system sorbose subfamily IIB component; PTS system fructose subfamily IIA component YP_003259597.1 PFAM: integral membrane protein TerC; CBS domain containing protein; transporter-associated region; KEGG: eca:ECA2384 hypothetical protein YP_003259598.1 KEGG: eum:ECUMN_4194 hypothetical protein YP_003259599.1 PFAM: transposase IS200-family protein; KEGG: ypi:YpsIP31758_3905 IS1541, transposase YP_003259600.1 KEGG: pct:PC1_1928 L-serine dehydratase; TIGRFAM: L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_003259601.1 PFAM: NUDIX hydrolase; KEGG: pct:PC1_1929 NUDIX hydrolase YP_003259602.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: chorismate binding-like; anthranilate synthase component I domain protein; KEGG: eca:ECA2378 para-aminobenzoate synthase component I YP_003259603.1 PFAM: protein of unknown function UPF0181; KEGG: eca:ECA2377 hypothetical protein YP_003259604.1 PFAM: endoribonuclease L-PSP; KEGG: pct:PC1_1932 endoribonuclease L-PSP YP_003259605.1 SMART: helicase c2; DEAD/DEAH box helicase; KEGG: eca:ECA2375 ATP-dependent helicase YP_003259606.1 PFAM: peptidase M22 glycoprotease; KEGG: eca:ECA2374 hypothetical protein YP_003259607.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: pct:PC1_1935 outer membrane lipoprotein, Slp family YP_003259608.1 Activates fatty acids by binding to coenzyme A YP_003259609.1 KEGG: eca:ECA2371 ribonuclease D; TIGRFAM: ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein YP_003259611.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_003259612.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_003259613.1 blocks the formation of polar Z-ring septums YP_003259614.1 PFAM: protein of unknown function DUF709; KEGG: eca:ECA2367 hypothetical protein YP_003259615.1 PFAM: fumarylacetoacetate hydrolase; KEGG: pct:PC1_1942 fumarylacetoacetate hydrolase YP_003259616.1 PFAM: protein of unknown function UPF0153; KEGG: pct:PC1_1943 hypothetical protein YP_003259617.1 KEGG: pct:PC1_1944 hypothetical protein YP_003259618.1 KEGG: pct:PC1_1945 DNA polymerase III subunit theta YP_003259619.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_003259620.1 involved in regulation of intracellular pH under alkaline conditions YP_003259621.1 Multifunctional regulator of fatty acid metabolism YP_003259622.1 PFAM: SpoVR family protein; KEGG: pct:PC1_1949 SpoVR family protein YP_003259623.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: eca:ECA2358 aldolase YP_003259624.1 KEGG: eca:ECA2357 kinase YP_003259625.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: eca:ECA2356 sugar phosphotransferase enzyme IIA component YP_003259626.1 KEGG: eca:ECA2355 hypothetical protein YP_003259627.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_003259628.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: eca:ECA2353 hypothetical protein YP_003259629.1 PFAM: phosphofructokinase; KEGG: eca:ECA2352 6-phosphofructokinase isozyme II YP_003259630.1 catalyzes the oxidative deamination of D-amino acids YP_003259631.1 TIGRFAM: drug resistance transporter Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA2350 transporter YP_003259632.1 PFAM: hemerythrin HHE cation binding domain protein; KEGG: pct:PC1_1959 hemerythrin HHE cation binding domain protein YP_003259633.1 PFAM: protein of unknown function DUF444; KEGG: pct:PC1_1960 hypothetical protein YP_003259634.1 PFAM: PrkA AAA domain protein; PrkA serine kinase; SMART: PrkA AAA domain protein; KEGG: eca:ECA2348 hypothetical protein YP_003259635.1 PFAM: MltA-interacting MipA family protein; KEGG: eca:ECA2347 MltA-interacting protein YP_003259636.1 PFAM: aldo/keto reductase; KEGG: pct:PC1_1963 aldo/keto reductase YP_003259637.1 PFAM: aldose 1-epimerase; KEGG: pct:PC1_1964 aldose 1-epimerase YP_003259638.1 KEGG: eca:ECA2344 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_003259639.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_003259640.1 PFAM: protein of unknown function DUF1315; KEGG: pct:PC1_1967 hypothetical protein YP_003259641.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_003259642.1 converts asparagine to aspartate and ammonia YP_003259643.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_003259644.1 PFAM: nitroreductase; KEGG: pct:PC1_1971 nitroreductase YP_003259645.1 decatenates replicating daughter chromosomes YP_003259646.1 PFAM: protein of unknown function DUF1496; KEGG: eca:ECA2336 hypothetical protein YP_003259647.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_003259648.1 PFAM: protein of unknown function UPF0126; KEGG: eca:ECA2334 hypothetical protein YP_003259649.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: dze:Dd1591_4093 type VI secretion system effector, Hcp1 family YP_003259651.1 KEGG: ype:YPO0523 hypothetical protein YP_003259652.1 KEGG: ypy:YPK_3541 hypothetical protein YP_003259653.1 KEGG: ypi:YpsIP31758_1345 hypothetical protein YP_003259654.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_003259655.1 PFAM: SEC-C motif domain protein; KEGG: pct:PC1_1977 sec-C motif domain protein YP_003259656.1 PFAM: patatin; KEGG: eca:ECA2331 hypothetical protein YP_003259657.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: eca:ECA2330 response regulator of RpoS YP_003259658.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_003259659.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: pct:PC1_1981 histone family protein nucleoid-structuring protein H-NS YP_003259660.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_003259661.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: eca:ECA2326 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_003259662.1 PFAM: extracellular solute-binding protein family 5; KEGG: pct:PC1_1984 extracellular solute-binding protein family 5 YP_003259663.1 PFAM: extracellular solute-binding protein family 5; KEGG: pct:PC1_1985 extracellular solute-binding protein family 5 YP_003259664.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1986 binding-protein-dependent transport systems inner membrane component YP_003259665.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1987 binding-protein-dependent transport systems inner membrane component YP_003259666.1 KEGG: pct:PC1_1988 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA YP_003259667.1 KEGG: pct:PC1_1989 oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA YP_003259668.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_003259669.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_003259670.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: eca:ECA2317 methyl-accepting chemotaxis protein YP_003259671.1 PFAM: YCII-related; KEGG: eca:ECA2316 hypothetical protein YP_003259672.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_003259673.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_003259674.1 Involved in cell division; probably involved in intracellular septation YP_003259675.1 PFAM: protein of unknown function UPF0259; KEGG: pct:PC1_1998 hypothetical protein YP_003259676.1 receptor for colicin S4 YP_003259677.1 PFAM: oligogalacturonate-specific porin; KEGG: eca:ECA2302 oligogalacturonate-specific porin YP_003259678.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_003259679.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_003259680.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_003259681.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_003259682.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_003259683.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_003259684.1 SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA2295 AraC family transcription regulator YP_003259685.1 PFAM: glycosyl transferase family 2; KEGG: eca:ECA2294 glycosyl transferase YP_003259686.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: eca:ECA2293 phosphoesterase YP_003259687.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: eca:ECA2292 hypothetical protein YP_003259688.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_003259689.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_003259690.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pct:PC1_2012 short-chain dehydrogenase/reductase SDR YP_003259691.1 SohB; periplasmic protein; member of the peptidase S49 family YP_003259692.1 PFAM: protein of unknown function DUF2498; KEGG: eca:ECA2287 hypothetical protein YP_003259693.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_003259694.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_003259695.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_003259696.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_003259697.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_003259698.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_003259699.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_003259700.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_003259701.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_003259702.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: pct:PC1_2025 electron transport complex, RnfABCDGE type, subunit alpha YP_003259703.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_003259704.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_003259705.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_003259706.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA2273 L-arabinose-binding periplasmic protein YP_003259707.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_003259708.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_003259709.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_003259710.1 PFAM: oxidoreductase domain protein; semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: pct:PC1_2033 oxidoreductase domain protein YP_003259711.1 PFAM: sodium symporter; KEGG: eca:ECA2268 sodium bile acid symporter YP_003259712.1 PFAM: protein of unknown function DUF1176; KEGG: pmy:Pmen_3175 hypothetical protein YP_003259713.1 PFAM: Calcium/calmodulin dependent protein kinase II association-domain protein; KEGG: pct:PC1_2035 calcium/calmodulin dependent protein kinase II association-domain protein YP_003259714.1 catalyzes the formation of inosine from adenosine YP_003259715.1 KEGG: pct:PC1_2037 bile acid:sodium symporter YP_003259716.1 PFAM: protein of unknown function DUF945; KEGG: pct:PC1_2038 hypothetical protein YP_003259717.1 KEGG: eca:ECA2263 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I YP_003259718.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_003259719.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_003259720.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2260 transporter YP_003259721.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2259 LysR family transcriptional regulator YP_003259722.1 PFAM: ROK family protein; KEGG: eca:ECA2258 transcriptional regulator YP_003259723.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_003259724.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_2046 drug resistance transporter EmrB/QacA subfamily YP_003259725.1 PFAM: protein of unknown function DUF1161; KEGG: eca:ECA2255 hypothetical protein YP_003259726.1 KEGG: pct:PC1_2048 lipoprotein YP_003259727.1 PFAM: protein of unknown function DUF1283; KEGG: pct:PC1_2049 hypothetical protein YP_003259728.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_003259729.1 PFAM: aminotransferase class I and II; KEGG: eca:ECA2250 aminotransferase YP_003259730.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_003259731.1 PFAM: pyridoxal-dependent decarboxylase; KEGG: pct:PC1_2059 pyridoxal-dependent decarboxylase YP_003259732.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_003259733.1 PFAM: protein of unknown function DUF187; KEGG: eca:ECA2240 lipoprotein YP_003259734.1 PFAM: protein of unknown function DUF2132; KEGG: eca:ECA2239 hypothetical protein YP_003259736.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: ebw:BWG_1235 inner membrane protein YP_003259737.1 KEGG: ecl:EcolC_2248 hypothetical protein YP_003259738.1 PFAM: Dual specificity protein phosphatase; phosphoesterase PA-phosphatase related; SMART: Dual specificity phosphatase, subgroup, catalytic domain; KEGG: ecl:EcolC_2247 dual specificity phosphatase YP_003259739.1 KEGG: ypb:YPTS_1097 hypothetical protein YP_003259740.1 KEGG: eca:ECA2237 hypothetical protein YP_003259741.1 KEGG: eca:ECA2236 hypothetical protein YP_003259742.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: mms:mma_1110 short-chain dehydrogenase YP_003259743.1 PFAM: YCII-related; KEGG: pst:PSPTO_4066 hypothetical protein YP_003259744.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bch:Bcen2424_3218 short-chain dehydrogenase/reductase SDR YP_003259746.1 PFAM: helix-turn-helix HxlR type; KEGG: eca:ECA2235 transcriptional regulator YP_003259747.1 PFAM: alpha/beta hydrolase fold; KEGG: eca:ECA2233 hydrolase YP_003259748.1 KEGG: eca:ECA2228 hypothetical protein YP_003259749.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_2086 methyl-accepting chemotaxis sensory transducer YP_003259750.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA2225 acetyltransferase YP_003259751.1 PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_2088 major facilitator superfamily MFS_1 YP_003259752.1 PFAM: regulatory protein TetR; KEGG: pct:PC1_2089 TetR family transcriptional regulator YP_003259753.1 PFAM: cytochrome b562; KEGG: pct:PC1_2090 cytochrome b562 YP_003259754.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1479 LysR family transcriptional regulator YP_003259755.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: eca:ECA1480 zinc-binding oxidoreductase YP_003259756.1 PFAM: Rare lipoprotein A; KEGG: eca:ECA2220 cellulase YP_003259757.1 KEGG: eca:ECA2219 virulence effector protein YP_003259758.1 PFAM: virulence protein SrfB; KEGG: pct:PC1_2094 virulence protein SrfB YP_003259759.1 PFAM: virulence effector, SrfC; KEGG: pct:PC1_2095 virulence factor YP_003259760.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: cko:CKO_01684 hypothetical protein YP_003259761.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons YP_003259762.1 TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: cko:CKO_04530 hypothetical protein YP_003259763.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport YP_003259764.1 PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: cko:CKO_04532 hypothetical protein YP_003259765.1 PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: cko:CKO_04533 hypothetical protein YP_003259766.1 PFAM: PTS system fructose subfamily IIA component; KEGG: cko:CKO_04534 hypothetical protein YP_003259767.1 KEGG: ecw:EcE24377A_3617 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_003259768.1 TIGRFAM: sugar isomerase, AgaS family; PFAM: sugar isomerase (SIS); KEGG: cko:CKO_04536 hypothetical protein YP_003259769.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_003259770.1 KEGG: ecc:c1174 hypothetical protein YP_003259771.1 PFAM: extracellular solute-binding protein family 1; KEGG: pct:PC1_2102 extracellular solute-binding protein family 1 YP_003259772.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: eca:ECA2209 oxidoreductase YP_003259773.1 KEGG: eca:ECA2208 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; methylguanine DNA methyltransferase ribonuclease domain protein YP_003259774.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_003259775.1 with UspC and UspD is involved in resistance to UV irradiation YP_003259776.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 subunit betas; AB-stereospecific enzyme YP_003259777.1 forms a tetramer composed of 2 subunit alphas and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_003259778.1 PFAM: protein of unknown function DUF1471; KEGG: eca:ECA2203 hypothetical protein YP_003259779.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_003259780.1 KEGG: eca:ECA2193 transcriptional regulator YP_003259781.1 PFAM: invasion gene expression up-regulator SirB; KEGG: eca:ECA2192 hypothetical protein YP_003259782.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_003259783.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_003259784.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_003259785.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_003259786.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_003259787.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_003259788.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_003259789.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_003259790.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_003259792.1 KEGG: ent:Ent638_1538 lipoprotein YP_003259793.1 KEGG: ent:Ent638_1537 hypothetical protein YP_003259794.1 KEGG: sec:SC3448 hypothetical protein YP_003259795.1 KEGG: ypy:YPK_0771 hypothetical protein YP_003259796.1 KEGG: bam:Bamb_0369 hypothetical protein YP_003259800.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: eca:ECA3392 hypothetical protein YP_003259801.1 KEGG: dze:Dd1591_1505 hypothetical protein YP_003259802.1 PFAM: RHS protein; hypothetical protein; KEGG: esa:ESA_03913 hypothetical protein YP_003259803.1 KEGG: eta:ETA_06440 lipoprotein YP_003259804.1 PFAM: ankyrin; SMART: ankyrin; KEGG: eta:ETA_06440 lipoprotein YP_003259805.1 KEGG: esa:ESA_03915 hypothetical protein YP_003259806.1 PFAM: protein of unknown function DUF2169; KEGG: esa:ESA_03916 hypothetical protein YP_003259807.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; Gp5 domain protein; KEGG: eta:ETA_06410 rhs element Vgr protein subfamily YP_003259808.1 KEGG: spe:Spro_4188 hypothetical protein YP_003259809.1 KEGG: spe:Spro_4189 hypothetical protein YP_003259810.1 PFAM: pentapeptide repeat protein; KEGG: spe:Spro_4190 pentapeptide repeat-containing protein YP_003259811.1 PFAM: protein of unknown function DUF2169; pentapeptide repeat protein; KEGG: spe:Spro_4191 pentapeptide repeat-containing protein YP_003259815.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: spe:Spro_4187 rhs element Vgr protein YP_003259816.1 PFAM: tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: eta:ETA_06360 serine/threonine protein kinase YP_003259817.1 KEGG: eta:ETA_06350 ClpA/B-type chaperone; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; ATPase AAA; Clp domain protein; SMART: ATPase AAA YP_003259818.1 TIGRFAM: type VI hypothetical protein, VC_A0111 family; PFAM: protein of unknown function DUF1305; KEGG: esa:ESA_03922 hypothetical protein YP_003259819.1 TIGRFAM: type VI hypothetical protein, VC_A0110 family; PFAM: protein of unknown function DUF879; KEGG: eta:ETA_06310 hypothetical protein YP_003259820.1 TIGRFAM: type VI secretion system lysozyme-related protein; PFAM: GPW/gp25 family protein; KEGG: eta:ETA_06300 hypothetical protein YP_003259821.1 PFAM: virulence protein SciE type; KEGG: eta:ETA_06290 hypothetical protein YP_003259822.1 KEGG: eta:ETA_06280 hypothetical protein YP_003259823.1 PFAM: protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: eta:ETA_06270 protein phosphatase 2C-like YP_003259824.1 TIGRFAM: type VI secretion system FHA domain protein; PFAM: Forkhead-associated protein; KEGG: eta:ETA_06260 forkhead-associated (FHA) protein YP_003259826.1 KEGG: cla:Cla_0841 hypothetical protein YP_003259827.1 PFAM: protein of unknown function DUF796; KEGG: esa:ESA_03934 hypothetical protein YP_003259828.1 TIGRFAM: type VI hypothetical protein, EvpB/VC_A0108 family; PFAM: protein of unknown function DUF877; KEGG: esa:ESA_03941 hypothetical protein YP_003259829.1 TIGRFAM: type VI hypothetical protein, VC_A0107 family; PFAM: conserved hypothetical protein; KEGG: eta:ETA_06170 hypothetical protein YP_003259830.1 TIGRFAM: type VI secretion-associated protein, ImpA family; PFAM: ImpA domain protein; KEGG: eta:ETA_06160 hypothetical protein YP_003259831.1 TIGRFAM: type VI secretion-associated protein, BMA_A0400 family; PFAM: type VI secretion system-associated, BMAA0400; KEGG: esa:ESA_03944 hypothetical protein YP_003259832.1 TIGRFAM: type VI hypothetical protein IcmF; PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: eta:ETA_06140 hypothetical protein YP_003259833.1 TIGRFAM: type IV / VI secretion system protein, DotU family; type VI secretion system OmpA/MotB family protein; PFAM: type IV / VI secretion system, DotU; OmpA/MotB domain protein; KEGG: eta:ETA_06130 OmpA family protein YP_003259834.1 TIGRFAM: type VI hypothetical protein, VC_A0114 family; PFAM: protein of unknown function DUF876; KEGG: esa:ESA_03947 hypothetical protein YP_003259835.1 TIGRFAM: type VI secretion lipoprotein, VC_A0113 family; KEGG: esa:ESA_03948 hypothetical protein YP_003259836.1 KEGG: esa:ESA_03949 hypothetical protein YP_003259837.1 KEGG: pct:PC1_2131 hypothetical protein YP_003259838.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: cko:CKO_00951 hypothetical protein YP_003259839.1 PFAM: ABC transporter; KEGG: mlo:mll8314 ABC transporter permease YP_003259840.1 PFAM: periplasmic solute binding protein; KEGG: cko:CKO_00949 hypothetical protein YP_003259841.1 KEGG: cko:CKO_00948 hypothetical protein YP_003259842.1 KEGG: eca:ECA2172 hypothetical protein YP_003259843.1 KEGG: eca:ECA2171 hypothetical protein YP_003259844.1 KEGG: eca:ECA2170 hypothetical protein YP_003259845.1 KEGG: hch:HCH_02830 hypothetical protein YP_003259846.1 KEGG: eca:ECA2169 hypothetical protein YP_003259847.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pct:PC1_2137 glyoxalase/bleomycin resistance protein/dioxygenase YP_003259848.1 TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase; KEGG: pct:PC1_2138 histidinol-phosphate phosphatase YP_003259849.1 PFAM: glycoside hydrolase family 1; KEGG: pct:PC1_2140 glycoside hydrolase family 1 YP_003259850.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003259851.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA2164 asc operon repressor YP_003259852.1 KEGG: pct:PC1_2144 hypothetical protein YP_003259853.1 PFAM: protein of unknown function DUF1706; KEGG: eca:ECA2162 hypothetical protein YP_003259854.1 TIGRFAM: luciferase family oxidoreductase, group 1; PFAM: Luciferase-like, subgroup; KEGG: eca:ECA2161 luciferase-like monooxygenase YP_003259855.1 KEGG: eca:ECA2160 peptidase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_003259856.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: eca:ECA2159 4-hydroxyphenylacetate 3-monooxygenase, reductase component YP_003259857.1 KEGG: pct:PC1_2149 hypothetical protein YP_003259858.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA2157 ABC transporter substrate binding protein YP_003259859.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: pct:PC1_2151 extracellular solute-binding protein family 3 YP_003259860.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA2155 acetyltransferase YP_003259861.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2154 ABC transporter permease YP_003259862.1 PFAM: ABC transporter; SMC domain protein; SMART: ATPase AAA; KEGG: pct:PC1_2154 ABC transporter YP_003259863.1 PFAM: hypothetical protein; KEGG: eca:ECA2150 hypothetical protein YP_003259864.1 KEGG: pct:PC1_2157 UreA ABC transporter ATP-binding protein UrtE; TIGRFAM: urea ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA YP_003259865.1 TIGRFAM: urea ABC transporter ATP-binding protein; PFAM: ABC transporter; KEGG: pct:PC1_2158 UreA ABC transporter ATP-binding protein UrtD YP_003259866.1 TIGRFAM: urea ABC transporter permease; PFAM: inner-membrane translocator; KEGG: eca:ECA2146 branched-chain amino acid transporter, permease YP_003259867.1 TIGRFAM: urea ABC transporter permease; PFAM: inner-membrane translocator; KEGG: pct:PC1_2160 UreA ABC transporter permease UrtB YP_003259868.1 TIGRFAM: urea ABC transporter substrate-binding protein; PFAM: extracellular ligand-binding receptor; KEGG: pct:PC1_2161 UreA ABC transporter UreA binding protein YP_003259869.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pct:PC1_2162 transcriptional regulator, GntR family YP_003259870.1 KEGG: eca:ECA2142 UreA amidolyase; TIGRFAM: urea carboxylase; urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; allophanate hydrolase subunit 1; biotin/lipoyl attachment domain-containing protein; carbamoyl-phosphate synthetase large chain domain protein; SMART: allophanate hydrolase subunit 2; allophanate hydrolase subunit 1 YP_003259871.1 catalyzes the hydrolysis of allophanate YP_003259872.1 PFAM: glycoside hydrolase family 43; KEGG: kpe:KPK_0598 xylan 1,4-beta-xylosidase YP_003259873.1 uncharacterized member of the GPH family of galactose-pentose-hexuronide transporters YP_003259874.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: kpe:KPK_0599 transcriptional regulator, AraC family YP_003259875.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: pct:PC1_2165 oxidoreductase domain protein YP_003259876.1 KEGG: eca:ECA2139 hypothetical protein YP_003259877.1 PFAM: oligogalacturonate-specific porin; KEGG: pct:PC1_2168 oligogalacturonate-specific porin YP_003259878.1 PFAM: oligogalacturonate-specific porin; KEGG: pct:PC1_2169 oligogalacturonate-specific porin YP_003259879.1 PFAM: periplasmic pectate lyase; KEGG: pct:PC1_2170 pectate lyase YP_003259880.1 PFAM: extracellular solute-binding protein family 1; KEGG: pct:PC1_2171 extracellular solute-binding protein family 1 YP_003259882.1 KEGG: ank:AnaeK_3328 hypothetical protein YP_003259883.1 KEGG: eca:ECA0397 hypothetical protein YP_003259884.1 KEGG: eca:ECA0398 hypothetical protein YP_003259886.1 PFAM: transposase IS200-family protein; KEGG: ypk:y1204 transposase YP_003259887.1 KEGG: ecz:ECS88_0034 hypothetical protein YP_003259888.1 KEGG: pay:PAU_00446 hypothetical protein YP_003259889.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentous haemagglutinin domain protein; Haemagluttinin repeat-containing protein; KEGG: eca:ECA2118 hemolysin/hemagglutinin-like protein HecA precursor YP_003259890.1 PFAM: polypeptide-transport-associated domain protein ShlB-type; Hemolysin activator HlyB domain protein; KEGG: eca:ECA2116 hemolysin activator protein YP_003259891.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA2115 transcriptional regulator YP_003259892.1 KEGG: pfs:PFLU3607 hypothetical protein YP_003259893.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: eca:ECA2091 signaling membrane protein YP_003259895.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA2075 LysR family transcriptional regulator YP_003259896.1 PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: eca:ECA2074 hypothetical protein YP_003259897.1 PFAM: Bor family protein; KEGG: eca:ECA2067 lipoprotein YP_003259898.1 PFAM: NLPA lipoprotein; KEGG: pct:PC1_2218 NlpA lipoprotein YP_003259899.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: pct:PC1_2219 mandelate racemase/muconate lactonizing protein YP_003259900.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2064 ABC transporter permease YP_003259901.1 PFAM: ABC transporter; NIL domain; SMART: AAA ATPase; KEGG: eca:ECA2063 ABC transporter ATP-binding protein YP_003259902.1 PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: dda:Dd703_2186 haloacid dehalogenase domain protein hydrolase YP_003259903.1 PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: eca:ECA2062 phosphatase YP_003259904.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA2061 methyl-accepting chemotaxis protein YP_003259905.1 PFAM: aminotransferase class-III; KEGG: pct:PC1_2224 aminotransferase class-III YP_003259906.1 PFAM: aminoglycoside phosphotransferase; KEGG: eca:ECA2059 phosphotransferase YP_003259907.1 PFAM: short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: pct:PC1_2226 short-chain dehydrogenase/reductase SDR YP_003259908.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA2057 transporter, permease protein YP_003259909.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_2229 binding-protein-dependent transport systems inner membrane component YP_003259910.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA2055 transporter, periplasmic solute-binding protein YP_003259911.1 KEGG: eca:ECA2054 succinate-semialdehyde dehydrogenase [NADP+]; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_003259912.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_003259913.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: eca:ECA2052 GntR family transcriptional regulator YP_003259914.1 KEGG: pct:PC1_2235 spermidine/putrescine ABC transporter ATPase; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA YP_003259915.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA2050 hypothetical protein YP_003259916.1 KEGG: eca:ECA2049 hypothetical protein YP_003259917.1 PFAM: hypothetical protein; KEGG: eca:ECA2048 hypothetical protein YP_003259918.1 PFAM: protein of unknown function DUF1501; KEGG: eca:ECA2047 hypothetical protein YP_003259919.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; chitin synthase; KEGG: eca:ECA2046 bifunctional enzyme including aminotransferase and chitin synthase YP_003259920.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: eca:ECA2045 NAD dependent epimerase/dehydratase YP_003259921.1 PFAM: transglycosylase; KEGG: pct:PC1_2247 transglycosylase YP_003259922.1 PFAM: YheO domain protein; KEGG: eca:ECA2041 DNA-binding protein YP_003259923.1 catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine YP_003259924.1 PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: eca:ECA2039 ornithine cyclodeaminase YP_003259925.1 PFAM: alanine racemase domain protein; KEGG: eca:ECA2038 hypothetical protein YP_003259926.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: pct:PC1_2254 MarR family transcriptional regulator YP_003259927.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pct:PC1_2255 hypothetical protein YP_003259928.1 KEGG: eca:ECA2034 respiratory nitrate reductase 1 gamma chain; TIGRFAM: respiratory nitrate reductase, subunit gamma; PFAM: nitrate reductase subunit gamma YP_003259929.1 KEGG: pct:PC1_2257 nitrate reductase molybdenum cofactor assembly chaperone; TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: nitrate reductase subunit delta YP_003259930.1 TIGRFAM: nitrate reductase subunit beta; KEGG: eca:ECA2032 respiratory nitrate reductase 1 beta chain YP_003259931.1 KEGG: eca:ECA2031 respiratory nitrate reductase 1 alpha chain; TIGRFAM: nitrate reductase subunit alpha; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_003259933.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA2030 nitrite extrusion protein YP_003259934.1 KEGG: eca:ECA2029 nitrate/nitrite sensor protein NarX; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein YP_003259935.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_003259936.1 PFAM: acyltransferase 3; KEGG: eca:ECA2027 acyltransferase YP_003259937.1 KEGG: pct:PC1_2264 hypothetical protein YP_003259938.1 PFAM: cation transport protein ChaC; KEGG: eca:ECA2025 cation transporter YP_003259940.1 PFAM: FAD-binding 9 siderophore-interacting domain protein; Siderophore-interacting protein; KEGG: eca:ECA2023 siderophore-interacting protein YP_003259941.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: eca:ECA2022 calcium/sodium:proton antiporter YP_003259942.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_003259944.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA2018 short chain dehydrogenase YP_003259945.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: dda:Dd703_1789 EAL domain protein YP_003259946.1 KEGG: eca:ECA2014 hypothetical protein YP_003259947.1 response regulator in two-component regulatory system with RstB YP_003259948.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: eca:ECA2012 sensor protein RstB YP_003259949.1 required for growth and survival under moderately acid conditions YP_003259950.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: peptidase S1 and S6 chymotrypsin/Hap; KEGG: eca:ECA2009 exported protease YP_003259952.1 PFAM: EAL domain protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; KEGG: pct:PC1_2286 diguanylate cyclase/phosphodiesterase with GAF sensor YP_003259953.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_003259955.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_003259956.1 KEGG: eca:ECA2004 lipoprotein YP_003259957.1 KEGG: eca:ECA2003 hypothetical protein YP_003259958.1 KEGG: eca:ECA2001 aerotaxis receptor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer YP_003259959.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: pct:PC1_2294 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding YP_003259960.1 PFAM: protein of unknown function DUF333; KEGG: pct:PC1_2295 hypothetical protein YP_003259961.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_003259963.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: pct:PC1_2318 Mg2 transporter protein CorA family protein YP_003259964.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1992 periplasmic murein peptide-binding protein YP_003259965.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: eca:ECA1991 murein peptide amidase A YP_003259966.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_003259967.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_003259968.1 PFAM: peptidase dimerisation domain protein; peptidase M20; KEGG: eca:ECA1988 peptidase YP_003259969.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA1987 hypothetical protein YP_003259970.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: pct:PC1_2327 hypothetical protein YP_003259971.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_003259972.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_003259973.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_003259974.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_003259975.1 PFAM: glycoside hydrolase family 5; type 3a cellulose-binding domain protein; KEGG: eca:ECA1981 endoglucanase V YP_003259976.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1977 peptide transport periplasmic protein YP_003259977.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_2343 binding-protein-dependent transport systems inner membrane component YP_003259978.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1975 peptide transporter permease protein YP_003259979.1 KEGG: eca:ECA1974 peptide transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA YP_003259980.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1973 peptide transporter ATP-binding protein YP_003259981.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_003259982.1 KEGG: csa:Csal_1206 hypothetical protein YP_003259983.1 KEGG: hch:HCH_03994 hypothetical protein YP_003259984.1 KEGG: pct:PC1_2348 hypothetical protein YP_003259985.1 KEGG: pct:PC1_2349 hypothetical protein YP_003259986.1 KEGG: bur:Bcep18194_B3040 hypothetical protein YP_003259987.1 PFAM: ApbE family lipoprotein; KEGG: pct:PC1_2350 ApbE family lipoprotein YP_003259988.1 TIGRFAM: flavocytochrome C; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FMN-binding domain protein; HI0933 family protein; NADH:flavin oxidoreductase/NADH oxidase; KEGG: eca:ECA1969 NADH:flavin oxidoreductase YP_003259989.1 PFAM: glycoside hydrolase family 31; KEGG: eca:ECA1968 glycosyl hydrolase YP_003259990.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1967 hexuronate transporter YP_003259991.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; KEGG: eca:ECA1966 transcriptional repressor YP_003259992.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1965 LysR family transcriptional regulator YP_003259993.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase; KEGG: pct:PC1_2356 oxidoreductase alpha (molybdopterin) subunit YP_003259994.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_003259995.1 PFAM: aldo/keto reductase; KEGG: eca:ECA1962 oxidoreductase YP_003259996.1 PFAM: carbon starvation protein CstA; KEGG: pct:PC1_2361 carbon starvation protein CstA YP_003259997.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_003259998.1 PFAM: glycoside hydrolase family 42 domain protein; beta-galactosidase trimerisation domain protein; KEGG: kpn:KPN_04612 glycoside hydrolase family protein 42 YP_003259999.1 TIGRFAM: oligosaccharide/H+ symporter, major facilitator superfamily (MFS); PFAM: proton/sugar symporter LacY; major facilitator superfamily MFS_1; KEGG: kpe:KPK_5056 oligosaccharide:H+ symporter YP_003260000.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_003260001.1 KEGG: pct:PC1_2363 lipoprotein YP_003260002.1 involved in start site selection during the initiation of translation YP_003260003.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_003260004.1 PFAM: hypothetical protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat; KEGG: pct:PC1_2367 tetratricopeptide TPR_2 repeat protein YP_003260005.1 PFAM: protein of unknown function DUF1049; KEGG: pct:PC1_2368 hypothetical protein YP_003260006.1 PFAM: sugar-binding domain protein; KEGG: eca:ECA1954 transcriptional regulator YP_003260007.1 PFAM: xylose isomerase; KEGG: eca:ECA1953 xylose isomerase YP_003260008.1 PFAM: carbohydrate kinase, FGGY-like; KEGG: eca:ECA1952 glycerol kinase YP_003260009.1 PFAM: transketolase; transketolase central region; KEGG: eca:ECA1951 transketolase C-terminal section YP_003260010.1 PFAM: transketolase; KEGG: eca:ECA1950 transketolase N-terminal section YP_003260011.1 PFAM: inner-membrane translocator; KEGG: eca:ECA1949 sugar ABC transporter permease YP_003260012.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1948 sugar ABC transporter ATP-binding protein YP_003260013.1 PFAM: periplasmic lipoprotein; KEGG: eca:ECA1947 lipoprotein YP_003260014.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB0812 ABC transporter periplasmic sugar binding protein YP_003260015.1 KEGG: pct:PC1_2370 phosphatidylglycerophosphatase; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related YP_003260016.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_003260017.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA1942 periplasmic oligopeptide-binding protein YP_003260018.1 KEGG: ses:SARI_02726 hypothetical protein YP_003260019.1 Catalyzes the conversion of citrate to isocitrate YP_003260020.1 PFAM: sodium:dicarboxylate symporter; KEGG: eca:ECA1939 glutamate symport protein YP_003260022.1 PFAM: glutathione S-transferase domain; KEGG: pct:PC1_2375 glutathione S-transferase YP_003260023.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_003260024.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_003260025.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_003260026.1 PFAM: protein of unknown function DUF2091, periplasmic; KEGG: pct:PC1_2379 lipoprotein YP_003260027.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_003260028.1 PFAM: 17 kDa surface antigen; KEGG: eca:ECA1932 outer membrane lipoprotein YP_003260029.1 transcription regulator that can both activate or repress expression YP_003260030.1 PFAM: protein of unknown function DUF1289; KEGG: pct:PC1_2383 hypothetical protein YP_003260031.1 KEGG: eca:ECA1929 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase YP_003260032.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_003260033.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: eca:ECA1927 hypothetical protein YP_003260034.1 PFAM: NLP/P60 protein; KEGG: eca:ECA1926 hypothetical protein YP_003260035.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_003260036.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_003260037.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_003260038.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_003260039.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: eca:ECA1921 L-lactate permease YP_003260040.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: eca:ECA1920 hypothetical protein YP_003260041.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; KEGG: eca:ECA1919 electron transporter YP_003260042.1 PFAM: protein of unknown function DUF162; KEGG: eca:ECA1918 hypothetical protein YP_003260043.1 KEGG: eca:ECA1917 allophanate hydrolase; TIGRFAM: urea carboxylase; urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; allophanate hydrolase subunit 1; biotin/lipoyl attachment domain-containing protein; carbamoyl-phosphate synthetase large chain domain protein; SMART: allophanate hydrolase subunit 2; allophanate hydrolase subunit 1 YP_003260044.1 KEGG: pct:PC1_2394 hypothetical protein YP_003260045.1 TIGRFAM: urea carboxylase-associated protein 1; PFAM: Domain of unknown function DUF1989; KEGG: eca:ECA1916 hypothetical protein YP_003260046.1 TIGRFAM: urea carboxylase-associated protein 2; PFAM: Domain of unknown function DUF1989; KEGG: pct:PC1_2396 UreA carboxylase-associated protein 2 YP_003260047.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1914 ABC transporter ATP-binding protein YP_003260048.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1913 ABC transporter permease YP_003260049.1 TIGRFAM: ABC transporter periplasmic protein, urea carboxylase region; KEGG: eca:ECA1912 ABC transporter periplasmic protein YP_003260050.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: eca:ECA1911 MarR family transcriptional regulator YP_003260051.1 KEGG: eca:ECA1910 hypothetical protein YP_003260052.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: eca:ECA1909 catalase-peroxidase YP_003260053.1 PFAM: protein of unknown function DUF1528; transposase IS3/IS911 family protein; KEGG: dze:Dd1591_0425 relaxase YP_003260054.1 PFAM: sigma-54 factor interaction domain-containing protein; SMART: ATPase AAA; KEGG: dze:Dd1591_0424 sigma 54 interacting domain protein YP_003260055.1 KEGG: spc:Sputcn32_2884 hypothetical protein YP_003260056.1 TIGRFAM: hypothetical protein; PFAM: PAAR repeat-containing protein; hypothetical protein; KEGG: eca:ECA2869 rhs protein YP_003260057.1 PFAM: Domain of unknown function DUF1795; KEGG: eca:ECA4277 hypothetical protein YP_003260058.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: eca:ECA2867 rhs accessory genetic element YP_003260059.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: pct:PC1_0054 type VI secretion system effector, Hcp1 family YP_003260060.1 KEGG: hde:HDEF_1764 transcriptional activator of maltose metabolism YP_003260061.1 KEGG: net:Neut_0006 phage integrase YP_003260062.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: eca:ECA3947 D-isomer specific 2-hydroxyacid dehydrogenase YP_003260063.1 KEGG: pct:PC1_3739 hypothetical protein YP_003260064.1 PFAM: protein of unknown function DUF2207, membrane; KEGG: pct:PC1_3740 hypothetical protein YP_003260065.1 PFAM: LemA family protein; KEGG: pct:PC1_3741 LemA family protein YP_003260066.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: pct:PC1_3745 major facilitator superfamily MFS_1 YP_003260067.1 KEGG: pct:PC1_3749 hypothetical protein YP_003260068.1 KEGG: sea:SeAg_B2063 hypothetical protein YP_003260069.1 KEGG: shw:Sputw3181_3748 hypothetical protein YP_003260070.1 KEGG: spc:Sputcn32_1424 hypothetical protein YP_003260071.1 KEGG: hch:HCH_03872 hypothetical protein YP_003260072.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_003260073.1 KEGG: eca:ECA1900 nitrate/nitrite sensor protein NarQ; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein YP_003260074.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA1898 ferredoxin-type protein YP_003260075.1 PFAM: NapD family protein; KEGG: pct:PC1_2410 NapD family protein YP_003260076.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_003260077.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_003260078.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_003260079.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_003260080.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_003260081.1 KEGG: eca:ECA1890 cytochrome C biogenesis protein; TIGRFAM: cytochrome C biogenesis protein CcmI; PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide repeat YP_003260082.1 PFAM: cytochrome C biogenesis protein; KEGG: eca:ECA1889 cytochrome C biogenesis protein YP_003260083.1 TIGRFAM: periplasmic protein thiol/disulphide oxidoreductase DsbE; PFAM: redoxin; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; KEGG: pct:PC1_2418 periplasmic protein thiol/disulphide oxidoreductase DsbE YP_003260084.1 TIGRFAM: cytochrome C biogenesis protein CcmF; PFAM: cytochrome C assembly protein; KEGG: eca:ECA1887 cytochrome C biogenesis protein YP_003260085.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome C maturation system; periplasmic protein anchored to the inner membrane YP_003260086.1 TIGRFAM: heme exporter protein CcmD; PFAM: Heme exporter protein D (CcmD); KEGG: pct:PC1_2421 heme exporter protein CcmD YP_003260087.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome C assembly protein; KEGG: pct:PC1_2422 heme exporter protein CcmC YP_003260088.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: eca:ECA1883 heme exporter protein B YP_003260089.1 ATP-binding protein; required for proper cytochrome C maturation YP_003260090.1 KEGG: eca:ECA1881 formate-dependent nitrite reductase complex subunit NrfG YP_003260091.1 TIGRFAM: cytochrome C nitrite reductase, accessory protein NrfF; PFAM: cytochrome C biogenesis protein; KEGG: eca:ECA1880 formate-dependent nitrite reductase complex subunit NrfF YP_003260092.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome C552 YP_003260093.1 TIGRFAM: cytochrome C nitrite reductase, NrfD subunit; PFAM: polysulphide reductase NrfD; KEGG: eca:ECA1878 nitrite reductase complex component YP_003260094.1 TIGRFAM: cytochrome C nitrite reductase, Fe-S protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pct:PC1_2430 cytochrome C nitrite reductase, Fe-S protein YP_003260095.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_003260096.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_003260098.1 PFAM: inosine/uridine-preferring nucleoside hydrolase; KEGG: eca:ECA1874 inosine-uridine preferring nucleoside hydrolase YP_003260099.1 PFAM: glycoside hydrolase family 13 domain protein; esterase; KEGG: eca:ECA1873 glycosyl hydrolase exoenzyme YP_003260100.1 KEGG: pat:Patl_0833 hypothetical protein YP_003260101.1 PFAM: porin; KEGG: dze:Dd1591_1706 porin YP_003260102.1 PFAM: glycoside hydrolase family 1; KEGG: eca:ECA1871 6-phospho-beta-glucosidase YP_003260103.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003260104.1 PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: pct:PC1_2440 transcriptional antiterminator, BglG YP_003260105.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003260106.1 PFAM: LPP repeat-containing protein; KEGG: pct:PC1_2442 LPP repeat-containing protein YP_003260107.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: eca:ECA1865 hypothetical protein YP_003260108.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_003260109.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_003260110.1 with SufBC activates cysteine desulfurase SufS YP_003260111.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_003260112.1 with SufCD activates cysteine desulfurase SufS YP_003260113.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_003260114.1 KEGG: pct:PC1_2451 hypothetical protein YP_003260115.1 PFAM: thioesterase superfamily protein; KEGG: eca:ECA1857 hypothetical protein YP_003260116.1 PFAM: FAD linked oxidase; KEGG: eca:ECA1856 FAD-binding oxidase YP_003260117.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_003260118.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_003260119.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003260120.1 PFAM: protein of unknown function DUF299; KEGG: eca:ECA1852 hypothetical protein YP_003260121.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_003260122.1 PFAM: Haemin-degrading family protein; KEGG: pct:PC1_2459 hemin-degrading family protein YP_003260123.1 PFAM: periplasmic binding protein; KEGG: eca:ECA1845 hemin-binding periplasmic protein YP_003260124.1 PFAM: transporter permease; KEGG: eca:ECA1844 hemin transporter permease YP_003260125.1 with HmuTU is involved in the transport of hemin YP_003260126.1 PFAM: protein of unknown function UPF0061; KEGG: eca:ECA1842 hypothetical protein YP_003260127.1 PFAM: EAL domain protein; KEGG: eca:ECA1841 hypothetical protein YP_003260128.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: eca:ECA1840 high-affinity gluconate transporter YP_003260129.1 KEGG: eca:ECA1839 gluconokinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase YP_003260130.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: eca:ECA1838 gluconate utilization system Gnt-I transcriptional repressor YP_003260131.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_003260132.1 PFAM: NLP/P60 protein; KEGG: eca:ECA1835 lipoprotein YP_003260133.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_003260134.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_003260135.1 with BtuD and BtuF transports vitamin B12 into the cell YP_003260136.1 PFAM: methyltransferase type 11; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: eca:ECA1831 methyltransferase YP_003260137.1 PFAM: cupin; KEGG: eca:ECA1830 hypothetical protein YP_003260138.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; KEGG: eca:ECA1829 Crp/Fnr family transcriptional regulator YP_003260139.1 KEGG: eca:ECA3326 hypothetical protein YP_003260140.1 KEGG: eca:ECA1828 hypothetical protein YP_003260141.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_003260142.1 PFAM: ROK family protein; KEGG: eca:ECA1826 hypothetical protein YP_003260143.1 part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_003260144.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_003260145.1 part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_003260146.1 KEGG: eca:ECA1821 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: TRCF domain protein; transcription factor CarD; helicase; DEAD/DEAH box helicase; type III restriction protein res subunit; SMART: DEAD/DEAH box helicase ; helicase YP_003260147.1 KEGG: eca:ECA1820 chaperone YP_003260148.1 PFAM: regulatory protein TetR; KEGG: eca:ECA1819 TetR family transcriptional regulator YP_003260149.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1818 transporter YP_003260150.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1817 transporter YP_003260151.1 PFAM: 17 kDa surface antigen; KEGG: eca:ECA1816 hypothetical protein YP_003260152.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pct:PC1_2486 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_003260153.1 PFAM: protein of unknown function UPF0227; KEGG: eca:ECA1814 hypothetical protein YP_003260154.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_003260155.1 KEGG: pct:PC1_2489 thiamine kinase; TIGRFAM: thiamine kinase; PFAM: aminoglycoside phosphotransferase YP_003260156.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: pct:PC1_2490 membrane lipoprotein lipid attachment site YP_003260157.1 PFAM: protein of unknown function DUF1425; KEGG: eca:ECA1810 lipoprotein YP_003260158.1 PFAM: histidine triad (HIT) protein; KEGG: eca:ECA1809 purine nucleoside phosphoramidase YP_003260159.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003260160.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: eca:ECA1804 metallodependent hydrolase YP_003260161.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the subunit beta on the DNA YP_003260162.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_003260163.1 PFAM: aminodeoxychorismate lyase; KEGG: pct:PC1_2499 aminodeoxychorismate lyase YP_003260164.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_003260165.1 PFAM: periplasmic binding protein; KEGG: ccv:CCV52592_1611 periplasmic binding protein YP_003260166.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_003260167.1 carries the fatty acid chain in fatty acid biosynthesis YP_003260168.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_003260169.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: eca:ECA1796 acyl carrier protein S-malonyltransferase YP_003260170.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_003260171.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_003260172.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_003260173.1 PFAM: protein of unknown function DUF177; KEGG: pct:PC1_2508 hypothetical protein YP_003260174.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_003260175.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_003260176.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_003260177.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: eca:ECA1788 hypothetical protein YP_003260178.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_003260179.1 PFAM: DinI family protein; KEGG: pct:PC1_2514 DinI family protein YP_003260180.1 KEGG: eca:ECA1785 hypothetical protein YP_003260181.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_003260182.1 PFAM: cytochrome B561; KEGG: eca:ECA1783 hypothetical protein YP_003260183.1 PFAM: YceI family protein; KEGG: pct:PC1_2518 YceI family protein YP_003260184.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: eca:ECA1781 hypothetical protein YP_003260185.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: eca:ECA1780 NADH-dependent flavin oxidoreductase YP_003260186.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_003260187.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_003260188.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_003260189.1 KEGG: eca:ECA1776 hypothetical protein YP_003260190.1 PFAM: PepSY-associated TM helix domain protein; KEGG: pct:PC1_2525 PepSY-associated TM helix domain protein YP_003260191.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_2526 methyl-accepting chemotaxis sensory transducer YP_003260192.1 KEGG: eca:ECA1773 hypothetical protein YP_003260193.1 KEGG: pct:PC1_2529 hypothetical protein YP_003260194.1 PFAM: protein of unknown function DUF2566; KEGG: eca:ECA1771 hypothetical protein YP_003260195.1 PFAM: protein of unknown function DUF523; KEGG: eca:ECA1770 hypothetical protein YP_003260196.1 PFAM: UspA domain protein; KEGG: eca:ECA1769 hypothetical protein YP_003260197.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_2533 GCN5-related N-acetyltransferase YP_003260198.1 PFAM: isochorismatase hydrolase; KEGG: pct:PC1_2534 isochorismatase hydrolase YP_003260199.1 PFAM: NUDIX hydrolase; KEGG: eca:ECA1766 hypothetical protein YP_003260200.1 KEGG: pct:PC1_2536 hypothetical protein YP_003260201.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: eca:ECA1665 DNA-binding protein Hns YP_003260202.1 PFAM: colicin immunity protein/pyocin immunity protein; KEGG: ses:SARI_02581 hypothetical protein YP_003260203.1 PFAM: transposase IS3/IS911 family protein; KEGG: ppg:PputGB1_5424 transposase IS3/IS911 family protein YP_003260204.1 KEGG: ent:Ent638_1886 hypothetical protein YP_003260205.1 PFAM: protein of unknown function UPF0005; KEGG: pct:PC1_2537 hypothetical protein YP_003260206.1 TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; KEGG: eca:ECA1762 hypothetical protein YP_003260207.1 PFAM: acylphosphatase; KEGG: eca:ECA1761 acylphosphatase YP_003260208.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: pct:PC1_2540 hemimethylated DNA binding protein YP_003260209.1 PFAM: CoA-binding protein; KEGG: pct:PC1_2541 CoA-binding protein YP_003260210.1 PFAM: protein of unknown function DUF2057; KEGG: eca:ECA1758 hypothetical protein YP_003260211.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_003260212.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_003260213.1 PFAM: protein of unknown function DUF307; KEGG: eca:ECA1755 hypothetical protein YP_003260214.1 TIGRFAM: hypothetical protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: pct:PC1_2546 hypothetical protein YP_003260215.1 PFAM: TfoX domain protein; KEGG: pct:PC1_2547 regulator of competence-specific genes YP_003260216.1 PFAM: cell division inhibitor SulA; KEGG: pct:PC1_2548 cell division inhibitor SulA YP_003260217.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_003260218.1 PFAM: protein of unknown function DUF1047; KEGG: eca:ECA1750 hypothetical protein YP_003260219.1 KEGG: pct:PC1_2551 hypothetical protein YP_003260220.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_003260221.1 PFAM: protein of unknown function DUF533; KEGG: eca:ECA1747 hypothetical protein YP_003260222.1 PFAM: ribose/galactose isomerase; KEGG: pct:PC1_2558 ribose/galactose isomerase YP_003260223.1 KEGG: eca:ECA1674 hypothetical protein YP_003260224.1 KEGG: pct:PC1_1466 hypothetical protein YP_003260225.1 PFAM: protein of unknown function DUF2058; KEGG: eca:ECA1578 hypothetical protein YP_003260226.1 PFAM: Cold-shock protein DNA-binding; KEGG: eca:ECA1580 cold-shock protein YP_003260227.1 KEGG: hypothetical protein YP_003260228.1 KEGG: eca:ECA2760 hypothetical protein YP_003260229.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: eca:ECA2761 hypothetical protein YP_003260230.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: eca:ECA2762 hypothetical protein YP_003260231.1 PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_1589 major facilitator superfamily MFS_1 YP_003260232.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_003260233.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA2765 threonine and homoserine efflux system YP_003260234.1 KEGG: eca:ECA2766 hypothetical protein YP_003260235.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_003260236.1 similar to periplasmic-binding component of ABC transporters YP_003260237.1 similar to permease of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_003260238.1 similar to ATP-binding protein of ABC transporters YP_003260239.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: eca:ECA2771 peptidase YP_003260240.1 PFAM: glycosyl transferase, family 3-like; KEGG: eca:ECA2772 glycosyl transferase YP_003260242.1 KEGG: eca:ECA3741 bacteriophage tail fiber protein YP_003260243.1 TIGRFAM: phage tail protein I; PFAM: tail protein I; KEGG: pct:PC1_1576 phage tail protein I YP_003260244.1 PFAM: Baseplate J family protein; KEGG: pct:PC1_1575 baseplate J family protein YP_003260245.1 PFAM: GPW/gp25 family protein; KEGG: pct:PC1_1574 gpW/GP25 family protein YP_003260246.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: pct:PC1_1573 phage baseplate assembly protein V YP_003260247.1 PFAM: late control D family protein; KEGG: pct:PC1_1572 late control D family protein YP_003260248.1 PFAM: tail X family protein; KEGG: pct:PC1_1571 tail X family protein YP_003260249.1 PFAM: P2 GpU family protein; KEGG: pct:PC1_1570 P2 GpU family protein YP_003260250.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: pct:PC1_1569 phage tail tape measure protein, TP901 family YP_003260251.1 KEGG: see:SNSL254_A4551 hypothetical protein YP_003260252.1 KEGG: pct:PC1_1568 hypothetical protein YP_003260253.1 TIGRFAM: phage major tail tube protein; PFAM: major tail tube protein; KEGG: pct:PC1_1566 phage major tail tube protein YP_003260254.1 PFAM: tail sheath protein; KEGG: pct:PC1_1565 tail sheath protein YP_003260255.1 KEGG: pct:PC1_1564 hypothetical protein YP_003260256.1 PFAM: protein of unknown function Gp37; KEGG: pct:PC1_1563 hypothetical protein YP_003260257.1 KEGG: eca:ECA2776 hypothetical protein YP_003260258.1 KEGG: eca:ECA2777 hypothetical protein YP_003260259.1 KEGG: pct:PC1_1560 hypothetical protein YP_003260260.1 PFAM: lytic transglycosylase catalytic; KEGG: eca:ECA2779 transglycosylase YP_003260261.1 KEGG: pct:PC1_1558 hypothetical protein YP_003260262.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: pct:PC1_1557 type I secretion outer membrane protein, TolC family YP_003260263.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: hypothetical protein; KEGG: eca:ECA2782 protease hypothetical protein YP_003260264.1 KEGG: eca:ECA2783 protease secretion ATP-binding protein; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: ATPase AAA YP_003260265.1 PFAM: metalloprotease inhibitor I38; KEGG: eca:ECA2784 protease inhibitor YP_003260266.1 KEGG: pct:PC1_1553 serralysin; PFAM: peptidase M10 serralysin ; Hemolysin-type calcium-binding region; peptidase M10A and M12B matrixin and adamalysin; SMART: peptidase metallopeptidase YP_003260267.1 helicase involved in DNA repair and perhaps also replication YP_003260268.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA2787 AraC family transcription regulator YP_003260269.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA2788 LysE family translocator YP_003260270.1 KEGG: pct:PC1_1549 hypothetical protein YP_003260271.1 KEGG: eca:ECA2789 isopentenyl-diphosphate delta-isomerase; TIGRFAM: isopentenyl-diphosphate delta-isomerase; PFAM: NUDIX hydrolase YP_003260272.1 PFAM: glycoside hydrolase; KEGG: eca:ECA2790 periplasmic beta-glucosidase YP_003260273.1 PFAM: aminotransferase class-III; KEGG: pct:PC1_1546 aminotransferase class-III YP_003260274.1 PFAM: extracellular solute-binding protein family 1; KEGG: pct:PC1_1545 extracellular solute-binding protein family 1 YP_003260275.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: pct:PC1_1544 ABC transporter YP_003260276.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1543 binding-protein-dependent transport systems inner membrane component YP_003260277.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: pct:PC1_1542 DeoR family transcriptional regulator YP_003260278.1 PFAM: glutathione S-transferase domain; KEGG: eca:ECA2791 glutathione S-transferase YP_003260279.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_003260280.1 PFAM: FMN-binding domain protein; KEGG: eca:ECA2794 hypothetical protein YP_003260281.1 TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: eca:ECA2795 adenylate cyclase YP_003260282.1 KEGG: eca:ECA2796 hypothetical protein YP_003260283.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines YP_003260284.1 PFAM: amino acid permease-associated region; KEGG: pct:PC1_1534 amino acid permease-associated region YP_003260285.1 PFAM: dihydrouridine synthase; KEGG: eca:ECA2799 tRNA-dihydrouridine synthase C YP_003260286.1 PFAM: protein of unknown function DUF208; KEGG: eca:ECA2800 hypothetical protein YP_003260287.1 PFAM: extracellular solute-binding protein family 5; KEGG: pct:PC1_1531 extracellular solute-binding protein family 5 YP_003260288.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_003260289.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: dda:Dd703_2413 AraC family transcriptional regulator YP_003260290.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: dda:Dd703_2418 protein of unknown function DUF6 transmembrane YP_003260291.1 this helicase is not essential cell growth YP_003260292.1 KEGG: pct:PC1_1527 hypothetical protein YP_003260293.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_1526 ABC transporter YP_003260294.1 PFAM: transporter permease; KEGG: pct:PC1_1525 transporter permease YP_003260295.1 PFAM: transporter permease; KEGG: eca:ECA2808 achromobactin transporter permease YP_003260296.1 PFAM: periplasmic binding protein; KEGG: eca:ECA2809 achromobactin-binding periplasmic protein YP_003260297.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pct:PC1_1522 TonB-dependent receptor YP_003260298.1 PFAM: hypothetical protein; KEGG: pct:PC1_1521 hypothetical protein YP_003260299.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_1520 ABC transporter YP_003260300.1 PFAM: ABC transporter; KEGG: pct:PC1_1519 ABC-2 type transporter YP_003260301.1 PFAM: ABC transporter; KEGG: pct:PC1_1518 ABC-2 type transporter YP_003260303.1 PFAM: protein of unknown function UPF0005; KEGG: pct:PC1_1517 hypothetical protein YP_003260304.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_003260305.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_003260306.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_003260307.1 TIGRFAM: molybdenum cofactor biosynthesis protein B; molybdenum cofactor synthesis protein; PFAM: molybdopterin binding domain; KEGG: eca:ECA2816 molybdenum cofactor biosynthesis protein B YP_003260308.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_003260309.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: eca:ECA2818 hypothetical protein YP_003260310.1 KEGG: hypothetical protein YP_003260311.1 KEGG: eca:ECA2819 hypothetical protein YP_003260312.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-subunit beta is inserted between the strands, where it probes for the presence of a lesion YP_003260313.1 KEGG: spe:Spro_0389 hypothetical protein YP_003260314.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_003260315.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: methyltransferase type 11; tellurite resistance methyltransferase, TehB, core; methyltransferase type 12; KEGG: pct:PC1_1507 biotin biosynthesis protein BioC YP_003260316.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_003260317.1 KEGG: eca:ECA2825 biotin synthase; TIGRFAM: biotin synthase; PFAM: biotin and thiamin synthesis associated; radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_003260318.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_003260319.1 PFAM: glycoside hydrolase family 12; KEGG: pct:PC1_1503 cellulase YP_003260320.1 PFAM: LrgA family protein; KEGG: pct:PC1_1498 LrgA family protein YP_003260321.1 PFAM: LrgB family protein; KEGG: pct:PC1_1497 LrgB family protein YP_003260322.1 KEGG: pct:PC1_1496 hypothetical protein YP_003260323.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_003260324.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_003260325.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1493 binding-protein-dependent transport systems inner membrane component YP_003260326.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1492 binding-protein-dependent transport systems inner membrane component YP_003260327.1 PFAM: extracellular solute-binding protein family 5; KEGG: eca:ECA2834 ABC transporter periplasmic protein YP_003260328.1 KEGG: eca:ECA2835 ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA YP_003260329.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_003260330.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_003260331.1 PFAM: nitroreductase; KEGG: eca:ECA2838 hypothetical protein YP_003260332.1 KEGG: eca:ECA2840 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003260333.1 PFAM: protein of unknown function UPF0057; KEGG: eca:ECA2844 hypothetical protein YP_003260334.1 TIGRFAM: TonB-dependent copper receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: eca:ECA2845 TonB dependent receptor YP_003260335.1 KEGG: eca:ECA2846 hypothetical protein YP_003260336.1 KEGG: dze:Dd1591_2165 hypothetical protein YP_003260337.1 KEGG: bav:BAV2779 lipoprotein YP_003260339.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: eca:ECA1475 hypothetical protein YP_003260340.1 PFAM: protein of unknown function DUF1971; KEGG: pct:PC1_1354 hypothetical protein YP_003260341.1 PFAM: Domain of unknown function DUF1869; KEGG: pct:PC1_1353 domain of unknown function DUF1869 YP_003260342.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA1470 ABC transporter substrate binding protein YP_003260343.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1469 ABC transporter permease YP_003260344.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_1344 ABC transporter YP_003260346.1 PFAM: Zeta toxin family protein; KEGG: shn:Shewana3_1822 zeta toxin family protein YP_003260347.1 PFAM: myo-inositol catabolism IolB domain protein; KEGG: eca:ECA1465 hypothetical protein YP_003260348.1 PFAM: xylose isomerase; KEGG: pct:PC1_1342 myo-inosose-2 dehydratase YP_003260349.1 PFAM: protein of unknown function DUF2090; PfkB domain protein; KEGG: eca:ECA1463 carbohydrate kinase YP_003260350.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: pct:PC1_1340 oxidoreductase domain protein YP_003260351.1 PFAM: inner-membrane translocator; KEGG: eca:ECA1461 sugar ABC transporter permease YP_003260352.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA1460 sugar ABC transporter ATP-binding protein YP_003260353.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: eca:ECA1459 sugar ABC transporter periplasmic protein YP_003260354.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: eca:ECA1458 myo-inositol 2-dehydrogenase YP_003260355.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: eca:ECA1457 thiamine pyrophosphate-dependent protein YP_003260356.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: eca:ECA1456 aldehyde dehydrogenase YP_003260357.1 PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: pct:PC1_1333 RpiR family transcriptional regulator YP_003260358.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: eca:ECA1454 hypothetical protein YP_003260359.1 PFAM: extracellular solute-binding protein family 1; KEGG: pct:PC1_1331 extracellular solute-binding protein family 1 YP_003260360.1 KEGG: eca:ECA1453 signaling membrane protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; MASE2 domain protein; SMART: GGDEF domain containing protein YP_003260361.1 PFAM: peptidase S53 propeptide; peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: eca:ECA1450 protease YP_003260362.1 catalyzes the interconversion of chorismate to prephenate YP_003260363.1 PFAM: protein of unknown function DUF940 membrane lipoprotein KEGG: eca:ECA1448 hypothetical protein YP_003260364.1 PFAM: protein of unknown function DUF1017; KEGG: pct:PC1_1323 hypothetical protein YP_003260365.1 KEGG: pct:PC1_1322 lipoprotein YP_003260366.1 KEGG: pct:PC1_1321 hypothetical protein YP_003260367.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_003260368.1 PFAM: nucleotidyl transferase; KEGG: eca:ECA1443 UTP--glucose-1-phosphate uridylyltransferase YP_003260369.1 KEGG: eca:ECA1442 glucose-1-phosphate thymidylyltransferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase YP_003260370.1 KEGG: eca:ECA1441 dTDP-6-deoxy-D-glucose-3,5 epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_003260371.1 TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; polysaccharide biosynthesis protein CapD; 3-beta hydroxysteroid dehydrogenase/isomerase; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA1440 dTDP-4-dehydrorhamnose reductase YP_003260372.1 KEGG: kpu:KP1_3695 UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase-like YP_003260373.1 KEGG: asu:Asuc_0818 hypothetical protein YP_003260374.1 KEGG: cko:CKO_00752 hypothetical protein YP_003260375.1 PFAM: glycosyl transferase family 2; KEGG: dps:DP0013 glycosyltransferase involved capsular polysaccharide biosynthesis YP_003260376.1 PFAM: glycosyl transferase group 1; KEGG: pay:PAU_00363 lipopolysaccharide 1,6-galactosyltransferase YP_003260377.1 PFAM: glycosyltransferase family 52; KEGG: abm:ABSDF0075 polysaccharide biosynthesis protein YP_003260378.1 PFAM: polysaccharide biosynthesis protein; KEGG: pmu:PM0507 hypothetical protein YP_003260379.1 KEGG: aeh:Mlg_2327 N-acetylneuraminate synthase; TIGRFAM: pseudaminic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein YP_003260380.1 TIGRFAM: pseudaminic acid biosynthesis N-acetyl transferase; PFAM: GCN5-related N-acetyltransferase; KEGG: abc:ACICU_00079 acetyltransferase YP_003260381.1 TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG; KEGG: aeh:Mlg_2325 polysaccharide biosynthesis protein YP_003260382.1 TIGRFAM: pseudaminic acid CMP-transferase; PFAM: acylneuraminate cytidylyltransferase; KEGG: aeh:Mlg_2324 acylneuraminate cytidylyltransferase YP_003260383.1 TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: par:Psyc_0654 DegT/DnrJ/EryC1/StrS aminotransferase YP_003260384.1 TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase; PFAM: polysaccharide biosynthesis protein CapD; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; NAD-dependent epimerase/dehydratase; KEGG: bpt:Bpet2302 sugar nucleotide epimerase / oxidoreductase YP_003260385.1 KEGG: eca:ECA1420 undecaprenyl-phosphate galactosephosphotransferase; TIGRFAM: undecaprenyl-phosphate galactose phosphotransferase, WbaP; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase YP_003260386.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_003260387.1 PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; KEGG: pct:PC1_1297 protein tyrosine phosphatase YP_003260388.1 PFAM: polysaccharide export protein; Soluble ligand binding domain; KEGG: eca:ECA1417 polysaccharide export protein YP_003260389.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase, family 4, conserved region; KEGG: pct:PC1_1295 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_003260390.1 PFAM: integral membrane protein TerC; transporter-associated region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: eca:ECA1415 hypothetical protein YP_003260391.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_003260392.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_003260393.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_003260394.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_003260395.1 PFAM: ATPase-like, ParA/MinD; KEGG: pct:PC1_1288 ATPase YP_003260396.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_003260397.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: eca:ECA1408 formate dehydrogenase, nitrate-inducible, major subunit YP_003260398.1 TIGRFAM: formate dehydrogenase subunit beta; PFAM: formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: eca:ECA1407 formate dehydrogenase, nitrate-inducible, iron-sulfur subunit YP_003260399.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_003260400.1 KEGG: pct:PC1_1283 hypothetical protein YP_003260401.1 KEGG: pct:PC1_1282 hypothetical protein YP_003260402.1 KEGG: pct:PC1_1281 hypothetical protein YP_003260403.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_003260404.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: eca:ECA1665 DNA-binding protein Hns YP_003260405.1 KEGG: gur:Gura_2880 hypothetical protein YP_003260406.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_003260407.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_003260408.1 PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: eca:ECA1400 nucleoside H+ symporter YP_003260409.1 PFAM: xylose isomerase; AP endonuclease 2 domain protein; KEGG: eca:ECA1399 hypothetical protein YP_003260410.1 PFAM: oxidoreductase domain protein; semialdehyde dehydrogenase NAD - binding; homoserine dehydrogenase NAD-binding; oxidoreductase domain; KEGG: eca:ECA1398 oxidoreductase YP_003260411.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: pct:PC1_1273 LacI family transcriptional regulator YP_003260412.1 PFAM: xylose isomerase; KEGG: eca:ECA1396 hypothetical protein YP_003260413.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_003260414.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_003260415.1 with ModCB is involved in the high-affinity transport of molybdate YP_003260416.1 KEGG: pct:PC1_1268 hypothetical protein YP_003260417.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_003260418.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_003260419.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: pct:PC1_1265 UDP-glucose 4-epimerase YP_003260420.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_003260421.1 KEGG: pct:PC1_1263 hypothetical protein YP_003260422.1 KEGG: eca:ECA1386 hypothetical protein YP_003260423.1 PFAM: outer membrane efflux protein; KEGG: eca:ECA1385 hypothetical protein YP_003260424.1 TIGRFAM: efflux transporter RND family, MFP subunit; KEGG: eca:ECA1384 copper efflux system protein YP_003260425.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: eca:ECA1383 cation efflux system protein YP_003260426.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_003260427.1 PFAM: NAD(P)H dehydrogenase (quinone); DoxX family protein; KEGG: ara:Arad_7382 (acyl-carrier-protein) phosphodiesterase protein YP_003260428.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_003260429.1 involved in zinc efflux across the cytoplasmic membrane YP_003260430.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: eca:ECA1379 nicotinamide mononucleotide transporter YP_003260431.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_003260432.1 KEGG: eca:ECA1377 hypothetical protein YP_003260433.1 PFAM: protein of unknown function DUF554; KEGG: pct:PC1_1252 hypothetical protein YP_003260434.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_003260435.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: pct:PC1_1250 peptidoglycan-associated lipoprotein YP_003260436.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_003260437.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_003260438.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_003260439.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_003260440.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_003260441.1 TIGRFAM: cyd operon protein YbgE; PFAM: Cyd operon protein YbgE; KEGG: eca:ECA1368 hypothetical protein YP_003260442.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: eca:ECA1367 hypothetical protein YP_003260443.1 TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: pct:PC1_1242 cytochrome d ubiquinol oxidase subunit II YP_003260444.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: pct:PC1_1241 cytochrome bd ubiquinol oxidase subunit I YP_003260445.1 PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; KEGG: pct:PC1_1240 hypothetical protein YP_003260446.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_003260447.1 catalyzes the interconversion of succinyl-CoA and succinate YP_003260448.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_003260449.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_003260450.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_003260451.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_003260452.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: pct:PC1_1233 succinate dehydrogenase, hydrophobic membrane anchor protein YP_003260453.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: pct:PC1_1232 succinate dehydrogenase, cytochrome b556 subunit YP_003260454.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_003260455.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_003260456.1 KEGG: pct:PC1_1229 pyrrolidone-carboxylate peptidase; TIGRFAM: pyrrolidone-carboxylate peptidase; PFAM: peptidase C15 pyroglutamyl peptidase I YP_003260457.1 PFAM: LamB/YcsF family protein; KEGG: eca:ECA1353 LamB/YcsF family protein YP_003260458.1 KEGG: eca:ECA1352 allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; SMART: allophanate hydrolase subunit 2 YP_003260459.1 PFAM: allophanate hydrolase subunit 1; SMART: allophanate hydrolase subunit 1; KEGG: eca:ECA1351 allophanate hydrolase subunit 1 YP_003260460.1 PFAM: protein of unknown function DUF34; KEGG: eca:ECA1350 hydrolase-oxidase YP_003260461.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_003260462.1 PFAM: protein of unknown function DUF1722; protein of unknown function DUF523; KEGG: pct:PC1_1223 hypothetical protein YP_003260463.1 PFAM: protein of unknown function DUF2517; KEGG: eca:ECA1344 hypothetical protein YP_003260464.1 KEGG: bbt:BBta_3107 hypothetical protein YP_003260465.1 KEGG: plu:plu0351 hypothetical protein YP_003260466.1 PFAM: transcriptional regulator; KEGG: eca:ECA1338 DNA-binding transcriptional activator KdpE YP_003260467.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pct:PC1_1213 hypothetical protein YP_003260468.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_003260469.1 negative modulator of the initiation of chromosome replication YP_003260470.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: pct:PC1_1210 alpha/beta hydrolase YP_003260471.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: eca:ECA1333 LexA regulated protein YP_003260472.1 PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: pct:PC1_1208 methyl-accepting chemotaxis sensory transducer YP_003260473.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_003260474.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_003260475.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003260476.1 TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: pct:PC1_1204 PTS system, N-acetylglucosamine-specific IIBC subunit YP_003260477.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_003260478.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_003260479.1 PFAM: ROK family protein; KEGG: pct:PC1_1201 ROK family protein YP_003260480.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_003260481.1 KEGG: pct:PC1_1199 hypothetical protein YP_003260482.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_003260483.1 KEGG: pct:PC1_1197 tRNA-i(6)A37 thiotransferase enzyme MiaB; TIGRFAM: tRNA-i(6)A37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family; PFAM: protein of unknown function UPF0004 ; radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB YP_003260484.1 PFAM: PhoH family protein; KEGG: pct:PC1_1196 PhoH family protein YP_003260485.1 PFAM: protein of unknown function UPF0054; KEGG: pct:PC1_1195 hypothetical protein YP_003260486.1 PFAM: transporter-associated region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: pct:PC1_1194 transporter-associated region YP_003260487.1 transfers the fatty acyl group on membrane lipoproteins YP_003260488.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: pct:PC1_1192 extracellular solute-binding protein family 3 YP_003260489.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA1313 glutamate/aspartate transporter permease protein YP_003260490.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_1190 polar amino acid ABC transporter inner membrane protein YP_003260491.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_1189 ABC transporter YP_003260492.1 PFAM: protein of unknown function DUF1451; KEGG: pct:PC1_1188 hypothetical protein YP_003260493.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_003260494.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_003260495.1 required for the assembly and function of the DNAX complex which is required for the assembly of the subunit beta onto primed DNA YP_003260496.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_003260497.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: eca:ECA1305 hypothetical protein YP_003260498.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_003260499.1 KEGG: eca:ECA1303 penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain YP_003260500.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: eca:ECA1302 cell wall shape-determining protein YP_003260501.1 TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A; sporulation domain protein; KEGG: pct:PC1_1179 lipoprotein A YP_003260502.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_003260503.1 PFAM: protein of unknown function DUF493; KEGG: pct:PC1_1177 hypothetical protein YP_003260504.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system protein H YP_003260505.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_003260506.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_003260507.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: eca:ECA1295 hypothetical protein YP_003260508.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_003260509.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: eca:ECA1293 aspartate/glutamate racemase YP_003260510.1 PFAM: arsenate reductase; KEGG: eca:ECA1292 hypothetical protein YP_003260511.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_003260512.1 PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: pct:PC1_1168 peptidase M15B and M15C dd-carboxypeptidase VanY/endolysin YP_003260513.1 KEGG: eca:ECA1289 hypothetical protein YP_003260514.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1288 LysR family transcriptional regulator YP_003260515.1 TIGRFAM: citrate/H+ symporter, CitMHS family; PFAM: citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: eca:ECA1287 Mg(2+)/citrate complex transporter YP_003260516.1 PFAM: protein of unknown function DUF1446; KEGG: eca:ECA1286 hypothetical protein YP_003260517.1 KEGG: eca:ECA1285 hypothetical protein YP_003260518.1 KEGG: pct:PC1_1162 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha; PFAM: coenzyme A transferase YP_003260519.1 KEGG: eca:ECA1283 acetate CoA-transferase beta subunit; TIGRFAM: 3-oxoacid CoA-transferase subunit beta; PFAM: coenzyme A transferase YP_003260520.1 KEGG: pct:PC1_1160 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase YP_003260521.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1281 methyl-accepting chemotaxis protein YP_003260522.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_003260523.1 PFAM: protein of unknown function DUF1272; KEGG: pct:PC1_1157 hypothetical protein YP_003260524.1 PFAM: protein of unknown function DUF699 ATPase ; GCN5-related N-acetyltransferase; KEGG: eca:ECA1266 acetyltransferase YP_003260525.1 PFAM: protein of unknown function DUF441; KEGG: eca:ECA1265 hypothetical protein YP_003260526.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_003260527.1 PFAM: NlpBDapX family lipoprotein; KEGG: eca:ECA1263 lipoprotein YP_003260528.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_003260529.1 negative transcriptional regulator of the gcvTHP operon YP_003260530.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_003260531.1 PFAM: peptidase M48 Ste24p; KEGG: eca:ECA1259 hypothetical protein YP_003260532.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: eca:ECA1258 arsenate reductase YP_003260533.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_003260534.1 TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: pct:PC1_1131 uracil-xanthine permease YP_003260535.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_003260536.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_003260537.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_003260538.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: vcj:VCD_000696 hypothetical protein YP_003260539.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_1125 diamine N-acetyltransferase YP_003260540.1 PFAM: protein of unknown function DUF214; KEGG: eca:ECA1224 hypothetical protein YP_003260541.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_1123 ABC transporter YP_003260542.1 PFAM: lipolytic protein G-D-S-L family; KEGG: eca:ECA1222 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 YP_003260543.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pct:PC1_1121 short-chain dehydrogenase/reductase SDR YP_003260544.1 PFAM: thioredoxin domain; KEGG: eca:ECA1220 thioredoxin YP_003260545.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: pct:PC1_1119 competence/damage-inducible protein CinA YP_003260546.1 TIGRFAM: aromatic amino acid transporter; PFAM: tryptophan/tyrosine permease; Amino acid transporter transmembrane; KEGG: pct:PC1_1118 aromatic amino acid transporter YP_003260547.1 PFAM: YfaZ family protein; KEGG: eca:ECA1217 hypothetical protein YP_003260548.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA1215 O-succinylbenzoic acid--CoA ligase YP_003260549.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_003260550.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_003260551.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_003260552.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_003260553.1 TIGRFAM: isochorismate synthase; PFAM: chorismate binding-like; KEGG: eca:ECA1210 menaquinone-specific isochorismate synthase YP_003260554.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: eca:ECA1207 short chain dehydrogenase YP_003260555.1 PFAM: helix-turn-helix HxlR type; regulatory protein MarR; KEGG: eca:ECA1206 transcriptional regulator YP_003260556.1 PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_1109 major facilitator superfamily MFS_1 YP_003260557.1 KEGG: eca:ECA1204 phosphotransfer intermediate protein in two-component regulatory system with RcsBC; PFAM: Hpt domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein YP_003260558.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_003260559.1 PFAM: Signal transduction histidine kinase RcsC, alpha-beta loop-like; ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: pct:PC1_1106 histidine kinase YP_003260560.1 negatively supercoils closed circular double-stranded DNA YP_003260561.1 Involved in ubiquinone biosynthesis YP_003260562.1 Catalyzes the rate-limiting step in dNTP synthesis YP_003260563.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_003260564.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_003260565.1 PFAM: band 7 protein; SMART: band 7 protein; KEGG: eca:ECA1196 hypothetical protein YP_003260566.1 PFAM: protein of unknown function DUF107; KEGG: pct:PC1_1099 hypothetical protein YP_003260567.1 KEGG: eca:ECA1194 copper efflux regulator; TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR YP_003260568.1 KEGG: abm:ABSDF1448 hypothetical protein YP_003260569.1 TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; haloacid dehalogenase type 3; KEGG: eca:ECA1193 copper exporting ATPase YP_003260570.1 PFAM: GumN family protein; KEGG: pct:PC1_1094 GumN family protein YP_003260571.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: eca:ECA1191 hypothetical protein YP_003260572.1 PFAM: glycoside hydrolase family 28; KEGG: eca:ECA1190 polygalacturonase YP_003260573.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: eca:ECA1189 GTP-binding protein YjiA YP_003260574.1 PFAM: protein of unknown function DUF466; KEGG: pct:PC1_1090 hypothetical protein YP_003260575.1 PFAM: carbon starvation protein CstA; KEGG: eca:ECA1187 carbon starvation protein YP_003260576.1 KEGG: eca:ECA1185 hypothetical protein YP_003260577.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_003260578.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_003260579.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_003260580.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_003260581.1 molecular chaperone YP_003260582.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_003260583.1 PFAM: conserved hypothetical protein; KEGG: pct:PC1_1077 hypothetical protein YP_003260584.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_003260585.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_003260586.1 PFAM: protein of unknown function DUF454; KEGG: eca:ECA1174 hypothetical protein YP_003260587.1 PFAM: Primosomal replication priB and priC; KEGG: pct:PC1_1073 primosomal replication PriB and PriC YP_003260588.1 PFAM: protein of unknown function DUF2496, YbaM-related; KEGG: eca:ECA1172 hypothetical protein YP_003260589.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_003260590.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: hypothetical protein; KEGG: eca:ECA1170 acriflavine resistance protein A YP_003260591.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: pct:PC1_1069 transporter hydrophobe/amphiphile efflux-1 (HAE1) family YP_003260592.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_003260593.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_003260594.1 PFAM: biofilm formation regulator YbaJ; KEGG: pct:PC1_1066 hypothetical protein YP_003260595.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_003260596.1 TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: pct:PC1_1064 methylated-DNA/protein-cysteine methyltransferase YP_003260597.1 KEGG: pct:PC1_1063 lipoprotein YP_003260598.1 TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; KEGG: pct:PC1_1062 acyl-CoA thioesterase II YP_003260599.1 TIGRFAM: ammonium transporter; PFAM: ammonium transporter; KEGG: pct:PC1_1061 ammonium transporter YP_003260600.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_003260601.1 PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; KEGG: pct:PC1_1059 ABC transporter related YP_003260602.1 PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; KEGG: eca:ECA1158 multidrug transporter membrane\ATP-binding proteins YP_003260603.1 PFAM: transcription regulator, AsnC-type-like; SMART: transcription regulator, AsnC-type; KEGG: eca:ECA1157 transcription regulator AsnC YP_003260604.1 KEGG: ecs:ECs4618 hypothetical protein YP_003260605.1 PFAM: pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pct:PC1_1056 pyridoxal-5'-phosphate-dependent protein beta subunit YP_003260606.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_003260607.1 PFAM: thioesterase superfamily protein; KEGG: pct:PC1_1054 thioesterase superfamily protein YP_003260608.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: eca:ECA1153 hypothetical protein YP_003260609.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: pct:PC1_1052 PpiC-type peptidyl-prolyl cis-trans isomerase YP_003260610.1 histone-like DNA-binding protein YP_003260611.1 KEGG: eca:ECA1150 DNA-binding ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16; ATPase AAA; ATPase associated with various cellular activities AAA_5; SMART: peptidase S16; ATPase AAA YP_003260612.1 binds and unfolds substrates as part of the ClpXP protease YP_003260613.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_003260614.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_003260615.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_003260616.1 PFAM: Uncharacterized lipoprotein; KEGG: pct:PC1_1045 uncharacterized lipoprotein YP_003260617.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_003260618.1 TIGRFAM: ubiquinol oxidase subunit II; PFAM: COX aromatic rich domain protein; cytochrome C oxidase subunit II; KEGG: pct:PC1_1043 ubiquinol oxidase subunit II YP_003260619.1 KEGG: eca:ECA1142 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: cytochrome o ubiquinol oxidase subunit I; PFAM: cytochrome C oxidase subunit I YP_003260620.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit III; PFAM: cytochrome C oxidase subunit III; KEGG: eca:ECA1141 cytochrome o ubiquinol oxidase subunit III YP_003260621.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: eca:ECA1140 cytochrome o ubiquinol oxidase subunit IV YP_003260622.1 converts protoheme IX and farnesyl diphosphate to heme O YP_003260623.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA1138 transporter YP_003260624.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_003260625.1 Ketopantoate reductase; catalyzes the NADPH reduction of Ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_003260626.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA1135 hypothetical protein YP_003260627.1 Required for the synthesis of the thiazole moiety YP_003260628.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_003260629.1 PFAM: polyprenyl synthetase; KEGG: pct:PC1_1031 polyprenyl synthetase YP_003260630.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_003260631.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_003260632.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_003260633.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; subunit beta of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_003260634.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_003260635.1 PFAM: ATP-cone domain protein; KEGG: pct:PC1_1024 ATP-cone domain protein YP_003260636.1 KEGG: eca:ECA1124 hypothetical protein YP_003260637.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_003260638.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_003260639.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_003260640.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_003260641.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_003260642.1 PFAM: protein of unknown function DUF479; KEGG: eca:ECA1118 hypothetical protein YP_003260643.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; peroxiredoxin-like; redoxin; KEGG: pct:PC1_1015 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_003260644.1 PFAM: MscS Mechanosensitive ion channel; KEGG: pct:PC1_1014 MscS mechanosensitive ion channel YP_003260645.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_003260646.1 TIGRFAM: branched-chain amino acid transporter II carrier protein; PFAM: branched-chain amino acid transporter II carrier protein; KEGG: eca:ECA1114 branched-chain amino acid transporter II carrier protein YP_003260647.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_003260648.1 TIGRFAM: phosphate binding protein; KEGG: pct:PC1_1010 phosphate binding protein YP_003260649.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_003260650.1 KEGG: pct:PC1_1008 two component transcriptional regulator PhoB, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver YP_003260651.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_003260652.1 TIGRFAM: exonuclease SbcC; PFAM: SMC domain protein; KEGG: eca:ECA1108 exonuclease YP_003260653.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_003260654.1 Required for efficient pilin antigenic variation YP_003260655.1 PFAM: chemotaxis sensory transducer; Cache domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA1105 methyl-accepting chemotaxis protein YP_003260656.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pct:PC1_1002 GntR family transcriptional regulator YP_003260657.1 PFAM: PfkB domain protein; KEGG: pct:PC1_1001 PfkB domain protein YP_003260658.1 PFAM: ADP-ribosylation/crystallin J1; KEGG: pct:PC1_1000 ADP-ribosylation/crystallin J1 YP_003260659.1 TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: pct:PC1_0999 nucleoside transporter YP_003260660.1 PFAM: protein of unknown function DUF1255; KEGG: eca:ECA1104 hypothetical protein YP_003260661.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_003260662.1 KEGG: eca:ECA1102 L-asparaginase precursor; TIGRFAM: L-asparaginase, type II; PFAM: asparaginase/glutaminase YP_003260663.1 efflux pump for the antibacterial peptide microcin J25 YP_003260664.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: pct:PC1_0993 type I secretion outer membrane protein, TolC family YP_003260665.1 KEGG: pct:PC1_0992 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA YP_003260666.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: hypothetical protein; KEGG: eca:ECA1096 type I hypothetical protein YP_003260667.1 PFAM: glycoside hydrolase family 28; KEGG: eca:ECA1095 endo-polygalacturonase YP_003260668.1 PFAM: pectate lyase; KEGG: eca:ECA1094 pectate lyase YP_003260669.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_003260670.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pct:PC1_0986 GntR domain protein YP_003260671.1 KEGG: eca:ECA1090 lipoprotein YP_003260672.1 PFAM: stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: pct:PC1_0984 protein serine/threonine phosphatase YP_003260673.1 KEGG: eca:ECA1088 hypothetical protein YP_003260674.1 PFAM: Domain of unknown function DUF1987; KEGG: eca:ECA1087 lipoprotein YP_003260675.1 KEGG: eca:ECA1086 signaling protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003260676.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA1085 LysR family transcriptional regulator YP_003260677.1 PFAM: protein of unknown function DUF81; KEGG: pct:PC1_0979 hypothetical protein YP_003260679.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_003260680.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: pct:PC1_0976 alkylphosphonate utilization operon protein PhnA YP_003260681.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: eca:ECA1081 transcriptional regulator YP_003260682.1 This protein performs the mismatch recognition step during the DNA repair process YP_003260683.1 PFAM: copper resistance lipoprotein NlpE; KEGG: pct:PC1_0963 copper resistance lipoprotein NlpE YP_003260684.1 PFAM: YaeQ family protein; KEGG: eca:ECA1051 hypothetical protein YP_003260685.1 PFAM: protein of unknown function UPF0253; KEGG: pct:PC1_0961 hypothetical protein YP_003260686.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_003260687.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_003260688.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: eca:ECA1048 hypothetical protein YP_003260689.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_003260690.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_003260691.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_003260692.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_003260693.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_003260694.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_003260695.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_003260696.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: eca:ECA1040 periplasmic chaperone YP_003260697.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_003260698.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_003260699.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_003260700.1 KEGG: pct:PC1_0946 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_003260701.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_003260702.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_003260703.1 Catalyzes the phosphorylation of UMP to UDP YP_003260704.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_003260705.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_003260706.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_003260707.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_003260708.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_003260709.1 KEGG: eca:ECA1027 hypothetical protein YP_003260710.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_003260711.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_003260712.1 PFAM: protein of unknown function DUF446; KEGG: pct:PC1_0934 hypothetical protein YP_003260714.1 PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: eca:ECA1023 MarR family transcriptional regulator YP_003260715.1 PFAM: amidohydrolase; amidohydrolase; KEGG: eca:ECA1022 exoenzyme regulatory protein YP_003260716.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_003260717.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_003260718.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA1019 lysine decarboxylase family protein YP_003260719.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_003260720.1 KEGG: eca:ECA1017 RNA 2'-O-ribose methyltransferase YP_003260721.1 PFAM: protein of unknown function DUF423; KEGG: pct:PC1_0928 hypothetical protein YP_003260722.1 glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_003260723.1 PFAM: protein of unknown function DUF903; KEGG: eca:ECA1013 lipoprotein YP_003260724.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: eca:ECA1012 cysteine sulfinate desulfinase YP_003260725.1 TIGRFAM: cysteine desulfurase, sulfur acceptor subunit CsdE; PFAM: Fe-S metabolism associated SufE; KEGG: pct:PC1_0924 cysteine desulfurase, sulfur acceptor subunit CsdE YP_003260726.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: eca:ECA1010 hypothetical protein YP_003260727.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: eca:ECA1009 biotin sulfoxide reductase YP_003260728.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_003260729.1 KEGG: eca:ECA1000 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin YP_003260730.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_003260731.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0998 mandelate racemase YP_003260732.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA0997 LacI family transcriptional regulator YP_003260733.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_003260734.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_003260735.1 PFAM: peptidase M16 domain protein; KEGG: eca:ECA0994 protease III precursor YP_003260736.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_003260737.1 KEGG: eca:ECA0992 prepilin peptidase dependent protein c precursor YP_003260738.1 PFAM: protein of unknown function DUF2509; KEGG: eca:ECA0991 hypothetical protein YP_003260739.1 KEGG: eca:ECA0990 hypothetical protein YP_003260740.1 KEGG: pct:PC1_0908 hypothetical protein YP_003260741.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_003260742.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_003260743.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_003260744.1 hydrolyzes diadenosine polyphosphate YP_003260745.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_003260746.1 PFAM: protein of unknown function DUF903; KEGG: pct:PC1_0900 hypothetical protein YP_003260748.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_003260749.1 KEGG: pct:PC1_0885 hypothetical protein YP_003260750.1 PFAM: protein of unknown function DUF469; KEGG: eca:ECA0978 hypothetical protein YP_003260751.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_003260752.1 KEGG: eca:ECA0976 adenine DNA glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; iron-sulfur cluster loop; SMART: HhH-GPD family protein; iron-sulfur cluster loop YP_003260753.1 PFAM: Fe(II) trafficking protein YggX; KEGG: pct:PC1_0881 Fe(II) trafficking protein YggX YP_003260754.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_003260755.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA0973 AraC family transcription regulator YP_003260756.1 KEGG: eca:ECA0972 hypothetical protein YP_003260757.1 KEGG: plu:plu3955 hypothetical protein YP_003260758.1 PFAM: TIM-barrel signal transduction protein; KEGG: eca:ECA0971 hypothetical protein YP_003260759.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA0970 hypothetical protein YP_003260760.1 PFAM: regulatory protein TetR; KEGG: eca:ECA0969 TetR family transcriptional regulator YP_003260761.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pct:PC1_0874 short-chain dehydrogenase/reductase SDR YP_003260762.1 PFAM: amino acid permease-associated region; KEGG: pct:PC1_0873 amino acid permease-associated region YP_003260763.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: eca:ECA0967 ornithine decarboxylase YP_003260764.1 PFAM: integrase; KEGG: dze:Dd1591_3537 integrase YP_003260765.1 KEGG: eci:UTI89_C0293 hypothetical protein YP_003260766.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: eci:UTI89_C0292 transcription regulator YP_003260767.1 KEGG: eci:UTI89_C0291 hypothetical protein YP_003260768.1 PFAM: Resolvase domain; KEGG: eci:UTI89_C0290 resolvase YP_003260769.1 KEGG: bbr:BB4149 hypothetical protein YP_003260770.1 KEGG: bbr:BB4148 hypothetical protein YP_003260772.1 PFAM: integrase; KEGG: eci:UTI89_C0286 integrase YP_003260773.1 PFAM: multicopper oxidase type 3; multicopper oxidase type 2; KEGG: avi:Avi_1253 polyphenol oxidase protein YP_003260774.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_003260775.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_003260776.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_003260777.1 PFAM: ankyrin; SMART: ankyrin; KEGG: pct:PC1_3286 ankyrin YP_003260778.1 PFAM: ankyrin; KEGG: pct:PC1_3287 ankyrin YP_003260779.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_003260780.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_003260781.1 KEGG: pct:PC1_3290 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20 YP_003260782.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_003260783.1 SMART: hypothetical protein; KEGG: eca:ECA3469 DNA-binding protein YP_003260784.1 PFAM: methyltransferase type 11; methyltransferase small; UbiE/COQ5 methyltransferase; methyltransferase type 12; KEGG: eca:ECA3470 methyltransferase YP_003260785.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: pct:PC1_3294 ErfK/YbiS/YcfS/YnhG family protein YP_003260786.1 PFAM: glutamine amidotransferase class-II; KEGG: pct:PC1_3295 glutamine amidotransferase class-II YP_003260787.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_003260788.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_003260789.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: eca:ECA3475 hypothetical protein YP_003260790.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_003260791.1 KEGG: pct:PC1_3300 translation initiation factor, aIF-2BI family; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related YP_003260792.1 PFAM: PAAR repeat-containing protein; KEGG: pct:PC1_2184 PaaR repeat-containing protein YP_003260793.1 KEGG: pct:PC1_2185 hypothetical protein YP_003260794.1 KEGG: pct:PC1_2185 hypothetical protein YP_003260795.1 KEGG: pct:PC1_2185 hypothetical protein YP_003260796.1 KEGG: pct:PC1_2186 hypothetical protein YP_003260797.1 KEGG: pct:PC1_2187 hypothetical protein YP_003260798.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; Gp5 domain protein; KEGG: pct:PC1_2188 type VI secretion system Vgr family protein YP_003260799.1 PFAM: acireductone dioxygenase; KEGG: eca:ECA3485 oxidase YP_003260800.1 KEGG: pct:PC1_3302 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase YP_003260801.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_003260802.1 catalyzes the transfer of an amino moiety YP_003260803.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pct:PC1_3305 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_003260804.1 KEGG: dps:DP3026 pyruvate formate-lyase activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: radical SAM domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_003260805.1 PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; KEGG: dde:Dde_1273 formate C-acetyltransferase YP_003260806.1 KEGG: pfs:PFLU5857 aliphatic sulfonatesABC transporter, substrate-binding protein; TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; PFAM: substrate-binding region of ABC-type glycine betaine transporter; SMART: extracellular solute-binding protein family 3 YP_003260807.1 PFAM: aminotransferase class-III; KEGG: atc:AGR_L_2984 probable pyridoxal-dependent aminotransferase YP_003260808.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_003260809.1 PFAM: aminotransferase class V; KEGG: eca:ECA3491 purine catabolism protein YP_003260810.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3492 amino acid ABC transporter ATP-binding protein YP_003260811.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3493 amino acid ABC transporter permease protein YP_003260812.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3494 amino acid ABC transporter permease protein YP_003260813.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA3495 amino acid ABC transporter substrate binding protein YP_003260814.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: eca:ECA3496 transcriptional regulator YP_003260815.1 PFAM: gamma-glutamyltranspeptidase; KEGG: eca:ECA3497 gamma-glutamyltranspeptidase YP_003260816.1 KEGG: eca:ECA3498 hypothetical protein YP_003260817.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_003260818.1 KEGG: eca:ECA3500 hypothetical protein YP_003260819.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: eca:ECA3501 hypothetical protein YP_003260820.1 KEGG: eca:ECA3502 glycine betaine/L-proline transport ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter ATPase; PFAM: ABC transporter; CBS domain containing protein; SMART: ATPase AAA YP_003260821.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_003260822.1 with ProVW, part of the high-affinity transporter for the osmoprotectant glycine betaine YP_003260823.1 PFAM: alpha/beta hydrolase fold; KEGG: eca:ECA3505 hydrolase YP_003260824.1 PFAM: protein of unknown function DUF1470; KEGG: pct:PC1_3324 hypothetical protein YP_003260825.1 PFAM: Domain of unknown function DUF2394; KEGG: eca:ECA3507 hypothetical protein YP_003260826.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3508 transporter YP_003260827.1 PFAM: AzlC family protein; KEGG: pct:PC1_3327 AzlC family protein YP_003260828.1 PFAM: protein of unknown function DUF2598; KEGG: pct:PC1_3328 hypothetical protein YP_003260829.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_003260830.1 TIGRFAM: efflux pump membrane protein; PFAM: hypothetical protein family protein; KEGG: eca:ECA3512 multidrug resistance protein A YP_003260831.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3513 multidrug resistance protein B YP_003260832.1 KEGG: eca:ECA3515 lipoprotein YP_003260833.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: eca:ECA3516 methyltransferase YP_003260834.1 TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: pct:PC1_3335 thioredoxin YP_003260835.1 PFAM: DTW domain containing protein; KEGG: eca:ECA3518 hypothetical protein YP_003260836.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: pct:PC1_3337 GCN5-related N-acetyltransferase YP_003260837.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_003260838.1 KEGG: pct:PC1_3339 hypothetical protein YP_003260839.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: pct:PC1_3340 metabolite/H+ symporter, major facilitator superfamily (MFS) YP_003260841.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_003260842.1 part of the metNIQ transporter for methionine YP_003260843.1 part of the MetNIQ methionine uptake system YP_003260844.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: pct:PC1_3344 lipoprotein, YaeC family YP_003260845.1 KEGG: eca:ECA3527 outer membrane lipoprotein YP_003260846.1 PFAM: protein of unknown function UPF0066; KEGG: eca:ECA3528 hypothetical protein YP_003260847.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_003260848.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_003260849.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_003260850.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_003260851.1 catalyzes the modification of U13 in tRNA(Glu) YP_003260852.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_003260853.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_003260854.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_003260855.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: pct:PC1_3355 extracellular solute-binding protein family 3 YP_003260856.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3538 amino acid ABC transporter YP_003260857.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3539 amino acid ABC transporter ATP-binding protein YP_003260858.1 KEGG: pct:PC1_3358 hypothetical protein YP_003260859.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_003260860.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_003260861.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_003260862.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Sirohaem synthase, dimerisation domain; KEGG: pct:PC1_3362 uroporphyrin-III C-methyltransferase YP_003260863.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: pct:PC1_1952 PTS IIA-like nitrogen-regulatory protein PtsN YP_003260864.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: vsa:VSAL_I0704 PTS system, cellobiose-specific component IIB YP_003260865.1 KEGG: vvy:VV2900 phosphotransferase system cellobiose-specific component IIC; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC YP_003260866.1 PFAM: glycoside hydrolase family 1; KEGG: spe:Spro_4221 beta-glucosidase YP_003260867.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: vfm:VFMJ11_0622 HTH-type transcriptional regulator AscG YP_003260868.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_003260869.1 hemoprotein; NADPH dependent; with the subunit alpha (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_003260870.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_003260871.1 PFAM: type IV pilus assembly PilZ; KEGG: eca:ECA3548 hypothetical protein YP_003260872.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: pct:PC1_3367 diguanylate phosphodiesterase YP_003260873.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: pct:PC1_3372 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_003260874.1 KEGG: pct:PC1_3374 hypothetical protein YP_003260875.1 PFAM: beta-lactamase; KEGG: eca:ECA3555 metallo hydrolase YP_003260876.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: pay:PAU_00969 hypothetical protein YP_003260877.1 PFAM: VRR-NUC domain protein; KEGG: plu:plu1493 hypothetical protein YP_003260878.1 KEGG: pay:PAU_03662 hypothetical protein YP_003260880.1 PFAM: VRR-NUC domain protein; KEGG: plu:plu1493 hypothetical protein YP_003260881.1 KEGG: pay:PAU_03662 hypothetical protein YP_003260882.1 KEGG: pay:PAU_03662 hypothetical protein YP_003260883.1 KEGG: pmr:PMI2995 hypothetical protein YP_003260884.1 PFAM: glycosyl hydrolase family 88; KEGG: eca:ECA3559 plant-inducible protein YP_003260885.1 KEGG: eca:ECA3560 oligogalacturonide transporter YP_003260886.1 PFAM: periplasmic binding protein; KEGG: pct:PC1_3384 periplasmic binding protein YP_003260887.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pct:PC1_3385 TonB-dependent siderophore receptor YP_003260888.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_003260889.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_003260890.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_003260891.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_003260892.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_003260893.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_003260894.1 KEGG: pct:PC1_3392 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase YP_003260896.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_003260897.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_003260898.1 KEGG: eca:ECA3575 glucarate dehydratase; TIGRFAM: glucarate dehydratase; PFAM: mandelate racemase/muconate lactonizing protein YP_003260899.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: pct:PC1_3396 glucarate dehydratase YP_003260900.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA3577 glucarate transporter YP_003260901.1 KEGG: eca:ECA3578 D-galactarate dehydratase; TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase/altronate hydrolase domain protein; SAF domain protein YP_003260902.1 KEGG: eca:ECA3579 methyl-accepting chemotaxis protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer YP_003260903.1 KEGG: eca:ECA3581 hypothetical protein YP_003260904.1 KEGG: eca:ECA3582 hypothetical protein YP_003260905.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_003260906.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_003260907.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_003260908.1 PFAM: adenylate cyclase; KEGG: eca:ECA3586 hypothetical protein YP_003260909.1 SMART: SH3 domain protein; KEGG: eca:ECA3587 signal transduction protein YP_003260910.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_003260911.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_003260912.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_003260913.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_003260914.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3592 methyl-accepting chemotaxis protein YP_003260915.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_003260916.1 PFAM: AIG2 family protein; KEGG: pct:PC1_3414 AIG2 family protein YP_003260917.1 PFAM: protein of unknown function DUF490; KEGG: pct:PC1_3415 hypothetical protein YP_003260918.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: pct:PC1_3416 surface antigen (D15) YP_003260919.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_003260920.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: pct:PC1_3418 hypothetical protein YP_003260921.1 PFAM: protein of unknown function DUF1107; KEGG: pct:PC1_3419 hypothetical protein YP_003260922.1 PFAM: conserved hypothetical protein; KEGG: pct:PC1_3420 hypothetical protein YP_003260923.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_003260924.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_003260925.1 PFAM: flavodoxin/nitric oxide synthase; KEGG: pct:PC1_3424 flavodoxin/nitric oxide synthase YP_003260926.1 PFAM: protein of unknown function DUF2502; KEGG: pct:PC1_3425 hypothetical protein YP_003260927.1 Involved in anaerobic NO protection and iron metabolism YP_003260928.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_003260929.1 KEGG: pct:PC1_3429 hypothetical protein YP_003260930.1 PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: pct:PC1_3430 opacity-associated protein A YP_003260931.1 PFAM: protein of unknown function DUF488; KEGG: pct:PC1_3431 hypothetical protein YP_003260932.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_003260933.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_003260934.1 binds single-stranded DNA at the primosome assembly site YP_003260935.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_003260936.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_003260937.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3615 methyl-accepting chemotaxis protein YP_003260939.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY YP_003260940.1 similar to release factor 1 and 2 YP_003260942.1 PFAM: protein of unknown function DUF350; KEGG: pct:PC1_3442 hypothetical protein YP_003260943.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_3443 methyl-accepting chemotaxis sensory transducer YP_003260944.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_003260945.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_003260946.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_003260947.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_3447 methyl-accepting chemotaxis sensory transducer YP_003260948.1 KEGG: eca:ECA3625 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; hypothetical protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein YP_003260949.1 KEGG: eca:ECA3626 type II/IV secretion system protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: ATPase AAA YP_003260950.1 PFAM: alanine racemase domain protein; KEGG: pct:PC1_3450 alanine racemase domain protein YP_003260951.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_003260952.1 PFAM: protein of unknown function YGGT; KEGG: pct:PC1_3452 hypothetical protein YP_003260953.1 PFAM: protein of unknown function DUF167; KEGG: pct:PC1_3453 hypothetical protein YP_003260954.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_003260955.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_003260956.1 PFAM: phosphoglycerate mutase; KEGG: ent:Ent638_2024 phosphoglycerate mutase YP_003260957.1 PFAM: entericidin EcnAB; KEGG: eca:ECA3638 entericidin A precursor YP_003260958.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3639 acyltransferase YP_003260959.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA3640 lysophospholipid transporter LplT YP_003260960.1 transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_003260961.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_3464 methyl-accepting chemotaxis sensory transducer YP_003260962.1 PFAM: GCN5-related N-acetyltransferase; KEGG: eca:ECA3643 GnaT-family acetyltransferase YP_003260963.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: pct:PC1_3471 LacI family transcriptional regulator YP_003260964.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_003260965.1 KEGG: kpn:KPN_02369 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta YP_003260966.1 KEGG: vfi:VF_2157 glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase YP_003260967.1 PFAM: gluconate transporter; citrate transporter; KEGG: ypg:YpAngola_A4082 gluconate:H+ symporter (GntP) family protein YP_003260968.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_003260969.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_003260970.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pct:PC1_3488 LysR family transcriptional regulator YP_003260971.1 PFAM: beta-lactamase; KEGG: eca:ECA3655 hypothetical protein YP_003260972.1 KEGG: eca:ECA3656 hypothetical protein YP_003260973.1 KEGG: eca:ECA3657 hypothetical protein YP_003260974.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase; KEGG: eca:ECA3660 tRNA-dihydrouridine synthase A YP_003260975.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_003260977.1 PFAM: cytochrome P450; KEGG: eca:ECA3662 cytochrome YP_003260978.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: eca:ECA3663 quinone oxidoreductase, NADPH-dependent YP_003260979.1 unwinds double stranded DNA YP_003260980.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_003260981.1 KEGG: eca:ECA3666 hypothetical protein YP_003260982.1 PFAM: transcription regulator, AsnC-type-like; SMART: transcription regulator, AsnC-type; KEGG: pct:PC1_3502 transcriptional regulator, AsnC family YP_003260983.1 PFAM: protein of unknown function DUF161; KEGG: eca:ECA3669 hypothetical protein YP_003260984.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_003260985.1 PFAM: protein of unknown function DUF45; KEGG: eca:ECA3671 hypothetical protein YP_003260986.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: pct:PC1_3506 type VI secretion system effector, Hcp1 family YP_003260987.1 PFAM: protein of unknown function DUF1240; KEGG: ypn:YPN_1051 hypothetical protein YP_003260988.1 PFAM: protein of unknown function DUF1240; KEGG: pct:PC1_3507 hypothetical protein YP_003260989.1 PFAM: protein of unknown function DUF1240; KEGG: eca:ECA3674 hypothetical protein YP_003260990.1 PFAM: protein of unknown function DUF1240; KEGG: pct:PC1_3508 hypothetical protein YP_003260991.1 PFAM: protein of unknown function DUF1240; KEGG: pct:PC1_3507 hypothetical protein YP_003260992.1 PFAM: protein of unknown function DUF1240; KEGG: yps:YPTB1065 hypothetical protein YP_003260993.1 PFAM: protein of unknown function DUF1240; KEGG: ypn:YPN_1051 hypothetical protein YP_003260994.1 PFAM: protein of unknown function DUF1240; KEGG: ypn:YPN_1051 hypothetical protein YP_003260995.1 KEGG: eca:ECA3675 hypothetical protein YP_003260996.1 TIGRFAM: CRISPR-associated protein, Csy4 family; PFAM: CRISPR-associated protein Csy4; KEGG: eca:ECA3684 hypothetical protein YP_003260997.1 TIGRFAM: CRISPR-associated protein, Csy3 family; PFAM: CRISPR-associated protein Csy3; KEGG: eca:ECA3683 hypothetical protein YP_003260998.1 TIGRFAM: CRISPR-associated protein, Csy2 family; PFAM: CRISPR-associated protein Csy2; KEGG: eca:ECA3682 hypothetical protein YP_003260999.1 TIGRFAM: CRISPR-associated protein, Csy1 family; PFAM: CRISPR-associated protein Csy1; KEGG: eca:ECA3681 hypothetical protein YP_003261000.1 TIGRFAM: CRISPR-associated helicase Cas3 family; KEGG: eca:ECA3680 hypothetical protein YP_003261001.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; KEGG: eca:ECA3679 hypothetical protein YP_003261002.1 PFAM: protein of unknown function UPF0047; KEGG: eca:ECA3688 hypothetical protein YP_003261003.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrsubunit betas scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_003261004.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_003261005.1 PFAM: amidohydrolase; amidohydrolase; KEGG: pct:PC1_3513 amidohydrolase 3 YP_003261006.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_3514 GCN5-related N-acetyltransferase YP_003261007.1 KEGG: pct:PC1_3515 hypothetical protein YP_003261008.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: pct:PC1_3517 alkylhydroperoxidase like protein, AhpD family YP_003261009.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_3518 GCN5-related N-acetyltransferase YP_003261010.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: pct:PC1_3519 GntR family transcriptional regulator YP_003261011.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: eca:ECA3745 LacI family transcriptional regulator YP_003261012.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA3746 ABC transporter membrane spanning protein YP_003261013.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_3522 binding-protein-dependent transport systems inner membrane component YP_003261014.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: eca:ECA3748 ABC transporter ATP-binding protein YP_003261015.1 PFAM: glycosyl hydrolase family 88; KEGG: eca:ECA3749 plant-inducible protein YP_003261016.1 KEGG: eca:ECA3750 hypothetical protein YP_003261017.1 PFAM: extracellular solute-binding protein family 1; KEGG: eca:ECA3751 extracellular solute-binding protein YP_003261018.1 KEGG: eca:ECA3752 hypothetical protein YP_003261019.1 PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: pct:PC1_3528 ATPase BadF/BadG/BcrA/BcrD type YP_003261020.1 PFAM: metallophosphoesterase; KEGG: eca:ECA3754 calcineurin-like phosphoesterase YP_003261021.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA3756 ABC transporter ATP-binding protein YP_003261022.1 PFAM: ABC transporter; KEGG: eca:ECA3757 ABC transporter membrane protein YP_003261023.1 PFAM: periplasmic solute binding protein; KEGG: pct:PC1_3532 periplasmic solute binding protein YP_003261024.1 KEGG: ypb:YPTS_3652 kinase YP_003261025.1 KEGG: ypi:YpsIP31758_0504 hypothetical protein YP_003261026.1 PFAM: von Willebrand factor A; SMART: von Willebrand factor A; KEGG: ypi:YpsIP31758_0505 tellurium resistance protein YP_003261027.1 PFAM: von Willebrand factor A; SMART: von Willebrand factor A; KEGG: ypy:YPK_0568 von Willebrand factor A YP_003261028.1 PFAM: stress protein; KEGG: ypi:YpsIP31758_0507 tellurium resistance protein YP_003261029.1 PFAM: von Willebrand factor A; SMART: von Willebrand factor A; KEGG: ypb:YPTS_3647 von Willebrand factor A YP_003261030.1 KEGG: ecs:ECs1343 TerW YP_003261031.1 KEGG: ecs:ECs1345 hypothetical protein YP_003261032.1 KEGG: kpe:KPK_A0206 hypothetical protein YP_003261033.1 KEGG: kpe:KPK_A0205 hypothetical protein YP_003261034.1 KEGG: ecs:ECs1349 hypothetical protein YP_003261035.1 PFAM: protein of unknown function DUF201; KEGG: ecv:APECO1_O1R67 hypothetical protein YP_003261036.1 PFAM: stress protein; KEGG: ecs:ECs1351 TerZ YP_003261037.1 PFAM: tellurium resistance; stress protein; KEGG: ece:Z1611 phage inhibition, colicin resistance and tellurite resistance protein YP_003261038.1 PFAM: tellurite resistance TerB; KEGG: kpe:KPK_A0200 tellurite resistance protein TerB YP_003261039.1 PFAM: integral membrane protein TerC; KEGG: ecs:ECs1354 TerC YP_003261040.1 PFAM: stress protein; KEGG: kpe:KPK_A0198 tellurium resistance protein TerD YP_003261041.1 PFAM: stress protein; KEGG: pmr:PMI2383 tellurite resistance protein YP_003261042.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; KEGG: ent:Ent638_3903 HAD family hydrolase YP_003261043.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: eca:ECA3759 DeoR family transcriptional regulator YP_003261044.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: ent:Ent638_0458 regulatory protein, IclR YP_003261045.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: ebw:BWG_3993 KpLE2 phage-like element; transporter YP_003261046.1 KEGG: ent:Ent638_0455 hypothetical protein; TIGRFAM: dehydratase, YjhG/YagF family; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase YP_003261047.1 PFAM: dihydrodipicolinate synthetase; KEGG: ecd:ECDH10B_0255 CP4-6 prophage; lyase/synthase YP_003261048.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_003261049.1 PFAM: type III effector Hrp-dependent outers; KEGG: eca:ECA3761 hypothetical protein YP_003261050.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: pct:PC1_3537 iron-containing alcohol dehydrogenase YP_003261051.1 PFAM: dihydrodipicolinate synthetase; KEGG: pct:PC1_3538 dihydrodipicolinate synthetase YP_003261052.1 PFAM: Na+/solute symporter; KEGG: pct:PC1_3539 Na+/solute symporter YP_003261053.1 KEGG: eca:ECA3765 hypothetical protein YP_003261054.1 PFAM: conserved hypothetical protein; KEGG: pct:PC1_3541 hypothetical protein YP_003261055.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: eca:ECA3767 short-chain dehydrogenase YP_003261056.1 PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; KEGG: eca:ECA3768 formate acetyltransferase YP_003261057.1 KEGG: eca:ECA3769 pyruvate formate-lyase activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: radical SAM protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_003261058.1 PFAM: small multidrug resistance protein; KEGG: eca:ECA3770 quaternary ammonium compound resistance protein YP_003261059.1 PFAM: small multidrug resistance protein; KEGG: eca:ECA3771 multidrug resistance protein YP_003261060.1 TIGRFAM: ribokinase; PFAM: PfkB domain protein; phosphomethylpyrimidine kinase type-1; KEGG: kpu:KP1_2751 ribokinase YP_003261061.1 PFAM: ROK family protein; KEGG: elf:LF82_0079 D-allose kinase YP_003261062.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: kpu:KP1_2752 ribulose-phosphate 3-epimerase YP_003261063.1 PFAM: inner-membrane translocator; KEGG: ypb:YPTS_0834 inner-membrane translocator YP_003261064.1 PFAM: inner-membrane translocator; KEGG: ypb:YPTS_0835 inner-membrane translocator YP_003261065.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ypb:YPTS_0836 ABC transporter YP_003261066.1 KEGG: ypy:YPK_3398 carbohydrate ABC transporter periplasmic-binding protein YP_003261067.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: ypy:YPK_3397 DeoR family transcriptional regulator YP_003261069.1 PFAM: conserved hypothetical protein; KEGG: pct:PC1_3552 hypothetical protein YP_003261070.1 with FepCDG is involved in the transport of ferric enterobactin YP_003261071.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_003261072.1 PFAM: transporter permease; KEGG: dda:Dd703_1497 transporter permease YP_003261073.1 PFAM: transporter permease; KEGG: dda:Dd703_1496 transporter permease YP_003261074.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: dda:Dd703_1495 ABC transporter YP_003261075.1 TIGRFAM: amino acid adenylation protein; non-ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: dze:Dd1591_1322 amino acid adenylation protein YP_003261076.1 PFAM: MbtH domain protein; KEGG: dze:Dd1591_1321 MbtH domain protein YP_003261077.1 PFAM: esterase; KEGG: dda:Dd703_1492 esterase YP_003261078.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: dda:Dd703_1491 TonB-dependent siderophore receptor YP_003261079.1 PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: dda:Dd703_1488 isochorismatase YP_003261080.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_003261081.1 KEGG: eca:ECA3779 hypothetical protein YP_003261082.1 PFAM: protein of unknown function UPF0027; KEGG: pct:PC1_3555 hypothetical protein YP_003261083.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: eca:ECA3780 transcription regulator ArsR YP_003261085.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_003261086.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: pct:PC1_3558 transcriptional regulator, AraC family YP_003261087.1 PFAM: MmgE/PrpD family protein; KEGG: eca:ECA3784 hypothetical protein YP_003261088.1 KEGG: pct:PC1_3560 hypothetical protein YP_003261089.1 PFAM: dienelactone hydrolase; KEGG: pct:PC1_3562 dienelactone hydrolase YP_003261090.1 KEGG: eca:ECA3786 hypothetical protein YP_003261091.1 PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_3563 major facilitator superfamily MFS_1 YP_003261092.1 PFAM: beta-lactamase; KEGG: pct:PC1_3564 beta-lactamase YP_003261093.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pct:PC1_3565 LysR family transcriptional regulator YP_003261094.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_003261095.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_003261096.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_003261097.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_003261098.1 PFAM: amino acid permease-associated region; KEGG: eca:ECA3791 aromatic amino acid transporter YP_003261099.1 involved in regulation of beta-lactamase; signaling protein YP_003261100.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: eca:ECA3795 N-acetyl-anhydromuranmyl-L-alanine amidase YP_003261101.1 PFAM: nucleoside-specific channel-forming protein, Tsx-like; KEGG: pct:PC1_3573 nucleoside-specific channel-forming protein Tsx YP_003261102.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_003261104.1 KEGG: pct:PC1_3575 major pilin subunit YP_003261105.1 PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: eca:ECA3799 hypothetical protein YP_003261106.1 PFAM: type II secretion system F domain; KEGG: eca:ECA3800 type IV pilin biogenesis protein YP_003261107.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_003261109.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_003261110.1 PFAM: protein of unknown function DUF1342; KEGG: pct:PC1_3580 hypothetical protein YP_003261111.1 PFAM: protein of unknown function DUF329; KEGG: pct:PC1_3581 hypothetical protein YP_003261112.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: pct:PC1_3582 mutator MutT protein YP_003261113.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_003261114.1 secM translational pause allows for the initiation of secA translation YP_003261115.1 PFAM: protein of unknown function DUF721; KEGG: eca:ECA3808 hypothetical protein YP_003261116.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_003261117.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_003261118.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_003261119.1 involved in septum formation YP_003261120.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_003261121.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_003261122.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_003261123.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_003261124.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_003261125.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_003261126.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: eca:ECA3819 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_003261127.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_003261128.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: pct:PC1_3598 peptidoglycan glycosyltransferase YP_003261129.1 membrane bound cell division protein at septum containing leucine zipper motif YP_003261130.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: pct:PC1_3600 S-adenosyl-methyltransferase MraW YP_003261131.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_003261132.1 PFAM: protein of unknown function DUF1144; KEGG: eca:ECA3826 hypothetical protein YP_003261133.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_003261134.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_003261135.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_003261136.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA3830 AMP-binding protein YP_003261137.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_003261138.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_003261139.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_003261140.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_003261141.1 PFAM: branched-chain amino acid transport; KEGG: eca:ECA3835 hypothetical protein YP_003261142.1 PFAM: AzlC family protein; KEGG: pct:PC1_3612 AzlC family protein YP_003261143.1 PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA3837 AraC family transcription regulator YP_003261144.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA3838 methyl-accepting chemotaxis protein YP_003261146.1 activates sgrS under glucose-phosphate stress conditions YP_003261147.1 PFAM: NmrA family protein; KEGG: eca:ECA3842 isoflavone oxidoreductase YP_003261148.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA3843 LysR family transcriptional regulator YP_003261149.1 part of the thiamine and TPP transporter tbpA-thiPQ YP_003261150.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_003261151.1 with TbpA and ThiP is part of the thiamine and TPP transporter YP_003261152.1 PFAM: glycoside hydrolase family 43; KEGG: pct:PC1_3622 xylan 1,4-beta-xylosidase YP_003261153.1 PFAM: IlvB leader peptide; KEGG: pct:PC1_3623 hypothetical protein YP_003261154.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: pct:PC1_3624 acetolactate synthase, large subunit, biosynthetic type YP_003261155.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_003261156.1 PFAM: SNARE associated Golgi protein; KEGG: pct:PC1_3626 SNARE associated Golgi protein YP_003261157.1 KEGG: pct:PC1_3627 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003261160.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_003261161.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_003261163.1 KEGG: stm:STM1552 cytoplasmic protein YP_003261165.1 KEGG: stm:STM1552 cytoplasmic protein YP_003261167.1 PFAM: PAAR repeat-containing protein; KEGG: atc:AGR_L_1028 hypothetical protein YP_003261168.1 PFAM: pseudouridine synthase; KEGG: eca:ECA3854 ribosomal large subunit pseudouridine synthase A YP_003261169.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_003261170.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_003261171.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_003261172.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_003261173.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_003261174.1 protein associated with Co2+ and Mg2+ efflux YP_003261175.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_003261176.1 KEGG: pct:PC1_3638 hypothetical protein YP_003261177.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_003261178.1 KEGG: eca:ECA3865 hypothetical protein YP_003261179.1 PFAM: protein of unknown function DUF1212; KEGG: pct:PC1_3643 hypothetical protein YP_003261180.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA3867 LysE-type translocator YP_003261181.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_003261182.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_003261183.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_003261184.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_003261185.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: pct:PC1_3651 peptidylprolyl isomerase FKBP-type YP_003261186.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_003261187.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_003261188.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_003261189.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_003261190.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_003261191.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_003261192.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_003261193.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_003261195.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: eca:ECA3883 hypothetical protein YP_003261196.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: eca:ECA3884 transporter YP_003261197.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_003261198.1 KEGG: pct:PC1_3663 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003261199.1 KEGG: pct:PC1_3664 transaldolase; TIGRFAM: transaldolase; PFAM: transaldolase YP_003261200.1 PFAM: protein of unknown function DUF328; KEGG: pct:PC1_3665 hypothetical protein YP_003261201.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_003261202.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_003261203.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_003261204.1 member of the SPOUT superfamily of methyltransferases YP_003261205.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pct:PC1_3671 transcriptional regulator YP_003261206.1 PFAM: CreA family protein; KEGG: eca:ECA3894 hypothetical protein YP_003261207.1 PFAM: transcription activator effector binding; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA3896 right origin-binding protein YP_003261208.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_003261209.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_003261210.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_003261211.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_003261212.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_003261213.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_3679 methyl-accepting chemotaxis sensory transducer YP_003261214.1 TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES; KEGG: eca:ECA3904 zinc-binding dehydrogenase YP_003261215.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_003261216.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_003261217.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_003261218.1 KEGG: ypi:YpsIP31758_2196 hypothetical protein YP_003261220.1 PFAM: protein of unknown function DUF541; KEGG: pct:PC1_3685 hypothetical protein YP_003261221.1 Involved in the export of arginine YP_003261222.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: pct:PC1_3687 transcriptional regulator, IclR family YP_003261223.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_3688 ABC transporter YP_003261224.1 PFAM: inner-membrane translocator; KEGG: pct:PC1_3689 inner-membrane translocator YP_003261225.1 KEGG: pct:PC1_3690 hypothetical protein YP_003261226.1 PFAM: SMP-30/gluconolaconase/LRE domain protein; KEGG: pct:PC1_3691 gluconolactonase YP_003261227.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate YP_003261228.1 PFAM: conserved hypothetical protein; KEGG: pct:PC1_3693 hypothetical protein YP_003261229.1 PFAM: major facilitator superfamily MFS_1; KEGG: pct:PC1_3694 major facilitator superfamily MFS_1 YP_003261230.1 PFAM: carbohydrate kinase, FGGY-like; KEGG: pct:PC1_3695 carbohydrate kinase FGGY YP_003261231.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_003261232.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_003261233.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_003261234.1 PFAM: MscS Mechanosensitive ion channel; Conserved TM helix repeat-containing protein; KEGG: pct:PC1_3699 MscS mechanosensitive ion channel YP_003261235.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_003261236.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_003261237.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_003261238.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_003261239.1 PFAM: peptidase M48 Ste24p; KEGG: pct:PC1_3704 peptidase M48 Ste24p YP_003261240.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: pct:PC1_3705 LuxR family transcriptional regulator YP_003261241.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_003261243.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_003261244.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: eca:ECA3921 hypothetical protein YP_003261245.1 PFAM: endonuclease I; KEGG: eca:ECA3922 endonuclease YP_003261246.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_003261247.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_003261248.1 PFAM: protein of unknown function DUF179; KEGG: pct:PC1_3712 hypothetical protein YP_003261249.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_003261250.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_003261251.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: eca:ECA3928 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-me so-diaminopimelate ligase YP_003261252.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_003261253.1 PFAM: protein of unknown function DUF2065; KEGG: eca:ECA3930 hypothetical protein YP_003261254.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_003261255.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_003261256.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_003261257.1 Stimulates the elongation of poly(A) tails YP_003261258.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_003261259.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_003261260.1 PFAM: cell wall hydrolase/autolysin; peptidoglycan-binding lysin domain; SMART: cell wall hydrolase/autolysin; peptidoglycan-binding LysM; KEGG: pct:PC1_3724 cell wall hydrolase/autolysin YP_003261261.1 possibly involved in cell wall synthesis YP_003261262.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: eca:ECA3939 hypothetical protein YP_003261263.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pct:PC1_3728 iron-sulfur cluster binding protein YP_003261264.1 TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pct:PC1_3729 alkyl hydroperoxide reductase, F subunit YP_003261265.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_003261266.1 KEGG: eca:ECA3943 hypothetical protein YP_003261267.1 KEGG: psp:PSPPH_0319 autotransporter; TIGRFAM: outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Autotransporter beta- domain protein; phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related YP_003261268.1 KEGG: pct:PC1_1351 hypothetical protein YP_003261269.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_003261270.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_003261271.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_003261272.1 PFAM: MscS Mechanosensitive ion channel; KEGG: eca:ECA3967 hypothetical protein YP_003261273.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003261274.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003261275.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003261276.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003261277.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_003261278.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_003261279.1 PFAM: protein of unknown function DUF486; KEGG: eca:ECA3974 hypothetical protein YP_003261280.1 PFAM: entericidin EcnAB; KEGG: eca:ECA3975 entericidin B YP_003261281.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_003261282.1 KEGG: pct:PC1_3766 lysine 2,3-aminomutase YodO family protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: radical SAM domain protein YP_003261283.1 KEGG: eca:ECA3978 lipoprotein YP_003261284.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_003261285.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_003261286.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; PhoU family protein; KEGG: eca:ECA3983 sodium/phosphate cotransporter YP_003261287.1 TIGRFAM: anion transporter; PFAM: sodium/sulfate symporter; citrate transporter; KEGG: pct:PC1_3771 anion transporter YP_003261288.1 KEGG: lhk:LHK_01568 hypothetical protein YP_003261289.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_003261290.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_003261291.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: pmr:PMI2193 CDP-alcohol phosphatidyltransferase YP_003261292.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: pay:PAU_04266 acyltransferase YP_003261293.1 PFAM: phosphatidate cytidylyltransferase; KEGG: pmr:PMI2195 cytidylyltransferase YP_003261294.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_003261295.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: pct:PC1_3778 isocitrate lyase YP_003261296.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_003261297.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_003261298.1 KEGG: pct:PC1_3781 uncharacterized protein YjaA YP_003261299.1 KEGG: pct:PC1_3782 transferase YP_003261300.1 PFAM: protein of unknown function DUF1488; KEGG: eca:ECA3994 hypothetical protein YP_003261301.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_003261302.1 PFAM: SUA5/yciO/yrdC domain; KEGG: pct:PC1_3785 SUA5/YciO/YrdC domain protein YP_003261303.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: pct:PC1_3786 DNA topoisomerase type IA zn finger domain protein YP_003261304.1 PFAM: protein of unknown function DUF494; KEGG: eca:ECA3997 hypothetical protein YP_003261305.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: pct:PC1_3788 DNA protecting protein DprA YP_003261306.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_003261307.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_003261308.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_003261309.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_003261310.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_003261311.1 PFAM: protein of unknown function DUF331; KEGG: pct:PC1_3794 hypothetical protein YP_003261312.1 is a component of the macrolide binding site in the peptidyl transferase center YP_003261313.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_003261314.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_003261315.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_003261316.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_003261317.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_003261318.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_003261319.1 late assembly protein YP_003261320.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_003261321.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_003261322.1 binds 5S rRNA along with protein L5 and L25 YP_003261323.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_003261324.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_003261325.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_003261326.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_003261327.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_003261328.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_003261329.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_003261330.1 TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: pct:PC1_3814 ribosomal protein L29 YP_003261331.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_003261332.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_003261333.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_003261334.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_003261335.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_003261336.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_003261337.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_003261338.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_003261339.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_003261340.1 KEGG: pct:PC1_3824 hypothetical protein YP_003261341.1 iron storage protein YP_003261342.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: pct:PC1_3826 BFD domain protein (2Fe-2S)-binding domain protein YP_003261343.1 TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain protein; elongation factor Tu domain 2 protein; KEGG: pct:PC1_3827 translation elongation factor Tu YP_003261344.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_003261345.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_003261346.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_003261347.1 TIGRFAM: sulfur relay protein TusB/DsrH; PFAM: DsrH family protein; KEGG: eca:ECA4039 intracellular sulfur oxidation protein YP_003261348.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_003261349.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_003261350.1 PFAM: YheO domain protein; KEGG: pct:PC1_3834 YheO domain protein YP_003261351.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_003261352.1 response regulator in two-component regulatory system with BasS YP_003261353.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: eca:ECA4045 sensor protein BasS/PmrB YP_003261354.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_003261355.1 PFAM: alanine racemase domain protein; KEGG: eca:ECA4047 alanine racemase YP_003261356.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: eca:ECA4048 GntR family transcriptional regulator YP_003261357.1 rotamase YP_003261358.1 PFAM: SlyX family protein; KEGG: eca:ECA4050 hypothetical protein YP_003261359.1 rotamase YP_003261360.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA4055 hypothetical protein YP_003261361.1 involved in potassium efflux YP_003261362.1 required for KefB activity YP_003261363.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_3847 ABC transporter YP_003261364.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA4059 hypothetical protein YP_003261365.1 PFAM: protein of unknown function UPF0270; alpha/beta hydrolase fold; KEGG: eca:ECA4060 hydrolase YP_003261366.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: eca:ECA4062 phosphoribulokinase YP_003261367.1 PFAM: OsmC family protein; KEGG: pct:PC1_3852 OsmC family protein YP_003261368.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_003261369.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_003261370.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_003261371.1 PFAM: pectate lyase/Amb allergen; SMART: pectate lyase/Amb allergen; KEGG: pct:PC1_3858 pectate lyase/Amb allergen YP_003261372.1 PFAM: pectate lyase/Amb allergen; SMART: pectate lyase/Amb allergen; KEGG: pct:PC1_3859 pectate lyase/Amb allergen YP_003261373.1 PFAM: pectate lyase/Amb allergen; SMART: pectate lyase/Amb allergen; KEGG: eca:ECA4069 pectate lyase III YP_003261374.1 KEGG: eca:ECA4070 pectate lyase YP_003261375.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: eca:ECA4071 peptidyl-prolyl cis-trans isomerase A (rotamase A) YP_003261376.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA4072 ABC transporter ATP-binding protein YP_003261377.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_3864 ABC transporter YP_003261378.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4074 ABC transporter permease YP_003261379.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_3866 binding-protein-dependent transport systems inner membrane component YP_003261380.1 PFAM: extracellular solute-binding protein family 5; KEGG: pct:PC1_3867 extracellular solute-binding protein family 5 YP_003261381.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA4077 mandelate racemase / muconate lactonizing enzyme YP_003261382.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: eca:ECA4079 nitrite reductase [NAD(P)H] large subunit YP_003261383.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_003261384.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_003261385.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4082 octopine transporter permease YP_003261386.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4083 octopine transporter permease YP_003261387.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA4084 octopine permease ATP-binding protein P YP_003261388.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4085 octopine-binding periplasmic protein YP_003261389.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: eca:ECA4086 aminobenzoyl-glutamate utilization protein B YP_003261390.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003261391.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_003261392.1 KEGG: pct:PC1_3879 ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase YP_003261393.1 KEGG: pct:PC1_3880 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_003261394.1 PFAM: sporulation domain protein; KEGG: eca:ECA4091 hypothetical protein YP_003261395.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_003261397.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_003261398.1 KEGG: eca:ECA4095 hypothetical protein YP_003261399.1 KEGG: pct:PC1_3886 hypothetical protein YP_003261400.1 PFAM: fimbrial assembly family protein; KEGG: eca:ECA4097 hypothetical protein YP_003261401.1 KEGG: pct:PC1_3888 hypothetical protein YP_003261402.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_003261403.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_003261404.1 PFAM: Intracellular growth attenuator IgaA; KEGG: eca:ECA4102 intracellular growth attenuator protein YP_003261405.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: pct:PC1_3893 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_003261406.1 PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: eca:ECA4104 heat shock protein YP_003261407.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_003261408.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_003261409.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_003261410.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_003261411.1 KEGG: pct:PC1_3899 hypothetical protein YP_003261412.1 PFAM: periplasmic binding protein; KEGG: eca:ECA4110 periplasmic substrate-binding protein YP_003261413.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4111 transporter YP_003261414.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pct:PC1_3905 TonB-dependent siderophore receptor YP_003261415.1 KEGG: pct:PC1_3907 HpcH/HpaI aldolase YP_003261416.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_003261417.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: eca:ECA4119 acyltransferase YP_003261419.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; KEGG: eca:ECA4120 methyl-accepting chemotaxis protein YP_003261420.1 KEGG: pct:PC1_3911 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: citrate synthase YP_003261421.1 PFAM: transcriptional regulator, histidine kinase sensor-like; histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: ecz:ECS88_4665 conserved hypothetical protein with histidine kinase domain YP_003261422.1 PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; KEGG: ecv:APECO1_2301 hypothetical protein YP_003261423.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_003261424.1 PFAM: microcompartments protein; KEGG: ecz:ECS88_4661 conserved hypothetical protein with microcompartments protein domain YP_003261425.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: ssn:SSON_2057 propanediol diffusion facilitator YP_003261426.1 KEGG: ecc:c4538 pyruvate formate-lyase 3 activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: radical SAM protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_003261427.1 KEGG: ecz:ECS88_4672 formate C-acetyltransferase; TIGRFAM: pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical YP_003261428.1 TIGRFAM: intracellular protease PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: ecz:ECS88_4673 conserved hypothetical protein with intracelllular protease 1 domain YP_003261429.1 KEGG: ecz:ECS88_4674 hypothetical protein YP_003261430.1 PFAM: aldehyde dehydrogenase; KEGG: ecz:ECS88_4675 acetaldehyde/propionaldehyde dehydrogenase (EutE-like) YP_003261431.1 PFAM: microcompartments protein; KEGG: ecz:ECS88_4676 propanediol utilization protein, polyhedral bodies (PduB-like) YP_003261432.1 PFAM: microcompartments protein; KEGG: ecz:ECS88_4677 propanediol utilization protein, polyhedral bodies (PduA-like) YP_003261433.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_003261434.1 PFAM: protein of unknown function DUF336; KEGG: ecz:ECS88_4680 hypothetical protein YP_003261435.1 PFAM: ethanolamine utilization protein EutN/carboxysome structural protein Ccml; KEGG: sgl:SG1884 ethanolamine utilization protein EutN YP_003261436.1 KEGG: ecq:ECED1_3451 hypothetical protein YP_003261437.1 PFAM: propanediol utilization protein; KEGG: ecz:ECS88_4684 conserved hypothetical protein involved in propanediol utilization protein (PduL-like) YP_003261438.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: ecq:ECED1_3448 propanol dehydrogenase YP_003261439.1 PFAM: Tex-like protein-like; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: eca:ECA4122 RNA binding protein YP_003261440.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: eca:ECA4123 regulator of exoenzyme YP_003261441.1 transports degraded pectin products into the bacterial cell YP_003261442.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_003261443.1 KEGG: dze:Dd1591_0207 hypothetical protein YP_003261444.1 KEGG: sgl:SG0585 hypothetical protein YP_003261445.1 PFAM: protein of unknown function DUF323; KEGG: dze:Dd1591_0206 protein of unknown function DUF323 YP_003261446.1 PFAM: protein of unknown function DUF214; KEGG: pct:PC1_3917 hypothetical protein YP_003261447.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA4128 ABC transporter ATP-binding protein YP_003261448.1 KEGG: eca:ECA4129 hypothetical protein YP_003261449.1 PFAM: alkaline phosphatase; SMART: alkaline phosphatase; KEGG: eca:ECA4130 alkaline phosphatase YP_003261451.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: eca:ECA4131 aminoglycoside/multidrug efflux system YP_003261452.1 TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold; KEGG: eca:ECA4132 biotin biosynthesis protein YP_003261453.1 involved in high-affinity gluconate transport YP_003261454.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_003261455.1 amylomaltase; acts to release glucose from maltodextrins YP_003261456.1 KEGG: pct:PC1_3928 glycogen/starch/alpha-glucan phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_003261457.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_003261458.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_003261459.1 KEGG: ect:ECIAI39_4374 carbohydrate kinase; TIGRFAM: ribokinase; PFAM: PfkB domain protein; regulatory protein DeoR; phosphomethylpyrimidine kinase type-1; SMART: regulatory protein DeoR YP_003261460.1 PFAM: dihydrodipicolinate synthetase; KEGG: dda:Dd703_0301 dihydrodipicolinate synthetase YP_003261461.1 PFAM: conserved hypothetical protein; KEGG: dda:Dd703_0300 hypothetical protein YP_003261462.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: dda:Dd703_0299 major facilitator superfamily MFS_1 YP_003261463.1 KEGG: pct:PC1_3931 thiosulfate sulfurtransferase; PFAM: rhodanese; SMART: rhodanese YP_003261464.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_003261466.1 KEGG: pct:PC1_3933 glycogen/starch/alpha-glucan phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_003261467.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_003261468.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_003261469.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_003261470.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_003261471.1 KEGG: pct:PC1_3938 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: GAF domain protein YP_003261473.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_003261474.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_003261475.1 PFAM: glycoside hydrolase; KEGG: eca:ECA4161 beta-hexosaminidase YP_003261476.1 PFAM: pirin; Cupin 2 conserved barrel domain protein; KEGG: eca:ECA4162 hypothetical protein YP_003261477.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_003261478.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_003261479.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_003261480.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_003261481.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_003261482.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_003261483.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: lysine exporter protein (LYSE/YGGA); KEGG: eca:ECA4170 homoserine/homoserine lactone efflux protein YP_003261484.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: lysine exporter protein (LYSE/YGGA); KEGG: pct:PC1_3963 homoserine/threonine efflux pump YP_003261485.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_003261486.1 catalyzes the hydrolysis of phosphatidylcholine YP_003261487.1 PFAM: thioesterase superfamily protein; KEGG: pct:PC1_3966 thioesterase superfamily protein YP_003261488.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: pct:PC1_3967 RarD protein, DMT superfamily transporter YP_003261489.1 TIGRFAM: membrane protein AbrB duplication; PFAM: ammonia monooxygenase; KEGG: eca:ECA4176 hypothetical protein YP_003261490.1 responsible for the influx of magnesium ions YP_003261491.1 PFAM: cyclase family protein; KEGG: pct:PC1_3970 cyclase family protein YP_003261492.1 KEGG: eca:ECA0178 hypothetical protein YP_003261493.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_003261494.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_003261495.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_003261496.1 PFAM: protein of unknown function DUF484; KEGG: pct:PC1_3974 hypothetical protein YP_003261497.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_003261498.1 KEGG: eca:ECA4184 lipoprotein YP_003261499.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_003261500.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4186 hypothetical protein YP_003261501.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_003261502.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_003261503.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_003261504.1 PFAM: protein of unknown function DUF513 hemX; KEGG: pct:PC1_3982 uroporphyrinogen-III C-methyltransferase YP_003261505.1 TIGRFAM: HemY protein; PFAM: HemY domain protein; hypothetical protein; KEGG: eca:ECA4191 protoheme IX biogenesis protein YP_003261506.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: pct:PC1_3984 transcriptional regulator, GntR family YP_003261507.1 PFAM: MmgE/PrpD family protein; KEGG: pct:PC1_3985 MmgE/PrpD family protein YP_003261508.1 PFAM: MmgE/PrpD family protein; KEGG: pct:PC1_3986 MmgE/PrpD family protein YP_003261509.1 PFAM: protein of unknown function DUF81; KEGG: pct:PC1_3987 hypothetical protein YP_003261510.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: pct:PC1_3988 extracellular solute-binding protein family 3 YP_003261511.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_3989 polar amino acid ABC transporter inner membrane protein YP_003261512.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_3990 polar amino acid ABC transporter inner membrane protein YP_003261513.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_3991 ABC transporter YP_003261514.1 KEGG: eca:ECA4192 peptidase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_003261515.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_3993 ABC transporter YP_003261516.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4194 amino-acid ABC transporter permease YP_003261517.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4195 amino-acid ABC transporter binding protein YP_003261518.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_3996 GCN5-related N-acetyltransferase YP_003261519.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_003261520.1 PFAM: histidine acid phosphatase; KEGG: eca:ECA4198 exported phosphatase YP_003261521.1 PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: kpe:KPK_1827 glycerol dehydrogenase YP_003261522.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4195 amino-acid ABC transporter binding protein YP_003261523.1 KEGG: pct:PC1_4000 glycosyl transferase, WecB/TagA/CpsF family; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF YP_003261524.1 enterobacterial common antigen polymerase YP_003261525.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_003261526.1 PFAM: polysaccharide biosynthesis protein; KEGG: pct:PC1_4003 polysaccharide biosynthesis protein YP_003261527.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_003261528.1 TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_4005 TDP-D-fucosamine acetyltransferase YP_003261529.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: eca:ECA4206 dTDP-glucose 4,6-dehydratase YP_003261530.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_003261531.1 KEGG: pct:PC1_4008 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase YP_003261532.1 Enterobacterial Common antigen (ECA) polysaccharide chain length modulation protein YP_003261533.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase, family 4, conserved region; KEGG: eca:ECA4210 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase YP_003261534.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_003261535.1 TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: eca:ECA4212 thioredoxin YP_003261536.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_003261537.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_003261538.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_003261539.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: eca:ECA4216 peptidyl-prolyl cis-trans isomerase C YP_003261540.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_003261541.1 TIGRFAM: sodium/proline symporter; SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: eca:ECA4218 sodium/proline symporter YP_003261542.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: pct:PC1_4019 LysR family transcriptional regulator YP_003261543.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; KEGG: eca:ECA4220 hypothetical protein YP_003261544.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_003261545.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_003261546.1 KEGG: eca:ECA4223 hypothetical protein YP_003261547.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA4224 hypothetical protein YP_003261548.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_003261549.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_003261550.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_003261551.1 KEGG: eca:ECA4228 acetolactate synthase 2 regulatory subunit YP_003261552.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_003261554.1 KEGG: eca:ECA4230 magnesium-chelatase; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA YP_003261555.1 PFAM: protein of unknown function DUF413; KEGG: pct:PC1_4034 hypothetical protein YP_003261556.1 negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_003261557.1 membrane component of a sugar ABC transporter system YP_003261558.1 PFAM: inner-membrane translocator; KEGG: pct:PC1_4037 inner-membrane translocator YP_003261559.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA4235 ABC transporter ATP-binding protein YP_003261560.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: pct:PC1_4039 periplasmic binding protein/LacI transcriptional regulator YP_003261561.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_003261562.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: eca:ECA0211 potassium transporter YP_003261563.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: pct:PC1_4042 hypothetical protein YP_003261564.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_003261565.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_003261566.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_003261567.1 KEGG: pmr:PMI1215 hypothetical protein YP_003261568.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_003261569.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_003261570.1 KEGG: pct:PC1_4048 transcriptional acivator RfaH; TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; SMART: NGN domain protein YP_003261571.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_003261572.1 magnesium dependent; not involved in the Sec-independent protein export system YP_003261573.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_003261574.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: eca:ECA0200 sec-independent protein translocase YP_003261575.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: eca:ECA0199 sec-independent protein translocase YP_003261576.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_003261577.1 PFAM: sterol-binding domain protein; KEGG: pct:PC1_4055 sterol-binding domain protein YP_003261578.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: pct:PC1_4056 ubiquinone/menaquinone biosynthesis methyltransferase YP_003261579.1 PFAM: protein of unknown function DUF195; KEGG: eca:ECA0195 DNA recombination protein YP_003261580.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_003261581.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_003261582.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_003261583.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_003261584.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: eca:ECA0190 GntR family transcriptional regulator YP_003261585.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0189 mandelate racemase / muconate lactonizing enzyme YP_003261586.1 PFAM: phosphotransferase system EIIC; phosphotransferase system EIIB/cysteine, phosphorylation site; KEGG: eca:ECA0188 PTS system, IIABC component YP_003261587.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: pct:PC1_0054 type VI secretion system effector, Hcp1 family YP_003261588.1 TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein; PFAM: Rhs element Vgr protein; KEGG: dze:Dd1591_2559 type VI secretion system Vgr family protein YP_003261589.1 PFAM: PAAR repeat-containing protein; KEGG: dze:Dd1591_2560 PaaR repeat-containing protein YP_003261590.1 KEGG: ecz:ECS88_3099 hypothetical protein YP_003261593.1 SMART: ankyrin; KEGG: pct:PC1_3236 ankyrin YP_003261594.1 SMART: ankyrin; KEGG: eca:ECA3424 lipoprotein YP_003261595.1 SMART: ankyrin; KEGG: eca:ECA3425 lipoprotein YP_003261596.1 PFAM: ankyrin; SMART: ankyrin; KEGG: pct:PC1_3236 ankyrin YP_003261597.1 KEGG: pct:PC1_3234 hypothetical protein YP_003261599.1 PFAM: cell wall assembly/cell proliferation coordinating protein, KNR4-like; KEGG: pfl:PFL_4085 hypothetical protein YP_003261600.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: eca:ECA4289 hypothetical protein YP_003261602.1 KEGG: eca:ECA3411 hypothetical protein YP_003261603.1 KEGG: yps:YPTB3279 hypothetical protein YP_003261607.1 PFAM: cell wall assembly/cell proliferation coordinating protein, KNR4-like; KEGG: plu:plu0342 hypothetical protein YP_003261608.1 KEGG: pay:PAU_01169 hypothetical protein YP_003261609.1 KEGG: eca:ECA2119 hypothetical protein YP_003261610.1 KEGG: aci:ACIAD2705 hypothetical protein YP_003261611.1 KEGG: eca:ECA3402 hypothetical protein YP_003261612.1 PFAM: cell wall assembly/cell proliferation coordinating protein, KNR4-like; KEGG: bcj:BCAS0662 hypothetical protein YP_003261613.1 PFAM: Domain of unknown function DUF1813 HSP20-like; KEGG: eca:ECA3402 hypothetical protein YP_003261615.1 KEGG: hch:HCH_03841 hypothetical protein YP_003261616.1 KEGG: efe:EFER_1460 hypothetical protein YP_003261618.1 PFAM: cell wall assembly/cell proliferation coordinating protein, KNR4-like; KEGG: plu:plu0342 hypothetical protein YP_003261619.1 PFAM: cell wall assembly/cell proliferation coordinating protein, KNR4-like; KEGG: esa:ESA_03887 hypothetical protein YP_003261624.1 KEGG: eum:ECUMN_4031 hypothetical protein YP_003261625.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA4305 LysR family transcriptional regulator YP_003261626.1 KEGG: eca:ECA4304 hypothetical protein YP_003261627.1 KEGG: eca:ECA4303 hypothetical protein YP_003261628.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pct:PC1_0144 TonB-dependent receptor YP_003261629.1 PFAM: NMT1/THI5 like domain protein; KEGG: eca:ECA4301 sulfate ester binding protein YP_003261630.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: eca:ECA4300 TonB protein YP_003261631.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: pct:PC1_0147 MotA/TolQ/ExbB proton channel YP_003261632.1 PFAM: biopolymertransporter ExbD/TolR; KEGG: pct:PC1_0148 biopolymer transporter ExbD/TolR YP_003261633.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4297 sulfate ester ABC transporter permease protein YP_003261634.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA4296 sulfate ester ABC transporter ATP-binding protein YP_003261635.1 KEGG: vap:Vapar_5783 hypothetical protein YP_003261637.1 KEGG: pct:PC1_3226 hypothetical protein YP_003261638.1 KEGG: esa:ESA_pESA3p05511 hypothetical protein YP_003261639.1 KEGG: plu:plu0341 hypothetical protein YP_003261640.1 KEGG: pst:PSPTO_0093 hypothetical protein YP_003261641.1 PFAM: Barstar (barnase inhibitor); KEGG: pct:PC1_3227 barstar (barnase inhibitor) YP_003261642.1 KEGG: yps:YPTB3279 hypothetical protein YP_003261643.1 KEGG: plu:plu3111 hypothetical protein YP_003261645.1 KEGG: pct:PC1_3229 hypothetical protein YP_003261648.1 KEGG: pay:PAU_03002 hypothetical protein YP_003261649.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_003261650.1 KEGG: eca:ECA0186 hypothetical protein YP_003261651.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_003261652.1 PFAM: dienelactone hydrolase; KEGG: eca:ECA0184 carboxymethylenebutenolidase YP_003261653.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0183 methyl-accepting chemotaxis protein YP_003261654.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_4072 methyl-accepting chemotaxis sensory transducer YP_003261655.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_003261656.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0180 transcriptional activator protein YP_003261657.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: eca:ECA0179 hypothetical protein YP_003261659.1 catalyzes the transfer of palmitate to lipid A YP_003261660.1 catalyzes the O-acetylation of serine YP_003261661.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_003261662.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_003261663.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: pct:PC1_4083 rhodanese domain protein YP_003261664.1 PFAM: peptidase M23; KEGG: pct:PC1_4084 peptidase M23 YP_003261665.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: pct:PC1_4085 hypothetical protein YP_003261666.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_003261667.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_003261668.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_003261669.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_003261670.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: eca:ECA0163 ADP-heptose:LPS heptosyl transferase I YP_003261671.1 PFAM: O-antigen polymerase; KEGG: eca:ECA0162 O-antigen ligase YP_003261673.1 PFAM: O-antigen polymerase; KEGG: eca:ECA0161 O-antigen ligase YP_003261674.1 TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: eca:ECA0160 lipopolysaccharide core biosynthesis protein YP_003261675.1 PFAM: glycosyl transferase group 1; KEGG: eca:ECA0159 lipopolysaccharide core biosynthesis protein YP_003261676.1 PFAM: glycosyl transferase family 8; glycosyl transferase family 8 domain protein; KEGG: eca:ECA0158 lipopolysaccharide 1,3-galactosyltransferase YP_003261677.1 PFAM: glycosyl transferase family 8; glycosyl transferase family 8 domain protein; KEGG: eca:ECA0157 lipopolysaccharide 1,2-glucosyltransferase YP_003261678.1 KEGG: eca:ECA0156 hypothetical protein YP_003261680.1 PFAM: glycosyl transferase family 25; KEGG: eca:ECA0154 beta1,4-galactosyltransferase YP_003261681.1 PFAM: glycosyl transferase family 2; KEGG: eca:ECA0153 lipopolysaccharide core biosynthesis glycosyl transferase YP_003261682.1 PFAM: glycosyltransferase sugar-binding region containing DXD motif; KEGG: eca:ECA0152 glycosyltransferase YP_003261683.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_003261684.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_003261685.1 PFAM: glycosyl transferase group 1; KEGG: cvi:CV_0824 lipopolysaccharide biosynthesis protein YP_003261686.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_003261687.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_003261688.1 required for 70S ribosome assembly YP_003261689.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_003261690.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_003261691.1 catalyzes the formation of dUMP from dUTP YP_003261692.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_003261693.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_003261694.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_003261695.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: eca:ECA0139 mandelate racemase / muconate lactonizing enzyme family protein YP_003261696.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter; SMART: ATPase AAA; KEGG: pct:PC1_4108 ABC transporter related YP_003261697.1 PFAM: extracellular solute-binding protein family 5; KEGG: pct:PC1_4109 extracellular solute-binding protein family 5 YP_003261698.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_4110 binding-protein-dependent transport systems inner membrane component YP_003261699.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_4111 binding-protein-dependent transport systems inner membrane component YP_003261700.1 PFAM: peptidase S58 DmpA; KEGG: eca:ECA0134 peptidase YP_003261701.1 PFAM: peptidase M55 D-aminopeptidase; KEGG: eca:ECA0133 hypothetical protein YP_003261702.1 PFAM: peptidase T2 asparaginase 2; KEGG: eca:ECA0132 L-asparaginase YP_003261703.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: eca:ECA0131 LysR family transcriptional regulator YP_003261704.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: eca:ECA0130 hypothetical protein YP_003261705.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: pct:PC1_4123 transcriptional regulator, XRE family YP_003261706.1 KEGG: eca:ECA0125 hypothetical protein YP_003261707.1 KEGG: pct:PC1_4127 lipoprotein YP_003261708.1 KEGG: pct:PC1_4128 lipoprotein YP_003261709.1 KEGG: pct:PC1_4129 hypothetical protein YP_003261710.1 PFAM: protein of unknown function UPF0118; KEGG: eca:ECA0120 hypothetical protein YP_003261711.1 PFAM: protein of unknown function UPF0157; KEGG: pct:PC1_4131 hypothetical protein YP_003261712.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_003261713.1 NAD-linked YP_003261714.1 KEGG: eca:ECA0117 hypothetical protein YP_003261715.1 PFAM: fatty acid desaturase; KEGG: pct:PC1_4135 fatty acid desaturase YP_003261716.1 PFAM: fatty acid desaturase; KEGG: eca:ECA0115 fatty acid desaturase YP_003261717.1 PFAM: fatty acid hydroxylase; KEGG: eca:ECA0114 hypothetical protein YP_003261718.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: eca:ECA0113 hypothetical protein YP_003261719.1 TIGRFAM: adenylate-forming enzyme; KEGG: eca:ECA0112 hypothetical protein YP_003261720.1 PFAM: beta-lactamase; KEGG: pct:PC1_4140 beta-lactamase YP_003261721.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: eca:ECA0110 hypothetical protein YP_003261722.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: eca:ECA0109 hypothetical protein YP_003261723.1 PFAM: GlpM family protein; KEGG: eca:ECA0108 hypothetical protein YP_003261724.1 SMART: rhodanese; KEGG: ecf:ECH74115_2149 rhodanese domain protein YP_003261725.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism YP_003261726.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_003261727.1 PFAM: Autoinducer-binding domain protein; regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: dze:Dd1591_0100 LuxR family transcriptional regulator YP_003261728.1 PFAM: autoinducer synthesis protein; KEGG: eca:ECA0105 N-acylhomoserine lactone synthesis protein YP_003261729.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_003261730.1 PFAM: ThiJ/PfpI domain protein; KEGG: eca:ECA0102 hypothetical protein YP_003261731.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; KEGG: eca:ECA0101 xylose operon regulatory protein YP_003261733.1 PFAM: inner-membrane translocator; KEGG: eca:ECA0100 xylose transporter permease YP_003261734.1 with XylFH is part of the high affinity xylose ABC transporter YP_003261735.1 periplasmic substrate-binding component of the ATP-dependent xylose transporter; high affinity YP_003261736.1 catalyzes the interconversion of D-xylose to D-xylulose YP_003261737.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY-like; KEGG: eca:ECA0096 xylulose kinase YP_003261738.1 PFAM: acyltransferase 3; KEGG: eca:ECA0095 hypothetical protein YP_003261739.1 PFAM: aldehyde dehydrogenase; KEGG: eca:ECA0094 aldehyde dehydrogenase B YP_003261740.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_003261741.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_003261742.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: eca:ECA0091 methyl-accepting chemotaxis protein YP_003261743.1 KEGG: eca:ECA0090 hypothetical protein YP_003261744.1 Acts as a repressor of the mtlAD operon YP_003261745.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: pct:PC1_4164 mannitol dehydrogenase domain protein YP_003261746.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: pct:PC1_4165 PTS system, mannitol-specific IIC subunit YP_003261747.1 KEGG: eca:ECA0086 hypothetical protein YP_003261748.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003261749.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003261750.1 PFAM: protein of unknown function DUF81; KEGG: pct:PC1_4169 hypothetical protein YP_003261751.1 KEGG: eca:ECA0082 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_003261752.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pct:PC1_4171 GCN5-related N-acetyltransferase YP_003261753.1 PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; KEGG: pct:PC1_4172 methyl-accepting chemotaxis sensory transducer YP_003261754.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: pct:PC1_4173 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding YP_003261755.1 PFAM: extracellular solute-binding protein family 5; KEGG: pct:PC1_4174 extracellular solute-binding protein family 5 YP_003261756.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_4175 binding-protein-dependent transport systems inner membrane component YP_003261757.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: pct:PC1_4176 binding-protein-dependent transport systems inner membrane component YP_003261758.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: eca:ECA0072 ABC transporter ATP-binding protein YP_003261759.1 PFAM: Luciferase-like, subgroup; KEGG: eca:ECA0071 monooxygenase YP_003261760.1 TIGRFAM: peroxidase; alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: eca:ECA0070 hypothetical protein YP_003261761.1 PFAM: ricin B lectin; KEGG: ret:RHE_PA00136 hypothetical protein YP_003261762.1 PFAM: Phenolic acid decarboxylase; KEGG: eca:ECA0069 phenolic acid decarboxylase YP_003261763.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: eca:ECA0068 LysR family transcriptional regulator YP_003261764.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: eca:ECA0067 amino acid transporter LysE YP_003261765.1 PFAM: protein of unknown function UPF0167; KEGG: pap:PSPA7_3797 hypothetical protein YP_003261766.1 PFAM: FAD-binding 9 siderophore-interacting domain protein; Siderophore-interacting protein; KEGG: pct:PC1_4183 FAD-binding 9 siderophore-interacting domain protein YP_003261767.1 KEGG: bbt:BBta_4640 hypothetical protein YP_003261769.1 KEGG: vfi:VF_A0980 hypothetical protein YP_003261770.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_003261771.1 PFAM: protein of unknown function DUF519; KEGG: eca:ECA0061 hypothetical protein YP_003261772.1 PFAM: protein of unknown function DUF1266; KEGG: pct:PC1_4188 hypothetical protein YP_003261773.1 PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: pct:PC1_4189 heat shock protein DnaJ domain protein YP_003261774.1 PFAM: heat shock protein 70; KEGG: pct:PC1_4190 heat shock protein 70 YP_003261775.1 KEGG: eca:ECA0060 hypothetical protein YP_003261778.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: pct:PC1_4196 oligopeptidase A YP_003261779.1 predicted SAM-dependent methyltransferase YP_003261780.1 PFAM: 5'-nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA0053 phosphodiesterase YP_003261781.1 PFAM: FAD dependent oxidoreductase; KEGG: eca:ECA0052 hypothetical protein YP_003261782.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_003261783.1 PFAM: UspA domain protein; KEGG: pct:PC1_4201 UspA domain protein YP_003261784.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_003261785.1 PFAM: phosphate transporter; KEGG: pct:PC1_4203 phosphate transporter YP_003261786.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: pct:PC1_4204 HI0933 family protein YP_003261787.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: pct:PC1_4205 EAL domain protein YP_003261788.1 PFAM: virulence-related outer membrane protein; KEGG: eca:ECA0045 virulence-associated outer membrane protein YP_003261789.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_003261790.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_003261791.1 Essential for recycling GMP and indirectly, cGMP YP_003261792.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and subunit alphas YP_003261793.1 KEGG: pct:PC1_4211 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: RelA/SpoT domain protein; TGS domain protein; amino acid-binding ACT domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_003261794.1 specifically modifies tRNA at position G18 YP_003261795.1 catalyzes branch migration in Holliday junction intermediates YP_003261796.1 TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: eca:ECA0035 purine permease YP_003261797.1 PFAM: AsmA family protein; KEGG: pct:PC1_4215 AsmA family protein YP_003261798.1 TIGRFAM: thioesterase domain protein; PFAM: thioesterase ; GCN5-related N-acetyltransferase; KEGG: eca:ECA0033 GNAT family acetyltransferase YP_003261799.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); defense mechanism against a harmful effect of D-tyrosine YP_003261800.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: eca:ECA0031 phosphatase YP_003261801.1 TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: eca:ECA0030 GTP-binding regulatory protein YP_003261802.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_003261803.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_003261804.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_003261805.1 KEGG: pct:PC1_4223 hypothetical protein YP_003261806.1 KEGG: avn:Avin_09722 DsbA oxidoreductase YP_003261808.1 TIGRFAM: ferredoxin [2Fe-2S]; PFAM: ferredoxin; KEGG: FED_A; FED A (FERREDOXIN 2); 2 iron, 2 sulfur cluster binding / electron carrier/ iron-sulfur cluster binding ; K02639 ferredoxin YP_003261809.1 KEGG: dze:Dd1591_1323 hypothetical protein YP_003261811.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_003261812.1 PFAM: protein of unknown function DUF414; KEGG: eca:ECA0024 hypothetical protein YP_003261813.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_003261814.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_003261815.1 PFAM: DSBA oxidoreductase; KEGG: eca:ECA0020 periplasmic protein disulfide isomerase I YP_003261816.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_003261817.1 PFAM: protein of unknown function DUF1040; KEGG: pct:PC1_4230 hypothetical protein YP_003261818.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_003261819.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_003261820.1 DNA-binding transcriptional repressor of ribose metabolism YP_003261821.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_003261822.1 periplasmic substrate-binding component of the ATP-dependent ribose transporter YP_003261823.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_003261824.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_003261825.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_003261826.1 PFAM: conserved hypothetical protein; KEGG: eca:ECA0009 hypothetical protein YP_003261827.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pct:PC1_4240 transcriptional regulator YP_003261828.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pct:PC1_4241 histidine kinase YP_003261829.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_003261830.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_003261831.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_003261832.1 catalyzes the formation of asparagine from aspartate and ammonia YP_003261833.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_003261834.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_003261835.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_003261836.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_003261837.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_003261838.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_003261839.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_003261840.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_003261841.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the subunit delta is part of the catalytic core of the ATP synthase complex YP_003261842.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_003261843.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_003261844.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_003261845.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_003261846.1 TIGRFAM: N-formylglutamate amidohydrolase; PFAM: N-formylglutamate amidohydrolase; KEGG: pfl:PFL_0410 N-formylglutamate amidohydrolase YP_003261847.1 TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; amidohydrolase; KEGG: pae:PA5092 imidazolonepropionase YP_003261848.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_003261849.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: avi:Avi_0501 ABC transporter nucleotide binding/ATPase protein (proline/glycine/betaine) YP_003261850.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: avi:Avi_0502 ABC transporter membrane spanning protein (proline/glycine/betaine) YP_003261851.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ara:Arad_8400 proline/glycine betaine ABC transporter YP_003261852.1 PFAM: substrate-binding region of ABC-type glycine betaine transporter; KEGG: ara:Arad_8402 substrate-binding region of ABC-type glycine betaine transporter YP_003261853.1 KEGG: ara:Arad_8403 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase YP_003261854.1 PFAM: protein of unknown function DUF886; KEGG: pen:PSEEN5098 hypothetical protein YP_003261855.1 KEGG: ppu:PP_5035 histidine utilization repressor; TIGRFAM: histidine utilization repressor; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH YP_003261856.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_003261857.1 KEGG: eca:ECA4510 exopolygalacturonate lyase YP_003261858.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_003261859.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_003261860.1 KEGG: eca:ECA4507 lipoprotein YP_003261861.1 PFAM: O-methyltransferase family 2; methyltransferase type 12; KEGG: efe:EFER_3450 methyltransferase YP_003261862.1 KEGG: eca:ECA4506 hypothetical protein YP_003261863.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: eca:ECA4505 acyltransferase YP_003261864.1 KEGG: eca:ECA4504 acyl carrier protein YP_003261865.1 carries the fatty acid chain in fatty acid biosynthesis YP_003261866.1 KEGG: eca:ECA4502 hypothetical protein YP_003261867.1 PFAM: AMP-dependent synthetase and ligase; KEGG: eca:ECA4501 AMP-binding enzyme YP_003261868.1 PFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: eca:ECA4500 hypothetical protein YP_003261869.1 PFAM: glycosyl transferase family 2; KEGG: eca:ECA4499 glycosyl transferase YP_003261870.1 PFAM: thioesterase superfamily protein; KEGG: eca:ECA4498 thioesterase YP_003261871.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: eca:ECA4497 hypothetical protein YP_003261872.1 KEGG: eca:ECA4496 hypothetical protein YP_003261873.1 KEGG: eca:ECA4495 lipoprotein YP_003261874.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_003261875.1 PFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: eca:ECA4493 beta-hydroxydecanoyl-ACP dehydrase YP_003261876.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_003261877.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_003261878.1 PFAM: metallophosphoesterase; KEGG: sgl:SG1888 hypothetical protein YP_003261879.1 TIGRFAM: phosphate ABC transporter periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: pct:PC1_4263 phosphate ABC transporter periplasmic phosphate-binding protein YP_003261880.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_003261881.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_003261882.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_003261883.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_003261884.1 PFAM: cupin; hypothetical protein; SMART: hypothetical protein; KEGG: eca:ECA4472 DNA-binding protein YP_003261885.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transporter; xanthine/uracil/vitamin C permease; KEGG: eca:ECA4471 benzoate transporter YP_003261886.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: eca:ECA4470 extracellular solute-binding protein YP_003261887.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4468 binding-protein-dependent transporter inner membrane component YP_003261888.1 TIGRFAM: polar amino acid ABC transporter inner membrane protein; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: eca:ECA4467 binding-protein-dependent transporter inner membrane component YP_003261889.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_003261890.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: pct:PC1_4275 xanthine/uracil/vitamin C permease YP_003261891.1 KEGG: eca:ECA4463 hypothetical protein YP_003261892.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pct:PC1_4277 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_003261893.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_003261895.1 PFAM: Curli production assembly/transport component CsgG; KEGG: pct:PC1_4279 curli production assembly/transport component CsgG YP_003261896.1 KEGG: eca:ECA4459 lipoprotein YP_003261897.1 PFAM: protein of unknown function DUF799; KEGG: eca:ECA4458 lipoprotein YP_003261898.1 PFAM: major facilitator superfamily MFS_1; KEGG: eca:ECA4457 methyl viologen resistance protein YP_003261899.1 KEGG: pct:PC1_4283 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003261900.1 KEGG: pct:PC1_4284 hypothetical protein YP_003261901.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia YP_003261902.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export YP_003261903.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_003261904.1 KEGG: eca:ECA4451 hemin storage protein YP_003261905.1 PFAM: helix-turn-helix HxlR type; KEGG: pct:PC1_4289 HxlR family transcriptional regulator YP_003261906.1 PFAM: NmrA family protein; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: pct:PC1_4290 NmrA family protein YP_003261907.1 PFAM: acyltransferase 3; KEGG: pct:PC1_4291 acyltransferase 3 YP_003261908.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: plu:plu4901 HipB protein YP_003261909.1 KEGG: plu:plu4900 HipA protein YP_003261910.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_003261911.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_003261912.1 KEGG: pct:PC1_4294 hypothetical protein YP_003261913.1 in Escherichia coli transcription of this gene is enhanced by polyamines