-- dump date   	20140619_233148
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_001210551.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_001210552.1	PCNA homolog
YP_001210553.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_001210555.1	DNA gyrase/topo II, topoisomerase IV
YP_001210556.1	containing HAMP and methyl-accepting chemotaxis-like domains
YP_001210558.1	DNA gyrase/topo II topoisomerase IV
YP_001210559.1	with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate
YP_001210560.1	with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate
YP_001210562.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_001210563.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001210568.1	flavoproteins
YP_001210578.1	containing COG4624, iron only hydrogenase large subunit, C-terminal domain; COG2000, predicted Fe-S protein; and PAS domain
YP_001210581.1	containing partial COG0388, predicted amidohydrolase
YP_001210585.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001210586.1	containing COG5002, VicK, signal transduction histidine kinase domain
YP_001210591.1	containing partial ArnT (COG1807), 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YP_001210596.1	containing Rubrerythrin domain (COG1592), Osmosensitive K+ channel histidine kinase.
YP_001210597.1	containing partial KdpD (COG2205)
YP_001210598.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001210600.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_001210603.1	RecF pathway
YP_001210630.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_001210632.1	containing partial COG1216 predicted glycosyltransferases
YP_001210638.1	containing LysM domain
YP_001210643.1	membrane protein
YP_001210645.1	containing partial ErfK (COG1376), Uncharacterized protein conserved in bacteria and partial LytE (COG1388), FOG: LysM repeat.
YP_001210646.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_001210649.1	containing acetyltransf_1, Acetyltransferase (GNAT)
YP_001210650.1	nitrogenspecific
YP_001210652.1	catalyzes the formation of 2-oxobutanoate from L-threonine
YP_001210653.1	involved in the regulation of septum location
YP_001210654.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_001210660.1	molecular chaperone
YP_001210662.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_001210667.1	containing SrmB, superfamily II DNA and RNA helicases (COG0513) and TRCF domain
YP_001210670.1	containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain
YP_001210672.1	implicated in the recycling of the 50S subunit (S4 paralog)
YP_001210687.1	related to C-terminal domain of eukaryotic chaperone, SACSIN
YP_001210692.1	containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198)
YP_001210693.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001210697.1	AAA+ superfamily
YP_001210698.1	containing TPR Domain
YP_001210709.1	containing PinR, site-specific recombinases, DNA invertase Pin homologs (COG1961)
YP_001210728.1	containing partial XerD (COG4974), site-specific recombinase XerD
YP_001210729.1	containing HTH_3, Helix-turn-helix
YP_001210731.1	DNA invertase Pin homologs
YP_001210736.1	SLH, S-layer homology domain
YP_001210739.1	contains ribosomal protein S1 domain
YP_001210740.1	partial GppA (COG0248), Exopolyphosphatase
YP_001210741.1	containing PTC1 (COG0631), serine/threonine protein phosphatase
YP_001210743.1	containing SLH, S-layer homology domain.
YP_001210746.1	involved in benzoate metabolism
YP_001210747.1	PP-loop superfamily implicated in cell cycle control
YP_001210749.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_001210750.1	catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate
YP_001210751.1	containing methyl-accepting chemotaxis protein (COG0840) and Cache domain
YP_001210752.1	containing HAMP (Histidine kinases, Adenylyl cyclases, methyl binding proteins, Phosphatases) and MA, methyl-accepting chemotaxis-like domain
YP_001210753.1	containing FolP Dihydropteroate synthase and related enzyme (COG0294)
YP_001210763.1	containing partial XerD (COG4974), site-specific recombinase XerD
YP_001210767.1	containing COG1061, SSL2, DNA or RNA helicases of superfamily II
YP_001210770.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_001210771.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_001210772.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_001210775.1	containing Phage_integrase
YP_001210779.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_001210789.1	catalyzes the reduction of adenosine 5'-phosphosulfate to AMP and sulfite
YP_001210791.1	sulfate adenylyltransferase
YP_001210793.1	regulator of disulfide bond formation
YP_001210794.1	involved in molybdopterin and thiamine biosynthesis family 2
YP_001210795.1	containing OmpR response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain (COG0745)
YP_001210796.1	containing BaeS signal transduction histidine kinase (COG0642)
YP_001210801.1	containing partial UbiE (COG2226), methylase involved in ubiquinone/menaquinone biosynthesis
YP_001210802.1	PP-loop superfamily
YP_001210806.1	containing BioY uncharacterized conserved protein (COG1268)
YP_001210808.1	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP
YP_001210813.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_001210814.1	containing uncharacterized protein family (UPF0169)
YP_001210817.1	containing NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family (COG1902) and TrxB, thioredoxin reductase (COG0492)
YP_001210823.1	converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA
YP_001210831.1	with conserved CXXC pairs
YP_001210835.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_001210836.1	non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair
YP_001210837.1	similar to M. xanthus CarD
YP_001210838.1	PIN domain superfamily
YP_001210839.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_001210845.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_001210848.1	flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor
YP_001210850.1	containing a PIN domain
YP_001210851.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_001210852.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001210853.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif
YP_001210854.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_001210856.1	binds directly to 23S ribosomal RNA
YP_001210857.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_001210858.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_001210859.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_001210863.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_001210864.1	S12/L30/L7a
YP_001210865.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_001210866.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_001210867.1	GTPase
YP_001210868.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001210870.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_001210871.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_001210872.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_001210873.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_001210874.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_001210876.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_001210877.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_001210878.1	one of the stabilizing components for the large ribosomal subunit
YP_001210880.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_001210881.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_001210882.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_001210883.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_001210885.1	binds 5S rRNA along with protein L5 and L25
YP_001210886.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_001210888.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_001210889.1	late assembly protein
YP_001210890.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_001210893.1	IF-1
YP_001210895.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_001210896.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_001210898.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_001210899.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_001210900.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_001210905.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_001210906.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_001210907.1	forms a direct contact with the tRNA during translation
YP_001210914.1	contains PIN domain
YP_001210919.1	containing HisB (COG0131), imidazoleglycerol-phosphate dehydratase
YP_001210920.1	containing PGM_PMM_IV, Phosphoglucomutase/phosphomannomutase, C-terminal domain
YP_001210928.1	flavoproteins
YP_001210930.1	isoleucine patch superfamily
YP_001210932.1	involved in cell wall biogenesis
YP_001210943.1	involved in regulation of cell wall biogenesis
YP_001210944.1	involved in the export of O-antigen and teichoic acid
YP_001210947.1	toxin-antitoxin stability system
YP_001210953.1	contains PIN domain
YP_001210960.1	containing COG1061, SSL2, DNA or RNA helicases of superfamily II and COG4279, uncharacterized conserved protein
YP_001210961.1	contains PIN domain
YP_001210967.1	containing two S-layer homology (SLH) domain
YP_001210969.1	containing three S-layer homology SLH) domains
YP_001210974.1	containing Gas vesicle protein
YP_001210976.1	containing Gas vesicle synthesis protein GvpL/GvpF
YP_001210978.1	containing Gas vesicle synthesis protein GvpL/GvpF
YP_001210979.1	containing GvpG, Gas vesicle protein G
YP_001210980.1	containing GvpL_GvpF, Gas vesicle synthesis protein GvpL/GvpF
YP_001210981.1	AAA+ class
YP_001210985.1	containing Gas vesicle protein
YP_001210987.1	related to C-terminal domain of eukaryotic chaperone, SACSIN
YP_001210990.1	in Rhodopseudomonas palustris this protein confers resistance to arsenite; catalyzes the formation of a number of methylated intermediates from arsenite and SAM producing trimethylarsine
YP_001210995.1	containing NapF, ferredoxin (COG1145)
YP_001210999.1	typically periplasmic, contain C-terminal PDZ domain
YP_001211000.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001211017.1	containing AMMECR1 uncharacterized conserved protein (COG2078) and uncharacterized conserved protein (COG3885)
YP_001211019.1	containing DRG, predicted GTPase (COG1163) and TGS domain
YP_001211023.1	containing Polysacc_deac_1, Polysaccharide deacetylase.
YP_001211028.1	containing ferredoxin (COG1146)
YP_001211032.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_001211033.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_001211034.1	class IV
YP_001211035.1	containing MoCF_biosynth, Probable molybdopterin binding domain
YP_001211036.1	containing hydrogenase components 2
YP_001211038.1	class IV
YP_001211040.1	NDP forming
YP_001211045.1	class IV
YP_001211047.1	involved in thiamine biosynthesis
YP_001211048.1	involved in molybdopterin and thiamine biosynthesis family 2
YP_001211049.1	contains PIN domain
YP_001211051.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_001211052.1	N-acetylornithine aminotransferase
YP_001211053.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_001211054.1	catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine
YP_001211056.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation
YP_001211057.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_001211058.1	aromatic amino acids metabolism
YP_001211060.1	class IV
YP_001211064.1	ETF
YP_001211067.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_001211075.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_001211077.1	acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase
YP_001211078.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_001211079.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_001211080.1	acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase
YP_001211081.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
YP_001211082.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis
YP_001211083.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis
YP_001211084.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_001211088.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_001211089.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_001211091.1	containing prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain.
YP_001211092.1	azaleucine resistance
YP_001211096.1	containing COG2206, HD-GYP domain and FhlA (COG2203), FOG: GAF domain
YP_001211098.1	containing von Willebrand factor type A (vWA) domain
YP_001211101.1	regulator of disulfide bond formation
YP_001211106.1	ABC class
YP_001211107.1	flavoproteins
YP_001211117.1	metallo-beta-lactamase superfamily
YP_001211118.1	HSP70-class ATPase domain
YP_001211127.1	containing DsrE (COG1553), uncharacterized conserved protein involved in intracellular sulfur reduction
YP_001211128.1	BcrC/BadD/HgdB
YP_001211129.1	typically selenocysteine-containing
YP_001211131.1	involved in Fe-S cluster formation
YP_001211132.1	containing NifB domain
YP_001211134.1	containing an inserted ferredoxin domain
YP_001211135.1	containing an inserted ferredoxin domain
YP_001211136.1	containing NifB domain
YP_001211142.1	related to short-chain alcohol dehydrogenases
YP_001211145.1	Old Yellow Enzyme family
YP_001211146.1	containing TrxB (COG0492), thioredoxin reductase domain
YP_001211148.1	flavoproteins
YP_001211150.1	containing partial FixA (COG2086), electron transfer flavoprotein, beta subunit
YP_001211151.1	containing COG1216, predicted glycosyltransferases
YP_001211155.1	containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
YP_001211156.1	class IV
YP_001211157.1	containing an HD domain
YP_001211158.1	catalyzes the formation of L-tryptophan from indole and L-serine
YP_001211162.1	involved in molybdopterin and thiamine biosynthesis family 2
YP_001211163.1	containing C-terminal beta-propeller domain distantly related to WD-40 repeats
YP_001211164.1	containing SLH domain
YP_001211165.1	SIR2 family
YP_001211168.1	HAD superfamily
YP_001211170.1	containing partial COG0218, predicted GTPase
YP_001211179.1	cytochrome b1
YP_001211180.1	containing partial IbpA (COG0071), molecular chaperone (small heat shock protein)
YP_001211186.1	containing partial Tar (COG0840), methyl-accepting chemotaxis protein
YP_001211188.1	containing AbrB regulators of stationary/sporulation gene expression (COG2002) domain
YP_001211189.1	involved in thiamine biosynthesis
YP_001211190.1	thiazole biosynthesis
YP_001211192.1	catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate
YP_001211194.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_001211195.1	domain typically associated with flavoprotein oxygenases, DIM6/NTAB family
YP_001211196.1	the C-terminal domain of histone macroH2A1
YP_001211204.1	containing LytS (COG3275), putative regulator of cell autolysis
YP_001211205.1	LytR/AlgR family
YP_001211206.1	holo-ACP synthase
YP_001211207.1	containing predicted sugar kinase (COG0063) and uncharacterized conserved protein (COG0062) domains
YP_001211216.1	containing Rtn (COG2200), FOG: EAL domain
YP_001211218.1	containig ferredoxin
YP_001211221.1	sigma24 homolog
YP_001211223.1	glutamine-hydrolyzing
YP_001211228.1	containing CheY-like receiver, AAA-type ATPase and DNA-binding domains
YP_001211229.1	containing COG1229 CoxL and COG2080 CoxS
YP_001211230.1	containing GlpC (COG0247), Fe-S oxidoreductase and partial GltD (COG0493), NADPH-dependent glutamate synthase beta chain and related oxidoreductases
YP_001211236.1	XdhC/CoxF family
YP_001211238.1	containing partial MoaB (COG0521), molybdopterin biosynthesis enzyme
YP_001211243.1	DNA invertase Pin homologs
YP_001211244.1	contains PIN domain
YP_001211248.1	involved in RNA processing
YP_001211253.1	contains PIN domain
YP_001211257.1	containing partial COG1367, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
YP_001211258.1	containing partial COG1604, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)
YP_001211260.1	containing partial COG3547, transposase and inactivated derivatives
YP_001211262.1	predicted to be involved in DNA repair (RAMP superfamily)
YP_001211266.1	containing partial HepA (COG0553), superfamily II DNA/RNA helicases, SNF2 family
YP_001211274.1	containing large family of predicted nucleotide-binding domains (PINc)
YP_001211275.1	containing HipB (COG1396), predicted transcriptional regulator and COG2856, predicted Zn peptidase
YP_001211277.1	with putative antiterminator output domain
YP_001211280.1	with putative antiterminator output domain
YP_001211286.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_001211292.1	putative molecular chaperone
YP_001211294.1	containing FtsA resion (actin-like ATPase involved in cell division, COG0849)
YP_001211298.1	implicated in signal transduction
YP_001211299.1	implicated in signal transduction
YP_001211300.1	containing predicted hydrocarbon binding protein (contains V4R domain) resion (COG1719)
YP_001211302.1	nitrogen specific
YP_001211307.1	containing uncharacterized conserved region (COG2456)
YP_001211308.1	containing uncharacterized conserved region (COG3881)
YP_001211310.1	contains PIN domain
YP_001211315.1	containing TolB (COG0823), periplasmic component of the Tol biopolymer transport system.
YP_001211318.1	sigma24 homolog
YP_001211329.1	catalyzes the reduction of hydroxylamine to ammonia and water
YP_001211330.1	containing ferredoxin region (COG1146)
YP_001211331.1	catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
YP_001211336.1	containing N-acetylmuramoyl-L-alanine amidase region (COG0860 AmiC) and SH3b domain
YP_001211338.1	BcrC/BadD/HgdB
YP_001211339.1	HSP70-class ATPase domain
YP_001211340.1	beta-lactamase superfamily III
YP_001211341.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_001211342.1	hydrolyzes non-standard nucleotides such as xanthine and inosine
YP_001211346.1	containing methyl-accepting chemotaxis protein region (COG0840)
YP_001211349.1	containing partial COG1418, predicted HD superfamily hydrolase
YP_001211351.1	containing FOG:CBS domain (COG0517) and GGDEF domain
YP_001211353.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_001211355.1	binds and unfolds substrates as part of the ClpXP protease
YP_001211357.1	bacterial type
YP_001211358.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_001211362.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_001211365.1	implicated in inhibition of septum formation
YP_001211367.1	functions in MreBCD complex in some organisms
YP_001211368.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_001211370.1	FtsI/penicillin-binding protein 2
YP_001211375.1	related to metalloendopeptidases
YP_001211381.1	involved in the peptidyltransferase reaction during translation
YP_001211384.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_001211385.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
YP_001211386.1	Partial COG0724, RNA-binding proteins (RRM domain)
YP_001211389.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_001211394.1	containing PAS, AAA-type ATPase, and DNA-binding domains
YP_001211400.1	containing PAS, AAA-type ATPase, and DNA-binding domains
YP_001211401.1	class IV
YP_001211404.1	containing DNA uptake protein and related DNA-binding protein region (ComEA, COG1555)
YP_001211406.1	containing partial COG3953, SLT domain proteins
YP_001211407.1	metallo-beta-lactamase superfamily, containing predicted metal-binding region
YP_001211408.1	containing superfamily II DNA/RNA helicases region (COG0553 HepA)
YP_001211410.1	containing a Zn-ribbon
YP_001211413.1	AAA+ superfamily
YP_001211419.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_001211423.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_001211426.1	HSP60 family
YP_001211427.1	heat shock protein
YP_001211428.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_001211429.1	with C-terminal Zn finger domain
YP_001211430.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_001211431.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_001211432.1	containing partial region of 2-methylthioadenine synthetase (COG0621 MiaB)
YP_001211433.1	Partial MiaB (COG0621), 2-methylthioadenine synthetase
YP_001211435.1	Fe-S oxidoreductase
YP_001211438.1	containing DUF1429 domain
YP_001211439.1	containing Yqf domain
YP_001211440.1	PhoH, predicted ATPase
YP_001211443.1	containing diacylglycerol kinase region (COG0818 DgkA)
YP_001211447.1	RecF pathway
YP_001211449.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001211451.1	containing COG0517, FOG:CBS domain
YP_001211453.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_001211455.1	dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate
YP_001211456.1	bacterial type
YP_001211457.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium
YP_001211464.1	containing COG0327 and COG3323 domain
YP_001211466.1	including yeast histone deacetylase and acetoin utilization protein
YP_001211467.1	including oxidative damage repair enzymes
YP_001211468.1	containing NAD synthase region (COG0171 NadE) and predicted amidohydrolase region (COG0388)
YP_001211470.1	catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate
YP_001211477.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_001211478.1	homolog of pyruvate formate lyase activating proteins
YP_001211484.1	the beta-lactamase fold involved in RNA processing
YP_001211485.1	containing uncharacterized conserved region (COG1598)
YP_001211494.1	PvlArgDC; converts arginine to agmatine and carbon dioxide; has a role in polyamine metabolism; in Methanococcus jannaschii this enzyme self-cleaves at serine-serine bond to form alpha (N-terminal) and beta (C-terminal) subunits; the alpha subunit contains a catalytically active pyruvoyl group; the beta subunit contains the substrate-binding residues; forms homotrimers of the alpha/beta complex
YP_001211496.1	arginase family
YP_001211501.1	COG1903 CbiD, containing ABC-type cobalt transport system, ATPase component (COG1122 CbiO)
YP_001211502.1	containing COG2241 and COG2242
YP_001211506.1	COG1010, CobJ and COG2099, CobK
YP_001211507.1	containing CbiX domain
YP_001211508.1	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
YP_001211509.1	responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid
YP_001211510.1	long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors
YP_001211517.1	containing partial uncharacterized Fe-S protein region (COG1600)
YP_001211518.1	containing HTH_4 domain
YP_001211520.1	precorrin-2 oxidase/ferrochelatase domain
YP_001211521.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_001211522.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_001211523.1	COG0007 CysG and COG1587 HemD
YP_001211525.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_001211531.1	catalyzes the formation of fumarate from aspartate
YP_001211533.1	catalyzes the formation of biotin from dethiobiotin and sulfur
YP_001211534.1	in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; in Thermotoga this enzyme has an extra C-terminal domain
YP_001211535.1	modulates transcription in response to the NADH/NAD(+) redox state
YP_001211538.1	ACT domain-containing protein
YP_001211539.1	the alpha-beta hydrolase superfamily
YP_001211545.1	a riboflavin/FAD biosynthetic operon
YP_001211546.1	hemoprotein
YP_001211551.1	part of a complex that catalyzes the cleavage of acetyl-CoA
YP_001211553.1	part of a complex that catalyzes the cleavage of acetyl-CoA
YP_001211554.1	catalyzes the transfer of the N5-methyl group from (6S)-methyl tetrahydrofolate to the cobalt center of a corrinoid iron-sulfur protein
YP_001211558.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
YP_001211560.1	containing partial DnaC (COG1484), DNA replication protein
YP_001211561.1	involved in spore germination
YP_001211562.1	containing partial COG1302, Uncharacterized protein conserved in bacteria
YP_001211563.1	penicillin-binding protein
YP_001211567.1	part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_001211568.1	part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_001211570.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_001211572.1	possibly involved in aromatic compounds catabolism
YP_001211573.1	containing LytE (COG1388), FOG: LysM repeat
YP_001211575.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_001211577.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_001211581.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_001211582.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_001211585.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_001211586.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_001211588.1	containing DksA (COG1734), DnaK suppressor protein
YP_001211593.1	containing RecJ, Single-stranded DNA-specific exonuclease domain (COG0608) and HELICc, Helicase superfamily c-terminal domain
YP_001211596.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
YP_001211597.1	including glyoxylases
YP_001211598.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_001211599.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_001211600.1	involved in molybdopterin and thiamine biosynthesis family 1
YP_001211602.1	related to the helicase subunit of the holliday junction resolvase
YP_001211605.1	involved in Fe-S cluster formation
YP_001211606.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_001211612.1	catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate
YP_001211614.1	related to aryl-alcohol dehydrogenases
YP_001211615.1	involved in recombination
YP_001211620.1	FtsI/penicillin-binding protein 2
YP_001211621.1	containing two HipB (COG1476) domains
YP_001211624.1	containing partial UbiE (COG2226), methylase involved in ubiquinone/menaquinone biosynthesis
YP_001211627.1	containing partial ArnT (COG1807), 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YP_001211632.1	containing partial RfaG (COG0438), glycosyltransferase
YP_001211635.1	containing partial UbiE (COG2226), methylase involved in ubiquinone/menaquinone biosynthesis
YP_001211637.1	containing partial TesA (COG2755), Lysophospholipase L1 and related esterases
YP_001211639.1	involved in D-alanine export
YP_001211642.1	containing partial COG3103, SH3 domain protein
YP_001211649.1	containing partial COG3146, Uncharacterized protein conserved in bacteria
YP_001211650.1	involved in lipopolysaccharide synthesis
YP_001211652.1	containing fibronectin type 3 domain
YP_001211655.1	containing Wzy_C, O-Antigen Polymerase domain
YP_001211658.1	putative virulence factor
YP_001211664.1	involved in regulation of cell wall biogenesis
YP_001211665.1	involved in regulation of cell wall biogenesis
YP_001211668.1	containing WcaA (COG0463), glycosyltransferases involved in cell wall biogenesis and PilF (COG3063), tfp pilus assembly protein PilF
YP_001211669.1	containing WcaA (COG0463), glycosyltransferases involved in cell wall biogenesis and TPR, Tetratricopeptide repeat domain
YP_001211670.1	containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases
YP_001211673.1	containing COG0863, DNA modification methylase
YP_001211675.1	containing COG1961 domain
YP_001211676.1	containing COG1191 domain
YP_001211678.1	the HAD superfamily
YP_001211680.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_001211681.1	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_001211685.1	pilus retraction ATPase PilT
YP_001211706.1	containing PulG (COG2165), type II secretory pathway, pseudopilin PulG and COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor
YP_001211712.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_001211715.1	HR-like lesion-inducing. Family of plant proteins that are associated with the hypersensitive response (HR) pathway of defence against plant pathogens
YP_001211717.1	necessary for complete engulfment of forespore
YP_001211724.1	catalyzes the formation of oxaloacetate from pyruvate
YP_001211731.1	function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain
YP_001211742.1	containing PAS, AAA-type ATPase, and DNA-binding domains
YP_001211753.1	containing a CheY-like receiver domain and an HTH DNA-binding domain
YP_001211755.1	catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA
YP_001211761.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
YP_001211764.1	involved in D-alanine export
YP_001211771.1	predicted ATPase
YP_001211774.1	antagonist of anti-sigma factor
YP_001211775.1	binds to sigma F preventing its association with RNA polymerase during sporulation
YP_001211779.1	containing partial FabH (COG0332), 3-oxoacyl-[acyl-carrier-protein]
YP_001211784.1	HSP70-class ATPase domain
YP_001211786.1	containing COG0517and COG0617 domains
YP_001211788.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001211795.1	involved in DNA uptake
YP_001211797.1	TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine
YP_001211799.1	heat shock protein involved in degradation of misfolded proteins
YP_001211800.1	heat shock protein involved in degradation of misfolded proteins
YP_001211801.1	CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
YP_001211802.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_001211803.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_001211804.1	Catalyzes the phosphorylation of UMP to UDP
YP_001211805.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_001211810.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_001211812.1	involved in the deoxyxylulose pathway of isoprenoid biosynthesis
YP_001211815.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_001211816.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_001211817.1	implicated in transcription termination
YP_001211818.1	S12/L30/L7a
YP_001211819.1	IF-2; GTPase
YP_001211820.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_001211825.1	polynucleotide phosphorylase
YP_001211832.1	containing partial SppA (COG0616), Periplasmic serine proteases (ClpP class)
YP_001211833.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_001211834.1	catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance
YP_001211835.1	involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme
YP_001211837.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive
YP_001211838.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_001211839.1	metallo-beta-lactamase superfamily
YP_001211844.1	catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
YP_001211850.1	Conjugated protein of two COG1058, predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA
YP_001211852.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
YP_001211853.1	containing COG1431, Uncharacterized protein containing piwi/argonaute domain
YP_001211857.1	PHP family
YP_001211859.1	eIF-2B alpha/beta/delta family
YP_001211866.1	metallo-beta-lactamase superfamily
YP_001211868.1	containing GuaB (COG0516), IMP dehydrogenase/GMP reductase and FOG (COG0517): CBS domain
YP_001211869.1	containing partial COG3153, predicted acetyltransferase
YP_001211870.1	(IM30), sigma54-dependent transcription
YP_001211872.1	with SCP/PR1 domains
YP_001211875.1	HSP70-class ATPase domain
YP_001211878.1	small heat shock protein
YP_001211879.1	including oxidative damage repair enzymes
YP_001211888.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_001211889.1	This protein performs the mismatch recognition step during the DNA repair process
YP_001211891.1	including yeast histone deacetylase and acetoin utilization protein
YP_001211892.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_001211897.1	involved in aluminum resistance
YP_001211899.1	regulating citrate/malate metabolism
YP_001211900.1	citrate/malate metabolism
YP_001211903.1	RecA-mediated autopeptidases
YP_001211904.1	containing COG3039, transposase and inactivated derivatives, IS5 family
YP_001211905.1	containing PAS, AAA-type ATPase, and DNA-binding domains, RocR
YP_001211906.1	Catalyzes the reversible hydration of fumaric acid to yield I-malic acid
YP_001211907.1	tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
YP_001211912.1	cobalamin-binding
YP_001211913.1	lactoylglutathione lyase and related lyases
YP_001211914.1	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
YP_001211915.1	hypothetical membrane protein
YP_001211916.1	acetyl/propionyl-CoA carboxylase, alpha subunit
YP_001211917.1	Catalyzes the reversible oxidation of malate to oxaloacetate
YP_001211918.1	pyruvate/oxaloacetate carboxyltransferase
YP_001211919.1	related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit
YP_001211920.1	containing Zn_dep_PLPC, Zinc dependent phospholipase C.
YP_001211927.1	containing COG3383, Uncharacterized anaerobic dehydrogenase, COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
YP_001211940.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_001211944.1	containing partial RepA (COG3598), RecA-family ATPase
YP_001211945.1	GTPase
YP_001211946.1	involved in the export of O-antigen and teichoic acid
YP_001211947.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_001211949.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_001211951.1	DUF366, Domain of unknown function (DUF366). Archaeal domain of unknown function
YP_001211956.1	containing COG1150, HdrC, heterodisulfide reductase, subunit C
YP_001211964.1	containing COG1199 Rad3-related DNA helicases and COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
YP_001211965.1	catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins
YP_001211968.2	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_001211970.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001211971.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_001211972.1	containing AtoS (COG2202), FOG: PAS/PAC domain, NtrB (COG3852), signal transduction histidine kinase, nitrogen specific and PAS domain
YP_001211974.1	containing partial COG3315, O-methyltransferase involved in polyketide biosynthesis
YP_001211978.1	catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis
YP_001211981.1	containing partial ErfK (COG1376), Uncharacterized protein conserved in bacteria
YP_001211982.1	containing partial XerD (COG4974), site-specific recombinase XerD
YP_001211984.1	containing TOPRIM domain, potential nuclease
YP_001211990.1	IspA (COG0142), geranylgeranyl pyrophosphate synthase
YP_001211991.1	Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine
YP_001211993.1	DegS and COG3920
YP_001211994.1	containing a CheY-like receiver domain and an HTH DNA-binding domain
YP_001211998.1	contains TPR repeats
YP_001212000.1	containing a CheY-like receiver domain and an HTH DNA-binding domain
YP_001212001.1	involved in archaeal flagella biosynthesis
YP_001212016.1	involved in cell wall biogenesis
YP_001212021.1	RecA-mediated autopeptidases
YP_001212031.1	containing ISOPREN_C2_like domain contains class II terpene cyclases, protein prenyltransferases beta subunit
YP_001212033.1	containing ISOPREN_C2_like domain and SLH, S-layer homology domain
YP_001212043.1	involved in propionate catabolism
YP_001212045.1	with DUF1446
YP_001212048.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_001212054.1	regulator of disulfide bond formation
YP_001212057.1	NDP forming
YP_001212059.1	involved in aromatic compounds catabolism
YP_001212060.1	the alpha/beta superfamily
YP_001212068.1	related to tRNA (uracil-5-)-methyltransferase
YP_001212070.1	with duplicated ATPase domains
YP_001212085.1	XdhC/CoxF family
YP_001212108.1	sigma24 homolog
YP_001212121.1	containing transposase_8, transposase.
YP_001212134.1	containing PutA (COG1012), NAD-dependent aldehyde dehydrogenases and EutG (COG1454) alcohol dehydrogenase class IV
YP_001212137.1	containing partial Alpha-amylase/alpha-mannosidase (COG1449)
YP_001212146.1	containing COG2206, HD-GYP domain and COG2203, FhlA, FOG: GAF domain
YP_001212147.1	containing COG3852 NtrB, signal transduction histidine kinase and COG3706 PleD, response regulator containing a CheY-like receiver domain and a GGDEF domain
YP_001212148.1	AP superfamily
YP_001212149.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
YP_001212151.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_001212155.1	containing Exo70, Exo70 exocyst complex subunit domain
YP_001212157.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_001212159.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_001212160.1	related to NifB/MoaA family
YP_001212169.1	these proteins appear to have resulted from a fusion of lytB and rpsA; catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_001212170.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_001212172.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate
YP_001212174.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_001212175.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
YP_001212176.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001212191.1	required for spore maturation
YP_001212192.1	containing GIDA domain
YP_001212201.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
YP_001212204.1	with CbiNQ forms the ABC transporter for cobalt import
YP_001212213.1	containing COG2202, AtoS, FOG: PAS/PAC domain, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain, and HDc, Metal dependent phosphohydrolases with conserved 'HD' motif.
YP_001212214.1	contains helicase and exonuclease domains
YP_001212220.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001212229.1	Heat shock-induced
YP_001212238.1	TIM-barrel fold
YP_001212240.1	with chaperone activity
YP_001212244.1	plays a role in hydrogenase nickel cofactor insertion
YP_001212245.1	involved in chromosome partitioning
YP_001212254.1	NrfD perticipates in the transfer of electrons from quinone pool into the therminal components
YP_001212257.1	distantly related to archaeal holliday junction resolvase
YP_001212258.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_001212261.1	containing partial COG3383, Uncharacterized anaerobic dehydrogenase
YP_001212264.1	Transmembrane regions, NrfD perticipates in the transfer of electrons
YP_001212268.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_001212269.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_001212272.1	contains KH domain
YP_001212273.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_001212275.1	containing partial uncharacterized conserved region in bacteria (COG2739)
YP_001212277.1	containing FOG:GGDEF domain (COG2199) and ResE, FOG: HAMP domain (COG2770)
YP_001212279.1	catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine
YP_001212280.1	eIF-2B alpha/beta/delta family
YP_001212281.1	Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate
YP_001212284.1	containing PspE, rhodanese-related sulfurtransferase (COG0607)
YP_001212285.1	regulator of disulfide bond formation
YP_001212288.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_001212292.1	related to short-chain alcohol dehydrogenases
YP_001212296.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_001212297.1	negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria
YP_001212298.1	possibly nucleic acid-binding protein
YP_001212300.1	NDP forming
YP_001212305.1	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YP_001212306.1	containing Small acid-soluble spore proteins domain
YP_001212307.1	catalyzes branch migration in Holliday junction intermediates
YP_001212308.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_001212309.1	COG0807 RibA and COG0108 RibB
YP_001212310.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_001212311.1	COG1985 and COG0117, riboflavin biosynthesis
YP_001212312.1	containing partial Tar (COG0840), methyl-accepting chemotaxis protein
YP_001212316.1	flavoproteins
YP_001212322.1	containing PAS, AAA-type ATPase, and DNA-binding domains
YP_001212325.1	containing predicted kinase (COG4639) and calcineurin-like phosphoesterase domain
YP_001212328.1	containing NtrB (COG3852), signal transduction histidine kinase
YP_001212331.1	COG0515, SPS1, containing uncharacterized protein conserved in bacteria (COG2815)
YP_001212335.1	containing forkhead associated domain (FHA)
YP_001212336.1	containing forkhead associated domain (FHA) (COG1716)
YP_001212345.1	Essential for recycling GMP and indirectly, cGMP
YP_001212349.1	catalyzes the formation of LL-diaminopimelate from tetrahydrodipicolinate; involved in lysine and peptidoglycan synthesis
YP_001212350.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_001212353.1	Partial COG1293, predicted RNA binding protein homologous to eukaryotic snRNP
YP_001212354.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001212356.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits
YP_001212358.1	containing MGS_CPS_II domain
YP_001212362.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_001212363.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
YP_001212364.1	containing partial predicted polymerase (COG1315)
YP_001212368.1	23S RNA-specific
YP_001212369.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_001212370.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_001212373.1	containing ADP-ribose pyrophosphatase region (COG1051)
YP_001212377.1	containing partial COG1799, Uncharacterized protein conserved in bacteria
YP_001212378.1	TIM-barrel fold
YP_001212381.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001212383.1	the beta-lactamase fold involved in RNA processing
YP_001212385.1	containing LysM domain
YP_001212388.1	containing Spore_GerAC domain (pfam05504)
YP_001212389.1	containing spore permease (pfam03845)
YP_001212390.1	containing GerA domain (pfam03323)
YP_001212392.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_001212393.1	consists of a Zn-ribbon and ATP-cone domains
YP_001212395.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin
YP_001212396.1	sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation
YP_001212397.1	pfam03419
YP_001212400.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_001212401.1	involved in cell division
YP_001212402.1	small basic protein
YP_001212409.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_001212410.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_001212411.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_001212413.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_001212414.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_001212417.1	with 2x PASTA domain
YP_001212419.1	involved in cell envelope biogenesis
YP_001212422.1	catalyzes the formation of L-histidinol from L-histidinol phosphate
YP_001212430.1	containing CDA1 region (COG0726)
YP_001212433.1	typically periplasmic, contain C-terminal PDZ domain
YP_001212435.1	containing predicted ATP-dependent protease (COG1067 LonB)
YP_001212438.1	containing partial COG4120, ABC-type uncharacterized transport system, permease component
YP_001212442.1	containing Tra5 partial region
YP_001212447.1	containing partial Tra8, transposase and inactivated derivatives, IS30 family (COG2826)
YP_001212448.1	predicted ATPase
YP_001212451.1	containing transposase partial region
YP_001212454.1	containing transposase partial region
YP_001212457.1	containing interrase core dimain COG2801
YP_001212458.1	predicted ATPase
YP_001212463.1	involved in DNA repair
YP_001212464.1	involved in DNA repair
YP_001212468.1	involved in DNA repair
YP_001212471.1	predicted to be involved in DNA repair (RAMP superfamily)
YP_001212472.1	predicted to be involved in DNA repair (RAMP superfamily)
YP_001212473.1	predicted to be involved in DNA repair (RAMP superfamily)
YP_001212474.1	predicted to be involved in DNA repair
YP_001212475.1	predicted to be involved in DNA repair (RAMP superfamily)
YP_001212476.1	predicted to be involved in DNA repair (RAMP superfamily)
YP_001212477.1	predicted to be involved in DNA repair (RAMP superfamily)
YP_001212478.1	HD superfamily (permuted catalytic motifs)
YP_001212481.1	containing DNA-binding HTH domain-containing proteins COG2771 CsgD, DNA-binding HTH domain-containing proteins
YP_001212485.1	penicillin-binding protein
YP_001212489.1	MutS family
YP_001212497.1	DNA polymerase IV (family X) and COG1387 HIS2, histidinol phosphatase and related hydrolases of the PHP family
YP_001212500.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_001212503.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_001212505.1	IF-3
YP_001212506.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_001212510.1	with chaperone function
YP_001212520.1	containing partial COG4071, uncharacterized protein conserved in archaea
YP_001212531.1	containing partial MltE (COG0741), Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
YP_001212532.1	involved in spore germination
YP_001212535.1	catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine
YP_001212539.1	involved in DNA repair
YP_001212540.1	involved in DNA repair
YP_001212541.1	involved in DNA repair
YP_001212554.1	containing AtoS (COG2202), FOG: PAS/PAC domain, PAS domain, GGDEF, Diguanylate-cyclase (DGC) and HDc domain, Metal dependent phosphohydrolases with conserved 'HD' motif.
YP_001212559.1	involved in regulation of expression and maturation of urease and hydrogenase
YP_001212560.1	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit, chain G
YP_001212569.1	SIR2 family
YP_001212578.1	AAA+ superfamily
YP_001212583.1	including yeast histone deacetylase and acetoin utilization protein
YP_001212585.1	ClpP class
YP_001212586.1	distant homolog of PhoU
YP_001212588.1	isoleucine patch superfamily
YP_001212591.1	containing a CheY-like receiver domain and an HTH DNA-binding domain
YP_001212610.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_001212613.1	inhibitor of MCP methylation
YP_001212615.1	stimulates methylation of MCP proteins
YP_001212620.1	involved in chromosome partitioning
YP_001212621.1	positive regulator of class III flagellar genes
YP_001212622.1	membrane protein involved in the flagellar export apparatus
YP_001212624.1	FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus
YP_001212626.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_001212639.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_001212647.1	binds to flagellin and appears to stabilize flagellin during flagella assembly
YP_001212648.1	could also regulate swarming and quorum sensing
YP_001212653.1	distantly related to archaeal holliday junction resolvase and Mrr-like restriction enzymes
YP_001212661.1	with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook
YP_001212662.1	with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook
YP_001212664.1	anti-sigma28 factor
YP_001212665.1	containing a CheY-like receiver domain and a methylesterase domain
YP_001212674.1	small heat shock protein
YP_001212689.1	predicted ATPase
YP_001212690.1	containing partial COG3316, transposase and inactivated derivatives
YP_001212704.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_001212706.1	archaeal type
YP_001212709.1	containing partial PhoH (COG1702), phosphate starvation-inducible protein PhoH, predicted ATPase
YP_001212714.1	bacterial type
YP_001212717.1	containing partial BirA (COG1654), Biotin operon repressor
YP_001212721.1	with SCP/PR1 domains
YP_001212743.1	containing partial COG5410, Uncharacterized protein conserved in bacteria and partial COG5362, Phage-related terminase
YP_001212748.1	fused to a predicted acetyltransferase domain
YP_001212749.1	involved in chromosome partitioning
YP_001212762.1	homologous to the C-terminal domain of histone macroH2A1
YP_001212769.1	tryptophan RNA-binding attenuator protein; binds leader Trp transcript causing transcription termination
YP_001212770.1	catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.
YP_001212775.1	SpoU class
YP_001212784.1	containing a ferredoxin-like domain
YP_001212787.1	NDP forming
YP_001212789.1	DNA invertase Pin homologs
YP_001212795.1	UPF0236 family
YP_001212807.1	with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism
YP_001212808.1	containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
YP_001212822.1	antagonist of anti-sigma factor
YP_001212823.1	Ser/Thr protein kinase
YP_001212824.1	regulator of sigma subunit
YP_001212826.1	containing SpoIIAA (COG1366), anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
YP_001212831.1	BglX (COG1472) Beta-glucosidase-related glycosidases and DdpX (COG2173) D-alanyl-D-alanine dipeptidase
YP_001212834.1	Fe-S oxidoreductase
YP_001212853.1	contains PIN domain
YP_001212865.1	containing Peptidase family M23/M37.
YP_001212883.1	containing partial SsnA (COG0402), cytosine deaminase and related metal-dependent hydrolases
YP_001212894.1	Fe-S oxidoreductase
YP_001212918.1	Fe-S oxidoreductase
YP_001212920.1	Fe-S oxidoreductase
YP_001212921.1	Fe-S oxidoreductase
YP_001212927.1	containing COG3848, Phosphohistidine swiveling domain
YP_001212937.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001212951.1	metallo-beta-lactamase superfamily
YP_001212953.1	AAA+ superfamily
YP_001212954.1	containing a Zn-ribbon
YP_001212955.1	containing COG3415, transposase and inactivated derivatives domain
YP_001212957.1	containing GloB (COG0491), Zn-dependent hydrolases, including glyoxylases and partial LytE (COG1388), FOG: LysM repeat
YP_001212964.1	containing partial XerD (COG4974), site-specific recombinase XerD
YP_001212965.1	containing integrase core domain
YP_001212966.1	containing partial COG2963, transposase and inactivated derivatives
YP_001212969.1	converts methylaspartate to L-glutamate
YP_001212976.1	containing integrase core domain
YP_001212977.1	predicted ATPase
YP_001212979.1	containing AtoD (COG1788), acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit and partial AtoA (COG2057), acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit
YP_001212980.1	flavoproteins
YP_001212987.1	containing partial COG3547, transposase and inactivated derivatives
YP_001212988.1	containing PAS, AAA-type ATPase, and DNA-binding domains
YP_001212991.1	containing partial HepA (COG0553), superfamily II DNA/RNA helicases, SNF2 family
YP_001212994.1	containing HTH_3 domain
YP_001212995.1	DNA invertase Pin homologs
YP_001212996.1	containing HTH_4 domain
YP_001213000.1	containing XerD (COG4974), site-specific recombinase XerD
YP_001213001.1	containing partial XerD (COG4974), site-specific recombinase XerD
YP_001213007.1	containing partial COG1310, predicted metal-dependent protease of the PAD1/JAB1 superfamily
YP_001213029.1	containing RpsA (COG0539), ribosomal protein S1
YP_001213034.1	containing partial SpoVK (COG0464), ATPase of the AAA+ class
YP_001213056.1	containing partial DnaB (COG0305), replicative DNA helicase
YP_001213057.1	containing RepA_C domain
YP_001213070.1	in Methanococcus jannaschii this protein catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate; functions in alphaketosuberate synthesis which is a precursor in coenzyme B and biotin synthesis
YP_001213071.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001213072.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_001213077.1	contains BRCT domain type II
YP_001213082.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_001213083.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_001213084.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_001213091.1	involved in de novo purine biosynthesis
YP_001213094.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_001213096.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_001213101.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_001213110.1	contains PIN domain
YP_001213112.1	HD superfamily
YP_001213114.1	containing partial COG3609, predicted transcriptional regulator containing the CopG/Arc/MetJ DNA-binding domain
YP_001213117.1	HD superfamily
YP_001213120.1	containing AslB (COG0641), arylsulfatase regulator (Fe-S oxidoreductase)
YP_001213122.1	containing COG0438, RfaG, glycosyltransferase
YP_001213123.1	containing RfaG (COG0438), glycosyltransferase
YP_001213124.1	apparently involved in regulation of cell wall biogenesis
YP_001213130.1	containing COG1215, glycosyltransferases, probably involved in cell wall biogenesis and COG1216, predicted glycosyltransferases domain
YP_001213133.1	containing partial NrfG (COG0457), FOG: TPR repeat
YP_001213138.1	containing COG5278, predicted periplasmic ligand-binding sensor domain.
YP_001213142.1	including glyoxylases
YP_001213144.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_001213149.1	containing partial SleB (COG3773), cell wall hydrolyses involved in spore germination and partial COG3858, predicted glycosyl hydrolase
YP_001213153.1	containing partial COG3695, predicted methylated DNA-protein cysteine methyltransferase
YP_001213155.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_001213156.1	containing COG3547, transposase and inactivated derivatives
YP_001213157.1	HSP10
YP_001213160.1	required for formate dehydrogenase activity
YP_001213161.1	containing 2x S-layer homology domain
YP_001213163.1	containing COG4252, predicted transmembrane sensor domain and partial CyaA (COG2114), Adenylate cyclase, family 3
YP_001213165.1	containing FhlA (COG2203), FOG: GAF domain and partial COG2206, HD-GYP domain
YP_001213166.1	COG0303, MoeA, containing Periplasmic molybdate-binding domain (COG1910)
YP_001213169.1	involved in molybdopterin and thiamine biosynthesis family 2
YP_001213172.1	containing partial COG2258, Uncharacterized protein conserved in bacteria
YP_001213189.1	containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
YP_001213190.1	containing FhlA (COG2203), FOG: GAF domain and partial COG4191, signal transduction histidine kinase regulating C4-dicarboxylate transport system
YP_001213191.1	class IV
YP_001213193.1	containing partial CDA1 (COG0726), predicted xylanase/chitin deacetylase
YP_001213194.1	containing partial COG1139, uncharacterized conserved protein containing a ferredoxin-like domain
YP_001213195.1	containing partial COG3383, Uncharacterized anaerobic dehydrogenase
YP_001213196.1	containing partial COG3383, Uncharacterized anaerobic dehydrogenase
YP_001213197.1	containing partial NuoG (COG1034), NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)
YP_001213204.1	containing partial NrdG (COG0602), organic radical activating enzymes
YP_001213205.1	with possible chaperone activity
YP_001213209.1	containing XerD (COG4974), site-specific recombinase XerD
YP_001213211.1	containing ASC domain
YP_001213212.1	homolog of Drosophila rhomboid
YP_001213214.1	SIR2 family
YP_001213215.1	PP-loop superfamily implicated in cell cycle control
YP_001213220.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_001213225.1	containing partial Spr (COG0791), Cell wall-associated hydrolases (invasion-associated proteins)
YP_001213229.1	containing COG1655, Uncharacterized protein conserved in bacteria and partial Crp (COG0664), cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
YP_001213235.1	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
YP_001213236.1	related to aryl-alcohol dehydrogenases
YP_001213237.1	including glyoxylases
YP_001213239.1	beta-lactamase fold
YP_001213247.1	containing HDc, Metal dependent phosphohydrolases with conserved 'HD' motif.
YP_001213248.1	contains PIN domain
YP_001213256.1	containing 4Fe-4S binding domain.
YP_001213257.1	typically selenocysteine-containing
YP_001213262.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_001213263.1	containing integrase core domain
YP_001213264.1	HD superfamily
YP_001213265.1	containing PaaI (COG2050), Uncharacterized protein, possibly involved in aromatic compounds catabolism
YP_001213266.1	pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient
YP_001213269.1	containing Eno (COG0148), Enolase
YP_001213270.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_001213276.1	containing LbetaH domain
YP_001213285.1	HAD superfamily
YP_001213286.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_001213288.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_001213293.1	containing PDZ domain
YP_001213297.1	involved in cell division
YP_001213303.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_001213304.1	PSrp-1
YP_001213307.1	containing FOG (COG2199): GGDEF domain and FhlA (COG2203), FOG: GAF domain
YP_001213311.1	putative virulence factor
YP_001213320.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_001213322.1	containing glycosyl transferases group 1 domain
YP_001213328.1	containing partial WcaK (COG2327), uncharacterized conserved protein
YP_001213333.1	contains PIN domain
YP_001213334.1	containing HTH_4 domain
YP_001213341.1	containing partial COG4710, predicted DNA-binding protein with an HTH domain
YP_001213342.1	contains PIN domain
YP_001213346.1	contains PIN domain
YP_001213347.1	containing S-layer homology domain
YP_001213348.1	containing Peptidase_S8, Subtilase family
YP_001213349.1	involved in cell morphogenesis
YP_001213352.1	containing partial CcmA (COG1131), ABC-type multidrug transport system, ATPase component
YP_001213355.1	containing 3 x S-layer homology (SLH) domain and partial COG4886, Leucine-rich repeat (LRR) protein
YP_001213356.1	containing effector domain of the CAP family of transcription factors, Sigma-54 interaction domain and partial NapH (COG0348), Polyferredoxin
YP_001213357.1	containing PIN domain
YP_001213361.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex
YP_001213362.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_001213363.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_001213364.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_001213365.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_001213372.1	containing partial MazG (COG1694), predicted pyrophosphatase
YP_001213374.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_001213382.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_001213384.1	related to metalloendopeptidases
YP_001213385.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_001213388.1	class II aldolase; catalyzes the formation of fructose 1,6-bisphosphate from dihydroxyacetone phosphate and glyceraldehyde 3-phosphate
YP_001213392.1	ClpP class
YP_001213393.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_001213394.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_001213403.1	containing partial SleB (COG3773), cell wall hydrolyses involved in spore germination
YP_001213410.1	containing partial COG4235, Cytochrome c biogenesis factor
YP_001213411.1	related to metalloendopeptidases
YP_001213416.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001213419.1	containing PAS domain and two FhlA (COG2203), FOG: GAF domain and partial AtoS (COG2202), FOG: PAS/PAC domain
YP_001213427.1	containing partial RepA (COG3598), RecA-family ATPase
YP_001213433.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_001213437.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_001213440.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_001213442.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_001213443.1	containing partial AraJ (COG2814), arabinose efflux permease and partial UhpC (COG2271), sugar phosphate permease
YP_001213444.1	related to short-chain alcohol dehydrogenases
YP_001213446.1	class IV
YP_001213448.1	involved in thiamine biosynthesis
YP_001213454.1	catalyzes the removal of amino acids from the N termini of peptides
YP_001213456.1	required for colicin V production
YP_001213458.1	containing DUF1256, Protein of unknown function (DUF1256)
YP_001213459.1	UPF0180
YP_001213462.1	possible Na+ channel or pump
YP_001213464.1	involved in chromosome partitioning
YP_001213465.1	involved in bacterial cell division
YP_001213466.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_001213467.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE