-- dump date   	20140619_232737
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
762903000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
762903000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
762903000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903000004	Walker A motif; other site
762903000005	ATP binding site [chemical binding]; other site
762903000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
762903000007	Walker B motif; other site
762903000008	arginine finger; other site
762903000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
762903000010	DnaA box-binding interface [nucleotide binding]; other site
762903000011	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
762903000012	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
762903000013	dimer interface [polypeptide binding]; other site
762903000014	ADP-ribose binding site [chemical binding]; other site
762903000015	active site
762903000016	nudix motif; other site
762903000017	metal binding site [ion binding]; metal-binding site
762903000018	Repair protein; Region: Repair_PSII; pfam04536
762903000019	Repair protein; Region: Repair_PSII; pfam04536
762903000020	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
762903000021	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
762903000022	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
762903000023	CoA binding domain; Region: CoA_binding_2; pfam13380
762903000024	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
762903000025	S-formylglutathione hydrolase; Region: PLN02442
762903000026	Putative esterase; Region: Esterase; pfam00756
762903000027	PCI domain; Region: PCI; cl02111
762903000028	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
762903000029	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
762903000030	nucleotide binding site [chemical binding]; other site
762903000031	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
762903000032	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
762903000033	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
762903000034	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
762903000035	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
762903000036	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
762903000037	active site
762903000038	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
762903000039	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903000040	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903000041	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903000042	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903000043	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903000044	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903000045	SusD family; Region: SusD; pfam07980
762903000046	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
762903000047	muropeptide transporter; Reviewed; Region: ampG; PRK11902
762903000048	muropeptide transporter; Validated; Region: ampG; cl17669
762903000049	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
762903000050	active site
762903000051	catalytic triad [active]
762903000052	oxyanion hole [active]
762903000053	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
762903000054	active site
762903000055	catalytic triad [active]
762903000056	oxyanion hole [active]
762903000057	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
762903000058	dimerization interface [polypeptide binding]; other site
762903000059	putative active cleft [active]
762903000060	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
762903000061	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
762903000062	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
762903000063	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Deinococcus radiodurans DR2231 protein and its bacterial homologs; Region: NTP-PPase_DR2231_like; cd11530
762903000064	metal binding site [ion binding]; metal-binding site
762903000065	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
762903000066	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
762903000067	putative DNA binding site [nucleotide binding]; other site
762903000068	putative Zn2+ binding site [ion binding]; other site
762903000069	AsnC family; Region: AsnC_trans_reg; pfam01037
762903000070	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903000071	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903000072	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
762903000073	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
762903000074	metal-binding site [ion binding]
762903000075	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
762903000076	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903000077	motif II; other site
762903000078	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
762903000079	metal-binding site [ion binding]
762903000080	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
762903000081	active site
762903000082	catalytic residues [active]
762903000083	thymidine kinase; Provisional; Region: PRK04296
762903000084	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
762903000085	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
762903000086	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
762903000087	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
762903000088	rod shape-determining protein MreC; Provisional; Region: PRK13922
762903000089	rod shape-determining protein MreC; Region: MreC; pfam04085
762903000090	rod shape-determining protein MreB; Provisional; Region: PRK13927
762903000091	MreB and similar proteins; Region: MreB_like; cd10225
762903000092	nucleotide binding site [chemical binding]; other site
762903000093	Mg binding site [ion binding]; other site
762903000094	putative protofilament interaction site [polypeptide binding]; other site
762903000095	RodZ interaction site [polypeptide binding]; other site
762903000096	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
762903000097	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903000098	Domain of unknown function DUF11; Region: DUF11; cl17728
762903000099	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903000100	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903000101	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903000102	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903000103	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903000104	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903000105	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903000106	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
762903000107	Putative carbohydrate binding domain; Region: CHB_HEX; cl03918
762903000108	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
762903000109	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
762903000110	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
762903000111	active site
762903000112	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
762903000113	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
762903000114	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
762903000115	purine monophosphate binding site [chemical binding]; other site
762903000116	dimer interface [polypeptide binding]; other site
762903000117	putative catalytic residues [active]
762903000118	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
762903000119	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
762903000120	Domain of unknown function (DUF4377); Region: DUF4377; pfam14302
762903000121	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
762903000122	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
762903000123	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903000124	active site
762903000125	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
762903000126	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
762903000127	active site
762903000128	substrate binding site [chemical binding]; other site
762903000129	metal binding site [ion binding]; metal-binding site
762903000130	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
762903000131	active site
762903000132	Lyase, N terminal; Region: Lyase_N; pfam09092
762903000133	Lyase, catalytic; Region: Lyase_catalyt; pfam09093
762903000134	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cl17706
762903000135	catalytic residues [active]
762903000136	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903000137	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903000138	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903000139	Sulfatase; Region: Sulfatase; cl17466
762903000140	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903000141	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903000142	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903000143	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903000144	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903000145	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903000146	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903000147	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903000148	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903000149	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903000150	DNA binding residues [nucleotide binding]
762903000151	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903000152	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903000153	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903000154	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
762903000155	Domain of unknown function DUF21; Region: DUF21; pfam01595
762903000156	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
762903000157	Transporter associated domain; Region: CorC_HlyC; smart01091
762903000158	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980
762903000159	FecR protein; Region: FecR; pfam04773
762903000160	Secretin and TonB N terminus short domain; Region: STN; pfam07660
762903000161	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903000162	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903000163	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903000164	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903000165	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
762903000166	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903000167	IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the...; Region: IPT_PCSR; cd00603
762903000168	NHL repeat; Region: NHL; pfam01436
762903000169	NHL repeat; Region: NHL; pfam01436
762903000170	NHL repeat; Region: NHL; pfam01436
762903000171	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
762903000172	PLD-like domain; Region: PLDc_2; pfam13091
762903000173	putative active site [active]
762903000174	catalytic site [active]
762903000175	PLD-like domain; Region: PLDc_2; pfam13091
762903000176	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
762903000177	putative active site [active]
762903000178	catalytic site [active]
762903000179	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903000180	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
762903000181	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903000182	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903000183	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903000184	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
762903000185	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
762903000186	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
762903000187	Transposase IS200 like; Region: Y1_Tnp; cl00848
762903000188	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903000189	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903000190	FOG: Ankyrin repeat [General function prediction only]; Region: Arp; COG0666
762903000191	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903000192	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903000193	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903000194	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903000195	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903000196	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903000197	Predicted periplasmic protein (DUF2271); Region: DUF2271; pfam10029
762903000198	Peptidase propeptide and YPEB domain; Region: PepSY_2; pfam13670
762903000199	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
762903000200	Flavodoxin; Region: Flavodoxin_1; pfam00258
762903000201	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
762903000202	FAD binding pocket [chemical binding]; other site
762903000203	conserved FAD binding motif [chemical binding]; other site
762903000204	phosphate binding motif [ion binding]; other site
762903000205	beta-alpha-beta structure motif; other site
762903000206	NAD binding pocket [chemical binding]; other site
762903000207	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
762903000208	ApbE family; Region: ApbE; pfam02424
762903000209	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
762903000210	Transposase; Region: DEDD_Tnp_IS110; pfam01548
762903000211	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
762903000212	Protein of unknown function DUF72; Region: DUF72; pfam01904
762903000213	Fatty acid desaturase; Region: FA_desaturase; pfam00487
762903000214	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
762903000215	putative di-iron ligands [ion binding]; other site
762903000216	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
762903000217	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
762903000218	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903000219	motif II; other site
762903000220	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
762903000221	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903000222	catalytic residues [active]
762903000223	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903000224	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903000225	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903000226	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
762903000227	Outer membrane efflux protein; Region: OEP; pfam02321
762903000228	Outer membrane efflux protein; Region: OEP; pfam02321
762903000229	CAAX protease self-immunity; Region: Abi; pfam02517
762903000230	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903000231	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
762903000232	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903000233	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
762903000234	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903000235	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903000236	ligand binding site [chemical binding]; other site
762903000237	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903000238	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903000239	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903000240	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903000241	putative deaminase; Validated; Region: PRK06846
762903000242	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
762903000243	active site
762903000244	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903000245	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903000246	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
762903000247	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
762903000248	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
762903000249	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903000250	Coenzyme A binding pocket [chemical binding]; other site
762903000251	Phosphoglycerate kinase; Region: PGK; pfam00162
762903000252	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
762903000253	substrate binding site [chemical binding]; other site
762903000254	hinge regions; other site
762903000255	ADP binding site [chemical binding]; other site
762903000256	catalytic site [active]
762903000257	Protein of unknown function, DUF488; Region: DUF488; cl01246
762903000258	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
762903000259	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
762903000260	catalytic loop [active]
762903000261	iron binding site [ion binding]; other site
762903000262	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
762903000263	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
762903000264	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
762903000265	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159
762903000266	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
762903000267	apolar tunnel; other site
762903000268	heme binding site [chemical binding]; other site
762903000269	dimerization interface [polypeptide binding]; other site
762903000270	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
762903000271	heme-binding site [chemical binding]; other site
762903000272	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
762903000273	putative bifunctional cbb3-type cytochrome c oxidase subunit II/cytochrome c; Provisional; Region: PRK14486
762903000274	Cytochrome c; Region: Cytochrom_C; pfam00034
762903000275	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
762903000276	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
762903000277	Low-spin heme binding site [chemical binding]; other site
762903000278	D-pathway; other site
762903000279	Putative water exit pathway; other site
762903000280	Binuclear center (active site) [active]
762903000281	K-pathway; other site
762903000282	Putative proton exit pathway; other site
762903000283	Rrf2 family protein; Region: rrf2_super; TIGR00738
762903000284	Transcriptional regulator; Region: Rrf2; pfam02082
762903000285	cell division protein MraZ; Reviewed; Region: PRK00326
762903000286	MraZ protein; Region: MraZ; pfam02381
762903000287	MraZ protein; Region: MraZ; pfam02381
762903000288	MraW methylase family; Region: Methyltransf_5; cl17771
762903000289	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
762903000290	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
762903000291	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
762903000292	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
762903000293	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
762903000294	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
762903000295	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
762903000296	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
762903000297	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
762903000298	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
762903000299	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
762903000300	Mg++ binding site [ion binding]; other site
762903000301	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
762903000302	putative catalytic motif [active]
762903000303	putative substrate binding site [chemical binding]; other site
762903000304	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
762903000305	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
762903000306	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
762903000307	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
762903000308	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
762903000309	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
762903000310	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
762903000311	active site
762903000312	homodimer interface [polypeptide binding]; other site
762903000313	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
762903000314	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
762903000315	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
762903000316	cell division protein FtsA; Region: ftsA; TIGR01174
762903000317	Cell division protein FtsA; Region: FtsA; smart00842
762903000318	Cell division protein FtsA; Region: FtsA; pfam14450
762903000319	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
762903000320	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
762903000321	nucleotide binding site [chemical binding]; other site
762903000322	SulA interaction site; other site
762903000323	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
762903000324	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
762903000325	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
762903000326	catalytic residue [active]
762903000327	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903000328	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903000329	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903000330	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
762903000331	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
762903000332	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
762903000333	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
762903000334	polyphosphate kinase; Provisional; Region: PRK05443
762903000335	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
762903000336	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
762903000337	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
762903000338	domain interface [polypeptide binding]; other site
762903000339	active site
762903000340	catalytic site [active]
762903000341	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
762903000342	putative active site [active]
762903000343	catalytic site [active]
762903000344	exopolyphosphatase; Region: exo_poly_only; TIGR03706
762903000345	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
762903000346	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903000347	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
762903000348	ArsC family; Region: ArsC; pfam03960
762903000349	putative catalytic residues [active]
762903000350	Protein of unknown function (DUF3891); Region: DUF3891; pfam13030
762903000351	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
762903000352	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
762903000353	nucleotide binding pocket [chemical binding]; other site
762903000354	K-X-D-G motif; other site
762903000355	catalytic site [active]
762903000356	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
762903000357	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
762903000358	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
762903000359	Dimer interface [polypeptide binding]; other site
762903000360	BRCT sequence motif; other site
762903000361	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
762903000362	dihydrodipicolinate synthase; Region: dapA; TIGR00674
762903000363	dimer interface [polypeptide binding]; other site
762903000364	active site
762903000365	catalytic residue [active]
762903000366	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
762903000367	classical (c) SDRs; Region: SDR_c; cd05233
762903000368	NAD(P) binding site [chemical binding]; other site
762903000369	active site
762903000370	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
762903000371	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
762903000372	active site
762903000373	HIGH motif; other site
762903000374	dimer interface [polypeptide binding]; other site
762903000375	KMSKS motif; other site
762903000376	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
762903000377	RNA binding surface [nucleotide binding]; other site
762903000378	putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293
762903000379	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
762903000380	RES domain; Region: RES; pfam08808
762903000381	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
762903000382	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
762903000383	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
762903000384	active site
762903000385	catalytic tetrad [active]
762903000386	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
762903000387	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
762903000388	active site
762903000389	catalytic site [active]
762903000390	substrate binding site [chemical binding]; other site
762903000391	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
762903000392	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
762903000393	active site
762903000394	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
762903000395	generic binding surface II; other site
762903000396	generic binding surface I; other site
762903000397	malate dehydrogenase; Reviewed; Region: PRK06223
762903000398	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
762903000399	NAD(P) binding site [chemical binding]; other site
762903000400	dimer interface [polypeptide binding]; other site
762903000401	tetramer (dimer of dimers) interface [polypeptide binding]; other site
762903000402	substrate binding site [chemical binding]; other site
762903000403	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
762903000404	catalytic motif [active]
762903000405	Catalytic residue [active]
762903000406	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
762903000407	heme-binding site [chemical binding]; other site
762903000408	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
762903000409	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903000410	ATP binding site [chemical binding]; other site
762903000411	Mg2+ binding site [ion binding]; other site
762903000412	G-X-G motif; other site
762903000413	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
762903000414	anchoring element; other site
762903000415	dimer interface [polypeptide binding]; other site
762903000416	ATP binding site [chemical binding]; other site
762903000417	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
762903000418	active site
762903000419	putative metal-binding site [ion binding]; other site
762903000420	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
762903000421	Protein of unknown function DUF58; Region: DUF58; pfam01882
762903000422	von Willebrand factor type A domain; Region: VWA_2; pfam13519
762903000423	metal ion-dependent adhesion site (MIDAS); other site
762903000424	Mechanosensitive ion channel; Region: MS_channel; pfam00924
762903000425	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
762903000426	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
762903000427	inhibitor-cofactor binding pocket; inhibition site
762903000428	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903000429	catalytic residue [active]
762903000430	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
762903000431	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903000432	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903000433	DNA binding residues [nucleotide binding]
762903000434	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
762903000435	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
762903000436	PYR/PP interface [polypeptide binding]; other site
762903000437	dimer interface [polypeptide binding]; other site
762903000438	TPP binding site [chemical binding]; other site
762903000439	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
762903000440	transketolase; Reviewed; Region: PRK05899
762903000441	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
762903000442	TPP-binding site [chemical binding]; other site
762903000443	dimer interface [polypeptide binding]; other site
762903000444	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
762903000445	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903000446	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903000447	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903000448	TPR motif; other site
762903000449	binding surface
762903000450	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903000451	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903000452	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903000453	ligand binding site [chemical binding]; other site
762903000454	helicase 45; Provisional; Region: PTZ00424
762903000455	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
762903000456	ATP binding site [chemical binding]; other site
762903000457	Mg++ binding site [ion binding]; other site
762903000458	motif III; other site
762903000459	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903000460	nucleotide binding region [chemical binding]; other site
762903000461	ATP-binding site [chemical binding]; other site
762903000462	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
762903000463	active site
762903000464	intersubunit interactions; other site
762903000465	catalytic residue [active]
762903000466	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
762903000467	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
762903000468	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
762903000469	histidinol-phosphate phosphatase family domain; Region: Histidinol-ppas; TIGR01656
762903000470	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903000471	active site
762903000472	motif I; other site
762903000473	motif II; other site
762903000474	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
762903000475	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
762903000476	active site
762903000477	dimer interface [polypeptide binding]; other site
762903000478	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
762903000479	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
762903000480	active site
762903000481	FMN binding site [chemical binding]; other site
762903000482	substrate binding site [chemical binding]; other site
762903000483	3Fe-4S cluster binding site [ion binding]; other site
762903000484	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
762903000485	domain interface; other site
762903000486	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
762903000487	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
762903000488	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
762903000489	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
762903000490	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
762903000491	ATP binding site [chemical binding]; other site
762903000492	putative Mg++ binding site [ion binding]; other site
762903000493	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903000494	nucleotide binding region [chemical binding]; other site
762903000495	ATP-binding site [chemical binding]; other site
762903000496	DbpA RNA binding domain; Region: DbpA; pfam03880
762903000497	Predicted flavoprotein [General function prediction only]; Region: COG0431
762903000498	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
762903000499	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
762903000500	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
762903000501	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
762903000502	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
762903000503	DoxX-like family; Region: DoxX_2; pfam13564
762903000504	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
762903000505	hydrophobic ligand binding site; other site
762903000506	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
762903000507	dimerization interface [polypeptide binding]; other site
762903000508	putative DNA binding site [nucleotide binding]; other site
762903000509	putative Zn2+ binding site [ion binding]; other site
762903000510	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
762903000511	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
762903000512	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
762903000513	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
762903000514	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
762903000515	Cl- selectivity filter; other site
762903000516	Cl- binding residues [ion binding]; other site
762903000517	pore gating glutamate residue; other site
762903000518	dimer interface [polypeptide binding]; other site
762903000519	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
762903000520	benzoate transport; Region: 2A0115; TIGR00895
762903000521	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903000522	putative substrate translocation pore; other site
762903000523	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; cl17557
762903000524	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
762903000525	putative efflux protein, MATE family; Region: matE; TIGR00797
762903000526	cation binding site [ion binding]; other site
762903000527	integral membrane protein; Region: integ_memb_HG; TIGR03954
762903000528	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
762903000529	active site
762903000530	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
762903000531	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
762903000532	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903000533	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903000534	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903000535	Outer membrane efflux protein; Region: OEP; pfam02321
762903000536	Outer membrane efflux protein; Region: OEP; pfam02321
762903000537	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903000538	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903000539	ligand binding site [chemical binding]; other site
762903000540	flexible hinge region; other site
762903000541	glycyl-tRNA synthetase; Provisional; Region: PRK04173
762903000542	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
762903000543	motif 1; other site
762903000544	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
762903000545	active site
762903000546	motif 2; other site
762903000547	motif 3; other site
762903000548	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
762903000549	anticodon binding site; other site
762903000550	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
762903000551	Clp amino terminal domain; Region: Clp_N; pfam02861
762903000552	Clp amino terminal domain; Region: Clp_N; pfam02861
762903000553	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903000554	Walker A motif; other site
762903000555	ATP binding site [chemical binding]; other site
762903000556	Walker B motif; other site
762903000557	arginine finger; other site
762903000558	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903000559	Walker A motif; other site
762903000560	ATP binding site [chemical binding]; other site
762903000561	Walker B motif; other site
762903000562	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
762903000563	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
762903000564	active site
762903000565	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
762903000566	nudix motif; other site
762903000567	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
762903000568	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
762903000569	active site
762903000570	(T/H)XGH motif; other site
762903000571	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
762903000572	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903000573	S-adenosylmethionine binding site [chemical binding]; other site
762903000574	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
762903000575	ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member [DNA replication, recombination, and repair]; Region: RecD; COG0507
762903000576	AAA domain; Region: AAA_30; pfam13604
762903000577	Family description; Region: UvrD_C_2; pfam13538
762903000578	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
762903000579	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
762903000580	tRNA; other site
762903000581	putative tRNA binding site [nucleotide binding]; other site
762903000582	putative NADP binding site [chemical binding]; other site
762903000583	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
762903000584	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
762903000585	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
762903000586	domain interfaces; other site
762903000587	active site
762903000588	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
762903000589	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
762903000590	active site
762903000591	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
762903000592	dimer interface [polypeptide binding]; other site
762903000593	allosteric magnesium binding site [ion binding]; other site
762903000594	active site
762903000595	aspartate-rich active site metal binding site; other site
762903000596	Schiff base residues; other site
762903000597	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
762903000598	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
762903000599	inhibitor-cofactor binding pocket; inhibition site
762903000600	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903000601	catalytic residue [active]
762903000602	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903000603	dimer interface [polypeptide binding]; other site
762903000604	phosphorylation site [posttranslational modification]
762903000605	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903000606	ATP binding site [chemical binding]; other site
762903000607	Mg2+ binding site [ion binding]; other site
762903000608	G-X-G motif; other site
762903000609	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903000610	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903000611	active site
762903000612	phosphorylation site [posttranslational modification]
762903000613	intermolecular recognition site; other site
762903000614	dimerization interface [polypeptide binding]; other site
762903000615	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
762903000616	DNA binding site [nucleotide binding]
762903000617	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
762903000618	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
762903000619	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
762903000620	substrate binding site [chemical binding]; other site
762903000621	active site
762903000622	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
762903000623	RNA polymerase sigma factor; Provisional; Region: PRK12513
762903000624	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903000625	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903000626	DNA binding residues [nucleotide binding]
762903000627	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
762903000628	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
762903000629	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
762903000630	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
762903000631	O-succinylhomoserine sulfhydrylase; Validated; Region: PRK08133
762903000632	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
762903000633	homodimer interface [polypeptide binding]; other site
762903000634	substrate-cofactor binding pocket; other site
762903000635	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903000636	catalytic residue [active]
762903000637	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
762903000638	Predicted transcriptional regulator [Transcription]; Region: COG1959
762903000639	Transcriptional regulator; Region: Rrf2; pfam02082
762903000640	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
762903000641	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
762903000642	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
762903000643	HEPN domain; Region: HEPN; cl00824
762903000644	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
762903000645	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
762903000646	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
762903000647	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
762903000648	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
762903000649	Active Sites [active]
762903000650	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
762903000651	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
762903000652	Active Sites [active]
762903000653	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
762903000654	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
762903000655	CysD dimerization site [polypeptide binding]; other site
762903000656	G1 box; other site
762903000657	putative GEF interaction site [polypeptide binding]; other site
762903000658	GTP/Mg2+ binding site [chemical binding]; other site
762903000659	Switch I region; other site
762903000660	G2 box; other site
762903000661	G3 box; other site
762903000662	Switch II region; other site
762903000663	G4 box; other site
762903000664	G5 box; other site
762903000665	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
762903000666	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
762903000667	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
762903000668	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
762903000669	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
762903000670	active site
762903000671	Riboflavin kinase; Region: Flavokinase; pfam01687
762903000672	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
762903000673	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
762903000674	RNA binding site [nucleotide binding]; other site
762903000675	active site
762903000676	Bacitracin resistance protein BacA; Region: BacA; pfam02673
762903000677	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
762903000678	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
762903000679	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
762903000680	leucyl-tRNA synthetase, eubacterial and mitochondrial family; Region: leuS_bact; TIGR00396
762903000681	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903000682	active site
762903000683	HIGH motif; other site
762903000684	nucleotide binding site [chemical binding]; other site
762903000685	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903000686	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
762903000687	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903000688	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903000689	active site
762903000690	KMSKS motif; other site
762903000691	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
762903000692	tRNA binding surface [nucleotide binding]; other site
762903000693	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903000694	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903000695	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903000696	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
762903000697	Predicted flavoprotein [General function prediction only]; Region: COG0431
762903000698	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
762903000699	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
762903000700	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
762903000701	P-loop; other site
762903000702	Magnesium ion binding site [ion binding]; other site
762903000703	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
762903000704	Magnesium ion binding site [ion binding]; other site
762903000705	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
762903000706	ParB-like nuclease domain; Region: ParBc; pfam02195
762903000707	dihydrodipicolinate reductase; Provisional; Region: PRK00048
762903000708	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
762903000709	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
762903000710	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
762903000711	Catalytic site [active]
762903000712	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
762903000713	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
762903000714	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
762903000715	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
762903000716	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
762903000717	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
762903000718	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903000719	FeS/SAM binding site; other site
762903000720	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
762903000721	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
762903000722	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
762903000723	Domain of unknown function (DUF4295); Region: DUF4295; pfam14128
762903000724	ribosomal protein L33; Region: rpl33; CHL00104
762903000725	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
762903000726	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
762903000727	Carbon starvation protein CstA; Region: CstA; pfam02554
762903000728	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
762903000729	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
762903000730	Homeodomain-like domain; Region: HTH_23; pfam13384
762903000731	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903000732	putative substrate translocation pore; other site
762903000733	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
762903000734	Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591
762903000735	Na binding site [ion binding]; other site
762903000736	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903000737	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903000738	dimer interface [polypeptide binding]; other site
762903000739	phosphorylation site [posttranslational modification]
762903000740	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903000741	ATP binding site [chemical binding]; other site
762903000742	Mg2+ binding site [ion binding]; other site
762903000743	G-X-G motif; other site
762903000744	Response regulator receiver domain; Region: Response_reg; pfam00072
762903000745	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903000746	active site
762903000747	phosphorylation site [posttranslational modification]
762903000748	intermolecular recognition site; other site
762903000749	dimerization interface [polypeptide binding]; other site
762903000750	acetyl-CoA synthetase; Provisional; Region: PRK00174
762903000751	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
762903000752	active site
762903000753	CoA binding site [chemical binding]; other site
762903000754	acyl-activating enzyme (AAE) consensus motif; other site
762903000755	AMP binding site [chemical binding]; other site
762903000756	acetate binding site [chemical binding]; other site
762903000757	CsbD-like; Region: CsbD; pfam05532
762903000758	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
762903000759	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
762903000760	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
762903000761	HTH domain; Region: HTH_11; pfam08279
762903000762	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903000763	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903000764	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903000765	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
762903000766	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
762903000767	Mg++ binding site [ion binding]; other site
762903000768	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
762903000769	Protein export membrane protein; Region: SecD_SecF; cl14618
762903000770	Protein export membrane protein; Region: SecD_SecF; cl14618
762903000771	Outer membrane efflux protein; Region: OEP; pfam02321
762903000772	Outer membrane efflux protein; Region: OEP; pfam02321
762903000773	O-Antigen ligase; Region: Wzy_C; cl04850
762903000774	O-Antigen ligase; Region: Wzy_C; pfam04932
762903000775	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
762903000776	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903000777	binding surface
762903000778	TPR motif; other site
762903000779	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
762903000780	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
762903000781	Catalytic site [active]
762903000782	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
762903000783	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
762903000784	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
762903000785	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
762903000786	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
762903000787	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903000788	putative substrate translocation pore; other site
762903000789	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903000790	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
762903000791	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903000792	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903000793	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903000794	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903000795	Di-glucose binding within endoplasmic reticulum; Region: Malectin; pfam11721
762903000796	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
762903000797	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903000798	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903000799	Protein of unknown function (DUF3826); Region: DUF3826; pfam12875
762903000800	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903000801	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903000802	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903000803	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903000804	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903000805	SusD family; Region: SusD; pfam07980
762903000806	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903000807	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903000808	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903000809	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903000810	SusD family; Region: SusD; pfam07980
762903000811	Pectate lyase; Region: Pec_lyase_C; cl01593
762903000812	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
762903000813	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
762903000814	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
762903000815	NAD binding site [chemical binding]; other site
762903000816	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
762903000817	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
762903000818	L-aspartate dehydrogenase; Reviewed; Region: PRK13304
762903000819	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
762903000820	Domain of unknown function DUF108; Region: DUF108; pfam01958
762903000821	Domain of unknown function (DUF4382); Region: DUF4382; pfam14321
762903000822	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903000823	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
762903000824	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903000825	Coenzyme A binding pocket [chemical binding]; other site
762903000826	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903000827	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903000828	Pectate lyase; Region: Pec_lyase_C; cl01593
762903000829	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
762903000830	Putative collagen-binding domain of a collagenase; Region: Collagen_bind_2; pfam12904
762903000831	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
762903000832	active site
762903000833	BNR repeat-like domain; Region: BNR_2; pfam13088
762903000834	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903000835	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903000836	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903000837	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903000838	Beta galactosidase small chain; Region: Bgal_small_N; cl03787
762903000839	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
762903000840	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
762903000841	Protein of unknown function (DUF3826); Region: DUF3826; pfam12875
762903000842	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
762903000843	catalytic site [active]
762903000844	BNR repeat-like domain; Region: BNR_2; pfam13088
762903000845	Asp-box motif; other site
762903000846	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
762903000847	5-hydroxyvalerate dehydrogenase (HVD) catalyzes the oxidation of 5-hydroxyvalerate to 5-oxovalerate with NAD+ as cofactor; Region: HVD; cd08193
762903000848	putative active site [active]
762903000849	metal binding site [ion binding]; metal-binding site
762903000850	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
762903000851	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
762903000852	inhibitor site; inhibition site
762903000853	active site
762903000854	dimer interface [polypeptide binding]; other site
762903000855	catalytic residue [active]
762903000856	Pyridoxal phosphate biosynthetic protein PdxA; Region: PdxA; cl00873
762903000857	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
762903000858	Protein of unknown function, DUF1537; Region: DUF1537; cl01345
762903000859	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
762903000860	Na binding site [ion binding]; other site
762903000861	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
762903000862	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
762903000863	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
762903000864	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
762903000865	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
762903000866	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903000867	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
762903000868	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903000869	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
762903000870	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
762903000871	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
762903000872	dimer interface [polypeptide binding]; other site
762903000873	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903000874	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
762903000875	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
762903000876	DNA binding residues [nucleotide binding]
762903000877	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
762903000878	Peptidase family M23; Region: Peptidase_M23; pfam01551
762903000879	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
762903000880	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
762903000881	Walker A/P-loop; other site
762903000882	ATP binding site [chemical binding]; other site
762903000883	Q-loop/lid; other site
762903000884	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
762903000885	Q-loop/lid; other site
762903000886	ABC transporter signature motif; other site
762903000887	Walker B; other site
762903000888	D-loop; other site
762903000889	H-loop/switch region; other site
762903000890	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
762903000891	Flavoprotein; Region: Flavoprotein; pfam02441
762903000892	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
762903000893	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; cl14651
762903000894	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
762903000895	Predicted membrane protein [Function unknown]; Region: COG1289
762903000896	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
762903000897	ribulokinase; Provisional; Region: PRK04123
762903000898	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
762903000899	N- and C-terminal domain interface [polypeptide binding]; other site
762903000900	active site
762903000901	MgATP binding site [chemical binding]; other site
762903000902	catalytic site [active]
762903000903	metal binding site [ion binding]; metal-binding site
762903000904	carbohydrate binding site [chemical binding]; other site
762903000905	homodimer interface [polypeptide binding]; other site
762903000906	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
762903000907	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
762903000908	intersubunit interface [polypeptide binding]; other site
762903000909	active site
762903000910	Zn2+ binding site [ion binding]; other site
762903000911	L-arabinose isomerase; Provisional; Region: PRK02929
762903000912	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
762903000913	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
762903000914	trimer interface [polypeptide binding]; other site
762903000915	putative substrate binding site [chemical binding]; other site
762903000916	putative metal binding site [ion binding]; other site
762903000917	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
762903000918	Peptidase S8 family domain in Subtilisin_Novo-like proteins; Region: Peptidases_S8_Subtilisin_Novo-like; cd07483
762903000919	active site
762903000920	catalytic triad [active]
762903000921	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
762903000922	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
762903000923	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
762903000924	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903000925	active site
762903000926	motif I; other site
762903000927	motif II; other site
762903000928	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903000929	Predicted membrane protein [Function unknown]; Region: COG2323
762903000930	Predicted permeases [General function prediction only]; Region: COG0795
762903000931	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
762903000932	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
762903000933	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
762903000934	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
762903000935	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
762903000936	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
762903000937	dimerization interface [polypeptide binding]; other site
762903000938	active site
762903000939	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
762903000940	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
762903000941	active site clefts [active]
762903000942	zinc binding site [ion binding]; other site
762903000943	dimer interface [polypeptide binding]; other site
762903000944	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
762903000945	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
762903000946	Sulfate transporter family; Region: Sulfate_transp; pfam00916
762903000947	putative bifunctional cbb3-type cytochrome c oxidase subunit I/II; Provisional; Region: PRK14485
762903000948	Cytochrome cbb3 oxidase subunit I.  Cytochrome cbb3 oxidase, the terminal oxidase in the respiratory chains of proteobacteria, is a multi-chain transmembrane protein located in the cell membrane. Like other cytochrome oxidases, it catalyzes the reduction...; Region: cbb3_Oxidase_I; cd01661
762903000949	Low-spin heme binding site [chemical binding]; other site
762903000950	Putative water exit pathway; other site
762903000951	Binuclear center (active site) [active]
762903000952	Putative proton exit pathway; other site
762903000953	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; pfam02433
762903000954	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
762903000955	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
762903000956	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
762903000957	4Fe-4S binding domain; Region: Fer4_5; pfam12801
762903000958	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
762903000959	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
762903000960	FixH; Region: FixH; pfam05751
762903000961	Family description; Region: DsbD_2; pfam13386
762903000962	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
762903000963	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903000964	FeS/SAM binding site; other site
762903000965	HemN C-terminal domain; Region: HemN_C; pfam06969
762903000966	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
762903000967	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
762903000968	putative ligand binding site [chemical binding]; other site
762903000969	putative NAD binding site [chemical binding]; other site
762903000970	catalytic site [active]
762903000971	Response regulator receiver domain; Region: Response_reg; pfam00072
762903000972	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903000973	active site
762903000974	phosphorylation site [posttranslational modification]
762903000975	intermolecular recognition site; other site
762903000976	dimerization interface [polypeptide binding]; other site
762903000977	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903000978	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903000979	ligand binding site [chemical binding]; other site
762903000980	flexible hinge region; other site
762903000981	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
762903000982	putative switch regulator; other site
762903000983	non-specific DNA interactions [nucleotide binding]; other site
762903000984	DNA binding site [nucleotide binding]
762903000985	sequence specific DNA binding site [nucleotide binding]; other site
762903000986	putative cAMP binding site [chemical binding]; other site
762903000987	PAS domain; Region: PAS_9; pfam13426
762903000988	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903000989	putative active site [active]
762903000990	heme pocket [chemical binding]; other site
762903000991	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903000992	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903000993	dimer interface [polypeptide binding]; other site
762903000994	phosphorylation site [posttranslational modification]
762903000995	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903000996	ATP binding site [chemical binding]; other site
762903000997	Mg2+ binding site [ion binding]; other site
762903000998	G-X-G motif; other site
762903000999	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532
762903001000	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903001001	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903001002	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
762903001003	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
762903001004	DNA binding site [nucleotide binding]
762903001005	active site
762903001006	Domain of unknown function (DUF1508); Region: DUF1508; cl01356
762903001007	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
762903001008	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09560
762903001009	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
762903001010	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
762903001011	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
762903001012	putative dimer interface [polypeptide binding]; other site
762903001013	putative anticodon binding site; other site
762903001014	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
762903001015	homodimer interface [polypeptide binding]; other site
762903001016	motif 1; other site
762903001017	motif 2; other site
762903001018	active site
762903001019	motif 3; other site
762903001020	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
762903001021	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903001022	S-adenosylmethionine binding site [chemical binding]; other site
762903001023	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
762903001024	active site
762903001025	metal binding site [ion binding]; metal-binding site
762903001026	homotetramer interface [polypeptide binding]; other site
762903001027	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
762903001028	AMP binding site [chemical binding]; other site
762903001029	metal binding site [ion binding]; metal-binding site
762903001030	active site
762903001031	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
762903001032	RNA/DNA hybrid binding site [nucleotide binding]; other site
762903001033	active site
762903001034	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903001035	Coenzyme A binding pocket [chemical binding]; other site
762903001036	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
762903001037	Inner membrane protein CreD; Region: CreD; pfam06123
762903001038	Transcriptional regulators [Transcription]; Region: MarR; COG1846
762903001039	Winged helix DNA-binding domain; Region: HTH_34; pfam13601
762903001040	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
762903001041	AAA domain; Region: AAA_33; pfam13671
762903001042	ATP-binding site [chemical binding]; other site
762903001043	Gluconate-6-phosphate binding site [chemical binding]; other site
762903001044	GtrA-like protein; Region: GtrA; pfam04138
762903001045	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
762903001046	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
762903001047	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
762903001048	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
762903001049	Amidohydrolase family; Region: Amidohydro_1; pfam01979
762903001050	DEAD-like helicases superfamily; Region: DEXDc; smart00487
762903001051	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903001052	ATP binding site [chemical binding]; other site
762903001053	putative Mg++ binding site [ion binding]; other site
762903001054	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903001055	nucleotide binding region [chemical binding]; other site
762903001056	ATP-binding site [chemical binding]; other site
762903001057	Transposase IS200 like; Region: Y1_Tnp; cl00848
762903001058	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
762903001059	DEAD-like helicases superfamily; Region: DEXDc; smart00487
762903001060	ATP binding site [chemical binding]; other site
762903001061	Mg++ binding site [ion binding]; other site
762903001062	motif III; other site
762903001063	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903001064	nucleotide binding region [chemical binding]; other site
762903001065	ATP-binding site [chemical binding]; other site
762903001066	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
762903001067	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
762903001068	active site
762903001069	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
762903001070	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
762903001071	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
762903001072	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_like; cd07021
762903001073	dimer interface [polypeptide binding]; other site
762903001074	active site residues [active]
762903001075	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
762903001076	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
762903001077	dimerization interface [polypeptide binding]; other site
762903001078	DPS ferroxidase diiron center [ion binding]; other site
762903001079	ion pore; other site
762903001080	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
762903001081	putative active site [active]
762903001082	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
762903001083	prolyl-tRNA synthetase; Provisional; Region: PRK08661
762903001084	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
762903001085	dimer interface [polypeptide binding]; other site
762903001086	motif 1; other site
762903001087	active site
762903001088	motif 2; other site
762903001089	motif 3; other site
762903001090	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
762903001091	anticodon binding site; other site
762903001092	zinc-binding site [ion binding]; other site
762903001093	Glycosyl hydrolase 43-like family consists of hypothetical proteins; Region: GH43_like_2; cd08994
762903001094	active site
762903001095	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
762903001096	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
762903001097	active site
762903001098	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
762903001099	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
762903001100	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
762903001101	Vacuole effluxer Atg22 like; Region: ATG22; pfam11700
762903001102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903001103	putative substrate translocation pore; other site
762903001104	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
762903001105	Cysteine-rich domain; Region: CCG; pfam02754
762903001106	Cysteine-rich domain; Region: CCG; pfam02754
762903001107	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903001108	binding surface
762903001109	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903001110	TPR motif; other site
762903001111	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903001112	binding surface
762903001113	TPR motif; other site
762903001114	Ribosomal protein L17; Region: Ribosomal_L17; cl00356
762903001115	CHAT domain; Region: CHAT; pfam12770
762903001116	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
762903001117	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
762903001118	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
762903001119	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
762903001120	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
762903001121	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
762903001122	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
762903001123	active site
762903001124	dimer interface [polypeptide binding]; other site
762903001125	motif 1; other site
762903001126	motif 2; other site
762903001127	motif 3; other site
762903001128	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
762903001129	anticodon binding site; other site
762903001130	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
762903001131	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
762903001132	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
762903001133	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
762903001134	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
762903001135	23S rRNA binding site [nucleotide binding]; other site
762903001136	L21 binding site [polypeptide binding]; other site
762903001137	L13 binding site [polypeptide binding]; other site
762903001138	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
762903001139	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
762903001140	dimer interface [polypeptide binding]; other site
762903001141	decamer (pentamer of dimers) interface [polypeptide binding]; other site
762903001142	catalytic triad [active]
762903001143	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
762903001144	Domain of unknown function DUF20; Region: UPF0118; pfam01594
762903001145	RNA polymerase sigma factor, cyanobacterial RpoD-like family; Region: Sig70-cyanoRpoD; TIGR02997
762903001146	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
762903001147	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903001148	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
762903001149	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903001150	DNA binding residues [nucleotide binding]
762903001151	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
762903001152	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
762903001153	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
762903001154	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
762903001155	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
762903001156	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903001157	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
762903001158	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903001159	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
762903001160	Cytochrome c; Region: Cytochrom_C; pfam00034
762903001161	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
762903001162	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
762903001163	Asp-box motif; other site
762903001164	Polysaccharide lyase; Region: Polysacc_lyase; pfam14099
762903001165	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
762903001166	active site
762903001167	catalytic triad [active]
762903001168	oxyanion hole [active]
762903001169	Predicted acyl esterases [General function prediction only]; Region: COG2936
762903001170	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
762903001171	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
762903001172	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
762903001173	Walker A/P-loop; other site
762903001174	ATP binding site [chemical binding]; other site
762903001175	Q-loop/lid; other site
762903001176	ABC transporter signature motif; other site
762903001177	Walker B; other site
762903001178	D-loop; other site
762903001179	H-loop/switch region; other site
762903001180	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
762903001181	dimer interface [polypeptide binding]; other site
762903001182	conserved gate region; other site
762903001183	ABC-ATPase subunit interface; other site
762903001184	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
762903001185	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
762903001186	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
762903001187	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
762903001188	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
762903001189	N-terminal plug; other site
762903001190	ligand-binding site [chemical binding]; other site
762903001191	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903001192	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903001193	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903001194	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903001195	dimer interface [polypeptide binding]; other site
762903001196	phosphorylation site [posttranslational modification]
762903001197	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903001198	ATP binding site [chemical binding]; other site
762903001199	Mg2+ binding site [ion binding]; other site
762903001200	G-X-G motif; other site
762903001201	Response regulator receiver domain; Region: Response_reg; pfam00072
762903001202	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903001203	active site
762903001204	phosphorylation site [posttranslational modification]
762903001205	intermolecular recognition site; other site
762903001206	dimerization interface [polypeptide binding]; other site
762903001207	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903001208	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903001209	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903001210	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903001211	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903001212	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903001213	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903001214	Fibronectin type 3 domain; Region: FN3; smart00060
762903001215	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
762903001216	Pectate lyase; Region: Pec_lyase_C; cl01593
762903001217	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903001218	Bacterial Ig-like domain; Region: Big_5; pfam13205
762903001219	putative pectinesterase; Region: PLN02432; cl01911
762903001220	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903001221	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
762903001222	PA14 domain; Region: PA14; cl08459
762903001223	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
762903001224	Pectinesterase; Region: Pectinesterase; pfam01095
762903001225	putative pectinesterase; Region: PLN02432; cl01911
762903001226	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
762903001227	NAD-dependent deacetylase; Provisional; Region: PRK00481
762903001228	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
762903001229	NAD+ binding site [chemical binding]; other site
762903001230	substrate binding site [chemical binding]; other site
762903001231	Zn binding site [ion binding]; other site
762903001232	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
762903001233	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
762903001234	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903001235	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903001236	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903001237	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
762903001238	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
762903001239	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
762903001240	CoA-transferase family III; Region: CoA_transf_3; pfam02515
762903001241	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
762903001242	CoA-transferase family III; Region: CoA_transf_3; pfam02515
762903001243	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
762903001244	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
762903001245	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
762903001246	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903001247	NAD(P) binding pocket [chemical binding]; other site
762903001248	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
762903001249	active site 2 [active]
762903001250	active site 1 [active]
762903001251	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
762903001252	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
762903001253	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
762903001254	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903001255	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903001256	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903001257	ligand binding site [chemical binding]; other site
762903001258	flexible hinge region; other site
762903001259	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
762903001260	Uncharacterized conserved protein [Function unknown]; Region: COG2128
762903001261	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
762903001262	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
762903001263	putative NAD(P) binding site [chemical binding]; other site
762903001264	catalytic Zn binding site [ion binding]; other site
762903001265	structural Zn binding site [ion binding]; other site
762903001266	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
762903001267	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
762903001268	active site
762903001269	catalytic tetrad [active]
762903001270	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
762903001271	Amidohydrolase; Region: Amidohydro_2; pfam04909
762903001272	active site
762903001273	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
762903001274	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
762903001275	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
762903001276	classical (c) SDRs; Region: SDR_c; cd05233
762903001277	NAD(P) binding site [chemical binding]; other site
762903001278	active site
762903001279	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
762903001280	galactarate dehydratase; Region: galactar-dH20; TIGR03248
762903001281	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
762903001282	Transcriptional regulator [Transcription]; Region: IclR; COG1414
762903001283	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
762903001284	Bacterial transcriptional regulator; Region: IclR; pfam01614
762903001285	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
762903001286	Mechanosensitive ion channel; Region: MS_channel; pfam00924
762903001287	Domain of unknown function (DUF4268); Region: DUF4268; pfam14088
762903001288	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
762903001289	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
762903001290	active site
762903001291	Uncharacterized conserved protein [Function unknown]; Region: COG1262
762903001292	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
762903001293	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_6; cd06154
762903001294	homotrimer interaction site [polypeptide binding]; other site
762903001295	putative active site [active]
762903001296	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903001297	Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408
762903001298	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
762903001299	Melibiase; Region: Melibiase; pfam02065
762903001300	Peptidase S46; Region: Peptidase_S46; pfam10459
762903001301	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
762903001302	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
762903001303	active site
762903001304	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903001305	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
762903001306	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
762903001307	GatB domain; Region: GatB_Yqey; smart00845
762903001308	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
762903001309	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
762903001310	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903001311	catalytic residues [active]
762903001312	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903001313	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903001314	active site
762903001315	phosphorylation site [posttranslational modification]
762903001316	intermolecular recognition site; other site
762903001317	dimerization interface [polypeptide binding]; other site
762903001318	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
762903001319	DNA binding site [nucleotide binding]
762903001320	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
762903001321	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
762903001322	active site
762903001323	Alginate lyase; Region: Alginate_lyase; pfam05426
762903001324	O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315
762903001325	Leucine carboxyl methyltransferase; Region: LCM; pfam04072
762903001326	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903001327	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
762903001328	dimer interface [polypeptide binding]; other site
762903001329	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
762903001330	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903001331	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903001332	ABC transporter; Region: ABC_tran_2; pfam12848
762903001333	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903001334	H+ Antiporter protein; Region: 2A0121; TIGR00900
762903001335	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903001336	putative substrate translocation pore; other site
762903001337	DinB family; Region: DinB; cl17821
762903001338	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903001339	TonB-dependent vitamin B12 receptor; Region: TonB-B12; TIGR01779
762903001340	Uncharacterized conserved protein [Function unknown]; Region: COG3391
762903001341	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK02862
762903001342	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
762903001343	ligand binding site; other site
762903001344	oligomer interface; other site
762903001345	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
762903001346	dimer interface [polypeptide binding]; other site
762903001347	N-terminal domain interface [polypeptide binding]; other site
762903001348	sulfate 1 binding site; other site
762903001349	glycogen synthase; Provisional; Region: glgA; PRK00654
762903001350	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
762903001351	ADP-binding pocket [chemical binding]; other site
762903001352	homodimer interface [polypeptide binding]; other site
762903001353	glycogen branching enzyme; Provisional; Region: PRK12313
762903001354	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
762903001355	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
762903001356	active site
762903001357	catalytic site [active]
762903001358	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
762903001359	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
762903001360	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
762903001361	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
762903001362	trimer interface [polypeptide binding]; other site
762903001363	active site
762903001364	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
762903001365	catalytic site [active]
762903001366	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903001367	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903001368	ligand binding site [chemical binding]; other site
762903001369	flexible hinge region; other site
762903001370	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
762903001371	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
762903001372	active site
762903001373	intersubunit interface [polypeptide binding]; other site
762903001374	catalytic residue [active]
762903001375	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
762903001376	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903001377	Coenzyme A binding pocket [chemical binding]; other site
762903001378	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
762903001379	Transposase IS200 like; Region: Y1_Tnp; cl00848
762903001380	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
762903001381	active site
762903001382	catalytic site [active]
762903001383	substrate binding site [chemical binding]; other site
762903001384	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903001385	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903001386	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903001387	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
762903001388	active site
762903001389	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
762903001390	Predicted ATPase [General function prediction only]; Region: COG3911
762903001391	AAA domain; Region: AAA_28; pfam13521
762903001392	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
762903001393	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
762903001394	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903001395	catalytic residue [active]
762903001396	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
762903001397	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
762903001398	Uncharacterized conserved protein (COG2071); Region: DUF2071; cl01329
762903001399	A new structural DNA glycosylase; Region: AlkD_like; cd06561
762903001400	active site
762903001401	Mechanosensitive ion channel; Region: MS_channel; pfam00924
762903001402	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
762903001403	dimer interface [polypeptide binding]; other site
762903001404	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903001405	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
762903001406	active site
762903001407	catalytic residues [active]
762903001408	DNA binding site [nucleotide binding]
762903001409	Int/Topo IB signature motif; other site
762903001410	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
762903001411	MPN+ (JAMM) motif; other site
762903001412	Zinc-binding site [ion binding]; other site
762903001413	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
762903001414	RNA binding site [nucleotide binding]; other site
762903001415	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
762903001416	RNA binding site [nucleotide binding]; other site
762903001417	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
762903001418	RNA binding site [nucleotide binding]; other site
762903001419	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
762903001420	RNA binding site [nucleotide binding]; other site
762903001421	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
762903001422	Predicted NTPase (NACHT family) [Signal transduction mechanisms]; Region: COG5635
762903001423	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
762903001424	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
762903001425	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
762903001426	active site
762903001427	metal binding site [ion binding]; metal-binding site
762903001428	DNA binding site [nucleotide binding]
762903001429	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
762903001430	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
762903001431	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903001432	Walker A/P-loop; other site
762903001433	ATP binding site [chemical binding]; other site
762903001434	Q-loop/lid; other site
762903001435	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903001436	ABC transporter signature motif; other site
762903001437	Walker B; other site
762903001438	D-loop; other site
762903001439	H-loop/switch region; other site
762903001440	Competence-damaged protein; Region: CinA; pfam02464
762903001441	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903001442	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903001443	DNA binding site [nucleotide binding]
762903001444	domain linker motif; other site
762903001445	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903001446	dimerization interface [polypeptide binding]; other site
762903001447	ligand binding site [chemical binding]; other site
762903001448	D-mannonate oxidoreductase; Provisional; Region: PRK08277
762903001449	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903001450	NAD(P) binding site [chemical binding]; other site
762903001451	active site
762903001452	mannonate dehydratase; Provisional; Region: PRK03906
762903001453	mannonate dehydratase; Region: uxuA; TIGR00695
762903001454	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
762903001455	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
762903001456	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
762903001457	active site
762903001458	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
762903001459	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
762903001460	Transposase; Region: DEDD_Tnp_IS110; pfam01548
762903001461	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
762903001462	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
762903001463	Transposase; Region: DEDD_Tnp_IS110; pfam01548
762903001464	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
762903001465	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
762903001466	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
762903001467	active site
762903001468	DNA binding site [nucleotide binding]
762903001469	Int/Topo IB signature motif; other site
762903001470	MerT mercuric transport protein; Region: MerT; cl03578
762903001471	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
762903001472	metal-binding site [ion binding]
762903001473	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
762903001474	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
762903001475	Domain of unknown function (DUF4365); Region: DUF4365; pfam14280
762903001476	TPR repeat; Region: TPR_11; pfam13414
762903001477	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903001478	binding surface
762903001479	TPR motif; other site
762903001480	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903001481	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903001482	binding surface
762903001483	TPR motif; other site
762903001484	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
762903001485	dimerization interface [polypeptide binding]; other site
762903001486	putative DNA binding site [nucleotide binding]; other site
762903001487	putative Zn2+ binding site [ion binding]; other site
762903001488	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
762903001489	Low molecular weight phosphatase family; Region: LMWPc; cd00115
762903001490	active site
762903001491	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903001492	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903001493	ligand binding site [chemical binding]; other site
762903001494	flexible hinge region; other site
762903001495	Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs; Region: carb_red_PTCR-like_SDR_c; cd05324
762903001496	short chain dehydrogenase; Provisional; Region: PRK06198
762903001497	NADP binding site [chemical binding]; other site
762903001498	substrate binding site [chemical binding]; other site
762903001499	active site
762903001500	TQO small subunit DoxD; Region: DoxD; pfam04173
762903001501	TQO small subunit DoxA; Region: DoxA; pfam07680
762903001502	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_7; cd08353
762903001503	putative dimer interface [polypeptide binding]; other site
762903001504	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903001505	Coenzyme A binding pocket [chemical binding]; other site
762903001506	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
762903001507	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
762903001508	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
762903001509	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
762903001510	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903001511	motif II; other site
762903001512	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
762903001513	Protein of unknown function (DUF2945); Region: DUF2945; pfam11160
762903001514	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903001515	TPR motif; other site
762903001516	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903001517	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
762903001518	DXD motif; other site
762903001519	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
762903001520	Sulfatase; Region: Sulfatase; cl17466
762903001521	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903001522	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903001523	active site
762903001524	phosphorylation site [posttranslational modification]
762903001525	intermolecular recognition site; other site
762903001526	dimerization interface [polypeptide binding]; other site
762903001527	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
762903001528	GAF domain; Region: GAF; pfam01590
762903001529	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903001530	putative active site [active]
762903001531	heme pocket [chemical binding]; other site
762903001532	PAS domain S-box; Region: sensory_box; TIGR00229
762903001533	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903001534	putative active site [active]
762903001535	heme pocket [chemical binding]; other site
762903001536	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903001537	PAS fold; Region: PAS_3; pfam08447
762903001538	putative active site [active]
762903001539	heme pocket [chemical binding]; other site
762903001540	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
762903001541	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903001542	dimer interface [polypeptide binding]; other site
762903001543	phosphorylation site [posttranslational modification]
762903001544	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903001545	ATP binding site [chemical binding]; other site
762903001546	Mg2+ binding site [ion binding]; other site
762903001547	G-X-G motif; other site
762903001548	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903001549	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903001550	active site
762903001551	phosphorylation site [posttranslational modification]
762903001552	intermolecular recognition site; other site
762903001553	dimerization interface [polypeptide binding]; other site
762903001554	Response regulator receiver domain; Region: Response_reg; pfam00072
762903001555	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903001556	active site
762903001557	phosphorylation site [posttranslational modification]
762903001558	intermolecular recognition site; other site
762903001559	dimerization interface [polypeptide binding]; other site
762903001560	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
762903001561	putative binding surface; other site
762903001562	active site
762903001563	5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt; cl00231
762903001564	ATP binding site [chemical binding]; other site
762903001565	active site
762903001566	substrate binding site [chemical binding]; other site
762903001567	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
762903001568	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903001569	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903001570	ligand binding site [chemical binding]; other site
762903001571	flexible hinge region; other site
762903001572	Pirin-related protein [General function prediction only]; Region: COG1741
762903001573	Pirin; Region: Pirin; pfam02678
762903001574	Uncharacterized conserved protein [Function unknown]; Region: COG2353
762903001575	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
762903001576	von Willebrand factor type A domain; Region: VWA_2; pfam13519
762903001577	dihydroorotase; Validated; Region: pyrC; PRK09357
762903001578	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
762903001579	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
762903001580	active site
762903001581	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
762903001582	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
762903001583	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
762903001584	Ligand binding site; other site
762903001585	Putative Catalytic site; other site
762903001586	DXD motif; other site
762903001587	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
762903001588	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903001589	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903001590	active site
762903001591	GH3 auxin-responsive promoter; Region: GH3; pfam03321
762903001592	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
762903001593	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
762903001594	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
762903001595	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
762903001596	RIP metalloprotease RseP; Region: TIGR00054
762903001597	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
762903001598	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
762903001599	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
762903001600	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
762903001601	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
762903001602	HSP70 interaction site [polypeptide binding]; other site
762903001603	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
762903001604	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
762903001605	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
762903001606	NADP binding site [chemical binding]; other site
762903001607	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
762903001608	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
762903001609	Ligand binding site; other site
762903001610	oligomer interface; other site
762903001611	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
762903001612	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
762903001613	Substrate-binding site [chemical binding]; other site
762903001614	Substrate specificity [chemical binding]; other site
762903001615	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
762903001616	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
762903001617	active site
762903001618	HIGH motif; other site
762903001619	dimer interface [polypeptide binding]; other site
762903001620	KMSKS motif; other site
762903001621	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
762903001622	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
762903001623	putative acyl-acceptor binding pocket; other site
762903001624	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
762903001625	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
762903001626	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
762903001627	Walker A/P-loop; other site
762903001628	ATP binding site [chemical binding]; other site
762903001629	Q-loop/lid; other site
762903001630	ABC transporter signature motif; other site
762903001631	Walker B; other site
762903001632	D-loop; other site
762903001633	H-loop/switch region; other site
762903001634	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
762903001635	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
762903001636	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903001637	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903001638	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903001639	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903001640	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903001641	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
762903001642	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
762903001643	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903001644	putative substrate translocation pore; other site
762903001645	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
762903001646	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
762903001647	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903001648	putative metal binding site [ion binding]; other site
762903001649	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
762903001650	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
762903001651	dimer interface [polypeptide binding]; other site
762903001652	active site
762903001653	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
762903001654	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
762903001655	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
762903001656	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
762903001657	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
762903001658	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903001659	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903001660	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
762903001661	dimer interface [polypeptide binding]; other site
762903001662	Citrate synthase; Region: Citrate_synt; pfam00285
762903001663	active site
762903001664	citrylCoA binding site [chemical binding]; other site
762903001665	NADH binding [chemical binding]; other site
762903001666	cationic pore residues; other site
762903001667	oxalacetate/citrate binding site [chemical binding]; other site
762903001668	coenzyme A binding site [chemical binding]; other site
762903001669	catalytic triad [active]
762903001670	RibD C-terminal domain; Region: RibD_C; cl17279
762903001671	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
762903001672	Active_site [active]
762903001673	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
762903001674	classical (c) SDRs; Region: SDR_c; cd05233
762903001675	NAD(P) binding site [chemical binding]; other site
762903001676	active site
762903001677	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
762903001678	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
762903001679	dimerization interface [polypeptide binding]; other site
762903001680	ligand binding site [chemical binding]; other site
762903001681	NADP binding site [chemical binding]; other site
762903001682	catalytic site [active]
762903001683	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
762903001684	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
762903001685	Tetramer interface [polypeptide binding]; other site
762903001686	active site
762903001687	FMN-binding site [chemical binding]; other site
762903001688	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
762903001689	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
762903001690	putative active site [active]
762903001691	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
762903001692	Chorismate mutase type II; Region: CM_2; smart00830
762903001693	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
762903001694	Prephenate dehydratase; Region: PDT; pfam00800
762903001695	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
762903001696	putative L-Phe binding site [chemical binding]; other site
762903001697	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
762903001698	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
762903001699	Metal-binding active site; metal-binding site
762903001700	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903001701	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903001702	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903001703	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903001704	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903001705	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903001706	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903001707	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
762903001708	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
762903001709	RNA binding surface [nucleotide binding]; other site
762903001710	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
762903001711	probable active site [active]
762903001712	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
762903001713	EamA-like transporter family; Region: EamA; pfam00892
762903001714	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
762903001715	Smr domain; Region: Smr; pfam01713
762903001716	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
762903001717	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
762903001718	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
762903001719	Maf-like protein; Region: Maf; pfam02545
762903001720	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
762903001721	active site
762903001722	dimer interface [polypeptide binding]; other site
762903001723	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903001724	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
762903001725	NAD(P) binding site [chemical binding]; other site
762903001726	active site
762903001727	Phosphopantetheine attachment site; Region: PP-binding; cl09936
762903001728	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
762903001729	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
762903001730	dimer interface [polypeptide binding]; other site
762903001731	active site
762903001732	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
762903001733	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903001734	NAD(P) binding site [chemical binding]; other site
762903001735	active site
762903001736	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
762903001737	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
762903001738	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
762903001739	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cd06551
762903001740	putative acyl-acceptor binding pocket; other site
762903001741	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903001742	Protein of unknown function (DUF3347); Region: DUF3347; pfam11827
762903001743	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903001744	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903001745	HlyD family secretion protein; Region: HlyD_2; pfam12700
762903001746	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903001747	Outer membrane efflux protein; Region: OEP; pfam02321
762903001748	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
762903001749	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
762903001750	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903001751	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903001752	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903001753	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903001754	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903001755	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903001756	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903001757	SusD family; Region: SusD; pfam07980
762903001758	Heparinase II/III-like protein; Region: Hepar_II_III; cl15421
762903001759	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
762903001760	dimerization interface [polypeptide binding]; other site
762903001761	putative active cleft [active]
762903001762	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u1; cd11477
762903001763	Na binding site [ion binding]; other site
762903001764	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
762903001765	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
762903001766	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
762903001767	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
762903001768	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903001769	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903001770	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903001771	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903001772	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903001773	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903001774	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903001775	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903001776	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903001777	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903001778	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903001779	SusD family; Region: SusD; pfam07980
762903001780	SusD family; Region: SusD; pfam07980
762903001781	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903001782	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903001783	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
762903001784	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903001785	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
762903001786	active site
762903001787	catalytic triad [active]
762903001788	oxyanion hole [active]
762903001789	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903001790	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903001791	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
762903001792	N-terminal plug; other site
762903001793	ligand-binding site [chemical binding]; other site
762903001794	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
762903001795	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
762903001796	metal binding site [ion binding]; metal-binding site
762903001797	substrate binding pocket [chemical binding]; other site
762903001798	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
762903001799	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
762903001800	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
762903001801	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
762903001802	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903001803	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
762903001804	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903001805	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903001806	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903001807	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903001808	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903001809	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903001810	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903001811	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903001812	SusD family; Region: SusD; pfam07980
762903001813	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
762903001814	Periplasmic copper-binding protein (NosD); Region: NosD; pfam05048
762903001815	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903001816	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
762903001817	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
762903001818	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
762903001819	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903001820	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
762903001821	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
762903001822	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
762903001823	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
762903001824	Cytochrome c; Region: Cytochrom_C; pfam00034
762903001825	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
762903001826	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
762903001827	gluconate 5-dehydrogenase; Provisional; Region: PRK08213
762903001828	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
762903001829	Class I aldolases; Region: Aldolase_Class_I; cl17187
762903001830	catalytic residue [active]
762903001831	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
762903001832	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903001833	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
762903001834	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
762903001835	active site
762903001836	dimer interface [polypeptide binding]; other site
762903001837	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
762903001838	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
762903001839	active site
762903001840	trimer interface [polypeptide binding]; other site
762903001841	allosteric site; other site
762903001842	active site lid [active]
762903001843	hexamer (dimer of trimers) interface [polypeptide binding]; other site
762903001844	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903001845	DNA binding site [nucleotide binding]
762903001846	domain linker motif; other site
762903001847	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
762903001848	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
762903001849	ligand binding site [chemical binding]; other site
762903001850	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903001851	DNA binding site [nucleotide binding]
762903001852	domain linker motif; other site
762903001853	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
762903001854	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
762903001855	ligand binding site [chemical binding]; other site
762903001856	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
762903001857	putative ligand binding site [chemical binding]; other site
762903001858	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903001859	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903001860	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903001861	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903001862	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903001863	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903001864	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
762903001865	L-fucose transporter; Provisional; Region: PRK10133; cl17665
762903001866	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
762903001867	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
762903001868	substrate binding pocket [chemical binding]; other site
762903001869	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903001870	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903001871	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903001872	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903001873	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
762903001874	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
762903001875	Heavy-metal-associated domain; Region: HMA; pfam00403
762903001876	metal-binding site [ion binding]
762903001877	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
762903001878	Soluble P-type ATPase [General function prediction only]; Region: COG4087
762903001879	Cytochrome oxidase maturation protein cbb3-type; Region: CcoS; pfam03597
762903001880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903001881	Major Facilitator Superfamily; Region: MFS_1; pfam07690
762903001882	putative substrate translocation pore; other site
762903001883	Transcriptional regulators [Transcription]; Region: FadR; COG2186
762903001884	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
762903001885	DNA-binding site [nucleotide binding]; DNA binding site
762903001886	FCD domain; Region: FCD; pfam07729
762903001887	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
762903001888	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
762903001889	Protein of unknown function (DUF3307); Region: DUF3307; pfam11750
762903001890	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
762903001891	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
762903001892	Beta-Casp domain; Region: Beta-Casp; smart01027
762903001893	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
762903001894	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
762903001895	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
762903001896	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
762903001897	Walker A/P-loop; other site
762903001898	ATP binding site [chemical binding]; other site
762903001899	Q-loop/lid; other site
762903001900	ABC transporter signature motif; other site
762903001901	Walker B; other site
762903001902	D-loop; other site
762903001903	H-loop/switch region; other site
762903001904	aspartate aminotransferase; Provisional; Region: PRK05764
762903001905	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
762903001906	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903001907	homodimer interface [polypeptide binding]; other site
762903001908	catalytic residue [active]
762903001909	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
762903001910	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
762903001911	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
762903001912	nudix motif; other site
762903001913	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
762903001914	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
762903001915	gamma-glutamyl kinase; Provisional; Region: PRK05429
762903001916	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
762903001917	nucleotide binding site [chemical binding]; other site
762903001918	homotetrameric interface [polypeptide binding]; other site
762903001919	putative phosphate binding site [ion binding]; other site
762903001920	putative allosteric binding site; other site
762903001921	PUA domain; Region: PUA; pfam01472
762903001922	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
762903001923	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
762903001924	putative catalytic cysteine [active]
762903001925	Predicted flavoprotein [General function prediction only]; Region: COG0431
762903001926	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
762903001927	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
762903001928	dimer interface [polypeptide binding]; other site
762903001929	active site
762903001930	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
762903001931	catalytic residues [active]
762903001932	substrate binding site [chemical binding]; other site
762903001933	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
762903001934	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
762903001935	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903001936	active site
762903001937	HIGH motif; other site
762903001938	nucleotide binding site [chemical binding]; other site
762903001939	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
762903001940	KMSK motif region; other site
762903001941	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
762903001942	tRNA binding surface [nucleotide binding]; other site
762903001943	anticodon binding site; other site
762903001944	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
762903001945	Na binding site [ion binding]; other site
762903001946	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
762903001947	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
762903001948	inhibitor site; inhibition site
762903001949	active site
762903001950	dimer interface [polypeptide binding]; other site
762903001951	catalytic residue [active]
762903001952	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
762903001953	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
762903001954	Nucleoside recognition; Region: Gate; pfam07670
762903001955	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
762903001956	Bifunctional nuclease; Region: DNase-RNase; pfam02577
762903001957	UvrB/uvrC motif; Region: UVR; pfam02151
762903001958	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
762903001959	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
762903001960	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
762903001961	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
762903001962	Ligand binding site [chemical binding]; other site
762903001963	Electron transfer flavoprotein domain; Region: ETF; pfam01012
762903001964	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903001965	TPR motif; other site
762903001966	TPR repeat; Region: TPR_11; pfam13414
762903001967	binding surface
762903001968	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
762903001969	Chromate transporter; Region: Chromate_transp; pfam02417
762903001970	Chromate transporter; Region: Chromate_transp; pfam02417
762903001971	replicative DNA helicase; Region: DnaB; TIGR00665
762903001972	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
762903001973	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
762903001974	Walker A motif; other site
762903001975	ATP binding site [chemical binding]; other site
762903001976	Walker B motif; other site
762903001977	DNA binding loops [nucleotide binding]
762903001978	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
762903001979	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
762903001980	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
762903001981	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
762903001982	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
762903001983	active site
762903001984	interdomain interaction site; other site
762903001985	putative metal-binding site [ion binding]; other site
762903001986	nucleotide binding site [chemical binding]; other site
762903001987	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
762903001988	domain I; other site
762903001989	DNA binding groove [nucleotide binding]
762903001990	phosphate binding site [ion binding]; other site
762903001991	domain II; other site
762903001992	domain III; other site
762903001993	nucleotide binding site [chemical binding]; other site
762903001994	catalytic site [active]
762903001995	domain IV; other site
762903001996	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
762903001997	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
762903001998	PspC domain; Region: PspC; pfam04024
762903001999	Predicted transcriptional regulators [Transcription]; Region: COG1695
762903002000	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
762903002001	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
762903002002	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
762903002003	Ligand Binding Site [chemical binding]; other site
762903002004	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
762903002005	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
762903002006	NAD(P) binding site [chemical binding]; other site
762903002007	catalytic residues [active]
762903002008	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_1; cd08894
762903002009	putative hydrophobic ligand binding site [chemical binding]; other site
762903002010	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
762903002011	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
762903002012	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903002013	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903002014	ABC transporter; Region: ABC_tran_2; pfam12848
762903002015	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903002016	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903002017	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903002018	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903002019	DNA binding residues [nucleotide binding]
762903002020	FecR protein; Region: FecR; pfam04773
762903002021	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903002022	Secretin and TonB N terminus short domain; Region: STN; pfam07660
762903002023	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903002024	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903002025	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903002026	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903002027	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903002028	SusD family; Region: SusD; pfam07980
762903002029	Uncharacterized conserved protein [Function unknown]; Region: COG1262
762903002030	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
762903002031	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903002032	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903002033	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903002034	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903002035	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903002036	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903002037	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903002038	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903002039	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903002040	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
762903002041	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903002042	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903002043	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903002044	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903002045	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903002046	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
762903002047	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903002048	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
762903002049	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903002050	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903002051	DNA binding site [nucleotide binding]
762903002052	domain linker motif; other site
762903002053	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903002054	ligand binding site [chemical binding]; other site
762903002055	dimerization interface [polypeptide binding]; other site
762903002056	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
762903002057	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903002058	dimer interface [polypeptide binding]; other site
762903002059	phosphorylation site [posttranslational modification]
762903002060	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903002061	ATP binding site [chemical binding]; other site
762903002062	Mg2+ binding site [ion binding]; other site
762903002063	G-X-G motif; other site
762903002064	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
762903002065	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
762903002066	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
762903002067	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
762903002068	exopolysaccharide/PEP-CTERM locus tyrosine autokinase; Region: pepcterm_TyrKin; TIGR03018
762903002069	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
762903002070	transcriptional activator RfaH; Region: RfaH; TIGR01955
762903002071	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
762903002072	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
762903002073	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
762903002074	inhibitor-cofactor binding pocket; inhibition site
762903002075	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903002076	catalytic residue [active]
762903002077	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
762903002078	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
762903002079	active site
762903002080	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903002081	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
762903002082	putative ADP-binding pocket [chemical binding]; other site
762903002083	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
762903002084	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
762903002085	inhibitor-cofactor binding pocket; inhibition site
762903002086	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903002087	catalytic residue [active]
762903002088	Bacterial sugar transferase; Region: Bac_transf; pfam02397
762903002089	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
762903002090	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
762903002091	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
762903002092	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
762903002093	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903002094	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
762903002095	active site
762903002096	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903002097	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
762903002098	putative ADP-binding pocket [chemical binding]; other site
762903002099	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
762903002100	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
762903002101	active site
762903002102	dimer interface [polypeptide binding]; other site
762903002103	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
762903002104	Ligand Binding Site [chemical binding]; other site
762903002105	Molecular Tunnel; other site
762903002106	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903002107	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
762903002108	putative ADP-binding pocket [chemical binding]; other site
762903002109	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
762903002110	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
762903002111	active site
762903002112	dimer interface [polypeptide binding]; other site
762903002113	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
762903002114	Ligand Binding Site [chemical binding]; other site
762903002115	Molecular Tunnel; other site
762903002116	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
762903002117	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
762903002118	putative NAD(P) binding site [chemical binding]; other site
762903002119	active site
762903002120	putative substrate binding site [chemical binding]; other site
762903002121	Amb_all domain; Region: Amb_all; smart00656
762903002122	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
762903002123	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903002124	putative ADP-binding pocket [chemical binding]; other site
762903002125	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
762903002126	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
762903002127	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
762903002128	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
762903002129	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
762903002130	NAD(P) binding site [chemical binding]; other site
762903002131	homodimer interface [polypeptide binding]; other site
762903002132	substrate binding site [chemical binding]; other site
762903002133	active site
762903002134	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903002135	non-specific DNA binding site [nucleotide binding]; other site
762903002136	salt bridge; other site
762903002137	sequence-specific DNA binding site [nucleotide binding]; other site
762903002138	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903002139	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903002140	active site
762903002141	phosphorylation site [posttranslational modification]
762903002142	intermolecular recognition site; other site
762903002143	dimerization interface [polypeptide binding]; other site
762903002144	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903002145	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903002146	ligand binding site [chemical binding]; other site
762903002147	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
762903002148	non-specific DNA interactions [nucleotide binding]; other site
762903002149	DNA binding site [nucleotide binding]
762903002150	sequence specific DNA binding site [nucleotide binding]; other site
762903002151	putative cAMP binding site [chemical binding]; other site
762903002152	hypothetical protein; Provisional; Region: PRK07758
762903002153	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
762903002154	hydrophobic ligand binding site; other site
762903002155	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903002156	Two component regulator propeller; Region: Reg_prop; pfam07494
762903002157	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903002158	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903002159	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903002160	dimer interface [polypeptide binding]; other site
762903002161	phosphorylation site [posttranslational modification]
762903002162	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903002163	ATP binding site [chemical binding]; other site
762903002164	Mg2+ binding site [ion binding]; other site
762903002165	G-X-G motif; other site
762903002166	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903002167	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903002168	active site
762903002169	phosphorylation site [posttranslational modification]
762903002170	intermolecular recognition site; other site
762903002171	dimerization interface [polypeptide binding]; other site
762903002172	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
762903002173	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903002174	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903002175	beta-D-glucuronidase; Provisional; Region: PRK10150
762903002176	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903002177	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903002178	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
762903002179	Alginate lyase; Region: Alginate_lyase; pfam05426
762903002180	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903002181	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903002182	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903002183	active site
762903002184	metal binding site [ion binding]; metal-binding site
762903002185	Surface antigen; Region: Bac_surface_Ag; pfam01103
762903002186	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
762903002187	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903002188	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903002189	dimer interface [polypeptide binding]; other site
762903002190	phosphorylation site [posttranslational modification]
762903002191	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903002192	ATP binding site [chemical binding]; other site
762903002193	Mg2+ binding site [ion binding]; other site
762903002194	G-X-G motif; other site
762903002195	Response regulator receiver domain; Region: Response_reg; pfam00072
762903002196	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903002197	active site
762903002198	phosphorylation site [posttranslational modification]
762903002199	intermolecular recognition site; other site
762903002200	dimerization interface [polypeptide binding]; other site
762903002201	CcmE; Region: CcmE; cl00994
762903002202	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
762903002203	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
762903002204	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
762903002205	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
762903002206	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
762903002207	catalytic loop [active]
762903002208	iron binding site [ion binding]; other site
762903002209	Iron-sulphur cluster assembly; Region: Fe-S_assembly; pfam04384
762903002210	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
762903002211	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903002212	active site
762903002213	motif I; other site
762903002214	motif II; other site
762903002215	Cupin domain; Region: Cupin_2; pfam07883
762903002216	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903002217	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903002218	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903002219	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
762903002220	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
762903002221	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
762903002222	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
762903002223	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
762903002224	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
762903002225	putative hydrolase; Provisional; Region: PRK02113
762903002226	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
762903002227	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
762903002228	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
762903002229	active site
762903002230	DNA binding site [nucleotide binding]
762903002231	Int/Topo IB signature motif; other site
762903002232	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
762903002233	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
762903002234	catalytic residue [active]
762903002235	Domain of unknown function (DUF4248); Region: DUF4248; pfam14053
762903002236	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
762903002237	Phage associated DNA primase [General function prediction only]; Region: COG3378
762903002238	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903002239	non-specific DNA binding site [nucleotide binding]; other site
762903002240	salt bridge; other site
762903002241	sequence-specific DNA binding site [nucleotide binding]; other site
762903002242	CHC2 zinc finger; Region: zf-CHC2; cl17510
762903002243	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
762903002244	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
762903002245	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903002246	non-specific DNA binding site [nucleotide binding]; other site
762903002247	salt bridge; other site
762903002248	sequence-specific DNA binding site [nucleotide binding]; other site
762903002249	PEGA domain; Region: PEGA; pfam08308
762903002250	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
762903002251	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
762903002252	putative active site [active]
762903002253	putative metal binding site [ion binding]; other site
762903002254	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
762903002255	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
762903002256	Uncharacterized conserved protein [Function unknown]; Region: COG1739
762903002257	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
762903002258	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
762903002259	catalytic motif [active]
762903002260	Zn binding site [ion binding]; other site
762903002261	RibD C-terminal domain; Region: RibD_C; cl17279
762903002262	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
762903002263	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903002264	S-adenosylmethionine binding site [chemical binding]; other site
762903002265	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
762903002266	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
762903002267	active site
762903002268	Int/Topo IB signature motif; other site
762903002269	Dehydroquinase class II; Region: DHquinase_II; pfam01220
762903002270	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
762903002271	trimer interface [polypeptide binding]; other site
762903002272	active site
762903002273	dimer interface [polypeptide binding]; other site
762903002274	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
762903002275	putative hydrophobic ligand binding site [chemical binding]; other site
762903002276	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
762903002277	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903002278	Walker A/P-loop; other site
762903002279	ATP binding site [chemical binding]; other site
762903002280	ABC transporter signature motif; other site
762903002281	Walker B; other site
762903002282	D-loop; other site
762903002283	H-loop/switch region; other site
762903002284	ABC transporter; Region: ABC_tran_2; pfam12848
762903002285	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903002286	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
762903002287	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
762903002288	Walker A/P-loop; other site
762903002289	ATP binding site [chemical binding]; other site
762903002290	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; pfam06470
762903002291	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
762903002292	dimer interface [polypeptide binding]; other site
762903002293	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
762903002294	Q-loop/lid; other site
762903002295	ABC transporter signature motif; other site
762903002296	Walker B; other site
762903002297	D-loop; other site
762903002298	H-loop/switch region; other site
762903002299	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903002300	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
762903002301	Domain of unknown function (DUF2383); Region: DUF2383; cl17556
762903002302	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903002303	S-adenosylmethionine binding site [chemical binding]; other site
762903002304	Aspartokinases [Amino acid transport and metabolism]; Region: LysC; COG0527
762903002305	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
762903002306	nucleotide binding site [chemical binding]; other site
762903002307	substrate binding site [chemical binding]; other site
762903002308	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
762903002309	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
762903002310	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
762903002311	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
762903002312	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903002313	Coenzyme A binding pocket [chemical binding]; other site
762903002314	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
762903002315	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
762903002316	catalytic residue [active]
762903002317	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
762903002318	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
762903002319	MutS domain III; Region: MutS_III; pfam05192
762903002320	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903002321	Walker A/P-loop; other site
762903002322	ATP binding site [chemical binding]; other site
762903002323	Q-loop/lid; other site
762903002324	ABC transporter signature motif; other site
762903002325	Walker B; other site
762903002326	D-loop; other site
762903002327	H-loop/switch region; other site
762903002328	Smr domain; Region: Smr; pfam01713
762903002329	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
762903002330	Flavoprotein; Region: Flavoprotein; pfam02441
762903002331	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
762903002332	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
762903002333	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903002334	FeS/SAM binding site; other site
762903002335	GtrA-like protein; Region: GtrA; pfam04138
762903002336	Predicted membrane protein [Function unknown]; Region: COG2246
762903002337	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
762903002338	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
762903002339	active site
762903002340	dimerization interface [polypeptide binding]; other site
762903002341	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
762903002342	putative active site [active]
762903002343	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903002344	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903002345	Predicted membrane protein [Function unknown]; Region: COG3650
762903002346	methylglyoxal synthase; Validated; Region: mgsA; PRK05234
762903002347	substrate binding site [chemical binding]; other site
762903002348	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
762903002349	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
762903002350	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
762903002351	active site
762903002352	catalytic site [active]
762903002353	substrate binding site [chemical binding]; other site
762903002354	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
762903002355	MAEBL; Provisional; Region: PTZ00121
762903002356	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
762903002357	amidase catalytic site [active]
762903002358	Zn binding residues [ion binding]; other site
762903002359	substrate binding site [chemical binding]; other site
762903002360	Holin family; Region: Phage_holin_4; cl01989
762903002361	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
762903002362	Homeodomain-like domain; Region: HTH_23; pfam13384
762903002363	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
762903002364	Protein of unknown function (DUF935); Region: DUF935; pfam06074
762903002365	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
762903002366	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
762903002367	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
762903002368	catalytic motif [active]
762903002369	Catalytic residue [active]
762903002370	SEC-C motif; Region: SEC-C; pfam02810
762903002371	Src homology 2 (SH2) domain; Region: SH2; cl15255
762903002372	phosphotyrosine binding pocket [polypeptide binding]; other site
762903002373	Telomeric Repeat binding Factor or TTAGGG Repeat binding Factor, central (dimerization) domain Homology; TRFH. Telomeres are protein/DNA complexes that make up the physical ends of eukaryotic linear chromosomes and are essential for chromosome stability; Region: TRFH; cl02779
762903002374	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
762903002375	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
762903002376	ASC-1 homology domain, ASC-1-like subfamily. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain...; Region: ASCH_ASC-1_like; cd06554
762903002377	Domain of unknown function (DUF4406); Region: DUF4406; pfam14359
762903002378	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
762903002379	AAA domain; Region: AAA_25; pfam13481
762903002380	AAA domain; Region: AAA_22; pfam13401
762903002381	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
762903002382	ATP binding site [chemical binding]; other site
762903002383	Walker A motif; other site
762903002384	Walker B motif; other site
762903002385	Helix-turn-helix domain; Region: HTH_19; pfam12844
762903002386	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
762903002387	Predicted transcriptional regulator [Transcription]; Region: COG2932
762903002388	Catalytic site [active]
762903002389	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
762903002390	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
762903002391	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903002392	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903002393	dimer interface [polypeptide binding]; other site
762903002394	phosphorylation site [posttranslational modification]
762903002395	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903002396	ATP binding site [chemical binding]; other site
762903002397	Mg2+ binding site [ion binding]; other site
762903002398	G-X-G motif; other site
762903002399	RecX family; Region: RecX; pfam02631
762903002400	putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional; Region: PRK11930
762903002401	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
762903002402	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
762903002403	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
762903002404	active site
762903002405	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
762903002406	dimer interface [polypeptide binding]; other site
762903002407	substrate binding site [chemical binding]; other site
762903002408	catalytic residues [active]
762903002409	Protein of unknown function (DUF502); Region: DUF502; cl01107
762903002410	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
762903002411	menaquinone biosynthesis protein, SCO4550 family; Region: mena_SCO4550; TIGR03699
762903002412	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903002413	FeS/SAM binding site; other site
762903002414	Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149
762903002415	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
762903002416	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
762903002417	THF binding site; other site
762903002418	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
762903002419	substrate binding site [chemical binding]; other site
762903002420	THF binding site; other site
762903002421	zinc-binding site [ion binding]; other site
762903002422	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903002423	active site
762903002424	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
762903002425	Domain of unknown function DUF87; Region: DUF87; pfam01935
762903002426	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
762903002427	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903002428	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
762903002429	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
762903002430	oligomer interface [polypeptide binding]; other site
762903002431	active site
762903002432	metal binding site [ion binding]; metal-binding site
762903002433	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
762903002434	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903002435	Coenzyme A binding pocket [chemical binding]; other site
762903002436	Domain of unknown function (DUF386); Region: DUF386; cl01047
762903002437	Domain of unknown function (DUF386); Region: DUF386; cl01047
762903002438	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
762903002439	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
762903002440	substrate binding site [chemical binding]; other site
762903002441	hexamer interface [polypeptide binding]; other site
762903002442	metal binding site [ion binding]; metal-binding site
762903002443	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903002444	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903002445	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903002446	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
762903002447	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
762903002448	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
762903002449	catalytic residue [active]
762903002450	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
762903002451	Phosphoglycerate dehydrogenase (PGDH) NAD-binding and catalytic domains; Region: PGDH_2; cd05303
762903002452	putative ligand binding site [chemical binding]; other site
762903002453	NAD binding site [chemical binding]; other site
762903002454	dimerization interface [polypeptide binding]; other site
762903002455	catalytic site [active]
762903002456	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
762903002457	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
762903002458	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
762903002459	acyl-activating enzyme (AAE) consensus motif; other site
762903002460	acyl-activating enzyme (AAE) consensus motif; other site
762903002461	putative AMP binding site [chemical binding]; other site
762903002462	putative active site [active]
762903002463	putative CoA binding site [chemical binding]; other site
762903002464	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
762903002465	Predicted metalloprotease [General function prediction only]; Region: COG2321
762903002466	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
762903002467	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
762903002468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903002469	putative substrate translocation pore; other site
762903002470	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903002471	glucosamine-6-phosphate deaminase-like protein; Validated; Region: PRK02122
762903002472	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
762903002473	active site
762903002474	trimer interface [polypeptide binding]; other site
762903002475	allosteric site; other site
762903002476	active site lid [active]
762903002477	hexamer (dimer of trimers) interface [polypeptide binding]; other site
762903002478	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
762903002479	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
762903002480	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
762903002481	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
762903002482	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
762903002483	Broad specificity phosphatase PhoE and related phosphatases [General function prediction only]; Region: phoE; COG0406
762903002484	catalytic core [active]
762903002485	Peptidase S46; Region: Peptidase_S46; pfam10459
762903002486	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
762903002487	Integrase core domain; Region: rve; pfam00665
762903002488	Integrase core domain; Region: rve_3; pfam13683
762903002489	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
762903002490	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
762903002491	GAF domain; Region: GAF_2; pfam13185
762903002492	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
762903002493	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
762903002494	Histone deacetylase class IV also known as histone deacetylase 11; Region: HDAC_classIV; cd09993
762903002495	putative active site [active]
762903002496	Zn binding site [ion binding]; other site
762903002497	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
762903002498	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
762903002499	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
762903002500	Substrate binding site; other site
762903002501	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
762903002502	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
762903002503	putative active site [active]
762903002504	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
762903002505	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
762903002506	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903002507	ATP binding site [chemical binding]; other site
762903002508	putative Mg++ binding site [ion binding]; other site
762903002509	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903002510	nucleotide binding region [chemical binding]; other site
762903002511	ATP-binding site [chemical binding]; other site
762903002512	RQC domain; Region: RQC; pfam09382
762903002513	HRDC domain; Region: HRDC; pfam00570
762903002514	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
762903002515	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903002516	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
762903002517	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
762903002518	colanic acid exporter; Provisional; Region: PRK10459
762903002519	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
762903002520	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: GT1_like_1; cd04950
762903002521	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903002522	putative homodimer interface [polypeptide binding]; other site
762903002523	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903002524	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
762903002525	active site
762903002526	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
762903002527	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
762903002528	Ligand binding site; other site
762903002529	metal-binding site
762903002530	O-Antigen ligase; Region: Wzy_C; pfam04932
762903002531	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903002532	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
762903002533	DXD motif; other site
762903002534	chain length determinant protein EpsF; Region: EpsF; TIGR03017
762903002535	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
762903002536	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
762903002537	Outer membrane efflux protein; Region: OEP; pfam02321
762903002538	legume lectins; Region: lectin_L-type; cl14058
762903002539	homotetramer interaction site [polypeptide binding]; other site
762903002540	carbohydrate binding site [chemical binding]; other site
762903002541	metal binding site [ion binding]; metal-binding site
762903002542	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903002543	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903002544	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903002545	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903002546	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903002547	ligand binding site [chemical binding]; other site
762903002548	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
762903002549	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
762903002550	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903002551	putative substrate translocation pore; other site
762903002552	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903002553	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
762903002554	Probable Catalytic site; other site
762903002555	metal-binding site
762903002556	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
762903002557	putative acyl-acceptor binding pocket; other site
762903002558	WbqC-like protein family; Region: WbqC; pfam08889
762903002559	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
762903002560	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
762903002561	oligomer interface [polypeptide binding]; other site
762903002562	metal binding site [ion binding]; metal-binding site
762903002563	metal binding site [ion binding]; metal-binding site
762903002564	Cl binding site [ion binding]; other site
762903002565	aspartate ring; other site
762903002566	basic sphincter; other site
762903002567	putative hydrophobic gate; other site
762903002568	periplasmic entrance; other site
762903002569	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
762903002570	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
762903002571	catalytic residues [active]
762903002572	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
762903002573	TIGR01666 family membrane protein; Region: YCCS
762903002574	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
762903002575	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
762903002576	Trehalose utilisation; Region: ThuA; pfam06283
762903002577	helicase 45; Provisional; Region: PTZ00424
762903002578	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
762903002579	ATP binding site [chemical binding]; other site
762903002580	Mg++ binding site [ion binding]; other site
762903002581	motif III; other site
762903002582	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903002583	nucleotide binding region [chemical binding]; other site
762903002584	ATP-binding site [chemical binding]; other site
762903002585	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903002586	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903002587	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
762903002588	DNA binding residues [nucleotide binding]
762903002589	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903002590	FecR protein; Region: FecR; pfam04773
762903002591	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903002592	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903002593	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903002594	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903002595	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903002596	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903002597	SusD family; Region: SusD; pfam07980
762903002598	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
762903002599	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
762903002600	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
762903002601	TrkA-C domain; Region: TrkA_C; pfam02080
762903002602	TrkA-C domain; Region: TrkA_C; pfam02080
762903002603	ATP-dependent DNA ligase; Reviewed; Region: ligD; PRK05972
762903002604	DNA polymerase Ligase (LigD); Region: LigD_N; cl11819
762903002605	Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906
762903002606	active site
762903002607	DNA binding site [nucleotide binding]
762903002608	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigD is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigD; cd07971
762903002609	DNA binding site [nucleotide binding]
762903002610	LigD_Pol_like_2: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD, subgroup 2. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required...; Region: LigD_Pol_like_2; cd04865
762903002611	nucleotide binding site [chemical binding]; other site
762903002612	Ku protein, prokaryotic; Region: Ku_bact; TIGR02772
762903002613	Ku-core domain; includes the central DNA-binding beta-barrels, polypeptide rings, and the C-terminal arm of Ku proteins. The Ku protein consists of two tightly associated homologous subunits, Ku70 and Ku80, and was originally identified as an autoantigen...; Region: KU; cl02666
762903002614	DNA binding site [nucleotide binding]
762903002615	heterodimer interface [polypeptide binding]; other site
762903002616	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
762903002617	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903002618	binding surface
762903002619	TPR motif; other site
762903002620	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903002621	binding surface
762903002622	Tetratricopeptide repeat; Region: TPR_16; pfam13432
762903002623	TPR motif; other site
762903002624	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903002625	TPR motif; other site
762903002626	binding surface
762903002627	DNA gyrase subunit A; Validated; Region: PRK05560
762903002628	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
762903002629	CAP-like domain; other site
762903002630	active site
762903002631	primary dimer interface [polypeptide binding]; other site
762903002632	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
762903002633	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
762903002634	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
762903002635	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
762903002636	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
762903002637	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
762903002638	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903002639	FeS/SAM binding site; other site
762903002640	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903002641	binding surface
762903002642	Tetratricopeptide repeat; Region: TPR_16; pfam13432
762903002643	TPR motif; other site
762903002644	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
762903002645	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
762903002646	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
762903002647	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903002648	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903002649	ligand binding site [chemical binding]; other site
762903002650	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
762903002651	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
762903002652	RNase E interface [polypeptide binding]; other site
762903002653	trimer interface [polypeptide binding]; other site
762903002654	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
762903002655	RNase E interface [polypeptide binding]; other site
762903002656	trimer interface [polypeptide binding]; other site
762903002657	active site
762903002658	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
762903002659	putative nucleic acid binding region [nucleotide binding]; other site
762903002660	G-X-X-G motif; other site
762903002661	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
762903002662	RNA binding site [nucleotide binding]; other site
762903002663	domain interface; other site
762903002664	CTP synthetase; Validated; Region: pyrG; PRK05380
762903002665	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
762903002666	Catalytic site [active]
762903002667	active site
762903002668	UTP binding site [chemical binding]; other site
762903002669	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
762903002670	active site
762903002671	putative oxyanion hole; other site
762903002672	catalytic triad [active]
762903002673	membrane protein insertase; Provisional; Region: PRK01318
762903002674	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
762903002675	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903002676	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903002677	active site
762903002678	phosphorylation site [posttranslational modification]
762903002679	intermolecular recognition site; other site
762903002680	dimerization interface [polypeptide binding]; other site
762903002681	Bacterial sugar transferase; Region: Bac_transf; pfam02397
762903002682	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
762903002683	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
762903002684	active site
762903002685	catalytic site [active]
762903002686	substrate binding site [chemical binding]; other site
762903002687	Predicted signal-transduction protein containing cAMP-binding and CBS domains [Signal transduction mechanisms]; Region: COG2905
762903002688	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
762903002689	ligand binding site [chemical binding]; other site
762903002690	flexible hinge region; other site
762903002691	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with either the CAP_ED (cAMP receptor protein effector domain) family of transcription factors and the DUF294 domain or the PB1 (Phox and Bem1p) domain; Region: CBS_pair_CAP-ED_DUF294_PBI_assoc2; cd04800
762903002692	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
762903002693	metal binding triad; other site
762903002694	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
762903002695	16S/18S rRNA binding site [nucleotide binding]; other site
762903002696	S13e-L30e interaction site [polypeptide binding]; other site
762903002697	25S rRNA binding site [nucleotide binding]; other site
762903002698	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
762903002699	active site
762903002700	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
762903002701	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
762903002702	ATP-grasp domain; Region: ATP-grasp_4; cl17255
762903002703	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
762903002704	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
762903002705	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
762903002706	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
762903002707	active site residue [active]
762903002708	YceG-like family; Region: YceG; pfam02618
762903002709	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
762903002710	dimerization interface [polypeptide binding]; other site
762903002711	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
762903002712	active site
762903002713	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
762903002714	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
762903002715	beta-galactosidase; Region: BGL; TIGR03356
762903002716	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
762903002717	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
762903002718	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903002719	catalytic residues [active]
762903002720	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903002721	Coenzyme A binding pocket [chemical binding]; other site
762903002722	Predicted amidohydrolase [General function prediction only]; Region: COG0388
762903002723	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
762903002724	putative active site [active]
762903002725	catalytic triad [active]
762903002726	putative dimer interface [polypeptide binding]; other site
762903002727	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_6; cd01844
762903002728	active site
762903002729	catalytic triad [active]
762903002730	oxyanion hole [active]
762903002731	Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain; Region: NAGLU_N; pfam12971
762903002732	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain; Region: NAGLU; pfam05089
762903002733	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; Region: NAGLU_C; pfam12972
762903002734	Uncharacterized conserved protein [Function unknown]; Region: COG1262
762903002735	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
762903002736	BNR repeat-like domain; Region: BNR_2; pfam13088
762903002737	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
762903002738	Asp-box motif; other site
762903002739	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903002740	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903002741	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903002742	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903002743	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903002744	SusD family; Region: SusD; pfam07980
762903002745	Secretin and TonB N terminus short domain; Region: STN; pfam07660
762903002746	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903002747	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903002748	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903002749	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903002750	FecR protein; Region: FecR; pfam04773
762903002751	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
762903002752	BNR repeat-like domain; Region: BNR_2; pfam13088
762903002753	Asp-box motif; other site
762903002754	catalytic site [active]
762903002755	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
762903002756	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
762903002757	active site
762903002758	active site
762903002759	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903002760	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903002761	DNA binding residues [nucleotide binding]
762903002762	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
762903002763	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
762903002764	active site
762903002765	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_9; cd07245
762903002766	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903002767	dimer interface [polypeptide binding]; other site
762903002768	putative metal binding site [ion binding]; other site
762903002769	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
762903002770	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
762903002771	DNA photolyase; Region: DNA_photolyase; pfam00875
762903002772	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
762903002773	Transposase; Region: DEDD_Tnp_IS110; pfam01548
762903002774	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
762903002775	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
762903002776	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
762903002777	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
762903002778	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
762903002779	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
762903002780	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
762903002781	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
762903002782	Cysteine-rich domain; Region: CCG; pfam02754
762903002783	Cysteine-rich domain; Region: CCG; pfam02754
762903002784	Cupin domain; Region: Cupin_2; pfam07883
762903002785	transcriptional activator RhaS; Provisional; Region: PRK13503
762903002786	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903002787	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
762903002788	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
762903002789	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
762903002790	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
762903002791	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
762903002792	active site
762903002793	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
762903002794	methionine aminotransferase; Validated; Region: PRK09082
762903002795	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
762903002796	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903002797	homodimer interface [polypeptide binding]; other site
762903002798	catalytic residue [active]
762903002799	C-N hydrolase family amidase; Provisional; Region: PRK10438
762903002800	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
762903002801	putative active site [active]
762903002802	catalytic triad [active]
762903002803	dimer interface [polypeptide binding]; other site
762903002804	multimer interface [polypeptide binding]; other site
762903002805	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
762903002806	active site
762903002807	DNA polymerase IV; Validated; Region: PRK02406
762903002808	DNA binding site [nucleotide binding]
762903002809	Protein of unknown function (DUF763); Region: DUF763; pfam05559
762903002810	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
762903002811	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
762903002812	FtsX-like permease family; Region: FtsX; pfam02687
762903002813	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
762903002814	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
762903002815	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
762903002816	substrate binding site; other site
762903002817	dimer interface; other site
762903002818	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
762903002819	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
762903002820	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
762903002821	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
762903002822	ribonuclease Z; Region: RNase_Z; TIGR02651
762903002823	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
762903002824	anti sigma factor interaction site; other site
762903002825	regulatory phosphorylation site [posttranslational modification]; other site
762903002826	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
762903002827	ATP binding site [chemical binding]; other site
762903002828	active site
762903002829	substrate binding site [chemical binding]; other site
762903002830	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
762903002831	PhoH-like protein; Region: PhoH; pfam02562
762903002832	S-adenosyl-l-methionine hydroxide adenosyltransferase; Region: SAM_adeno_trans; pfam01887
762903002833	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
762903002834	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
762903002835	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
762903002836	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
762903002837	active site
762903002838	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
762903002839	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
762903002840	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
762903002841	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
762903002842	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
762903002843	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903002844	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903002845	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903002846	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
762903002847	MutS domain I; Region: MutS_I; pfam01624
762903002848	MutS domain II; Region: MutS_II; pfam05188
762903002849	MutS domain III; Region: MutS_III; pfam05192
762903002850	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
762903002851	Walker A/P-loop; other site
762903002852	ATP binding site [chemical binding]; other site
762903002853	Q-loop/lid; other site
762903002854	ABC transporter signature motif; other site
762903002855	Walker B; other site
762903002856	D-loop; other site
762903002857	H-loop/switch region; other site
762903002858	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
762903002859	Transposase; Region: DEDD_Tnp_IS110; pfam01548
762903002860	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
762903002861	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
762903002862	classical (c) SDRs; Region: SDR_c; cd05233
762903002863	NAD(P) binding site [chemical binding]; other site
762903002864	active site
762903002865	DinB superfamily; Region: DinB_2; pfam12867
762903002866	DinB family; Region: DinB; cl17821
762903002867	Dienelactone hydrolase family; Region: DLH; pfam01738
762903002868	Menaquinone biosynthesis; Region: VitK2_biosynth; pfam02621
762903002869	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
762903002870	catalytic core [active]
762903002871	putative menaquinone biosynthesis protein, SCO4494 family; Region: mena_SCO4494; TIGR03700
762903002872	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903002873	FeS/SAM binding site; other site
762903002874	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
762903002875	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
762903002876	homodimer interface [polypeptide binding]; other site
762903002877	substrate-cofactor binding pocket; other site
762903002878	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903002879	catalytic residue [active]
762903002880	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
762903002881	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
762903002882	homodimer interface [polypeptide binding]; other site
762903002883	substrate-cofactor binding pocket; other site
762903002884	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903002885	catalytic residue [active]
762903002886	homoserine dehydrogenase; Provisional; Region: PRK06270
762903002887	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
762903002888	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
762903002889	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
762903002890	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903002891	putative substrate translocation pore; other site
762903002892	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
762903002893	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
762903002894	PAS domain; Region: PAS_9; pfam13426
762903002895	PAS domain; Region: PAS; smart00091
762903002896	nitrogen fixation negative regulator NifL; Region: nifL_nitrog; TIGR02938
762903002897	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903002898	putative active site [active]
762903002899	heme pocket [chemical binding]; other site
762903002900	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903002901	dimer interface [polypeptide binding]; other site
762903002902	phosphorylation site [posttranslational modification]
762903002903	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903002904	ATP binding site [chemical binding]; other site
762903002905	Mg2+ binding site [ion binding]; other site
762903002906	G-X-G motif; other site
762903002907	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903002908	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903002909	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
762903002910	hydroperoxidase II; Provisional; Region: katE; PRK11249
762903002911	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
762903002912	tetramer interface [polypeptide binding]; other site
762903002913	heme binding pocket [chemical binding]; other site
762903002914	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
762903002915	domain interactions; other site
762903002916	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
762903002917	dinuclear metal binding motif [ion binding]; other site
762903002918	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
762903002919	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
762903002920	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
762903002921	iron-sulfur cluster [ion binding]; other site
762903002922	[2Fe-2S] cluster binding site [ion binding]; other site
762903002923	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
762903002924	catalytic nucleophile [active]
762903002925	putative phosphoketolase; Provisional; Region: PRK05261
762903002926	Thiamine pyrophosphate (TPP) family, Phosphoketolase (PK) subfamily, TPP-binding module; PK catalyzes the conversion of D-xylulose 5-phosphate and phosphate to acetyl phosphate, D-glyceraldehyde-3-phosphate and H2O. This enzyme requires divalent...; Region: TPP_PK; cd02011
762903002927	TPP-binding site; other site
762903002928	XFP C-terminal domain; Region: XFP_C; pfam09363
762903002929	Acetokinase family; Region: Acetate_kinase; cl17229
762903002930	propionate/acetate kinase; Provisional; Region: PRK12379
762903002931	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
762903002932	classical (c) SDRs; Region: SDR_c; cd05233
762903002933	NAD(P) binding site [chemical binding]; other site
762903002934	active site
762903002935	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
762903002936	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH2; cd08286
762903002937	catalytic Zn binding site [ion binding]; other site
762903002938	structural Zn binding site [ion binding]; other site
762903002939	NAD(P) binding site [chemical binding]; other site
762903002940	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
762903002941	dinuclear metal binding motif [ion binding]; other site
762903002942	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
762903002943	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
762903002944	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
762903002945	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
762903002946	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
762903002947	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
762903002948	Walker A/P-loop; other site
762903002949	ATP binding site [chemical binding]; other site
762903002950	Q-loop/lid; other site
762903002951	ABC transporter signature motif; other site
762903002952	Walker B; other site
762903002953	D-loop; other site
762903002954	H-loop/switch region; other site
762903002955	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
762903002956	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
762903002957	Walker A/P-loop; other site
762903002958	ATP binding site [chemical binding]; other site
762903002959	Q-loop/lid; other site
762903002960	ABC transporter signature motif; other site
762903002961	Walker B; other site
762903002962	D-loop; other site
762903002963	H-loop/switch region; other site
762903002964	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903002965	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903002966	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903002967	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
762903002968	Uncharacterized lipoprotein NlpE involved in copper resistance [Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism]; Region: CutF; COG3015
762903002969	NlpE N-terminal domain; Region: NlpE; pfam04170
762903002970	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
762903002971	active site
762903002972	catalytic site [active]
762903002973	substrate binding site [chemical binding]; other site
762903002974	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
762903002975	GIY-YIG motif/motif A; other site
762903002976	active site
762903002977	catalytic site [active]
762903002978	putative DNA binding site [nucleotide binding]; other site
762903002979	metal binding site [ion binding]; metal-binding site
762903002980	HEAT repeats; Region: HEAT_2; pfam13646
762903002981	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
762903002982	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903002983	Major Facilitator Superfamily; Region: MFS_1; pfam07690
762903002984	putative substrate translocation pore; other site
762903002985	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
762903002986	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
762903002987	classical (c) SDRs; Region: SDR_c; cd05233
762903002988	NAD(P) binding site [chemical binding]; other site
762903002989	active site
762903002990	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903002991	putative substrate translocation pore; other site
762903002992	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
762903002993	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903002994	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
762903002995	Cupin domain; Region: Cupin_2; pfam07883
762903002996	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
762903002997	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
762903002998	Transcriptional regulators [Transcription]; Region: FadR; COG2186
762903002999	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
762903003000	DNA-binding site [nucleotide binding]; DNA binding site
762903003001	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
762903003002	Polysaccharide lyase; Region: Polysacc_lyase; pfam14099
762903003003	ATP cone domain; Region: ATP-cone; pfam03477
762903003004	Restriction endonuclease; Region: Mrr_cat; pfam04471
762903003005	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
762903003006	?-D-glucose-1-phosphatase; Provisional; Region: PRK09456
762903003007	S4 domain; Region: S4_2; pfam13275
762903003008	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
762903003009	active site
762903003010	dimer interface [polypeptide binding]; other site
762903003011	metal binding site [ion binding]; metal-binding site
762903003012	Transglycosylase; Region: Transgly; pfam00912
762903003013	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
762903003014	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
762903003015	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
762903003016	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
762903003017	Surface antigen; Region: Bac_surface_Ag; pfam01103
762903003018	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
762903003019	GIY-YIG motif/motif A; other site
762903003020	putative active site [active]
762903003021	putative metal binding site [ion binding]; other site
762903003022	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
762903003023	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903003024	non-specific DNA binding site [nucleotide binding]; other site
762903003025	salt bridge; other site
762903003026	sequence-specific DNA binding site [nucleotide binding]; other site
762903003027	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
762903003028	Catalytic site [active]
762903003029	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
762903003030	active site
762903003031	catalytic residues [active]
762903003032	DNA polymerase III subunit epsilon; Validated; Region: PRK06309
762903003033	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
762903003034	active site
762903003035	catalytic site [active]
762903003036	substrate binding site [chemical binding]; other site
762903003037	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
762903003038	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903003039	putative catalytic residue [active]
762903003040	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
762903003041	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903003042	catalytic residues [active]
762903003043	NlpC/P60 family; Region: NLPC_P60; pfam00877
762903003044	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
762903003045	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
762903003046	active site
762903003047	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
762903003048	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
762903003049	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903003050	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903003051	S-adenosylmethionine binding site [chemical binding]; other site
762903003052	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903003053	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
762903003054	putative active site [active]
762903003055	putative metal binding site [ion binding]; other site
762903003056	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
762903003057	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
762903003058	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
762903003059	phosphoribosylaminoimidazole synthetase; Region: purM; TIGR00878
762903003060	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
762903003061	dimerization interface [polypeptide binding]; other site
762903003062	ATP binding site [chemical binding]; other site
762903003063	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
762903003064	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
762903003065	putative luciferase-like monooxygenase, FMN-dependent, CE1758 family; Region: LLM_CE1758_fam; TIGR04036
762903003066	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
762903003067	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
762903003068	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903003069	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
762903003070	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903003071	Protein of unknown function (DUF2721); Region: DUF2721; pfam11026
762903003072	transcript cleavage factor/unknown domain fusion protein; Validated; Region: PRK06330
762903003073	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
762903003074	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
762903003075	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
762903003076	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
762903003077	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
762903003078	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903003079	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
762903003080	DNA binding residues [nucleotide binding]
762903003081	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
762903003082	hypothetical protein; Provisional; Region: PRK08201
762903003083	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
762903003084	metal binding site [ion binding]; metal-binding site
762903003085	putative dimer interface [polypeptide binding]; other site
762903003086	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903003087	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903003088	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
762903003089	Part of AAA domain; Region: AAA_19; pfam13245
762903003090	Family description; Region: UvrD_C_2; pfam13538
762903003091	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
762903003092	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
762903003093	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
762903003094	hinge; other site
762903003095	active site
762903003096	ribonuclease R; Region: RNase_R; TIGR02063
762903003097	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
762903003098	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
762903003099	RNB domain; Region: RNB; pfam00773
762903003100	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
762903003101	RNA binding site [nucleotide binding]; other site
762903003102	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
762903003103	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
762903003104	substrate binding pocket [chemical binding]; other site
762903003105	chain length determination region; other site
762903003106	substrate-Mg2+ binding site; other site
762903003107	catalytic residues [active]
762903003108	aspartate-rich region 1; other site
762903003109	active site lid residues [active]
762903003110	aspartate-rich region 2; other site
762903003111	HopJ type III effector protein; Region: HopJ; pfam08888
762903003112	2'-5' RNA ligase [Translation, ribosomal structure and biogenesis]; Region: LigT; COG1514
762903003113	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
762903003114	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
762903003115	N-terminal plug; other site
762903003116	ligand-binding site [chemical binding]; other site
762903003117	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
762903003118	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
762903003119	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
762903003120	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
762903003121	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
762903003122	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903003123	Walker A/P-loop; other site
762903003124	ATP binding site [chemical binding]; other site
762903003125	Q-loop/lid; other site
762903003126	ABC transporter signature motif; other site
762903003127	Walker B; other site
762903003128	D-loop; other site
762903003129	H-loop/switch region; other site
762903003130	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
762903003131	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
762903003132	dimer interface [polypeptide binding]; other site
762903003133	putative radical transfer pathway; other site
762903003134	diiron center [ion binding]; other site
762903003135	tyrosyl radical; other site
762903003136	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
762903003137	Class I ribonucleotide reductase; Region: RNR_I; cd01679
762903003138	active site
762903003139	dimer interface [polypeptide binding]; other site
762903003140	catalytic residues [active]
762903003141	effector binding site; other site
762903003142	R2 peptide binding site; other site
762903003143	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
762903003144	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
762903003145	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
762903003146	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
762903003147	putative active site [active]
762903003148	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
762903003149	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
762903003150	putative ribose interaction site [chemical binding]; other site
762903003151	putative ADP binding site [chemical binding]; other site
762903003152	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
762903003153	active site
762903003154	nucleotide binding site [chemical binding]; other site
762903003155	HIGH motif; other site
762903003156	KMSKS motif; other site
762903003157	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
762903003158	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903003159	active site
762903003160	motif I; other site
762903003161	motif II; other site
762903003162	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
762903003163	D-inositol-3-phosphate glycosyltransferase; Region: mycothiol_MshA; TIGR03449
762903003164	putative ADP-binding pocket [chemical binding]; other site
762903003165	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
762903003166	dimer interface [polypeptide binding]; other site
762903003167	active site
762903003168	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
762903003169	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903003170	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
762903003171	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
762903003172	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903003173	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903003174	ABC transporter; Region: ABC_tran_2; pfam12848
762903003175	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903003176	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
762903003177	GIY-YIG motif/motif A; other site
762903003178	putative active site [active]
762903003179	putative metal binding site [ion binding]; other site
762903003180	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
762903003181	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
762903003182	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
762903003183	ligand binding site [chemical binding]; other site
762903003184	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903003185	non-specific DNA binding site [nucleotide binding]; other site
762903003186	salt bridge; other site
762903003187	sequence-specific DNA binding site [nucleotide binding]; other site
762903003188	Bacteriophage abortive infection AbiH; Region: AbiH; pfam14253
762903003189	Bacteriophage abortive infection AbiH; Region: AbiH; pfam14253
762903003190	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
762903003191	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
762903003192	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
762903003193	ATP binding site [chemical binding]; other site
762903003194	putative Mg++ binding site [ion binding]; other site
762903003195	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
762903003196	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
762903003197	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
762903003198	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
762903003199	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
762903003200	HsdM N-terminal domain; Region: HsdM_N; pfam12161
762903003201	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
762903003202	Methyltransferase domain; Region: Methyltransf_26; pfam13659
762903003203	TIGR02594 family protein; Region: TIGR02594
762903003204	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903003205	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903003206	ligand binding site [chemical binding]; other site
762903003207	flexible hinge region; other site
762903003208	Membrane bound O-acyl transferase family; Region: MBOAT_2; pfam13813
762903003209	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903003210	TIGR01777 family protein; Region: yfcH
762903003211	NAD(P) binding site [chemical binding]; other site
762903003212	active site
762903003213	Protein of unknown function, DUF393; Region: DUF393; cl01136
762903003214	Predicted transcriptional regulators [Transcription]; Region: COG1510
762903003215	Sugar-specific transcriptional regulator TrmB; Region: TrmB; cl17775
762903003216	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903003217	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903003218	dimer interface [polypeptide binding]; other site
762903003219	phosphorylation site [posttranslational modification]
762903003220	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903003221	ATP binding site [chemical binding]; other site
762903003222	Mg2+ binding site [ion binding]; other site
762903003223	G-X-G motif; other site
762903003224	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
762903003225	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
762903003226	dimerization interface [polypeptide binding]; other site
762903003227	metal binding site [ion binding]; metal-binding site
762903003228	Major Facilitator Superfamily; Region: MFS_1; pfam07690
762903003229	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903003230	putative substrate translocation pore; other site
762903003231	Predicted transcriptional regulators [Transcription]; Region: COG1733
762903003232	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
762903003233	DoxX-like family; Region: DoxX_2; pfam13564
762903003234	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
762903003235	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
762903003236	catalytic residues [active]
762903003237	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cd00296
762903003238	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
762903003239	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
762903003240	dimerization interface [polypeptide binding]; other site
762903003241	ATP binding site [chemical binding]; other site
762903003242	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
762903003243	dimerization interface [polypeptide binding]; other site
762903003244	ATP binding site [chemical binding]; other site
762903003245	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
762903003246	putative active site [active]
762903003247	catalytic triad [active]
762903003248	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
762903003249	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
762903003250	ATP binding site [chemical binding]; other site
762903003251	Mg++ binding site [ion binding]; other site
762903003252	motif III; other site
762903003253	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903003254	nucleotide binding region [chemical binding]; other site
762903003255	ATP-binding site [chemical binding]; other site
762903003256	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
762903003257	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
762903003258	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
762903003259	catalytic residues [active]
762903003260	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
762903003261	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
762903003262	active site
762903003263	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
762903003264	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
762903003265	Outer membrane efflux protein; Region: OEP; pfam02321
762903003266	Outer membrane efflux protein; Region: OEP; pfam02321
762903003267	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
762903003268	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903003269	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903003270	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
762903003271	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903003272	putative substrate translocation pore; other site
762903003273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903003274	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
762903003275	dimer interface [polypeptide binding]; other site
762903003276	ligand binding site [chemical binding]; other site
762903003277	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
762903003278	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
762903003279	substrate binding pocket [chemical binding]; other site
762903003280	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903003281	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
762903003282	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
762903003283	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903003284	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903003285	active site
762903003286	metal binding site [ion binding]; metal-binding site
762903003287	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
762903003288	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
762903003289	Competence protein; Region: Competence; pfam03772
762903003290	Sulfatase; Region: Sulfatase; pfam00884
762903003291	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
762903003292	active site
762903003293	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903003294	This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides; Region: GT1_ecORF704_like; cd03822
762903003295	Uncharacterized conserved protein [Function unknown]; Region: COG4544
762903003296	DNA Polymerase Y-family; Region: PolY_like; cd03468
762903003297	active site
762903003298	DNA binding site [nucleotide binding]
762903003299	error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672
762903003300	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at DnaE2 gene; Region: PHP_PolIIIA_DnaE2; cd07434
762903003301	putative active site [active]
762903003302	putative PHP Thumb interface [polypeptide binding]; other site
762903003303	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
762903003304	generic binding surface II; other site
762903003305	generic binding surface I; other site
762903003306	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
762903003307	active site
762903003308	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08159
762903003309	Putative catalytic NodB homology domain of uncharacterized protein RC0012 from Rickettsia conorii and its bacterial homologs; Region: CE4_RC0012_like; cd10963
762903003310	NodB motif; other site
762903003311	putative active site [active]
762903003312	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
762903003313	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
762903003314	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
762903003315	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
762903003316	putative active site [active]
762903003317	catalytic site [active]
762903003318	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
762903003319	putative active site [active]
762903003320	catalytic site [active]
762903003321	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
762903003322	purine nucleoside phosphorylase; Provisional; Region: PRK08202
762903003323	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
762903003324	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
762903003325	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
762903003326	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
762903003327	N-terminal plug; other site
762903003328	ligand-binding site [chemical binding]; other site
762903003329	hypothetical protein; Provisional; Region: PRK04233
762903003330	SEC-C motif; Region: SEC-C; pfam02810
762903003331	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
762903003332	HI0933-like protein; Region: HI0933_like; pfam03486
762903003333	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
762903003334	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
762903003335	NADH dehydrogenase subunit B; Validated; Region: PRK06411
762903003336	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
762903003337	ATP-grasp domain; Region: ATP-grasp; pfam02222
762903003338	AIR carboxylase; Region: AIRC; pfam00731
762903003339	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
762903003340	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
762903003341	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
762903003342	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
762903003343	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
762903003344	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
762903003345	NADH dehydrogenase subunit D; Validated; Region: PRK06075
762903003346	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903003347	non-specific DNA binding site [nucleotide binding]; other site
762903003348	salt bridge; other site
762903003349	sequence-specific DNA binding site [nucleotide binding]; other site
762903003350	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
762903003351	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
762903003352	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
762903003353	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
762903003354	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
762903003355	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903003356	S-adenosylmethionine binding site [chemical binding]; other site
762903003357	triosephosphate isomerase; Provisional; Region: PRK14567
762903003358	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
762903003359	substrate binding site [chemical binding]; other site
762903003360	dimer interface [polypeptide binding]; other site
762903003361	catalytic triad [active]
762903003362	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: alt_bact_glmU; TIGR03991
762903003363	Sugar nucleotidyl transferase; Region: NTP_transf_4; pfam13562
762903003364	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
762903003365	putative trimer interface [polypeptide binding]; other site
762903003366	putative CoA binding site [chemical binding]; other site
762903003367	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
762903003368	cysteine desulfurase; Provisional; Region: PRK14012
762903003369	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
762903003370	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
762903003371	catalytic residue [active]
762903003372	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
762903003373	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
762903003374	trimerization site [polypeptide binding]; other site
762903003375	active site
762903003376	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
762903003377	Surface antigen; Region: Bac_surface_Ag; pfam01103
762903003378	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
762903003379	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
762903003380	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
762903003381	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
762903003382	putative hydrophobic ligand binding site [chemical binding]; other site
762903003383	Domain of unknown function (DUF377); Region: DUF377; pfam04041
762903003384	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
762903003385	active site
762903003386	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
762903003387	FAD binding pocket [chemical binding]; other site
762903003388	conserved FAD binding motif [chemical binding]; other site
762903003389	phosphate binding motif [ion binding]; other site
762903003390	beta-alpha-beta structure motif; other site
762903003391	NAD binding pocket [chemical binding]; other site
762903003392	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
762903003393	DNA helicase, putative; Region: TIGR00376
762903003394	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903003395	ATP binding site [chemical binding]; other site
762903003396	putative Mg++ binding site [ion binding]; other site
762903003397	AAA domain; Region: AAA_12; pfam13087
762903003398	Domain of unknown function (DUF4114); Region: DUF4114; pfam13448
762903003399	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
762903003400	anti sigma factor interaction site; other site
762903003401	regulatory phosphorylation site [posttranslational modification]; other site
762903003402	Response regulator receiver domain; Region: Response_reg; pfam00072
762903003403	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903003404	active site
762903003405	phosphorylation site [posttranslational modification]
762903003406	intermolecular recognition site; other site
762903003407	dimerization interface [polypeptide binding]; other site
762903003408	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
762903003409	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
762903003410	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
762903003411	Probable Catalytic site; other site
762903003412	metal-binding site
762903003413	CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; Region: CESA_like_1; cd06439
762903003414	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903003415	DXD motif; other site
762903003416	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
762903003417	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
762903003418	ATP binding site [chemical binding]; other site
762903003419	substrate interface [chemical binding]; other site
762903003420	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
762903003421	active site residue [active]
762903003422	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
762903003423	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903003424	FeS/SAM binding site; other site
762903003425	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
762903003426	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
762903003427	ThiS interaction site; other site
762903003428	putative active site [active]
762903003429	tetramer interface [polypeptide binding]; other site
762903003430	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
762903003431	thiamine phosphate binding site [chemical binding]; other site
762903003432	active site
762903003433	pyrophosphate binding site [ion binding]; other site
762903003434	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
762903003435	dimer interface [polypeptide binding]; other site
762903003436	substrate binding site [chemical binding]; other site
762903003437	ATP binding site [chemical binding]; other site
762903003438	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
762903003439	thiamine phosphate binding site [chemical binding]; other site
762903003440	active site
762903003441	pyrophosphate binding site [ion binding]; other site
762903003442	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
762903003443	ThiC-associated domain; Region: ThiC-associated; pfam13667
762903003444	ThiC family; Region: ThiC; pfam01964
762903003445	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
762903003446	thiS-thiF/thiG interaction site; other site
762903003447	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
762903003448	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
762903003449	motif 1; other site
762903003450	active site
762903003451	motif 2; other site
762903003452	motif 3; other site
762903003453	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
762903003454	DHHA1 domain; Region: DHHA1; pfam02272
762903003455	Domain of unknown function (DUF4251); Region: DUF4251; pfam14059
762903003456	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
762903003457	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
762903003458	FAD binding pocket [chemical binding]; other site
762903003459	FAD binding motif [chemical binding]; other site
762903003460	phosphate binding motif [ion binding]; other site
762903003461	beta-alpha-beta structure motif; other site
762903003462	NAD(p) ribose binding residues [chemical binding]; other site
762903003463	NAD binding pocket [chemical binding]; other site
762903003464	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
762903003465	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
762903003466	catalytic loop [active]
762903003467	iron binding site [ion binding]; other site
762903003468	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903003469	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903003470	dimer interface [polypeptide binding]; other site
762903003471	phosphorylation site [posttranslational modification]
762903003472	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903003473	ATP binding site [chemical binding]; other site
762903003474	Mg2+ binding site [ion binding]; other site
762903003475	G-X-G motif; other site
762903003476	Pirin-related protein [General function prediction only]; Region: COG1741
762903003477	Pirin; Region: Pirin; pfam02678
762903003478	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
762903003479	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
762903003480	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
762903003481	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
762903003482	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
762903003483	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
762903003484	substrate binding site [chemical binding]; other site
762903003485	active site
762903003486	catalytic residues [active]
762903003487	heterodimer interface [polypeptide binding]; other site
762903003488	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
762903003489	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
762903003490	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903003491	catalytic residue [active]
762903003492	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
762903003493	active site
762903003494	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
762903003495	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
762903003496	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
762903003497	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903003498	short chain dehydrogenase; Provisional; Region: PRK06181
762903003499	NAD(P) binding site [chemical binding]; other site
762903003500	active site
762903003501	recombination protein RecR; Reviewed; Region: recR; PRK00076
762903003502	RecR protein; Region: RecR; pfam02132
762903003503	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
762903003504	putative active site [active]
762903003505	putative metal-binding site [ion binding]; other site
762903003506	tetramer interface [polypeptide binding]; other site
762903003507	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
762903003508	Late embryogenesis abundant protein; Region: LEA_2; pfam03168
762903003509	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
762903003510	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
762903003511	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
762903003512	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
762903003513	Transcriptional regulator [Transcription]; Region: LysR; COG0583
762903003514	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
762903003515	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
762903003516	putative dimerization interface [polypeptide binding]; other site
762903003517	Predicted membrane protein [Function unknown]; Region: COG2855
762903003518	Methyltransferase domain; Region: Methyltransf_31; pfam13847
762903003519	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903003520	S-adenosylmethionine binding site [chemical binding]; other site
762903003521	MepB protein; Region: MepB; cl01985
762903003522	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903003523	Coenzyme A binding pocket [chemical binding]; other site
762903003524	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
762903003525	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
762903003526	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
762903003527	E3 interaction surface; other site
762903003528	lipoyl attachment site [posttranslational modification]; other site
762903003529	e3 binding domain; Region: E3_binding; pfam02817
762903003530	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
762903003531	competence damage-inducible protein A; Provisional; Region: PRK00549
762903003532	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
762903003533	putative MPT binding site; other site
762903003534	Competence-damaged protein; Region: CinA; pfam02464
762903003535	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
762903003536	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
762903003537	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
762903003538	active site
762903003539	metal binding site [ion binding]; metal-binding site
762903003540	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
762903003541	mce related protein; Region: MCE; pfam02470
762903003542	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
762903003543	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
762903003544	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903003545	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903003546	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
762903003547	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
762903003548	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
762903003549	E3 interaction surface; other site
762903003550	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903003551	lipoyl attachment site [posttranslational modification]; other site
762903003552	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903003553	Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838
762903003554	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
762903003555	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
762903003556	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
762903003557	putative active site [active]
762903003558	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
762903003559	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
762903003560	active site
762903003561	Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192
762903003562	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
762903003563	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
762903003564	Phytochrome region; Region: PHY; pfam00360
762903003565	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903003566	dimer interface [polypeptide binding]; other site
762903003567	phosphorylation site [posttranslational modification]
762903003568	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903003569	ATP binding site [chemical binding]; other site
762903003570	Mg2+ binding site [ion binding]; other site
762903003571	G-X-G motif; other site
762903003572	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
762903003573	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903003574	active site
762903003575	phosphorylation site [posttranslational modification]
762903003576	intermolecular recognition site; other site
762903003577	dimerization interface [polypeptide binding]; other site
762903003578	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
762903003579	DNA binding residues [nucleotide binding]
762903003580	dimerization interface [polypeptide binding]; other site
762903003581	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
762903003582	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
762903003583	trmE is a tRNA modification GTPase; Region: trmE; cd04164
762903003584	G1 box; other site
762903003585	GTP/Mg2+ binding site [chemical binding]; other site
762903003586	Switch I region; other site
762903003587	G2 box; other site
762903003588	Switch II region; other site
762903003589	G3 box; other site
762903003590	G4 box; other site
762903003591	G5 box; other site
762903003592	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
762903003593	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903003594	PAS domain; Region: PAS_9; pfam13426
762903003595	putative active site [active]
762903003596	heme pocket [chemical binding]; other site
762903003597	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
762903003598	Nudix hydrolase homolog; Region: PLN02791
762903003599	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
762903003600	FAD binding pocket [chemical binding]; other site
762903003601	conserved FAD binding motif [chemical binding]; other site
762903003602	phosphate binding motif [ion binding]; other site
762903003603	beta-alpha-beta structure motif; other site
762903003604	NAD binding pocket [chemical binding]; other site
762903003605	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
762903003606	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
762903003607	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
762903003608	ApbE family; Region: ApbE; pfam02424
762903003609	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903003610	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903003611	Uncharacterized conserved protein [Function unknown]; Region: COG1262
762903003612	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
762903003613	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
762903003614	Cytochrome c; Region: Cytochrom_C; cl11414
762903003615	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
762903003616	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
762903003617	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
762903003618	Cu(I) binding site [ion binding]; other site
762903003619	Cytochrome c; Region: Cytochrom_C; pfam00034
762903003620	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
762903003621	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
762903003622	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903003623	active site
762903003624	phosphorylation site [posttranslational modification]
762903003625	intermolecular recognition site; other site
762903003626	dimerization interface [polypeptide binding]; other site
762903003627	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903003628	Walker A motif; other site
762903003629	ATP binding site [chemical binding]; other site
762903003630	Walker B motif; other site
762903003631	arginine finger; other site
762903003632	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
762903003633	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
762903003634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903003635	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
762903003636	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like6; cd05664
762903003637	metal binding site [ion binding]; metal-binding site
762903003638	putative dimer interface [polypeptide binding]; other site
762903003639	Predicted membrane protein [Function unknown]; Region: COG2860
762903003640	UPF0126 domain; Region: UPF0126; pfam03458
762903003641	UPF0126 domain; Region: UPF0126; pfam03458
762903003642	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
762903003643	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
762903003644	Phosphotransferase enzyme family; Region: APH; pfam01636
762903003645	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
762903003646	active site
762903003647	ATP binding site [chemical binding]; other site
762903003648	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
762903003649	substrate binding site [chemical binding]; other site
762903003650	GTP-binding protein LepA; Provisional; Region: PRK05433
762903003651	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
762903003652	G1 box; other site
762903003653	putative GEF interaction site [polypeptide binding]; other site
762903003654	GTP/Mg2+ binding site [chemical binding]; other site
762903003655	Switch I region; other site
762903003656	G2 box; other site
762903003657	G3 box; other site
762903003658	Switch II region; other site
762903003659	G4 box; other site
762903003660	G5 box; other site
762903003661	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
762903003662	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
762903003663	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
762903003664	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14185
762903003665	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
762903003666	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
762903003667	homodimer interface [polypeptide binding]; other site
762903003668	NADP binding site [chemical binding]; other site
762903003669	substrate binding site [chemical binding]; other site
762903003670	RibD C-terminal domain; Region: RibD_C; cl17279
762903003671	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
762903003672	Predicted membrane protein [Function unknown]; Region: COG3059
762903003673	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
762903003674	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903003675	putative metal binding site [ion binding]; other site
762903003676	probable DNA metabolism protein; Region: SAM_7_link_chp; TIGR03915
762903003677	putative DNA modification/repair radical SAM protein; Region: rSAM_link_UDG; TIGR03916
762903003678	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903003679	FeS/SAM binding site; other site
762903003680	putative exonuclease, DNA ligase-associated; Region: Xnuc_lig_assoc; TIGR04122
762903003681	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
762903003682	ATP-dependent DNA ligase; Validated; Region: PRK09247
762903003683	Adenylation domain of putative bacterial ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_Bac1; cd07897
762903003684	active site
762903003685	DNA binding site [nucleotide binding]
762903003686	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of archaeal and bacterial ATP-dependent DNA ligases is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_Arch_LigB; cd07972
762903003687	DNA binding site [nucleotide binding]
762903003688	DEXH box helicase, DNA ligase-associated; Region: DEXH_lig_assoc; TIGR04121
762903003689	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903003690	ATP binding site [chemical binding]; other site
762903003691	putative Mg++ binding site [ion binding]; other site
762903003692	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903003693	nucleotide binding region [chemical binding]; other site
762903003694	ATP-binding site [chemical binding]; other site
762903003695	DEAD/H associated; Region: DEAD_assoc; pfam08494
762903003696	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903003697	Pyrococcus furiosus PF1019 and related proteins, metallophosphatase domain; Region: MPP_PF1019; cd07391
762903003698	putative active site [active]
762903003699	putative metal binding site [ion binding]; other site
762903003700	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
762903003701	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
762903003702	putative dimer interface [polypeptide binding]; other site
762903003703	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
762903003704	active site
762903003705	Dihydroneopterin aldolase; Region: FolB; smart00905
762903003706	active site
762903003707	Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins; Region: SRPBCC_Aha1; cd08892
762903003708	putative hydrophobic ligand binding site [chemical binding]; other site
762903003709	putative Hsp90 binding residues [polypeptide binding]; other site
762903003710	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
762903003711	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
762903003712	active site
762903003713	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
762903003714	substrate binding site [chemical binding]; other site
762903003715	catalytic residues [active]
762903003716	dimer interface [polypeptide binding]; other site
762903003717	aspartate kinase III; Validated; Region: PRK09084
762903003718	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
762903003719	putative catalytic residues [active]
762903003720	nucleotide binding site [chemical binding]; other site
762903003721	aspartate binding site [chemical binding]; other site
762903003722	ACT domains located C-terminal to the catalytic domain of  the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC-like_1; cd04912
762903003723	dimer interface [polypeptide binding]; other site
762903003724	allosteric regulatory binding pocket; other site
762903003725	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
762903003726	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
762903003727	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
762903003728	active site
762903003729	substrate binding site [chemical binding]; other site
762903003730	metal binding site [ion binding]; metal-binding site
762903003731	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
762903003732	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
762903003733	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
762903003734	ribulokinase; Provisional; Region: PRK04123
762903003735	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
762903003736	N- and C-terminal domain interface [polypeptide binding]; other site
762903003737	active site
762903003738	MgATP binding site [chemical binding]; other site
762903003739	catalytic site [active]
762903003740	metal binding site [ion binding]; metal-binding site
762903003741	carbohydrate binding site [chemical binding]; other site
762903003742	homodimer interface [polypeptide binding]; other site
762903003743	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
762903003744	hexamer (dimer of trimers) interface [polypeptide binding]; other site
762903003745	trimer interface [polypeptide binding]; other site
762903003746	substrate binding site [chemical binding]; other site
762903003747	Mn binding site [ion binding]; other site
762903003748	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
762903003749	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903003750	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903003751	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
762903003752	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
762903003753	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
762903003754	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
762903003755	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
762903003756	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
762903003757	quinone interaction residues [chemical binding]; other site
762903003758	active site
762903003759	catalytic residues [active]
762903003760	FMN binding site [chemical binding]; other site
762903003761	substrate binding site [chemical binding]; other site
762903003762	Putative catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases which consist of a 5-stranded beta/alpha barrel; Region: CE4_DAC_u3_5s; cd10972
762903003763	putative active site [active]
762903003764	putative metal binding site [ion binding]; other site
762903003765	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
762903003766	ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Region: NrdJ_Z; TIGR02504
762903003767	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
762903003768	active site
762903003769	dimer interface [polypeptide binding]; other site
762903003770	effector binding site; other site
762903003771	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
762903003772	TSCPD domain; Region: TSCPD; cl14834
762903003773	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
762903003774	Beta-lactamase; Region: Beta-lactamase; pfam00144
762903003775	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903003776	TPR motif; other site
762903003777	binding surface
762903003778	Tetratricopeptide repeat; Region: TPR_16; pfam13432
762903003779	Alginate lyase; Region: Alginate_lyase; pfam05426
762903003780	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903003781	SusD family; Region: SusD; pfam07980
762903003782	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903003783	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903003784	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903003785	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903003786	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
762903003787	DNA polymerase III, delta subunit; Region: holA; TIGR01128
762903003788	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
762903003789	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
762903003790	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903003791	active site
762903003792	HIGH motif; other site
762903003793	nucleotide binding site [chemical binding]; other site
762903003794	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
762903003795	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
762903003796	active site
762903003797	KMSKS motif; other site
762903003798	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
762903003799	tRNA binding surface [nucleotide binding]; other site
762903003800	anticodon binding site; other site
762903003801	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
762903003802	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
762903003803	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
762903003804	active site
762903003805	Zn binding site [ion binding]; other site
762903003806	Dodecin; Region: Dodecin; pfam07311
762903003807	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
762903003808	active site residue [active]
762903003809	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
762903003810	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
762903003811	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
762903003812	active site
762903003813	dimer interface [polypeptide binding]; other site
762903003814	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
762903003815	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
762903003816	putative active site [active]
762903003817	catalytic site [active]
762903003818	putative metal binding site [ion binding]; other site
762903003819	oligomer interface [polypeptide binding]; other site
762903003820	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
762903003821	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
762903003822	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
762903003823	active site
762903003824	Bacteroidetes-Associated Carbohydrate-binding Often N-terminal; Region: BACON; pfam13004
762903003825	Periplasmic copper-binding protein (NosD); Region: NosD; pfam05048
762903003826	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
762903003827	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
762903003828	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903003829	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903003830	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903003831	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903003832	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903003833	FecR protein; Region: FecR; pfam04773
762903003834	RibD C-terminal domain; Region: RibD_C; cl17279
762903003835	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903003836	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903003837	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903003838	DNA binding residues [nucleotide binding]
762903003839	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
762903003840	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
762903003841	putative active site [active]
762903003842	catalytic site [active]
762903003843	putative metal binding site [ion binding]; other site
762903003844	oligomer interface [polypeptide binding]; other site
762903003845	NHL repeat; Region: NHL; pfam01436
762903003846	NHL repeat; Region: NHL; pfam01436
762903003847	NHL repeat; Region: NHL; pfam01436
762903003848	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903003849	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
762903003850	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
762903003851	active site
762903003852	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
762903003853	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
762903003854	putative catalytic site [active]
762903003855	putative metal binding site [ion binding]; other site
762903003856	putative phosphate binding site [ion binding]; other site
762903003857	IPT/TIG domain; Region: TIG; pfam01833
762903003858	NHL repeat; Region: NHL; pfam01436
762903003859	NHL repeat; Region: NHL; pfam01436
762903003860	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
762903003861	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903003862	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903003863	Secretin and TonB N terminus short domain; Region: STN; pfam07660
762903003864	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903003865	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903003866	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903003867	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903003868	FecR protein; Region: FecR; pfam04773
762903003869	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903003870	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903003871	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903003872	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903003873	DNA binding residues [nucleotide binding]
762903003874	Cupin-like domain; Region: Cupin_8; pfam13621
762903003875	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
762903003876	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
762903003877	dimer interface [polypeptide binding]; other site
762903003878	putative anticodon binding site; other site
762903003879	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
762903003880	motif 1; other site
762903003881	active site
762903003882	motif 2; other site
762903003883	motif 3; other site
762903003884	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
762903003885	MgtE intracellular N domain; Region: MgtE_N; pfam03448
762903003886	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
762903003887	Divalent cation transporter; Region: MgtE; pfam01769
762903003888	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
762903003889	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
762903003890	Int/Topo IB signature motif; other site
762903003891	Domain of unknown function (DUF932); Region: DUF932; pfam06067
762903003892	RES domain; Region: RES; pfam08808
762903003893	Bacteriophage abortive infection AbiH; Region: AbiH; pfam14253
762903003894	Response regulator receiver domain; Region: Response_reg; pfam00072
762903003895	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903003896	active site
762903003897	phosphorylation site [posttranslational modification]
762903003898	intermolecular recognition site; other site
762903003899	dimerization interface [polypeptide binding]; other site
762903003900	Helix-turn-helix domain; Region: HTH_17; pfam12728
762903003901	Helix-turn-helix domain; Region: HTH_17; pfam12728
762903003902	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
762903003903	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903003904	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903003905	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903003906	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
762903003907	Conjugative transposon protein TraO; Region: TraO; pfam10626
762903003908	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
762903003909	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
762903003910	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
762903003911	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
762903003912	Protein of unknown function (DUF3989); Region: DUF3989; pfam13150
762903003913	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
762903003914	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
762903003915	Domain of unknown function (DUF4141); Region: DUF4141; pfam13605
762903003916	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
762903003917	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
762903003918	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903003919	Walker A/P-loop; other site
762903003920	ATP binding site [chemical binding]; other site
762903003921	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
762903003922	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
762903003923	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
762903003924	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903003925	non-specific DNA binding site [nucleotide binding]; other site
762903003926	salt bridge; other site
762903003927	sequence-specific DNA binding site [nucleotide binding]; other site
762903003928	Predicted ATPase [General function prediction only]; Region: COG5293
762903003929	Uncharacterized protein conserved in bacteria (DUF2326); Region: DUF2326; pfam10088
762903003930	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903003931	Walker A/P-loop; other site
762903003932	ATP binding site [chemical binding]; other site
762903003933	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
762903003934	putative active site [active]
762903003935	putative metal-binding site [ion binding]; other site
762903003936	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
762903003937	Part of AAA domain; Region: AAA_19; pfam13245
762903003938	Family description; Region: UvrD_C_2; pfam13538
762903003939	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
762903003940	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
762903003941	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
762903003942	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
762903003943	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
762903003944	dimerization interface [polypeptide binding]; other site
762903003945	putative DNA binding site [nucleotide binding]; other site
762903003946	putative Zn2+ binding site [ion binding]; other site
762903003947	MerT mercuric transport protein; Region: MerT; cl03578
762903003948	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
762903003949	metal-binding site [ion binding]
762903003950	peptide chain release factor 1; Provisional; Region: PRK04011
762903003951	YWFCY protein; Region: YWFCY; pfam14293
762903003952	AAA-like domain; Region: AAA_10; pfam12846
762903003953	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
762903003954	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
762903003955	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903003956	active site
762903003957	phosphorylation site [posttranslational modification]
762903003958	intermolecular recognition site; other site
762903003959	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903003960	Walker B motif; other site
762903003961	arginine finger; other site
762903003962	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
762903003963	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
762903003964	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
762903003965	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
762903003966	Soluble P-type ATPase [General function prediction only]; Region: COG4087
762903003967	potassium-transporting ATPase subunit C; Provisional; Region: PRK14002
762903003968	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
762903003969	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
762903003970	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
762903003971	Ligand Binding Site [chemical binding]; other site
762903003972	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
762903003973	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
762903003974	dimerization interface [polypeptide binding]; other site
762903003975	PAS domain; Region: PAS; smart00091
762903003976	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903003977	dimer interface [polypeptide binding]; other site
762903003978	phosphorylation site [posttranslational modification]
762903003979	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903003980	ATP binding site [chemical binding]; other site
762903003981	Mg2+ binding site [ion binding]; other site
762903003982	G-X-G motif; other site
762903003983	RteC protein; Region: RteC; pfam09357
762903003984	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903003985	S-adenosylmethionine binding site [chemical binding]; other site
762903003986	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
762903003987	DEAD-like helicases superfamily; Region: DEXDc; smart00487
762903003988	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
762903003989	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
762903003990	helicase superfamily c-terminal domain; Region: HELICc; smart00490
762903003991	ATP-binding site [chemical binding]; other site
762903003992	Domain of unknown function (DUF1896); Region: DUF1896; pfam08989
762903003993	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903003994	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903003995	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
762903003996	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
762903003997	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
762903003998	metal-binding site [ion binding]
762903003999	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
762903004000	Soluble P-type ATPase [General function prediction only]; Region: COG4087
762903004001	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
762903004002	metal-binding site [ion binding]
762903004003	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cl00323
762903004004	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
762903004005	metal-binding site [ion binding]
762903004006	Protein of unknown function (DUF3347); Region: DUF3347; pfam11827
762903004007	Domain of unknown function (DUF305); Region: DUF305; cl17794
762903004008	Protein of unknown function (DUF3347); Region: DUF3347; pfam11827
762903004009	Haem-binding domain; Region: Haem_bd; pfam14376
762903004010	copper-resistance protein, CopA family; Region: copper_res_A; TIGR01480
762903004011	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
762903004012	Multicopper oxidase; Region: Cu-oxidase; pfam00394
762903004013	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
762903004014	ORF6N domain; Region: ORF6N; pfam10543
762903004015	DNA topoisomerase III; Provisional; Region: PRK07726
762903004016	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
762903004017	active site
762903004018	putative interdomain interaction site [polypeptide binding]; other site
762903004019	putative metal-binding site [ion binding]; other site
762903004020	putative nucleotide binding site [chemical binding]; other site
762903004021	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
762903004022	domain I; other site
762903004023	DNA binding groove [nucleotide binding]
762903004024	phosphate binding site [ion binding]; other site
762903004025	domain II; other site
762903004026	domain III; other site
762903004027	nucleotide binding site [chemical binding]; other site
762903004028	catalytic site [active]
762903004029	domain IV; other site
762903004030	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
762903004031	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
762903004032	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
762903004033	Helix-turn-helix domain; Region: HTH_17; pfam12728
762903004034	Helix-turn-helix domain; Region: HTH_17; pfam12728
762903004035	RteC protein; Region: RteC; pfam09357
762903004036	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
762903004037	Methyltransferase domain; Region: Methyltransf_31; pfam13847
762903004038	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903004039	S-adenosylmethionine binding site [chemical binding]; other site
762903004040	META domain; Region: META; pfam03724
762903004041	NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.  Rhizobium and related species form nodules on the roots of their...; Region: NodN; cd03450
762903004042	putative active site [active]
762903004043	putative catalytic site [active]
762903004044	Rrf2 family protein; Region: rrf2_super; TIGR00738
762903004045	Transcriptional regulator; Region: Rrf2; pfam02082
762903004046	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903004047	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903004048	active site
762903004049	phosphorylation site [posttranslational modification]
762903004050	intermolecular recognition site; other site
762903004051	dimerization interface [polypeptide binding]; other site
762903004052	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
762903004053	DNA binding site [nucleotide binding]
762903004054	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
762903004055	HAMP domain; Region: HAMP; pfam00672
762903004056	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903004057	ATP binding site [chemical binding]; other site
762903004058	Mg2+ binding site [ion binding]; other site
762903004059	G-X-G motif; other site
762903004060	Outer membrane efflux protein; Region: OEP; pfam02321
762903004061	Outer membrane efflux protein; Region: OEP; pfam02321
762903004062	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903004063	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903004064	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903004065	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
762903004066	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
762903004067	Ferritin-like domain; Region: Ferritin; pfam00210
762903004068	ferroxidase diiron center [ion binding]; other site
762903004069	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; smart00782
762903004070	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
762903004071	PhnA protein; Region: PhnA; pfam03831
762903004072	MFS transport protein AraJ; Provisional; Region: PRK10091
762903004073	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903004074	putative substrate translocation pore; other site
762903004075	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
762903004076	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
762903004077	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
762903004078	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
762903004079	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
762903004080	dimer interface [polypeptide binding]; other site
762903004081	active site
762903004082	heme binding site [chemical binding]; other site
762903004083	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
762903004084	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
762903004085	Beta-lactamase; Region: Beta-lactamase; pfam00144
762903004086	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903004087	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903004088	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903004089	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
762903004090	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903004091	SusD family; Region: SusD; pfam07980
762903004092	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
762903004093	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
762903004094	conserved cys residue [active]
762903004095	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903004096	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903004097	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_4; cd08897
762903004098	putative hydrophobic ligand binding site [chemical binding]; other site
762903004099	DoxX-like family; Region: DoxX_2; pfam13564
762903004100	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
762903004101	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_2; cd08895
762903004102	putative hydrophobic ligand binding site [chemical binding]; other site
762903004103	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
762903004104	active site
762903004105	RteC protein; Region: RteC; pfam09357
762903004106	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
762903004107	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
762903004108	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
762903004109	DNA topoisomerase III; Provisional; Region: PRK07726
762903004110	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
762903004111	active site
762903004112	putative interdomain interaction site [polypeptide binding]; other site
762903004113	putative metal-binding site [ion binding]; other site
762903004114	putative nucleotide binding site [chemical binding]; other site
762903004115	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
762903004116	domain I; other site
762903004117	DNA binding groove [nucleotide binding]
762903004118	phosphate binding site [ion binding]; other site
762903004119	domain II; other site
762903004120	domain III; other site
762903004121	nucleotide binding site [chemical binding]; other site
762903004122	catalytic site [active]
762903004123	domain IV; other site
762903004124	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
762903004125	Ribosomal RNA adenine dimethylase; Region: RrnaAD; pfam00398
762903004126	Ribosomal RNA adenine dimethylases; Region: rADc; smart00650
762903004127	RteC protein; Region: RteC; pfam09357
762903004128	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
762903004129	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903004130	Coenzyme A binding pocket [chemical binding]; other site
762903004131	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
762903004132	active site
762903004133	catalytic residues [active]
762903004134	metal binding site [ion binding]; metal-binding site
762903004135	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903004136	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903004137	ligand binding site [chemical binding]; other site
762903004138	flexible hinge region; other site
762903004139	Transposase domain (DUF772); Region: DUF772; pfam05598
762903004140	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
762903004141	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
762903004142	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
762903004143	MarR family; Region: MarR_2; pfam12802
762903004144	O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315
762903004145	Leucine carboxyl methyltransferase; Region: LCM; pfam04072
762903004146	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
762903004147	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903004148	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903004149	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903004150	AAA domain; Region: AAA_33; pfam13671
762903004151	AAA domain; Region: AAA_17; pfam13207
762903004152	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
762903004153	Zn2+ binding site [ion binding]; other site
762903004154	Mg2+ binding site [ion binding]; other site
762903004155	YWFCY protein; Region: YWFCY; pfam14293
762903004156	AAA-like domain; Region: AAA_10; pfam12846
762903004157	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
762903004158	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
762903004159	Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard...; Region: Maf_Ham1; cl00276
762903004160	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
762903004161	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
762903004162	P-loop; other site
762903004163	Magnesium ion binding site [ion binding]; other site
762903004164	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
762903004165	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
762903004166	Domain of unknown function DUF87; Region: DUF87; pfam01935
762903004167	HerA helicase [Replication, recombination, and repair]; Region: COG0433
762903004168	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
762903004169	Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs; Region: Piwi_piwi-like_ProArk; cd04659
762903004170	5' RNA guide strand anchoring site; other site
762903004171	active site
762903004172	TIR domain; Region: TIR_2; pfam13676
762903004173	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903004174	non-specific DNA binding site [nucleotide binding]; other site
762903004175	salt bridge; other site
762903004176	sequence-specific DNA binding site [nucleotide binding]; other site
762903004177	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
762903004178	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
762903004179	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
762903004180	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
762903004181	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903004182	Walker A/P-loop; other site
762903004183	ATP binding site [chemical binding]; other site
762903004184	Domain of unknown function (DUF4141); Region: DUF4141; pfam13605
762903004185	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
762903004186	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
762903004187	Protein of unknown function (DUF3989); Region: DUF3989; pfam13150
762903004188	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
762903004189	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
762903004190	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
762903004191	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
762903004192	Conjugative transposon protein TraO; Region: TraO; pfam10626
762903004193	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
762903004194	Response regulator receiver domain; Region: Response_reg; pfam00072
762903004195	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903004196	active site
762903004197	dimerization interface [polypeptide binding]; other site
762903004198	Antirestriction protein (ArdA); Region: ArdA; pfam07275
762903004199	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
762903004200	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
762903004201	catalytic residues [active]
762903004202	catalytic nucleophile [active]
762903004203	Recombinase; Region: Recombinase; pfam07508
762903004204	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
762903004205	TPR repeat; Region: TPR_11; pfam13414
762903004206	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903004207	binding surface
762903004208	TPR motif; other site
762903004209	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903004210	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903004211	binding surface
762903004212	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903004213	TPR motif; other site
762903004214	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903004215	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903004216	binding surface
762903004217	TPR motif; other site
762903004218	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903004219	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903004220	dimer interface [polypeptide binding]; other site
762903004221	phosphorylation site [posttranslational modification]
762903004222	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903004223	ATP binding site [chemical binding]; other site
762903004224	Mg2+ binding site [ion binding]; other site
762903004225	G-X-G motif; other site
762903004226	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
762903004227	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
762903004228	YceI-like domain; Region: YceI; pfam04264
762903004229	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903004230	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
762903004231	N-terminal plug; other site
762903004232	ligand-binding site [chemical binding]; other site
762903004233	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
762903004234	active site
762903004235	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
762903004236	catalytic tetrad [active]
762903004237	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
762903004238	putative active site [active]
762903004239	catalytic residue [active]
762903004240	UGMP family protein; Validated; Region: PRK09604
762903004241	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
762903004242	Family of unknown function (DUF490); Region: DUF490; pfam04357
762903004243	Family of unknown function (DUF490); Region: DUF490; pfam04357
762903004244	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
762903004245	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
762903004246	active site
762903004247	Response regulator receiver domain; Region: Response_reg; pfam00072
762903004248	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903004249	active site
762903004250	phosphorylation site [posttranslational modification]
762903004251	intermolecular recognition site; other site
762903004252	dimerization interface [polypeptide binding]; other site
762903004253	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
762903004254	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903004255	putative active site [active]
762903004256	heme pocket [chemical binding]; other site
762903004257	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903004258	dimer interface [polypeptide binding]; other site
762903004259	phosphorylation site [posttranslational modification]
762903004260	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903004261	ATP binding site [chemical binding]; other site
762903004262	Mg2+ binding site [ion binding]; other site
762903004263	G-X-G motif; other site
762903004264	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903004265	Response regulator receiver domain; Region: Response_reg; pfam00072
762903004266	active site
762903004267	phosphorylation site [posttranslational modification]
762903004268	intermolecular recognition site; other site
762903004269	dimerization interface [polypeptide binding]; other site
762903004270	CheB methylesterase; Region: CheB_methylest; pfam01339
762903004271	Methyltransferase, chemotaxis proteins; Region: MeTrc; smart00138
762903004272	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
762903004273	CHASE3 domain; Region: CHASE3; pfam05227
762903004274	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
762903004275	GAF domain; Region: GAF_3; pfam13492
762903004276	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903004277	dimer interface [polypeptide binding]; other site
762903004278	phosphorylation site [posttranslational modification]
762903004279	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903004280	ATP binding site [chemical binding]; other site
762903004281	Mg2+ binding site [ion binding]; other site
762903004282	G-X-G motif; other site
762903004283	Response regulator receiver domain; Region: Response_reg; pfam00072
762903004284	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903004285	active site
762903004286	phosphorylation site [posttranslational modification]
762903004287	intermolecular recognition site; other site
762903004288	dimerization interface [polypeptide binding]; other site
762903004289	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903004290	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903004291	active site
762903004292	phosphorylation site [posttranslational modification]
762903004293	intermolecular recognition site; other site
762903004294	Response regulator receiver domain; Region: Response_reg; pfam00072
762903004295	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903004296	active site
762903004297	phosphorylation site [posttranslational modification]
762903004298	intermolecular recognition site; other site
762903004299	dimerization interface [polypeptide binding]; other site
762903004300	gliding motility-associated protein GldC; Region: GldC; TIGR03515
762903004301	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
762903004302	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
762903004303	ATP binding site [chemical binding]; other site
762903004304	Mg++ binding site [ion binding]; other site
762903004305	motif III; other site
762903004306	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903004307	nucleotide binding region [chemical binding]; other site
762903004308	ATP-binding site [chemical binding]; other site
762903004309	dihydroorotase; Reviewed; Region: PRK09236
762903004310	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
762903004311	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
762903004312	active site
762903004313	chaperone protein HscA; Provisional; Region: hscA; PRK05183
762903004314	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
762903004315	nucleotide binding site [chemical binding]; other site
762903004316	putative NEF/HSP70 interaction site [polypeptide binding]; other site
762903004317	SBD interface [polypeptide binding]; other site
762903004318	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
762903004319	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
762903004320	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
762903004321	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
762903004322	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
762903004323	histidinol dehydrogenase; Region: hisD; TIGR00069
762903004324	NAD binding site [chemical binding]; other site
762903004325	dimerization interface [polypeptide binding]; other site
762903004326	product binding site; other site
762903004327	substrate binding site [chemical binding]; other site
762903004328	zinc binding site [ion binding]; other site
762903004329	catalytic residues [active]
762903004330	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
762903004331	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
762903004332	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903004333	homodimer interface [polypeptide binding]; other site
762903004334	catalytic residue [active]
762903004335	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
762903004336	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903004337	active site
762903004338	motif I; other site
762903004339	motif II; other site
762903004340	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
762903004341	putative active site pocket [active]
762903004342	4-fold oligomerization interface [polypeptide binding]; other site
762903004343	metal binding residues [ion binding]; metal-binding site
762903004344	3-fold/trimer interface [polypeptide binding]; other site
762903004345	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
762903004346	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
762903004347	putative active site [active]
762903004348	oxyanion strand; other site
762903004349	catalytic triad [active]
762903004350	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
762903004351	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
762903004352	catalytic residues [active]
762903004353	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
762903004354	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
762903004355	substrate binding site [chemical binding]; other site
762903004356	glutamase interaction surface [polypeptide binding]; other site
762903004357	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
762903004358	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
762903004359	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
762903004360	metal binding site [ion binding]; metal-binding site
762903004361	Tudor-like domain present in plant sequences; Region: Agenet; smart00743
762903004362	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
762903004363	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
762903004364	active site
762903004365	metal binding site [ion binding]; metal-binding site
762903004366	nudix motif; other site
762903004367	FOG: WD40 repeat [General function prediction only]; Region: COG2319
762903004368	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
762903004369	structural tetrad; other site
762903004370	Bacterial SH3 domain; Region: SH3_3; pfam08239
762903004371	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
762903004372	NlpC/P60 family; Region: NLPC_P60; pfam00877
762903004373	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
762903004374	Ligand Binding Site [chemical binding]; other site
762903004375	4Fe-4S binding domain; Region: Fer4; pfam00037
762903004376	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
762903004377	cell division ATP-binding protein FtsE; Region: FtsE; TIGR02673
762903004378	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903004379	Walker A/P-loop; other site
762903004380	ATP binding site [chemical binding]; other site
762903004381	Q-loop/lid; other site
762903004382	ABC transporter signature motif; other site
762903004383	Walker B; other site
762903004384	D-loop; other site
762903004385	H-loop/switch region; other site
762903004386	GrpE; Region: GrpE; pfam01025
762903004387	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
762903004388	dimer interface [polypeptide binding]; other site
762903004389	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
762903004390	chaperone protein DnaJ; Provisional; Region: PRK14289
762903004391	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
762903004392	HSP70 interaction site [polypeptide binding]; other site
762903004393	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
762903004394	substrate binding site [polypeptide binding]; other site
762903004395	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
762903004396	Zn binding sites [ion binding]; other site
762903004397	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
762903004398	dimer interface [polypeptide binding]; other site
762903004399	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903004400	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903004401	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
762903004402	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
762903004403	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
762903004404	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
762903004405	ATP-binding cassette domain of an uncharacterized transporter; Region: ABC_putative_ATPase; cd03269
762903004406	Walker A/P-loop; other site
762903004407	ATP binding site [chemical binding]; other site
762903004408	Q-loop/lid; other site
762903004409	ABC transporter signature motif; other site
762903004410	Walker B; other site
762903004411	D-loop; other site
762903004412	H-loop/switch region; other site
762903004413	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
762903004414	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
762903004415	Protein of unknown function (DUF4256); Region: DUF4256; pfam14066
762903004416	exopolyphosphatase; Region: exo_poly_only; TIGR03706
762903004417	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
762903004418	adenylosuccinate lyase; Provisional; Region: PRK09285
762903004419	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
762903004420	tetramer interface [polypeptide binding]; other site
762903004421	active site
762903004422	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
762903004423	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
762903004424	Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069
762903004425	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
762903004426	active site
762903004427	FMN binding site [chemical binding]; other site
762903004428	substrate binding site [chemical binding]; other site
762903004429	3Fe-4S cluster binding site [ion binding]; other site
762903004430	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cd00136
762903004431	C-terminal processing peptidase-like; serine protease family S41; Region: Peptidase_S41_CPP_like; cd07561
762903004432	Catalytic dyad [active]
762903004433	carbamoyl phosphate synthase-like protein; Provisional; Region: PRK12767
762903004434	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
762903004435	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
762903004436	Walker A/P-loop; other site
762903004437	ATP binding site [chemical binding]; other site
762903004438	Q-loop/lid; other site
762903004439	ABC transporter signature motif; other site
762903004440	Walker B; other site
762903004441	D-loop; other site
762903004442	H-loop/switch region; other site
762903004443	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
762903004444	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
762903004445	CoA-ligase; Region: Ligase_CoA; pfam00549
762903004446	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903004447	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903004448	DNA binding site [nucleotide binding]
762903004449	domain linker motif; other site
762903004450	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903004451	dimerization interface [polypeptide binding]; other site
762903004452	ligand binding site [chemical binding]; other site
762903004453	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
762903004454	Domain of unknown function (DUF4112); Region: DUF4112; pfam13430
762903004455	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cl00250
762903004456	30S subunit binding site; other site
762903004457	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
762903004458	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903004459	S-adenosylmethionine binding site [chemical binding]; other site
762903004460	primosome assembly protein PriA; Validated; Region: PRK05580
762903004461	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903004462	ATP binding site [chemical binding]; other site
762903004463	putative Mg++ binding site [ion binding]; other site
762903004464	nucleotide binding region [chemical binding]; other site
762903004465	helicase superfamily c-terminal domain; Region: HELICc; smart00490
762903004466	ATP-binding site [chemical binding]; other site
762903004467	Protein of unknown function (DUF423); Region: DUF423; pfam04241
762903004468	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
762903004469	Glycoprotease family; Region: Peptidase_M22; pfam00814
762903004470	Haemolytic domain; Region: Haemolytic; pfam01809
762903004471	ribonuclease P; Reviewed; Region: rnpA; PRK01903
762903004472	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
762903004473	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
762903004474	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
762903004475	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
762903004476	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
762903004477	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
762903004478	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
762903004479	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
762903004480	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
762903004481	dimerization interface [polypeptide binding]; other site
762903004482	DPS ferroxidase diiron center [ion binding]; other site
762903004483	ion pore; other site
762903004484	Short C-terminal domain; Region: SHOCT; pfam09851
762903004485	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
762903004486	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
762903004487	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903004488	Alkaline and neutral invertase; Region: Glyco_hydro_100; cl17340
762903004489	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
762903004490	catalytic core [active]
762903004491	UbiA prenyltransferase family; Region: UbiA; pfam01040
762903004492	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
762903004493	Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BcsA; COG3424
762903004494	Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy; Region: CHS_like; cd00831
762903004495	malonyl-CoA binding site [chemical binding]; other site
762903004496	dimer interface [polypeptide binding]; other site
762903004497	active site
762903004498	product binding site; other site
762903004499	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903004500	hypothetical protein; Provisional; Region: PRK07236
762903004501	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
762903004502	Methyltransferase domain; Region: Methyltransf_31; pfam13847
762903004503	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903004504	S-adenosylmethionine binding site [chemical binding]; other site
762903004505	Bacteroidetes-specific putative membrane protein; Region: Bac_Flav_fam_1; TIGR03519
762903004506	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
762903004507	FOG: PKD repeat [General function prediction only]; Region: COG3291
762903004508	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
762903004509	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
762903004510	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903004511	Protein of unknown function (DUF458); Region: DUF458; cl00861
762903004512	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
762903004513	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
762903004514	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
762903004515	Cl binding site [ion binding]; other site
762903004516	oligomer interface [polypeptide binding]; other site
762903004517	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
762903004518	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
762903004519	Clp amino terminal domain; Region: Clp_N; pfam02861
762903004520	Clp amino terminal domain; Region: Clp_N; pfam02861
762903004521	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903004522	Walker A motif; other site
762903004523	ATP binding site [chemical binding]; other site
762903004524	Walker B motif; other site
762903004525	arginine finger; other site
762903004526	UvrB/uvrC motif; Region: UVR; pfam02151
762903004527	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903004528	Walker A motif; other site
762903004529	ATP binding site [chemical binding]; other site
762903004530	Walker B motif; other site
762903004531	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
762903004532	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
762903004533	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903004534	Walker A/P-loop; other site
762903004535	ATP binding site [chemical binding]; other site
762903004536	Q-loop/lid; other site
762903004537	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903004538	ABC transporter signature motif; other site
762903004539	Walker B; other site
762903004540	D-loop; other site
762903004541	ABC transporter; Region: ABC_tran_2; pfam12848
762903004542	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903004543	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
762903004544	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
762903004545	active site
762903004546	catalytic tetrad [active]
762903004547	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
762903004548	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903004549	putative substrate translocation pore; other site
762903004550	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
762903004551	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
762903004552	active site
762903004553	dimer interface [polypeptide binding]; other site
762903004554	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903004555	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903004556	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903004557	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903004558	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903004559	DNA binding site [nucleotide binding]
762903004560	domain linker motif; other site
762903004561	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903004562	dimerization interface [polypeptide binding]; other site
762903004563	ligand binding site [chemical binding]; other site
762903004564	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903004565	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903004566	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
762903004567	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
762903004568	active site
762903004569	trimer interface [polypeptide binding]; other site
762903004570	allosteric site; other site
762903004571	active site lid [active]
762903004572	TM1410 hypothetical-related protein; Region: DUF297; cl00997
762903004573	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
762903004574	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
762903004575	active site
762903004576	catalytic triad [active]
762903004577	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
762903004578	active site
762903004579	catalytic triad [active]
762903004580	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903004581	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903004582	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903004583	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903004584	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903004585	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903004586	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903004587	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903004588	DNA binding site [nucleotide binding]
762903004589	domain linker motif; other site
762903004590	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
762903004591	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
762903004592	ligand binding site [chemical binding]; other site
762903004593	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
762903004594	putative ligand binding site [chemical binding]; other site
762903004595	PAS domain S-box; Region: sensory_box; TIGR00229
762903004596	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903004597	putative active site [active]
762903004598	heme pocket [chemical binding]; other site
762903004599	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
762903004600	GAF domain; Region: GAF; pfam01590
762903004601	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903004602	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903004603	dimer interface [polypeptide binding]; other site
762903004604	phosphorylation site [posttranslational modification]
762903004605	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903004606	ATP binding site [chemical binding]; other site
762903004607	Mg2+ binding site [ion binding]; other site
762903004608	G-X-G motif; other site
762903004609	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
762903004610	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903004611	PGAP1-like protein; Region: PGAP1; pfam07819
762903004612	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
762903004613	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903004614	putative substrate translocation pore; other site
762903004615	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
762903004616	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
762903004617	nucleotide binding site [chemical binding]; other site
762903004618	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903004619	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903004620	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903004621	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903004622	dimer interface [polypeptide binding]; other site
762903004623	phosphorylation site [posttranslational modification]
762903004624	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903004625	ATP binding site [chemical binding]; other site
762903004626	Mg2+ binding site [ion binding]; other site
762903004627	G-X-G motif; other site
762903004628	Response regulator receiver domain; Region: Response_reg; pfam00072
762903004629	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903004630	active site
762903004631	phosphorylation site [posttranslational modification]
762903004632	intermolecular recognition site; other site
762903004633	dimerization interface [polypeptide binding]; other site
762903004634	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903004635	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903004636	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
762903004637	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903004638	Sulfatase; Region: Sulfatase; pfam00884
762903004639	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903004640	Sulfatase; Region: Sulfatase; pfam00884
762903004641	Sulfatase; Region: Sulfatase; cl17466
762903004642	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903004643	Sulfatase; Region: Sulfatase; cl17466
762903004644	Sulfatase; Region: Sulfatase; cl17466
762903004645	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
762903004646	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903004647	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903004648	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903004649	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903004650	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903004651	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903004652	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903004653	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
762903004654	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
762903004655	Integrase core domain; Region: rve; pfam00665
762903004656	Integrase core domain; Region: rve_3; pfam13683
762903004657	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903004658	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903004659	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
762903004660	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
762903004661	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
762903004662	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
762903004663	Topoisomerase IB [DNA replication, recombination, and repair]; Region: COG3569
762903004664	DNA topoisomerase IB, C-terminal catalytic domain. Topoisomerase I promotes the relaxation of both positive and negative DNA superhelical tension by introducing a transient single-stranded break in duplex DNA. This function is vital for the processes of...; Region: Topo_IB_C; cd00659
762903004665	active site
762903004666	DNA binding site [nucleotide binding]
762903004667	Int/Topo IB signature motif; other site
762903004668	catalytic residues [active]
762903004669	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
762903004670	Lumazine binding domain; Region: Lum_binding; pfam00677
762903004671	Lumazine binding domain; Region: Lum_binding; pfam00677
762903004672	CcmB protein; Region: CcmB; cl17444
762903004673	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
762903004674	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
762903004675	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
762903004676	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; pfam00208
762903004677	NAD(P) binding site [chemical binding]; other site
762903004678	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903004679	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
762903004680	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
762903004681	nudix motif; other site
762903004682	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
762903004683	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cd00363
762903004684	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
762903004685	active site
762903004686	ADP/pyrophosphate binding site [chemical binding]; other site
762903004687	dimerization interface [polypeptide binding]; other site
762903004688	allosteric effector site; other site
762903004689	fructose-1,6-bisphosphate binding site; other site
762903004690	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903004691	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
762903004692	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
762903004693	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
762903004694	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
762903004695	asparagine synthetase AsnA; Provisional; Region: PRK05425
762903004696	motif 1; other site
762903004697	dimer interface [polypeptide binding]; other site
762903004698	active site
762903004699	motif 2; other site
762903004700	motif 3; other site
762903004701	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
762903004702	DNA protecting protein DprA; Region: dprA; TIGR00732
762903004703	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
762903004704	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
762903004705	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
762903004706	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903004707	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903004708	DNA binding residues [nucleotide binding]
762903004709	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
762903004710	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903004711	active site
762903004712	short chain dehydrogenase; Provisional; Region: PRK06701
762903004713	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
762903004714	NAD binding site [chemical binding]; other site
762903004715	metal binding site [ion binding]; metal-binding site
762903004716	active site
762903004717	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
762903004718	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
762903004719	Predicted permeases [General function prediction only]; Region: COG0795
762903004720	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
762903004721	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
762903004722	EamA-like transporter family; Region: EamA; pfam00892
762903004723	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
762903004724	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
762903004725	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
762903004726	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
762903004727	Protein of unknown function (DUF1697); Region: DUF1697; cl01557
762903004728	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
762903004729	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
762903004730	active site
762903004731	catalytic tetrad [active]
762903004732	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903004733	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903004734	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903004735	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903004736	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
762903004737	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903004738	SusD family; Region: SusD; pfam07980
762903004739	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903004740	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903004741	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903004742	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
762903004743	FAD binding domain; Region: FAD_binding_4; pfam01565
762903004744	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
762903004745	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
762903004746	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
762903004747	Na binding site [ion binding]; other site
762903004748	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
762903004749	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
762903004750	putative active site [active]
762903004751	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
762903004752	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
762903004753	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903004754	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903004755	active site
762903004756	metal binding site [ion binding]; metal-binding site
762903004757	PQQ-like domain; Region: PQQ_2; pfam13360
762903004758	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
762903004759	active site
762903004760	Trp docking motif [polypeptide binding]; other site
762903004761	PQQ-like domain; Region: PQQ_2; pfam13360
762903004762	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
762903004763	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903004764	AMP nucleosidase; Provisional; Region: PRK07115
762903004765	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
762903004766	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
762903004767	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903004768	Walker A motif; other site
762903004769	ATP binding site [chemical binding]; other site
762903004770	Walker B motif; other site
762903004771	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
762903004772	Clp protease; Region: CLP_protease; pfam00574
762903004773	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
762903004774	oligomer interface [polypeptide binding]; other site
762903004775	active site residues [active]
762903004776	trigger factor; Region: tig; TIGR00115
762903004777	EVE domain; Region: EVE; pfam01878
762903004778	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903004779	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903004780	ligand binding site [chemical binding]; other site
762903004781	flexible hinge region; other site
762903004782	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
762903004783	Uncharacterized conserved protein [Function unknown]; Region: COG2128
762903004784	Large family of predicted nucleotide-binding domains; Region: PINc; smart00670
762903004785	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
762903004786	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903004787	non-specific DNA binding site [nucleotide binding]; other site
762903004788	salt bridge; other site
762903004789	sequence-specific DNA binding site [nucleotide binding]; other site
762903004790	Domain of unknown function (DUF955); Region: DUF955; cl01076
762903004791	Domain of unknown function (DUF1508); Region: DUF1508; cl01356
762903004792	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
762903004793	Uncharacterized protein conserved in bacteria (DUF2188); Region: DUF2188; pfam09954
762903004794	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
762903004795	cyclase homology domain; Region: CHD; cd07302
762903004796	nucleotidyl binding site; other site
762903004797	metal binding site [ion binding]; metal-binding site
762903004798	dimer interface [polypeptide binding]; other site
762903004799	SEC-C motif; Region: SEC-C; pfam02810
762903004800	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
762903004801	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
762903004802	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903004803	ATP binding site [chemical binding]; other site
762903004804	putative Mg++ binding site [ion binding]; other site
762903004805	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
762903004806	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
762903004807	HsdM N-terminal domain; Region: HsdM_N; pfam12161
762903004808	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
762903004809	Methyltransferase domain; Region: Methyltransf_26; pfam13659
762903004810	VirE N-terminal domain; Region: VirE_N; pfam08800
762903004811	Primase C terminal 1 (PriCT-1); Region: PriCT_1; cl07362
762903004812	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
762903004813	Helix-turn-helix domain; Region: HTH_17; pfam12728
762903004814	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
762903004815	arsenical-resistance protein; Region: acr3; TIGR00832
762903004816	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
762903004817	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
762903004818	dimerization interface [polypeptide binding]; other site
762903004819	putative DNA binding site [nucleotide binding]; other site
762903004820	putative Zn2+ binding site [ion binding]; other site
762903004821	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
762903004822	active site
762903004823	DNA binding site [nucleotide binding]
762903004824	Int/Topo IB signature motif; other site
762903004825	Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; Region: CASc; cl00042
762903004826	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
762903004827	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
762903004828	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
762903004829	putative dimer interface [polypeptide binding]; other site
762903004830	Protein of unknown function (DUF1569); Region: DUF1569; pfam07606
762903004831	Protein of unknown function (DUF493); Region: DUF493; pfam04359
762903004832	maltose O-acetyltransferase; Provisional; Region: PRK10092
762903004833	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
762903004834	active site
762903004835	substrate binding site [chemical binding]; other site
762903004836	trimer interface [polypeptide binding]; other site
762903004837	CoA binding site [chemical binding]; other site
762903004838	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903004839	TPR motif; other site
762903004840	TPR repeat; Region: TPR_11; pfam13414
762903004841	binding surface
762903004842	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
762903004843	Found in ATP-dependent protease La (LON); Region: LON; smart00464
762903004844	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903004845	Walker A motif; other site
762903004846	ATP binding site [chemical binding]; other site
762903004847	Walker B motif; other site
762903004848	arginine finger; other site
762903004849	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
762903004850	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
762903004851	Ligand Binding Site [chemical binding]; other site
762903004852	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
762903004853	Ligand Binding Site [chemical binding]; other site
762903004854	Uncharacterized protein conserved in bacteria (DUF2219); Region: DUF2219; pfam09982
762903004855	cytidylate kinase; Provisional; Region: cmk; PRK00023
762903004856	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
762903004857	CMP-binding site; other site
762903004858	The sites determining sugar specificity; other site
762903004859	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
762903004860	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
762903004861	RNA binding site [nucleotide binding]; other site
762903004862	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
762903004863	RNA binding site [nucleotide binding]; other site
762903004864	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
762903004865	RNA binding site [nucleotide binding]; other site
762903004866	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
762903004867	RNA binding site [nucleotide binding]; other site
762903004868	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
762903004869	RNA binding site [nucleotide binding]; other site
762903004870	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
762903004871	RNA binding site [nucleotide binding]; other site
762903004872	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
762903004873	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
762903004874	active site
762903004875	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
762903004876	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
762903004877	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
762903004878	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
762903004879	putative active site [active]
762903004880	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
762903004881	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
762903004882	binding surface
762903004883	TPR motif; other site
762903004884	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903004885	Sporulation related domain; Region: SPOR; cl10051
762903004886	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
762903004887	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
762903004888	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
762903004889	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
762903004890	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
762903004891	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
762903004892	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
762903004893	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
762903004894	four helix bundle protein; Region: TIGR02436
762903004895	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
762903004896	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
762903004897	putative active site; other site
762903004898	catalytic triad [active]
762903004899	putative dimer interface [polypeptide binding]; other site
762903004900	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
762903004901	membrane-bound proton-translocating pyrophosphatase; Validated; Region: hppA; PRK00733
762903004902	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
762903004903	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
762903004904	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
762903004905	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
762903004906	active site
762903004907	amino acid transporter; Region: 2A0306; TIGR00909
762903004908	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
762903004909	MarC family integral membrane protein; Region: MarC; pfam01914
762903004910	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
762903004911	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903004912	S-adenosylmethionine binding site [chemical binding]; other site
762903004913	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
762903004914	ligand binding site [chemical binding]; other site
762903004915	GMP synthase; Reviewed; Region: guaA; PRK00074
762903004916	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
762903004917	AMP/PPi binding site [chemical binding]; other site
762903004918	candidate oxyanion hole; other site
762903004919	catalytic triad [active]
762903004920	potential glutamine specificity residues [chemical binding]; other site
762903004921	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
762903004922	ATP Binding subdomain [chemical binding]; other site
762903004923	Ligand Binding sites [chemical binding]; other site
762903004924	Dimerization subdomain; other site
762903004925	hypothetical protein; Provisional; Region: PRK08262
762903004926	M20 Peptidase, carboxypeptidase yscS; Region: M20_yscS; cd05674
762903004927	metal binding site [ion binding]; metal-binding site
762903004928	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
762903004929	catalytic motif [active]
762903004930	Zn binding site [ion binding]; other site
762903004931	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
762903004932	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
762903004933	Glutamine amidotransferase domain; Region: GATase_6; pfam13522
762903004934	active site
762903004935	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
762903004936	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
762903004937	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
762903004938	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
762903004939	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
762903004940	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
762903004941	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
762903004942	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
762903004943	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
762903004944	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
762903004945	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
762903004946	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
762903004947	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
762903004948	glutamate racemase; Provisional; Region: PRK00865
762903004949	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
762903004950	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
762903004951	DNA binding residues [nucleotide binding]
762903004952	dimerization interface [polypeptide binding]; other site
762903004953	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903004954	periplasmic chaperone; Provisional; Region: PRK10780
762903004955	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
762903004956	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
762903004957	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
762903004958	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
762903004959	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
762903004960	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
762903004961	Surface antigen; Region: Bac_surface_Ag; pfam01103
762903004962	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
762903004963	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
762903004964	catalytic residue [active]
762903004965	putative FPP diphosphate  binding site; other site
762903004966	putative FPP binding hydrophobic cleft; other site
762903004967	dimer interface [polypeptide binding]; other site
762903004968	putative IPP diphosphate binding site; other site
762903004969	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
762903004970	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
762903004971	FOG: CBS domain [General function prediction only]; Region: COG0517
762903004972	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
762903004973	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903004974	Yqey-like protein; Region: YqeY; pfam09424
762903004975	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
762903004976	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
762903004977	putative NAD(P) binding site [chemical binding]; other site
762903004978	homotetramer interface [polypeptide binding]; other site
762903004979	homodimer interface [polypeptide binding]; other site
762903004980	active site
762903004981	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
762903004982	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
762903004983	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
762903004984	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903004985	motif II; other site
762903004986	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
762903004987	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
762903004988	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903004989	S-adenosylmethionine binding site [chemical binding]; other site
762903004990	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
762903004991	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
762903004992	G1 box; other site
762903004993	GTP/Mg2+ binding site [chemical binding]; other site
762903004994	Switch I region; other site
762903004995	G2 box; other site
762903004996	G3 box; other site
762903004997	Switch II region; other site
762903004998	G4 box; other site
762903004999	G5 box; other site
762903005000	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
762903005001	UbiA prenyltransferase family; Region: UbiA; pfam01040
762903005002	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
762903005003	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
762903005004	active site
762903005005	Zn binding site [ion binding]; other site
762903005006	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
762903005007	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
762903005008	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
762903005009	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
762903005010	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
762903005011	ligand binding site [chemical binding]; other site
762903005012	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
762903005013	tetramer interface [polypeptide binding]; other site
762903005014	TPP-binding site [chemical binding]; other site
762903005015	heterodimer interface [polypeptide binding]; other site
762903005016	phosphorylation loop region [posttranslational modification]
762903005017	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
762903005018	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
762903005019	PYR/PP interface [polypeptide binding]; other site
762903005020	dimer interface [polypeptide binding]; other site
762903005021	TPP binding site [chemical binding]; other site
762903005022	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
762903005023	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
762903005024	aspartate aminotransferase; Provisional; Region: PRK07568
762903005025	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
762903005026	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903005027	homodimer interface [polypeptide binding]; other site
762903005028	catalytic residue [active]
762903005029	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
762903005030	ligand binding site [chemical binding]; other site
762903005031	active site
762903005032	UGI interface [polypeptide binding]; other site
762903005033	catalytic site [active]
762903005034	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
762903005035	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
762903005036	putative DNA binding site [nucleotide binding]; other site
762903005037	putative Zn2+ binding site [ion binding]; other site
762903005038	AsnC family; Region: AsnC_trans_reg; pfam01037
762903005039	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
762903005040	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
762903005041	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
762903005042	FeoA domain; Region: FeoA; pfam04023
762903005043	manganese transport protein MntH; Reviewed; Region: PRK00701
762903005044	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
762903005045	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
762903005046	Ligand Binding Site [chemical binding]; other site
762903005047	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903005048	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
762903005049	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
762903005050	N-terminal plug; other site
762903005051	ligand-binding site [chemical binding]; other site
762903005052	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
762903005053	DinB family; Region: DinB; cl17821
762903005054	DinB superfamily; Region: DinB_2; pfam12867
762903005055	Chromate resistance exported protein; Region: Chrome_Resist; pfam09828
762903005056	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903005057	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903005058	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
762903005059	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
762903005060	Chromate transporter; Region: Chromate_transp; pfam02417
762903005061	Predicted transcriptional regulator [Transcription]; Region: COG2378
762903005062	HTH domain; Region: HTH_11; pfam08279
762903005063	WYL domain; Region: WYL; pfam13280
762903005064	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
762903005065	SmpB-tmRNA interface; other site
762903005066	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
762903005067	MgtC family; Region: MgtC; pfam02308
762903005068	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
762903005069	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903005070	TIGR01777 family protein; Region: yfcH
762903005071	NAD(P) binding site [chemical binding]; other site
762903005072	active site
762903005073	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
762903005074	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
762903005075	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
762903005076	proposed catalytic triad [active]
762903005077	active site nucleophile [active]
762903005078	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
762903005079	proposed catalytic triad [active]
762903005080	active site nucleophile [active]
762903005081	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903005082	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903005083	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903005084	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903005085	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
762903005086	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903005087	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
762903005088	K+ potassium transporter; Region: K_trans; pfam02705
762903005089	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
762903005090	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
762903005091	Peptidase family M23; Region: Peptidase_M23; pfam01551
762903005092	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
762903005093	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
762903005094	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
762903005095	catalytic triad [active]
762903005096	Putative esterase; Region: Esterase; pfam00756
762903005097	S-formylglutathione hydrolase; Region: PLN02442
762903005098	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
762903005099	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
762903005100	nucleotide binding site [chemical binding]; other site
762903005101	NEF interaction site [polypeptide binding]; other site
762903005102	SBD interface [polypeptide binding]; other site
762903005103	acyl-coenzyme A oxidase; Region: PLN02526
762903005104	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
762903005105	active site
762903005106	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903005107	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903005108	bacillithiol biosynthesis deacetylase BshB1; Region: thiol_BshB1; TIGR04001
762903005109	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
762903005110	catalytic residues [active]
762903005111	dimer interface [polypeptide binding]; other site
762903005112	Domain of unknown function (DUF4294); Region: DUF4294; pfam14127
762903005113	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
762903005114	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
762903005115	Zn2+ binding site [ion binding]; other site
762903005116	Mg2+ binding site [ion binding]; other site
762903005117	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
762903005118	synthetase active site [active]
762903005119	NTP binding site [chemical binding]; other site
762903005120	metal binding site [ion binding]; metal-binding site
762903005121	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
762903005122	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
762903005123	ferric uptake regulator; Provisional; Region: fur; PRK09462
762903005124	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
762903005125	metal binding site 2 [ion binding]; metal-binding site
762903005126	putative DNA binding helix; other site
762903005127	metal binding site 1 [ion binding]; metal-binding site
762903005128	dimer interface [polypeptide binding]; other site
762903005129	structural Zn2+ binding site [ion binding]; other site
762903005130	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
762903005131	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
762903005132	GDP-binding site [chemical binding]; other site
762903005133	ACT binding site; other site
762903005134	IMP binding site; other site
762903005135	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
762903005136	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
762903005137	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903005138	NHL repeat; Region: NHL; pfam01436
762903005139	NHL repeat; Region: NHL; pfam01436
762903005140	NHL repeat; Region: NHL; pfam01436
762903005141	Cadherin tandem repeat domain; Region: Cadherin_repeat; cd11304
762903005142	Ca2+ binding site [ion binding]; other site
762903005143	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903005144	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903005145	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903005146	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903005147	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903005148	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903005149	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
762903005150	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
762903005151	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
762903005152	active site clefts [active]
762903005153	zinc binding site [ion binding]; other site
762903005154	dimer interface [polypeptide binding]; other site
762903005155	Peptidase family M48; Region: Peptidase_M48; pfam01435
762903005156	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
762903005157	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
762903005158	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
762903005159	dimerization interface [polypeptide binding]; other site
762903005160	active site
762903005161	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
762903005162	phosphoglyceromutase; Provisional; Region: PRK05434
762903005163	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
762903005164	metal binding site 2 [ion binding]; metal-binding site
762903005165	putative DNA binding helix; other site
762903005166	metal binding site 1 [ion binding]; metal-binding site
762903005167	dimer interface [polypeptide binding]; other site
762903005168	structural Zn2+ binding site [ion binding]; other site
762903005169	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
762903005170	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
762903005171	Soluble P-type ATPase [General function prediction only]; Region: COG4087
762903005172	DinB superfamily; Region: DinB_2; pfam12867
762903005173	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903005174	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903005175	ligand binding site [chemical binding]; other site
762903005176	flexible hinge region; other site
762903005177	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14609
762903005178	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
762903005179	thymidylate synthase; Reviewed; Region: thyA; PRK01827
762903005180	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
762903005181	dimerization interface [polypeptide binding]; other site
762903005182	active site
762903005183	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
762903005184	four helix bundle protein; Region: TIGR02436
762903005185	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
762903005186	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
762903005187	folate binding site [chemical binding]; other site
762903005188	NADP+ binding site [chemical binding]; other site
762903005189	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
762903005190	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
762903005191	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
762903005192	Protein export membrane protein; Region: SecD_SecF; pfam02355
762903005193	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
762903005194	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
762903005195	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
762903005196	active site
762903005197	catalytic triad [active]
762903005198	oxyanion hole [active]
762903005199	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
762903005200	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
762903005201	active site
762903005202	intersubunit interface [polypeptide binding]; other site
762903005203	zinc binding site [ion binding]; other site
762903005204	Na+ binding site [ion binding]; other site
762903005205	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
762903005206	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
762903005207	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
762903005208	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
762903005209	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
762903005210	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
762903005211	Right handed beta helix region; Region: Beta_helix; pfam13229
762903005212	Right handed beta helix region; Region: Beta_helix; pfam13229
762903005213	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
762903005214	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
762903005215	protein binding site [polypeptide binding]; other site
762903005216	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903005217	Sulfatase; Region: Sulfatase; pfam00884
762903005218	Protein of unknown function (DUF1310); Region: DUF1310; pfam07006
762903005219	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
762903005220	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
762903005221	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
762903005222	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
762903005223	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903005224	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903005225	Alpha-L-fucosidase; Region: Alpha_L_fucos; pfam01120
762903005226	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
762903005227	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903005228	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903005229	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903005230	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903005231	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903005232	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903005233	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903005234	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
762903005235	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
762903005236	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
762903005237	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
762903005238	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
762903005239	Cupin domain; Region: Cupin_2; cl17218
762903005240	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903005241	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903005242	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903005243	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903005244	Domain of unknown function (DUF718); Region: DUF718; pfam05336
762903005245	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
762903005246	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
762903005247	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
762903005248	catalytic residue [active]
762903005249	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
762903005250	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903005251	S-adenosylmethionine binding site [chemical binding]; other site
762903005252	PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_4; cd03395
762903005253	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
762903005254	active site
762903005255	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
762903005256	ZIP Zinc transporter; Region: Zip; pfam02535
762903005257	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
762903005258	MarR family; Region: MarR_2; pfam12802
762903005259	putative exonuclease, DNA ligase-associated; Region: Xnuc_lig_assoc; TIGR04122
762903005260	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
762903005261	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
762903005262	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
762903005263	CoA-binding site [chemical binding]; other site
762903005264	Preprotein translocase subunit; Region: YajC; pfam02699
762903005265	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
762903005266	transcription antitermination factor NusB; Region: nusB; TIGR01951
762903005267	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
762903005268	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; pfam00208
762903005269	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
762903005270	NAD binding site [chemical binding]; other site
762903005271	Phe binding site; other site
762903005272	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
762903005273	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
762903005274	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903005275	Walker A/P-loop; other site
762903005276	ATP binding site [chemical binding]; other site
762903005277	Q-loop/lid; other site
762903005278	ABC transporter signature motif; other site
762903005279	Walker B; other site
762903005280	D-loop; other site
762903005281	H-loop/switch region; other site
762903005282	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
762903005283	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
762903005284	DNA-binding site [nucleotide binding]; DNA binding site
762903005285	RNA-binding motif; other site
762903005286	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977
762903005287	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
762903005288	Protein of unknown function (DUF1211); Region: DUF1211; cl01421
762903005289	GTP-binding protein YchF; Reviewed; Region: PRK09601
762903005290	YchF GTPase; Region: YchF; cd01900
762903005291	G1 box; other site
762903005292	GTP/Mg2+ binding site [chemical binding]; other site
762903005293	Switch I region; other site
762903005294	G2 box; other site
762903005295	Switch II region; other site
762903005296	G3 box; other site
762903005297	G4 box; other site
762903005298	G5 box; other site
762903005299	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
762903005300	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
762903005301	hydrophobic ligand binding site; other site
762903005302	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
762903005303	dimer interface [polypeptide binding]; other site
762903005304	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
762903005305	dimer interface [polypeptide binding]; other site
762903005306	Protein of unknown function DUF72; Region: DUF72; pfam01904
762903005307	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
762903005308	catalytic residues [active]
762903005309	dimer interface [polypeptide binding]; other site
762903005310	PspC domain; Region: PspC; cl00864
762903005311	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
762903005312	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
762903005313	active site
762903005314	dimer interface [polypeptide binding]; other site
762903005315	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
762903005316	Transcription termination factor [Transcription]; Region: Rho; COG1158
762903005317	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
762903005318	RNA binding site [nucleotide binding]; other site
762903005319	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
762903005320	multimer interface [polypeptide binding]; other site
762903005321	Walker A motif; other site
762903005322	ATP binding site [chemical binding]; other site
762903005323	Walker B motif; other site
762903005324	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
762903005325	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
762903005326	FOG: HPt domain [Signal transduction mechanisms]; Region: ArcB; COG2198
762903005327	active site
762903005328	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
762903005329	catalytic center binding site [active]
762903005330	ATP binding site [chemical binding]; other site
762903005331	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
762903005332	tandem repeat interface [polypeptide binding]; other site
762903005333	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
762903005334	oligomer interface [polypeptide binding]; other site
762903005335	active site residues [active]
762903005336	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
762903005337	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
762903005338	tandem repeat interface [polypeptide binding]; other site
762903005339	oligomer interface [polypeptide binding]; other site
762903005340	active site residues [active]
762903005341	hypothetical protein; Provisional; Region: PRK08609
762903005342	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
762903005343	metal binding triad [ion binding]; metal-binding site
762903005344	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
762903005345	active site
762903005346	Protein of unknown function (DUF4254); Region: DUF4254; pfam14063
762903005347	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
762903005348	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
762903005349	putative active site [active]
762903005350	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
762903005351	catalytic core [active]
762903005352	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
762903005353	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
762903005354	homodimer interface [polypeptide binding]; other site
762903005355	metal binding site [ion binding]; metal-binding site
762903005356	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
762903005357	homodimer interface [polypeptide binding]; other site
762903005358	active site
762903005359	putative chemical substrate binding site [chemical binding]; other site
762903005360	metal binding site [ion binding]; metal-binding site
762903005361	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
762903005362	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903005363	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903005364	DNA binding residues [nucleotide binding]
762903005365	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
762903005366	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
762903005367	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
762903005368	FtsX-like permease family; Region: FtsX; pfam02687
762903005369	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
762903005370	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
762903005371	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
762903005372	putative active site [active]
762903005373	substrate binding site [chemical binding]; other site
762903005374	putative cosubstrate binding site; other site
762903005375	catalytic site [active]
762903005376	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
762903005377	substrate binding site [chemical binding]; other site
762903005378	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
762903005379	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
762903005380	homodimer interface [polypeptide binding]; other site
762903005381	substrate-cofactor binding pocket; other site
762903005382	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903005383	catalytic residue [active]
762903005384	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
762903005385	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
762903005386	RNA binding surface [nucleotide binding]; other site
762903005387	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
762903005388	active site
762903005389	1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515
762903005390	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
762903005391	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
762903005392	catalytic residue [active]
762903005393	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
762903005394	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
762903005395	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
762903005396	alphaNTD homodimer interface [polypeptide binding]; other site
762903005397	alphaNTD - beta interaction site [polypeptide binding]; other site
762903005398	alphaNTD - beta' interaction site [polypeptide binding]; other site
762903005399	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
762903005400	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
762903005401	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
762903005402	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
762903005403	RNA binding surface [nucleotide binding]; other site
762903005404	30S ribosomal protein S11; Validated; Region: PRK05309
762903005405	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
762903005406	30S ribosomal protein S13; Region: bact_S13; TIGR03631
762903005407	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
762903005408	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
762903005409	rRNA binding site [nucleotide binding]; other site
762903005410	predicted 30S ribosome binding site; other site
762903005411	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
762903005412	active site
762903005413	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
762903005414	SecY translocase; Region: SecY; pfam00344
762903005415	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
762903005416	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
762903005417	23S rRNA binding site [nucleotide binding]; other site
762903005418	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
762903005419	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
762903005420	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
762903005421	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
762903005422	23S rRNA interface [nucleotide binding]; other site
762903005423	5S rRNA interface [nucleotide binding]; other site
762903005424	L27 interface [polypeptide binding]; other site
762903005425	L5 interface [polypeptide binding]; other site
762903005426	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
762903005427	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
762903005428	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
762903005429	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
762903005430	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
762903005431	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
762903005432	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
762903005433	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
762903005434	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
762903005435	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
762903005436	RNA binding site [nucleotide binding]; other site
762903005437	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
762903005438	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
762903005439	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
762903005440	23S rRNA interface [nucleotide binding]; other site
762903005441	putative translocon interaction site; other site
762903005442	signal recognition particle (SRP54) interaction site; other site
762903005443	L23 interface [polypeptide binding]; other site
762903005444	trigger factor interaction site; other site
762903005445	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
762903005446	23S rRNA interface [nucleotide binding]; other site
762903005447	5S rRNA interface [nucleotide binding]; other site
762903005448	putative antibiotic binding site [chemical binding]; other site
762903005449	L25 interface [polypeptide binding]; other site
762903005450	L27 interface [polypeptide binding]; other site
762903005451	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
762903005452	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
762903005453	G-X-X-G motif; other site
762903005454	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
762903005455	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
762903005456	putative translocon binding site; other site
762903005457	protein-rRNA interface [nucleotide binding]; other site
762903005458	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
762903005459	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
762903005460	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
762903005461	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
762903005462	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
762903005463	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
762903005464	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
762903005465	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
762903005466	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
762903005467	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
762903005468	elongation factor G; Reviewed; Region: PRK12739
762903005469	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
762903005470	G1 box; other site
762903005471	putative GEF interaction site [polypeptide binding]; other site
762903005472	GTP/Mg2+ binding site [chemical binding]; other site
762903005473	Switch I region; other site
762903005474	G2 box; other site
762903005475	G3 box; other site
762903005476	Switch II region; other site
762903005477	G4 box; other site
762903005478	G5 box; other site
762903005479	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
762903005480	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
762903005481	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
762903005482	30S ribosomal protein S7; Validated; Region: PRK05302
762903005483	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
762903005484	S17 interaction site [polypeptide binding]; other site
762903005485	S8 interaction site; other site
762903005486	16S rRNA interaction site [nucleotide binding]; other site
762903005487	streptomycin interaction site [chemical binding]; other site
762903005488	23S rRNA interaction site [nucleotide binding]; other site
762903005489	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
762903005490	Transcriptional regulator [Transcription]; Region: LysR; COG0583
762903005491	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
762903005492	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
762903005493	dimerization interface [polypeptide binding]; other site
762903005494	substrate binding pocket [chemical binding]; other site
762903005495	Methyltransferase domain; Region: Methyltransf_31; pfam13847
762903005496	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903005497	S-adenosylmethionine binding site [chemical binding]; other site
762903005498	glutamate dehydrogenase; Provisional; Region: PRK09414
762903005499	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
762903005500	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
762903005501	NAD(P) binding site [chemical binding]; other site
762903005502	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
762903005503	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
762903005504	active site
762903005505	substrate binding site [chemical binding]; other site
762903005506	cosubstrate binding site; other site
762903005507	catalytic site [active]
762903005508	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
762903005509	tetramer interface [polypeptide binding]; other site
762903005510	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
762903005511	active site
762903005512	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
762903005513	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
762903005514	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
762903005515	putative active site [active]
762903005516	putative substrate binding site [chemical binding]; other site
762903005517	putative cosubstrate binding site; other site
762903005518	catalytic site [active]
762903005519	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
762903005520	methionine sulfoxide reductase A; Provisional; Region: PRK14054
762903005521	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
762903005522	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903005523	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
762903005524	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
762903005525	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
762903005526	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
762903005527	Putative glucoamylase; Region: Glycoamylase; pfam10091
762903005528	Bacterial Ig-like domain; Region: Big_5; pfam13205
762903005529	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
762903005530	Putative glucoamylase; Region: Glycoamylase; pfam10091
762903005531	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
762903005532	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903005533	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903005534	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903005535	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903005536	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903005537	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903005538	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903005539	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
762903005540	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
762903005541	CAP-like domain; other site
762903005542	active site
762903005543	primary dimer interface [polypeptide binding]; other site
762903005544	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
762903005545	four helix bundle protein; Region: TIGR02436
762903005546	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
762903005547	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903005548	ATP binding site [chemical binding]; other site
762903005549	Mg2+ binding site [ion binding]; other site
762903005550	G-X-G motif; other site
762903005551	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second...; Region: TopoII_MutL_Trans; cl02783
762903005552	ATP binding site [chemical binding]; other site
762903005553	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
762903005554	active site
762903005555	metal binding site [ion binding]; metal-binding site
762903005556	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
762903005557	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
762903005558	active site
762903005559	Domain of unknown function (DUF4403); Region: DUF4403; pfam14356
762903005560	2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD; TIGR01832
762903005561	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
762903005562	NADP binding site [chemical binding]; other site
762903005563	homodimer interface [polypeptide binding]; other site
762903005564	active site
762903005565	putative transporter; Provisional; Region: PRK10484
762903005566	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
762903005567	Na binding site [ion binding]; other site
762903005568	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903005569	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903005570	Domain of unknown function (DUF718); Region: DUF718; cl01281
762903005571	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
762903005572	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903005573	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903005574	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903005575	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
762903005576	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
762903005577	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
762903005578	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
762903005579	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
762903005580	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903005581	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
762903005582	dimer interface [polypeptide binding]; other site
762903005583	phosphorylation site [posttranslational modification]
762903005584	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903005585	ATP binding site [chemical binding]; other site
762903005586	Mg2+ binding site [ion binding]; other site
762903005587	G-X-G motif; other site
762903005588	TPR repeat; Region: TPR_11; pfam13414
762903005589	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903005590	TPR motif; other site
762903005591	binding surface
762903005592	Tetratricopeptide repeat; Region: TPR_16; pfam13432
762903005593	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903005594	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903005595	active site
762903005596	phosphorylation site [posttranslational modification]
762903005597	intermolecular recognition site; other site
762903005598	dimerization interface [polypeptide binding]; other site
762903005599	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
762903005600	DNA binding site [nucleotide binding]
762903005601	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903005602	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
762903005603	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903005604	dimer interface [polypeptide binding]; other site
762903005605	phosphorylation site [posttranslational modification]
762903005606	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903005607	ATP binding site [chemical binding]; other site
762903005608	Mg2+ binding site [ion binding]; other site
762903005609	G-X-G motif; other site
762903005610	Sulfatase; Region: Sulfatase; pfam00884
762903005611	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
762903005612	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903005613	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903005614	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903005615	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903005616	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903005617	D-galactonate transporter; Region: 2A0114; TIGR00893
762903005618	putative substrate translocation pore; other site
762903005619	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903005620	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903005621	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903005622	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
762903005623	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
762903005624	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cl00541
762903005625	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
762903005626	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
762903005627	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903005628	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
762903005629	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903005630	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903005631	SusD family; Region: SusD; pfam07980
762903005632	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903005633	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903005634	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903005635	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903005636	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903005637	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903005638	DNA binding site [nucleotide binding]
762903005639	domain linker motif; other site
762903005640	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903005641	dimerization interface [polypeptide binding]; other site
762903005642	ligand binding site [chemical binding]; other site
762903005643	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903005644	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
762903005645	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
762903005646	Sulfate transporter family; Region: Sulfate_transp; pfam00916
762903005647	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
762903005648	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
762903005649	Transcriptional regulators [Transcription]; Region: MarR; COG1846
762903005650	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
762903005651	active site
762903005652	homotetramer interface [polypeptide binding]; other site
762903005653	phytoene desaturase; Region: crtI_fam; TIGR02734
762903005654	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
762903005655	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
762903005656	active site lid residues [active]
762903005657	substrate binding pocket [chemical binding]; other site
762903005658	catalytic residues [active]
762903005659	substrate-Mg2+ binding site; other site
762903005660	aspartate-rich region 1; other site
762903005661	aspartate-rich region 2; other site
762903005662	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
762903005663	putative hydrophobic ligand binding site [chemical binding]; other site
762903005664	beta-carotene hydroxylase; Region: PLN02601
762903005665	lycopene cyclase domain; Region: CarR_dom_SF; TIGR03462
762903005666	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
762903005667	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
762903005668	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
762903005669	Zn2+ binding site [ion binding]; other site
762903005670	Mg2+ binding site [ion binding]; other site
762903005671	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903005672	putative substrate translocation pore; other site
762903005673	POT family; Region: PTR2; cl17359
762903005674	POT family; Region: PTR2; cl17359
762903005675	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
762903005676	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903005677	putative substrate translocation pore; other site
762903005678	POT family; Region: PTR2; cl17359
762903005679	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
762903005680	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903005681	Ligand binding site; other site
762903005682	Putative Catalytic site; other site
762903005683	DXD motif; other site
762903005684	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
762903005685	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903005686	Walker A motif; other site
762903005687	ATP binding site [chemical binding]; other site
762903005688	Walker B motif; other site
762903005689	arginine finger; other site
762903005690	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
762903005691	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
762903005692	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
762903005693	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional; Region: PRK02048
762903005694	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
762903005695	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
762903005696	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
762903005697	Coenzyme A binding pocket [chemical binding]; other site
762903005698	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
762903005699	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
762903005700	DNA binding residues [nucleotide binding]
762903005701	dimerization interface [polypeptide binding]; other site
762903005702	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903005703	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903005704	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
762903005705	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
762903005706	PspC domain; Region: PspC; pfam04024
762903005707	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
762903005708	classical (c) SDRs; Region: SDR_c; cd05233
762903005709	NAD(P) binding site [chemical binding]; other site
762903005710	active site
762903005711	Permease; Region: Permease; pfam02405
762903005712	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
762903005713	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
762903005714	Walker A/P-loop; other site
762903005715	ATP binding site [chemical binding]; other site
762903005716	Q-loop/lid; other site
762903005717	ABC transporter signature motif; other site
762903005718	Walker B; other site
762903005719	D-loop; other site
762903005720	H-loop/switch region; other site
762903005721	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
762903005722	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903005723	S-adenosylmethionine binding site [chemical binding]; other site
762903005724	Domain of unknown function (DUF202); Region: DUF202; pfam02656
762903005725	Surface antigen; Region: Bac_surface_Ag; pfam01103
762903005726	Family of unknown function (DUF490); Region: DUF490; pfam04357
762903005727	Family of unknown function (DUF490); Region: DUF490; pfam04357
762903005728	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
762903005729	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903005730	catalytic residues [active]
762903005731	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903005732	Major Facilitator Superfamily; Region: MFS_1; pfam07690
762903005733	putative substrate translocation pore; other site
762903005734	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
762903005735	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
762903005736	nucleoside/Zn binding site; other site
762903005737	dimer interface [polypeptide binding]; other site
762903005738	catalytic motif [active]
762903005739	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
762903005740	RNA binding surface [nucleotide binding]; other site
762903005741	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
762903005742	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
762903005743	trimer interface [polypeptide binding]; other site
762903005744	active site
762903005745	substrate binding site [chemical binding]; other site
762903005746	CoA binding site [chemical binding]; other site
762903005747	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903005748	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
762903005749	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
762903005750	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
762903005751	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
762903005752	active site
762903005753	NTP binding site [chemical binding]; other site
762903005754	metal binding triad [ion binding]; metal-binding site
762903005755	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
762903005756	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
762903005757	Zn2+ binding site [ion binding]; other site
762903005758	Mg2+ binding site [ion binding]; other site
762903005759	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
762903005760	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
762903005761	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
762903005762	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
762903005763	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
762903005764	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
762903005765	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
762903005766	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
762903005767	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
762903005768	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
762903005769	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
762903005770	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
762903005771	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
762903005772	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
762903005773	DNA binding site [nucleotide binding]
762903005774	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
762903005775	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
762903005776	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
762903005777	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
762903005778	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
762903005779	RPB11 interaction site [polypeptide binding]; other site
762903005780	RPB12 interaction site [polypeptide binding]; other site
762903005781	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
762903005782	RPB3 interaction site [polypeptide binding]; other site
762903005783	RPB1 interaction site [polypeptide binding]; other site
762903005784	RPB11 interaction site [polypeptide binding]; other site
762903005785	RPB10 interaction site [polypeptide binding]; other site
762903005786	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
762903005787	core dimer interface [polypeptide binding]; other site
762903005788	peripheral dimer interface [polypeptide binding]; other site
762903005789	L10 interface [polypeptide binding]; other site
762903005790	L11 interface [polypeptide binding]; other site
762903005791	putative EF-Tu interaction site [polypeptide binding]; other site
762903005792	putative EF-G interaction site [polypeptide binding]; other site
762903005793	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
762903005794	23S rRNA interface [nucleotide binding]; other site
762903005795	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
762903005796	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
762903005797	mRNA/rRNA interface [nucleotide binding]; other site
762903005798	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
762903005799	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
762903005800	23S rRNA interface [nucleotide binding]; other site
762903005801	L7/L12 interface [polypeptide binding]; other site
762903005802	putative thiostrepton binding site; other site
762903005803	L25 interface [polypeptide binding]; other site
762903005804	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
762903005805	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
762903005806	putative homodimer interface [polypeptide binding]; other site
762903005807	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
762903005808	heterodimer interface [polypeptide binding]; other site
762903005809	homodimer interface [polypeptide binding]; other site
762903005810	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
762903005811	elongation factor Tu; Reviewed; Region: PRK12735
762903005812	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
762903005813	G1 box; other site
762903005814	GEF interaction site [polypeptide binding]; other site
762903005815	GTP/Mg2+ binding site [chemical binding]; other site
762903005816	Switch I region; other site
762903005817	G2 box; other site
762903005818	G3 box; other site
762903005819	Switch II region; other site
762903005820	G4 box; other site
762903005821	G5 box; other site
762903005822	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
762903005823	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
762903005824	Antibiotic Binding Site [chemical binding]; other site
762903005825	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
762903005826	30S subunit binding site; other site
762903005827	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
762903005828	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
762903005829	active site
762903005830	DNA binding site [nucleotide binding]
762903005831	Int/Topo IB signature motif; other site
762903005832	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
762903005833	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
762903005834	active site
762903005835	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
762903005836	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
762903005837	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
762903005838	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
762903005839	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
762903005840	putative acyl-acceptor binding pocket; other site
762903005841	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
762903005842	Fatty acid desaturase; Region: FA_desaturase_2; pfam03405
762903005843	Acyl ACP desaturase, ferritin-like diiron-binding domain; Region: Acyl_ACP_Desat; cd01050
762903005844	homodimer interface [polypeptide binding]; other site
762903005845	putative substrate binding pocket [chemical binding]; other site
762903005846	diiron center [ion binding]; other site
762903005847	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903005848	PhoPQ-activated pathogenicity-related protein; Region: PhoPQ_related; cl01750
762903005849	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
762903005850	Secretin and TonB N terminus short domain; Region: STN; pfam07660
762903005851	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903005852	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903005853	FecR protein; Region: FecR; pfam04773
762903005854	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903005855	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903005856	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903005857	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903005858	DNA binding residues [nucleotide binding]
762903005859	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
762903005860	4Fe-4S binding domain; Region: Fer4_3; pfam12798
762903005861	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
762903005862	Cysteine-rich domain; Region: CCG; pfam02754
762903005863	Cysteine-rich domain; Region: CCG; pfam02754
762903005864	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
762903005865	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
762903005866	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
762903005867	Transglycosylase; Region: Transgly; cl17702
762903005868	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
762903005869	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
762903005870	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
762903005871	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
762903005872	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
762903005873	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14971
762903005874	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903005875	Walker A motif; other site
762903005876	ATP binding site [chemical binding]; other site
762903005877	Walker B motif; other site
762903005878	arginine finger; other site
762903005879	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
762903005880	Uncharacterized conserved protein (DUF2196); Region: DUF2196; pfam09962
762903005881	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
762903005882	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
762903005883	ligand binding site [chemical binding]; other site
762903005884	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY; Region: NGN_SP_UpxY; cd09895
762903005885	transcriptional activator RfaH; Region: RfaH; TIGR01955
762903005886	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
762903005887	heterodimer interface [polypeptide binding]; other site
762903005888	homodimer interface [polypeptide binding]; other site
762903005889	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
762903005890	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
762903005891	Mg++ binding site [ion binding]; other site
762903005892	putative catalytic motif [active]
762903005893	substrate binding site [chemical binding]; other site
762903005894	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
762903005895	metal-binding site
762903005896	long tail fiber, proximal subunit; Provisional; Region: 34; PHA02584
762903005897	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
762903005898	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
762903005899	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
762903005900	exopolysaccharide/PEP-CTERM locus tyrosine autokinase; Region: pepcterm_TyrKin; TIGR03018
762903005901	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
762903005902	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903005903	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
762903005904	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
762903005905	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
762903005906	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
762903005907	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
762903005908	putative active site [active]
762903005909	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
762903005910	four helix bundle protein; Region: TIGR02436
762903005911	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
762903005912	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
762903005913	Walker A/P-loop; other site
762903005914	ATP binding site [chemical binding]; other site
762903005915	Q-loop/lid; other site
762903005916	ABC transporter signature motif; other site
762903005917	Walker B; other site
762903005918	D-loop; other site
762903005919	H-loop/switch region; other site
762903005920	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
762903005921	putative carbohydrate binding site [chemical binding]; other site
762903005922	Methyltransferase domain; Region: Methyltransf_23; pfam13489
762903005923	Methyltransferase domain; Region: Methyltransf_12; pfam08242
762903005924	S-adenosylmethionine binding site [chemical binding]; other site
762903005925	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
762903005926	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
762903005927	active site
762903005928	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
762903005929	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
762903005930	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
762903005931	metal-binding site
762903005932	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
762903005933	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
762903005934	metal-binding site
762903005935	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903005936	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903005937	active site
762903005938	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
762903005939	metal-binding site
762903005940	Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases; Region: Glyco_tran_WbsX; cd11579
762903005941	putative ligand binding site [chemical binding]; other site
762903005942	putative catalytic site [active]
762903005943	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
762903005944	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
762903005945	Probable Catalytic site; other site
762903005946	metal-binding site
762903005947	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
762903005948	active site
762903005949	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
762903005950	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
762903005951	trimer interface [polypeptide binding]; other site
762903005952	active site
762903005953	substrate binding site [chemical binding]; other site
762903005954	CoA binding site [chemical binding]; other site
762903005955	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
762903005956	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903005957	active site
762903005958	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
762903005959	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903005960	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
762903005961	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903005962	active site
762903005963	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
762903005964	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903005965	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
762903005966	oligomeric interface; other site
762903005967	putative active site [active]
762903005968	homodimer interface [polypeptide binding]; other site
762903005969	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
762903005970	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
762903005971	putative metal binding site; other site
762903005972	exosortase/archaeosortase family protein; Region: exo_archaeo; TIGR04178
762903005973	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
762903005974	GIY-YIG motif/motif A; other site
762903005975	putative active site [active]
762903005976	putative metal binding site [ion binding]; other site
762903005977	putative acyl transferase; Provisional; Region: PRK10502
762903005978	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
762903005979	putative trimer interface [polypeptide binding]; other site
762903005980	putative active site [active]
762903005981	putative substrate binding site [chemical binding]; other site
762903005982	putative CoA binding site [chemical binding]; other site
762903005983	GTPase CgtA; Reviewed; Region: obgE; PRK12299
762903005984	GTP1/OBG; Region: GTP1_OBG; pfam01018
762903005985	Obg GTPase; Region: Obg; cd01898
762903005986	G1 box; other site
762903005987	GTP/Mg2+ binding site [chemical binding]; other site
762903005988	Switch I region; other site
762903005989	G2 box; other site
762903005990	G3 box; other site
762903005991	Switch II region; other site
762903005992	G4 box; other site
762903005993	G5 box; other site
762903005994	adenylate kinase; Reviewed; Region: adk; PRK00279
762903005995	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
762903005996	AMP-binding site [chemical binding]; other site
762903005997	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
762903005998	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
762903005999	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
762903006000	hypothetical protein; Provisional; Region: PRK13665
762903006001	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
762903006002	Peroxiredoxin (PRX) family, AhpE-like subfamily; composed of proteins similar to Mycobacterium tuberculosis AhpE. AhpE is described as a 1-cys PRX because of the absence of a resolving cysteine. The structure and sequence of AhpE, however, show greater...; Region: PRX_AhpE_like; cd03018
762903006003	dimer interface [polypeptide binding]; other site
762903006004	catalytic triad [active]
762903006005	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
762903006006	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
762903006007	NADP binding site [chemical binding]; other site
762903006008	active site
762903006009	putative substrate binding site [chemical binding]; other site
762903006010	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
762903006011	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
762903006012	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
762903006013	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
762903006014	alpha subunit interaction interface [polypeptide binding]; other site
762903006015	Walker A motif; other site
762903006016	ATP binding site [chemical binding]; other site
762903006017	Walker B motif; other site
762903006018	inhibitor binding site; inhibition site
762903006019	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
762903006020	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
762903006021	gamma subunit interface [polypeptide binding]; other site
762903006022	epsilon subunit interface [polypeptide binding]; other site
762903006023	LBP interface [polypeptide binding]; other site
762903006024	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
762903006025	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
762903006026	homodimer interface [polypeptide binding]; other site
762903006027	substrate-cofactor binding pocket; other site
762903006028	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903006029	catalytic residue [active]
762903006030	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
762903006031	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
762903006032	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
762903006033	PYR/PP interface [polypeptide binding]; other site
762903006034	dimer interface [polypeptide binding]; other site
762903006035	TPP binding site [chemical binding]; other site
762903006036	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
762903006037	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
762903006038	TPP-binding site [chemical binding]; other site
762903006039	dimer interface [polypeptide binding]; other site
762903006040	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
762903006041	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
762903006042	putative valine binding site [chemical binding]; other site
762903006043	dimer interface [polypeptide binding]; other site
762903006044	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
762903006045	DinB superfamily; Region: DinB_2; pfam12867
762903006046	ketol-acid reductoisomerase; Validated; Region: PRK05225
762903006047	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
762903006048	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
762903006049	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
762903006050	ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; Region: ArtP; COG4161
762903006051	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903006052	Walker A/P-loop; other site
762903006053	ATP binding site [chemical binding]; other site
762903006054	Q-loop/lid; other site
762903006055	ABC transporter signature motif; other site
762903006056	Walker B; other site
762903006057	D-loop; other site
762903006058	H-loop/switch region; other site
762903006059	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism]; Region: ModF; COG1119
762903006060	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903006061	Walker A/P-loop; other site
762903006062	ATP binding site [chemical binding]; other site
762903006063	Q-loop/lid; other site
762903006064	ABC transporter signature motif; other site
762903006065	Walker B; other site
762903006066	D-loop; other site
762903006067	H-loop/switch region; other site
762903006068	2-isopropylmalate synthase; Validated; Region: PRK00915
762903006069	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
762903006070	active site
762903006071	catalytic residues [active]
762903006072	metal binding site [ion binding]; metal-binding site
762903006073	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
762903006074	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
762903006075	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
762903006076	substrate binding site [chemical binding]; other site
762903006077	ligand binding site [chemical binding]; other site
762903006078	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
762903006079	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
762903006080	substrate binding site [chemical binding]; other site
762903006081	(R)-citramalate synthase; Provisional; Region: PRK09389
762903006082	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
762903006083	active site
762903006084	catalytic residues [active]
762903006085	metal binding site [ion binding]; metal-binding site
762903006086	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; cl07212
762903006087	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
762903006088	tartrate dehydrogenase; Region: TTC; TIGR02089
762903006089	threonine dehydratase; Validated; Region: PRK08639
762903006090	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
762903006091	tetramer interface [polypeptide binding]; other site
762903006092	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903006093	catalytic residue [active]
762903006094	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
762903006095	putative Ile/Val binding site [chemical binding]; other site
762903006096	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
762903006097	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903006098	Walker A/P-loop; other site
762903006099	ATP binding site [chemical binding]; other site
762903006100	Q-loop/lid; other site
762903006101	ABC transporter signature motif; other site
762903006102	Walker B; other site
762903006103	D-loop; other site
762903006104	H-loop/switch region; other site
762903006105	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
762903006106	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
762903006107	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903006108	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903006109	DNA binding residues [nucleotide binding]
762903006110	GH3 auxin-responsive promoter; Region: GH3; pfam03321
762903006111	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
762903006112	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
762903006113	Walker A/P-loop; other site
762903006114	ATP binding site [chemical binding]; other site
762903006115	Q-loop/lid; other site
762903006116	ABC transporter signature motif; other site
762903006117	Walker B; other site
762903006118	D-loop; other site
762903006119	H-loop/switch region; other site
762903006120	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
762903006121	DHH family; Region: DHH; pfam01368
762903006122	DHHA1 domain; Region: DHHA1; pfam02272
762903006123	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
762903006124	Response regulator receiver domain; Region: Response_reg; pfam00072
762903006125	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006126	active site
762903006127	phosphorylation site [posttranslational modification]
762903006128	intermolecular recognition site; other site
762903006129	dimerization interface [polypeptide binding]; other site
762903006130	NMT1/THI5 like; Region: NMT1; pfam09084
762903006131	YceI-like domain; Region: YceI; pfam04264
762903006132	NMT1/THI5 like; Region: NMT1; pfam09084
762903006133	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903006134	PAS fold; Region: PAS_3; pfam08447
762903006135	putative active site [active]
762903006136	heme pocket [chemical binding]; other site
762903006137	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903006138	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006139	ATP binding site [chemical binding]; other site
762903006140	Mg2+ binding site [ion binding]; other site
762903006141	G-X-G motif; other site
762903006142	glycine dehydrogenase; Provisional; Region: PRK05367
762903006143	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
762903006144	tetramer interface [polypeptide binding]; other site
762903006145	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903006146	catalytic residue [active]
762903006147	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
762903006148	tetramer interface [polypeptide binding]; other site
762903006149	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903006150	catalytic residue [active]
762903006151	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
762903006152	active site
762903006153	hydrophilic channel; other site
762903006154	dimerization interface [polypeptide binding]; other site
762903006155	catalytic residues [active]
762903006156	active site lid [active]
762903006157	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
762903006158	E3 interaction surface; other site
762903006159	lipoyl attachment site [posttranslational modification]; other site
762903006160	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
762903006161	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
762903006162	E3 interaction surface; other site
762903006163	lipoyl attachment site [posttranslational modification]; other site
762903006164	e3 binding domain; Region: E3_binding; pfam02817
762903006165	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
762903006166	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
762903006167	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
762903006168	TPP-binding site [chemical binding]; other site
762903006169	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
762903006170	PYR/PP interface [polypeptide binding]; other site
762903006171	dimer interface [polypeptide binding]; other site
762903006172	TPP binding site [chemical binding]; other site
762903006173	cryptochrome, DASH family; Region: crypto_DASH; TIGR02765
762903006174	DNA photolyase; Region: DNA_photolyase; pfam00875
762903006175	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
762903006176	active site
762903006177	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
762903006178	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
762903006179	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
762903006180	active site
762903006181	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903006182	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903006183	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
762903006184	putative catalytic site [active]
762903006185	putative metal binding site [ion binding]; other site
762903006186	putative phosphate binding site [ion binding]; other site
762903006187	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
762903006188	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
762903006189	putative catalytic site [active]
762903006190	putative metal binding site [ion binding]; other site
762903006191	putative phosphate binding site [ion binding]; other site
762903006192	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903006193	SusD family; Region: SusD; pfam07980
762903006194	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903006195	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903006196	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
762903006197	FecR protein; Region: FecR; pfam04773
762903006198	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903006199	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903006200	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903006201	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
762903006202	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
762903006203	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
762903006204	Uncharacterized conserved protein [Function unknown]; Region: COG2968
762903006205	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
762903006206	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
762903006207	dimer interface [polypeptide binding]; other site
762903006208	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903006209	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
762903006210	dimer interface [polypeptide binding]; other site
762903006211	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903006212	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903006213	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
762903006214	dimer interface [polypeptide binding]; other site
762903006215	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
762903006216	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
762903006217	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903006218	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903006219	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903006220	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903006221	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
762903006222	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903006223	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903006224	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
762903006225	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903006226	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903006227	active site
762903006228	metal binding site [ion binding]; metal-binding site
762903006229	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903006230	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903006231	ligand binding site [chemical binding]; other site
762903006232	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903006233	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903006234	ligand binding site [chemical binding]; other site
762903006235	flexible hinge region; other site
762903006236	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903006237	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903006238	Cadherin tandem repeat domain; Region: Cadherin_repeat; cd11304
762903006239	Ca2+ binding site [ion binding]; other site
762903006240	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903006241	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903006242	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903006243	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
762903006244	Phage Tail Collar Domain; Region: Collar; pfam07484
762903006245	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
762903006246	Phage Tail Collar Domain; Region: Collar; pfam07484
762903006247	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
762903006248	Phage Tail Collar Domain; Region: Collar; pfam07484
762903006249	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
762903006250	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
762903006251	active site
762903006252	substrate binding site [chemical binding]; other site
762903006253	cosubstrate binding site; other site
762903006254	catalytic site [active]
762903006255	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
762903006256	substrate binding site [chemical binding]; other site
762903006257	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
762903006258	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
762903006259	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
762903006260	Histidine kinase; Region: HisKA_2; pfam07568
762903006261	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006262	ATP binding site [chemical binding]; other site
762903006263	Mg2+ binding site [ion binding]; other site
762903006264	G-X-G motif; other site
762903006265	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006266	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
762903006267	active site
762903006268	phosphorylation site [posttranslational modification]
762903006269	intermolecular recognition site; other site
762903006270	dimerization interface [polypeptide binding]; other site
762903006271	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
762903006272	DNA binding residues [nucleotide binding]
762903006273	dimerization interface [polypeptide binding]; other site
762903006274	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903006275	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
762903006276	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
762903006277	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
762903006278	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
762903006279	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
762903006280	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
762903006281	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
762903006282	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
762903006283	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
762903006284	Interdomain contacts; other site
762903006285	Cytokine receptor motif; other site
762903006286	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903006287	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903006288	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903006289	seryl-tRNA synthetase; Provisional; Region: PRK05431
762903006290	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
762903006291	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
762903006292	dimer interface [polypeptide binding]; other site
762903006293	active site
762903006294	motif 1; other site
762903006295	motif 2; other site
762903006296	motif 3; other site
762903006297	Predicted methyltransferases [General function prediction only]; Region: COG0313
762903006298	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
762903006299	putative SAM binding site [chemical binding]; other site
762903006300	putative homodimer interface [polypeptide binding]; other site
762903006301	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
762903006302	CoA binding domain; Region: CoA_binding; smart00881
762903006303	CoA-ligase; Region: Ligase_CoA; pfam00549
762903006304	methionine sulfoxide reductase B; Provisional; Region: PRK05508
762903006305	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
762903006306	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
762903006307	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
762903006308	putative substrate binding site [chemical binding]; other site
762903006309	putative ATP binding site [chemical binding]; other site
762903006310	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
762903006311	methionine sulfoxide reductase B; Provisional; Region: PRK05508
762903006312	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
762903006313	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
762903006314	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
762903006315	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903006316	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
762903006317	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
762903006318	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
762903006319	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
762903006320	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903006321	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903006322	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903006323	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
762903006324	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
762903006325	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
762903006326	NodB motif; other site
762903006327	active site
762903006328	catalytic site [active]
762903006329	metal binding site [ion binding]; metal-binding site
762903006330	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903006331	non-specific DNA binding site [nucleotide binding]; other site
762903006332	salt bridge; other site
762903006333	sequence-specific DNA binding site [nucleotide binding]; other site
762903006334	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903006335	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903006336	ligand binding site [chemical binding]; other site
762903006337	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903006338	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903006339	ligand binding site [chemical binding]; other site
762903006340	aconitate hydratase; Validated; Region: PRK07229
762903006341	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Mitochondrial; cd01584
762903006342	substrate binding site [chemical binding]; other site
762903006343	ligand binding site [chemical binding]; other site
762903006344	Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes...; Region: AcnA_Mitochon_Swivel; cd01578
762903006345	substrate binding site [chemical binding]; other site
762903006346	Peptidase C10 family; Region: Peptidase_C10; pfam01640
762903006347	Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: MutS; COG0249
762903006348	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903006349	Walker A/P-loop; other site
762903006350	ATP binding site [chemical binding]; other site
762903006351	Q-loop/lid; other site
762903006352	ABC transporter signature motif; other site
762903006353	Walker B; other site
762903006354	D-loop; other site
762903006355	H-loop/switch region; other site
762903006356	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
762903006357	AsmA family; Region: AsmA; pfam05170
762903006358	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
762903006359	Cytochrome b5-like Heme/Steroid binding domain; Region: Cyt-b5; cl02041
762903006360	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
762903006361	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903006362	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903006363	DNA binding residues [nucleotide binding]
762903006364	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
762903006365	FAD binding domain; Region: FAD_binding_4; pfam01565
762903006366	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
762903006367	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
762903006368	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
762903006369	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
762903006370	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903006371	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903006372	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903006373	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
762903006374	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
762903006375	Ligand Binding Site [chemical binding]; other site
762903006376	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
762903006377	Ligand Binding Site [chemical binding]; other site
762903006378	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
762903006379	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
762903006380	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
762903006381	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
762903006382	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
762903006383	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903006384	PIF1-like helicase; Region: PIF1; pfam05970
762903006385	Walker A motif; other site
762903006386	ATP binding site [chemical binding]; other site
762903006387	Walker B motif; other site
762903006388	Family description; Region: UvrD_C_2; pfam13538
762903006389	HRDC domain; Region: HRDC; pfam00570
762903006390	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
762903006391	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
762903006392	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
762903006393	enolase; Provisional; Region: eno; PRK00077
762903006394	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
762903006395	dimer interface [polypeptide binding]; other site
762903006396	metal binding site [ion binding]; metal-binding site
762903006397	substrate binding pocket [chemical binding]; other site
762903006398	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
762903006399	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
762903006400	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
762903006401	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
762903006402	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
762903006403	Transcriptional regulator; Region: Rrf2; pfam02082
762903006404	Predicted transcriptional regulator [Transcription]; Region: COG1959
762903006405	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
762903006406	NADH(P)-binding; Region: NAD_binding_10; pfam13460
762903006407	NAD binding site [chemical binding]; other site
762903006408	substrate binding site [chemical binding]; other site
762903006409	putative active site [active]
762903006410	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
762903006411	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
762903006412	putative active site [active]
762903006413	metal binding site [ion binding]; metal-binding site
762903006414	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
762903006415	DEAD-like helicases superfamily; Region: DEXDc; smart00487
762903006416	ATP binding site [chemical binding]; other site
762903006417	putative Mg++ binding site [ion binding]; other site
762903006418	Septum formation initiator; Region: DivIC; pfam04977
762903006419	Predicted membrane protein [Function unknown]; Region: COG2860
762903006420	UPF0126 domain; Region: UPF0126; pfam03458
762903006421	UPF0126 domain; Region: UPF0126; pfam03458
762903006422	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
762903006423	metal ion-dependent adhesion site (MIDAS); other site
762903006424	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
762903006425	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
762903006426	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
762903006427	NAD(P) binding site [chemical binding]; other site
762903006428	homotetramer interface [polypeptide binding]; other site
762903006429	homodimer interface [polypeptide binding]; other site
762903006430	active site
762903006431	malate:quinone oxidoreductase; Validated; Region: PRK05257
762903006432	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
762903006433	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
762903006434	DEAD-like helicases superfamily; Region: DEXDc; smart00487
762903006435	ATP binding site [chemical binding]; other site
762903006436	Mg++ binding site [ion binding]; other site
762903006437	motif III; other site
762903006438	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903006439	nucleotide binding region [chemical binding]; other site
762903006440	ATP-binding site [chemical binding]; other site
762903006441	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
762903006442	RNA binding site [nucleotide binding]; other site
762903006443	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903006444	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
762903006445	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
762903006446	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
762903006447	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
762903006448	dimerization interface 3.5A [polypeptide binding]; other site
762903006449	active site
762903006450	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
762903006451	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
762903006452	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
762903006453	Walker A/P-loop; other site
762903006454	ATP binding site [chemical binding]; other site
762903006455	Q-loop/lid; other site
762903006456	ABC transporter signature motif; other site
762903006457	Walker B; other site
762903006458	D-loop; other site
762903006459	H-loop/switch region; other site
762903006460	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
762903006461	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
762903006462	putative active site [active]
762903006463	catalytic triad [active]
762903006464	putative dimer interface [polypeptide binding]; other site
762903006465	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903006466	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903006467	SusD family; Region: SusD; pfam07980
762903006468	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903006469	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903006470	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903006471	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903006472	Heparinase II/III-like protein; Region: Hepar_II_III; cl15421
762903006473	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903006474	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903006475	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903006476	Two component regulator propeller; Region: Reg_prop; pfam07494
762903006477	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903006478	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903006479	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903006480	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903006481	dimer interface [polypeptide binding]; other site
762903006482	phosphorylation site [posttranslational modification]
762903006483	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006484	ATP binding site [chemical binding]; other site
762903006485	Mg2+ binding site [ion binding]; other site
762903006486	G-X-G motif; other site
762903006487	Response regulator receiver domain; Region: Response_reg; pfam00072
762903006488	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006489	active site
762903006490	phosphorylation site [posttranslational modification]
762903006491	intermolecular recognition site; other site
762903006492	dimerization interface [polypeptide binding]; other site
762903006493	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903006494	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903006495	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
762903006496	Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893
762903006497	NAD synthetase; Provisional; Region: PRK13981
762903006498	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
762903006499	multimer interface [polypeptide binding]; other site
762903006500	active site
762903006501	catalytic triad [active]
762903006502	protein interface 1 [polypeptide binding]; other site
762903006503	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
762903006504	homodimer interface [polypeptide binding]; other site
762903006505	NAD binding pocket [chemical binding]; other site
762903006506	ATP binding pocket [chemical binding]; other site
762903006507	Mg binding site [ion binding]; other site
762903006508	active-site loop [active]
762903006509	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
762903006510	gliding motility-associated lipoprotein GldB; Region: GldB_lipo; TIGR03514
762903006511	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
762903006512	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
762903006513	active site
762903006514	nucleophile elbow; other site
762903006515	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
762903006516	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903006517	dimer interface [polypeptide binding]; other site
762903006518	phosphorylation site [posttranslational modification]
762903006519	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006520	ATP binding site [chemical binding]; other site
762903006521	Mg2+ binding site [ion binding]; other site
762903006522	G-X-G motif; other site
762903006523	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903006524	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006525	active site
762903006526	phosphorylation site [posttranslational modification]
762903006527	intermolecular recognition site; other site
762903006528	dimerization interface [polypeptide binding]; other site
762903006529	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
762903006530	core domain interface [polypeptide binding]; other site
762903006531	delta subunit interface [polypeptide binding]; other site
762903006532	epsilon subunit interface [polypeptide binding]; other site
762903006533	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
762903006534	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
762903006535	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
762903006536	beta subunit interaction interface [polypeptide binding]; other site
762903006537	Walker A motif; other site
762903006538	ATP binding site [chemical binding]; other site
762903006539	Walker B motif; other site
762903006540	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
762903006541	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
762903006542	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
762903006543	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
762903006544	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
762903006545	ATP synthase subunit C; Region: ATP-synt_C; cl00466
762903006546	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
762903006547	ATP synthase A chain; Region: ATP-synt_A; cl00413
762903006548	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
762903006549	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
762903006550	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
762903006551	Peptidase family M23; Region: Peptidase_M23; pfam01551
762903006552	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903006553	binding surface
762903006554	TPR motif; other site
762903006555	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
762903006556	Transglycosylase; Region: Transgly; pfam00912
762903006557	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
762903006558	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
762903006559	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
762903006560	GIY-YIG motif/motif A; other site
762903006561	active site
762903006562	catalytic site [active]
762903006563	putative DNA binding site [nucleotide binding]; other site
762903006564	metal binding site [ion binding]; metal-binding site
762903006565	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
762903006566	gliding motility associated protien GldN; Region: GldN; TIGR03523
762903006567	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
762903006568	GldM N-terminal domain; Region: GldM_N; pfam12081
762903006569	GldM C-terminal domain; Region: GldM_C; pfam12080
762903006570	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
762903006571	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
762903006572	gliding motility-associated lipoprotein GldK; Region: GldK; TIGR03525
762903006573	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
762903006574	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
762903006575	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
762903006576	active site
762903006577	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
762903006578	Surface antigen; Region: Bac_surface_Ag; pfam01103
762903006579	Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]; Region: HemN; COG0635
762903006580	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903006581	FeS/SAM binding site; other site
762903006582	HemN C-terminal domain; Region: HemN_C; pfam06969
762903006583	11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; Region: 11beta-HSD1_like_SDR_c; cd05332
762903006584	short chain dehydrogenase; Provisional; Region: PRK06181
762903006585	NADP binding site [chemical binding]; other site
762903006586	homodimer interface [polypeptide binding]; other site
762903006587	substrate binding site [chemical binding]; other site
762903006588	active site
762903006589	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006590	active site
762903006591	phosphorylation site [posttranslational modification]
762903006592	intermolecular recognition site; other site
762903006593	dimerization interface [polypeptide binding]; other site
762903006594	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903006595	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903006596	active site
762903006597	metal binding site [ion binding]; metal-binding site
762903006598	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
762903006599	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903006600	ligand binding site [chemical binding]; other site
762903006601	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
762903006602	putative active site [active]
762903006603	GIY-YIG motif/motif A; other site
762903006604	putative metal binding site [ion binding]; other site
762903006605	Recombination protein O N terminal; Region: RecO_N; pfam11967
762903006606	Recombination protein O C terminal; Region: RecO_C; pfam02565
762903006607	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903006608	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
762903006609	Histidine kinase; Region: His_kinase; pfam06580
762903006610	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006611	ATP binding site [chemical binding]; other site
762903006612	Mg2+ binding site [ion binding]; other site
762903006613	G-X-G motif; other site
762903006614	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
762903006615	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006616	active site
762903006617	phosphorylation site [posttranslational modification]
762903006618	intermolecular recognition site; other site
762903006619	dimerization interface [polypeptide binding]; other site
762903006620	LytTr DNA-binding domain; Region: LytTR; smart00850
762903006621	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903006622	TIGR01777 family protein; Region: yfcH
762903006623	NAD(P) binding site [chemical binding]; other site
762903006624	active site
762903006625	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
762903006626	dimer interface [polypeptide binding]; other site
762903006627	[2Fe-2S] cluster binding site [ion binding]; other site
762903006628	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
762903006629	lipoprotein signal peptidase; Provisional; Region: PRK14788
762903006630	lipoprotein signal peptidase; Provisional; Region: PRK14787
762903006631	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
762903006632	isoleucyl-tRNA synthetase; Region: ileS; TIGR00392
762903006633	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903006634	active site
762903006635	HIGH motif; other site
762903006636	nucleotide binding site [chemical binding]; other site
762903006637	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
762903006638	active site
762903006639	KMSKS motif; other site
762903006640	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
762903006641	tRNA binding surface [nucleotide binding]; other site
762903006642	anticodon binding site; other site
762903006643	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
762903006644	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903006645	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006646	active site
762903006647	phosphorylation site [posttranslational modification]
762903006648	intermolecular recognition site; other site
762903006649	dimerization interface [polypeptide binding]; other site
762903006650	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
762903006651	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
762903006652	Protein export membrane protein; Region: SecD_SecF; cl14618
762903006653	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903006654	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903006655	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903006656	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
762903006657	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
762903006658	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
762903006659	protein binding site [polypeptide binding]; other site
762903006660	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
762903006661	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
762903006662	acyl-activating enzyme (AAE) consensus motif; other site
762903006663	putative AMP binding site [chemical binding]; other site
762903006664	putative active site [active]
762903006665	putative CoA binding site [chemical binding]; other site
762903006666	Uncharacterized conserved protein [Function unknown]; Region: COG1262
762903006667	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
762903006668	Glycosyl hydrolases family 11; Region: Glyco_hydro_11; pfam00457
762903006669	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
762903006670	MG2 domain; Region: A2M_N; pfam01835
762903006671	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
762903006672	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
762903006673	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903006674	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903006675	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903006676	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495
762903006677	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
762903006678	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495
762903006679	Domain of unknown function (DUF1735); Region: DUF1735; pfam08522
762903006680	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903006681	SusD family; Region: SusD; pfam07980
762903006682	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903006683	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
762903006684	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903006685	SusD family; Region: SusD; pfam07980
762903006686	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903006687	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903006688	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
762903006689	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903006690	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903006691	Two component regulator propeller; Region: Reg_prop; pfam07494
762903006692	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903006693	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903006694	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903006695	dimer interface [polypeptide binding]; other site
762903006696	phosphorylation site [posttranslational modification]
762903006697	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006698	ATP binding site [chemical binding]; other site
762903006699	Mg2+ binding site [ion binding]; other site
762903006700	G-X-G motif; other site
762903006701	Response regulator receiver domain; Region: Response_reg; pfam00072
762903006702	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006703	active site
762903006704	phosphorylation site [posttranslational modification]
762903006705	intermolecular recognition site; other site
762903006706	dimerization interface [polypeptide binding]; other site
762903006707	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903006708	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903006709	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
762903006710	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_2; cd09001
762903006711	active site
762903006712	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
762903006713	substrate binding site [chemical binding]; other site
762903006714	active site
762903006715	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
762903006716	metal binding site [ion binding]; metal-binding site
762903006717	ligand binding site [chemical binding]; other site
762903006718	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
762903006719	substrate binding site [chemical binding]; other site
762903006720	active site
762903006721	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
762903006722	metal binding site [ion binding]; metal-binding site
762903006723	ligand binding site [chemical binding]; other site
762903006724	PA14 domain; Region: PA14; cl08459
762903006725	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
762903006726	Glycosyl hydrolases family 31; Region: Glyco_hydro_31; pfam01055
762903006727	active site
762903006728	catalytic site [active]
762903006729	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
762903006730	NPCBM/NEW2 domain; Region: NPCBM; pfam08305
762903006731	He_PIG associated, NEW1 domain of bacterial glycohydrolase; Region: He_PIG_assoc; pfam10632
762903006732	alpha-galactosidase; Region: PLN02808; cl17638
762903006733	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
762903006734	substrate binding site [chemical binding]; other site
762903006735	active site
762903006736	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
762903006737	metal binding site [ion binding]; metal-binding site
762903006738	ligand binding site [chemical binding]; other site
762903006739	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
762903006740	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
762903006741	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
762903006742	putative active site [active]
762903006743	putative catalytic site [active]
762903006744	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
762903006745	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903006746	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
762903006747	Putative esterase; Region: Esterase; pfam00756
762903006748	N-terminal Early set domain associated with the catalytic domain of esterase; Region: E_set_Esterase_N; cd02858
762903006749	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
762903006750	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
762903006751	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
762903006752	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
762903006753	inhibitor binding site; inhibition site
762903006754	active site
762903006755	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
762903006756	active site
762903006757	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
762903006758	metal binding site [ion binding]; metal-binding site
762903006759	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
762903006760	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
762903006761	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
762903006762	PA14 domain; Region: PA14; cl08459
762903006763	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
762903006764	Response regulator receiver domain; Region: Response_reg; pfam00072
762903006765	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006766	active site
762903006767	phosphorylation site [posttranslational modification]
762903006768	intermolecular recognition site; other site
762903006769	dimerization interface [polypeptide binding]; other site
762903006770	CheB methylesterase; Region: CheB_methylest; pfam01339
762903006771	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
762903006772	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
762903006773	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
762903006774	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903006775	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006776	active site
762903006777	phosphorylation site [posttranslational modification]
762903006778	intermolecular recognition site; other site
762903006779	dimerization interface [polypeptide binding]; other site
762903006780	CHASE3 domain; Region: CHASE3; pfam05227
762903006781	GAF domain; Region: GAF_2; pfam13185
762903006782	GAF domain; Region: GAF_3; pfam13492
762903006783	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903006784	dimer interface [polypeptide binding]; other site
762903006785	phosphorylation site [posttranslational modification]
762903006786	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006787	ATP binding site [chemical binding]; other site
762903006788	Mg2+ binding site [ion binding]; other site
762903006789	G-X-G motif; other site
762903006790	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903006791	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006792	active site
762903006793	phosphorylation site [posttranslational modification]
762903006794	intermolecular recognition site; other site
762903006795	dimerization interface [polypeptide binding]; other site
762903006796	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903006797	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006798	active site
762903006799	phosphorylation site [posttranslational modification]
762903006800	intermolecular recognition site; other site
762903006801	Response regulator receiver domain; Region: Response_reg; pfam00072
762903006802	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006803	active site
762903006804	phosphorylation site [posttranslational modification]
762903006805	intermolecular recognition site; other site
762903006806	dimerization interface [polypeptide binding]; other site
762903006807	Response regulator receiver domain; Region: Response_reg; pfam00072
762903006808	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006809	active site
762903006810	phosphorylation site [posttranslational modification]
762903006811	intermolecular recognition site; other site
762903006812	dimerization interface [polypeptide binding]; other site
762903006813	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
762903006814	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903006815	dimer interface [polypeptide binding]; other site
762903006816	phosphorylation site [posttranslational modification]
762903006817	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006818	ATP binding site [chemical binding]; other site
762903006819	Mg2+ binding site [ion binding]; other site
762903006820	G-X-G motif; other site
762903006821	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
762903006822	MarR family; Region: MarR_2; pfam12802
762903006823	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
762903006824	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
762903006825	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
762903006826	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
762903006827	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
762903006828	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
762903006829	substrate binding site [chemical binding]; other site
762903006830	oxyanion hole (OAH) forming residues; other site
762903006831	trimer interface [polypeptide binding]; other site
762903006832	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
762903006833	four helix bundle protein; Region: TIGR02436
762903006834	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
762903006835	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
762903006836	dimer interface [polypeptide binding]; other site
762903006837	active site
762903006838	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
762903006839	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
762903006840	active site
762903006841	chaperone protein DnaJ; Provisional; Region: PRK14299
762903006842	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
762903006843	HSP70 interaction site [polypeptide binding]; other site
762903006844	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
762903006845	substrate binding site [polypeptide binding]; other site
762903006846	dimer interface [polypeptide binding]; other site
762903006847	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
762903006848	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
762903006849	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
762903006850	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
762903006851	peptidyl-prolyl isomerase, gliding motility-associated; Region: ppisom_GldI; TIGR03516
762903006852	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
762903006853	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903006854	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903006855	active site
762903006856	phosphorylation site [posttranslational modification]
762903006857	intermolecular recognition site; other site
762903006858	dimerization interface [polypeptide binding]; other site
762903006859	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
762903006860	DNA binding site [nucleotide binding]
762903006861	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903006862	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903006863	dimer interface [polypeptide binding]; other site
762903006864	phosphorylation site [posttranslational modification]
762903006865	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903006866	ATP binding site [chemical binding]; other site
762903006867	Mg2+ binding site [ion binding]; other site
762903006868	G-X-G motif; other site
762903006869	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
762903006870	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903006871	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
762903006872	binding surface
762903006873	TPR motif; other site
762903006874	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
762903006875	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
762903006876	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
762903006877	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903006878	ligand binding site [chemical binding]; other site
762903006879	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
762903006880	Protein of unknown function (DUF420); Region: DUF420; pfam04238
762903006881	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
762903006882	Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; pfam03626
762903006883	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
762903006884	Subunit I/III interface [polypeptide binding]; other site
762903006885	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cd00386
762903006886	Subunit I/III interface [polypeptide binding]; other site
762903006887	protoheme IX farnesyltransferase; Region: cyoE_ctaB; TIGR01473
762903006888	UbiA prenyltransferase family; Region: UbiA; pfam01040
762903006889	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
762903006890	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
762903006891	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
762903006892	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
762903006893	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
762903006894	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
762903006895	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
762903006896	Protein of unknown function (DUF3341); Region: DUF3341; pfam11821
762903006897	Polysulphide reductase [Energy production and conversion]; Region: COG5557; cl17901
762903006898	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
762903006899	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
762903006900	molybdopterin cofactor binding site; other site
762903006901	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
762903006902	The MopB_CT_PHLH CD includes a group of related uncharacterized putative hydrogenase-like homologs (PHLH) of molybdopterin binding proteins. This CD is of the PHLH region homologous to the conserved molybdopterin-binding C-terminal (MopB_CT) region...; Region: MopB_CT_PHLH; cd02784
762903006903	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
762903006904	4Fe-4S binding domain; Region: Fer4_2; pfam12797
762903006905	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
762903006906	Cytochrome c; Region: Cytochrom_C; pfam00034
762903006907	Heme-binding domain of the class III cytochrome C family and related proteins; Region: Cytochrom_C3; cd08168
762903006908	heme-binding residues [chemical binding]; other site
762903006909	deoxyhypusine synthase; Region: dhys; TIGR00321
762903006910	Deoxyhypusine synthase; Region: DS; cl00826
762903006911	Deoxyhypusine synthase; Region: DS; cl00826
762903006912	Surface antigen; Region: Bac_surface_Ag; pfam01103
762903006913	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
762903006914	active site
762903006915	catalytic residues [active]
762903006916	Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; Region: Fascin; cl00187
762903006917	PKC phosphorylation site [posttranslational modification]; other site
762903006918	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903006919	Glycosyl hydrolase catalytic core; Region: Glyco_hydro_cc; pfam11790
762903006920	M26 IgA1-specific Metallo-endopeptidase N-terminal region; Region: Peptidase_M26_N; pfam05342
762903006921	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903006922	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903006923	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903006924	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903006925	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903006926	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
762903006927	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903006928	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
762903006929	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
762903006930	beta-D-glucuronidase; Provisional; Region: PRK10150
762903006931	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903006932	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903006933	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903006934	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
762903006935	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
762903006936	Methyltransferase domain; Region: Methyltransf_24; pfam13578
762903006937	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
762903006938	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
762903006939	amphipathic channel; other site
762903006940	Asn-Pro-Ala signature motifs; other site
762903006941	Two component regulator propeller; Region: Reg_prop; pfam07494
762903006942	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
762903006943	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903006944	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903006945	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903006946	HEAT repeats; Region: HEAT_2; pfam13646
762903006947	HEAT repeats; Region: HEAT_2; pfam13646
762903006948	HEAT repeats; Region: HEAT_2; pfam13646
762903006949	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903006950	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903006951	peptide chain release factor 2; Validated; Region: prfB; PRK00578
762903006952	This domain is found in peptide chain release factors; Region: PCRF; smart00937
762903006953	RF-1 domain; Region: RF-1; pfam00472
762903006954	bacillithiol system protein YtxJ; Region: B_thiol_YtxJ; TIGR04019
762903006955	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
762903006956	homopentamer interface [polypeptide binding]; other site
762903006957	active site
762903006958	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
762903006959	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903006960	binding surface
762903006961	TPR motif; other site
762903006962	recombination protein F; Reviewed; Region: recF; PRK00064
762903006963	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903006964	Walker A/P-loop; other site
762903006965	ATP binding site [chemical binding]; other site
762903006966	Q-loop/lid; other site
762903006967	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903006968	ABC transporter signature motif; other site
762903006969	Walker B; other site
762903006970	D-loop; other site
762903006971	H-loop/switch region; other site
762903006972	Protein of unknown function (DUF721); Region: DUF721; pfam05258
762903006973	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
762903006974	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
762903006975	5S rRNA interface [nucleotide binding]; other site
762903006976	CTC domain interface [polypeptide binding]; other site
762903006977	L16 interface [polypeptide binding]; other site
762903006978	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
762903006979	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
762903006980	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
762903006981	active site
762903006982	YceI-like domain; Region: YceI; pfam04264
762903006983	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903006984	Homoserine O-succinyltransferase; Region: HTS; pfam04204
762903006985	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
762903006986	proposed active site lysine [active]
762903006987	conserved cys residue [active]
762903006988	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
762903006989	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903006990	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903006991	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903006992	DNA binding residues [nucleotide binding]
762903006993	FecR protein; Region: FecR; pfam04773
762903006994	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903006995	Secretin and TonB N terminus short domain; Region: STN; pfam07660
762903006996	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903006997	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903006998	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903006999	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903007000	SusD family; Region: SusD; pfam07980
762903007001	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
762903007002	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
762903007003	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
762903007004	dimer interface [polypeptide binding]; other site
762903007005	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
762903007006	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
762903007007	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903007008	nucleotide binding region [chemical binding]; other site
762903007009	ATP-binding site [chemical binding]; other site
762903007010	SEC-C motif; Region: SEC-C; pfam02810
762903007011	Sporulation related domain; Region: SPOR; pfam05036
762903007012	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
762903007013	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
762903007014	metal binding site [ion binding]; metal-binding site
762903007015	dimer interface [polypeptide binding]; other site
762903007016	Patched family; Region: Patched; pfam02460
762903007017	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903007018	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903007019	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903007020	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
762903007021	active site
762903007022	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
762903007023	catalytic tetrad [active]
762903007024	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
762903007025	classical (c) SDRs; Region: SDR_c; cd05233
762903007026	NAD(P) binding site [chemical binding]; other site
762903007027	active site
762903007028	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
762903007029	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
762903007030	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
762903007031	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
762903007032	DNA primase; Validated; Region: dnaG; PRK05667
762903007033	CHC2 zinc finger; Region: zf-CHC2; pfam01807
762903007034	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
762903007035	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
762903007036	active site
762903007037	metal binding site [ion binding]; metal-binding site
762903007038	interdomain interaction site; other site
762903007039	hypothetical protein; Reviewed; Region: PRK12497
762903007040	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
762903007041	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
762903007042	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
762903007043	active site
762903007044	Zn binding site [ion binding]; other site
762903007045	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903007046	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903007047	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
762903007048	N-terminal plug; other site
762903007049	ligand-binding site [chemical binding]; other site
762903007050	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
762903007051	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
762903007052	intracellular protease, PfpI family; Region: PfpI; TIGR01382
762903007053	conserved cys residue [active]
762903007054	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
762903007055	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
762903007056	active site
762903007057	dimer interface [polypeptide binding]; other site
762903007058	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
762903007059	dimer interface [polypeptide binding]; other site
762903007060	active site
762903007061	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
762903007062	catalytic residues [active]
762903007063	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903007064	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903007065	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903007066	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903007067	GLPGLI family protein; Region: GLPGLI; TIGR01200
762903007068	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903007069	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903007070	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903007071	CHAD domain; Region: CHAD; cl10506
762903007072	Uncharacterized conserved protein [Function unknown]; Region: COG2353
762903007073	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
762903007074	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
762903007075	Cl- selectivity filter; other site
762903007076	Cl- binding residues [ion binding]; other site
762903007077	pore gating glutamate residue; other site
762903007078	dimer interface [polypeptide binding]; other site
762903007079	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
762903007080	CAAX protease self-immunity; Region: Abi; pfam02517
762903007081	Calx-beta domain; Region: Calx-beta; cl02522
762903007082	Calx-beta domain; Region: Calx-beta; cl02522
762903007083	Calx-beta domain; Region: Calx-beta; cl02522
762903007084	Calx-beta domain; Region: Calx-beta; cl02522
762903007085	Calx-beta domain; Region: Calx-beta; cl02522
762903007086	Calx-beta domain; Region: Calx-beta; cl02522
762903007087	Calx-beta domain; Region: Calx-beta; cl02522
762903007088	Calx-beta domain; Region: Calx-beta; cl02522
762903007089	Calx-beta domain; Region: Calx-beta; cl02522
762903007090	Calx-beta domain; Region: Calx-beta; cl02522
762903007091	Calx-beta domain; Region: Calx-beta; cl02522
762903007092	Calx-beta domain; Region: Calx-beta; pfam03160
762903007093	Calx-beta domain; Region: Calx-beta; cl02522
762903007094	Calx-beta domain; Region: Calx-beta; cl02522
762903007095	Calx-beta domain; Region: Calx-beta; cl02522
762903007096	Calx-beta domain; Region: Calx-beta; cl02522
762903007097	Calx-beta domain; Region: Calx-beta; cl02522
762903007098	Calx-beta domain; Region: Calx-beta; cl02522
762903007099	Calx-beta domain; Region: Calx-beta; cl02522
762903007100	Calx-beta domain; Region: Calx-beta; cl02522
762903007101	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903007102	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
762903007103	active site
762903007104	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903007105	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903007106	DNA binding site [nucleotide binding]
762903007107	domain linker motif; other site
762903007108	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903007109	dimerization interface [polypeptide binding]; other site
762903007110	ligand binding site [chemical binding]; other site
762903007111	Alpha-glucuronidase [Carbohydrate transport and metabolism]; Region: AguA; COG3661
762903007112	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
762903007113	Glycosyl hydrolase family 67 C-terminus; Region: Glyco_hydro_67C; pfam07477
762903007114	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
762903007115	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
762903007116	substrate binding site [chemical binding]; other site
762903007117	active site
762903007118	Cytochrome C subunit of the bacterial photosynthetic reaction center; Region: CytoC_RC; cl12263
762903007119	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903007120	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903007121	Domain of unknown function (DUF303); Region: DUF303; pfam03629
762903007122	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
762903007123	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
762903007124	inhibitor binding site; inhibition site
762903007125	active site
762903007126	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903007127	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903007128	SusD family; Region: SusD; pfam07980
762903007129	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903007130	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903007131	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903007132	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903007133	mannonate dehydratase; Region: uxuA; TIGR00695
762903007134	mannonate dehydratase; Provisional; Region: PRK03906
762903007135	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903007136	Major Facilitator Superfamily; Region: MFS_1; pfam07690
762903007137	putative substrate translocation pore; other site
762903007138	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
762903007139	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
762903007140	active site
762903007141	intersubunit interface [polypeptide binding]; other site
762903007142	catalytic residue [active]
762903007143	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
762903007144	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
762903007145	substrate binding site [chemical binding]; other site
762903007146	ATP binding site [chemical binding]; other site
762903007147	Glucuronate isomerase; Region: UxaC; pfam02614
762903007148	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
762903007149	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
762903007150	galactarate dehydratase; Region: galactar-dH20; TIGR03248
762903007151	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
762903007152	altronate oxidoreductase; Provisional; Region: PRK03643
762903007153	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
762903007154	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
762903007155	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
762903007156	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903007157	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903007158	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
762903007159	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903007160	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903007161	active site
762903007162	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
762903007163	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
762903007164	active site
762903007165	putative DNA-binding cleft [nucleotide binding]; other site
762903007166	dimer interface [polypeptide binding]; other site
762903007167	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cl00298
762903007168	active site
762903007169	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
762903007170	putative active site [active]
762903007171	OsmC-like protein; Region: OsmC; pfam02566
762903007172	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
762903007173	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
762903007174	putative active site [active]
762903007175	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
762903007176	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
762903007177	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
762903007178	protein binding site [polypeptide binding]; other site
762903007179	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
762903007180	Catalytic dyad [active]
762903007181	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cl07889
762903007182	peptidase domain interface [polypeptide binding]; other site
762903007183	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
762903007184	peptide chain release factor 1; Validated; Region: prfA; PRK00591
762903007185	This domain is found in peptide chain release factors; Region: PCRF; smart00937
762903007186	RF-1 domain; Region: RF-1; pfam00472
762903007187	envelope glycoprotein H; Provisional; Region: PHA03295
762903007188	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903007189	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
762903007190	putative active site [active]
762903007191	putative metal binding site [ion binding]; other site
762903007192	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
762903007193	putative SAM binding site [chemical binding]; other site
762903007194	homodimer interface [polypeptide binding]; other site
762903007195	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
762903007196	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
762903007197	active site
762903007198	dinuclear metal binding site [ion binding]; other site
762903007199	dimerization interface [polypeptide binding]; other site
762903007200	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
762903007201	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
762903007202	active site
762903007203	(T/H)XGH motif; other site
762903007204	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
762903007205	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
762903007206	catalytic site [active]
762903007207	G-X2-G-X-G-K; other site
762903007208	hypothetical protein; Provisional; Region: PRK11820
762903007209	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
762903007210	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
762903007211	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903007212	PGAP1-like protein; Region: PGAP1; pfam07819
762903007213	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903007214	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
762903007215	dimerization interface [polypeptide binding]; other site
762903007216	active site
762903007217	metal binding site [ion binding]; metal-binding site
762903007218	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
762903007219	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
762903007220	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
762903007221	dimer interface [polypeptide binding]; other site
762903007222	active site
762903007223	acyl carrier protein; Provisional; Region: acpP; PRK00982
762903007224	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
762903007225	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
762903007226	domain interfaces; other site
762903007227	active site
762903007228	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903007229	putative active site [active]
762903007230	heme pocket [chemical binding]; other site
762903007231	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903007232	PAS domain; Region: PAS_9; pfam13426
762903007233	putative active site [active]
762903007234	heme pocket [chemical binding]; other site
762903007235	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903007236	phosphorylation site [posttranslational modification]
762903007237	dimer interface [polypeptide binding]; other site
762903007238	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
762903007239	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
762903007240	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
762903007241	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
762903007242	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
762903007243	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
762903007244	protein binding site [polypeptide binding]; other site
762903007245	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
762903007246	protein binding site [polypeptide binding]; other site
762903007247	pyruvate dehydrogenase subunit beta; Validated; Region: PRK09212
762903007248	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
762903007249	alpha subunit interface [polypeptide binding]; other site
762903007250	TPP binding site [chemical binding]; other site
762903007251	heterodimer interface [polypeptide binding]; other site
762903007252	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
762903007253	Penicillinase repressor; Region: Pencillinase_R; pfam03965
762903007254	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
762903007255	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
762903007256	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
762903007257	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
762903007258	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
762903007259	protein binding site [polypeptide binding]; other site
762903007260	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
762903007261	Catalytic dyad [active]
762903007262	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
762903007263	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
762903007264	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
762903007265	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
762903007266	Histidine kinase; Region: HisKA_3; pfam07730
762903007267	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
762903007268	ATP binding site [chemical binding]; other site
762903007269	Mg2+ binding site [ion binding]; other site
762903007270	G-X-G motif; other site
762903007271	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
762903007272	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903007273	active site
762903007274	phosphorylation site [posttranslational modification]
762903007275	intermolecular recognition site; other site
762903007276	dimerization interface [polypeptide binding]; other site
762903007277	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
762903007278	DNA binding residues [nucleotide binding]
762903007279	dimerization interface [polypeptide binding]; other site
762903007280	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
762903007281	Site-specific recombinase; Region: SpecificRecomb; cl15411
762903007282	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
762903007283	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
762903007284	NADP binding site [chemical binding]; other site
762903007285	active site
762903007286	putative substrate binding site [chemical binding]; other site
762903007287	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
762903007288	YtxH-like protein; Region: YtxH; pfam12732
762903007289	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
762903007290	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
762903007291	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903007292	active site
762903007293	phosphorylation site [posttranslational modification]
762903007294	intermolecular recognition site; other site
762903007295	dimerization interface [polypeptide binding]; other site
762903007296	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903007297	Walker A motif; other site
762903007298	ATP binding site [chemical binding]; other site
762903007299	Walker B motif; other site
762903007300	arginine finger; other site
762903007301	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
762903007302	enoyl-CoA hydratase; Provisional; Region: PRK07658
762903007303	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
762903007304	substrate binding site [chemical binding]; other site
762903007305	oxyanion hole (OAH) forming residues; other site
762903007306	trimer interface [polypeptide binding]; other site
762903007307	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
762903007308	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
762903007309	putative metal binding site; other site
762903007310	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
762903007311	mce related protein; Region: MCE; pfam02470
762903007312	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
762903007313	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
762903007314	Walker A/P-loop; other site
762903007315	ATP binding site [chemical binding]; other site
762903007316	Q-loop/lid; other site
762903007317	ABC transporter signature motif; other site
762903007318	Walker B; other site
762903007319	D-loop; other site
762903007320	H-loop/switch region; other site
762903007321	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
762903007322	Permease; Region: Permease; pfam02405
762903007323	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
762903007324	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903007325	active site
762903007326	HIGH motif; other site
762903007327	nucleotide binding site [chemical binding]; other site
762903007328	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
762903007329	KMSKS motif; other site
762903007330	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
762903007331	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
762903007332	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
762903007333	generic binding surface II; other site
762903007334	ssDNA binding site; other site
762903007335	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903007336	ATP binding site [chemical binding]; other site
762903007337	putative Mg++ binding site [ion binding]; other site
762903007338	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903007339	nucleotide binding region [chemical binding]; other site
762903007340	ATP-binding site [chemical binding]; other site
762903007341	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
762903007342	homotrimer interaction site [polypeptide binding]; other site
762903007343	putative active site [active]
762903007344	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
762903007345	Thrombospondin type 3 repeat; Region: TSP_3; pfam02412
762903007346	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903007347	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903007348	ligand binding site [chemical binding]; other site
762903007349	proline aminopeptidase P II; Provisional; Region: PRK10879
762903007350	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
762903007351	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
762903007352	active site
762903007353	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
762903007354	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903007355	active site
762903007356	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
762903007357	Sulfatase; Region: Sulfatase; cl17466
762903007358	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
762903007359	GDP-Fucose binding site [chemical binding]; other site
762903007360	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
762903007361	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
762903007362	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
762903007363	Walker A/P-loop; other site
762903007364	ATP binding site [chemical binding]; other site
762903007365	Q-loop/lid; other site
762903007366	ABC transporter signature motif; other site
762903007367	Walker B; other site
762903007368	D-loop; other site
762903007369	H-loop/switch region; other site
762903007370	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903007371	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
762903007372	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903007373	active site
762903007374	Protein of unknown function (DUF563); Region: DUF563; pfam04577
762903007375	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
762903007376	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
762903007377	inhibitor-cofactor binding pocket; inhibition site
762903007378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903007379	catalytic residue [active]
762903007380	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
762903007381	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
762903007382	putative trimer interface [polypeptide binding]; other site
762903007383	putative active site [active]
762903007384	putative substrate binding site [chemical binding]; other site
762903007385	putative CoA binding site [chemical binding]; other site
762903007386	WxcM-like, C-terminal; Region: FdtA; pfam05523
762903007387	WxcM-like, C-terminal; Region: FdtA; pfam05523
762903007388	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
762903007389	Putative catalytic domain of uncharacterized prokaryotic polysaccharide deacetylases similar to bacterial PuuE allantoinases and Helicobacter pylori peptidoglycan deacetylase (HpPgdA); Region: CE4_PuuE_HpPgdA_like_2; cd10941
762903007390	putative active site [active]
762903007391	putative catalytic site [active]
762903007392	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
762903007393	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
762903007394	Ligand binding site; other site
762903007395	Putative Catalytic site; other site
762903007396	DXD motif; other site
762903007397	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
762903007398	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
762903007399	translation initiation factor IF-2; Region: IF-2; TIGR00487
762903007400	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
762903007401	G1 box; other site
762903007402	putative GEF interaction site [polypeptide binding]; other site
762903007403	GTP/Mg2+ binding site [chemical binding]; other site
762903007404	Switch I region; other site
762903007405	G2 box; other site
762903007406	G3 box; other site
762903007407	Switch II region; other site
762903007408	G4 box; other site
762903007409	G5 box; other site
762903007410	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
762903007411	Translation-initiation factor 2; Region: IF-2; pfam11987
762903007412	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
762903007413	transcription termination factor NusA; Region: NusA; TIGR01953
762903007414	NusA N-terminal domain; Region: NusA_N; pfam08529
762903007415	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
762903007416	RNA binding site [nucleotide binding]; other site
762903007417	homodimer interface [polypeptide binding]; other site
762903007418	NusA-like KH domain; Region: KH_5; pfam13184
762903007419	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
762903007420	G-X-X-G motif; other site
762903007421	ribosome maturation protein RimP; Reviewed; Region: PRK00092
762903007422	Sm and related proteins; Region: Sm_like; cl00259
762903007423	heptamer interface [polypeptide binding]; other site
762903007424	Sm1 motif; other site
762903007425	hexamer interface [polypeptide binding]; other site
762903007426	RNA binding site [nucleotide binding]; other site
762903007427	Sm2 motif; other site
762903007428	Membrane protein of unknown function; Region: DUF360; pfam04020
762903007429	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
762903007430	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903007431	catalytic residues [active]
762903007432	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
762903007433	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
762903007434	FAD binding site [chemical binding]; other site
762903007435	homotetramer interface [polypeptide binding]; other site
762903007436	substrate binding pocket [chemical binding]; other site
762903007437	catalytic base [active]
762903007438	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
762903007439	tetramerization interface [polypeptide binding]; other site
762903007440	active site
762903007441	pantoate--beta-alanine ligase; Region: panC; TIGR00018
762903007442	Pantoate-beta-alanine ligase; Region: PanC; cd00560
762903007443	active site
762903007444	ATP-binding site [chemical binding]; other site
762903007445	pantoate-binding site; other site
762903007446	HXXH motif; other site
762903007447	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
762903007448	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
762903007449	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
762903007450	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
762903007451	glutaminase active site [active]
762903007452	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
762903007453	dimer interface [polypeptide binding]; other site
762903007454	active site
762903007455	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
762903007456	dimer interface [polypeptide binding]; other site
762903007457	active site
762903007458	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
762903007459	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
762903007460	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
762903007461	dimerization interface [polypeptide binding]; other site
762903007462	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
762903007463	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
762903007464	NAD binding site [chemical binding]; other site
762903007465	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
762903007466	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
762903007467	N- and C-terminal domain interface [polypeptide binding]; other site
762903007468	active site
762903007469	catalytic site [active]
762903007470	metal binding site [ion binding]; metal-binding site
762903007471	carbohydrate binding site [chemical binding]; other site
762903007472	ATP binding site [chemical binding]; other site
762903007473	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
762903007474	carboxy-terminal protease; Provisional; Region: PRK11186
762903007475	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
762903007476	protein binding site [polypeptide binding]; other site
762903007477	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
762903007478	Catalytic dyad [active]
762903007479	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
762903007480	recombination factor protein RarA; Reviewed; Region: PRK13342
762903007481	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903007482	Walker A motif; other site
762903007483	ATP binding site [chemical binding]; other site
762903007484	Walker B motif; other site
762903007485	arginine finger; other site
762903007486	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
762903007487	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
762903007488	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
762903007489	HIGH motif; other site
762903007490	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
762903007491	active site
762903007492	KMSKS motif; other site
762903007493	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
762903007494	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
762903007495	active site
762903007496	DNA polymerase I; Provisional; Region: PRK05755
762903007497	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
762903007498	active site
762903007499	metal binding site 1 [ion binding]; metal-binding site
762903007500	putative 5' ssDNA interaction site; other site
762903007501	metal binding site 3; metal-binding site
762903007502	metal binding site 2 [ion binding]; metal-binding site
762903007503	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
762903007504	putative DNA binding site [nucleotide binding]; other site
762903007505	putative metal binding site [ion binding]; other site
762903007506	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
762903007507	active site
762903007508	catalytic site [active]
762903007509	substrate binding site [chemical binding]; other site
762903007510	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
762903007511	active site
762903007512	DNA binding site [nucleotide binding]
762903007513	catalytic site [active]
762903007514	Rhomboid family; Region: Rhomboid; pfam01694
762903007515	H+ Antiporter protein; Region: 2A0121; TIGR00900
762903007516	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903007517	putative substrate translocation pore; other site
762903007518	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
762903007519	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
762903007520	Phosphatidylserine decarboxylase; Region: PS_Dcarbxylase; cl03656
762903007521	Post-segregation antitoxin CcdA; Region: CcdA; cl02188
762903007522	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
762903007523	putative recombination protein RecB; Provisional; Region: PRK13909
762903007524	Family description; Region: UvrD_C_2; pfam13538
762903007525	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
762903007526	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
762903007527	putative ATP binding site [chemical binding]; other site
762903007528	putative substrate interface [chemical binding]; other site
762903007529	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
762903007530	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
762903007531	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
762903007532	RimM N-terminal domain; Region: RimM; pfam01782
762903007533	methionine sulfoxide reductase A; Provisional; Region: PRK14054
762903007534	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
762903007535	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
762903007536	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903007537	Walker A motif; other site
762903007538	ATP binding site [chemical binding]; other site
762903007539	Walker B motif; other site
762903007540	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
762903007541	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
762903007542	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
762903007543	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
762903007544	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
762903007545	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
762903007546	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
762903007547	putative active site [active]
762903007548	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
762903007549	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
762903007550	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
762903007551	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
762903007552	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
762903007553	nucleotide binding site [chemical binding]; other site
762903007554	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
762903007555	active site
762903007556	ribulose/triose binding site [chemical binding]; other site
762903007557	phosphate binding site [ion binding]; other site
762903007558	substrate (anthranilate) binding pocket [chemical binding]; other site
762903007559	product (indole) binding pocket [chemical binding]; other site
762903007560	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
762903007561	Glutamine amidotransferase class-I; Region: GATase; pfam00117
762903007562	glutamine binding [chemical binding]; other site
762903007563	catalytic triad [active]
762903007564	Chorismate mutase type II; Region: CM_2; cl00693
762903007565	anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564
762903007566	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
762903007567	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
762903007568	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
762903007569	dimer interface [polypeptide binding]; other site
762903007570	active site
762903007571	ADP-ribose binding site [chemical binding]; other site
762903007572	nudix motif; other site
762903007573	metal binding site [ion binding]; metal-binding site
762903007574	Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893
762903007575	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
762903007576	active site
762903007577	Cellular and retroviral pepsin-like aspartate proteases; Region: pepsin_retropepsin_like; cl11403
762903007578	inhibitor binding site; inhibition site
762903007579	catalytic motif [active]
762903007580	Catalytic residue [active]
762903007581	Active site flap [active]
762903007582	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
762903007583	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
762903007584	short chain dehydrogenase; Provisional; Region: PRK07326
762903007585	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903007586	NAD(P) binding site [chemical binding]; other site
762903007587	active site
762903007588	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
762903007589	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903007590	catalytic residues [active]
762903007591	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903007592	TPR motif; other site
762903007593	binding surface
762903007594	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903007595	binding surface
762903007596	TPR motif; other site
762903007597	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903007598	binding surface
762903007599	TPR motif; other site
762903007600	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903007601	TPR motif; other site
762903007602	binding surface
762903007603	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
762903007604	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
762903007605	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
762903007606	hexamer interface [polypeptide binding]; other site
762903007607	ligand binding site [chemical binding]; other site
762903007608	putative active site [active]
762903007609	NAD(P) binding site [chemical binding]; other site
762903007610	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903007611	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
762903007612	Response regulator receiver domain; Region: Response_reg; pfam00072
762903007613	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903007614	active site
762903007615	phosphorylation site [posttranslational modification]
762903007616	intermolecular recognition site; other site
762903007617	dimerization interface [polypeptide binding]; other site
762903007618	PglZ domain; Region: PglZ; pfam08665
762903007619	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
762903007620	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
762903007621	Zn2+ binding site [ion binding]; other site
762903007622	Mg2+ binding site [ion binding]; other site
762903007623	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
762903007624	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
762903007625	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
762903007626	trimer interface [polypeptide binding]; other site
762903007627	active site
762903007628	UDP-GlcNAc binding site [chemical binding]; other site
762903007629	lipid binding site [chemical binding]; lipid-binding site
762903007630	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
762903007631	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
762903007632	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
762903007633	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
762903007634	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
762903007635	active site
762903007636	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903007637	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
762903007638	Walker A/P-loop; other site
762903007639	ATP binding site [chemical binding]; other site
762903007640	Q-loop/lid; other site
762903007641	ABC transporter signature motif; other site
762903007642	Walker B; other site
762903007643	D-loop; other site
762903007644	elongation factor P; Validated; Region: PRK00529
762903007645	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
762903007646	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
762903007647	RNA binding site [nucleotide binding]; other site
762903007648	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
762903007649	RNA binding site [nucleotide binding]; other site
762903007650	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
762903007651	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
762903007652	Conserved hypothetical protein 2217 (DUF2460); Region: DUF2460; cl02268
762903007653	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
762903007654	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903007655	dimer interface [polypeptide binding]; other site
762903007656	phosphorylation site [posttranslational modification]
762903007657	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903007658	ATP binding site [chemical binding]; other site
762903007659	Mg2+ binding site [ion binding]; other site
762903007660	G-X-G motif; other site
762903007661	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
762903007662	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
762903007663	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
762903007664	homodecamer interface [polypeptide binding]; other site
762903007665	GTP cyclohydrolase I; Provisional; Region: PLN03044
762903007666	active site
762903007667	putative catalytic site residues [active]
762903007668	zinc binding site [ion binding]; other site
762903007669	GTP-CH-I/GFRP interaction surface; other site
762903007670	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
762903007671	active site
762903007672	futalosine nucleosidase; Region: fut_nucase; TIGR03664
762903007673	Menaquinone biosynthesis; Region: VitK2_biosynth; cl17475
762903007674	Glycerophosphodiester phosphodiesterase domain of putative Silicibacter pomeroyi glycerophosphodiester phosphodiesterase and similar proteins; Region: GDPD_SpGDE_like; cd08567
762903007675	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
762903007676	active site
762903007677	catalytic site [active]
762903007678	metal binding site [ion binding]; metal-binding site
762903007679	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
762903007680	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903007681	putative substrate translocation pore; other site
762903007682	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
762903007683	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
762903007684	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
762903007685	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
762903007686	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
762903007687	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
762903007688	active site
762903007689	catalytic triad [active]
762903007690	oxyanion hole [active]
762903007691	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
762903007692	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
762903007693	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
762903007694	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903007695	Major Facilitator Superfamily; Region: MFS_1; pfam07690
762903007696	putative substrate translocation pore; other site
762903007697	heat shock protein 90; Provisional; Region: PRK05218
762903007698	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903007699	ATP binding site [chemical binding]; other site
762903007700	Mg2+ binding site [ion binding]; other site
762903007701	G-X-G motif; other site
762903007702	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
762903007703	Histidine kinase; Region: His_kinase; pfam06580
762903007704	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
762903007705	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903007706	active site
762903007707	phosphorylation site [posttranslational modification]
762903007708	intermolecular recognition site; other site
762903007709	dimerization interface [polypeptide binding]; other site
762903007710	LytTr DNA-binding domain; Region: LytTR; smart00850
762903007711	Protein of unknown function, DUF481; Region: DUF481; cl01213
762903007712	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
762903007713	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
762903007714	putative acyl-acceptor binding pocket; other site
762903007715	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
762903007716	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
762903007717	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
762903007718	G1 box; other site
762903007719	putative GEF interaction site [polypeptide binding]; other site
762903007720	GTP/Mg2+ binding site [chemical binding]; other site
762903007721	Switch I region; other site
762903007722	G2 box; other site
762903007723	G3 box; other site
762903007724	Switch II region; other site
762903007725	G4 box; other site
762903007726	G5 box; other site
762903007727	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
762903007728	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
762903007729	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
762903007730	homotrimer interaction site [polypeptide binding]; other site
762903007731	zinc binding site [ion binding]; other site
762903007732	CDP-binding sites; other site
762903007733	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
762903007734	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
762903007735	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
762903007736	alkylhydroperoxidase AhpD family core domain; Region: ahpD_dom; TIGR00778
762903007737	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
762903007738	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
762903007739	dimer interface [polypeptide binding]; other site
762903007740	decamer (pentamer of dimers) interface [polypeptide binding]; other site
762903007741	catalytic triad [active]
762903007742	peroxidatic and resolving cysteines [active]
762903007743	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
762903007744	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903007745	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903007746	ligand binding site [chemical binding]; other site
762903007747	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
762903007748	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903007749	NAD(P) binding site [chemical binding]; other site
762903007750	active site
762903007751	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
762903007752	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
762903007753	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
762903007754	putative RNA binding site [nucleotide binding]; other site
762903007755	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903007756	S-adenosylmethionine binding site [chemical binding]; other site
762903007757	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
762903007758	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
762903007759	dimer interface [polypeptide binding]; other site
762903007760	active site
762903007761	metal binding site [ion binding]; metal-binding site
762903007762	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
762903007763	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
762903007764	CsbD-like; Region: CsbD; cl17424
762903007765	Protein of unknown function (DUF419); Region: DUF419; pfam04237
762903007766	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
762903007767	peptidase T; Region: peptidase-T; TIGR01882
762903007768	metal binding site [ion binding]; metal-binding site
762903007769	dimer interface [polypeptide binding]; other site
762903007770	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
762903007771	CoenzymeA binding site [chemical binding]; other site
762903007772	subunit interaction site [polypeptide binding]; other site
762903007773	PHB binding site; other site
762903007774	metal-dependent hydrolase; Provisional; Region: PRK13291
762903007775	DinB superfamily; Region: DinB_2; pfam12867
762903007776	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903007777	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903007778	phosphorylation site [posttranslational modification]
762903007779	dimer interface [polypeptide binding]; other site
762903007780	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903007781	ATP binding site [chemical binding]; other site
762903007782	Mg2+ binding site [ion binding]; other site
762903007783	G-X-G motif; other site
762903007784	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
762903007785	active site residue [active]
762903007786	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
762903007787	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
762903007788	putative Iron-sulfur protein interface [polypeptide binding]; other site
762903007789	proximal heme binding site [chemical binding]; other site
762903007790	distal heme binding site [chemical binding]; other site
762903007791	putative dimer interface [polypeptide binding]; other site
762903007792	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
762903007793	L-aspartate oxidase; Provisional; Region: PRK06175
762903007794	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
762903007795	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
762903007796	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
762903007797	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
762903007798	Predicted membrane protein [Function unknown]; Region: COG4758
762903007799	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
762903007800	Domain of unknown function (DUF4288); Region: DUF4288; pfam14119
762903007801	Histidine kinase; Region: His_kinase; pfam06580
762903007802	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
762903007803	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903007804	active site
762903007805	phosphorylation site [posttranslational modification]
762903007806	intermolecular recognition site; other site
762903007807	dimerization interface [polypeptide binding]; other site
762903007808	LytTr DNA-binding domain; Region: LytTR; smart00850
762903007809	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
762903007810	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
762903007811	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
762903007812	FMN binding site [chemical binding]; other site
762903007813	active site
762903007814	catalytic residues [active]
762903007815	substrate binding site [chemical binding]; other site
762903007816	CAAX protease self-immunity; Region: Abi; pfam02517
762903007817	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
762903007818	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
762903007819	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
762903007820	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
762903007821	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
762903007822	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
762903007823	RNA methyltransferase, RsmE family; Region: TIGR00046
762903007824	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
762903007825	Domain of unknown function DUF21; Region: DUF21; pfam01595
762903007826	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
762903007827	Transporter associated domain; Region: CorC_HlyC; smart01091
762903007828	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
762903007829	dimer interface [polypeptide binding]; other site
762903007830	substrate binding site [chemical binding]; other site
762903007831	metal binding sites [ion binding]; metal-binding site
762903007832	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
762903007833	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
762903007834	NADH dehydrogenase subunit 2; Provisional; Region: ND2; MTH00197
762903007835	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
762903007836	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
762903007837	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
762903007838	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
762903007839	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
762903007840	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
762903007841	NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus; Region: Oxidored_q1_C; pfam01010
762903007842	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
762903007843	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
762903007844	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
762903007845	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
762903007846	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
762903007847	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
762903007848	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
762903007849	catalytic loop [active]
762903007850	iron binding site [ion binding]; other site
762903007851	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
762903007852	NADH-quinone oxidoreductase, F subunit; Region: nuoF_fam; TIGR01959
762903007853	SLBB domain; Region: SLBB; pfam10531
762903007854	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
762903007855	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
762903007856	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
762903007857	putative dimer interface [polypeptide binding]; other site
762903007858	[2Fe-2S] cluster binding site [ion binding]; other site
762903007859	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
762903007860	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
762903007861	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
762903007862	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
762903007863	NADH dehydrogenase subunit B; Provisional; Region: PRK14820
762903007864	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
762903007865	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903007866	binding surface
762903007867	TPR motif; other site
762903007868	TPR repeat; Region: TPR_11; pfam13414
762903007869	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903007870	binding surface
762903007871	TPR motif; other site
762903007872	PBP superfamily domain; Region: PBP_like_2; pfam12849
762903007873	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
762903007874	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
762903007875	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
762903007876	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
762903007877	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
762903007878	putative rRNA binding site [nucleotide binding]; other site
762903007879	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
762903007880	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
762903007881	S-adenosylmethionine synthetase; Validated; Region: PRK05250
762903007882	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
762903007883	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
762903007884	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
762903007885	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903007886	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
762903007887	putative active cleft [active]
762903007888	dimerization interface [polypeptide binding]; other site
762903007889	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
762903007890	active site
762903007891	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
762903007892	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903007893	putative substrate translocation pore; other site
762903007894	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
762903007895	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903007896	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903007897	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cl15674
762903007898	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903007899	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903007900	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903007901	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903007902	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903007903	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903007904	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
762903007905	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
762903007906	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
762903007907	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
762903007908	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
762903007909	amidase catalytic site [active]
762903007910	Zn binding residues [ion binding]; other site
762903007911	substrate binding site [chemical binding]; other site
762903007912	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
762903007913	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
762903007914	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903007915	dimer interface [polypeptide binding]; other site
762903007916	phosphorylation site [posttranslational modification]
762903007917	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903007918	ATP binding site [chemical binding]; other site
762903007919	Mg2+ binding site [ion binding]; other site
762903007920	G-X-G motif; other site
762903007921	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
762903007922	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
762903007923	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
762903007924	active site
762903007925	catalytic residues [active]
762903007926	metal binding site [ion binding]; metal-binding site
762903007927	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903007928	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
762903007929	antiporter inner membrane protein; Provisional; Region: PRK11670
762903007930	Domain of unknown function DUF59; Region: DUF59; pfam01883
762903007931	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
762903007932	Transglycosylase; Region: Transgly; pfam00912
762903007933	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
762903007934	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
762903007935	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional; Region: PRK14501
762903007936	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
762903007937	active site
762903007938	homotetramer interface [polypeptide binding]; other site
762903007939	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
762903007940	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
762903007941	dimer interface [polypeptide binding]; other site
762903007942	FMN binding site [chemical binding]; other site
762903007943	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14521
762903007944	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
762903007945	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
762903007946	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
762903007947	active site
762903007948	catalytic site [active]
762903007949	hypothetical protein; Provisional; Region: PRK02877
762903007950	6-phosphofructokinase; Provisional; Region: PRK03202
762903007951	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
762903007952	active site
762903007953	ADP/pyrophosphate binding site [chemical binding]; other site
762903007954	dimerization interface [polypeptide binding]; other site
762903007955	allosteric effector site; other site
762903007956	fructose-1,6-bisphosphate binding site; other site
762903007957	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
762903007958	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
762903007959	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
762903007960	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
762903007961	FtsH Extracellular; Region: FtsH_ext; pfam06480
762903007962	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
762903007963	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903007964	Walker A motif; other site
762903007965	ATP binding site [chemical binding]; other site
762903007966	Walker B motif; other site
762903007967	arginine finger; other site
762903007968	Peptidase family M41; Region: Peptidase_M41; pfam01434
762903007969	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
762903007970	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
762903007971	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
762903007972	FeS/SAM binding site; other site
762903007973	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
762903007974	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
762903007975	dimer interface [polypeptide binding]; other site
762903007976	active site
762903007977	CoA binding pocket [chemical binding]; other site
762903007978	Protein of unknown function (DUF1003); Region: DUF1003; pfam06210
762903007979	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
762903007980	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903007981	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
762903007982	RmuC family; Region: RmuC; pfam02646
762903007983	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
762903007984	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
762903007985	dimer interface [polypeptide binding]; other site
762903007986	anticodon binding site; other site
762903007987	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
762903007988	homodimer interface [polypeptide binding]; other site
762903007989	motif 1; other site
762903007990	active site
762903007991	motif 2; other site
762903007992	GAD domain; Region: GAD; pfam02938
762903007993	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
762903007994	motif 3; other site
762903007995	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
762903007996	active site
762903007997	Ion transport protein; Region: Ion_trans; pfam00520
762903007998	Ion channel; Region: Ion_trans_2; pfam07885
762903007999	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
762903008000	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
762903008001	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
762903008002	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
762903008003	thiamine-monophosphate kinase; Region: thiL; TIGR01379
762903008004	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
762903008005	ATP binding site [chemical binding]; other site
762903008006	dimerization interface [polypeptide binding]; other site
762903008007	quinolinate synthetase; Provisional; Region: PRK09375
762903008008	L-aspartate oxidase; Provisional; Region: PRK09077
762903008009	L-aspartate oxidase; Provisional; Region: PRK06175
762903008010	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
762903008011	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
762903008012	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
762903008013	trimer interface [polypeptide binding]; other site
762903008014	putative metal binding site [ion binding]; other site
762903008015	Bacterial Ig-like domain; Region: Big_5; pfam13205
762903008016	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903008017	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
762903008018	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
762903008019	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
762903008020	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
762903008021	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
762903008022	Walker A/P-loop; other site
762903008023	ATP binding site [chemical binding]; other site
762903008024	Q-loop/lid; other site
762903008025	ABC transporter signature motif; other site
762903008026	Walker B; other site
762903008027	D-loop; other site
762903008028	H-loop/switch region; other site
762903008029	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
762903008030	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903008031	NAD(P) binding site [chemical binding]; other site
762903008032	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
762903008033	active site
762903008034	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
762903008035	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
762903008036	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
762903008037	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903008038	ATP binding site [chemical binding]; other site
762903008039	Mg2+ binding site [ion binding]; other site
762903008040	G-X-G motif; other site
762903008041	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
762903008042	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
762903008043	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
762903008044	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
762903008045	FtsX-like permease family; Region: FtsX; pfam02687
762903008046	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
762903008047	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903008048	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903008049	gliding motility-associated lipoprotein GldD; Region: GldD_lipo; TIGR03512
762903008050	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
762903008051	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
762903008052	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
762903008053	shikimate binding site; other site
762903008054	NAD(P) binding site [chemical binding]; other site
762903008055	(2R)-phospho-3-sulfolactate synthase (ComA); Region: ComA; pfam02679
762903008056	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903008057	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008058	binding surface
762903008059	TPR motif; other site
762903008060	TPR repeat; Region: TPR_11; pfam13414
762903008061	TPR repeat; Region: TPR_11; pfam13414
762903008062	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008063	binding surface
762903008064	TPR motif; other site
762903008065	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903008066	TPR repeat; Region: TPR_11; pfam13414
762903008067	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903008068	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008069	binding surface
762903008070	TPR motif; other site
762903008071	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008072	binding surface
762903008073	Tetratricopeptide repeat; Region: TPR_16; pfam13432
762903008074	TPR motif; other site
762903008075	DNA repair protein RadA; Provisional; Region: PRK11823
762903008076	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
762903008077	Walker A motif/ATP binding site; other site
762903008078	ATP binding site [chemical binding]; other site
762903008079	Walker B motif; other site
762903008080	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
762903008081	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
762903008082	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
762903008083	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
762903008084	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
762903008085	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
762903008086	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
762903008087	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
762903008088	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
762903008089	Ecotin; Region: Ecotin; pfam03974
762903008090	secondary substrate binding site; other site
762903008091	primary substrate binding site; other site
762903008092	inhibition loop; other site
762903008093	dimerization interface [polypeptide binding]; other site
762903008094	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
762903008095	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
762903008096	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
762903008097	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
762903008098	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
762903008099	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
762903008100	Ribosome-binding factor A; Region: RBFA; pfam02033
762903008101	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
762903008102	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
762903008103	HflX GTPase family; Region: HflX; cd01878
762903008104	G1 box; other site
762903008105	GTP/Mg2+ binding site [chemical binding]; other site
762903008106	Switch I region; other site
762903008107	G2 box; other site
762903008108	G3 box; other site
762903008109	Switch II region; other site
762903008110	G4 box; other site
762903008111	G5 box; other site
762903008112	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
762903008113	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903008114	catalytic residues [active]
762903008115	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
762903008116	AAA domain; Region: AAA_28; pfam13521
762903008117	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
762903008118	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903008119	ATP binding site [chemical binding]; other site
762903008120	putative Mg++ binding site [ion binding]; other site
762903008121	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903008122	nucleotide binding region [chemical binding]; other site
762903008123	ATP-binding site [chemical binding]; other site
762903008124	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903008125	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008126	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903008127	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903008128	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903008129	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903008130	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903008131	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903008132	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
762903008133	active site
762903008134	catalytic residues [active]
762903008135	Glycosyl hydrolase family 43; Region: GH43_ABN_2; cd08999
762903008136	putative substrate binding site [chemical binding]; other site
762903008137	active site
762903008138	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
762903008139	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
762903008140	Asp-box motif; other site
762903008141	Glycosyl hydrolase family 43; Region: GH43_bXyl_2; cd08991
762903008142	active site
762903008143	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903008144	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903008145	SusD family; Region: SusD; pfam07980
762903008146	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903008147	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008148	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903008149	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903008150	Two component regulator propeller; Region: Reg_prop; pfam07494
762903008151	Two component regulator propeller; Region: Reg_prop; pfam07494
762903008152	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903008153	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903008154	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903008155	dimer interface [polypeptide binding]; other site
762903008156	phosphorylation site [posttranslational modification]
762903008157	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903008158	ATP binding site [chemical binding]; other site
762903008159	Mg2+ binding site [ion binding]; other site
762903008160	G-X-G motif; other site
762903008161	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903008162	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903008163	active site
762903008164	phosphorylation site [posttranslational modification]
762903008165	intermolecular recognition site; other site
762903008166	dimerization interface [polypeptide binding]; other site
762903008167	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903008168	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903008169	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
762903008170	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
762903008171	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
762903008172	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903008173	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903008174	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903008175	Di-glucose binding within endoplasmic reticulum; Region: Malectin; pfam11721
762903008176	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
762903008177	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903008178	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
762903008179	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
762903008180	DNA binding residues [nucleotide binding]
762903008181	dimerization interface [polypeptide binding]; other site
762903008182	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
762903008183	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
762903008184	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
762903008185	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
762903008186	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
762903008187	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
762903008188	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
762903008189	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
762903008190	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
762903008191	Carbohydrate Binding Module Family 6 (CBM6), Fibrobacter succinogenes S85 Xyn10D-like; appended mainly to glycoside hydrolase (GH) family 5 and GH43 domains; Region: CBM6_FsXyn10D-like; cd09838
762903008192	putative metal binding site [ion binding]; other site
762903008193	MG2 domain; Region: A2M_N; pfam01835
762903008194	Alpha-2-macroglobulin family; Region: A2M; pfam00207
762903008195	DNA topoisomerase III; Provisional; Region: PRK07726
762903008196	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
762903008197	active site
762903008198	putative interdomain interaction site [polypeptide binding]; other site
762903008199	putative metal-binding site [ion binding]; other site
762903008200	putative nucleotide binding site [chemical binding]; other site
762903008201	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
762903008202	domain I; other site
762903008203	DNA binding groove [nucleotide binding]
762903008204	phosphate binding site [ion binding]; other site
762903008205	domain II; other site
762903008206	domain III; other site
762903008207	nucleotide binding site [chemical binding]; other site
762903008208	catalytic site [active]
762903008209	domain IV; other site
762903008210	GldH lipoprotein; Region: GldH_lipo; pfam14109
762903008211	PSP1 C-terminal conserved region; Region: PSP1; cl00770
762903008212	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
762903008213	DNA polymerase III subunit delta'; Validated; Region: PRK08485
762903008214	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
762903008215	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
762903008216	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903008217	Coenzyme A binding pocket [chemical binding]; other site
762903008218	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903008219	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
762903008220	putative ADP-binding pocket [chemical binding]; other site
762903008221	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
762903008222	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
762903008223	dimer interface [polypeptide binding]; other site
762903008224	ssDNA binding site [nucleotide binding]; other site
762903008225	tetramer (dimer of dimers) interface [polypeptide binding]; other site
762903008226	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
762903008227	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903008228	S-adenosylmethionine binding site [chemical binding]; other site
762903008229	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
762903008230	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
762903008231	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
762903008232	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008233	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
762903008234	signal recognition particle protein; Provisional; Region: PRK10867
762903008235	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
762903008236	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
762903008237	P loop; other site
762903008238	GTP binding site [chemical binding]; other site
762903008239	Signal peptide binding domain; Region: SRP_SPB; pfam02978
762903008240	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903008241	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903008242	DNA binding residues [nucleotide binding]
762903008243	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
762903008244	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903008245	FecR protein; Region: FecR; pfam04773
762903008246	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903008247	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903008248	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008249	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903008250	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903008251	SusD family; Region: SusD; pfam07980
762903008252	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
762903008253	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
762903008254	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
762903008255	active site
762903008256	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
762903008257	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
762903008258	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
762903008259	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008260	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903008261	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
762903008262	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
762903008263	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
762903008264	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
762903008265	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
762903008266	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
762903008267	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
762903008268	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
762903008269	Coenzyme A binding pocket [chemical binding]; other site
762903008270	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
762903008271	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
762903008272	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
762903008273	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
762903008274	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903008275	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903008276	dimer interface [polypeptide binding]; other site
762903008277	phosphorylation site [posttranslational modification]
762903008278	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903008279	ATP binding site [chemical binding]; other site
762903008280	Mg2+ binding site [ion binding]; other site
762903008281	G-X-G motif; other site
762903008282	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903008283	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903008284	active site
762903008285	phosphorylation site [posttranslational modification]
762903008286	intermolecular recognition site; other site
762903008287	dimerization interface [polypeptide binding]; other site
762903008288	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
762903008289	DNA binding site [nucleotide binding]
762903008290	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
762903008291	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
762903008292	E3 interaction surface; other site
762903008293	lipoyl attachment site [posttranslational modification]; other site
762903008294	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
762903008295	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
762903008296	E3 interaction surface; other site
762903008297	lipoyl attachment site [posttranslational modification]; other site
762903008298	e3 binding domain; Region: E3_binding; pfam02817
762903008299	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
762903008300	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
762903008301	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
762903008302	tetramer interface [polypeptide binding]; other site
762903008303	TPP-binding site [chemical binding]; other site
762903008304	heterodimer interface [polypeptide binding]; other site
762903008305	phosphorylation loop region [posttranslational modification]
762903008306	NlpC/P60 family; Region: NLPC_P60; pfam00877
762903008307	M28 Zn-Peptidase IAP aminopeptidase may contain PA domain insert; Region: M28_like_5; cd08021
762903008308	Peptidase family M28; Region: Peptidase_M28; pfam04389
762903008309	metal binding site [ion binding]; metal-binding site
762903008310	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
762903008311	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903008312	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903008313	Predicted membrane protein [Function unknown]; Region: COG2259
762903008314	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903008315	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
762903008316	nucleophilic elbow; other site
762903008317	catalytic triad; other site
762903008318	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
762903008319	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
762903008320	dimer interface [polypeptide binding]; other site
762903008321	ssDNA binding site [nucleotide binding]; other site
762903008322	tetramer (dimer of dimers) interface [polypeptide binding]; other site
762903008323	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
762903008324	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
762903008325	minor groove reading motif; other site
762903008326	helix-hairpin-helix signature motif; other site
762903008327	substrate binding pocket [chemical binding]; other site
762903008328	active site
762903008329	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
762903008330	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
762903008331	DNA binding and oxoG recognition site [nucleotide binding]
762903008332	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
762903008333	IHF - DNA interface [nucleotide binding]; other site
762903008334	IHF dimer interface [polypeptide binding]; other site
762903008335	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008336	TPR motif; other site
762903008337	TPR repeat; Region: TPR_11; pfam13414
762903008338	binding surface
762903008339	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
762903008340	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
762903008341	homodimer interface [polypeptide binding]; other site
762903008342	oligonucleotide binding site [chemical binding]; other site
762903008343	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
762903008344	putative transporter; Provisional; Region: PRK10504
762903008345	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903008346	putative substrate translocation pore; other site
762903008347	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
762903008348	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
762903008349	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
762903008350	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
762903008351	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
762903008352	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
762903008353	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
762903008354	ATP-grasp domain; Region: ATP-grasp_4; cl17255
762903008355	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
762903008356	active site
762903008357	catalytic residues [active]
762903008358	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008359	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903008360	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903008361	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
762903008362	active site
762903008363	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
762903008364	putative active site [active]
762903008365	putative catalytic site [active]
762903008366	putative DNA binding site [nucleotide binding]; other site
762903008367	putative phosphate binding site [ion binding]; other site
762903008368	metal binding site A [ion binding]; metal-binding site
762903008369	putative AP binding site [nucleotide binding]; other site
762903008370	putative metal binding site B [ion binding]; other site
762903008371	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903008372	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008373	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903008374	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903008375	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
762903008376	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903008377	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
762903008378	dimer interface [polypeptide binding]; other site
762903008379	catalytic triad [active]
762903008380	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
762903008381	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
762903008382	active site
762903008383	HIGH motif; other site
762903008384	KMSKS motif; other site
762903008385	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
762903008386	tRNA binding surface [nucleotide binding]; other site
762903008387	anticodon binding site; other site
762903008388	The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human...; Region: tRNA_bindingDomain; cl00320
762903008389	putative tRNA-binding site [nucleotide binding]; other site
762903008390	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
762903008391	GIY-YIG motif/motif A; other site
762903008392	putative active site [active]
762903008393	putative metal binding site [ion binding]; other site
762903008394	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
762903008395	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
762903008396	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
762903008397	Glycerol-1-phosphate dehydrogenase (G1PDH) catalyzes the reversible reduction of dihydroxyacetone phosphate (DHAP) to glycerol-1-phosphate (G1P) in an NADH-dependent manner; Region: G1PDH; cd08175
762903008398	active site
762903008399	metal binding site [ion binding]; metal-binding site
762903008400	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
762903008401	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
762903008402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903008403	putative substrate translocation pore; other site
762903008404	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
762903008405	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903008406	active site
762903008407	motif I; other site
762903008408	motif II; other site
762903008409	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903008410	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
762903008411	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
762903008412	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
762903008413	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
762903008414	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
762903008415	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
762903008416	HlyD family secretion protein; Region: HlyD_3; pfam13437
762903008417	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
762903008418	Domain of unknown function (DUF4258); Region: DUF4258; pfam14076
762903008419	Two component regulator propeller; Region: Reg_prop; pfam07494
762903008420	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903008421	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903008422	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903008423	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903008424	dimer interface [polypeptide binding]; other site
762903008425	phosphorylation site [posttranslational modification]
762903008426	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903008427	ATP binding site [chemical binding]; other site
762903008428	Mg2+ binding site [ion binding]; other site
762903008429	G-X-G motif; other site
762903008430	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903008431	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903008432	active site
762903008433	phosphorylation site [posttranslational modification]
762903008434	intermolecular recognition site; other site
762903008435	dimerization interface [polypeptide binding]; other site
762903008436	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903008437	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903008438	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008439	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903008440	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903008441	SusE outer membrane protein; Region: SusE; pfam14292
762903008442	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cl17376
762903008443	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cl17376
762903008444	starch binding site [chemical binding]; other site
762903008445	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; pfam07745
762903008446	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903008447	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903008448	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903008449	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
762903008450	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
762903008451	ribosome recycling factor; Reviewed; Region: frr; PRK00083
762903008452	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
762903008453	hinge region; other site
762903008454	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
762903008455	putative nucleotide binding site [chemical binding]; other site
762903008456	uridine monophosphate binding site [chemical binding]; other site
762903008457	homohexameric interface [polypeptide binding]; other site
762903008458	elongation factor Ts; Provisional; Region: tsf; PRK09377
762903008459	UBA/TS-N domain; Region: UBA; pfam00627
762903008460	Elongation factor TS; Region: EF_TS; pfam00889
762903008461	Elongation factor TS; Region: EF_TS; pfam00889
762903008462	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
762903008463	rRNA interaction site [nucleotide binding]; other site
762903008464	S8 interaction site; other site
762903008465	putative laminin-1 binding site; other site
762903008466	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
762903008467	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
762903008468	23S rRNA interface [nucleotide binding]; other site
762903008469	L3 interface [polypeptide binding]; other site
762903008470	glycerol kinase; Provisional; Region: glpK; PRK00047
762903008471	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
762903008472	N- and C-terminal domain interface [polypeptide binding]; other site
762903008473	active site
762903008474	MgATP binding site [chemical binding]; other site
762903008475	catalytic site [active]
762903008476	metal binding site [ion binding]; metal-binding site
762903008477	glycerol binding site [chemical binding]; other site
762903008478	homotetramer interface [polypeptide binding]; other site
762903008479	homodimer interface [polypeptide binding]; other site
762903008480	FBP binding site [chemical binding]; other site
762903008481	protein IIAGlc interface [polypeptide binding]; other site
762903008482	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
762903008483	amphipathic channel; other site
762903008484	Asn-Pro-Ala signature motifs; other site
762903008485	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903008486	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903008487	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903008488	DNA binding residues [nucleotide binding]
762903008489	FecR protein; Region: FecR; pfam04773
762903008490	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903008491	Secretin and TonB N terminus short domain; Region: STN; pfam07660
762903008492	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008493	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903008494	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903008495	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903008496	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
762903008497	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903008498	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903008499	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903008500	active site
762903008501	metal binding site [ion binding]; metal-binding site
762903008502	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
762903008503	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903008504	active site
762903008505	metal binding site [ion binding]; metal-binding site
762903008506	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903008507	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903008508	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903008509	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
762903008510	Cytochrome c; Region: Cytochrom_C; cl11414
762903008511	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
762903008512	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
762903008513	beta-alpha-beta structure motif; other site
762903008514	NAD binding pocket [chemical binding]; other site
762903008515	argininosuccinate synthase; Provisional; Region: PRK13820
762903008516	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
762903008517	Ligand Binding Site [chemical binding]; other site
762903008518	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
762903008519	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
762903008520	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
762903008521	four helix bundle protein; Region: TIGR02436
762903008522	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
762903008523	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
762903008524	inhibitor-cofactor binding pocket; inhibition site
762903008525	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903008526	catalytic residue [active]
762903008527	N-acetylornithine carbamoyltransferase; Reviewed; Region: PRK04523
762903008528	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
762903008529	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
762903008530	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
762903008531	nucleotide binding site [chemical binding]; other site
762903008532	N-acetyl-L-glutamate binding site [chemical binding]; other site
762903008533	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
762903008534	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
762903008535	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
762903008536	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like5; cd05651
762903008537	metal binding site [ion binding]; metal-binding site
762903008538	dimer interface [polypeptide binding]; other site
762903008539	four helix bundle protein; Region: TIGR02436
762903008540	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
762903008541	argininosuccinate lyase; Provisional; Region: PRK00855
762903008542	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
762903008543	active sites [active]
762903008544	tetramer interface [polypeptide binding]; other site
762903008545	aspartate aminotransferase; Provisional; Region: PRK05764
762903008546	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
762903008547	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903008548	homodimer interface [polypeptide binding]; other site
762903008549	catalytic residue [active]
762903008550	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
762903008551	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
762903008552	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903008553	active site
762903008554	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
762903008555	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
762903008556	inhibitor-cofactor binding pocket; inhibition site
762903008557	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903008558	catalytic residue [active]
762903008559	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
762903008560	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
762903008561	putative trimer interface [polypeptide binding]; other site
762903008562	putative CoA binding site [chemical binding]; other site
762903008563	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903008564	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
762903008565	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
762903008566	metal-binding site
762903008567	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
762903008568	excinuclease ABC subunit B; Provisional; Region: PRK05298
762903008569	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903008570	ATP binding site [chemical binding]; other site
762903008571	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903008572	nucleotide binding region [chemical binding]; other site
762903008573	ATP-binding site [chemical binding]; other site
762903008574	Ultra-violet resistance protein B; Region: UvrB; pfam12344
762903008575	UvrB/uvrC motif; Region: UVR; pfam02151
762903008576	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u7; cd10931
762903008577	putative active site [active]
762903008578	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
762903008579	active site
762903008580	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
762903008581	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903008582	motif II; other site
762903008583	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
762903008584	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
762903008585	putative active site [active]
762903008586	putative metal binding site [ion binding]; other site
762903008587	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
762903008588	Type III pantothenate kinase; Region: Pan_kinase; cl17198
762903008589	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
762903008590	SurA N-terminal domain; Region: SurA_N_3; cl07813
762903008591	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
762903008592	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
762903008593	Protein of unknown function (DUF2480); Region: DUF2480; pfam10652
762903008594	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
762903008595	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
762903008596	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
762903008597	inhibitor-cofactor binding pocket; inhibition site
762903008598	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903008599	catalytic residue [active]
762903008600	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
762903008601	putative trimer interface [polypeptide binding]; other site
762903008602	putative CoA binding site [chemical binding]; other site
762903008603	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
762903008604	putative trimer interface [polypeptide binding]; other site
762903008605	putative active site [active]
762903008606	putative substrate binding site [chemical binding]; other site
762903008607	putative CoA binding site [chemical binding]; other site
762903008608	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
762903008609	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
762903008610	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
762903008611	substrate binding site; other site
762903008612	tetramer interface; other site
762903008613	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
762903008614	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
762903008615	NADP-binding site; other site
762903008616	homotetramer interface [polypeptide binding]; other site
762903008617	substrate binding site [chemical binding]; other site
762903008618	homodimer interface [polypeptide binding]; other site
762903008619	active site
762903008620	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
762903008621	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
762903008622	SLBB domain; Region: SLBB; pfam10531
762903008623	SLBB domain; Region: SLBB; pfam10531
762903008624	SLBB domain; Region: SLBB; pfam10531
762903008625	SLBB domain; Region: SLBB; pfam10531
762903008626	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
762903008627	SLBB domain; Region: SLBB; pfam10531
762903008628	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
762903008629	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
762903008630	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
762903008631	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
762903008632	WxcM-like, C-terminal; Region: FdtA; pfam05523
762903008633	WxcM-like, C-terminal; Region: FdtA; pfam05523
762903008634	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
762903008635	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
762903008636	putative trimer interface [polypeptide binding]; other site
762903008637	putative active site [active]
762903008638	putative substrate binding site [chemical binding]; other site
762903008639	putative CoA binding site [chemical binding]; other site
762903008640	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
762903008641	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
762903008642	inhibitor-cofactor binding pocket; inhibition site
762903008643	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903008644	catalytic residue [active]
762903008645	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
762903008646	putative trimer interface [polypeptide binding]; other site
762903008647	putative CoA binding site [chemical binding]; other site
762903008648	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
762903008649	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
762903008650	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
762903008651	active site
762903008652	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
762903008653	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903008654	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
762903008655	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903008656	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
762903008657	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
762903008658	Probable Catalytic site; other site
762903008659	metal-binding site
762903008660	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
762903008661	Divergent AAA domain; Region: AAA_4; pfam04326
762903008662	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
762903008663	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903008664	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
762903008665	NAD(P) binding site [chemical binding]; other site
762903008666	active site
762903008667	Helix-turn-helix domain; Region: HTH_17; cl17695
762903008668	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
762903008669	Transposase; Region: DEDD_Tnp_IS110; pfam01548
762903008670	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
762903008671	TIGR02594 family protein; Region: TIGR02594
762903008672	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
762903008673	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
762903008674	active site
762903008675	HIGH motif; other site
762903008676	nucleotide binding site [chemical binding]; other site
762903008677	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
762903008678	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
762903008679	Mg++ binding site [ion binding]; other site
762903008680	putative catalytic motif [active]
762903008681	putative substrate binding site [chemical binding]; other site
762903008682	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
762903008683	active site
762903008684	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
762903008685	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
762903008686	NAD(P) binding site [chemical binding]; other site
762903008687	homodimer interface [polypeptide binding]; other site
762903008688	substrate binding site [chemical binding]; other site
762903008689	active site
762903008690	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
762903008691	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
762903008692	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
762903008693	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
762903008694	TPP-binding site; other site
762903008695	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
762903008696	PYR/PP interface [polypeptide binding]; other site
762903008697	dimer interface [polypeptide binding]; other site
762903008698	TPP binding site [chemical binding]; other site
762903008699	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
762903008700	ScpA/B protein; Region: ScpA_ScpB; cl00598
762903008701	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903008702	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903008703	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903008704	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
762903008705	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
762903008706	dimer interface [polypeptide binding]; other site
762903008707	active site
762903008708	glycine-pyridoxal phosphate binding site [chemical binding]; other site
762903008709	folate binding site [chemical binding]; other site
762903008710	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903008711	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903008712	active site
762903008713	phosphorylation site [posttranslational modification]
762903008714	intermolecular recognition site; other site
762903008715	dimerization interface [polypeptide binding]; other site
762903008716	Right handed beta helix region; Region: Beta_helix; pfam13229
762903008717	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
762903008718	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
762903008719	active site
762903008720	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
762903008721	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903008722	FeS/SAM binding site; other site
762903008723	chlorohydrolase; Provisional; Region: PRK08418
762903008724	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
762903008725	active site
762903008726	Acylphosphatases [Energy production and conversion]; Region: AcyP; COG1254
762903008727	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
762903008728	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
762903008729	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
762903008730	trimer interface [polypeptide binding]; other site
762903008731	active site
762903008732	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008733	binding surface
762903008734	TPR motif; other site
762903008735	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008736	binding surface
762903008737	TPR motif; other site
762903008738	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008739	binding surface
762903008740	TPR motif; other site
762903008741	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903008742	TPR repeat; Region: TPR_11; pfam13414
762903008743	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
762903008744	binding surface
762903008745	TPR motif; other site
762903008746	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
762903008747	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
762903008748	Peptidase family M23; Region: Peptidase_M23; pfam01551
762903008749	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
762903008750	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
762903008751	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
762903008752	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
762903008753	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
762903008754	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
762903008755	N-acetyl-D-glucosamine binding site [chemical binding]; other site
762903008756	catalytic residue [active]
762903008757	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
762903008758	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
762903008759	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
762903008760	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
762903008761	RuvA N terminal domain; Region: RuvA_N; pfam01330
762903008762	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
762903008763	cell surface protein SprA; Region: surface_SprA; TIGR04189
762903008764	Motility related/secretion protein; Region: SprA_N; pfam14349
762903008765	Motility related/secretion protein; Region: SprA_N; pfam14349
762903008766	Motility related/secretion protein; Region: SprA_N; pfam14349
762903008767	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
762903008768	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
762903008769	lipoyl attachment site [posttranslational modification]; other site
762903008770	FeoA domain; Region: FeoA; pfam04023
762903008771	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
762903008772	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
762903008773	G1 box; other site
762903008774	GTP/Mg2+ binding site [chemical binding]; other site
762903008775	Switch I region; other site
762903008776	G2 box; other site
762903008777	G3 box; other site
762903008778	Switch II region; other site
762903008779	G4 box; other site
762903008780	G5 box; other site
762903008781	Nucleoside recognition; Region: Gate; pfam07670
762903008782	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
762903008783	Nucleoside recognition; Region: Gate; pfam07670
762903008784	SprT homologues; Region: SprT; cl01182
762903008785	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
762903008786	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
762903008787	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
762903008788	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903008789	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903008790	DNA binding site [nucleotide binding]
762903008791	domain linker motif; other site
762903008792	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903008793	ligand binding site [chemical binding]; other site
762903008794	dimerization interface [polypeptide binding]; other site
762903008795	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
762903008796	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
762903008797	dimer interface [polypeptide binding]; other site
762903008798	motif 1; other site
762903008799	active site
762903008800	motif 2; other site
762903008801	motif 3; other site
762903008802	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
762903008803	anticodon binding site; other site
762903008804	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
762903008805	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
762903008806	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
762903008807	Low molecular weight phosphatase family; Region: LMWPc; cd00115
762903008808	active site
762903008809	fumarate hydratase; Reviewed; Region: fumC; PRK00485
762903008810	Class II fumarases; Region: Fumarase_classII; cd01362
762903008811	active site
762903008812	tetramer interface [polypeptide binding]; other site
762903008813	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
762903008814	Beta-lactamase; Region: Beta-lactamase; pfam00144
762903008815	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; cl00494
762903008816	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
762903008817	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
762903008818	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
762903008819	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
762903008820	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
762903008821	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
762903008822	Walker A/P-loop; other site
762903008823	ATP binding site [chemical binding]; other site
762903008824	Q-loop/lid; other site
762903008825	ABC transporter signature motif; other site
762903008826	Walker B; other site
762903008827	D-loop; other site
762903008828	H-loop/switch region; other site
762903008829	Predicted membrane protein [Function unknown]; Region: COG1470
762903008830	NPCBM-associated, NEW3 domain of alpha-galactosidase; Region: NPCBM_assoc; pfam10633
762903008831	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
762903008832	nucleotide binding site/active site [active]
762903008833	HIT family signature motif; other site
762903008834	catalytic residue [active]
762903008835	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
762903008836	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
762903008837	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
762903008838	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
762903008839	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
762903008840	NAD binding site [chemical binding]; other site
762903008841	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
762903008842	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903008843	S-adenosylmethionine binding site [chemical binding]; other site
762903008844	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
762903008845	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
762903008846	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
762903008847	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
762903008848	putative phosphate acyltransferase; Provisional; Region: PRK05331
762903008849	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
762903008850	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
762903008851	dimer interface [polypeptide binding]; other site
762903008852	active site
762903008853	CoA binding pocket [chemical binding]; other site
762903008854	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
762903008855	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
762903008856	carboxyltransferase (CT) interaction site; other site
762903008857	biotinylation site [posttranslational modification]; other site
762903008858	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
762903008859	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
762903008860	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
762903008861	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
762903008862	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
762903008863	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
762903008864	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
762903008865	Putative zinc ribbon domain; Region: DUF164; pfam02591
762903008866	Uncharacterized conserved protein [Function unknown]; Region: COG0327
762903008867	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
762903008868	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
762903008869	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
762903008870	TM2 domain; Region: TM2; cl00984
762903008871	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
762903008872	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
762903008873	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
762903008874	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
762903008875	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
762903008876	ATP binding site [chemical binding]; other site
762903008877	putative Mg++ binding site [ion binding]; other site
762903008878	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
762903008879	nucleotide binding region [chemical binding]; other site
762903008880	ATP-binding site [chemical binding]; other site
762903008881	TRCF domain; Region: TRCF; pfam03461
762903008882	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
762903008883	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
762903008884	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
762903008885	Interdomain contacts; other site
762903008886	Cytokine receptor motif; other site
762903008887	putative oxidoreductase; Provisional; Region: PRK11579
762903008888	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903008889	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903008890	Glyco_18 domain; Region: Glyco_18; smart00636
762903008891	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
762903008892	active site
762903008893	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903008894	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903008895	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903008896	DNA binding residues [nucleotide binding]
762903008897	FecR protein; Region: FecR; pfam04773
762903008898	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903008899	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903008900	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903008901	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903008902	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903008903	SusD family; Region: SusD; pfam07980
762903008904	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903008905	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903008906	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903008907	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903008908	SusD family; Region: SusD; pfam07980
762903008909	Trehalose utilisation; Region: ThuA; pfam06283
762903008910	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
762903008911	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
762903008912	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
762903008913	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
762903008914	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
762903008915	inhibitor-cofactor binding pocket; inhibition site
762903008916	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903008917	catalytic residue [active]
762903008918	biotin synthase; Region: bioB; TIGR00433
762903008919	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903008920	FeS/SAM binding site; other site
762903008921	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
762903008922	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
762903008923	AAA domain; Region: AAA_26; pfam13500
762903008924	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
762903008925	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
762903008926	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
762903008927	catalytic residue [active]
762903008928	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
762903008929	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
762903008930	DNA-binding site [nucleotide binding]; DNA binding site
762903008931	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
762903008932	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903008933	homodimer interface [polypeptide binding]; other site
762903008934	catalytic residue [active]
762903008935	GTPase Era; Reviewed; Region: era; PRK00089
762903008936	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
762903008937	G1 box; other site
762903008938	GTP/Mg2+ binding site [chemical binding]; other site
762903008939	Switch I region; other site
762903008940	G2 box; other site
762903008941	Switch II region; other site
762903008942	G3 box; other site
762903008943	G4 box; other site
762903008944	G5 box; other site
762903008945	KH domain; Region: KH_2; pfam07650
762903008946	GTP-binding protein Der; Reviewed; Region: PRK00093
762903008947	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
762903008948	G1 box; other site
762903008949	GTP/Mg2+ binding site [chemical binding]; other site
762903008950	Switch I region; other site
762903008951	G2 box; other site
762903008952	Switch II region; other site
762903008953	G3 box; other site
762903008954	G4 box; other site
762903008955	G5 box; other site
762903008956	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
762903008957	G1 box; other site
762903008958	GTP/Mg2+ binding site [chemical binding]; other site
762903008959	Switch I region; other site
762903008960	G2 box; other site
762903008961	G3 box; other site
762903008962	Switch II region; other site
762903008963	G4 box; other site
762903008964	G5 box; other site
762903008965	Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) and related proteins; solute binding domain; Region: SLC5sbd_vSGLT; cd10325
762903008966	putative transporter; Provisional; Region: PRK10484
762903008967	Na binding site [ion binding]; other site
762903008968	substrate binding site [chemical binding]; other site
762903008969	xylose isomerase; Provisional; Region: PRK05474
762903008970	xylose isomerase; Region: xylose_isom_A; TIGR02630
762903008971	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
762903008972	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
762903008973	nucleotide binding site [chemical binding]; other site
762903008974	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903008975	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903008976	DNA binding site [nucleotide binding]
762903008977	domain linker motif; other site
762903008978	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903008979	dimerization interface [polypeptide binding]; other site
762903008980	ligand binding site [chemical binding]; other site
762903008981	Response regulator receiver domain; Region: Response_reg; pfam00072
762903008982	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903008983	active site
762903008984	phosphorylation site [posttranslational modification]
762903008985	intermolecular recognition site; other site
762903008986	dimerization interface [polypeptide binding]; other site
762903008987	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903008988	Response regulator receiver domain; Region: Response_reg; pfam00072
762903008989	active site
762903008990	phosphorylation site [posttranslational modification]
762903008991	intermolecular recognition site; other site
762903008992	dimerization interface [polypeptide binding]; other site
762903008993	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903008994	active site
762903008995	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903008996	phosphorylation site [posttranslational modification]
762903008997	intermolecular recognition site; other site
762903008998	dimerization interface [polypeptide binding]; other site
762903008999	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903009000	dimer interface [polypeptide binding]; other site
762903009001	phosphorylation site [posttranslational modification]
762903009002	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903009003	ATP binding site [chemical binding]; other site
762903009004	Mg2+ binding site [ion binding]; other site
762903009005	G-X-G motif; other site
762903009006	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
762903009007	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
762903009008	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903009009	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903009010	dimer interface [polypeptide binding]; other site
762903009011	phosphorylation site [posttranslational modification]
762903009012	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903009013	ATP binding site [chemical binding]; other site
762903009014	Mg2+ binding site [ion binding]; other site
762903009015	G-X-G motif; other site
762903009016	hypothetical protein; Provisional; Region: PRK07877
762903009017	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
762903009018	substrate interface [chemical binding]; other site
762903009019	ATP binding site [chemical binding]; other site
762903009020	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
762903009021	dimer interface [polypeptide binding]; other site
762903009022	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009023	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009024	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009025	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009026	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903009027	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903009028	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
762903009029	Interdomain contacts; other site
762903009030	Cytokine receptor motif; other site
762903009031	Right handed beta helix region; Region: Beta_helix; pfam13229
762903009032	Pectate lyase; Region: Pec_lyase_C; cl01593
762903009033	Pectate lyase; Region: Pec_lyase_C; cl01593
762903009034	Pectate lyase [Carbohydrate transport and metabolism]; Region: PelB; COG3866
762903009035	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
762903009036	active site
762903009037	catalytic triad [active]
762903009038	Pectinesterase; Region: Pectinesterase; pfam01095
762903009039	putative pectinesterase; Region: PLN02432; cl01911
762903009040	The C-terminal domain of uncharacterized bacterial proteins; Region: Bvu_2165_C_like; cd12843
762903009041	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903009042	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903009043	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903009044	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903009045	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903009046	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903009047	dimer interface [polypeptide binding]; other site
762903009048	phosphorylation site [posttranslational modification]
762903009049	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903009050	ATP binding site [chemical binding]; other site
762903009051	Mg2+ binding site [ion binding]; other site
762903009052	G-X-G motif; other site
762903009053	Response regulator receiver domain; Region: Response_reg; pfam00072
762903009054	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903009055	active site
762903009056	phosphorylation site [posttranslational modification]
762903009057	intermolecular recognition site; other site
762903009058	dimerization interface [polypeptide binding]; other site
762903009059	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
762903009060	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
762903009061	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_2; cd09001
762903009062	active site
762903009063	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903009064	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903009065	putative pectinesterase; Region: PLN02432; cl01911
762903009066	Pectinesterase; Region: Pectinesterase; pfam01095
762903009067	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009068	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903009069	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
762903009070	active site
762903009071	catalytic triad [active]
762903009072	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
762903009073	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
762903009074	substrate binding pocket [chemical binding]; other site
762903009075	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903009076	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
762903009077	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009078	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009079	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009080	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903009081	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903009082	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903009083	SusD family; Region: SusD; pfam07980
762903009084	Domain of unknown function (DUF4374); Region: DUF4374; pfam14298
762903009085	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903009086	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009087	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
762903009088	Domain of unknown function (DUF4198); Region: DUF4198; pfam10670
762903009089	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
762903009090	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
762903009091	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
762903009092	Polysaccharide biosynthesis protein; Region: Polysacc_synt; cl10513
762903009093	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
762903009094	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
762903009095	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
762903009096	RNA/DNA hybrid binding site [nucleotide binding]; other site
762903009097	active site
762903009098	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
762903009099	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
762903009100	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
762903009101	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
762903009102	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
762903009103	2-phosphosulpholactate phosphatase; Region: 2-ph_phosp; pfam04029
762903009104	Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Region: COG2045
762903009105	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
762903009106	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
762903009107	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
762903009108	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
762903009109	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
762903009110	homodimer interface [polypeptide binding]; other site
762903009111	metal binding site [ion binding]; metal-binding site
762903009112	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903009113	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903009114	active site
762903009115	metal binding site [ion binding]; metal-binding site
762903009116	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
762903009117	putative active site [active]
762903009118	dimerization interface [polypeptide binding]; other site
762903009119	putative tRNAtyr binding site [nucleotide binding]; other site
762903009120	GTPase RsgA; Reviewed; Region: PRK00098
762903009121	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
762903009122	RNA binding site [nucleotide binding]; other site
762903009123	homodimer interface [polypeptide binding]; other site
762903009124	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
762903009125	GTPase/Zn-binding domain interface [polypeptide binding]; other site
762903009126	GTP/Mg2+ binding site [chemical binding]; other site
762903009127	G4 box; other site
762903009128	G5 box; other site
762903009129	G1 box; other site
762903009130	Switch I region; other site
762903009131	G2 box; other site
762903009132	G3 box; other site
762903009133	Switch II region; other site
762903009134	ORF6N domain; Region: ORF6N; pfam10543
762903009135	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
762903009136	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
762903009137	putative catalytic residues [active]
762903009138	nucleotide binding site [chemical binding]; other site
762903009139	aspartate binding site [chemical binding]; other site
762903009140	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
762903009141	dimer interface [polypeptide binding]; other site
762903009142	putative threonine allosteric regulatory site; other site
762903009143	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
762903009144	putative threonine allosteric regulatory site; other site
762903009145	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
762903009146	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
762903009147	homoserine kinase; Provisional; Region: PRK01212
762903009148	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
762903009149	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
762903009150	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
762903009151	active site
762903009152	NTP binding site [chemical binding]; other site
762903009153	metal binding triad [ion binding]; metal-binding site
762903009154	antibiotic binding site [chemical binding]; other site
762903009155	Uncharacterized conserved protein [Function unknown]; Region: COG2361
762903009156	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
762903009157	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
762903009158	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903009159	catalytic residue [active]
762903009160	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009161	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
762903009162	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903009163	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903009164	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903009165	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903009166	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903009167	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903009168	Beta galactosidase small chain; Region: Bgal_small_N; cl03787
762903009169	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903009170	Heparinase II/III-like protein; Region: Hepar_II_III; cl15421
762903009171	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009172	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
762903009173	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009174	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009175	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903009176	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903009177	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903009178	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
762903009179	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903009180	active site
762903009181	phosphorylation site [posttranslational modification]
762903009182	intermolecular recognition site; other site
762903009183	dimerization interface [polypeptide binding]; other site
762903009184	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903009185	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903009186	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903009187	Sulfatase; Region: Sulfatase; pfam00884
762903009188	Sulfatase; Region: Sulfatase; cl17466
762903009189	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903009190	Protein of unknown function (DUF3050); Region: DUF3050; pfam11251
762903009191	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
762903009192	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
762903009193	putative ligand binding site [chemical binding]; other site
762903009194	putative NAD binding site [chemical binding]; other site
762903009195	catalytic site [active]
762903009196	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
762903009197	FAD binding site [chemical binding]; other site
762903009198	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
762903009199	four helix bundle protein; Region: TIGR02436
762903009200	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
762903009201	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
762903009202	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
762903009203	substrate binding pocket [chemical binding]; other site
762903009204	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
762903009205	B12 binding site [chemical binding]; other site
762903009206	cobalt ligand [ion binding]; other site
762903009207	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
762903009208	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009209	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903009210	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903009211	dimer interface [polypeptide binding]; other site
762903009212	phosphorylation site [posttranslational modification]
762903009213	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903009214	ATP binding site [chemical binding]; other site
762903009215	Mg2+ binding site [ion binding]; other site
762903009216	G-X-G motif; other site
762903009217	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903009218	Response regulator receiver domain; Region: Response_reg; pfam00072
762903009219	active site
762903009220	phosphorylation site [posttranslational modification]
762903009221	intermolecular recognition site; other site
762903009222	dimerization interface [polypeptide binding]; other site
762903009223	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
762903009224	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903009225	active site
762903009226	phosphorylation site [posttranslational modification]
762903009227	intermolecular recognition site; other site
762903009228	dimerization interface [polypeptide binding]; other site
762903009229	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903009230	Walker A motif; other site
762903009231	ATP binding site [chemical binding]; other site
762903009232	Walker B motif; other site
762903009233	arginine finger; other site
762903009234	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
762903009235	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
762903009236	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
762903009237	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
762903009238	Walker A/P-loop; other site
762903009239	ATP binding site [chemical binding]; other site
762903009240	Q-loop/lid; other site
762903009241	ABC transporter signature motif; other site
762903009242	Walker B; other site
762903009243	D-loop; other site
762903009244	H-loop/switch region; other site
762903009245	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
762903009246	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
762903009247	FtsX-like permease family; Region: FtsX; pfam02687
762903009248	Rdx family; Region: Rdx; cl01407
762903009249	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
762903009250	active site
762903009251	SAM binding site [chemical binding]; other site
762903009252	homodimer interface [polypeptide binding]; other site
762903009253	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
762903009254	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
762903009255	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
762903009256	nudix motif; other site
762903009257	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
762903009258	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
762903009259	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
762903009260	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
762903009261	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
762903009262	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
762903009263	active site
762903009264	catalytic residues [active]
762903009265	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
762903009266	active site
762903009267	catalytic residues [active]
762903009268	Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis]; Region: COG2348
762903009269	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
762903009270	Predicted membrane protein [Function unknown]; Region: COG2323
762903009271	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
762903009272	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
762903009273	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
762903009274	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
762903009275	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
762903009276	Ligand Binding Site [chemical binding]; other site
762903009277	TilS substrate C-terminal domain; Region: TilS_C; smart00977
762903009278	OstA-like protein; Region: OstA_2; pfam13100
762903009279	OstA-like protein; Region: OstA; cl00844
762903009280	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
762903009281	active site
762903009282	dimerization interface [polypeptide binding]; other site
762903009283	SurA N-terminal domain; Region: SurA_N; pfam09312
762903009284	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
762903009285	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
762903009286	MoxR-like ATPases [General function prediction only]; Region: COG0714
762903009287	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903009288	Walker A motif; other site
762903009289	ATP binding site [chemical binding]; other site
762903009290	Walker B motif; other site
762903009291	arginine finger; other site
762903009292	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
762903009293	intracellular protease, PfpI family; Region: PfpI; TIGR01382
762903009294	proposed catalytic triad [active]
762903009295	conserved cys residue [active]
762903009296	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
762903009297	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
762903009298	active site
762903009299	HIGH motif; other site
762903009300	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
762903009301	KMSKS motif; other site
762903009302	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
762903009303	tRNA binding surface [nucleotide binding]; other site
762903009304	anticodon binding site; other site
762903009305	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
762903009306	putative catalytic site [active]
762903009307	putative metal binding site [ion binding]; other site
762903009308	putative phosphate binding site [ion binding]; other site
762903009309	Rhomboid family; Region: Rhomboid; pfam01694
762903009310	Rhomboid family; Region: Rhomboid; pfam01694
762903009311	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
762903009312	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903009313	ATP binding site [chemical binding]; other site
762903009314	Mg2+ binding site [ion binding]; other site
762903009315	G-X-G motif; other site
762903009316	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
762903009317	ATP binding site [chemical binding]; other site
762903009318	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
762903009319	Beta-lactamase; Region: Beta-lactamase; cl17358
762903009320	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
762903009321	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
762903009322	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
762903009323	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
762903009324	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903009325	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
762903009326	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
762903009327	RNA binding surface [nucleotide binding]; other site
762903009328	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
762903009329	active site
762903009330	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
762903009331	N-acetyl-D-glucosamine binding site [chemical binding]; other site
762903009332	catalytic residue [active]
762903009333	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903009334	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
762903009335	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
762903009336	N-terminal plug; other site
762903009337	ligand-binding site [chemical binding]; other site
762903009338	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
762903009339	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
762903009340	active site
762903009341	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
762903009342	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
762903009343	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
762903009344	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
762903009345	Phosphoesterase family; Region: Phosphoesterase; pfam04185
762903009346	Phosphoesterase family; Region: Phosphoesterase; pfam04185
762903009347	Domain of unknown function (DUF756); Region: DUF756; pfam05506
762903009348	Domain of unknown function (DUF756); Region: DUF756; pfam05506
762903009349	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
762903009350	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
762903009351	putative substrate binding site [chemical binding]; other site
762903009352	putative ATP binding site [chemical binding]; other site
762903009353	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
762903009354	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903009355	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903009356	DNA binding residues [nucleotide binding]
762903009357	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
762903009358	FecR protein; Region: FecR; pfam04773
762903009359	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009360	lipoyl synthase; Provisional; Region: PRK05481
762903009361	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
762903009362	FeS/SAM binding site; other site
762903009363	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; pfam02617
762903009364	putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12674
762903009365	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12599
762903009366	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK12651
762903009367	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK12663
762903009368	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
762903009369	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; Region: Oxidored_q2; cl00492
762903009370	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12509
762903009371	putative monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12647
762903009372	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
762903009373	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
762903009374	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
762903009375	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
762903009376	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
762903009377	Protein of unknown function (DUF4080); Region: DUF4080; pfam13311
762903009378	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
762903009379	DNA-binding site [nucleotide binding]; DNA binding site
762903009380	RNA-binding motif; other site
762903009381	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
762903009382	DNA-binding site [nucleotide binding]; DNA binding site
762903009383	RNA-binding motif; other site
762903009384	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
762903009385	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
762903009386	OsmC-like protein; Region: OsmC; cl00767
762903009387	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cl00218
762903009388	EVE domain; Region: EVE; cl00728
762903009389	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
762903009390	active site
762903009391	TatD related DNase; Region: TatD_DNase; pfam01026
762903009392	active site
762903009393	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
762903009394	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
762903009395	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
762903009396	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
762903009397	HerA helicase [Replication, recombination, and repair]; Region: COG0433
762903009398	Domain of unknown function DUF87; Region: DUF87; pfam01935
762903009399	AAA-like domain; Region: AAA_10; pfam12846
762903009400	SIR2-like domain; Region: SIR2_2; pfam13289
762903009401	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
762903009402	non-specific DNA binding site [nucleotide binding]; other site
762903009403	salt bridge; other site
762903009404	sequence-specific DNA binding site [nucleotide binding]; other site
762903009405	VirE N-terminal domain; Region: VirE_N; pfam08800
762903009406	Predicted P-loop ATPase and inactivated derivatives [General function prediction only]; Region: COG5545
762903009407	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
762903009408	Helix-turn-helix domain; Region: HTH_17; pfam12728
762903009409	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
762903009410	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
762903009411	dimer interface [polypeptide binding]; other site
762903009412	active site
762903009413	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903009414	Major Facilitator Superfamily; Region: MFS_1; pfam07690
762903009415	putative substrate translocation pore; other site
762903009416	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903009417	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
762903009418	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
762903009419	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
762903009420	CoenzymeA binding site [chemical binding]; other site
762903009421	subunit interaction site [polypeptide binding]; other site
762903009422	PHB binding site; other site
762903009423	acetyl-CoA C-acetyltransferase; Region: PLN02644
762903009424	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
762903009425	dimer interface [polypeptide binding]; other site
762903009426	active site
762903009427	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
762903009428	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
762903009429	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
762903009430	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
762903009431	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
762903009432	EamA-like transporter family; Region: EamA; pfam00892
762903009433	EamA-like transporter family; Region: EamA; pfam00892
762903009434	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
762903009435	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
762903009436	active site
762903009437	DNA binding site [nucleotide binding]
762903009438	Int/Topo IB signature motif; other site
762903009439	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
762903009440	Tic20-like protein; Region: Tic20; pfam09685
762903009441	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
762903009442	TM2 domain; Region: TM2; pfam05154
762903009443	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
762903009444	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
762903009445	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
762903009446	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
762903009447	putative DNA binding site [nucleotide binding]; other site
762903009448	putative Zn2+ binding site [ion binding]; other site
762903009449	AsnC family; Region: AsnC_trans_reg; pfam01037
762903009450	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
762903009451	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
762903009452	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
762903009453	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
762903009454	RNA binding site [nucleotide binding]; other site
762903009455	Pirin-related protein [General function prediction only]; Region: COG1741
762903009456	Pirin; Region: Pirin; pfam02678
762903009457	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
762903009458	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903009459	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903009460	flexible hinge region; other site
762903009461	leukotriene A-4 hydrolase/aminopeptidase; Region: leuko_A4_hydro; TIGR02411
762903009462	Peptidase M1 family contains leukotriene A4 hydrolase; Region: M1_LTA4H; cd09599
762903009463	active site
762903009464	Zn binding site [ion binding]; other site
762903009465	Leukotriene A4 hydrolase, C-terminal; Region: Leuk-A4-hydro_C; pfam09127
762903009466	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009467	Gram-negative bacterial tonB protein; Region: TonB; cl10048
762903009468	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
762903009469	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
762903009470	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
762903009471	DNA binding residues [nucleotide binding]
762903009472	Protein of unknown function (DUF4197); Region: DUF4197; pfam13852
762903009473	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
762903009474	dimer interface [polypeptide binding]; other site
762903009475	putative tRNA-binding site [nucleotide binding]; other site
762903009476	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
762903009477	nucleoside/Zn binding site; other site
762903009478	dimer interface [polypeptide binding]; other site
762903009479	catalytic motif [active]
762903009480	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
762903009481	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
762903009482	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
762903009483	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
762903009484	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
762903009485	NAD(P) binding site [chemical binding]; other site
762903009486	Response regulator containing CheY-like receiver and SARP domains [Signal transduction mechanisms]; Region: COG3947
762903009487	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
762903009488	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
762903009489	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
762903009490	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
762903009491	nucleotide binding site [chemical binding]; other site
762903009492	L-fucose transporter; Provisional; Region: PRK10133; cl17665
762903009493	glucose/galactose transporter; Region: gluP; TIGR01272
762903009494	L-fucose transporter; Provisional; Region: PRK10133; cl17665
762903009495	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009496	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009497	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009498	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009499	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
762903009500	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903009501	Uncharacterized glycoside hydrolase family 99-like domain; Region: GH99_GH71_like_1; cd11578
762903009502	putative ligand binding site [chemical binding]; other site
762903009503	putative catalytic site [active]
762903009504	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903009505	active site
762903009506	metal binding site [ion binding]; metal-binding site
762903009507	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903009508	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903009509	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903009510	active site
762903009511	metal binding site [ion binding]; metal-binding site
762903009512	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903009513	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
762903009514	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903009515	active site
762903009516	metal binding site [ion binding]; metal-binding site
762903009517	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009518	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009519	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009520	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009521	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
762903009522	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903009523	Uncharacterized glycoside hydrolase family 99-like domain; Region: GH99_GH71_like_1; cd11578
762903009524	putative ligand binding site [chemical binding]; other site
762903009525	putative catalytic site [active]
762903009526	Uncharacterized glycoside hydrolase family 99-like domain; Region: GH99_GH71_like_2; cd11576
762903009527	putative ligand binding site [chemical binding]; other site
762903009528	putative catalytic site [active]
762903009529	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
762903009530	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
762903009531	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
762903009532	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
762903009533	active site
762903009534	metal binding site [ion binding]; metal-binding site
762903009535	Domain of unknown function (DUF4407); Region: DUF4407; pfam14362
762903009536	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
762903009537	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
762903009538	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
762903009539	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
762903009540	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
762903009541	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
762903009542	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903009543	catalytic residues [active]
762903009544	agmatinase; Region: agmatinase; TIGR01230
762903009545	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
762903009546	putative active site [active]
762903009547	putative metal binding site [ion binding]; other site
762903009548	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903009549	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
762903009550	NAD(P) binding site [chemical binding]; other site
762903009551	active site
762903009552	Choloylglycine hydrolase (CGH) is a bile salt-modifying enzyme that hydrolyzes non-peptide carbon-nitrogen bonds in choloylglycine and choloyltaurine, both of which are present in bile.  CGH is present in a number of probiotic microbial organisms that...; Region: Ntn_CGH; cd01902
762903009553	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
762903009554	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
762903009555	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
762903009556	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
762903009557	L-serine binding site [chemical binding]; other site
762903009558	ACT domain interface; other site
762903009559	hypothetical protein; Provisional; Region: PRK11239
762903009560	Protein of unknown function, DUF480; Region: DUF480; pfam04337
762903009561	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
762903009562	PAS fold; Region: PAS_3; pfam08447
762903009563	putative active site [active]
762903009564	heme pocket [chemical binding]; other site
762903009565	Helix-turn-helix domain; Region: HTH_18; pfam12833
762903009566	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903009567	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
762903009568	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
762903009569	homodimer interface [polypeptide binding]; other site
762903009570	substrate-cofactor binding pocket; other site
762903009571	catalytic residue [active]
762903009572	Beta-lactamase; Region: Beta-lactamase; pfam00144
762903009573	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
762903009574	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
762903009575	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
762903009576	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
762903009577	FeS/SAM binding site; other site
762903009578	TRAM domain; Region: TRAM; pfam01938
762903009579	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
762903009580	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
762903009581	Walker A motif; other site
762903009582	ATP binding site [chemical binding]; other site
762903009583	Walker B motif; other site
762903009584	arginine finger; other site
762903009585	Lipopolysaccharide-assembly; Region: LptE; pfam04390
762903009586	Preprotein translocase SecG subunit; Region: SecG; pfam03840
762903009587	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
762903009588	oligomerisation interface [polypeptide binding]; other site
762903009589	mobile loop; other site
762903009590	roof hairpin; other site
762903009591	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
762903009592	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
762903009593	ring oligomerisation interface [polypeptide binding]; other site
762903009594	ATP/Mg binding site [chemical binding]; other site
762903009595	stacking interactions; other site
762903009596	hinge regions; other site
762903009597	MgtC family; Region: MgtC; pfam02308
762903009598	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
762903009599	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
762903009600	active site flap/lid [active]
762903009601	nucleophilic elbow; other site
762903009602	catalytic triad [active]
762903009603	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
762903009604	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
762903009605	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
762903009606	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
762903009607	trimer interface [polypeptide binding]; other site
762903009608	active site
762903009609	MG2 domain; Region: A2M_N; pfam01835
762903009610	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
762903009611	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903009612	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009613	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
762903009614	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
762903009615	substrate binding site [chemical binding]; other site
762903009616	oxyanion hole (OAH) forming residues; other site
762903009617	trimer interface [polypeptide binding]; other site
762903009618	Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR; Region: TER_DECR_SDR_a; cd05369
762903009619	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
762903009620	NAD(P) binding site [chemical binding]; other site
762903009621	substrate binding site [chemical binding]; other site
762903009622	homotetramer interface [polypeptide binding]; other site
762903009623	active site
762903009624	homodimer interface [polypeptide binding]; other site
762903009625	Peptidase family M1; Region: Peptidase_M1; pfam01433
762903009626	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
762903009627	Zn binding site [ion binding]; other site
762903009628	HEAT repeats; Region: HEAT_2; pfam13646
762903009629	Tetratricopeptide repeat; Region: TPR_12; pfam13424
762903009630	bacillithiol system oxidoreductase, YphP/YqiW family; Region: YphP_YqiW; TIGR04191
762903009631	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
762903009632	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
762903009633	homotetramer interface [polypeptide binding]; other site
762903009634	ligand binding site [chemical binding]; other site
762903009635	catalytic site [active]
762903009636	NAD binding site [chemical binding]; other site
762903009637	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_1; cd02432
762903009638	SdpI/YhfL protein family; Region: SdpI; pfam13630
762903009639	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
762903009640	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
762903009641	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
762903009642	catalytic site [active]
762903009643	subunit interface [polypeptide binding]; other site
762903009644	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
762903009645	active site
762903009646	oligomerization interface [polypeptide binding]; other site
762903009647	metal binding site [ion binding]; metal-binding site
762903009648	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
762903009649	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
762903009650	active site
762903009651	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
762903009652	active site
762903009653	nucleophile elbow; other site
762903009654	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
762903009655	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
762903009656	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
762903009657	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903009658	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
762903009659	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
762903009660	G1 box; other site
762903009661	putative GEF interaction site [polypeptide binding]; other site
762903009662	GTP/Mg2+ binding site [chemical binding]; other site
762903009663	Switch I region; other site
762903009664	G2 box; other site
762903009665	G3 box; other site
762903009666	Switch II region; other site
762903009667	G4 box; other site
762903009668	G5 box; other site
762903009669	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
762903009670	pyruvate dehydrogenase; Provisional; Region: PRK06546
762903009671	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
762903009672	PYR/PP interface [polypeptide binding]; other site
762903009673	dimer interface [polypeptide binding]; other site
762903009674	tetramer interface [polypeptide binding]; other site
762903009675	TPP binding site [chemical binding]; other site
762903009676	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
762903009677	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
762903009678	TPP-binding site [chemical binding]; other site
762903009679	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
762903009680	active site
762903009681	multimer interface [polypeptide binding]; other site
762903009682	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
762903009683	DHH family; Region: DHH; pfam01368
762903009684	DHHA1 domain; Region: DHHA1; pfam02272
762903009685	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
762903009686	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
762903009687	active site
762903009688	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
762903009689	active site
762903009690	homodimer interface [polypeptide binding]; other site
762903009691	Domain of unknown function (DUF4260); Region: DUF4260; pfam14079
762903009692	gliding motility-associated lipoprotein GldJ; Region: GldJ_short; TIGR03530
762903009693	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
762903009694	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
762903009695	putative catalytic site [active]
762903009696	putative metal binding site [ion binding]; other site
762903009697	putative phosphate binding site [ion binding]; other site
762903009698	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009699	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009700	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009701	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009702	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903009703	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903009704	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
762903009705	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
762903009706	He_PIG associated, NEW1 domain of bacterial glycohydrolase; Region: He_PIG_assoc; pfam10632
762903009707	Putative Ig domain; Region: He_PIG; pfam05345
762903009708	alpha-galactosidase; Region: PLN02808; cl17638
762903009709	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
762903009710	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
762903009711	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
762903009712	active site
762903009713	catalytic site [active]
762903009714	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009715	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009716	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
762903009717	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903009718	SusD family; Region: SusD; pfam07980
762903009719	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
762903009720	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
762903009721	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903009722	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
762903009723	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
762903009724	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009725	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903009726	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
762903009727	Right handed beta helix region; Region: Beta_helix; pfam13229
762903009728	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009729	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
762903009730	Acyltransferase family; Region: Acyl_transf_3; pfam01757
762903009731	Uncharacterized conserved protein (DUF2249); Region: DUF2249; pfam10006
762903009732	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
762903009733	iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652
762903009734	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
762903009735	Domain of unknown function (DUF1858); Region: DUF1858; cl14817
762903009736	Uncharacterized conserved protein (DUF2249); Region: DUF2249; cl17719
762903009737	Uncharacterized conserved protein (DUF2249); Region: DUF2249; pfam10006
762903009738	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
762903009739	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
762903009740	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
762903009741	iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652
762903009742	Hemerythrin-like domain; Region: Hr-like; cd12108
762903009743	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
762903009744	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903009745	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
762903009746	ligand binding site [chemical binding]; other site
762903009747	flexible hinge region; other site
762903009748	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
762903009749	putative switch regulator; other site
762903009750	non-specific DNA interactions [nucleotide binding]; other site
762903009751	DNA binding site [nucleotide binding]
762903009752	sequence specific DNA binding site [nucleotide binding]; other site
762903009753	putative cAMP binding site [chemical binding]; other site
762903009754	GxxExxY protein; Region: GxxExxY; TIGR04256
762903009755	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
762903009756	heme-binding site [chemical binding]; other site
762903009757	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
762903009758	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
762903009759	Walker A/P-loop; other site
762903009760	ATP binding site [chemical binding]; other site
762903009761	Q-loop/lid; other site
762903009762	ABC transporter signature motif; other site
762903009763	Walker B; other site
762903009764	D-loop; other site
762903009765	H-loop/switch region; other site
762903009766	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
762903009767	NosL; Region: NosL; cl01769
762903009768	nitrous-oxide reductase, Sec-dependent; Region: nitrous_NosZ_Gp; TIGR04246
762903009769	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
762903009770	Cytochrome c; Region: Cytochrom_C; pfam00034
762903009771	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
762903009772	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
762903009773	putative Cl- selectivity filter; other site
762903009774	putative pore gating glutamate residue; other site
762903009775	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
762903009776	Domain of unknown function DUF20; Region: UPF0118; pfam01594
762903009777	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
762903009778	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
762903009779	motif II; other site
762903009780	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
762903009781	dimerization interface [polypeptide binding]; other site
762903009782	putative DNA binding site [nucleotide binding]; other site
762903009783	putative Zn2+ binding site [ion binding]; other site
762903009784	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
762903009785	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
762903009786	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
762903009787	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
762903009788	active site residue [active]
762903009789	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
762903009790	active site residue [active]
762903009791	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
762903009792	active site residue [active]
762903009793	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
762903009794	active site residue [active]
762903009795	Sulphur transport; Region: Sulf_transp; pfam04143
762903009796	Predicted transporter component [General function prediction only]; Region: COG2391
762903009797	Sulphur transport; Region: Sulf_transp; pfam04143
762903009798	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
762903009799	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
762903009800	catalytic residues [active]
762903009801	Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component [Transcription / Signal transduction mechanisms]; Region: MecR1; COG4219
762903009802	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
762903009803	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
762903009804	Penicillinase repressor; Region: Pencillinase_R; pfam03965
762903009805	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
762903009806	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903009807	S-adenosylmethionine binding site [chemical binding]; other site
762903009808	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
762903009809	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
762903009810	active site residue [active]
762903009811	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
762903009812	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
762903009813	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
762903009814	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
762903009815	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
762903009816	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
762903009817	dimer interface [polypeptide binding]; other site
762903009818	motif 1; other site
762903009819	active site
762903009820	motif 2; other site
762903009821	motif 3; other site
762903009822	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
762903009823	iron-sulfur cluster [ion binding]; other site
762903009824	[2Fe-2S] cluster binding site [ion binding]; other site
762903009825	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
762903009826	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
762903009827	serine O-acetyltransferase; Region: cysE; TIGR01172
762903009828	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
762903009829	trimer interface [polypeptide binding]; other site
762903009830	active site
762903009831	substrate binding site [chemical binding]; other site
762903009832	CoA binding site [chemical binding]; other site
762903009833	cysteine synthase B; Region: cysM; TIGR01138
762903009834	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
762903009835	dimer interface [polypeptide binding]; other site
762903009836	pyridoxal 5'-phosphate binding site [chemical binding]; other site
762903009837	catalytic residue [active]
762903009838	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
762903009839	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
762903009840	S-adenosylmethionine binding site [chemical binding]; other site
762903009841	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
762903009842	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
762903009843	active site
762903009844	shikimate kinase; Reviewed; Region: aroK; PRK00131
762903009845	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
762903009846	ADP binding site [chemical binding]; other site
762903009847	magnesium binding site [ion binding]; other site
762903009848	putative shikimate binding site; other site
762903009849	Predicted membrane protein [Function unknown]; Region: COG2259
762903009850	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
762903009851	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
762903009852	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
762903009853	dihydropteroate synthase; Region: DHPS; TIGR01496
762903009854	substrate binding pocket [chemical binding]; other site
762903009855	dimer interface [polypeptide binding]; other site
762903009856	inhibitor binding site; inhibition site
762903009857	TIGR00159 family protein; Region: TIGR00159
762903009858	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
762903009859	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
762903009860	dimer interface [polypeptide binding]; other site
762903009861	[2Fe-2S] cluster binding site [ion binding]; other site
762903009862	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
762903009863	Ferritin-like domain; Region: Ferritin; pfam00210
762903009864	ferroxidase diiron center [ion binding]; other site
762903009865	Ribokinase-like subgroup C.  Found only in bacteria, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_C; cd01946
762903009866	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
762903009867	substrate binding site [chemical binding]; other site
762903009868	ATP binding site [chemical binding]; other site
762903009869	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903009870	Immunoglobulin domain; Region: Ig_2; pfam13895
762903009871	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903009872	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903009873	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
762903009874	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903009875	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903009876	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903009877	ligand binding site [chemical binding]; other site
762903009878	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
762903009879	Immunoglobulin domain; Region: Ig_3; pfam13927
762903009880	Domain of unknown function DUF11; Region: DUF11; pfam01345
762903009881	Domain of unknown function DUF11; Region: DUF11; cl17728
762903009882	Domain of unknown function DUF11; Region: DUF11; cl17728
762903009883	Domain of unknown function DUF11; Region: DUF11; cl17728
762903009884	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
762903009885	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
762903009886	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; cl01132
762903009887	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
762903009888	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
762903009889	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
762903009890	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
762903009891	Integrase core domain; Region: rve; pfam00665
762903009892	Integrase core domain; Region: rve_3; pfam13683
762903009893	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
762903009894	Phosphotransferase enzyme family; Region: APH; pfam01636
762903009895	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903009896	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903009897	DNA binding site [nucleotide binding]
762903009898	domain linker motif; other site
762903009899	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903009900	dimerization interface [polypeptide binding]; other site
762903009901	ligand binding site [chemical binding]; other site
762903009902	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
762903009903	active site
762903009904	catalytic triad [active]
762903009905	Fasciclin domain; Region: Fasciclin; cl02663
762903009906	Fasciclin domain; Region: Fasciclin; cl02663
762903009907	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009908	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009909	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009910	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903009911	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903009912	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903009913	Fasciclin domain; Region: Fasciclin; pfam02469
762903009914	Fasciclin domain; Region: Fasciclin; cl02663
762903009915	Fasciclin domain; Region: Fasciclin; cl02663
762903009916	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009917	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009918	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009919	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009920	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903009921	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009922	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009923	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009924	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
762903009925	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903009926	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903009927	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903009928	Glycosyl hydrolase 43-like family consists of hypothetical proteins; Region: GH43_like_2; cd08994
762903009929	active site
762903009930	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009931	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903009932	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903009933	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903009934	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903009935	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009936	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
762903009937	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009938	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903009939	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903009940	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903009941	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903009942	dimer interface [polypeptide binding]; other site
762903009943	phosphorylation site [posttranslational modification]
762903009944	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903009945	ATP binding site [chemical binding]; other site
762903009946	Mg2+ binding site [ion binding]; other site
762903009947	G-X-G motif; other site
762903009948	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903009949	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903009950	active site
762903009951	phosphorylation site [posttranslational modification]
762903009952	intermolecular recognition site; other site
762903009953	dimerization interface [polypeptide binding]; other site
762903009954	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
762903009955	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903009956	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903009957	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903009958	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903009959	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
762903009960	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903009961	starch binding outer membrane protein SusD; Region: SusD; cd08977
762903009962	Pectate lyase; Region: Pec_lyase_C; cl01593
762903009963	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
762903009964	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
762903009965	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009966	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903009967	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009968	Glycosyl hydrolase family 47; Region: Glyco_hydro_47; cl08327
762903009969	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903009970	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
762903009971	Interdomain contacts; other site
762903009972	Cytokine receptor motif; other site
762903009973	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
762903009974	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
762903009975	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903009976	Glycoside hydrolase family 94 N-terminal-like domain of uncharacterized function; Region: GH94N_like_1; cd11747
762903009977	homodimer interface [polypeptide binding]; other site
762903009978	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
762903009979	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
762903009980	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
762903009981	Rhamnogalacturonan lyase of the polysaccharide lyase family 11; Region: RGL11; cd10318
762903009982	metal binding site [ion binding]; metal-binding site
762903009983	active site
762903009984	Glycosyl hydrolase family 43; Region: GH43_5; cd08984
762903009985	active site
762903009986	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
762903009987	active site
762903009988	catalytic triad [active]
762903009989	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
762903009990	active site
762903009991	catalytic triad [active]
762903009992	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903009993	Sulfatase; Region: Sulfatase; pfam00884
762903009994	Integrase core domain; Region: rve; pfam00665
762903009995	Integrase core domain; Region: rve_3; pfam13683
762903009996	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
762903009997	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903009998	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903009999	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903010000	putative alpha-glucosidase; Provisional; Region: PRK10658
762903010001	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
762903010002	Glycosyl hydrolases family 31; Region: Glyco_hydro_31; pfam01055
762903010003	active site
762903010004	catalytic site [active]
762903010005	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903010006	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
762903010007	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
762903010008	Domain of unknown function (DUF718); Region: DUF718; pfam05336
762903010009	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
762903010010	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
762903010011	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
762903010012	ligand binding site [chemical binding]; other site
762903010013	flexible hinge region; other site
762903010014	Helix-turn-helix domain; Region: HTH_17; pfam12728
762903010015	TIGR02594 family protein; Region: TIGR02594
762903010016	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
762903010017	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
762903010018	Cna protein B-type domain; Region: Cna_B_2; pfam13715
762903010019	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
762903010020	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
762903010021	starch binding outer membrane protein SusD; Region: SusD; cl17845
762903010022	SusD family; Region: SusD; pfam07980
762903010023	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
762903010024	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
762903010025	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
762903010026	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
762903010027	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
762903010028	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
762903010029	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
762903010030	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
762903010031	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
762903010032	nucleotide binding site [chemical binding]; other site
762903010033	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
762903010034	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
762903010035	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
762903010036	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
762903010037	putative substrate translocation pore; other site
762903010038	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
762903010039	Beta-lactamase; Region: Beta-lactamase; pfam00144
762903010040	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
762903010041	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
762903010042	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
762903010043	Heparinase II/III-like protein; Region: Hepar_II_III; cl15421
762903010044	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
762903010045	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_2; cd09001
762903010046	active site
762903010047	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903010048	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
762903010049	DNA binding site [nucleotide binding]
762903010050	domain linker motif; other site
762903010051	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
762903010052	dimerization interface [polypeptide binding]; other site
762903010053	ligand binding site [chemical binding]; other site
762903010054	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
762903010055	DNA-binding site [nucleotide binding]; DNA binding site
762903010056	Ligand-binding domain of a transcription repressor, FucR, which functions as a molecular sensor of L-fucose availability; Region: PBP1_FucR_like; cd06276
762903010057	putative dimerization interface [polypeptide binding]; other site
762903010058	putative ligand binding site [chemical binding]; other site
762903010059	Transcriptional regulators [Transcription]; Region: PurR; COG1609
762903010060	rhamnose-proton symporter; Provisional; Region: PRK13499
762903010061	short chain dehydrogenase; Validated; Region: PRK08324
762903010062	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
762903010063	active site
762903010064	Zn2+ binding site [ion binding]; other site
762903010065	intersubunit interface [polypeptide binding]; other site
762903010066	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903010067	NAD(P) binding site [chemical binding]; other site
762903010068	active site
762903010069	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
762903010070	L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype; Region: L_rham_iso_rhiz; TIGR02629
762903010071	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
762903010072	nucleotide binding site [chemical binding]; other site
762903010073	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
762903010074	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
762903010075	Walker A/P-loop; other site
762903010076	ATP binding site [chemical binding]; other site
762903010077	Q-loop/lid; other site
762903010078	ABC transporter signature motif; other site
762903010079	Walker B; other site
762903010080	D-loop; other site
762903010081	H-loop/switch region; other site
762903010082	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
762903010083	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
762903010084	DNA polymerase III subunit beta; Validated; Region: PRK05643
762903010085	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
762903010086	putative DNA binding surface [nucleotide binding]; other site
762903010087	dimer interface [polypeptide binding]; other site
762903010088	beta-clamp/clamp loader binding surface; other site
762903010089	beta-clamp/translesion DNA polymerase binding surface; other site
762903010090	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
762903010091	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
762903010092	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
762903010093	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
762903010094	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
762903010095	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
762903010096	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
762903010097	Zinc dependent phospholipase C/S1-P1 nuclease; Region: ZnPC_S1P1; cd10981
762903010098	Zn binding site [ion binding]; other site
762903010099	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
762903010100	hypothetical protein; Reviewed; Region: PRK00024
762903010101	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
762903010102	MPN+ (JAMM) motif; other site
762903010103	Zinc-binding site [ion binding]; other site
762903010104	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
762903010105	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
762903010106	putative tRNA-binding site [nucleotide binding]; other site
762903010107	B3/4 domain; Region: B3_4; pfam03483
762903010108	tRNA synthetase B5 domain; Region: B5; smart00874
762903010109	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
762903010110	dimer interface [polypeptide binding]; other site
762903010111	motif 1; other site
762903010112	motif 3; other site
762903010113	motif 2; other site
762903010114	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
762903010115	Cell division protein ZapA; Region: ZapA; pfam05164
762903010116	phosphodiesterase; Provisional; Region: PRK12704
762903010117	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
762903010118	Zn2+ binding site [ion binding]; other site
762903010119	Mg2+ binding site [ion binding]; other site
762903010120	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
762903010121	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
762903010122	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
762903010123	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
762903010124	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
762903010125	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
762903010126	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
762903010127	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
762903010128	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
762903010129	Metal-binding active site; metal-binding site
762903010130	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
762903010131	Cytochrome c; Region: Cytochrom_C; cl11414
762903010132	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
762903010133	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
762903010134	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
762903010135	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
762903010136	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
762903010137	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
762903010138	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
762903010139	active site
762903010140	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
762903010141	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
762903010142	ligand binding site [chemical binding]; other site
762903010143	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
762903010144	Two component regulator propeller; Region: Reg_prop; pfam07494
762903010145	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
762903010146	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903010147	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903010148	dimer interface [polypeptide binding]; other site
762903010149	phosphorylation site [posttranslational modification]
762903010150	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903010151	ATP binding site [chemical binding]; other site
762903010152	Mg2+ binding site [ion binding]; other site
762903010153	G-X-G motif; other site
762903010154	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
762903010155	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
762903010156	active site
762903010157	phosphorylation site [posttranslational modification]
762903010158	intermolecular recognition site; other site
762903010159	dimerization interface [polypeptide binding]; other site
762903010160	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
762903010161	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903010162	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
762903010163	putative catalytic site [active]
762903010164	putative metal binding site [ion binding]; other site
762903010165	putative phosphate binding site [ion binding]; other site
762903010166	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903010167	Sulfatase; Region: Sulfatase; pfam00884
762903010168	Lyase, N terminal; Region: Lyase_N; pfam09092
762903010169	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cl17706
762903010170	substrate binding site [chemical binding]; other site
762903010171	catalytic residues [active]
762903010172	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
762903010173	Sulfatase; Region: Sulfatase; pfam00884
762903010174	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
762903010175	substrate binding site [chemical binding]; other site
762903010176	catalytic residues [active]
762903010177	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
762903010178	putative active site [active]
762903010179	Domain of unknown function (DUF389); Region: DUF389; pfam04087
762903010180	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
762903010181	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
762903010182	Domain of unknown function (DUF4147); Region: DUF4147; pfam13660
762903010183	Putative glycerate kinase [Carbohydrate transport and metabolism]; Region: GckA; COG2379
762903010184	MOFRL family; Region: MOFRL; pfam05161
762903010185	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
762903010186	fructuronate transporter; Provisional; Region: PRK10034; cl15264
762903010187	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
762903010188	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
762903010189	potential catalytic triad [active]
762903010190	conserved cys residue [active]
762903010191	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
762903010192	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
762903010193	NAD(P) binding site [chemical binding]; other site
762903010194	active site
762903010195	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
762903010196	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
762903010197	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
762903010198	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
762903010199	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
762903010200	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
762903010201	dimer interface [polypeptide binding]; other site
762903010202	phosphorylation site [posttranslational modification]
762903010203	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
762903010204	ATP binding site [chemical binding]; other site
762903010205	Mg2+ binding site [ion binding]; other site
762903010206	G-X-G motif; other site
762903010207	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
762903010208	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
762903010209	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
762903010210	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
762903010211	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
762903010212	RecA/RadA recombinase [DNA replication, recombination, and repair]; Region: RecA; COG0468
762903010213	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
762903010214	hexamer interface [polypeptide binding]; other site
762903010215	Walker A motif; other site
762903010216	ATP binding site [chemical binding]; other site
762903010217	Walker B motif; other site
762903010218	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
762903010219	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
762903010220	minor groove reading motif; other site
762903010221	helix-hairpin-helix signature motif; other site
762903010222	substrate binding pocket [chemical binding]; other site
762903010223	active site
762903010224	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
762903010225	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
762903010226	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
762903010227	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
762903010228	substrate binding pocket [chemical binding]; other site
762903010229	chain length determination region; other site
762903010230	substrate-Mg2+ binding site; other site
762903010231	catalytic residues [active]
762903010232	aspartate-rich region 1; other site
762903010233	active site lid residues [active]
762903010234	aspartate-rich region 2; other site
762903010235	hypothetical protein; Provisional; Region: PRK12378
762903010236	Lamin Tail Domain; Region: LTD; pfam00932
762903010237	Lamin Tail Domain; Region: LTD; pfam00932
762903010238	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
762903010239	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
762903010240	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
762903010241	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
762903010242	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
762903010243	LytB protein; Region: LYTB; cl00507
762903010244	ferrochelatase; Reviewed; Region: hemH; PRK00035
762903010245	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
762903010246	C-terminal domain interface [polypeptide binding]; other site
762903010247	active site
762903010248	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
762903010249	active site
762903010250	N-terminal domain interface [polypeptide binding]; other site
762903010251	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
762903010252	RES domain; Region: RES; pfam08808
762903010253	Domain of unknown function (DUF4320); Region: DUF4320; pfam14208
762903010254	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
762903010255	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
762903010256	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
762903010257	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
762903010258	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
762903010259	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
762903010260	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
762903010261	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
762903010262	NAD binding site [chemical binding]; other site
762903010263	putative substrate binding site 2 [chemical binding]; other site
762903010264	putative substrate binding site 1 [chemical binding]; other site
762903010265	active site
762903010266	UDP-glucose 4-epimerase; Region: PLN02240
762903010267	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
762903010268	NAD binding site [chemical binding]; other site
762903010269	homodimer interface [polypeptide binding]; other site
762903010270	active site
762903010271	substrate binding site [chemical binding]; other site
762903010272	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
762903010273	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
762903010274	NAD binding site [chemical binding]; other site
762903010275	substrate binding site [chemical binding]; other site
762903010276	homodimer interface [polypeptide binding]; other site
762903010277	active site
762903010278	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
762903010279	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
762903010280	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
762903010281	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
762903010282	FtsX-like permease family; Region: FtsX; pfam02687
762903010283	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
762903010284	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872