-- dump date 20140619_233901 -- class Genbank::misc_feature -- table misc_feature_note -- id note 291112000002 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112000003 active site 291112000004 DNA binding site [nucleotide binding] 291112000005 Int/Topo IB signature motif; other site 291112000006 HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 2.3e-07 291112000007 4 probable transmembrane helices predicted for pPA0004 by TMHMM2.0 at aa 13-35, 67-88, 108-127 and 154-176 291112000008 Colicin pore forming domain; Region: Colicin; pfam01024 291112000009 HMMPfam hit to PF01024, Channel forming colicin, C-terminal cytotoxic, score 3e-60 291112000010 1 probable transmembrane helix predicted for pPA0005 by TMHMM2.0 at aa 387-409 291112000011 ParA-like protein; Provisional; Region: PHA02518 291112000012 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 291112000013 P-loop; other site 291112000014 Magnesium ion binding site [ion binding]; other site 291112000015 2 probable transmembrane helices predicted for pPA0009 by TMHMM2.0 at aa 53-72 and 79-101 291112000016 Protein of unknown function (DUF1778); Region: DUF1778; pfam08681 291112000017 HMMPfam hit to PF08681, Protein of unknown function DUF1778, score 4.2e-26 291112000018 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112000019 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 291112000020 Coenzyme A binding pocket [chemical binding]; other site 291112000021 HMMPfam hit to PF00583, GCN5-related N-acetyltransferase, score 4.7e-05 291112000022 virion protein; Provisional; Region: V; PHA02564 291112000023 1 probable transmembrane helix predicted for pPA0013 by TMHMM2.0 at aa 205-227 291112000024 1 probable transmembrane helix predicted for pPA0017 by TMHMM2.0 at aa 96-118 291112000025 multiple promoter invertase; Provisional; Region: mpi; PRK13413 291112000026 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 291112000027 catalytic residues [active] 291112000028 catalytic nucleophile [active] 291112000029 Presynaptic Site I dimer interface [polypeptide binding]; other site 291112000030 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 291112000031 Synaptic Flat tetramer interface [polypeptide binding]; other site 291112000032 Synaptic Site I dimer interface [polypeptide binding]; other site 291112000033 DNA binding site [nucleotide binding] 291112000034 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 291112000035 DNA-binding interface [nucleotide binding]; DNA binding site 291112000036 HMMPfam hit to PF00239, Resolvase, N-terminal, score 1.7e-58 291112000037 KilA-N domain; Region: KilA-N; pfam04383 291112000038 Phage-related protein, tail component [Function unknown]; Region: COG4733 291112000039 Putative phage tail protein; Region: Phage-tail_3; pfam13550 291112000040 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 291112000041 Domain of unknown function (DUF1983); Region: DUF1983; pfam09327 291112000042 HMMPfam hit to PF09327, Protein of unknown function DUF1983, score 5e-37 291112000043 HMMPfam hit to PF00041, Fibronectin, type III, score 0.0049 291112000044 Phage-related protein, tail component [Function unknown]; Region: COG4723 291112000045 HMMPfam hit to PF06805, Bacteriophage lambda tail assembly I, score 5.5e-51 291112000046 2 probable transmembrane helices predicted for pPA0021 by TMHMM2.0 at aa 111-130 and 135-157 291112000047 Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073 291112000048 MPN+ (JAMM) motif; other site 291112000049 Zinc-binding site [ion binding]; other site 291112000050 Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791 291112000051 NlpC/P60 family; Region: NLPC_P60; pfam00877 291112000052 HMMPfam hit to PF00877, NLP/P60, score 1.3e-29 291112000053 Phage minor tail protein L; Region: Phage_tail_L; cl01908 291112000054 HMMPfam hit to PF05100, Phage minor tail protein L, score 2.7e-116 291112000055 Phage minor tail protein; Region: Phage_min_tail; cl01940 291112000056 HMMPfam hit to PF05939, Phage minor tail, score 3.1e-33 291112000057 Mu-like prophage protein [General function prediction only]; Region: COG3941 291112000058 tape measure domain; Region: tape_meas_nterm; TIGR02675 291112000059 Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718 291112000060 2 probable transmembrane helices predicted for pPA0025 by TMHMM2.0 at aa 499-518 and 590-612 291112000062 chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362 291112000063 DnaA N-terminal domain; Region: DnaA_N; pfam11638 291112000064 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112000065 Walker A motif; other site 291112000066 ATP binding site [chemical binding]; other site 291112000067 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189 291112000068 Walker B motif; other site 291112000069 arginine finger; other site 291112000070 C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571 291112000071 DnaA box-binding interface [nucleotide binding]; other site 291112000072 HMMPfam hit to PF00308, Bacterial dnaA protein, score 4.1e-151 291112000073 HMMSmart hit to SM00382, no description, score 2.4e-07 291112000074 HMMPfam hit to PF08299, Bacterial dnaA protein helix-turn-helix, score 1.9e-48 291112000075 DNA polymerase III subunit beta; Validated; Region: PRK05643 291112000076 Beta clamp domain. The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria. The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140 291112000077 putative DNA binding surface [nucleotide binding]; other site 291112000078 dimer interface [polypeptide binding]; other site 291112000079 beta-clamp/clamp loader binding surface; other site 291112000080 beta-clamp/translesion DNA polymerase binding surface; other site 291112000081 HMMPfam hit to PF00712, DNA polymerase III beta subunit, N-te, score 1.3e-63 291112000082 HMMSmart hit to SM00480, no description, score 5e-161 291112000083 HMMPfam hit to PF02767, DNA polymerase III beta subunit, cent, score 1.1e-65 291112000084 HMMPfam hit to PF02768, DNA polymerase III beta subunit, C-te, score 2.4e-60 291112000085 recF protein; Region: recf; TIGR00611 291112000086 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112000087 Walker A/P-loop; other site 291112000088 ATP binding site [chemical binding]; other site 291112000089 Q-loop/lid; other site 291112000090 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112000091 ABC transporter signature motif; other site 291112000092 Walker B; other site 291112000093 D-loop; other site 291112000094 H-loop/switch region; other site 291112000095 HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 4.1e-55 291112000096 DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939 291112000097 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112000098 Mg2+ binding site [ion binding]; other site 291112000099 G-X-G motif; other site 291112000100 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 291112000101 anchoring element; other site 291112000102 dimer interface [polypeptide binding]; other site 291112000103 ATP binding site [chemical binding]; other site 291112000104 TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366 291112000105 active site 291112000106 putative metal-binding site [ion binding]; other site 291112000107 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 291112000108 HMMSmart hit to SM00387, no description, score 3.2e-30 291112000109 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 4.2e-33 291112000110 HMMSmart hit to SM00433, no description, score 1.4e-285 291112000111 HMMPfam hit to PF00204, DNA gyrase B, score 1e-93 291112000112 HMMPfam hit to PF01751, Toprim domain, score 1.1e-05 291112000113 HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 6.1e-46 291112000114 aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598 291112000115 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 291112000116 HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisat, score 2.7e-77 291112000117 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindi, score 6.2e-36 291112000118 DNA-binding transcriptional regulator; Provisional; Region: PRK09678 291112000119 Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606 291112000120 HMMPfam hit to PF04606, Ogr/Delta-like zinc finger, score 9.5e-27 291112000121 tail protein; Provisional; Region: D; PHA02561 291112000122 HMMPfam hit to PF05954, Phage late control gene D protein (GPD), score 3.8e-163 291112000123 Phage P2 GpU; Region: Phage_P2_GpU; pfam06995 291112000124 HMMPfam hit to PF06995, Phage P2 GpU, score 4.1e-61 291112000125 phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760 291112000126 HMMPfam hit to PF05017, no description, score 40 291112000127 HMMPfam hit to PF05017, no description, score 2.1e+02 291112000128 HMMPfam hit to PF05017, no description, score 1.4 291112000129 HMMPfam hit to PF05017, no description, score 44 291112000130 HMMPfam hit to PF05017, no description, score 1e+02 291112000131 3 probable transmembrane helices predicted for PAT2041 by TMHMM2.0 at aa 500-522, 537-557 and 570-592 291112000132 Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109 291112000133 HMMPfam hit to PF06158, Phage tail protein E, score 2e-37 291112000134 Phage tail tube protein FII; Region: Phage_tube; pfam04985 291112000135 HMMPfam hit to PF04985, Phage tail tube protein FII, score 7.2e-98 291112000136 major tail sheath protein; Provisional; Region: FI; PHA02560 291112000137 HMMPfam hit to PF04984, Phage tail sheath protein, score 2.7e-175 291112000138 Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675 291112000139 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112000140 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 9.7e-43 291112000141 Phage Tail Collar Domain; Region: Collar; pfam07484 291112000142 Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675 291112000143 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 2.8e-21 291112000144 Phage tail-collar fibre protein; Region: DUF3751; pfam12571 291112000145 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112000146 Phage Tail Collar Domain; Region: Collar; pfam07484 291112000147 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 4.9e-23 291112000148 HMMPfam hit to PF03406, Phage tail fibre repeat, score 1.3e-15 291112000149 Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385 291112000150 Baseplate J-like protein; Region: Baseplate_J; cl01294 291112000151 HMMPfam hit to PF04865, Baseplate J-like protein, score 9e-81 291112000152 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 291112000153 HMMPfam hit to PF04965, GPW / gp25 family, score 6.3e-37 291112000154 phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644 291112000155 Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540 291112000156 HMMPfam hit to PF04717, Phage-related baseplate assembly protein, score 2.1e-49 291112000157 Phage Tail Protein X; Region: Phage_tail_X; pfam05489 291112000158 HMMPfam hit to PF05489, Phage Tail Protein X, score 8e-25 291112000159 Predicted transcriptional regulator [Transcription]; Region: COG2932 291112000160 Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022 291112000161 HMMPfam hit to PF07022, Bacteriophage CI repressor helix-turn-h, score 1.4e-39 291112000162 Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961 291112000163 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 291112000164 catalytic residues [active] 291112000165 catalytic nucleophile [active] 291112000166 Presynaptic Site I dimer interface [polypeptide binding]; other site 291112000167 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 291112000168 Synaptic Flat tetramer interface [polypeptide binding]; other site 291112000169 Synaptic Site I dimer interface [polypeptide binding]; other site 291112000170 DNA binding site [nucleotide binding] 291112000171 Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569 291112000172 DNA-binding interface [nucleotide binding]; DNA binding site 291112000173 HMMPfam hit to PF02796, Helix-turn-helix domain of resolvase, score 3.5e-09 291112000174 HMMPfam hit to PF00239, Resolvase, N terminal domain, score 2e-74 291112000175 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112000176 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 3.1e-32 291112000177 Phage Tail Collar Domain; Region: Collar; pfam07484 291112000178 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 1.9e-21 291112000179 50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831 291112000180 HMMPfam hit to PF00444, Ribosomal protein L36, score 0.00015 291112000181 50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678 291112000182 HMMPfam hit to PF01197, Ribosomal protein L31, score 3.5e-10 291112000183 1 probable transmembrane helix predicted for PAT2064 by TMHMM2.0 at aa 35-57 291112000184 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 291112000185 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 291112000186 glutaminase active site [active] 291112000187 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 291112000188 dimer interface [polypeptide binding]; other site 291112000189 active site 291112000190 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 291112000191 dimer interface [polypeptide binding]; other site 291112000192 active site 291112000193 HMMPfam hit to PF01380, SIS domain, score 5.8e-35 291112000194 HMMPfam hit to PF01380, SIS domain, score 1.6e-39 291112000195 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 8.1e-51 291112000196 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451 291112000197 N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540 291112000198 Substrate binding site; other site 291112000199 Mg++ binding site; other site 291112000200 N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353 291112000201 active site 291112000202 substrate binding site [chemical binding]; other site 291112000203 CoA binding site [chemical binding]; other site 291112000204 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 2.4 291112000205 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 2.3 291112000206 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 1.1e+02 291112000207 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 21 291112000208 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.039 291112000209 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (th, score 0.14 291112000210 HMMPfam hit to PF00483, Nucleotidyl transferase, score 6.4e-08 291112000211 F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571 291112000212 mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152 291112000213 gamma subunit interface [polypeptide binding]; other site 291112000214 epsilon subunit interface [polypeptide binding]; other site 291112000215 LBP interface [polypeptide binding]; other site 291112000216 HMMPfam hit to PF00401, ATP synthase, Delta/Epsilon chain, long, score 1.1e-12 291112000217 HMMPfam hit to PF02823, ATP synthase, Delta/Epsilon chain, beta, score 4.3e-32 291112000218 F0F1 ATP synthase subunit beta; Validated; Region: PRK09280 291112000219 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 291112000220 F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133 291112000221 alpha subunit interaction interface [polypeptide binding]; other site 291112000222 Walker A motif; other site 291112000223 ATP binding site [chemical binding]; other site 291112000224 Walker B motif; other site 291112000225 inhibitor binding site; inhibition site 291112000226 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 291112000227 HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 4e-49 291112000228 HMMSmart hit to SM00382, no description, score 0.0003 291112000229 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 1.9e-91 291112000230 HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 6.1e-25 291112000231 mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151 291112000232 core domain interface [polypeptide binding]; other site 291112000233 delta subunit interface [polypeptide binding]; other site 291112000234 epsilon subunit interface [polypeptide binding]; other site 291112000235 HMMPfam hit to PF00231, ATP synthase, score 6.7e-166 291112000236 F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281 291112000237 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 291112000238 F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132 291112000239 beta subunit interaction interface [polypeptide binding]; other site 291112000240 Walker A motif; other site 291112000241 ATP binding site [chemical binding]; other site 291112000242 Walker B motif; other site 291112000243 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 291112000244 HMMPfam hit to PF00306, ATP synthase alpha/beta chain, C termin, score 1.4e-27 291112000245 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 6e-117 291112000246 HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 1.1e-16 291112000247 F0F1 ATP synthase subunit delta; Validated; Region: PRK05758 291112000248 ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213 291112000249 HMMPfam hit to PF00213, ATP synthase delta (OSCP) subunit, score 3.5e-70 291112000250 F0F1 ATP synthase subunit B; Validated; Region: PRK05759 291112000251 F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711 291112000252 HMMPfam hit to PF00430, ATP synthase B/B' CF(0), score 4.1e-40 291112000253 1 probable transmembrane helix predicted for PAT2072 by TMHMM2.0 at aa 7-29 291112000254 F0F1 ATP synthase subunit C; Validated; Region: PRK06876 291112000255 HMMPfam hit to PF00137, ATP synthase subunit C, score 1.2e-24 291112000256 2 probable transmembrane helices predicted for PAT2073 by TMHMM2.0 at aa 10-32 and 53-75 291112000257 F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356 291112000258 F0F1 ATP synthase subunit A; Validated; Region: PRK05815 291112000259 HMMPfam hit to PF00119, ATP synthase A chain, score 6.6e-92 291112000260 5 probable transmembrane helices predicted for PAT2074 by TMHMM2.0 at aa 41-63, 103-125, 145-167, 214-236 and 246-268 291112000261 F0F1 ATP synthase subunit I; Validated; Region: PRK08049 291112000262 HMMPfam hit to PF03899, ATP synthase I chain, score 3.5e-20 291112000263 4 probable transmembrane helices predicted for PAT2075 by TMHMM2.0 at aa 10-29, 36-58, 73-95 and 102-124 291112000264 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357 291112000265 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112000266 S-adenosylmethionine binding site [chemical binding]; other site 291112000267 HMMPfam hit to PF02527, Glucose inhibited division protein, score 1.9e-83 291112000268 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192 291112000269 NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206 291112000270 GidA associated domain 3; Region: GIDA_assoc_3; pfam13932 291112000271 HMMPfam hit to PF01134, Glucose inhibited division protein A, score 6.7e-273 291112000272 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0011 291112000273 FMN-binding protein MioC; Provisional; Region: PRK09004 291112000274 HMMPfam hit to PF00258, Flavodoxin, score 1.7e-35 291112000275 DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179 291112000276 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 291112000277 putative DNA binding site [nucleotide binding]; other site 291112000278 putative Zn2+ binding site [ion binding]; other site 291112000279 AsnC family; Region: AsnC_trans_reg; pfam01037 291112000280 HMMPfam hit to PF01037, AsnC family, score 3.2e-19 291112000281 HMMSmart hit to SM00344, no description, score 3.3e-44 291112000282 Asparagine synthetase A [Amino acid transport and metabolism]; Region: AsnA; COG2502 291112000283 motif 1; other site 291112000284 dimer interface [polypeptide binding]; other site 291112000285 active site 291112000286 motif 2; other site 291112000287 motif 3; other site 291112000288 HMMPfam hit to PF03590, Aspartate-ammonia ligase, score 7.2e-167 291112000289 hypothetical protein; Provisional; Region: yieM; PRK10997 291112000290 VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462 291112000291 metal ion-dependent adhesion site (MIDAS); other site 291112000292 HMMSmart hit to SM00327, no description, score 5.2e-05 291112000293 regulatory ATPase RavA; Provisional; Region: PRK13531 291112000294 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112000295 Walker A motif; other site 291112000296 ATP binding site [chemical binding]; other site 291112000297 Walker B motif; other site 291112000298 arginine finger; other site 291112000299 Protein of unknown function (DUF3763); Region: DUF3763; pfam12592 291112000300 HMMSmart hit to SM00382, no description, score 3.6e-05 291112000301 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 1.4e-42 291112000302 D-ribose pyranase; Provisional; Region: PRK11797 291112000303 HMMPfam hit to PF05025, RbsD / FucU transport protein family, score 2.8e-63 291112000304 D-ribose transporter ATP binding protein; Provisional; Region: PRK10762 291112000305 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 291112000306 Walker A/P-loop; other site 291112000307 ATP binding site [chemical binding]; other site 291112000308 Q-loop/lid; other site 291112000309 ABC transporter signature motif; other site 291112000310 Walker B; other site 291112000311 D-loop; other site 291112000312 H-loop/switch region; other site 291112000313 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 291112000314 HMMSmart hit to SM00382, no description, score 9.9e-08 291112000315 HMMPfam hit to PF00005, ABC transporter, score 5.6e-48 291112000316 HMMSmart hit to SM00382, no description, score 1.2e-10 291112000317 HMMPfam hit to PF00005, ABC transporter, score 1.8e-34 291112000318 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 291112000319 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 291112000320 TM-ABC transporter signature motif; other site 291112000321 7 probable transmembrane helices predicted for PAT2085 by TMHMM2.0 at aa 25-44, 56-78, 98-120, 127-146, 171-193, 222-244 and 276-298 291112000322 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 6.1e-76 291112000323 D-ribose transporter subunit RbsB; Provisional; Region: PRK10653 291112000324 Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323 291112000325 ligand binding site [chemical binding]; other site 291112000326 dimerization interface [polypeptide binding]; other site 291112000327 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.9e-09 291112000328 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 291112000329 Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174 291112000330 substrate binding site [chemical binding]; other site 291112000331 dimer interface [polypeptide binding]; other site 291112000332 ATP binding site [chemical binding]; other site 291112000333 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 8.6e-89 291112000334 HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase, score 9.5e-05 291112000335 transcriptional repressor RbsR; Provisional; Region: PRK10423 291112000336 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 291112000337 DNA binding site [nucleotide binding] 291112000338 domain linker motif; other site 291112000339 Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275 291112000340 dimerization interface [polypeptide binding]; other site 291112000341 ligand binding site [chemical binding]; other site 291112000342 HMMSmart hit to SM00354, no description, score 2.1e-33 291112000343 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 1.2e-12 291112000344 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 2.3e-17 291112000345 putative transporter; Provisional; Region: PRK10504 291112000346 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112000347 14 probable transmembrane helices predicted for PAT2089 by TMHMM2.0 at aa 13-35, 50-69, 76-98, 102-124, 136-158, 162-181, 194-213, 223-242, 263-285, 290-312, 324-346, 351-373, 394-416 and 431-450 291112000348 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.8e-49 291112000349 lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598 291112000350 Sulfatase; Region: Sulfatase; pfam00884 291112000351 HMMPfam hit to PF00884, Sulfatase, score 3.9e-49 291112000352 5 probable transmembrane helices predicted for PAT2096 by TMHMM2.0 at aa 7-26, 30-47, 54-73, 107-126 and 133-155 291112000353 Predicted symporter [General function prediction only]; Region: DhlC; COG4147 291112000354 Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480 291112000355 Na binding site [ion binding]; other site 291112000356 14 probable transmembrane helices predicted for PAT2097 by TMHMM2.0 at aa 5-22, 32-54, 75-97, 102-124, 145-167, 182-204, 211-233, 263-285, 297-319, 361-383, 404-423, 428-450, 462-484 and 494-516 291112000357 HMMPfam hit to PF00474, Sodium:solute symporter family, score 3.2e-173 291112000358 Predicted membrane protein [Function unknown]; Region: COG3162 291112000359 HMMPfam hit to PF04341, Protein of unknown function, DUF485, score 5e-46 291112000360 2 probable transmembrane helices predicted for PAT2098 by TMHMM2.0 at aa 25-47 and 62-84 291112000361 acetyl-CoA synthetase; Provisional; Region: PRK00174 291112000362 Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966 291112000363 active site 291112000364 CoA binding site [chemical binding]; other site 291112000365 acyl-activating enzyme (AAE) consensus motif; other site 291112000366 AMP binding site [chemical binding]; other site 291112000367 acetate binding site [chemical binding]; other site 291112000368 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.8e-135 291112000369 superoxide dismutase; Provisional; Region: PRK10925 291112000370 Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081 291112000371 Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777 291112000372 HMMPfam hit to PF00081, Iron/manganese superoxide dismutases, alpha-, score 2.7e-48 291112000373 HMMPfam hit to PF02777, Iron/manganese superoxide dismutases, C-term, score 6.1e-63 291112000374 6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536 291112000375 MOSC domain; Region: MOSC; pfam03473 291112000376 3-alpha domain; Region: 3-alpha; pfam03475 291112000377 HMMPfam hit to PF03473, MOSC domain, score 1.3e-44 291112000378 HMMPfam hit to PF03475, 3-alpha domain, score 5.6e-09 291112000379 tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282 291112000380 catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806 291112000381 active site 291112000382 HIGH motif; other site 291112000383 dimer interface [polypeptide binding]; other site 291112000384 KMSKS motif; other site 291112000385 HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 8.2e-119 291112000386 phosphoglycolate phosphatase; Provisional; Region: PRK13222 291112000387 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112000388 motif II; other site 291112000389 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 8.3e-37 291112000390 Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429 291112000391 ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163 291112000392 substrate binding site [chemical binding]; other site 291112000393 hexamer interface [polypeptide binding]; other site 291112000394 metal binding site [ion binding]; metal-binding site 291112000395 HMMPfam hit to PF00834, Ribulose-phosphate 3 epimerase family, score 8.5e-140 291112000396 DNA adenine methylase; Provisional; Region: PRK10904 291112000397 HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA met, score 3.2e-97 291112000398 hypothetical protein; Reviewed; Region: PRK11901 291112000399 cell division protein DamX; Validated; Region: PRK10905 291112000400 cell division protein DamX; Validated; Region: PRK10905 291112000401 HMMPfam hit to PF05036, Sporulation related domain, score 2.4e-09 291112000402 1 probable transmembrane helix predicted for PAT2107 by TMHMM2.0 at aa 52-74 291112000403 Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195 291112000404 active site 291112000405 dimer interface [polypeptide binding]; other site 291112000406 metal binding site [ion binding]; metal-binding site 291112000407 HMMPfam hit to PF01761, 3-dehydroquinate synthase, score 6.9e-184 291112000408 shikimate kinase; Reviewed; Region: aroK; PRK00131 291112000409 Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464 291112000410 ADP binding site [chemical binding]; other site 291112000411 magnesium binding site [ion binding]; other site 291112000412 putative shikimate binding site; other site 291112000413 HMMPfam hit to PF01202, Shikimate kinase, score 1.9e-80 291112000414 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 291112000415 pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519 291112000416 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 291112000417 HMMPfam hit to PF00263, Bacterial type II and III secretion system, score 1.6e-62 291112000418 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 1.4e-07 291112000419 1 probable transmembrane helix predicted for PAT2111 by TMHMM2.0 at aa 15-37 291112000420 Fimbrial assembly protein (PilN); Region: PilN; pfam05137 291112000421 HMMPfam hit to PF05137, Fimbrial assembly protein (PilN), score 1.3e-06 291112000422 1 probable transmembrane helix predicted for PAT2112 by TMHMM2.0 at aa 21-40 291112000423 Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972 291112000424 penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636 291112000425 Transglycosylase; Region: Transgly; pfam00912 291112000426 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 291112000427 1 probable transmembrane helix predicted for PAT2114 by TMHMM2.0 at aa 7-29 291112000428 HMMPfam hit to PF00912, Transglycosylase, score 6.9e-92 291112000429 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 3.5e-22 291112000430 adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762 291112000431 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 291112000432 ADP-ribose binding site [chemical binding]; other site 291112000433 dimer interface [polypeptide binding]; other site 291112000434 active site 291112000435 nudix motif; other site 291112000436 metal binding site [ion binding]; metal-binding site 291112000437 HMMPfam hit to PF00293, NUDIX domain, score 1.2e-14 291112000438 Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095 291112000439 2 probable transmembrane helices predicted for PAT2116 by TMHMM2.0 at aa 167-189 and 199-221 291112000440 Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095 291112000441 HMMPfam hit to PF07095, Intracellular growth attenuator protein IgaA, score 5.5e-52 291112000442 1 probable transmembrane helix predicted for PAT2117 by TMHMM2.0 at aa 312-334 291112000443 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 291112000444 RNA binding surface [nucleotide binding]; other site 291112000445 HMMSmart hit to SM00363, no description, score 2e-09 291112000446 HMMPfam hit to PF01479, S4 domain, score 3.3e-11 291112000447 Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114 291112000448 Heat shock protein 33 (Hsp33): Cytosolic protein that acts as a molecular chaperone under oxidative conditions. In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498 291112000449 dimerization interface [polypeptide binding]; other site 291112000450 domain crossover interface; other site 291112000451 redox-dependent activation switch; other site 291112000452 HMMPfam hit to PF01430, Hsp33 protein, score 2.5e-123 291112000453 Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484 291112000454 Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293 291112000455 active site 291112000456 substrate-binding site [chemical binding]; other site 291112000457 metal-binding site [ion binding] 291112000458 ATP binding site [chemical binding]; other site 291112000459 HMMPfam hit to PF01293, Phosphoenolpyruvate carboxykinase, score 0 291112000460 Pirin-related protein [General function prediction only]; Region: COG1741 291112000461 Pirin-related protein [General function prediction only]; Region: COG1741 291112000462 Pirin; Region: Pirin; pfam02678 291112000463 HMMPfam hit to PF07883, Cupin domain, score 0.0021 291112000464 HMMPfam hit to PF02678, Pirin, score 3.6e-54 291112000465 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112000466 dimer interface [polypeptide binding]; other site 291112000467 phosphorylation site [posttranslational modification] 291112000468 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112000469 ATP binding site [chemical binding]; other site 291112000470 Mg2+ binding site [ion binding]; other site 291112000471 G-X-G motif; other site 291112000472 2 probable transmembrane helices predicted for PAT2123 by TMHMM2.0 at aa 10-32 and 182-204 291112000473 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.0032 291112000474 HMMSmart hit to SM00387, no description, score 1.1e-20 291112000475 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.6e-27 291112000476 Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566 291112000477 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112000478 active site 291112000479 phosphorylation site [posttranslational modification] 291112000480 intermolecular recognition site; other site 291112000481 dimerization interface [polypeptide binding]; other site 291112000482 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112000483 DNA binding residues [nucleotide binding] 291112000484 dimerization interface [polypeptide binding]; other site 291112000485 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.2e-22 291112000486 HMMSmart hit to SM00448, no description, score 3.9e-22 291112000487 HMMPfam hit to PF08281, Sigma-70, region, score 0.0016 291112000488 HMMSmart hit to SM00421, no description, score 6.8e-20 291112000489 Domain of unknown function (DUF336); Region: DUF336; pfam03928 291112000490 HMMPfam hit to PF03928, Domain of unknown function (DUF336), score 1.7e-38 291112000491 Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315 291112000492 carbohydrate binding site [chemical binding]; other site 291112000493 alpha-1,6-glucosidases, pullulanase-type; Region: pullul_strch; TIGR02103 291112000494 Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860 291112000495 Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341 291112000496 Ca binding site [ion binding]; other site 291112000497 active site 291112000498 catalytic site [active] 291112000499 Domain of unknown function (DUF3372); Region: DUF3372; pfam11852 291112000500 HMMPfam hit to PF03714, Bacterial pullanase-associated domain, score 2.9e-22 291112000501 HMMPfam hit to PF02922, Isoamylase N-terminal domain, score 5.5e-14 291112000502 HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 5.9e-07 291112000503 HMMSmart hit to SM00642, no description, score 0.0077 291112000504 cyanate hydratase; Validated; Region: PRK02866 291112000505 Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate. It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559 291112000506 oligomer interface [polypeptide binding]; other site 291112000507 active site 291112000508 HMMPfam hit to PF02560, Cyanate lyase C-terminal domain, score 2.6e-48 291112000509 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 291112000510 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 291112000511 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112000512 Serine hydrolase; Region: Ser_hydrolase; cl17834 291112000513 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.9e-05 291112000514 4 probable transmembrane helices predicted for PAT2132 by TMHMM2.0 at aa 21-43, 53-75, 87-109 and 124-146 291112000515 4 probable transmembrane helices predicted for PAT2132 by TMHMM2.0 at aa 13-35, 50-72, 85-107 and 132-154 291112000516 Domain of unknown function (DUF4143); Region: DUF4143; pfam13635 291112000517 HI0933-like protein; Region: HI0933_like; pfam03486 291112000518 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 291112000519 HMMPfam hit to PF03486, HI0933-like protein, score 1.2e-235 291112000520 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 9.3e-06 291112000521 HMMPfam hit to PF00890, FAD binding domain, score 0.0046 291112000522 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 8.8e-05 291112000523 Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306 291112000524 Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306 291112000525 9 probable transmembrane helices predicted for PAT2135 by TMHMM2.0 at aa 10-32, 52-74, 94-116, 123-145, 155-177, 207-224, 234-256, 376-398 and 470-492 291112000526 HMMPfam hit to PF01384, Phosphate transporter family, score 1.3e-102 291112000527 universal stress protein UspB; Provisional; Region: PRK04960 291112000528 2 probable transmembrane helices predicted for PAT2136 by TMHMM2.0 at aa 10-29 and 102-121 291112000529 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112000530 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 7.4e-62 291112000531 Protein of unknown function (DUF4225); Region: DUF4225; pfam13988 291112000532 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 291112000533 Ligand Binding Site [chemical binding]; other site 291112000534 HMMPfam hit to PF00582, Universal stress protein family, score 3.6e-18 291112000535 glutamate dehydrogenase; Provisional; Region: PRK09414 291112000536 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812 291112000537 NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313 291112000538 NAD(P) binding site [chemical binding]; other site 291112000539 HMMPfam hit to PF02812, Glu/Leu/Phe/Val dehydrogenase, dimeri, score 8.4e-86 291112000540 HMMPfam hit to PF00208, Glutamate/Leucine/Phenylalanine/Valin, score 1.1e-134 291112000541 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112000542 S-adenosylmethionine binding site [chemical binding]; other site 291112000543 HMMPfam hit to PF04445, Protein of unknown function (DUF548), score 5.6e-162 291112000544 oligopeptidase A; Provisional; Region: PRK10911 291112000545 Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456 291112000546 active site 291112000547 Zn binding site [ion binding]; other site 291112000548 HMMPfam hit to PF01432, Peptidase family M3, score 3e-214 291112000549 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112000550 1 probable transmembrane helix predicted for PAT2145 by TMHMM2.0 at aa 12-29 291112000551 Amidinotransferase; Region: Amidinotransf; cl12043 291112000552 HMMPfam hit to PF02274, Amidinotransferase, score 2.3e-05 291112000553 Fatty acid desaturase; Region: FA_desaturase; pfam00487 291112000554 The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615 291112000555 putative di-iron ligands [ion binding]; other site 291112000556 4 probable transmembrane helices predicted for PAT2148 by TMHMM2.0 at aa 12-31, 35-57, 132-154 and 195-217 291112000557 HMMPfam hit to PF00487, Fatty acid desaturase, score 1.8e-06 291112000558 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 291112000559 EamA-like transporter family; Region: EamA; pfam00892 291112000560 10 probable transmembrane helices predicted for PAT2150 by TMHMM2.0 at aa 7-29, 39-61, 77-96, 100-120, 127-149, 154-173, 180-202, 212-234, 241-263 and 267-286 291112000561 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.5e-10 291112000562 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.3e-12 291112000563 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 291112000564 Beta-lactamase; Region: Beta-lactamase; pfam00144 291112000565 HMMPfam hit to PF00144, Beta-lactamase, score 5.2e-59 291112000566 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 291112000567 Beta-lactamase; Region: Beta-lactamase; pfam00144 291112000568 HMMPfam hit to PF00144, Beta-lactamase, score 4.4e-61 291112000569 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 291112000570 Beta-lactamase; Region: Beta-lactamase; pfam00144 291112000571 HMMPfam hit to PF00144, Beta-lactamase, score 1.3e-65 291112000572 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 291112000573 Beta-lactamase; Region: Beta-lactamase; pfam00144 291112000574 HMMPfam hit to PF00144, Beta-lactamase, score 5.5e-60 291112000575 hypothetical protein; Provisional; Region: PRK01184 291112000576 Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286 291112000577 catalytic motif [active] 291112000578 Zn binding site [ion binding]; other site 291112000579 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 4.4e-23 291112000580 mannonate dehydratase; Provisional; Region: PRK03906 291112000581 mannonate dehydratase; Region: uxuA; TIGR00695 291112000582 HMMPfam hit to PF03786, D-mannonate dehydratase (UxuA), score 1.5e-244 291112000583 DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225 291112000584 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 291112000585 DNA-binding site [nucleotide binding]; DNA binding site 291112000586 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 291112000587 HMMPfam hit to PF07729, FCD domain, score 4.2e-36 291112000588 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 2.9e-25 291112000589 HMMSmart hit to SM00345, no description, score 4.7e-23 291112000590 TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638 291112000591 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112000592 membrane-bound complex binding site; other site 291112000593 HMMPfam hit to PF03480, Bacterial extracellular solute-binding prot, score 3.9e-101 291112000594 1 probable transmembrane helix predicted for PAT2158 by TMHMM2.0 at aa 7-29 291112000595 TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090 291112000596 4 probable transmembrane helices predicted for PAT2159 by TMHMM2.0 at aa 13-32, 47-65, 86-108 and 123-145 291112000597 HMMPfam hit to PF04290, Tripartite ATP-independent periplasmic trans, score 1.4e-34 291112000598 DctM-like transporters; Region: DctM; pfam06808 291112000599 TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593 291112000600 13 probable transmembrane helices predicted for PAT2160 by TMHMM2.0 at aa 5-27, 32-54, 59-81, 101-123, 144-166, 176-198, 219-241, 246-265, 278-300, 310-332, 339-358, 368-390 and 402-424 291112000601 HMMPfam hit to PF06808, DctM-like transporters, score 4.8e-148 291112000602 D-mannonate oxidoreductase; Provisional; Region: PRK15037 291112000603 Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232 291112000604 Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125 291112000605 HMMPfam hit to PF01232, Mannitol dehydrogenase Rossmann domain, score 1.5e-77 291112000606 HMMPfam hit to PF08125, Mannitol dehydrogenase C-terminal domai, score 2e-110 291112000607 Glucuronate isomerase; Region: UxaC; pfam02614 291112000608 Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904 291112000609 HMMPfam hit to PF02614, Glucuronate isomerase, score 0 291112000610 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 291112000611 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 291112000612 substrate binding site [chemical binding]; other site 291112000613 ATP binding site [chemical binding]; other site 291112000614 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 5.7e-66 291112000615 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718 291112000616 KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452 291112000617 active site 291112000618 intersubunit interface [polypeptide binding]; other site 291112000619 catalytic residue [active] 291112000620 HMMPfam hit to PF01081, KDPG and KHG aldolase, score 6.3e-103 291112000621 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872 291112000622 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112000623 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 7.8e-61 291112000624 glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266 291112000625 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 6.4e-69 291112000626 DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906 291112000627 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220 291112000628 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 291112000629 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 4.2e-76 291112000630 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 1.1e-28 291112000631 HMMSmart hit to SM00420, no description, score 1.5e-25 291112000632 HMMPfam hit to PF08279, HTH domain, score 0.00042 291112000633 rhomboid family protease GlpG; Region: rhombo_GlpG; TIGR04239 291112000634 Protein of unknown function (DUF3582); Region: DUF3582; pfam12122 291112000635 Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705 291112000636 HMMPfam hit to PF01694, Rhomboid family, score 2.8e-31 291112000637 6 probable transmembrane helices predicted for PAT2171 by TMHMM2.0 at aa 68-90, 113-135, 148-167, 171-188, 197-214 and 219-241 291112000638 GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444 291112000639 active site residue [active] 291112000640 HMMSmart hit to SM00450, no description, score 1.4e-19 291112000641 HMMPfam hit to PF00581, Rhodanese-like domain, score 5e-16 291112000642 Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190 291112000643 Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316 291112000644 Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694 291112000645 HMMPfam hit to PF01106, NifU-like domain, score 1.8e-07 291112000646 HMMPfam hit to PF01521, Iron-sulphur cluster biosynthesis, score 9.8e-32 291112000647 DNA utilization protein GntX; Provisional; Region: PRK11595 291112000648 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112000649 active site 291112000650 tyrosyl-tRNA synthetase; Provisional; Region: PRK13354 291112000651 catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805 291112000652 active site 291112000653 HIGH motif; other site 291112000654 dimer interface [polypeptide binding]; other site 291112000655 KMSKS motif; other site 291112000656 HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 2.6e-89 291112000657 HMMPfam hit to PF01479, S4 domain, score 0.017 291112000658 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 291112000659 B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293 291112000660 B12 binding site [chemical binding]; other site 291112000661 Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729 291112000662 HMMSmart hit to SM00729, no description, score 2e-21 291112000663 HMMPfam hit to PF04055, Radical SAM superfamily, score 3.1e-18 291112000664 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721 291112000665 HMMPfam hit to PF05721, Phytanoyl-CoA dioxygenase (PhyH), score 5e-17 291112000666 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721 291112000667 HMMPfam hit to PF05721, Phytanoyl-CoA dioxygenase (PhyH), score 4e-26 291112000668 putative transporter; Provisional; Region: PRK10054 291112000669 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112000670 putative substrate translocation pore; other site 291112000671 12 probable transmembrane helices predicted for PAT2182 by TMHMM2.0 at aa 19-41, 51-73, 82-101, 106-128, 141-163, 178-200, 221-243, 258-280, 287-309, 313-335, 356-375 and 379-398 291112000672 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4e-35 291112000673 carboxylesterase BioH; Provisional; Region: PRK10349 291112000674 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.1e-23 291112000675 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112000676 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112000677 non-specific DNA binding site [nucleotide binding]; other site 291112000678 salt bridge; other site 291112000679 sequence-specific DNA binding site [nucleotide binding]; other site 291112000680 HMMSmart hit to SM00530, no description, score 3.7e-13 291112000681 HMMPfam hit to PF01381, Helix-turn-helix, score 7.9e-15 291112000682 FeoC like transcriptional regulator; Region: FeoC; cl17677 291112000683 ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554 291112000684 Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879 291112000685 G1 box; other site 291112000686 GTP/Mg2+ binding site [chemical binding]; other site 291112000687 Switch I region; other site 291112000688 G2 box; other site 291112000689 G3 box; other site 291112000690 Switch II region; other site 291112000691 G4 box; other site 291112000692 G5 box; other site 291112000693 Nucleoside recognition; Region: Gate; pfam07670 291112000694 Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664 291112000695 Nucleoside recognition; Region: Gate; pfam07670 291112000696 10 probable transmembrane helices predicted for PAT2187 by TMHMM2.0 at aa 279-301, 316-338, 345-367, 387-409, 422-444, 454-476, 511-533, 663-685, 692-714 and 724-743 291112000697 HMMPfam hit to PF07670, Nucleoside recognition, score 2e-16 291112000698 HMMPfam hit to PF07664, Ferrous iron transport protein B C terminus, score 3.3e-24 291112000699 HMMPfam hit to PF07670, Nucleoside recognition, score 6.3e-16 291112000700 HMMPfam hit to PF02421, Ferrous iron transport protein B, score 2.6e-46 291112000701 HMMPfam hit to PF01926, GTPase of unknown function, score 1.5e-39 291112000702 ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555 291112000703 HMMPfam hit to PF04023, FeoA domain, score 4.2e-09 291112000704 Transcriptional accessory protein [Transcription]; Region: Tex; COG2183 291112000705 Tex-like protein N-terminal domain; Region: Tex_N; pfam09371 291112000706 Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732 291112000707 S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685 291112000708 RNA binding site [nucleotide binding]; other site 291112000709 HMMPfam hit to PF00575, S1 RNA binding domain, score 3.2e-28 291112000710 HMMSmart hit to SM00316, no description, score 4.6e-26 291112000711 HMMSmart hit to SM00732, no description, score 3.9e-37 291112000712 transcription elongation factor GreB; Reviewed; Region: greB; PRK01885 291112000713 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 291112000714 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 291112000715 HMMPfam hit to PF01272, Prokaryotic transcription elongation fact, score 1.1e-38 291112000716 HMMPfam hit to PF03449, Prokaryotic transcription elongation fact, score 4e-40 291112000717 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104 291112000718 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 291112000719 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112000720 catalytic residue [active] 291112000721 HMMPfam hit to PF00282, Pyridoxal-dependent decarboxylase con, score 0.00035 291112000722 HMMPfam hit to PF00266, Aminotransferase class-V, score 1.9e-100 291112000723 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.00018 291112000724 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112000725 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112000726 12 probable transmembrane helices predicted for PAT2195 by TMHMM2.0 at aa 7-29, 44-63, 70-88, 98-117, 130-152, 162-184, 204-226, 241-259, 271-293, 297-319, 332-354 and 359-381 291112000727 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.6e-23 291112000728 osmolarity response regulator; Provisional; Region: ompR; PRK09468 291112000729 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112000730 active site 291112000731 phosphorylation site [posttranslational modification] 291112000732 intermolecular recognition site; other site 291112000733 dimerization interface [polypeptide binding]; other site 291112000734 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112000735 DNA binding site [nucleotide binding] 291112000736 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.1e-39 291112000737 HMMSmart hit to SM00448, no description, score 2.5e-45 291112000738 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 4.6e-15 291112000739 osmolarity sensor protein; Provisional; Region: envZ; PRK09467 291112000740 HAMP domain; Region: HAMP; pfam00672 291112000741 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112000742 dimer interface [polypeptide binding]; other site 291112000743 phosphorylation site [posttranslational modification] 291112000744 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112000745 ATP binding site [chemical binding]; other site 291112000746 Mg2+ binding site [ion binding]; other site 291112000747 G-X-G motif; other site 291112000748 2 probable transmembrane helices predicted for PAT2197 by TMHMM2.0 at aa 15-37 and 160-179 291112000749 HMMPfam hit to PF00672, HAMP domain, score 0.0038 291112000750 HMMSmart hit to SM00388, no description, score 3.4e-11 291112000751 HMMSmart hit to SM00387, no description, score 3.8e-27 291112000752 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 8.2e-32 291112000753 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112000754 2 probable transmembrane helices predicted for PAT2198 by TMHMM2.0 at aa 29-51 and 64-86 291112000755 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 8.3e-31 291112000756 phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275 291112000757 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112000758 dimer interface [polypeptide binding]; other site 291112000759 conserved gate region; other site 291112000760 putative PBP binding loops; other site 291112000761 ABC-ATPase subunit interface; other site 291112000762 6 probable transmembrane helices predicted for PAT2199 by TMHMM2.0 at aa 27-49, 83-105, 117-139, 171-193, 232-254 and 287-309 291112000763 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 6.7e-14 291112000764 phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268 291112000765 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112000766 dimer interface [polypeptide binding]; other site 291112000767 conserved gate region; other site 291112000768 putative PBP binding loops; other site 291112000769 ABC-ATPase subunit interface; other site 291112000770 6 probable transmembrane helices predicted for PAT2200 by TMHMM2.0 at aa 28-50, 87-109, 122-144, 149-168, 200-222 and 267-289 291112000771 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.8e-38 291112000772 phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744 291112000773 ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260 291112000774 Walker A/P-loop; other site 291112000775 ATP binding site [chemical binding]; other site 291112000776 Q-loop/lid; other site 291112000777 ABC transporter signature motif; other site 291112000778 Walker B; other site 291112000779 D-loop; other site 291112000780 H-loop/switch region; other site 291112000781 HMMSmart hit to SM00382, no description, score 2.9e-10 291112000782 HMMPfam hit to PF00005, ABC transporter, score 2e-68 291112000783 transcriptional regulator PhoU; Provisional; Region: PRK11115 291112000784 PhoU domain; Region: PhoU; pfam01895 291112000785 PhoU domain; Region: PhoU; pfam01895 291112000786 HMMPfam hit to PF01895, PhoU family, score 1.9e-31 291112000787 HMMPfam hit to PF01895, PhoU family, score 8.4e-29 291112000788 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 291112000789 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112000790 substrate binding pocket [chemical binding]; other site 291112000791 membrane-bound complex binding site; other site 291112000792 hinge residues; other site 291112000793 1 probable transmembrane helix predicted for PAT2203 by TMHMM2.0 at aa 13-30 291112000794 HMMSmart hit to SM00062, no description, score 1.9e-68 291112000795 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 3.1e-71 291112000796 HMMSmart hit to SM00079, no description, score 0.0045 291112000797 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112000798 dimer interface [polypeptide binding]; other site 291112000799 conserved gate region; other site 291112000800 putative PBP binding loops; other site 291112000801 ABC-ATPase subunit interface; other site 291112000802 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-16 291112000803 3 probable transmembrane helices predicted for PAT2204 by TMHMM2.0 at aa 22-44, 65-87 and 107-129 291112000804 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 291112000805 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112000806 dimer interface [polypeptide binding]; other site 291112000807 conserved gate region; other site 291112000808 putative PBP binding loops; other site 291112000809 ABC-ATPase subunit interface; other site 291112000810 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.5e-20 291112000811 5 probable transmembrane helices predicted for PAT2205 by TMHMM2.0 at aa 27-49, 56-78, 93-115, 161-183 and 198-220 291112000812 Homeodomain-like domain; Region: HTH_23; cl17451 291112000813 Helix-turn-helix domain; Region: HTH_28; pfam13518 291112000814 putative transposase OrfB; Reviewed; Region: PHA02517 291112000815 HTH-like domain; Region: HTH_21; pfam13276 291112000816 Integrase core domain; Region: rve; pfam00665 291112000817 Integrase core domain; Region: rve_2; pfam13333 291112000818 HMMPfam hit to PF00665, Integrase core domain, score 2.2e-42 291112000819 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 291112000820 Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231 291112000821 10 probable transmembrane helices predicted for PAT2209 by TMHMM2.0 at aa 12-34, 57-74, 76-98, 108-125, 132-149, 164-186, 198-217, 243-262, 274-293 and 329-351 291112000822 Der GTPase activator; Provisional; Region: PRK05244 291112000823 HMMPfam hit to PF04220, Protein of unknown function, DUF414, score 6.3e-46 291112000824 coproporphyrinogen III oxidase; Provisional; Region: PRK09249 291112000825 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112000826 FeS/SAM binding site; other site 291112000827 HemN C-terminal domain; Region: HemN_C; pfam06969 291112000828 HMMSmart hit to SM00729, no description, score 7.6e-53 291112000829 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.2e-23 291112000830 HMMPfam hit to PF06969, HemN C-terminal region, score 1.4e-51 291112000831 nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923 291112000832 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112000833 active site 291112000834 phosphorylation site [posttranslational modification] 291112000835 intermolecular recognition site; other site 291112000836 dimerization interface [polypeptide binding]; other site 291112000837 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112000838 Walker A motif; other site 291112000839 ATP binding site [chemical binding]; other site 291112000840 Walker B motif; other site 291112000841 arginine finger; other site 291112000842 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 291112000843 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 2.3e-13 291112000844 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.1e-145 291112000845 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00055 291112000846 HMMSmart hit to SM00382, no description, score 3.8e-12 291112000847 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.2e-36 291112000848 HMMSmart hit to SM00448, no description, score 6.9e-35 291112000849 nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073 291112000850 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 291112000851 putative active site [active] 291112000852 heme pocket [chemical binding]; other site 291112000853 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112000854 dimer interface [polypeptide binding]; other site 291112000855 phosphorylation site [posttranslational modification] 291112000856 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112000857 ATP binding site [chemical binding]; other site 291112000858 Mg2+ binding site [ion binding]; other site 291112000859 G-X-G motif; other site 291112000860 HMMSmart hit to SM00387, no description, score 3.7e-30 291112000861 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.3e-28 291112000862 HMMSmart hit to SM00388, no description, score 1.6e-15 291112000863 HMMPfam hit to PF00989, PAS fold, score 0.0038 291112000864 HMMSmart hit to SM00091, no description, score 0.00059 291112000865 mGOT9n 291112000866 glutamine synthetase; Provisional; Region: glnA; PRK09469 291112000867 Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951 291112000868 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 291112000869 HMMPfam hit to PF00120, Glutamine synthetase, catalytic domain, score 6.9e-171 291112000870 HMMPfam hit to PF03951, Glutamine synthetase, beta-Grasp domain, score 2.6e-47 291112000871 Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217 291112000872 Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891 291112000873 G1 box; other site 291112000874 putative GEF interaction site [polypeptide binding]; other site 291112000875 GTP/Mg2+ binding site [chemical binding]; other site 291112000876 Switch I region; other site 291112000877 G2 box; other site 291112000878 G3 box; other site 291112000879 Switch II region; other site 291112000880 G4 box; other site 291112000881 G5 box; other site 291112000882 BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu. BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691 291112000883 BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants. BipA is a highly...; Region: BipA_TypA_C; cd03710 291112000884 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 7.3e-72 291112000885 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1e-14 291112000886 HMMPfam hit to PF00679, Elongation factor G C-terminus, score 1.4e-17 291112000887 Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495 291112000888 5 probable transmembrane helices predicted for PAT2216 by TMHMM2.0 at aa 13-35, 48-65, 72-94, 114-136 and 148-170 291112000889 Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966 291112000890 Carbon starvation protein CstA; Region: CstA; pfam02554 291112000891 C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722 291112000892 13 probable transmembrane helices predicted for PAT2217 by TMHMM2.0 at aa 4-22, 53-75, 79-101, 126-148, 163-182, 189-211, 231-249, 269-291, 315-337, 366-388, 392-411, 416-438 and 443-465 291112000893 HMMPfam hit to PF02554, Carbon starvation protein CstA, score 1.5e-79 291112000894 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509 291112000895 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112000896 motif II; other site 291112000897 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 3.6e-17 291112000898 D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563 291112000899 putative active site [active] 291112000900 dimerization interface [polypeptide binding]; other site 291112000901 putative tRNAtyr binding site [nucleotide binding]; other site 291112000902 HMMPfam hit to PF02580, D-Tyr-tRNA(Tyr) deacylase, score 8.4e-78 291112000903 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112000904 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 291112000905 Coenzyme A binding pocket [chemical binding]; other site 291112000906 Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500 291112000907 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.9e-16 291112000908 RelB antitoxin; Region: RelB; cl01171 291112000909 HMMPfam hit to PF04221, RelB antitoxin, score 0.00062 291112000910 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396 291112000911 HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 1.6e-07 291112000912 AsmA family; Region: AsmA; pfam05170 291112000913 HMMPfam hit to PF05170, AsmA family, score 7.9e-62 291112000914 1 probable transmembrane helix predicted for PAT2223 by TMHMM2.0 at aa 13-35 291112000915 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310 291112000916 4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241 291112000917 HMMPfam hit to PF03241, 4-hydroxyphenylacetate 3-hydroxylase family, score 5.4e-162 291112000918 Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233 291112000919 11 probable transmembrane helices predicted for PAT2225 by TMHMM2.0 at aa 41-63, 70-89, 124-146, 155-177, 192-211, 218-240, 260-282, 350-372, 377-399, 406-428 and 438-457 291112000920 HMMPfam hit to PF00860, Permease family, score 9.2e-150 291112000921 sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210 291112000922 HMMPfam hit to PF03616, Sodium/glutamate symporter, score 4.8e-235 291112000923 11 probable transmembrane helices predicted for PAT2226 by TMHMM2.0 at aa 4-21, 33-55, 70-87, 94-116, 162-184, 213-235, 245-267, 274-292, 302-324, 337-359 and 374-396 291112000924 Fic family protein [Function unknown]; Region: COG3177 291112000925 bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235 291112000926 HMMPfam hit to PF04221, RelB antitoxin, score 2.2e-11 291112000927 Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026 291112000928 HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 1.4e-12 291112000929 Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604 291112000930 HMMPfam hit to PF02604, Phd_YefM, score 6.1e-18 291112000931 ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917 291112000932 RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488 291112000933 generic binding surface II; other site 291112000934 ssDNA binding site; other site 291112000935 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112000936 ATP binding site [chemical binding]; other site 291112000937 putative Mg++ binding site [ion binding]; other site 291112000938 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112000939 nucleotide binding region [chemical binding]; other site 291112000940 ATP-binding site [chemical binding]; other site 291112000941 HMMSmart hit to SM00490, no description, score 3.6e-21 291112000942 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.4e-22 291112000943 HMMSmart hit to SM00487, no description, score 1.8e-31 291112000944 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1e-32 291112000945 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 3.1e-05 291112000946 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 8.9e-10 291112000947 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112000948 active site 291112000949 DNA binding site [nucleotide binding] 291112000950 Int/Topo IB signature motif; other site 291112000951 HMMPfam hit to PF00589, Phage integrase family, score 4.1e-41 291112000952 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112000953 HMMPfam hit to PF00419, Fimbrial protein, score 5.9e-05 291112000954 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 291112000955 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 291112000956 Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753 291112000957 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 8.6e-26 291112000958 HMMPfam hit to PF02753, Gram-negative pili assembly chaperone, score 9.1e-10 291112000959 Fimbrial protein; Region: Fimbrial; pfam00419 291112000960 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112000961 1 probable transmembrane helix predicted for PAT2236 by TMHMM2.0 at aa 26-48 291112000962 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112000963 HMMPfam hit to PF00419, Fimbrial protein, score 0.00063 291112000964 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 291112000965 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 291112000966 Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753 291112000967 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 9e-27 291112000968 HMMPfam hit to PF02753, Gram-negative pili assembly chaperone, score 5.1e-19 291112000969 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 291112000970 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 291112000971 Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753 291112000972 1 probable transmembrane helix predicted for PAT2239 by TMHMM2.0 at aa 12-30 291112000973 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 7.2e-22 291112000974 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 291112000975 PapC N-terminal domain; Region: PapC_N; pfam13954 291112000976 Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577 291112000977 PapC C-terminal domain; Region: PapC_C; pfam13953 291112000978 HMMPfam hit to PF00577, Fimbrial Usher protein, score 5.3e-303 291112000979 1 probable transmembrane helix predicted for PAT2241 by TMHMM2.0 at aa 42-64 291112000980 Protein of unknown function (DUF1401); Region: DUF1401; pfam07180 291112000981 2 probable transmembrane helices predicted for PAT2243 by TMHMM2.0 at aa 29-51 and 63-85 291112000982 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092 291112000983 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 291112000984 Zn2+ binding site [ion binding]; other site 291112000985 Mg2+ binding site [ion binding]; other site 291112000986 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 291112000987 synthetase active site [active] 291112000988 NTP binding site [chemical binding]; other site 291112000989 metal binding site [ion binding]; metal-binding site 291112000990 TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668 291112000991 ACT domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876 291112000992 HMMPfam hit to PF02824, TGS domain, score 3.3e-27 291112000993 HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 1e-47 291112000994 HMMSmart hit to SM00471, no description, score 8.3e-12 291112000995 HMMPfam hit to PF01966, HD domain, score 5.9e-16 291112000996 DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690 291112000997 HMMPfam hit to PF01192, RNA polymerase Rpb6, score 7e-22 291112000998 Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194 291112000999 Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071 291112001000 catalytic site [active] 291112001001 G-X2-G-X-G-K; other site 291112001002 HMMSmart hit to SM00072, no description, score 1.6e-76 291112001003 HMMPfam hit to PF00625, Guanylate kinase, score 1.2e-53 291112001004 Predicted nuclease of the RNAse H fold, HicB family [General function prediction only]; Region: COG1598 291112001005 HMMPfam hit to PF03681, Uncharacterised protein family (UPF0150), score 1.2e-11 291112001006 1 probable transmembrane helix predicted for PAT2248 by TMHMM2.0 at aa 21-43 291112001007 1 probable transmembrane helix predicted for PAT2249 by TMHMM2.0 at aa 21-43 291112001008 1 probable transmembrane helix predicted for PAT2250 by TMHMM2.0 at aa 42-64 291112001009 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112001010 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112001011 non-specific DNA binding site [nucleotide binding]; other site 291112001012 salt bridge; other site 291112001013 sequence-specific DNA binding site [nucleotide binding]; other site 291112001014 HMMSmart hit to SM00530, no description, score 3.2e-10 291112001015 HMMPfam hit to PF01381, Helix-turn-helix, score 8.2e-11 291112001016 Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973 291112001017 CcdB protein; Region: CcdB; cl03380 291112001018 Post-segregation antitoxin CcdA; Region: CcdA; cl02188 291112001019 NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097 291112001020 NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295 291112001021 nucleotide binding pocket [chemical binding]; other site 291112001022 K-X-D-G motif; other site 291112001023 catalytic site [active] 291112001024 NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120 291112001025 HMMPfam hit to PF01653, NAD-dependent DNA ligase adenylation, score 3.4e-19 291112001026 HMMSmart hit to SM00532, no description, score 2.6e-41 291112001027 HMMPfam hit to PF03120, NAD-dependent DNA ligase OB-fold doma, score 1.5e-17 291112001028 Predicted membrane protein [Function unknown]; Region: COG2860 291112001029 UPF0126 domain; Region: UPF0126; pfam03458 291112001030 UPF0126 domain; Region: UPF0126; pfam03458 291112001031 7 probable transmembrane helices predicted for PAT2257 by TMHMM2.0 at aa 5-22, 29-51, 64-81, 88-107, 111-133, 140-162 and 172-189 291112001032 HMMPfam hit to PF03458, UPF0126 domain, score 3.8e-34 291112001033 HMMPfam hit to PF03458, UPF0126 domain, score 2.2e-37 291112001034 Protein of unknown function (DUF3748); Region: DUF3748; pfam12566 291112001035 hypothetical protein; Provisional; Region: PRK11616 291112001036 HMMPfam hit to PF07119, Protein of unknown function (DUF1375), score 3.7e-34 291112001037 1 probable transmembrane helix predicted for PAT2259 by TMHMM2.0 at aa 7-29 291112001038 valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440 291112001039 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112001040 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112001041 homodimer interface [polypeptide binding]; other site 291112001042 catalytic residue [active] 291112001043 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.5e-07 291112001044 Methyladenine glycosylase; Region: Adenine_glyco; pfam03352 291112001045 HMMPfam hit to PF03352, Methyladenine glycosylase, score 3.3e-109 291112001046 Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733 291112001047 dimer interface [polypeptide binding]; other site 291112001048 motif 1; other site 291112001049 active site 291112001050 motif 2; other site 291112001051 motif 3; other site 291112001052 HMMPfam hit to PF02091, Glycyl-tRNA synthetase alpha subunit, score 4.3e-244 291112001053 glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233 291112001054 Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020 291112001055 HMMPfam hit to PF02092, Glycyl-tRNA synthetase beta subunit, score 0 291112001056 HMMPfam hit to PF05746, DALR anticodon binding domain, score 1.4e-05 291112001057 Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973 291112001058 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112001059 non-specific DNA binding site [nucleotide binding]; other site 291112001060 salt bridge; other site 291112001061 sequence-specific DNA binding site [nucleotide binding]; other site 291112001062 HMMSmart hit to SM00530, no description, score 3.1e-09 291112001063 HMMPfam hit to PF01381, Helix-turn-helix, score 3.7e-10 291112001064 1 probable transmembrane helix predicted for PAT2265 by TMHMM2.0 at aa 12-34 291112001065 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 291112001066 The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493 291112001067 peptide binding site [polypeptide binding]; other site 291112001068 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 8.1e-95 291112001069 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 291112001070 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112001071 dimer interface [polypeptide binding]; other site 291112001072 conserved gate region; other site 291112001073 putative PBP binding loops; other site 291112001074 ABC-ATPase subunit interface; other site 291112001075 6 probable transmembrane helices predicted for PAT2267 by TMHMM2.0 at aa 9-31, 99-121, 134-156, 202-221, 259-281 and 309-331 291112001076 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 9.5e-58 291112001077 dipeptide transporter; Provisional; Region: PRK10913 291112001078 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112001079 putative PBP binding loops; other site 291112001080 dimer interface [polypeptide binding]; other site 291112001081 ABC-ATPase subunit interface; other site 291112001082 5 probable transmembrane helices predicted for PAT2268 by TMHMM2.0 at aa 31-53, 103-125, 140-162, 210-232 and 265-287 291112001083 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.7e-46 291112001084 dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022 291112001085 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 291112001086 Walker A/P-loop; other site 291112001087 ATP binding site [chemical binding]; other site 291112001088 Q-loop/lid; other site 291112001089 ABC transporter signature motif; other site 291112001090 Walker B; other site 291112001091 D-loop; other site 291112001092 H-loop/switch region; other site 291112001093 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 291112001094 HMMSmart hit to SM00382, no description, score 5.9e-13 291112001095 HMMPfam hit to PF00005, ABC transporter, score 5.2e-60 291112001096 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 6.5e-25 291112001097 dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308 291112001098 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 291112001099 Walker A/P-loop; other site 291112001100 ATP binding site [chemical binding]; other site 291112001101 Q-loop/lid; other site 291112001102 ABC transporter signature motif; other site 291112001103 Walker B; other site 291112001104 D-loop; other site 291112001105 H-loop/switch region; other site 291112001106 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 291112001107 HMMSmart hit to SM00382, no description, score 3.3e-12 291112001108 HMMPfam hit to PF00005, ABC transporter, score 1.4e-62 291112001109 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 8.7e-31 291112001110 biofilm formation regulator HmsP; Provisional; Region: PRK11829 291112001111 2 probable transmembrane helices predicted for PAT2271 by TMHMM2.0 at aa 15-37 and 161-183 291112001112 Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612 291112001113 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 291112001114 HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 0.049 291112001115 HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 2.4e-06 291112001116 Membrane protein of unknown function (DUF340); Region: DUF340; pfam03956 291112001117 8 probable transmembrane helices predicted for PAT2274 by TMHMM2.0 at aa 4-21, 33-50, 65-84, 104-121, 136-155, 162-184, 216-238 and 273-295 291112001118 HMMPfam hit to PF03956, Membrane protein of unknown function (DUF340, score 1.5e-34 291112001119 Biofilm formation and stress response factor; Region: BsmA; pfam10014 291112001120 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491 291112001121 active site 1 [active] 291112001122 dimer interface [polypeptide binding]; other site 291112001123 hexamer interface [polypeptide binding]; other site 291112001124 active site 2 [active] 291112001125 HMMPfam hit to PF01361, Tautomerase enzyme, score 1.9e-23 291112001126 Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918 291112001127 Region 10 291112001128 HMMPfam hit to PF03631, Ribonuclease BN-like family, score 2.6e-26 291112001129 6 probable transmembrane helices predicted for PAT2277 by TMHMM2.0 at aa 89-111, 149-168, 200-222, 242-264, 276-298 and 313-335 291112001130 1 probable transmembrane helix predicted for PAT2278 by TMHMM2.0 at aa 7-29 291112001131 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112001132 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112001133 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112001134 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112001135 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112001136 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112001137 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112001138 HMMPfam hit to PF05594, Haemagluttinin repeat, score 2.7e-05 291112001139 HMMPfam hit to PF05860, haemagglutination activity domain, score 9.3e-43 291112001140 Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831 291112001141 POTRA domain, ShlB-type; Region: POTRA_2; pfam08479 291112001142 Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865 291112001143 HMMPfam hit to PF03865, Haemolysin secretion/activation protein ShlB, score 1.8e-228 291112001144 HMMPfam hit to PF08479, POTRA domain, ShlB-type, score 1.2e-24 291112001145 Inclusion body protein; Region: PixA; pfam12306 291112001146 Inclusion body protein; Region: PixA; pfam12306 291112001147 Inclusion body protein; Region: PixA; pfam12306 291112001148 Inclusion body protein; Region: PixA; pfam12306 291112001149 Inclusion body protein; Region: PixA; pfam12306 291112001150 Autoinducer binding domain; Region: Autoind_bind; pfam03472 291112001151 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112001152 DNA binding residues [nucleotide binding] 291112001153 dimerization interface [polypeptide binding]; other site 291112001154 HMMPfam hit to PF03472, Autoinducer binding domain, score 2.8e-05 291112001155 HMMSmart hit to SM00421, no description, score 4.8e-16 291112001156 2 probable transmembrane helices predicted for PAT2288 by TMHMM2.0 at aa 13-35 and 39-56 291112001157 Inclusion body protein; Region: PixA; pfam12306 291112001158 Autoinducer binding domain; Region: Autoind_bind; pfam03472 291112001159 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112001160 DNA binding residues [nucleotide binding] 291112001161 dimerization interface [polypeptide binding]; other site 291112001162 HMMPfam hit to PF03472, Autoinducer binding domain, score 5e-06 291112001163 HMMSmart hit to SM00421, no description, score 6.6e-18 291112001164 Fijivirus 64 kDa capsid protein; Region: Fiji_64_capsid; pfam05880 291112001165 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112001166 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112001167 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112001168 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112001169 PAAR motif; Region: PAAR_motif; pfam05488 291112001170 HMMPfam hit to PF05488, PAAR motif, score 1.8e-09 291112001171 HMMPfam hit to PF05488, PAAR motif, score 0.00073 291112001172 1 probable transmembrane helix predicted for PAT2299 by TMHMM2.0 at aa 7-24 291112001173 para-aminobenzoate synthase component II; Provisional; Region: PRK08857 291112001174 1 probable transmembrane helix predicted for PAT2303 by TMHMM2.0 at aa 25-44 291112001175 1 probable transmembrane helix predicted for PAT2305 by TMHMM2.0 at aa 4-21 291112001176 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112001177 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112001178 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112001179 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112001180 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3515 291112001181 ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812 291112001182 ImpA domain protein; Region: DUF3702; pfam12486 291112001183 1 probable transmembrane helix predicted for PAT2309 by TMHMM2.0 at aa 232-254 291112001184 HMMPfam hit to PF06812, ImpA-related N-terminal, score 4.2e-27 291112001185 Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and vesicular transport]; Region: IcmF; COG3523 291112001186 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 291112001187 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 291112001188 HMMPfam hit to PF06744, Protein of unknown function (DUF1215), score 1.9e-60 291112001189 HMMPfam hit to PF06761, ImcF-related, score 7.6e-126 291112001190 3 probable transmembrane helices predicted for PAT2310 by TMHMM2.0 at aa 22-44, 59-78 and 457-479 291112001191 ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812 291112001192 type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362 291112001193 HMMPfam hit to PF06812, ImpA-related N-terminal, score 6.4e-20 291112001194 Protein of unknown function (DUF3121); Region: DUF3121; pfam11319 291112001195 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 291112001196 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis family, score 0.00023 291112001197 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112001198 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 291112001199 Walker A motif; other site 291112001200 ATP binding site [chemical binding]; other site 291112001201 Walker B motif; other site 291112001202 arginine finger; other site 291112001203 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112001204 Walker A motif; other site 291112001205 ATP binding site [chemical binding]; other site 291112001206 Walker B motif; other site 291112001207 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 291112001208 HMMSmart hit to SM00382, no description, score 1.4e-06 291112001209 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 1.1e-07 291112001210 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 8.8e-85 291112001211 HMMSmart hit to SM00382, no description, score 1.3e-08 291112001212 HMMPfam hit to PF02861, Clp amino terminal domain, score 0.033 291112001213 Type VI protein secretion system component VasF [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3455 291112001214 1 probable transmembrane helix predicted for PAT2315 by TMHMM2.0 at aa 216-238 291112001215 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3522 291112001216 Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936 291112001217 HMMPfam hit to PF05936, Bacterial protein of unknown function (DUF87, score 9.4e-214 291112001218 type VI secretion lipoprotein, VC_A0113 family; Region: VI_chp_3; TIGR03352 291112001219 1 probable transmembrane helix predicted for PAT2317 by TMHMM2.0 at aa 9-31 291112001220 type VI secretion system FHA domain protein; Region: VI_FHA; TIGR03354 291112001221 HMMPfam hit to PF00498, FHA domain, score 0.00012 291112001222 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3520 291112001223 HMMPfam hit to PF06996, Protein of unknown function (DUF1305), score 4.2e-122 291112001224 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 291112001225 type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359 291112001226 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 2.3e-212 291112001227 type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357 291112001228 HMMPfam hit to PF07025, Protein of unknown function (DUF1316), score 1.4e-43 291112001229 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3517 291112001230 Protein of unknown function (DUF877); Region: DUF877; pfam05943 291112001231 HMMPfam hit to PF05943, Protein of unknown function (DUF877), score 0 291112001232 Protein of unknown function (DUF770); Region: DUF770; pfam05591 291112001233 HMMPfam hit to PF05591, Protein of unknown function (DUF770), score 2.6e-80 291112001234 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112001235 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 7.7e-86 291112001236 Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961 291112001237 HMMPfam hit to PF04378, Protein of unknown function (DUF519), score 1.2e-153 291112001238 glutathione reductase; Validated; Region: PRK06116 291112001239 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 291112001240 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 291112001241 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 291112001242 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 3.4e-72 291112001243 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 2.8e-27 291112001244 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 1.2e-52 291112001245 hypothetical protein; Provisional; Region: PRK09956 291112001246 Putative transposase, YhgA-like; Region: Transposase_31; pfam04754 291112001247 HMMPfam hit to PF04754, Putative transposase, YhgA-like, score 5.1e-188 291112001248 conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784 291112001249 putative deaminase; Validated; Region: PRK06846 291112001250 Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293 291112001251 active site 291112001252 HMMPfam hit to PF07969, Amidohydrolase family, score 1.4e-08 291112001253 Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116 291112001254 Walker A motif; other site 291112001255 HMMPfam hit to PF03205, Molybdopterin guanine dinucleotide synthesis, score 3.6e-51 291112001256 molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317 291112001257 MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503 291112001258 GTP binding site; other site 291112001259 serine/threonine protein kinase; Provisional; Region: PRK11768 291112001260 Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334 291112001261 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 4.8e-40 291112001262 DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019 291112001263 DSBA-like thioredoxin domain; Region: DSBA; pfam01323 291112001264 catalytic residues [active] 291112001265 hinge region; other site 291112001266 alpha helical domain; other site 291112001267 HMMPfam hit to PF01323, DSBA-like thioredoxin domain, score 4.3e-47 291112001268 DNA polymerase I; Provisional; Region: PRK05755 291112001269 PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859 291112001270 active site 291112001271 metal binding site 1 [ion binding]; metal-binding site 291112001272 putative 5' ssDNA interaction site; other site 291112001273 metal binding site 3; metal-binding site 291112001274 metal binding site 2 [ion binding]; metal-binding site 291112001275 H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898 291112001276 putative DNA binding site [nucleotide binding]; other site 291112001277 putative metal binding site [ion binding]; other site 291112001278 DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139 291112001279 active site 291112001280 catalytic site [active] 291112001281 substrate binding site [chemical binding]; other site 291112001282 Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637 291112001283 active site 291112001284 DNA binding site [nucleotide binding] 291112001285 catalytic site [active] 291112001286 HMMSmart hit to SM00475, no description, score 3.1e-139 291112001287 HMMPfam hit to PF02739, 5'-3' exonuclease, N-terminal resolvase-, score 1.8e-96 291112001288 HMMPfam hit to PF01367, 5'-3' exonuclease, C-terminal SAM fold, score 1.9e-51 291112001289 HMMSmart hit to SM00279, no description, score 6.1e-14 291112001290 HMMSmart hit to SM00474, no description, score 1.1e-46 291112001291 HMMPfam hit to PF00476, DNA polymerase family A, score 1.3e-216 291112001292 HMMSmart hit to SM00482, no description, score 1.3e-124 291112001293 Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184 291112001294 YihA (EngB) GTPase family; Region: YihA_EngB; cd01876 291112001295 G1 box; other site 291112001296 GTP/Mg2+ binding site [chemical binding]; other site 291112001297 Switch I region; other site 291112001298 G2 box; other site 291112001299 G3 box; other site 291112001300 Switch II region; other site 291112001301 G4 box; other site 291112001302 G5 box; other site 291112001303 HMMPfam hit to PF01926, GTPase of unknown function, score 4.9e-30 291112001304 peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903 291112001305 cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197 291112001306 active site 291112001307 HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 3.2e-64 291112001308 Fels-1 Prophage Protein-like; Region: Fels1; pfam05666 291112001309 1 probable transmembrane helix predicted for PAT2338 by TMHMM2.0 at aa 5-27 291112001310 para-aminobenzoate synthase component II; Provisional; Region: PRK08857 291112001311 Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743 291112001312 glutamine binding [chemical binding]; other site 291112001313 catalytic triad [active] 291112001314 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.6e-85 291112001315 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093 291112001316 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 291112001317 inhibitor-cofactor binding pocket; inhibition site 291112001318 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112001319 catalytic residue [active] 291112001320 HMMPfam hit to PF00202, Aminotransferase class-III, score 2e-166 291112001321 DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753 291112001322 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 291112001323 ligand binding site [chemical binding]; other site 291112001324 flexible hinge region; other site 291112001325 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 291112001326 putative switch regulator; other site 291112001327 non-specific DNA interactions [nucleotide binding]; other site 291112001328 DNA binding site [nucleotide binding] 291112001329 sequence specific DNA binding site [nucleotide binding]; other site 291112001330 putative cAMP binding site [chemical binding]; other site 291112001331 HMMSmart hit to SM00419, no description, score 4.5e-17 291112001332 HMMPfam hit to PF00325, Bacterial regulatory proteins, crp famil, score 1.4e-15 291112001333 HMMSmart hit to SM00100, no description, score 1e-26 291112001334 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 7.4e-28 291112001335 hypothetical protein; Provisional; Region: PRK10738 291112001336 HMMPfam hit to PF02566, OsmC-like protein, score 5.2e-27 291112001337 phosphoribulokinase; Provisional; Region: PRK15453 291112001338 HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 2.6e-112 291112001339 hypothetical protein; Provisional; Region: PRK04966 291112001340 HMMPfam hit to PF06794, Uncharacterised protein family (UPF0270), score 9.2e-45 291112001341 putative hydrolase; Provisional; Region: PRK10985 291112001342 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.6e-20 291112001343 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 291112001344 5 probable transmembrane helices predicted for PAT2346 by TMHMM2.0 at aa 5-27, 40-62, 66-88, 142-164 and 179-201 291112001345 HMMPfam hit to PF01810, LysE type translocator, score 0.00091 291112001346 similar to INSD:AE015451; similar to INSD:BX936398; similar to INSD:CP000270; similar to INSD:D85613 291112001347 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 291112001348 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 291112001349 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 1.3e-25 291112001350 PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586 291112001351 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 291112001352 active site turn [active] 291112001353 phosphorylation site [posttranslational modification] 291112001354 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 291112001355 10 probable transmembrane helices predicted for PAT2350 by TMHMM2.0 at aa 127-149, 164-186, 193-212, 227-249, 270-292, 307-329, 341-363, 378-400, 407-429 and 449-471 291112001356 HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 8.6e-41 291112001357 HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 2.3e-10 291112001358 N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441 291112001359 N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007 291112001360 putative active site [active] 291112001361 HMMPfam hit to PF01380, SIS domain, score 0.032 291112001362 Predicted nuclease of restriction endonuclease-like fold [General function prediction only]; Region: COG4804 291112001363 HMMPfam hit to PF06250, Protein of unknown function (DUF1016), score 3e-75 291112001364 1 probable transmembrane helix predicted for PAT2353 by TMHMM2.0 at aa 19-38 291112001365 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112001366 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 1.1e-67 291112001367 2 probable transmembrane helices predicted for PAT2355 by TMHMM2.0 at aa 138-160 and 170-192 291112001368 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112001369 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 4.4e-42 291112001370 3 probable transmembrane helices predicted for PAT2356 by TMHMM2.0 at aa 7-29, 44-66 and 79-101 291112001371 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112001372 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 9.1e-45 291112001373 3 probable transmembrane helices predicted for PAT2357 by TMHMM2.0 at aa 7-29, 44-66 and 79-101 291112001374 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112001375 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 1.3e-46 291112001376 3 probable transmembrane helices predicted for PAT2358 by TMHMM2.0 at aa 21-40, 60-82 and 94-116 291112001377 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112001378 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 7.4e-47 291112001379 3 probable transmembrane helices predicted for PAT2359 by TMHMM2.0 at aa 7-28, 48-70 and 83-102 291112001380 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112001381 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 1.9e-40 291112001382 3 probable transmembrane helices predicted for PAT2360 by TMHMM2.0 at aa 21-40, 60-82 and 94-116 291112001383 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112001384 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112001385 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 1.4e-19 291112001386 putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636 291112001387 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112001388 Walker A/P-loop; other site 291112001389 ATP binding site [chemical binding]; other site 291112001390 Q-loop/lid; other site 291112001391 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112001392 ABC transporter; Region: ABC_tran_2; pfam12848 291112001393 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112001394 HMMSmart hit to SM00382, no description, score 4.6e-15 291112001395 HMMPfam hit to PF00005, ABC transporter, score 1.4e-44 291112001396 HMMSmart hit to SM00382, no description, score 1.8e-13 291112001397 HMMPfam hit to PF00005, ABC transporter, score 6.9e-46 291112001398 glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930 291112001399 HMMPfam hit to PF02525, Flavodoxin-like fold, score 3.9e-68 291112001400 glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659 291112001401 transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932 291112001402 TrkA-N domain; Region: TrkA_N; pfam02254 291112001403 12 probable transmembrane helices predicted for PAT2364 by TMHMM2.0 at aa 5-24, 29-51, 56-73, 86-108, 112-134, 147-169, 179-201, 222-244, 268-290, 295-317, 327-349 and 356-375 291112001404 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 4.4e-76 291112001405 HMMPfam hit to PF02254, TrkA-N domain, score 2.3e-27 291112001406 Probable metal-binding protein (DUF2387); Region: DUF2387; pfam09526 291112001407 FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737 291112001408 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 291112001409 HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 0.00023 291112001410 Protein of unknown function (DUF2645); Region: DUF2645; pfam10840 291112001411 3 probable transmembrane helices predicted for PAT2368 by TMHMM2.0 at aa 7-26, 55-72 and 79-98 291112001412 FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902 291112001413 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346 291112001414 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 291112001415 HMMPfam hit to PF01346, Domain amino terminal to FKBP-type peptidyl-, score 1.4e-42 291112001416 HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 1.9e-45 291112001417 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964 291112001418 YheO-like PAS domain; Region: PAS_6; pfam08348 291112001419 HTH domain; Region: HTH_22; pfam13309 291112001420 HMMPfam hit to PF08348, YheO-like protein, score 2.6e-56 291112001421 sulfur transfer complex subunit TusD; Validated; Region: PRK00207 291112001422 HMMPfam hit to PF02635, DsrE/DsrF-like family, score 1.6e-51 291112001423 sulfur relay protein TusC; Validated; Region: PRK00211 291112001424 HMMPfam hit to PF02635, DsrE/DsrF-like family, score 8.6e-36 291112001425 sulfur transfer complex subunit TusB; Provisional; Region: PRK13510 291112001426 HMMPfam hit to PF04077, DsrH like protein, score 7.3e-25 291112001427 S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368 291112001428 S17 interaction site [polypeptide binding]; other site 291112001429 S8 interaction site; other site 291112001430 16S rRNA interaction site [nucleotide binding]; other site 291112001431 streptomycin interaction site [chemical binding]; other site 291112001432 23S rRNA interaction site [nucleotide binding]; other site 291112001433 aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site 291112001434 HMMPfam hit to PF00164, Ribosomal protein S12, score 2.5e-74 291112001435 30S ribosomal protein S7; Validated; Region: PRK05302 291112001436 HMMPfam hit to PF00177, Ribosomal protein S7p/S5e, score 7.8e-87 291112001437 elongation factor G; Reviewed; Region: PRK00007 291112001438 Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886 291112001439 G1 box; other site 291112001440 putative GEF interaction site [polypeptide binding]; other site 291112001441 GTP/Mg2+ binding site [chemical binding]; other site 291112001442 Switch I region; other site 291112001443 G2 box; other site 291112001444 G3 box; other site 291112001445 Switch II region; other site 291112001446 G4 box; other site 291112001447 G5 box; other site 291112001448 EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088 291112001449 EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434 291112001450 EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G. Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713 291112001451 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.2e-110 291112001452 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.6e-21 291112001453 HMMPfam hit to PF03764, Elongation factor G, domain IV, score 7.6e-72 291112001454 HMMPfam hit to PF00679, Elongation factor G C-terminus, score 5.4e-51 291112001455 elongation factor Tu; Reviewed; Region: PRK00049 291112001456 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 291112001457 G1 box; other site 291112001458 GEF interaction site [polypeptide binding]; other site 291112001459 GTP/Mg2+ binding site [chemical binding]; other site 291112001460 Switch I region; other site 291112001461 G2 box; other site 291112001462 G3 box; other site 291112001463 Switch II region; other site 291112001464 G4 box; other site 291112001465 G5 box; other site 291112001466 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 291112001467 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 291112001468 Antibiotic Binding Site [chemical binding]; other site 291112001469 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.1e-99 291112001470 HMMPfam hit to PF03144, Elongation factor Tu domain, score 2.9e-25 291112001471 HMMPfam hit to PF03143, Elongation factor Tu C-terminal domain, score 1.9e-60 291112001472 preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740 291112001473 3 probable transmembrane helices predicted for PAT2380 by TMHMM2.0 at aa 19-36, 41-63 and 89-111 291112001474 HMMPfam hit to PF00584, SecE/Sec61-gamma subunits of protein translo, score 3e-23 291112001475 transcription antitermination protein NusG; Validated; Region: nusG; PRK05609 291112001476 Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891 291112001477 putative homodimer interface [polypeptide binding]; other site 291112001478 NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091 291112001479 heterodimer interface [polypeptide binding]; other site 291112001480 homodimer interface [polypeptide binding]; other site 291112001481 HMMSmart hit to SM00738, no description, score 1.3e-48 291112001482 HMMPfam hit to PF02357, Transcription termination factor nusG, score 1.8e-55 291112001483 HMMSmart hit to SM00739, no description, score 1e-06 291112001484 HMMPfam hit to PF00467, KOW motif, score 1.6e-11 291112001485 50S ribosomal protein L11; Validated; Region: rplK; PRK00140 291112001486 Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349 291112001487 23S rRNA interface [nucleotide binding]; other site 291112001488 L7/L12 interface [polypeptide binding]; other site 291112001489 putative thiostrepton binding site; other site 291112001490 L25 interface [polypeptide binding]; other site 291112001491 HMMPfam hit to PF03946, Ribosomal protein L11, N-terminal dom, score 1.8e-38 291112001492 HMMSmart hit to SM00649, no description, score 6.5e-84 291112001493 HMMPfam hit to PF00298, Ribosomal protein L11, RNA binding do, score 4.2e-37 291112001494 Ribosomal protein L1. The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA. In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403 291112001495 mRNA/rRNA interface [nucleotide binding]; other site 291112001496 HMMPfam hit to PF00687, Ribosomal protein L1p/L10e family, score 7.1e-137 291112001497 Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797 291112001498 23S rRNA interface [nucleotide binding]; other site 291112001499 Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site 291112001500 HMMPfam hit to PF00466, Ribosomal protein L10, score 1.2e-36 291112001501 Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387 291112001502 core dimer interface [polypeptide binding]; other site 291112001503 peripheral dimer interface [polypeptide binding]; other site 291112001504 L10 interface [polypeptide binding]; other site 291112001505 L11 interface [polypeptide binding]; other site 291112001506 putative EF-Tu interaction site [polypeptide binding]; other site 291112001507 putative EF-G interaction site [polypeptide binding]; other site 291112001508 HMMPfam hit to PF00542, Ribosomal protein L7/L12 C-terminal dom, score 1.7e-37 291112001509 DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405 291112001510 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585 291112001511 RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561 291112001512 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653 291112001513 RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562 291112001514 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653 291112001515 RPB3 interaction site [polypeptide binding]; other site 291112001516 RPB1 interaction site [polypeptide binding]; other site 291112001517 RPB11 interaction site [polypeptide binding]; other site 291112001518 RPB10 interaction site [polypeptide binding]; other site 291112001519 HMMPfam hit to PF04563, RNA polymerase beta subunit, score 6.8e-38 291112001520 HMMPfam hit to PF04561, RNA polymerase Rpb2, domain, score 1.7e-06 291112001521 HMMPfam hit to PF04565, RNA polymerase Rpb2, domain, score 1.8e-43 291112001522 HMMPfam hit to PF00562, RNA polymerase Rpb2, domain, score 5.2e-185 291112001523 HMMPfam hit to PF04560, RNA polymerase Rpb2, domain, score 4.1e-52 291112001524 RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997 291112001525 DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086 291112001526 RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663 291112001527 RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983 291112001528 RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000 291112001529 RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998 291112001530 Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429 291112001531 Rpb1 - Rpb6 interaction site [polypeptide binding]; other site 291112001532 Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429 291112001533 Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655 291112001534 DNA binding site [nucleotide binding] 291112001535 Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site 291112001536 HMMPfam hit to PF04997, RNA polymerase Rpb1, domain, score 1.6e-158 291112001537 HMMSmart hit to SM00663, no description, score 2.7e-184 291112001538 HMMPfam hit to PF00623, RNA polymerase Rpb1, domain, score 2e-83 291112001539 HMMPfam hit to PF04983, RNA polymerase Rpb1, domain, score 6.9e-49 291112001540 HMMPfam hit to PF05000, RNA polymerase Rpb1, domain, score 1.7e-29 291112001541 HMMPfam hit to PF04998, RNA polymerase Rpb1, domain, score 1.8e-109 291112001542 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112001543 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112001544 non-specific DNA binding site [nucleotide binding]; other site 291112001545 salt bridge; other site 291112001546 sequence-specific DNA binding site [nucleotide binding]; other site 291112001547 HMMSmart hit to SM00530, no description, score 3.8e-12 291112001548 HMMPfam hit to PF01381, Helix-turn-helix, score 1.5e-10 291112001549 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 291112001550 non-specific DNA binding site [nucleotide binding]; other site 291112001551 salt bridge; other site 291112001552 sequence-specific DNA binding site [nucleotide binding]; other site 291112001553 Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877 291112001554 HMMPfam hit to PF04014, SpoVT / AbrB like domain, score 5.1e-08 291112001555 PemK-like protein; Region: PemK; cl00995 291112001556 HMMPfam hit to PF02452, PemK-like protein, score 4.8e-14 291112001557 Protein similar to CwfJ C-terminus 1; Region: CwfJ_C_1; pfam04677 291112001558 Protein similar to CwfJ C-terminus 2; Region: CwfJ_C_2; pfam04676 291112001559 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 291112001560 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 291112001561 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112001562 catalytic residue [active] 291112001563 HMMPfam hit to PF00266, Aminotransferase class-V, score 4.2e-41 291112001564 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 291112001565 Cytidylyltransferase; Region: CTP_transf_2; pfam01467 291112001566 active site 291112001567 nucleotide binding site [chemical binding]; other site 291112001568 HIGH motif; other site 291112001569 KMSKS motif; other site 291112001570 GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585 291112001571 HMMPfam hit to PF02585, GlcNAc-PI de-N-acetylase, score 5.7e-23 291112001572 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 291112001573 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922 291112001574 HMMPfam hit to PF00534, Glycosyl transferases group, score 2.4e-27 291112001575 maltose regulon periplasmic protein; Provisional; Region: PRK10564 291112001576 HMMPfam hit to PF07148, Maltose operon periplasmic protein precursor, score 1.6e-115 291112001577 1 probable transmembrane helix predicted for PAT2400 by TMHMM2.0 at aa 5-27 291112001578 The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346 291112001579 trimer interface; other site 291112001580 sugar binding site [chemical binding]; other site 291112001581 HMMPfam hit to PF02264, LamB porin, score 4.6e-212 291112001582 maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000 291112001583 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 291112001584 Walker A/P-loop; other site 291112001585 ATP binding site [chemical binding]; other site 291112001586 Q-loop/lid; other site 291112001587 ABC transporter signature motif; other site 291112001588 Walker B; other site 291112001589 D-loop; other site 291112001590 H-loop/switch region; other site 291112001591 TOBE domain; Region: TOBE_2; pfam08402 291112001592 HMMPfam hit to PF08402, TOBE domain, score 1.1e-13 291112001593 HMMPfam hit to PF03459, TOBE domain, score 4.8e-06 291112001594 HMMPfam hit to PF03459, TOBE domain, score 1.1e-08 291112001595 HMMSmart hit to SM00382, no description, score 6.1e-13 291112001596 HMMPfam hit to PF00005, ABC transporter, score 2.6e-58 291112001597 maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474 291112001598 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 291112001599 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 5.5e-37 291112001600 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112001601 dimer interface [polypeptide binding]; other site 291112001602 conserved gate region; other site 291112001603 putative PBP binding loops; other site 291112001604 ABC-ATPase subunit interface; other site 291112001605 7 probable transmembrane helices predicted for PAT2404 by TMHMM2.0 at aa 15-34, 41-58, 73-95, 281-303, 318-340, 376-398 and 488-510 291112001606 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.4e-14 291112001607 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 291112001608 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112001609 dimer interface [polypeptide binding]; other site 291112001610 conserved gate region; other site 291112001611 putative PBP binding loops; other site 291112001612 ABC-ATPase subunit interface; other site 291112001613 6 probable transmembrane helices predicted for PAT2405 by TMHMM2.0 at aa 13-35, 89-111, 124-143, 153-175, 206-228 and 258-280 291112001614 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.3e-16 291112001615 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368 291112001616 Sulfatase; Region: Sulfatase; cl17466 291112001617 HMMPfam hit to PF00884, Sulfatase, score 1.7e-22 291112001618 5 probable transmembrane helices predicted for PAT2406 by TMHMM2.0 at aa 13-35, 55-77, 90-112, 143-165 and 178-200 291112001619 Arginase-like amidino hydrolase family; Region: Arginase-like_1; cd09999 291112001620 active site 291112001621 Mn binding site [ion binding]; other site 291112001622 1 probable transmembrane helix predicted for PAT2411 by TMHMM2.0 at aa 5-27 291112001623 4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052 291112001624 4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640 291112001625 HMMPfam hit to PF02446, 4-alpha-glucanotransferase, score 5.4e-196 291112001626 maltodextrin phosphorylase; Provisional; Region: PRK14985 291112001627 This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300 291112001628 active site pocket [active] 291112001629 HMMPfam hit to PF00343, Carbohydrate phosphorylase, score 0 291112001630 transcriptional regulator MalT; Provisional; Region: PRK04841 291112001631 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112001632 DNA binding residues [nucleotide binding] 291112001633 HMMSmart hit to SM00421, no description, score 2e-21 291112001634 bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102 291112001635 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112001636 putative substrate translocation pore; other site 291112001637 HMMPfam hit to PF00083, Sugar (and other) transporter, score 0.00011 291112001638 12 probable transmembrane helices predicted for PAT2416 by TMHMM2.0 at aa 7-29, 39-61, 70-89, 94-116, 129-151, 156-178, 205-227, 237-259, 271-293, 306-328, 335-357 and 367-386 291112001639 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.3e-46 291112001640 Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992 291112001641 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 291112001642 inhibitor-cofactor binding pocket; inhibition site 291112001643 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112001644 catalytic residue [active] 291112001645 HMMPfam hit to PF00202, Aminotransferase class-III, score 2.5e-63 291112001646 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 291112001647 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 291112001648 NAD(P) binding site [chemical binding]; other site 291112001649 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 3.7e-41 291112001650 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.2e-06 291112001651 beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009 291112001652 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112001653 motif II; other site 291112001654 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4.6e-14 291112001655 12 probable transmembrane helices predicted for PAT2420 by TMHMM2.0 at aa 13-35, 50-72, 79-101, 106-128, 140-162, 166-188, 200-222, 237-259, 272-289, 293-315, 327-349 and 353-375 291112001656 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 9.8e-20 291112001657 Protein of unknown function (DUF1349); Region: DUF1349; pfam07081 291112001658 HMMPfam hit to PF07081, Protein of unknown function (DUF1349), score 4.2e-79 291112001659 HMMPfam hit to PF02018, Carbohydrate binding domain, score 0.0016 291112001660 thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240 291112001661 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112001662 FeS/SAM binding site; other site 291112001663 Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968 291112001664 HMMPfam hit to PF06968, Biotin and Thiamin Synthesis associated d, score 9.9e-37 291112001665 HMMPfam hit to PF04055, Radical SAM superfamily, score 3.8e-09 291112001666 Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728 291112001667 ThiS interaction site; other site 291112001668 putative active site [active] 291112001669 tetramer interface [polypeptide binding]; other site 291112001670 HMMPfam hit to PF05690, Thiazole biosynthesis protein ThiG, score 1.7e-166 291112001671 ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565 291112001672 thiS-thiF/thiG interaction site; other site 291112001673 HMMPfam hit to PF02597, ThiS family, score 1.9e-17 291112001674 molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690 291112001675 ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757 291112001676 ATP binding site [chemical binding]; other site 291112001677 substrate interface [chemical binding]; other site 291112001678 HMMPfam hit to PF05237, MoeZ/MoeB domain, score 1.7e-38 291112001679 HMMPfam hit to PF00899, ThiF family, score 1.4e-60 291112001680 Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564 291112001681 thiamine phosphate binding site [chemical binding]; other site 291112001682 active site 291112001683 pyrophosphate binding site [ion binding]; other site 291112001684 HMMPfam hit to PF02581, Thiamine monophosphate synthase/TENI, score 7.9e-74 291112001685 thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284 291112001686 ThiC-associated domain; Region: ThiC-associated; pfam13667 291112001687 Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422 291112001688 HMMPfam hit to PF01964, ThiC family, score 0 291112001689 H+ Antiporter protein; Region: 2A0121; TIGR00900 291112001690 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112001691 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1e-12 291112001692 10 probable transmembrane helices predicted for PAT2431 by TMHMM2.0 at aa 15-32, 39-61, 71-88, 95-117, 158-180, 215-237, 247-269, 282-304, 340-362 and 369-391 291112001693 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 291112001694 Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560 291112001695 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 291112001696 NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241 291112001697 NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296 291112001698 NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297 291112001699 NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429 291112001700 putative NADH binding site [chemical binding]; other site 291112001701 putative active site [active] 291112001702 nudix motif; other site 291112001703 putative metal binding site [ion binding]; other site 291112001704 HMMPfam hit to PF00293, NUDIX domain, score 3e-19 291112001705 Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717 291112001706 substrate binding site [chemical binding]; other site 291112001707 active site 291112001708 HMMPfam hit to PF01208, Uroporphyrinogen decarboxylase (URO-D), score 8.4e-203 291112001709 Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559 291112001710 Active_site [active] 291112001711 HMMPfam hit to PF04493, Endonuclease V, score 4.6e-93 291112001712 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068 291112001713 HMMPfam hit to PF04222, Protein of unknown function, DUF, score 5.3e-140 291112001714 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 291112001715 IHF dimer interface [polypeptide binding]; other site 291112001716 IHF - DNA interface [nucleotide binding]; other site 291112001717 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 1.3e-51; HMMSmart hit to SM00411, no description, score 9.8e-46 291112001718 Protein of unknown function (DUF1481); Region: DUF1481; pfam07356 291112001719 HMMPfam hit to PF07356, Protein of unknown function (DUF1481), score 9.3e-89 291112001720 1 probable transmembrane helix predicted for PAT2440 by TMHMM2.0 at aa 13-31 291112001721 phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885 291112001722 Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844 291112001723 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071 291112001724 Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843 291112001725 HMMPfam hit to PF02843, Phosphoribosylglycinamide synthetase, C d, score 4.4e-48 291112001726 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase, ATP, score 6.5e-133 291112001727 HMMPfam hit to PF02655, ATP-grasp domain, score 0.00014 291112001728 HMMPfam hit to PF02844, Phosphoribosylglycinamide synthetase, N d, score 9.1e-61 291112001729 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881 291112001730 Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates...; Region: IMPCH; cd01421 291112001731 purine monophosphate binding site [chemical binding]; other site 291112001732 dimer interface [polypeptide binding]; other site 291112001733 putative catalytic residues [active] 291112001734 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798 291112001735 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362 291112001736 HMMPfam hit to PF01808, AICARFT/IMPCHase bienzyme, score 1.6e-205 291112001737 HMMPfam hit to PF02142, MGS-like domain, score 2.1e-62 291112001738 Homeodomain-like domain; Region: HTH_32; pfam13565 291112001739 homoserine O-succinyltransferase; Provisional; Region: PRK05368 291112001740 Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131 291112001741 proposed active site lysine [active] 291112001742 conserved cys residue [active] 291112001743 HMMPfam hit to PF04204, Homoserine O-succinyltransferase, score 1.4e-212 291112001744 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112001745 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 2.7e-48 291112001746 3 probable transmembrane helices predicted for PAT2450 by TMHMM2.0 at aa 13-35, 40-62 and 75-97 291112001747 1 probable transmembrane helix predicted for PAT2451 by TMHMM2.0 at aa 134-156 291112001748 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727 291112001749 malate synthase A; Region: malate_syn_A; TIGR01344 291112001750 active site 291112001751 HMMPfam hit to PF01274, Malate synthase, score 0 291112001752 Region 11 291112001753 isocitrate lyase; Provisional; Region: PRK15063 291112001754 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 291112001755 tetramer interface [polypeptide binding]; other site 291112001756 active site 291112001757 Mg2+/Mn2+ binding site [ion binding]; other site 291112001758 HMMPfam hit to PF00463, Isocitrate lyase family, score 1.3e-266 291112001759 bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946 291112001760 Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579 291112001761 HMMPfam hit to PF06315, Isocitrate dehydrogenase kinase/phosphatase, score 0 291112001762 transcriptional repressor IclR; Provisional; Region: PRK11569 291112001763 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 291112001764 Bacterial transcriptional regulator; Region: IclR; pfam01614 291112001765 HMMPfam hit to PF01614, Bacterial transcriptional regulator, score 4.6e-52 291112001766 HMMSmart hit to SM00346, no description, score 8.7e-33 291112001767 Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876 291112001768 Peptidase family M28; Region: Peptidase_M28; pfam04389 291112001769 metal binding site [ion binding]; metal-binding site 291112001770 5 probable transmembrane helices predicted for PAT2460 by TMHMM2.0 at aa 17-39, 371-393, 414-436, 456-478 and 485-507 291112001771 HMMPfam hit to PF04389, Peptidase family M28, score 6.9e-53 291112001772 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 0.00057 291112001773 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112001774 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883 291112001775 nucleophilic elbow; other site 291112001776 catalytic triad; other site 291112001777 3 probable transmembrane helices predicted for PAT2462 by TMHMM2.0 at aa 7-26, 36-55 and 68-90 291112001778 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 291112001779 Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992 291112001780 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 291112001781 inhibitor-cofactor binding pocket; inhibition site 291112001782 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112001783 catalytic residue [active] 291112001784 Predicted dehydrogenase [General function prediction only]; Region: COG5322 291112001785 NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226 291112001786 NAD(P) binding pocket [chemical binding]; other site 291112001787 HMMPfam hit to PF00202, Aminotransferase class-III, score 3.9e-43 291112001788 Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924 291112001789 Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849 291112001790 Domain of unknown function (DUF1788); Region: DUF1788; pfam08747 291112001791 Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002 291112001792 Methyltransferase domain; Region: Methyltransf_26; pfam13659 291112001793 Methyltransferase domain; Region: Methyltransf_26; pfam13659 291112001794 TIGR02687 family protein; Region: TIGR02687 291112001795 PglZ domain; Region: PglZ; pfam08665 291112001796 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 291112001797 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112001798 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4.4e-15 291112001799 Predicted O-methyltransferase [General function prediction only]; Region: COG4122 291112001800 Methyltransferase domain; Region: Methyltransf_24; pfam13578 291112001801 HMMPfam hit to PF01596, O-methyltransferase, score 8.3e-09 291112001802 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112001803 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112001804 non-specific DNA binding site [nucleotide binding]; other site 291112001805 salt bridge; other site 291112001806 sequence-specific DNA binding site [nucleotide binding]; other site 291112001807 HMMSmart hit to SM00530, no description, score 4.2e-10 291112001808 HMMPfam hit to PF01381, Helix-turn-helix, score 9.5e-11 291112001809 HipA N-terminal domain; Region: Couple_hipA; cl11853 291112001810 Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127 291112001811 Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139 291112001812 hypothetical protein; Reviewed; Region: PRK09588 291112001813 HMMPfam hit to PF01139, Uncharacterized protein family UPF0027, score 6.1e-180 291112001814 acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591 291112001815 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 291112001816 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 291112001817 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 291112001818 Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511 291112001819 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 291112001820 carboxyltransferase (CT) interaction site; other site 291112001821 biotinylation site [posttranslational modification]; other site 291112001822 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 6.9e-15 291112001823 HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 5.9e-59 291112001824 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 2.1e-104 291112001825 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase,, score 0.00032 291112001826 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 4.8e-45 291112001827 Allophanate hydrolase subunit 1; Region: AHS1; pfam02682 291112001828 Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049 291112001829 Allophanate hydrolase subunit 2; Region: AHS2; smart00797 291112001830 HMMPfam hit to PF02626, Allophanate hydrolase subunit, score 1.8e-58 291112001831 HMMPfam hit to PF02682, Allophanate hydrolase subunit, score 1.9e-52 291112001832 LamB/YcsF family of lactam utilization protein; Region: LamB_YcsF_like; cd10787 291112001833 putative active site [active] 291112001834 HMMPfam hit to PF03746, LamB/YcsF family, score 1.1e-140 291112001835 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914 291112001836 11 probable transmembrane helices predicted for PAT2482 by TMHMM2.0 at aa 7-26, 31-53, 74-96, 106-128, 141-160, 180-202, 223-245, 277-299, 311-333, 337-359 and 372-389 291112001837 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 291112001838 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112001839 Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210 291112001840 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112001841 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112001842 Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829 291112001843 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112001844 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112001845 acyl-activating enzyme (AAE) consensus motif; other site 291112001846 AMP binding site [chemical binding]; other site 291112001847 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112001848 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.8e-85 291112001849 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.8e-10 291112001850 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112001851 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 291112001852 active site 291112001853 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 291112001854 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 291112001855 NAD(P) binding site [chemical binding]; other site 291112001856 This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822 291112001857 active site 291112001858 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112001859 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112001860 thioester reductase domain; Region: Thioester-redct; TIGR01746 291112001861 extended (e) SDRs, subgroup 1; Region: SDR_e1; cd05235 291112001862 putative NAD(P) binding site [chemical binding]; other site 291112001863 active site 291112001864 putative substrate binding site [chemical binding]; other site 291112001865 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 6.1e-65 291112001866 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 9.9e-70 291112001867 HMMPfam hit to PF00698, Acyl transferase domain, score 3.8e-10 291112001868 HMMPfam hit to PF00106, short chain dehydrogenase, score 5.4e-11 291112001869 2 probable transmembrane helices predicted for PAT2493 by TMHMM2.0 at aa 1042-1061 and 1187-1209 291112001870 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1e-15 291112001871 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.1e-16 291112001872 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 3.4e-06 291112001873 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 0.00041 291112001874 HMMPfam hit to PF07993, Male sterility protein, score 1.2e-68 291112001875 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112001876 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112001877 acyl-activating enzyme (AAE) consensus motif; other site 291112001878 AMP binding site [chemical binding]; other site 291112001879 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112001880 Condensation domain; Region: Condensation; pfam00668 291112001881 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112001882 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112001883 acyl-activating enzyme (AAE) consensus motif; other site 291112001884 AMP binding site [chemical binding]; other site 291112001885 active site 291112001886 CoA binding site [chemical binding]; other site 291112001887 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112001888 Condensation domain; Region: Condensation; pfam00668 291112001889 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112001890 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.8e-111 291112001891 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.8e-08 291112001892 HMMPfam hit to PF00668, Condensation domain, score 8.6e-23 291112001893 HMMPfam hit to PF00501, AMP-binding enzyme, score 5.4e-101 291112001894 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.1e-15 291112001895 HMMPfam hit to PF00668, Condensation domain, score 1.4e-20 291112001896 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 291112001897 active site 291112001898 catalytic residues [active] 291112001899 metal binding site [ion binding]; metal-binding site 291112001900 HMMPfam hit to PF01327, Polypeptide deformylase, score 7.4e-62 291112001901 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112001902 S-adenosylmethionine binding site [chemical binding]; other site 291112001903 HMMPfam hit to PF08241, Methyltransferase domain, score 5.9e-12 291112001904 HMMPfam hit to PF08242, Methyltransferase domain, score 8.3e-14 291112001905 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112001906 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112001907 non-specific DNA binding site [nucleotide binding]; other site 291112001908 salt bridge; other site 291112001909 sequence-specific DNA binding site [nucleotide binding]; other site 291112001910 HMMSmart hit to SM00530, no description, score 4.8e-14 291112001911 HMMPfam hit to PF01381, Helix-turn-helix, score 2.6e-15 291112001912 Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423 291112001913 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112001914 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112001915 non-specific DNA binding site [nucleotide binding]; other site 291112001916 salt bridge; other site 291112001917 sequence-specific DNA binding site [nucleotide binding]; other site 291112001918 HMMSmart hit to SM00530, no description, score 1.5e-15 291112001919 HMMPfam hit to PF01381, Helix-turn-helix, score 6.5e-17 291112001920 Acyl transferase domain; Region: Acyl_transf_1; cl08282 291112001921 Cupin domain; Region: Cupin_2; pfam07883 291112001922 HMMPfam hit to PF00190, Cupin, score 0.0049 291112001923 HMMPfam hit to PF07883, Cupin domain, score 6.9e-10 291112001924 Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483 291112001925 catalytic motif [active] 291112001926 Catalytic residue [active] 291112001927 PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989 291112001928 putative glycosyl transferase; Provisional; Region: PRK10073 291112001929 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 291112001930 active site 291112001931 HMMPfam hit to PF00535, Glycosyl transferase family, score 1.4e-32 291112001932 nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651 291112001933 active site 291112001934 tetramer interface [polypeptide binding]; other site 291112001935 HMMPfam hit to PF01156, Inosine-uridine preferring nucleoside hy, score 1.3e-162 291112001936 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112001937 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112001938 DNA binding residues [nucleotide binding] 291112001939 dimerization interface [polypeptide binding]; other site 291112001940 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.5e-22; HMMSmart hit to SM00421, no description, score 5.5e-22 291112001941 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 291112001942 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 291112001943 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.2e-79 291112001944 Protein of unknown function (DUF861); Region: Cupin_3; cl17594 291112001945 HMMPfam hit to PF05899, Protein of unknown function (DUF861), score 2.9e-21 291112001946 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 291112001947 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 291112001948 NAD(P) binding site [chemical binding]; other site 291112001949 catalytic residues [active] 291112001950 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 7e-206 291112001951 Domain of unknown function (DUF1795); Region: DUF1795; pfam08786 291112001952 2 probable transmembrane helices predicted for PAT2511 by TMHMM2.0 at aa 15-37 and 40-62 291112001953 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112001954 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112001955 DNA binding residues [nucleotide binding] 291112001956 dimerization interface [polypeptide binding]; other site 291112001957 HMMSmart hit to SM00421, no description, score 3.5e-17 291112001958 HMMPfam hit to PF08281, Sigma-70, region, score 0.0025 291112001959 1 probable transmembrane helix predicted for PAT2514 by TMHMM2.0 at aa 13-35 291112001960 Amino acid permease; Region: AA_permease_2; pfam13520 291112001961 13 probable transmembrane helices predicted for PAT2515 by TMHMM2.0 at aa 15-37, 44-63, 73-95, 102-124, 139-161, 168-190, 205-224, 237-259, 302-324, 345-364, 374-396, 409-430 and 440-462 291112001962 HMMPfam hit to PF00324, Amino acid permease, score 1.6e-06 291112001963 Protein of unknown function (DUF3156); Region: DUF3156; pfam11354 291112001964 Aromatic ring hydroxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2368 291112001965 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 291112001966 4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241 291112001967 HMMPfam hit to PF03241, 4-hydroxyphenylacetate 3-hydroxylase family, score 1.2e-93 291112001968 enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439 291112001969 Domain of unknown function (DUF3327); Region: DUF3327; pfam11806 291112001970 Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819 291112001971 HMMPfam hit to PF00756, Putative esterase, score 1.3e-21 291112001972 alkaline phosphatase; Provisional; Region: PRK10518 291112001973 Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016 291112001974 active site 291112001975 dimer interface [polypeptide binding]; other site 291112001976 1 probable transmembrane helix predicted for PAT2518 by TMHMM2.0 at aa 9-28 291112001977 HMMPfam hit to PF00245, Alkaline phosphatase, score 8.3e-118 291112001978 HMMSmart hit to SM00098, no description, score 2.9e-171 291112001979 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 291112001980 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 4.9e-16 291112001981 Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192 291112001982 Carbamoyltransferase; Region: CmcH_NodU; pfam02543 291112001983 HMMPfam hit to PF02543, Carbamoyltransferase, score 1.8e-120 291112001984 GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472 291112001985 3 probable transmembrane helices predicted for PAT2523 by TMHMM2.0 at aa 12-34, 44-58 and 65-87 291112001986 16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489 291112001987 Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468 291112001988 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112001989 S-adenosylmethionine binding site [chemical binding]; other site 291112001990 HMMPfam hit to PF05175, Methyltransferase small domain, score 1.6e-92 291112001991 HMMPfam hit to PF08242, Methyltransferase domain, score 1.2e-06 291112001992 HMMPfam hit to PF08468, Methyltransferase small domain N-term, score 2.6e-89 291112001993 DNA polymerase III subunit psi; Validated; Region: PRK06856 291112001994 HMMPfam hit to PF03603, DNA polymerase III psi subunit, score 1.2e-22 291112001995 ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491 291112001996 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112001997 Coenzyme A binding pocket [chemical binding]; other site 291112001998 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.1e-24 291112001999 peptide chain release factor 3; Provisional; Region: prfC; PRK00741 291112002000 Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169 291112002001 G1 box; other site 291112002002 putative GEF interaction site [polypeptide binding]; other site 291112002003 GTP/Mg2+ binding site [chemical binding]; other site 291112002004 Switch I region; other site 291112002005 G2 box; other site 291112002006 G3 box; other site 291112002007 Switch II region; other site 291112002008 G4 box; other site 291112002009 G5 box; other site 291112002010 RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689 291112002011 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 5.5e-59 291112002012 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.2e-09 291112002013 periplasmic protein; Provisional; Region: PRK10568 291112002014 BON domain; Region: BON; pfam04972 291112002015 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 5e-13; HMMSmart hit to SM00749, no description, score 1e-07 291112002016 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667 291112002017 Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208 291112002018 active site 291112002019 nucleophile elbow; other site 291112002020 HMMPfam hit to PF01734, Patatin-like phospholipase, score 7e-24 291112002021 TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310 291112002022 active site 291112002023 HMMPfam hit to PF01026, TatD related DNase, score 1.6e-93 291112002024 Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972 291112002025 Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773 291112002026 Nucleoside recognition; Region: Gate; pfam07670 291112002027 Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662 291112002028 HMMPfam hit to PF01773, Na+ dependent nucleoside transporter N, score 1.3e-30 291112002029 10 probable transmembrane helices predicted for PAT2532 by TMHMM2.0 at aa 4-22, 29-51, 96-118, 173-195, 199-221, 266-288, 298-315, 322-344, 364-386 and 405-424 291112002030 HMMPfam hit to PF07670, Nucleoside recognition, score 1.3e-18 291112002031 HMMPfam hit to PF07662, Na+ dependent nucleoside transporter C, score 4.5e-106 291112002032 PAAR motif; Region: PAAR_motif; pfam05488 291112002033 1 probable transmembrane helix predicted for PAT2535 by TMHMM2.0 at aa 10-32 291112002034 PAAR motif; Region: PAAR_motif; pfam05488 291112002035 HMMPfam hit to PF05488, PAAR motif, score 0.17 291112002036 HMMPfam hit to PF05488, PAAR motif, score 0.23 291112002037 PAAR motif; Region: PAAR_motif; pfam05488 291112002038 PAAR motif; Region: PAAR_motif; pfam05488 291112002039 PAAR motif; Region: PAAR_motif; pfam05488 291112002040 KilA-N domain; Region: KilA-N; pfam04383 291112002041 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112002042 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112002043 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112002044 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112002045 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733 291112002046 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 1.3e-38 291112002047 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959 291112002048 intersubunit interface [polypeptide binding]; other site 291112002049 active site 291112002050 catalytic residue [active] 291112002051 HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 1.8e-70 291112002052 thymidine phosphorylase; Reviewed; Region: deoA; PRK05820 291112002053 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 291112002054 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 291112002055 Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941 291112002056 HMMPfam hit to PF02885, Glycosyl transferase family, helical, score 4.8e-19 291112002057 HMMPfam hit to PF00591, Glycosyl transferase family, a/b doma, score 8.9e-70 291112002058 HMMPfam hit to PF07831, Pyrimidine nucleoside phosphorylase C, score 3.8e-23 291112002059 phosphopentomutase; Provisional; Region: PRK05362 291112002060 Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676 291112002061 HMMPfam hit to PF08342, Phosphopentomutase N-terminal, score 7.3e-67 291112002062 HMMPfam hit to PF01676, Metalloenzyme superfamily, score 1.5e-44 291112002063 purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819 291112002064 Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820 291112002065 HMMPfam hit to PF01048, Phosphorylase family, score 9.3e-110 291112002066 Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053 291112002067 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 291112002068 homodimer interface [polypeptide binding]; other site 291112002069 substrate-cofactor binding pocket; other site 291112002070 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112002071 catalytic residue [active] 291112002072 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 1.6e-234 291112002073 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 291112002074 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 291112002075 dimer interface [polypeptide binding]; other site 291112002076 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112002077 catalytic residue [active] 291112002078 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream. The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609 291112002079 FOG: CBS domain [General function prediction only]; Region: COG0517 291112002080 HMMPfam hit to PF00571, CBS domain pair, score 5.6e-21 291112002081 HMMSmart hit to SM00116, no description, score 9.4 291112002082 HMMSmart hit to SM00116, no description, score 0.092 291112002083 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 3.6e-95 291112002084 hypothetical protein; Provisional; Region: PRK11246 291112002085 2 probable transmembrane helices predicted for PAT2557 by TMHMM2.0 at aa 13-32 and 164-186 291112002086 phosphoserine phosphatase; Provisional; Region: serB; PRK11133 291112002087 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 291112002088 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112002089 motif II; other site 291112002090 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.8e-25 291112002091 HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 0.0001 291112002092 DNA repair protein RadA; Region: sms; TIGR00416 291112002093 Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121 291112002094 Walker A motif/ATP binding site; other site 291112002095 ATP binding site [chemical binding]; other site 291112002096 Walker B motif; other site 291112002097 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 291112002098 HMMSmart hit to SM00382, no description, score 1.2e-08 291112002099 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112002100 non-specific DNA binding site [nucleotide binding]; other site 291112002101 salt bridge; other site 291112002102 bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099 291112002103 sequence-specific DNA binding site [nucleotide binding]; other site 291112002104 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 291112002105 active site 291112002106 nucleotide binding site [chemical binding]; other site 291112002107 HIGH motif; other site 291112002108 KMSKS motif; other site 291112002109 Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172 291112002110 HMMSmart hit to SM00530, no description, score 1.5e-05 291112002111 HMMPfam hit to PF01381, Helix-turn-helix, score 9.7e-08 291112002112 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112002113 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 291112002114 Walker A/P-loop; other site 291112002115 ATP binding site [chemical binding]; other site 291112002116 Q-loop/lid; other site 291112002117 ABC transporter signature motif; other site 291112002118 Walker B; other site 291112002119 D-loop; other site 291112002120 H-loop/switch region; other site 291112002121 HMMSmart hit to SM00382, no description, score 5.8e-07 291112002122 HMMPfam hit to PF00005, ABC transporter, score 6.9e-38 291112002123 putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819 291112002124 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112002125 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112002126 ABC transporter; Region: ABC_tran_2; pfam12848 291112002127 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112002128 HMMSmart hit to SM00382, no description, score 3.1e-11 291112002129 HMMPfam hit to PF00005, ABC transporter, score 2e-52 291112002130 HMMSmart hit to SM00382, no description, score 2.5e-08 291112002131 HMMPfam hit to PF00005, ABC transporter, score 1.6e-58 291112002132 1 probable transmembrane helix predicted for PAT2563 by TMHMM2.0 at aa 7-29 291112002133 lytic murein transglycosylase; Provisional; Region: PRK11619 291112002134 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 291112002135 N-acetyl-D-glucosamine binding site [chemical binding]; other site 291112002136 catalytic residue [active] 291112002137 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 4.7e-35 291112002138 Trp operon repressor; Provisional; Region: PRK01381 291112002139 HMMPfam hit to PF01371, Trp repressor protein, score 5.9e-39 291112002140 inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074 291112002141 HMMPfam hit to PF01931, Protein of unknown function DUF84, score 1.2e-55 291112002142 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 291112002143 catalytic core [active] 291112002144 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 1.3e-49 291112002145 right oriC-binding transcriptional activator; Provisional; Region: PRK15121 291112002146 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112002147 GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445 291112002148 HMMPfam hit to PF06445, Bacterial transcription activator, effect, score 7.4e-27 291112002149 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pro, score 2.1e-11 291112002150 HMMSmart hit to SM00342, no description, score 1.9e-31 291112002151 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix pro, score 3.8e-12 291112002152 hypothetical protein; Provisional; Region: PRK10756 291112002153 CreA protein; Region: CreA; pfam05981 291112002154 HMMPfam hit to PF05981, CreA protein, score 4.7e-89 291112002155 two-component response regulator; Provisional; Region: PRK11173 291112002156 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112002157 active site 291112002158 phosphorylation site [posttranslational modification] 291112002159 intermolecular recognition site; other site 291112002160 dimerization interface [polypeptide binding]; other site 291112002161 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112002162 DNA binding site [nucleotide binding] 291112002163 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 1.1e-17 291112002164 HMMPfam hit to PF00072, Response regulator receiver domain, score 7e-34 291112002165 HMMSmart hit to SM00448, no description, score 9.8e-37 291112002166 bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436 291112002167 AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257 291112002168 putative catalytic residues [active] 291112002169 putative nucleotide binding site [chemical binding]; other site 291112002170 putative aspartate binding site [chemical binding]; other site 291112002171 ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921 291112002172 dimer interface [polypeptide binding]; other site 291112002173 putative threonine allosteric regulatory site; other site 291112002174 ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922 291112002175 putative threonine allosteric regulatory site; other site 291112002176 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 291112002177 Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742 291112002178 HMMPfam hit to PF00696, Amino acid kinase family, score 1e-56 291112002179 HMMPfam hit to PF01842, ACT domain, score 3.7e-11 291112002180 HMMPfam hit to PF01842, ACT domain, score 2.6e-06 291112002181 HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding d, score 5.1e-37 291112002182 HMMPfam hit to PF00742, Homoserine dehydrogenase, score 7.7e-95 291112002183 homoserine kinase; Provisional; Region: PRK01212 291112002184 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 291112002185 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 291112002186 HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 2.8e-21 291112002187 HMMPfam hit to PF08544, GHMP kinases C terminal, score 6.3e-11 291112002188 Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498 291112002189 Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560 291112002190 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112002191 catalytic residue [active] 291112002192 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.1e-32 291112002193 hypothetical protein; Validated; Region: PRK02101 291112002194 HMMPfam hit to PF03883, Protein of unknown function (DUF328), score 1.1e-168 291112002195 H+ Antiporter protein; Region: 2A0121; TIGR00900 291112002196 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1e-08 291112002197 10 probable transmembrane helices predicted for PAT2575 by TMHMM2.0 at aa 10-32, 45-64, 79-101, 133-150, 155-177, 207-229, 251-273, 282-299, 304-323 and 358-380 291112002198 transaldolase-like protein; Provisional; Region: PTZ00411 291112002199 Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957 291112002200 active site 291112002201 dimer interface [polypeptide binding]; other site 291112002202 catalytic residue [active] 291112002203 HMMPfam hit to PF00923, Transaldolase, score 5.5e-181 291112002204 MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886 291112002205 MPT binding site; other site 291112002206 trimer interface [polypeptide binding]; other site 291112002207 HMMPfam hit to PF00994, Probable molybdopterin binding domain, score 1.1e-26 291112002208 galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720 291112002209 Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608 291112002210 dimer interface [polypeptide binding]; other site 291112002211 active site 291112002212 HMMPfam hit to PF01087, Galactose-1-phosphate uridyl transfer, score 1.2e-86 291112002213 HMMPfam hit to PF02744, Galactose-1-phosphate uridyl transfer, score 4.7e-88 291112002214 galactokinase; Provisional; Region: PRK05101 291112002215 Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509 291112002216 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 291112002217 HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 2.2e-15 291112002218 HMMPfam hit to PF08544, GHMP kinases C terminal, score 1.1e-12 291112002219 hypothetical protein; Provisional; Region: PRK10659 291112002220 HMMPfam hit to PF01184, GPR1/FUN34/yaaH family, score 5.3e-82 291112002221 6 probable transmembrane helices predicted for PAT2580 by TMHMM2.0 at aa 10-27, 32-54, 64-86, 99-118, 123-141 and 148-170 291112002222 molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290 291112002223 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 291112002224 nucleotide binding site [chemical binding]; other site 291112002225 HMMPfam hit to PF00012, Hsp70 protein, score 0 291112002226 chaperone protein DnaJ; Provisional; Region: PRK10767 291112002227 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 291112002228 HSP70 interaction site [polypeptide binding]; other site 291112002229 C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262 291112002230 substrate binding site [polypeptide binding]; other site 291112002231 Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719 291112002232 Zn binding sites [ion binding]; other site 291112002233 C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747 291112002234 dimer interface [polypeptide binding]; other site 291112002235 HMMSmart hit to SM00271, no description, score 1.5e-31 291112002236 HMMPfam hit to PF00226, DnaJ domain, score 1.6e-38 291112002237 HMMPfam hit to PF00684, DnaJ central domain (4 repeats), score 5.4e-45 291112002238 HMMPfam hit to PF01556, DnaJ C terminal region, score 4.6e-76 291112002239 Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966 291112002240 HMMPfam hit to PF04966, Carbohydrate-selective porin, OprB family, score 5e-72 291112002241 Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046 291112002242 beta-galactosidase; Region: BGL; TIGR03356 291112002243 HMMPfam hit to PF00232, Glycosyl hydrolase family, score 4.6e-206 291112002244 PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996 291112002245 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 291112002246 active site turn [active] 291112002247 phosphorylation site [posttranslational modification] 291112002248 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 291112002249 10 probable transmembrane helices predicted for PAT2585 by TMHMM2.0 at aa 118-140, 155-177, 182-204, 219-241, 261-283, 303-325, 370-392, 397-416, 421-440 and 445-467 291112002250 HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4.7e-32 291112002251 HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 1.3e-13 291112002252 transcriptional antiterminator BglG; Provisional; Region: PRK09772 291112002253 CAT RNA binding domain; Region: CAT_RBD; smart01061 291112002254 PRD domain; Region: PRD; pfam00874 291112002255 PRD domain; Region: PRD; pfam00874 291112002256 HMMPfam hit to PF03123, CAT RNA binding domain, score 8.6e-13 291112002257 HMMPfam hit to PF00874, PRD domain, score 1.6e-15 291112002258 HMMPfam hit to PF00874, PRD domain, score 5.6e-13 291112002259 PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995 291112002260 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 291112002261 active site turn [active] 291112002262 phosphorylation site [posttranslational modification] 291112002263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 291112002264 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 291112002265 HPr interaction site; other site 291112002266 glycerol kinase (GK) interaction site [polypeptide binding]; other site 291112002267 active site 291112002268 phosphorylation site [posttranslational modification] 291112002269 HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 4.9e-08 291112002270 HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 5.2e-24 291112002271 9 probable transmembrane helices predicted for PAT2587 by TMHMM2.0 at aa 104-126, 139-161, 171-190, 203-225, 240-262, 275-297, 319-341, 379-401 and 421-443 291112002272 HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 6.3e-55 291112002273 pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561 291112002274 HMMPfam hit to PF06965, Na+/H+ antiporter, score 9.1e-234 291112002275 11 probable transmembrane helices predicted for PAT2589 by TMHMM2.0 at aa 13-30, 58-77, 94-116, 126-145, 154-176, 180-202, 215-237, 257-279, 286-308, 328-350 and 363-385 291112002276 transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062 291112002277 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112002278 The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429 291112002279 putative dimerization interface [polypeptide binding]; other site 291112002280 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 5.4e-20 291112002281 HMMPfam hit to PF03466, LysR substrate binding domain, score 0.00029 291112002282 30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239 291112002283 HMMPfam hit to PF01649, Ribosomal protein S20, score 2.3e-42 291112002284 bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627 291112002285 FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064 291112002286 active site 291112002287 Riboflavin kinase; Region: Flavokinase; smart00904 291112002288 HMMPfam hit to PF06574, FAD synthetase, score 7.5e-86 291112002289 HMMPfam hit to PF01467, Cytidylyltransferase, score 0.0068 291112002290 HMMPfam hit to PF01687, Riboflavin kinase, score 3.3e-56 291112002291 isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743 291112002292 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 291112002293 active site 291112002294 HIGH motif; other site 291112002295 nucleotide binding site [chemical binding]; other site 291112002296 catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818 291112002297 active site 291112002298 KMSKS motif; other site 291112002299 Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960 291112002300 tRNA binding surface [nucleotide binding]; other site 291112002301 anticodon binding site; other site 291112002302 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 291112002303 HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 0 291112002304 HMMPfam hit to PF08264, Anticodon-binding domain, score 1.9e-57 291112002305 HMMPfam hit to PF06827, Zinc finger found in FPG and IleRS, score 4.3e-12 291112002306 lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376 291112002307 lipoprotein signal peptidase; Provisional; Region: PRK14787 291112002308 4 probable transmembrane helices predicted for PAT2594 by TMHMM2.0 at aa 12-31, 70-92, 99-121 and 136-158 291112002309 FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095 291112002310 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 291112002311 HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 2.8e-05 291112002312 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045 291112002313 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761 291112002314 HMMPfam hit to PF02401, LytB protein, score 4.2e-176 291112002315 Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289 291112002316 Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113 291112002317 Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173 291112002318 HMMPfam hit to PF01113, Dihydrodipicolinate reductase, N-terminus, score 3.7e-68 291112002319 HMMPfam hit to PF05173, Dihydrodipicolinate reductase, C-terminus, score 7.7e-79 291112002320 carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564 291112002321 Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097 291112002322 Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744 291112002323 catalytic site [active] 291112002324 subunit interface [polypeptide binding]; other site 291112002325 HMMPfam hit to PF00988, Carbamoyl-phosphate synthase small ch, score 8.7e-91 291112002326 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.2e-73 291112002327 carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294 291112002328 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 291112002329 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 291112002330 Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787 291112002331 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 291112002332 ATP-grasp domain; Region: ATP-grasp_4; cl17255 291112002333 Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424 291112002334 IMP binding site; other site 291112002335 dimer interface [polypeptide binding]; other site 291112002336 interdomain contacts; other site 291112002337 partial ornithine binding site; other site 291112002338 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 1.5e-62 291112002339 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 2.8e-144 291112002340 HMMPfam hit to PF02787, Carbamoyl-phosphate synthetase large c, score 3.4e-67 291112002341 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 1.4e-26 291112002342 HMMPfam hit to PF02655, ATP-grasp domain, score 0.0013 291112002343 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 1.1e-30 291112002344 HMMPfam hit to PF02222, ATP-grasp domain, score 0.0029 291112002345 HMMPfam hit to PF02142, MGS-like domain, score 1.9e-31 291112002346 LysE type translocator; Region: LysE; cl00565 291112002347 HMMPfam hit to PF01810, LysE type translocator, score 1.4e-34 291112002348 5 probable transmembrane helices predicted for PAT2601 by TMHMM2.0 at aa 5-27, 40-62, 77-96, 117-139 and 149-171 291112002349 Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262 291112002350 Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209 291112002351 folate binding site [chemical binding]; other site 291112002352 NADP+ binding site [chemical binding]; other site 291112002353 HMMPfam hit to PF00186, Dihydrofolate reductase, score 4.8e-49 291112002354 diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166 291112002355 Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422 291112002356 active site 291112002357 metal binding site [ion binding]; metal-binding site 291112002358 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 4.2e-17 291112002359 CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461 291112002360 HMMPfam hit to PF04379, Protein of unknown function (DUF525), score 6.5e-72 291112002361 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274 291112002362 Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030 291112002363 S-adenosylmethionine binding site [chemical binding]; other site 291112002364 HMMPfam hit to PF00398, Ribosomal RNA adenine dimethylase, score 1.6e-97 291112002365 HMMSmart hit to SM00650, no description, score 4.9e-84 291112002366 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232 291112002367 4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743 291112002368 HMMPfam hit to PF04166, Pyridoxal phosphate biosynthetic protein Pdx, score 3.5e-168 291112002369 peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770 291112002370 SurA N-terminal domain; Region: SurA_N; pfam09312 291112002371 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 291112002372 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 291112002373 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 8.2e-46 291112002374 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 9.1e-28 291112002375 LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761 291112002376 OstA-like protein; Region: OstA; pfam03968 291112002377 Organic solvent tolerance protein; Region: OstA_C; pfam04453 291112002378 HMMPfam hit to PF04453, Organic solvent tolerance protein, score 5.2e-129 291112002379 HMMPfam hit to PF03968, OstA-like protein, score 7.2e-56 291112002380 Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430 291112002381 N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316 291112002382 putative metal binding site [ion binding]; other site 291112002383 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 291112002384 1 probable transmembrane helix predicted for PAT2609 by TMHMM2.0 at aa 7-29 291112002385 HMMSmart hit to SM00271, no description, score 1.4e-14 291112002386 HMMPfam hit to PF00226, DnaJ domain, score 1.6e-05 291112002387 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 291112002388 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 291112002389 active site 291112002390 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 2.9e-58 291112002391 ATP-dependent helicase HepA; Validated; Region: PRK04914 291112002392 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112002393 ATP binding site [chemical binding]; other site 291112002394 putative Mg++ binding site [ion binding]; other site 291112002395 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112002396 nucleotide binding region [chemical binding]; other site 291112002397 ATP-binding site [chemical binding]; other site 291112002398 HMMSmart hit to SM00490, no description, score 1.6e-14 291112002399 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 3.1e-15 291112002400 HMMPfam hit to PF00176, SNF2 family N-terminal domain, score 7.7e-67 291112002401 HMMSmart hit to SM00487, no description, score 7.5e-20 291112002402 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 7.5e-06 291112002403 DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both...; Region: POLBc; cl10023 291112002404 Predicted permeases [General function prediction only]; Region: COG0679 291112002405 9 probable transmembrane helices predicted for PAT2613 by TMHMM2.0 at aa 4-21, 28-50, 65-87, 121-143, 158-180, 193-215, 220-242, 249-271 and 281-303 291112002406 HMMPfam hit to PF03547, Auxin Efflux Carrier, score 5.1e-11 291112002407 thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771 291112002408 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112002409 Walker A/P-loop; other site 291112002410 ATP binding site [chemical binding]; other site 291112002411 Q-loop/lid; other site 291112002412 ABC transporter signature motif; other site 291112002413 Walker B; other site 291112002414 D-loop; other site 291112002415 H-loop/switch region; other site 291112002416 HMMSmart hit to SM00382, no description, score 4.4e-18 291112002417 HMMPfam hit to PF00005, ABC transporter, score 4.7e-64 291112002418 thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433 291112002419 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112002420 dimer interface [polypeptide binding]; other site 291112002421 conserved gate region; other site 291112002422 putative PBP binding loops; other site 291112002423 ABC-ATPase subunit interface; other site 291112002424 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112002425 dimer interface [polypeptide binding]; other site 291112002426 conserved gate region; other site 291112002427 putative PBP binding loops; other site 291112002428 ABC-ATPase subunit interface; other site 291112002429 12 probable transmembrane helices predicted for PAT2615 by TMHMM2.0 at aa 13-35, 55-77, 90-112, 127-149, 201-223, 243-260, 292-311, 331-353, 373-395, 405-424, 462-484 and 508-525 291112002430 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8.1e-07 291112002431 thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205 291112002432 ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143 291112002433 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 0.00033 291112002434 Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671 291112002435 putative active site [active] 291112002436 Ap4A binding site [chemical binding]; other site 291112002437 nudix motif; other site 291112002438 putative metal binding site [ion binding]; other site 291112002439 HMMPfam hit to PF00293, NUDIX domain, score 2.9e-31 291112002440 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061 291112002441 Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065 291112002442 PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524 291112002443 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 291112002444 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 291112002445 HMMSmart hit to SM00065, no description, score 2.2e-24 291112002446 HMMPfam hit to PF01590, GAF domain, score 2.1e-26 291112002447 HMMPfam hit to PF05524, PEP-utilising enzyme, N-terminal, score 1.8e-34 291112002448 HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 2.9e-14 291112002449 HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 3.8e-129 291112002450 prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052 291112002451 HMMPfam hit to PF01790, Prolipoprotein diacylglyceryl transferase, score 2.7e-145 291112002452 7 probable transmembrane helices predicted for PAT2619 by TMHMM2.0 at aa 15-37, 58-80, 95-117, 130-147, 199-218, 225-243 and 258-280 291112002453 thymidylate synthase; Reviewed; Region: thyA; PRK01827 291112002454 Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351 291112002455 dimerization interface [polypeptide binding]; other site 291112002456 active site 291112002457 HMMPfam hit to PF00303, Thymidylate synthase, score 8.9e-155 291112002458 Predicted transcription regulator containing HTH domain [Transcription]; Region: COG5499 291112002459 HMMPfam hit to PF01381, Helix-turn-helix, score 1.3e-06 291112002460 Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912 291112002461 hypothetical protein; Provisional; Region: PRK10506 291112002462 Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830 291112002463 HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 0.00022 291112002464 1 probable transmembrane helix predicted for PAT2623 by TMHMM2.0 at aa 17-39 291112002465 hypothetical protein; Provisional; Region: PRK10557 291112002466 prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532 291112002467 Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063 291112002468 1 probable transmembrane helix predicted for PAT2624 by TMHMM2.0 at aa 7-29 291112002469 Protein of unknown function (DUF2509); Region: DUF2509; pfam10713 291112002470 1 probable transmembrane helix predicted for PAT2625 by TMHMM2.0 at aa 15-37 291112002471 hypothetical protein; Provisional; Region: PRK10332 291112002472 Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830 291112002473 Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528 291112002474 HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 0.00094 291112002475 1 probable transmembrane helix predicted for PAT2626 by TMHMM2.0 at aa 15-33 291112002476 exonuclease V subunit gamma; Provisional; Region: recC; PRK11069 291112002477 Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330 291112002478 HMMPfam hit to PF04257, Exodeoxyribonuclease V, gamma subunit, score 0 291112002479 protease3; Provisional; Region: PRK15101 291112002480 Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675 291112002481 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 291112002482 Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193 291112002483 HMMPfam hit to PF00675, Insulinase (Peptidase family M16), score 4.2e-44 291112002484 HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 2.1e-27 291112002485 HMMPfam hit to PF05193, Peptidase M16 inactive domain, score 2.6e-10 291112002486 exonuclease V subunit beta; Provisional; Region: recB; PRK10876 291112002487 PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705 291112002488 HMMPfam hit to PF00580, UvrD/REP helicase, score 1.5e-102 291112002489 exonuclease V subunit alpha; Provisional; Region: recD; PRK10875 291112002490 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983 291112002491 Family description; Region: UvrD_C_2; pfam13538 291112002492 HMMSmart hit to SM00382, no description, score 0.0051 291112002493 N-acetylglutamate synthase; Validated; Region: PRK05279 291112002494 AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237 291112002495 putative feedback inhibition sensing region; other site 291112002496 putative nucleotide binding site [chemical binding]; other site 291112002497 putative substrate binding site [chemical binding]; other site 291112002498 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112002499 Coenzyme A binding pocket [chemical binding]; other site 291112002500 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.4e-09 291112002501 HMMPfam hit to PF00696, Amino acid kinase family, score 1.5e-25 291112002502 1 probable transmembrane helix predicted for PAT2632 by TMHMM2.0 at aa 16-33 291112002503 AMIN domain; Region: AMIN; pfam11741 291112002504 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860 291112002505 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 291112002506 active site 291112002507 metal binding site [ion binding]; metal-binding site 291112002508 HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase, score 2.4e-102 291112002509 HMMSmart hit to SM00646, no description, score 1.4e-65 291112002510 2 probable transmembrane helices predicted for PAT2635 by TMHMM2.0 at aa 4-26 and 33-55 291112002511 murein transglycosylase A; Provisional; Region: mltA; PRK11162 291112002512 MltA specific insert domain; Region: MltA; pfam03562 291112002513 3D domain; Region: 3D; pfam06725 291112002514 HMMPfam hit to PF03562, MltA N-terminal domain, score 3.6e-90 291112002515 HMMPfam hit to PF06725, 3D domain, score 8.2e-34 291112002516 sulfur acceptor protein CsdL; Provisional; Region: PRK15116 291112002517 Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755 291112002518 putative ATP binding site [chemical binding]; other site 291112002519 putative substrate interface [chemical binding]; other site 291112002520 HMMPfam hit to PF00899, ThiF family, score 2.6e-62 291112002521 1 probable transmembrane helix predicted for PAT2637 by TMHMM2.0 at aa 236-258 291112002522 cysteine desulfurase, sulfur acceptor subunit CsdE; Region: FeS_syn_CsdE; TIGR03391 291112002523 HMMPfam hit to PF02657, Fe-S metabolism associated domain, score 3.2e-49 291112002524 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 291112002525 Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453 291112002526 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112002527 catalytic residue [active] 291112002528 HMMPfam hit to PF00266, Aminotransferase class-V, score 4.3e-173 291112002529 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 291112002530 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112002531 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 291112002532 dimerization interface [polypeptide binding]; other site 291112002533 substrate binding pocket [chemical binding]; other site 291112002534 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.4e-21 291112002535 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.3e-46 291112002536 hypothetical protein; Provisional; Region: PRK10873 291112002537 4 probable transmembrane helices predicted for PAT2641 by TMHMM2.0 at aa 5-27, 37-59, 66-88 and 98-120 291112002538 HMMPfam hit to PF04241, Protein of unknown function (DUF423), score 6.5e-39 291112002539 putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760 291112002540 FtsJ-like methyltransferase; Region: FtsJ; pfam01728 291112002541 Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria. They may be secreted into the medium via a mechanism found in gram-negative bacteria, that does not...; Region: ZnMc_serralysin_like; cd04277 291112002542 active site 291112002543 Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548 291112002544 HMMSmart hit to SM00235, no description, score 3.5e-16 291112002545 HMMPfam hit to PF00413, Matrixin, score 0.00056 291112002546 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 0.0045 291112002547 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 0.0022 291112002548 Protease inhibitor Inh; Region: Inh; pfam02974 291112002549 1 probable transmembrane helix predicted for PAT2644 by TMHMM2.0 at aa 5-27 291112002550 HMMPfam hit to PF02974, Protease inhibitor Inh, score 4.6e-36 291112002551 ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only]; Region: ArpD; COG4618 291112002552 ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246 291112002553 Walker A/P-loop; other site 291112002554 ATP binding site [chemical binding]; other site 291112002555 Q-loop/lid; other site 291112002556 ABC transporter signature motif; other site 291112002557 Walker B; other site 291112002558 D-loop; other site 291112002559 H-loop/switch region; other site 291112002560 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2.2e-05 291112002561 5 probable transmembrane helices predicted for PAT2645 by TMHMM2.0 at aa 21-43, 56-78, 127-149, 155-177 and 254-276 291112002562 HMMSmart hit to SM00382, no description, score 2e-11 291112002563 HMMPfam hit to PF00005, ABC transporter, score 2.8e-54 291112002564 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 291112002565 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112002566 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112002567 1 probable transmembrane helix predicted for PAT2646 by TMHMM2.0 at aa 24-46 291112002568 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.9e-64 291112002569 type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844 291112002570 1 probable transmembrane helix predicted for PAT2647 by TMHMM2.0 at aa 7-29 291112002571 HMMPfam hit to PF02321, Outer membrane efflux protein, score 3.8e-34 291112002572 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2.4e-49 291112002573 flap endonuclease-like protein; Provisional; Region: PRK09482 291112002574 PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859 291112002575 active site 291112002576 metal binding site 1 [ion binding]; metal-binding site 291112002577 putative 5' ssDNA interaction site; other site 291112002578 metal binding site 3; metal-binding site 291112002579 metal binding site 2 [ion binding]; metal-binding site 291112002580 H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898 291112002581 putative DNA binding site [nucleotide binding]; other site 291112002582 putative metal binding site [ion binding]; other site 291112002583 HMMPfam hit to PF01367, 5'-3' exonuclease, C-terminal SAM fold, score 1.6e-20 291112002584 HMMSmart hit to SM00475, no description, score 2.1e-91 291112002585 HMMSmart hit to SM00279, no description, score 9.6e-11 291112002586 HMMPfam hit to PF02739, 5'-3' exonuclease, N-terminal resolvase-, score 2.6e-16 291112002587 Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611 291112002588 Domain of unknown function (DUF3412); Region: DUF3412; pfam11892 291112002589 HMMPfam hit to PF03641, Possible lysine decarboxylase, score 3.4e-51 291112002590 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904 291112002591 7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792 291112002592 Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780 291112002593 HMMPfam hit to PF01227, GTP cyclohydrolase I, score 1e-08 291112002594 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112002595 active site 291112002596 motif I; other site 291112002597 motif II; other site 291112002598 HMMPfam hit to PF03767, HAD superfamily, subfamily IIIB (Acid, score 1.1e-60 291112002599 Predicted proline hydroxylase [Posttranslational modification, protein turnover, chaperones]; Region: EGL-9; COG3751 291112002600 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 291112002601 HMMSmart hit to SM00702, no description, score 0.00095 291112002602 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112002603 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079 291112002604 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112002605 homodimer interface [polypeptide binding]; other site 291112002606 catalytic residue [active] 291112002607 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.5e-21 291112002608 AAA domain; Region: AAA_17; pfam13207 291112002609 Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350 291112002610 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 291112002611 HMMSmart hit to SM00702, no description, score 0.0011 291112002612 Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229 291112002613 HMMPfam hit to PF04229, Uncharacterised protein family (UPF0157), score 8.7e-39 291112002614 HprK-related kinase B; Region: HprK_rel_B; TIGR04355 291112002615 Homeodomain-like domain; Region: HTH_23; pfam13384 291112002616 Winged helix-turn helix; Region: HTH_29; pfam13551 291112002617 Winged helix-turn helix; Region: HTH_33; pfam13592 291112002618 DDE superfamily endonuclease; Region: DDE_3; pfam13358 291112002619 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335 291112002620 acyl carrier protein; Provisional; Region: PRK07081 291112002621 peptide synthase; Provisional; Region: PRK12316 291112002622 HMMPfam hit to PF00668, Condensation domain, score 1.6e-06 291112002623 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 291112002624 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112002625 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112002626 Walker A/P-loop; other site 291112002627 ATP binding site [chemical binding]; other site 291112002628 Q-loop/lid; other site 291112002629 ABC transporter signature motif; other site 291112002630 Walker B; other site 291112002631 D-loop; other site 291112002632 H-loop/switch region; other site 291112002633 HMMSmart hit to SM00382, no description, score 3.5e-21 291112002634 HMMPfam hit to PF00005, ABC transporter, score 3.4e-52 291112002635 7 probable transmembrane helices predicted for PAT2666 by TMHMM2.0 at aa 44-66, 81-100, 107-129, 162-184, 191-213, 274-296 and 303-325 291112002636 Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019 291112002637 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261 291112002638 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 291112002639 catalytic residue [active] 291112002640 HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 3.1e-07 291112002641 HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, py, score 1.8e-10 291112002642 AMP-binding enzyme; Region: AMP-binding; pfam00501 291112002643 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112002644 active site 291112002645 AMP binding site [chemical binding]; other site 291112002646 acyl-activating enzyme (AAE) consensus motif; other site 291112002647 CoA binding site [chemical binding]; other site 291112002648 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.5e-20 291112002649 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 291112002650 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072 291112002651 This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288 291112002652 putative active site [active] 291112002653 Radical SAM superfamily; Region: Radical_SAM; pfam04055 291112002654 HMMSmart hit to SM00729, no description, score 3.8e-07 291112002655 HMMPfam hit to PF04055, Radical SAM superfamily, score 3.7e-16 291112002656 SecY interacting protein Syd; Provisional; Region: PRK04968 291112002657 HMMPfam hit to PF07348, Syd protein, score 1.3e-93 291112002658 tRNA pseudouridine synthase C; Region: DUF446; pfam04287 291112002659 HMMPfam hit to PF04287, Domain of unknown function, DUF446, score 1.3e-44 291112002660 Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564 291112002661 tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563 291112002662 probable active site [active] 291112002663 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.8e-50 291112002664 3 probable transmembrane helices predicted for PAT2676 by TMHMM2.0 at aa 10-32, 58-77 and 82-104 291112002665 flavodoxin; Provisional; Region: PRK08105 291112002666 HMMPfam hit to PF00258, Flavodoxin, score 4.5e-27 291112002667 hypothetical protein; Provisional; Region: PRK13677 291112002668 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830 291112002669 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350 291112002670 trimer interface [polypeptide binding]; other site 291112002671 active site 291112002672 substrate binding site [chemical binding]; other site 291112002673 CoA binding site [chemical binding]; other site 291112002674 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.37 291112002675 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 3.1 291112002676 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.81 291112002677 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 30 291112002678 PII uridylyl-transferase; Provisional; Region: PRK05007 291112002679 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 291112002680 metal binding triad; other site 291112002681 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335 291112002682 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 291112002683 Zn2+ binding site [ion binding]; other site 291112002684 Mg2+ binding site [ion binding]; other site 291112002685 ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900 291112002686 C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899 291112002687 HMMPfam hit to PF01842, ACT domain, score 1.6e-09 291112002688 HMMPfam hit to PF01842, ACT domain, score 0.00084 291112002689 HMMSmart hit to SM00471, no description, score 5.2e-12 291112002690 HMMPfam hit to PF01966, HD domain, score 9.8e-22 291112002691 HMMPfam hit to PF08335, GlnD PII-uridylyltransferase, score 4.1e-116 291112002692 HMMPfam hit to PF01909, Nucleotidyltransferase domain, score 5.5e-08 291112002693 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 291112002694 active site 291112002695 HMMPfam hit to PF00557, metallopeptidase family M24, score 3.8e-102 291112002696 Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425 291112002697 rRNA interaction site [nucleotide binding]; other site 291112002698 S8 interaction site; other site 291112002699 putative laminin-1 binding site; other site 291112002700 HMMPfam hit to PF00318, Ribosomal protein S2, score 8.4e-127 291112002701 elongation factor Ts; Provisional; Region: tsf; PRK09377 291112002702 UBA/TS-N domain; Region: UBA; pfam00627 291112002703 Elongation factor TS; Region: EF_TS; pfam00889 291112002704 Elongation factor TS; Region: EF_TS; pfam00889 291112002705 HMMPfam hit to PF00627, UBA/TS-N domain, score 6.9e-13 291112002706 HMMPfam hit to PF00889, Elongation factor TS, score 8.1e-103 291112002707 UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254 291112002708 putative nucleotide binding site [chemical binding]; other site 291112002709 uridine monophosphate binding site [chemical binding]; other site 291112002710 homohexameric interface [polypeptide binding]; other site 291112002711 HMMPfam hit to PF00696, Amino acid kinase family, score 1.2e-64 291112002712 ribosome recycling factor; Reviewed; Region: frr; PRK00083 291112002713 Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520 291112002714 hinge region; other site 291112002715 HMMPfam hit to PF01765, Ribosome recycling factor, score 2.3e-103 291112002716 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447 291112002717 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670 291112002718 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436 291112002719 DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288 291112002720 HMMPfam hit to PF02670, 1-deoxy-D-xylulose 5-phosphate reduct, score 1.4e-78 291112002721 HMMPfam hit to PF08436, 1-deoxy-D-xylulose 5-phosphate reduct, score 1.8e-60 291112002722 Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020 291112002723 Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475 291112002724 catalytic residue [active] 291112002725 putative FPP diphosphate binding site; other site 291112002726 putative FPP binding hydrophobic cleft; other site 291112002727 dimer interface [polypeptide binding]; other site 291112002728 putative IPP diphosphate binding site; other site 291112002729 HMMPfam hit to PF01255, Putative undecaprenyl diphosphate syntha, score 1.7e-128 291112002730 CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624 291112002731 CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575 291112002732 HMMPfam hit to PF01148, Cytidylyltransferase family, score 9.8e-82 291112002733 7 probable transmembrane helices predicted for PAT2688 by TMHMM2.0 at aa 7-24, 28-50, 57-74, 84-106, 118-140, 150-172 and 193-215 291112002734 zinc metallopeptidase RseP; Provisional; Region: PRK10779 291112002735 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 291112002736 active site 291112002737 PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989 291112002738 protein binding site [polypeptide binding]; other site 291112002739 PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989 291112002740 protein binding site [polypeptide binding]; other site 291112002741 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 291112002742 putative substrate binding region [chemical binding]; other site 291112002743 4 probable transmembrane helices predicted for PAT2689 by TMHMM2.0 at aa 5-27, 98-120, 377-399 and 427-446 291112002744 HMMPfam hit to PF02163, Peptidase family M50, score 5.3e-94 291112002745 HMMSmart hit to SM00228, no description, score 0.14 291112002746 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 1.1e-05 291112002747 HMMSmart hit to SM00228, no description, score 4.9e-08 291112002748 outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067 291112002749 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 291112002750 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 291112002751 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 291112002752 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 291112002753 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 291112002754 Surface antigen; Region: Bac_surface_Ag; pfam01103 291112002755 1 probable transmembrane helix predicted for PAT2690 by TMHMM2.0 at aa 7-26 291112002756 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 1.6e-10 291112002757 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 5.8e-16 291112002758 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 2.3e-19 291112002759 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 6.1e-15 291112002760 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 8.6e-21 291112002761 HMMPfam hit to PF01103, Surface antigen, score 4.9e-80 291112002762 periplasmic chaperone; Provisional; Region: PRK10780 291112002763 Outer membrane protein (OmpH-like); Region: OmpH; smart00935 291112002764 HMMPfam hit to PF03938, Outer membrane protein (OmpH-like), score 6.1e-58 291112002765 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892 291112002766 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613 291112002767 UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352 291112002768 trimer interface [polypeptide binding]; other site 291112002769 active site 291112002770 UDP-GlcNAc binding site [chemical binding]; other site 291112002771 lipid binding site [chemical binding]; lipid-binding site 291112002772 HMMPfam hit to PF04613, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-a, score 7.9e-48 291112002773 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.22 291112002774 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.0019 291112002775 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.23 291112002776 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.084 291112002777 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.38 291112002778 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.073 291112002779 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1 291112002780 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 16 291112002781 FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288 291112002782 HMMPfam hit to PF07977, FabA-like domain, score 1.7e-69 291112002783 UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289 291112002784 UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351 291112002785 active site 291112002786 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.001 291112002787 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 3.6 291112002788 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 20 291112002789 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.92 291112002790 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 12 291112002791 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.2 291112002792 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.13 291112002793 lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025 291112002794 ipid-A-disaccharide synthase; Provisional; Region: PRK14089 291112002795 HMMPfam hit to PF02684, Lipid-A-disaccharide synthetase, score 2e-196 291112002796 bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182 291112002797 RNA/DNA hybrid binding site [nucleotide binding]; other site 291112002798 active site 291112002799 HMMPfam hit to PF01351, Ribonuclease HII, score 8.5e-95 291112002800 DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673 291112002801 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433 291112002802 putative active site [active] 291112002803 putative PHP Thumb interface [polypeptide binding]; other site 291112002804 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 291112002805 generic binding surface II; other site 291112002806 generic binding surface I; other site 291112002807 HMMPfam hit to PF02811, PHP domain, score 4.2e-53 291112002808 HMMSmart hit to SM00481, no description, score 9.6e-26 291112002809 HMMPfam hit to PF07733, Bacterial DNA polymerase III alpha sub, score 0 291112002810 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 5.2e-11 291112002811 acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724 291112002812 acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198 291112002813 HMMPfam hit to PF03255, Acetyl co-enzyme A carboxylase carboxyltrans, score 3e-106 291112002814 tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660 291112002815 N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992 291112002816 Ligand Binding Site [chemical binding]; other site 291112002817 TilS substrate binding domain; Region: TilS; pfam09179 291112002818 TilS substrate C-terminal domain; Region: TilS_C; pfam11734 291112002819 HMMPfam hit to PF01171, PP-loop family, score 7.5e-91 291112002820 Rho-binding antiterminator; Provisional; Region: PRK11625 291112002821 HMMPfam hit to PF07073, Modulator of Rho-dependent transcription ter, score 1.6e-35 291112002822 lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523 291112002823 NlpE N-terminal domain; Region: NlpE; pfam04170 291112002824 HMMPfam hit to PF04170, Uncharacterized lipoprotein NlpE involved in, score 6.2e-28 291112002825 prolyl-tRNA synthetase; Provisional; Region: PRK09194 291112002826 Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779 291112002827 dimer interface [polypeptide binding]; other site 291112002828 motif 1; other site 291112002829 active site 291112002830 motif 2; other site 291112002831 INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334 291112002832 putative deacylase active site [active] 291112002833 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 291112002834 active site 291112002835 motif 3; other site 291112002836 ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861 291112002837 anticodon binding site; other site 291112002838 HMMPfam hit to PF03129, Anticodon binding domain, score 5.1e-25 291112002839 HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associa, score 2.3e-07 291112002840 HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 6.4e-66 291112002841 Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281 291112002842 homodimer interaction site [polypeptide binding]; other site 291112002843 cofactor binding site; other site 291112002844 HMMPfam hit to PF01980, Uncharacterised protein family UPF0066, score 4.4e-53 291112002845 outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781 291112002846 DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063 291112002847 lipoprotein, YaeC family; Region: TIGR00363 291112002848 HMMPfam hit to PF03180, NLPA lipoprotein, score 2.4e-135 291112002849 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112002850 dimer interface [polypeptide binding]; other site 291112002851 conserved gate region; other site 291112002852 ABC-ATPase subunit interface; other site 291112002853 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.3e-24 291112002854 5 probable transmembrane helices predicted for PAT2706 by TMHMM2.0 at aa 20-42, 55-77, 82-104, 144-166 and 181-203 291112002855 DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153 291112002856 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 291112002857 Walker A/P-loop; other site 291112002858 ATP binding site [chemical binding]; other site 291112002859 Q-loop/lid; other site 291112002860 ABC transporter signature motif; other site 291112002861 Walker B; other site 291112002862 D-loop; other site 291112002863 H-loop/switch region; other site 291112002864 This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930 291112002865 HMMSmart hit to SM00382, no description, score 9.4e-16 291112002866 HMMPfam hit to PF00005, ABC transporter, score 6.7e-77 291112002867 D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942 291112002868 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112002869 active site 291112002870 motif I; other site 291112002871 motif II; other site 291112002872 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 291112002873 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112002874 HMMPfam hit to PF01609, Transposase DDE domain, score 9.2e-14 291112002875 hypothetical protein; Provisional; Region: PRK05421 291112002876 putative catalytic site [active] 291112002877 putative metal binding site [ion binding]; other site 291112002878 putative phosphate binding site [ion binding]; other site 291112002879 putative catalytic site [active] 291112002880 putative phosphate binding site [ion binding]; other site 291112002881 putative metal binding site [ion binding]; other site 291112002882 HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 2.5e-16 291112002883 putative proline-specific permease; Provisional; Region: proY; PRK10580 291112002884 HMMPfam hit to PF00324, Amino acid permease, score 5.3e-133 291112002885 12 probable transmembrane helices predicted for PAT2713 by TMHMM2.0 at aa 21-38, 42-64, 93-115, 125-147, 154-176, 200-222, 243-265, 280-302, 332-354, 358-380, 400-422 and 427-449 291112002886 Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602 291112002887 putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322 291112002888 HMMPfam hit to PF04055, Radical SAM superfamily, score 0.0091 291112002889 Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1), 6-pyrovoyl...; Region: TFold; cl00263 291112002890 active site 291112002891 HMMPfam hit to PF01242, 6-pyruvoyl tetrahydropterin synthase, score 1.1e-67 291112002892 sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953 291112002893 Flavodoxin; Region: Flavodoxin_1; pfam00258 291112002894 Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199 291112002895 FAD binding pocket [chemical binding]; other site 291112002896 FAD binding motif [chemical binding]; other site 291112002897 catalytic residues [active] 291112002898 NAD binding pocket [chemical binding]; other site 291112002899 phosphate binding motif [ion binding]; other site 291112002900 beta-alpha-beta structure motif; other site 291112002901 HMMPfam hit to PF00258, Flavodoxin, score 5.8e-36 291112002902 HMMPfam hit to PF00667, FAD binding domain, score 1.1e-55 291112002903 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 1.1e-34 291112002904 sulfite reductase subunit beta; Provisional; Region: PRK13504 291112002905 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 291112002906 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 291112002907 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 8.3e-22 291112002908 HMMPfam hit to PF01077, Nitrite and sulphite reductase 4Fe-4S do, score 1.7e-56 291112002909 HMMPfam hit to PF03460, Nitrite/Sulfite reductase ferredoxin-lik, score 5.8e-19 291112002910 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175 291112002911 This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713 291112002912 Active Sites [active] 291112002913 HMMPfam hit to PF01507, Phosphoadenosine phosphosulfate reductase, score 3.1e-77 291112002914 Predicted nuclease of the RNAse H fold, HicB family [General function prediction only]; Region: HicB; COG4226 291112002915 siroheme synthase; Provisional; Region: cysG; PRK10637 291112002916 Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241 291112002917 Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414 291112002918 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 291112002919 active site 291112002920 SAM binding site [chemical binding]; other site 291112002921 homodimer interface [polypeptide binding]; other site 291112002922 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 1.4e-85 291112002923 sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039 291112002924 This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713 291112002925 Active Sites [active] 291112002926 HMMPfam hit to PF01507, Phosphoadenosine phosphosulfate reductase, score 4.7e-138 291112002927 Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170 291112002928 Switch II region; other site 291112002929 G4 box; other site 291112002930 G5 box; other site 291112002931 CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695 291112002932 TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095 291112002933 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 3.4e-08 291112002934 HMMPfam hit to PF03144, Elongation factor Tu domain, score 2.9e-11 291112002935 Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027 291112002936 ligand-binding site [chemical binding]; other site 291112002937 HMMPfam hit to PF01583, Adenylylsulphate kinase, score 1.5e-109 291112002938 cell division protein FtsB; Reviewed; Region: ftsB; PRK00888 291112002939 Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919 291112002940 HMMPfam hit to PF04977, Septum formation initiator, score 1.2e-31 291112002941 CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516 291112002942 substrate binding site; other site 291112002943 dimer interface; other site 291112002944 HMMPfam hit to PF01128, Uncharacterized protein family UPF000, score 4.5e-102 291112002945 HMMPfam hit to PF00483, Nucleotidyl transferase, score 0.003 291112002946 MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554 291112002947 homotrimer interaction site [polypeptide binding]; other site 291112002948 zinc binding site [ion binding]; other site 291112002949 CDP-binding sites; other site 291112002950 HMMPfam hit to PF02542, YgbB family, score 4.7e-98 291112002951 tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984 291112002952 Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575 291112002953 Permutation of conserved domain; other site 291112002954 active site 291112002955 Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130 291112002956 HMMPfam hit to PF01142, tRNA pseudouridine synthase D (TruD), score 5.9e-145 291112002957 5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346 291112002958 HMMPfam hit to PF01975, Survival protein SurE, score 5.5e-91 291112002959 protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312 291112002960 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112002961 S-adenosylmethionine binding site [chemical binding]; other site 291112002962 HMMPfam hit to PF01135, Protein-L-isoaspartate(D-aspartate) O-methyl, score 8e-96 291112002963 lipoprotein NlpD; Provisional; Region: nlpD; PRK10871 291112002964 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 291112002965 Peptidase family M23; Region: Peptidase_M23; pfam01551 291112002966 HMMSmart hit to SM00257, no description, score 7.8e-09 291112002967 HMMPfam hit to PF01476, LysM domain, score 2.4e-10 291112002968 HMMPfam hit to PF01551, Peptidase family M23, score 2.9e-45 291112002969 RNA polymerase sigma factor RpoS; Validated; Region: PRK05657 291112002970 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 291112002971 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 291112002972 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 291112002973 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 291112002974 DNA binding residues [nucleotide binding] 291112002975 HMMPfam hit to PF00140, Sigma-70 factor, region, score 9.8e-14 291112002976 HMMPfam hit to PF04542, Sigma-70 region, score 1.7e-25 291112002977 HMMPfam hit to PF04539, Sigma-70 region, score 1.3e-27 291112002978 HMMPfam hit to PF04545, Sigma-70, region, score 7.2e-18 291112002979 zinc-ribbon domain; Region: zf-ribbon_3; pfam13248 291112002980 Double zinc ribbon; Region: DZR; pfam12773 291112002981 1 probable transmembrane helix predicted for PAT1321 by TMHMM2.0 at aa 39-56 291112002982 Uncharacterized protein family UPF0547; Region: UPF0547; pfam10571 291112002983 2 probable transmembrane helices predicted for PAT1320 by TMHMM2.0 at aa 38-60 and 82-104 291112002984 MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910 291112002985 active site 291112002986 dinuclear metal binding site [ion binding]; other site 291112002987 dimerization interface [polypeptide binding]; other site 291112002988 HMMPfam hit to PF06175, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE), score 2.7e-162 291112002989 DNA mismatch repair protein MutS; Provisional; Region: PRK05399 291112002990 MutS domain I; Region: MutS_I; pfam01624 291112002991 MutS domain II; Region: MutS_II; pfam05188 291112002992 MutS domain III; Region: MutS_III; pfam05192 291112002993 ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284 291112002994 Walker A/P-loop; other site 291112002995 ATP binding site [chemical binding]; other site 291112002996 Q-loop/lid; other site 291112002997 ABC transporter signature motif; other site 291112002998 Walker B; other site 291112002999 D-loop; other site 291112003000 H-loop/switch region; other site 291112003001 HMMPfam hit to PF00488, MutS domain V, score 2.5e-169 291112003002 HMMSmart hit to SM00534, no description, score 1.9e-122 291112003003 HMMSmart hit to SM00533, no description, score 9.8e-105 291112003004 HMMPfam hit to PF05192, MutS domain III, score 6.9e-95 291112003005 HMMPfam hit to PF05190, MutS family domain IV, score 3.3e-41 291112003006 HMMPfam hit to PF05188, MutS domain II, score 1.4e-45 291112003007 HMMPfam hit to PF01624, MutS domain I, score 4.7e-75 291112003008 Family description; Region: VCBS; pfam13517 291112003009 HMMPfam hit to PF03991, no description, score 32 291112003010 HMMPfam hit to PF03991, no description, score 1.7 291112003011 Region 12 291112003012 DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411 291112003013 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220 291112003014 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 291112003015 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 8.1e-55 291112003016 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 1.4e-17 291112003017 HMMSmart hit to SM00420, no description, score 2.6e-14 291112003018 HMMPfam hit to PF08279, HTH domain, score 5.4e-06 291112003019 L-fuculokinase; Provisional; Region: PRK10331 291112003020 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 291112003021 nucleotide binding site [chemical binding]; other site 291112003022 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 6.2e-52 291112003023 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 8.8e-84 291112003024 L-fucose isomerase; Provisional; Region: fucI; PRK10991 291112003025 L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947 291112003026 hexamer (dimer of trimers) interface [polypeptide binding]; other site 291112003027 trimer interface [polypeptide binding]; other site 291112003028 substrate binding site [chemical binding]; other site 291112003029 Mn binding site [ion binding]; other site 291112003030 HMMPfam hit to PF02952, L-fucose isomerase, C-terminal domain, score 5.2e-112 291112003031 HMMPfam hit to PF07882, L-fucose isomerase, second N-terminal d, score 5.7e-119 291112003032 HMMPfam hit to PF07881, L-fucose isomerase, first N-terminal do, score 4e-121 291112003033 Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738 291112003034 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112003035 putative substrate translocation pore; other site 291112003036 12 probable transmembrane helices predicted for PAT1311 by TMHMM2.0 at aa 20-37, 57-79, 84-106, 116-138, 151-173, 202-224, 254-276, 286-308, 321-340, 345-367, 376-398 and 403-425 291112003037 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.5e-15 291112003038 L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193 291112003039 Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398 291112003040 intersubunit interface [polypeptide binding]; other site 291112003041 active site 291112003042 Zn2+ binding site [ion binding]; other site 291112003043 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 3.4e-69 291112003044 Fic/DOC family; Region: Fic; pfam02661 291112003045 HMMPfam hit to PF02661, Fic protein family, score 3.3e-07 291112003046 CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641 291112003047 DEAD-like helicases superfamily; Region: DEXDc; smart00487 291112003048 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 291112003049 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.0046 291112003050 CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669 291112003051 CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731 291112003052 CT1975-like protein; Region: Cas_CT1975; pfam09344 291112003053 CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704 291112003054 CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645 291112003055 CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727 291112003056 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112003057 1 probable transmembrane helix predicted for PAT1295 by TMHMM2.0 at aa 7-29 291112003058 1 probable transmembrane helix predicted for PAT1293 by TMHMM2.0 at aa 7-29 291112003059 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112003060 active site flap/lid [active] 291112003061 nucleophilic elbow; other site 291112003062 catalytic triad [active] 291112003063 HMMPfam hit to PF01764, Lipase (class 3), score 5.8e-21 291112003064 Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929 291112003065 HMMPfam hit to PF07929, Plasmid pRiA4b ORF-3-like protein, score 1.3e-84 291112003066 FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197 291112003067 Int/Topo IB signature motif; other site 291112003068 HMMPfam hit to PF00589, Phage integrase family, score 1.2e-43 291112003069 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112003070 2 probable transmembrane helices predicted for PAT1288 by TMHMM2.0 at aa 7-24 and 39-56 291112003071 HMMPfam hit to PF00419, Fimbrial protein, score 1.5e-47 291112003072 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112003073 1 probable transmembrane helix predicted for PAT1287 by TMHMM2.0 at aa 13-35 291112003074 HMMPfam hit to PF00419, Fimbrial protein, score 2.4e-22 291112003075 putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284 291112003076 PapC N-terminal domain; Region: PapC_N; pfam13954 291112003077 Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577 291112003078 PapC C-terminal domain; Region: PapC_C; pfam13953 291112003079 HMMPfam hit to PF00577, Fimbrial Usher protein, score 0 291112003080 putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285 291112003081 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 291112003082 Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753 291112003083 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 5.8e-50 291112003084 HMMPfam hit to PF02753, Gram-negative pili assembly chaperone, score 2.2e-08 291112003085 Fimbrial protein; Region: Fimbrial; cl01416 291112003086 HMMPfam hit to PF00419, Fimbrial protein, score 5.7e-10 291112003087 Fimbrial protein; Region: Fimbrial; pfam00419 291112003088 Fimbrial protein; Region: Fimbrial; cl01416 291112003089 1 probable transmembrane helix predicted for PAT1282 by TMHMM2.0 at aa 3-25 291112003090 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112003091 1 probable transmembrane helix predicted for PAT1281 by TMHMM2.0 at aa 7-29 291112003092 HMMPfam hit to PF00419, Fimbrial protein, score 5.8e-24 291112003093 1 probable transmembrane helix predicted for PAT1280 by TMHMM2.0 at aa 5-27 291112003094 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112003095 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112003096 non-specific DNA binding site [nucleotide binding]; other site 291112003097 salt bridge; other site 291112003098 sequence-specific DNA binding site [nucleotide binding]; other site 291112003099 HMMSmart hit to SM00530, no description, score 1.6e-15 291112003100 HMMPfam hit to PF01381, Helix-turn-helix, score 3.9e-16 291112003101 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447 291112003102 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447 291112003103 nudix motif; other site 291112003104 nudix motif; other site 291112003105 HMMPfam hit to PF00293, NUDIX domain, score 0.00012 291112003106 Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788 291112003107 Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108 291112003108 GDP-binding site [chemical binding]; other site 291112003109 ACT binding site; other site 291112003110 IMP binding site; other site 291112003111 HMMPfam hit to PF00709, Adenylosuccinate synthetase, score 1.7e-184 291112003112 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 291112003113 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.6e-06 291112003114 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112003115 active site 291112003116 HisA. Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732 291112003117 Histidine biosynthesis protein; Region: His_biosynth; pfam00977 291112003118 catalytic residues [active] 291112003119 HMMPfam hit to PF00977, Histidine biosynthesis protein, score 1.8e-70 291112003120 Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814 291112003121 threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672 291112003122 11 probable transmembrane helices predicted for PAT1273 by TMHMM2.0 at aa 38-56, 60-82, 112-134, 156-178, 185-207, 222-244, 265-287, 314-336, 357-379, 384-406 and 419-438 291112003123 formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639 291112003124 formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583 291112003125 formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582 291112003126 Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163 291112003127 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.5e-05 291112003128 formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553 291112003129 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752 291112003130 [4Fe-4S] binding site [ion binding]; other site 291112003131 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 291112003132 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 291112003133 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792 291112003134 molybdopterin cofactor binding site; other site 291112003135 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 1.4e-08 291112003136 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 8.2e-29 291112003137 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 do, score 6.9e-19 291112003138 1 probable transmembrane helix predicted for PAT1271 by TMHMM2.0 at aa 40-62 291112003139 Fic family protein [Function unknown]; Region: COG3177 291112003140 Fic/DOC family; Region: Fic; pfam02661 291112003141 HMMPfam hit to PF02661, Fic protein family, score 7.9e-22 291112003142 Uncharacterized protein involved in formation of curli polymers [Cell envelope biogenesis, outer membrane]; Region: CsgG; COG1462 291112003143 HMMPfam hit to PF03783, Curli production assembly/transport componen, score 7e-75 291112003144 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4259 291112003145 Putative bacterial lipoprotein (DUF799); Region: DUF799; cl01813 291112003146 HMMPfam hit to PF05643, Putative bacterial lipoprotein (DUF799), score 3.3e-67 291112003147 Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134 291112003148 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 291112003149 11 probable transmembrane helices predicted for PAT1266 by TMHMM2.0 at aa 12-34, 56-78, 91-113, 128-150, 162-184, 194-216, 248-270, 280-302, 314-336, 346-363 and 384-406 291112003150 HMMPfam hit to PF01554, MatE, score 1.4e-26 291112003151 HMMPfam hit to PF01554, MatE, score 1.1e-31 291112003152 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476 291112003153 ThiF family; Region: ThiF; pfam00899 291112003154 ATP binding site [chemical binding]; other site 291112003155 HMMPfam hit to PF00899, ThiF family, score 8.1e-39 291112003156 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 291112003157 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 291112003158 EamA-like transporter family; Region: EamA; pfam00892 291112003159 10 probable transmembrane helices predicted for PAT1263 by TMHMM2.0 at aa 7-29, 39-57, 64-86, 96-113, 118-137, 142-164, 176-198, 213-235, 242-264 and 268-287 291112003160 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 8.1e-17 291112003161 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 9.5e-17 291112003162 Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317 291112003163 Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460 291112003164 active site 291112003165 Zn binding site [ion binding]; other site 291112003166 HMMPfam hit to PF02074, Carboxypeptidase Taq (M32) metallopepti, score 2.7e-68 291112003167 Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349 291112003168 dimer interface [polypeptide binding]; other site 291112003169 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 291112003170 ligand binding site [chemical binding]; other site 291112003171 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 0.00018 291112003172 hypothetical protein; Provisional; Region: PRK02399 291112003173 Uncharacterized protein family (UPF0261); Region: UPF0261; pfam06792 291112003174 HMMPfam hit to PF06792, Uncharacterised protein family (UPF0261), score 2.4e-220 291112003175 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 291112003176 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112003177 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 4.1e-09 291112003178 Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342 291112003179 catalytic residue [active] 291112003180 Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342 291112003181 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 291112003182 tRNA synthetases class I (K); Region: tRNA-synt_1f; pfam01921 291112003183 active site 291112003184 nucleotide binding site [chemical binding]; other site 291112003185 HIGH motif; other site 291112003186 KMSKS motif; other site 291112003187 HMMPfam hit to PF01921, tRNA synthetases class I (K), score 2.5e-14 291112003188 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012 291112003189 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 291112003190 NAD(P) binding site [chemical binding]; other site 291112003191 catalytic residues [active] 291112003192 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 291112003193 NAD(P) binding site [chemical binding]; other site 291112003194 catalytic residues [active] 291112003195 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112003196 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112003197 putative substrate translocation pore; other site 291112003198 12 probable transmembrane helices predicted for PAT1254 by TMHMM2.0 at aa 13-35, 45-67, 74-96, 106-128, 135-157, 167-186, 199-221, 241-263, 270-289, 293-315, 327-349 and 359-378 291112003199 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.7e-26 291112003200 ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432 291112003201 ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259 291112003202 Walker A/P-loop; other site 291112003203 ATP binding site [chemical binding]; other site 291112003204 Q-loop/lid; other site 291112003205 ABC transporter signature motif; other site 291112003206 Walker B; other site 291112003207 D-loop; other site 291112003208 H-loop/switch region; other site 291112003209 TOBE domain; Region: TOBE_2; pfam08402 291112003210 HMMPfam hit to PF08402, TOBE domain, score 1.5e-08 291112003211 HMMSmart hit to SM00382, no description, score 1.2e-15 291112003212 HMMPfam hit to PF00005, ABC transporter, score 2e-66 291112003213 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 291112003214 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112003215 dimer interface [polypeptide binding]; other site 291112003216 conserved gate region; other site 291112003217 putative PBP binding loops; other site 291112003218 ABC-ATPase subunit interface; other site 291112003219 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112003220 dimer interface [polypeptide binding]; other site 291112003221 conserved gate region; other site 291112003222 putative PBP binding loops; other site 291112003223 ABC-ATPase subunit interface; other site 291112003224 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.4e-08 291112003225 16 probable transmembrane helices predicted for PAT1252 by TMHMM2.0 at aa 17-39, 49-71, 84-106, 110-132, 145-167, 187-218, 231-253, 273-295, 322-344, 381-403, 424-446, 488-510, 522-544, 548-570, 611-633 and 655-677 291112003226 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3e-10 291112003227 Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687 291112003228 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 291112003229 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 3.6e-08 291112003230 regulatory protein UhpC; Provisional; Region: PRK11663 291112003231 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112003232 putative substrate translocation pore; other site 291112003233 12 probable transmembrane helices predicted for PAT1250 by TMHMM2.0 at aa 20-42, 57-76, 83-105, 110-132, 144-166, 170-192, 240-259, 274-296, 308-330, 334-356, 369-388 and 398-420 291112003234 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.5e-48 291112003235 Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851 291112003236 MASE1; Region: MASE1; pfam05231 291112003237 Histidine kinase; Region: HisKA_3; pfam07730 291112003238 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112003239 ATP binding site [chemical binding]; other site 291112003240 Mg2+ binding site [ion binding]; other site 291112003241 G-X-G motif; other site 291112003242 HMMSmart hit to SM00387, no description, score 3.6e-08 291112003243 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 7.8e-17 291112003244 HMMPfam hit to PF07730, Histidine kinase, score 1.9e-13 291112003245 HMMPfam hit to PF05231, MASE1, score 3e-59 291112003246 8 probable transmembrane helices predicted for PAT1249 by TMHMM2.0 at aa 10-32, 53-75, 85-104, 113-135, 139-161, 182-204, 224-243 and 256-278 291112003247 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112003248 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112003249 active site 291112003250 phosphorylation site [posttranslational modification] 291112003251 intermolecular recognition site; other site 291112003252 dimerization interface [polypeptide binding]; other site 291112003253 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112003254 DNA binding residues [nucleotide binding] 291112003255 dimerization interface [polypeptide binding]; other site 291112003256 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 4e-23; HMMSmart hit to SM00421, no description, score 3.6e-19 291112003257 HMMPfam hit to PF08281, Sigma-70, region, score 1.9e-05 291112003258 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.2e-31 291112003259 HMMSmart hit to SM00448, no description, score 5.7e-25 291112003260 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 291112003261 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cd00741 291112003262 nucleophilic elbow; other site 291112003263 catalytic triad; other site 291112003264 beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289 291112003265 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 291112003266 HMMPfam hit to PF00144, Beta-lactamase, score 2.6e-79 291112003267 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 291112003268 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220 291112003269 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 291112003270 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 7.2e-19 291112003271 HMMSmart hit to SM00420, no description, score 1.1e-16 291112003272 HMMPfam hit to PF08279, HTH domain, score 0.00064 291112003273 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 8e-50 291112003274 Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; pfam08013 291112003275 HMMPfam hit to PF08013, Tagatose 6 phosphate kinase, score 0 291112003276 putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815 291112003277 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 291112003278 dimer interface [polypeptide binding]; other site 291112003279 active site 291112003280 AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010 291112003281 putative active site [active] 291112003282 HMMPfam hit to PF01380, SIS domain, score 4.8e-09 291112003283 HMMPfam hit to PF01380, SIS domain, score 0.022 291112003284 PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001 291112003285 active site 291112003286 phosphorylation site [posttranslational modification] 291112003287 HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 4.6e-72 291112003288 PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609 291112003289 HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 1e-93 291112003290 7 probable transmembrane helices predicted for PAT1239 by TMHMM2.0 at aa 2-20, 30-52, 61-83, 93-115, 136-158, 173-195 and 202-233 291112003291 PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613 291112003292 HMMPfam hit to PF03613, PTS system mannose/fructose/sorbose family I, score 9.2e-131 291112003293 4 probable transmembrane helices predicted for PAT1238 by TMHMM2.0 at aa 111-133, 148-170, 191-213 and 257-279 291112003294 PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006 291112003295 active pocket/dimerization site; other site 291112003296 active site 291112003297 phosphorylation site [posttranslational modification] 291112003298 HMMPfam hit to PF03610, PTS system fructose IIA component, score 3.5e-36 291112003299 Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947 291112003300 intersubunit interface [polypeptide binding]; other site 291112003301 active site 291112003302 zinc binding site [ion binding]; other site 291112003303 Na+ binding site [ion binding]; other site 291112003304 HMMPfam hit to PF01116, Fructose-bisphosphate aldolase class-II, score 2.4e-125 291112003305 Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345 291112003306 2 probable transmembrane helices predicted for PAT1233 by TMHMM2.0 at aa 167-189 and 193-214 291112003307 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112003308 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 1.6e-35 291112003309 3 probable transmembrane helices predicted for PAT1232 by TMHMM2.0 at aa 7-29, 49-68 and 80-102 291112003310 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112003311 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 6e-26 291112003312 3 probable transmembrane helices predicted for PAT1230 by TMHMM2.0 at aa 4-26, 38-60 and 70-92 291112003313 2 probable transmembrane helices predicted for PAT1229 by TMHMM2.0 at aa 225-247 and 252-271 291112003314 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112003315 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 3.1e-25 291112003316 3 probable transmembrane helices predicted for PAT1228 by TMHMM2.0 at aa 13-35, 50-72 and 91-113 291112003317 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112003318 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 8.2e-64 291112003319 1 probable transmembrane helix predicted for PAT1226 by TMHMM2.0 at aa 10-32 291112003320 2 probable transmembrane helices predicted for PAT1225 by TMHMM2.0 at aa 205-224 and 229-251 291112003321 2 probable transmembrane helices predicted for PAT1224 by TMHMM2.0 at aa 147-169 and 174-193 291112003322 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112003323 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 2.7e-37 291112003324 3 probable transmembrane helices predicted for PAT1223 by TMHMM2.0 at aa 13-35, 50-72 and 84-103 291112003325 Isochorismatase family; Region: Isochorismatase; pfam00857 291112003326 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 291112003327 catalytic triad [active] 291112003328 conserved cis-peptide bond; other site 291112003329 HMMPfam hit to PF00857, Isochorismatase family, score 4.9e-34 291112003330 S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462 291112003331 HMMPfam hit to PF02675, S-adenosylmethionine decarboxylase, score 9.1e-77 291112003332 spermidine synthase; Provisional; Region: PRK00811 291112003333 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112003334 S-adenosylmethionine binding site [chemical binding]; other site 291112003335 HMMPfam hit to PF01564, Spermine/spermidine synthase, score 2e-118 291112003336 HMMPfam hit to PF08242, Methyltransferase domain, score 0.0017 291112003337 Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898 291112003338 multicopper oxidase; Provisional; Region: PRK10965 291112003339 Multicopper oxidase; Region: Cu-oxidase_3; pfam07732 291112003340 Multicopper oxidase; Region: Cu-oxidase_2; pfam07731 291112003341 HMMPfam hit to PF07732, Multicopper oxidase, score 1.2e-45 291112003342 HMMPfam hit to PF07731, Multicopper oxidase, score 7.2e-19 291112003343 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112003344 active site 291112003345 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 4.1e-36 291112003346 PemK-like protein; Region: PemK; cl00995 291112003347 HMMPfam hit to PF02452, PemK-like protein, score 2.3e-21 291112003348 Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877 291112003349 HMMPfam hit to PF04014, SpoVT / AbrB like domain, score 6.2e-08 291112003350 Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883 291112003351 active site clefts [active] 291112003352 zinc binding site [ion binding]; other site 291112003353 dimer interface [polypeptide binding]; other site 291112003354 HMMPfam hit to PF00484, Carbonic anhydrase, score 7.4e-61 291112003355 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 291112003356 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 291112003357 Walker A/P-loop; other site 291112003358 ATP binding site [chemical binding]; other site 291112003359 Q-loop/lid; other site 291112003360 ABC transporter signature motif; other site 291112003361 Walker B; other site 291112003362 D-loop; other site 291112003363 H-loop/switch region; other site 291112003364 HMMSmart hit to SM00382, no description, score 1.9e-10 291112003365 HMMPfam hit to PF00005, ABC transporter, score 8.6e-52 291112003366 inner membrane transport permease; Provisional; Region: PRK15066 291112003367 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 291112003368 HMMPfam hit to PF01061, ABC-2 type transporter, score 1.6e-47 291112003369 6 probable transmembrane helices predicted for PAT1211 by TMHMM2.0 at aa 20-42, 62-84, 104-126, 141-163, 170-192 and 226-248 291112003370 Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919 291112003371 tetramerization interface [polypeptide binding]; other site 291112003372 active site 291112003373 HMMPfam hit to PF02261, Aspartate decarboxylase, score 9e-79 291112003374 Pantoate-beta-alanine ligase; Region: PanC; cd00560 291112003375 pantoate--beta-alanine ligase; Region: panC; TIGR00018 291112003376 active site 291112003377 ATP-binding site [chemical binding]; other site 291112003378 pantoate-binding site; other site 291112003379 HXXH motif; other site 291112003380 HMMPfam hit to PF02569, Pantoate-beta-alanine ligase, score 2.9e-138 291112003381 Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557 291112003382 oligomerization interface [polypeptide binding]; other site 291112003383 active site 291112003384 metal binding site [ion binding]; metal-binding site 291112003385 HMMPfam hit to PF02548, Ketopantoate hydroxymethyltransferase, score 1e-151 291112003386 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483 291112003387 catalytic center binding site [active] 291112003388 ATP binding site [chemical binding]; other site 291112003389 HMMPfam hit to PF01288, 7,8-dihydro-6-hydroxymethylpterin-pyrophosph, score 3.5e-72 291112003390 poly(A) polymerase I; Provisional; Region: pcnB; PRK11623 291112003391 Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398 291112003392 active site 291112003393 NTP binding site [chemical binding]; other site 291112003394 metal binding triad [ion binding]; metal-binding site 291112003395 Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627 291112003396 Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626 291112003397 HMMPfam hit to PF01743, Poly A polymerase family, score 7.2e-74 291112003398 glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710 291112003399 Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008 291112003400 active site 291112003401 HIGH motif; other site 291112003402 nucleotide binding site [chemical binding]; other site 291112003403 KMSKS motif; other site 291112003404 HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), cata, score 5.3e-25 291112003405 RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778 291112003406 HMMPfam hit to PF01258, Prokaryotic dksA/traR C4-type zinc finge, score 2.4e-34 291112003407 putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347 291112003408 HMMPfam hit to PF03749, Sugar fermentation stimulation protein, score 5.9e-111 291112003409 ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664 291112003410 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112003411 ATP binding site [chemical binding]; other site 291112003412 putative Mg++ binding site [ion binding]; other site 291112003413 helicase superfamily c-terminal domain; Region: HELICc; smart00490 291112003414 nucleotide binding region [chemical binding]; other site 291112003415 ATP-binding site [chemical binding]; other site 291112003416 Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847 291112003417 ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482 291112003418 HMMSmart hit to SM00487, no description, score 6.6e-20 291112003419 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.1e-05 291112003420 HMMSmart hit to SM00490, no description, score 2.8e-15 291112003421 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.5e-13 291112003422 HMMPfam hit to PF04408, Helicase associated domain (HA2), score 2.5e-07 291112003423 HMMPfam hit to PF08482, ATP-dependent helicase C-terminal, score 2.8e-94 291112003424 bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506 291112003425 Transglycosylase; Region: Transgly; pfam00912 291112003426 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 291112003427 1 probable transmembrane helix predicted for PAT1199 by TMHMM2.0 at aa 73-95 291112003428 HMMPfam hit to PF00912, Transglycosylase, score 2.4e-78 291112003429 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 1.9e-20 291112003430 PAAR motif; Region: PAAR_motif; pfam05488 291112003431 S-type Pyocin; Region: Pyocin_S; pfam06958 291112003432 HMMPfam hit to PF05488, PAAR motif, score 1.2e-07 291112003433 HMMPfam hit to PF06958, S-type Pyocin, score 4.3e-34 291112003434 Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379 291112003435 active site clefts [active] 291112003436 zinc binding site [ion binding]; other site 291112003437 dimer interface [polypeptide binding]; other site 291112003438 HMMPfam hit to PF00484, Carbonic anhydrase, score 9.5e-09 291112003439 Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456 291112003440 glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062 291112003441 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 291112003442 inhibitor-cofactor binding pocket; inhibition site 291112003443 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112003444 catalytic residue [active] 291112003445 HMMPfam hit to PF00202, Aminotransferase class-III, score 1.3e-82 291112003446 Protein of unknown function (DUF1460); Region: DUF1460; pfam07313 291112003447 HMMPfam hit to PF07313, Protein of unknown function (DUF1460), score 5.5e-127 291112003448 iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623 291112003449 HMMPfam hit to PF01521, Iron-sulphur cluster biosynthesis, score 3.6e-41 291112003450 vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379 291112003451 Cobalamin binding protein BtuF. These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species. They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144 291112003452 cobalamin binding residues [chemical binding]; other site 291112003453 putative BtuC binding residues; other site 291112003454 dimer interface [polypeptide binding]; other site 291112003455 HMMPfam hit to PF01497, Periplasmic binding protein, score 2.5e-40 291112003456 1 probable transmembrane helix predicted for PAT1187 by TMHMM2.0 at aa 7-27 291112003457 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584 291112003458 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704 291112003459 HMMPfam hit to PF01048, Phosphorylase family, score 1.9e-97 291112003460 deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926 291112003461 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 291112003462 Zn2+ binding site [ion binding]; other site 291112003463 Mg2+ binding site [ion binding]; other site 291112003464 Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286 291112003465 HMMSmart hit to SM00471, no description, score 3.3e-10 291112003466 HMMPfam hit to PF01966, HD domain, score 5.6e-05 291112003467 Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984 291112003468 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 291112003469 dimerization interface [polypeptide binding]; other site 291112003470 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 291112003471 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112003472 dimer interface [polypeptide binding]; other site 291112003473 phosphorylation site [posttranslational modification] 291112003474 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112003475 ATP binding site [chemical binding]; other site 291112003476 Mg2+ binding site [ion binding]; other site 291112003477 G-X-G motif; other site 291112003478 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112003479 Response regulator receiver domain; Region: Response_reg; pfam00072 291112003480 active site 291112003481 phosphorylation site [posttranslational modification] 291112003482 intermolecular recognition site; other site 291112003483 dimerization interface [polypeptide binding]; other site 291112003484 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 291112003485 putative binding surface; other site 291112003486 active site 291112003487 HMMSmart hit to SM00073, no description, score 0.00022 291112003488 HMMPfam hit to PF01627, Hpt domain, score 1.4e-10 291112003489 HMMPfam hit to PF00072, Response regulator receiver domain, score 6.7e-27 291112003490 HMMSmart hit to SM00448, no description, score 1.1e-22 291112003491 HMMSmart hit to SM00387, no description, score 2e-38 291112003492 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 3.7e-41 291112003493 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 5.8e-25; HMMSmart hit to SM00388, no description, score 4.2e-23 291112003494 HMMSmart hit to SM00304, no description, score 4.3e-06 291112003495 HMMPfam hit to PF00672, HAMP domain, score 6.6e-12 291112003496 2 probable transmembrane helices predicted for PAT1184 by TMHMM2.0 at aa 10-32 and 176-198 291112003497 23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168 291112003498 TRAM domain; Region: TRAM; pfam01938 291112003499 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 291112003500 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112003501 S-adenosylmethionine binding site [chemical binding]; other site 291112003502 HMMPfam hit to PF01938, TRAM domain, score 2.3e-11 291112003503 HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 1.8e-10 291112003504 (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872 291112003505 HD domain; Region: HD_4; pfam13328 291112003506 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 291112003507 synthetase active site [active] 291112003508 NTP binding site [chemical binding]; other site 291112003509 metal binding site [ion binding]; metal-binding site 291112003510 TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668 291112003511 ACT domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876 291112003512 HMMPfam hit to PF04607, Region found in RelA / SpoT proteins, score 6.8e-47 291112003513 HMMPfam hit to PF02824, TGS domain, score 7.9e-29 291112003514 HMMPfam hit to PF01842, ACT domain, score 1e-12 291112003515 nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562 291112003516 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528 291112003517 homodimer interface [polypeptide binding]; other site 291112003518 metal binding site [ion binding]; metal-binding site 291112003519 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529 291112003520 homodimer interface [polypeptide binding]; other site 291112003521 active site 291112003522 putative chemical substrate binding site [chemical binding]; other site 291112003523 metal binding site [ion binding]; metal-binding site 291112003524 HMMPfam hit to PF03819, MazG nucleotide pyrophosphohydrolase domain, score 2e-41 291112003525 HMMPfam hit to PF03819, MazG nucleotide pyrophosphohydrolase domain, score 1.1e-05 291112003526 11 probable transmembrane helices predicted for PAT1180 by TMHMM2.0 at aa 31-53, 68-85, 107-129, 144-175, 182-201, 216-235, 242-264, 269-291, 308-330, 334-356 and 363-380 291112003527 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112003528 Walker A/P-loop; other site 291112003529 ATP binding site [chemical binding]; other site 291112003530 Q-loop/lid; other site 291112003531 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112003532 Walker B; other site 291112003533 D-loop; other site 291112003534 H-loop/switch region; other site 291112003535 1 probable transmembrane helix predicted for PAT1175 by TMHMM2.0 at aa 10-32 291112003536 CTP synthetase; Validated; Region: pyrG; PRK05380 291112003537 CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113 291112003538 Catalytic site [active] 291112003539 active site 291112003540 UTP binding site [chemical binding]; other site 291112003541 Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746 291112003542 active site 291112003543 putative oxyanion hole; other site 291112003544 catalytic triad [active] 291112003545 HMMPfam hit to PF06418, CTP synthase N-terminus, score 4e-215 291112003546 1 probable transmembrane helix predicted for PAT1173 by TMHMM2.0 at aa 7-29 291112003547 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.8e-75 291112003548 enolase; Provisional; Region: eno; PRK00077 291112003549 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313 291112003550 dimer interface [polypeptide binding]; other site 291112003551 metal binding site [ion binding]; metal-binding site 291112003552 substrate binding pocket [chemical binding]; other site 291112003553 HMMPfam hit to PF03952, Enolase, N-terminal domain, score 2.6e-70 291112003554 HMMPfam hit to PF00113, Enolase, C-terminal TIM barrel domain, score 6.4e-181 291112003555 Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693 291112003556 PAS fold; Region: PAS_4; pfam08448 291112003557 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112003558 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112003559 DNA binding residues [nucleotide binding] 291112003560 dimerization interface [polypeptide binding]; other site 291112003561 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 1.8e-06; HMMSmart hit to SM00421, no description, score 8.7e-06 291112003562 PAS fold; Region: PAS_4; pfam08448 291112003563 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112003564 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112003565 DNA binding residues [nucleotide binding] 291112003566 dimerization interface [polypeptide binding]; other site 291112003567 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 2.6e-06; HMMSmart hit to SM00421, no description, score 8.7e-06 291112003568 1 probable transmembrane helix predicted for PAT1169 by TMHMM2.0 at aa 33-50 291112003569 Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471 291112003570 Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115 291112003571 transmembrane helices; other site 291112003572 HMMPfam hit to PF00939, Sodium:sulfate symporter transmembrane, score 2.3e-13 291112003573 13 probable transmembrane helices predicted for PAT1168 by TMHMM2.0 at aa 21-40, 55-77, 90-112, 132-165, 177-199, 214-236, 265-287, 292-311, 318-335, 350-372, 379-401, 405-427 and 440-459 291112003574 HMMPfam hit to PF03600, Citrate transporter, score 5.1e-05 291112003575 Archaeal/vacuolar-type H+-ATPase subunit B [Energy production and conversion]; Region: NtpB; COG1156 291112003576 Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637 291112003577 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483 291112003578 active site 291112003579 HMMPfam hit to PF00459, Inositol monophosphatase family, score 4.7e-13 291112003580 radical SAM protein, MSMEG_0568 family; Region: rSAM_MSMEG_0568; TIGR04043 291112003581 Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125 291112003582 Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672 291112003583 TMP-binding site; other site 291112003584 ATP-binding site [chemical binding]; other site 291112003585 HMMPfam hit to PF02223, Thymidylate kinase, score 4.2e-06 291112003586 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 8e-12 291112003587 12 probable transmembrane helices predicted for PAT1161 by TMHMM2.0 at aa 13-35, 39-61, 74-91, 97-119, 132-154, 164-186, 207-229, 239-260, 267-289, 304-326, 339-361 and 366-388 291112003588 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171 291112003589 HMMPfam hit to PF03171, 2OG-Fe(II) oxygenase superfamily, score 0.0011 291112003590 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171 291112003591 HMMPfam hit to PF03171, 2OG-Fe(II) oxygenase superfamily, score 0.008 291112003592 1 probable transmembrane helix predicted for PAT1158 by TMHMM2.0 at aa 5-27 291112003593 membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783 291112003594 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 291112003595 N-acetyl-D-glucosamine binding site [chemical binding]; other site 291112003596 catalytic residue [active] 291112003597 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 291112003598 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 291112003599 HMMSmart hit to SM00257, no description, score 2.9e-06 291112003600 HMMPfam hit to PF01476, LysM domain, score 5.2e-09 291112003601 HMMSmart hit to SM00257, no description, score 7.9e-14 291112003602 HMMPfam hit to PF01476, LysM domain, score 3.1e-16 291112003603 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 3.5e-33 291112003604 HMMPfam hit to PF06474, MLTD_N, score 1e-35 291112003605 hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413 291112003606 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 1.8e-33 291112003607 Methyltransferase domain; Region: Methyltransf_11; pfam08241 291112003608 HMMPfam hit to PF08241, Methyltransferase domain, score 0.00065 291112003609 RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278 291112003610 RNA/DNA hybrid binding site [nucleotide binding]; other site 291112003611 active site 291112003612 HMMPfam hit to PF00075, RNase H, score 4e-62 291112003613 DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406 291112003614 DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131 291112003615 active site 291112003616 catalytic site [active] 291112003617 substrate binding site [chemical binding]; other site 291112003618 HMMSmart hit to SM00479, no description, score 1.9e-49 291112003619 HMMPfam hit to PF00929, Exonuclease, score 4.4e-52 291112003620 Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693 291112003621 Homeodomain-like domain; Region: HTH_23; pfam13384 291112003622 Winged helix-turn helix; Region: HTH_29; pfam13551 291112003623 Winged helix-turn helix; Region: HTH_33; pfam13592 291112003624 DDE superfamily endonuclease; Region: DDE_3; pfam13358 291112003625 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335 291112003626 PAS fold; Region: PAS_4; pfam08448 291112003627 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315 291112003628 DNA binding residues [nucleotide binding] 291112003629 dimerization interface [polypeptide binding]; other site 291112003630 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.5e-05 291112003631 HMMPfam hit to PF08448, PAS fold, score 0.0035 291112003632 PAS fold; Region: PAS_4; pfam08448 291112003633 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112003634 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112003635 DNA binding residues [nucleotide binding] 291112003636 dimerization interface [polypeptide binding]; other site 291112003637 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 4.3e-11; HMMSmart hit to SM00421, no description, score 1.3e-08 291112003638 HMMPfam hit to PF08448, PAS fold, score 1.6e-07 291112003639 PAS fold; Region: PAS_4; pfam08448 291112003640 helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421 291112003641 DNA binding residues [nucleotide binding] 291112003642 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 0.0011 291112003643 HMMPfam hit to PF08448, PAS fold, score 8.5e-16 291112003644 transketolase; Reviewed; Region: PRK12753 291112003645 Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012 291112003646 TPP-binding site [chemical binding]; other site 291112003647 dimer interface [polypeptide binding]; other site 291112003648 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 291112003649 PYR/PP interface [polypeptide binding]; other site 291112003650 dimer interface [polypeptide binding]; other site 291112003651 TPP binding site [chemical binding]; other site 291112003652 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 291112003653 HMMPfam hit to PF00456, Transketolase, thiamine diphosphate b, score 1.3e-243 291112003654 HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 4.4e-67 291112003655 HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 4.3e-10 291112003656 Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234 291112003657 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 9.9e-08 291112003658 1 probable transmembrane helix predicted for PAT1142 by TMHMM2.0 at aa 5-27 291112003659 hypothetical protein; Provisional; Region: PRK05409 291112003660 HMMPfam hit to PF05114, Protein of unknown function (DUF692), score 2.3e-84 291112003661 Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; cl01262 291112003662 Predicted membrane protein [Function unknown]; Region: COG2259 291112003663 4 probable transmembrane helices predicted for PAT1139 by TMHMM2.0 at aa 21-40, 68-90, 97-119 and 162-184 291112003664 HMMPfam hit to PF07681, DoxX, score 1.5e-13 291112003665 cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097 291112003666 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562 291112003667 HMMPfam hit to PF01654, Bacterial Cytochrome Ubiquinol Oxidase, score 7.6e-282 291112003668 9 probable transmembrane helices predicted for PAT1138 by TMHMM2.0 at aa 22-44, 56-78, 98-120, 132-154, 187-209, 221-240, 389-411, 424-446 and 474-496 291112003669 cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219 291112003670 Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322 291112003671 HMMPfam hit to PF02322, Cytochrome oxidase subunit II, score 2.8e-167 291112003672 8 probable transmembrane helices predicted for PAT1137 by TMHMM2.0 at aa 7-24, 77-99, 121-143, 168-190, 203-222, 264-283, 290-312 and 338-360 291112003673 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677 291112003674 InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759 291112003675 HMMPfam hit to PF03811, Insertion element protein, score 4.2e-07 291112003676 erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535 291112003677 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846 291112003678 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 291112003679 HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, NA, score 3.9e-77 291112003680 HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, C-, score 1.1e-68 291112003681 Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318 291112003682 Phosphoglycerate kinase; Region: PGK; pfam00162 291112003683 substrate binding site [chemical binding]; other site 291112003684 hinge regions; other site 291112003685 ADP binding site [chemical binding]; other site 291112003686 catalytic site [active] 291112003687 HMMPfam hit to PF00162, Phosphoglycerate kinase, score 5.8e-137 291112003688 fructose-bisphosphate aldolase; Provisional; Region: PRK09197 291112003689 Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946 291112003690 active site 291112003691 intersubunit interface [polypeptide binding]; other site 291112003692 zinc binding site [ion binding]; other site 291112003693 Na+ binding site [ion binding]; other site 291112003694 HMMPfam hit to PF01116, Fructose-bisphosphate aldolase class-II, score 7.4e-209 291112003695 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 291112003696 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 291112003697 Condensation domain; Region: Condensation; pfam00668 291112003698 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112003699 Nonribosomal peptide synthase; Region: NRPS; pfam08415 291112003700 HMMPfam hit to PF00668, Condensation domain, score 3.8e-17 291112003701 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 3.4e-23 291112003702 Condensation domain; Region: Condensation; pfam00668 291112003703 Nonribosomal peptide synthase; Region: NRPS; pfam08415 291112003704 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114 291112003705 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112003706 acyl-activating enzyme (AAE) consensus motif; other site 291112003707 AMP binding site [chemical binding]; other site 291112003708 HMMPfam hit to PF00668, Condensation domain, score 9.6e-07 291112003709 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 1.7e-12 291112003710 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.9e-104 291112003711 enterobactin synthase subunit F; Provisional; Region: entF; PRK10252 291112003712 HMMPfam hit to PF00668, Condensation domain, score 1.2e-10 291112003713 1 probable transmembrane helix predicted for PAT1126 by TMHMM2.0 at aa 7-29 291112003714 iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957 291112003715 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 291112003716 intersubunit interface [polypeptide binding]; other site 291112003717 1 probable transmembrane helix predicted for PAT1125 by TMHMM2.0 at aa 21-43 291112003718 HMMPfam hit to PF01497, Periplasmic binding protein, score 5.6e-10 291112003719 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 291112003720 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112003721 ABC-ATPase subunit interface; other site 291112003722 dimer interface [polypeptide binding]; other site 291112003723 putative PBP binding regions; other site 291112003724 8 probable transmembrane helices predicted for PAT1124 by TMHMM2.0 at aa 27-49, 78-100, 107-129, 134-156, 163-185, 210-232, 252-274 and 320-342 291112003725 HMMPfam hit to PF01032, FecCD transport family, score 6.6e-104 291112003726 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 291112003727 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112003728 ABC-ATPase subunit interface; other site 291112003729 dimer interface [polypeptide binding]; other site 291112003730 putative PBP binding regions; other site 291112003731 8 probable transmembrane helices predicted for PAT1123 by TMHMM2.0 at aa 26-48, 82-104, 111-133, 143-162, 169-191, 214-236, 264-286 and 326-348 291112003732 HMMPfam hit to PF01032, FecCD transport family, score 1.2e-88 291112003733 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 291112003734 Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244 291112003735 1 probable transmembrane helix predicted for PAT1122 by TMHMM2.0 at aa 23-45 291112003736 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 7.8e-15 291112003737 HMMPfam hit to PF00593, TonB dependent receptor, score 3.1e-27 291112003738 Condensation domain; Region: Condensation; pfam00668 291112003739 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112003740 Condensation domain; Region: Condensation; pfam00668 291112003741 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112003742 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.6e-05 291112003743 HMMPfam hit to PF00668, Condensation domain, score 2.8e-28 291112003744 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 291112003745 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 291112003746 Walker A/P-loop; other site 291112003747 ATP binding site [chemical binding]; other site 291112003748 Q-loop/lid; other site 291112003749 ABC transporter signature motif; other site 291112003750 Walker B; other site 291112003751 D-loop; other site 291112003752 H-loop/switch region; other site 291112003753 HMMSmart hit to SM00382, no description, score 4e-14 291112003754 HMMPfam hit to PF00005, ABC transporter, score 3.1e-53 291112003755 isochorismate synthase EntC; Provisional; Region: PRK15016 291112003756 chorismate binding enzyme; Region: Chorismate_bind; pfam00425 291112003757 HMMPfam hit to PF00425, chorismate binding enzyme, score 1.6e-97 291112003758 enterobactin synthase subunit E; Provisional; Region: entE; PRK10946 291112003759 2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920 291112003760 acyl-activating enzyme (AAE) consensus motif; other site 291112003761 active site 291112003762 AMP binding site [chemical binding]; other site 291112003763 substrate binding site [chemical binding]; other site 291112003764 HMMPfam hit to PF00501, AMP-binding enzyme, score 9.6e-104 291112003765 Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013 291112003766 hydrophobic substrate binding pocket; other site 291112003767 Isochorismatase family; Region: Isochorismatase; pfam00857 291112003768 active site 291112003769 conserved cis-peptide bond; other site 291112003770 Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433 291112003771 HMMPfam hit to PF00857, Isochorismatase family, score 8.2e-90 291112003772 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 7.1e-11 291112003773 2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220 291112003774 2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331 291112003775 putative NAD(P) binding site [chemical binding]; other site 291112003776 active site 291112003777 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.5e-20 291112003778 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 291112003779 3 probable transmembrane helices predicted for PAT1114 by TMHMM2.0 at aa 10-31, 38-60 and 70-92 291112003780 Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534 291112003781 Family description; Region: VCBS; pfam13517 291112003782 Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256 291112003783 Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255 291112003784 HMMPfam hit to PF03534, Salmonella virulence plasmid 65kDa B protein, score 4.1e-165 291112003785 Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538 291112003786 Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006 291112003787 FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385 291112003788 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 291112003789 HMMPfam hit to PF01609, Transposase DDE domain, score 4.5e-38 291112003790 Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538 291112003791 region 13 291112003792 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112003793 Possible hemagglutinin (DUF637); Region: DUF637; pfam04830 291112003794 dipeptide/tripeptide permease B; Provisional; Region: PRK10207 291112003795 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112003796 putative substrate translocation pore; other site 291112003797 14 probable transmembrane helices predicted for PAT1103 by TMHMM2.0 at aa 20-42, 52-74, 83-102, 107-124, 145-167, 171-193, 214-233, 237-254, 267-289, 314-336, 349-371, 386-408, 415-437 and 457-479 291112003798 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.2e-11 291112003799 HMMPfam hit to PF00854, POT family, score 8.4e-101 291112003800 Flavin Reductases; Region: FlaRed; cl00801 291112003801 HMMPfam hit to PF01613, Flavin reductase like domain, score 6.8e-64 291112003802 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310 291112003803 4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241 291112003804 HMMPfam hit to PF03241, 4-hydroxyphenylacetate 3-hydroxylase family, score 3.3e-189 291112003805 1 probable transmembrane helix predicted for PAT1100 by TMHMM2.0 at aa 57-79 291112003806 2 probable transmembrane helices predicted for PAT1099 by TMHMM2.0 at aa 13-35 and 45-67 291112003807 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112003808 3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304 291112003809 active site 291112003810 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 291112003811 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 291112003812 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 3.5e-58 291112003813 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 5.3e-69 291112003814 HMMPfam hit to PF00698, Acyl transferase domain, score 6.8e-23 291112003815 ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953 291112003816 This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822 291112003817 putative NADP binding site [chemical binding]; other site 291112003818 active site 291112003819 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.1e-17 291112003820 3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304 291112003821 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112003822 active site 291112003823 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112003824 active site 291112003825 The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509 291112003826 The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509 291112003827 active site 2 [active] 291112003828 active site 1 [active] 291112003829 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 2.4e-29 291112003830 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 8.4e-46 291112003831 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 3.3e-16 291112003832 HMMPfam hit to PF07977, FabA-like domain, score 6.9e-16 291112003833 2-Nitropropane dioxygenase (NPD)-like domain, associated with the (acyl-carrier-protein) S-malonyltransferase FabD. NPD is part of the nitroalkaneoxidizing enzyme family, that catalyzes oxidative denitrification of nitroalkanes to their corresponding...; Region: NPD_FabD; cd04742 291112003834 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 291112003835 FMN binding site [chemical binding]; other site 291112003836 substrate binding site [chemical binding]; other site 291112003837 putative catalytic residue [active] 291112003838 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 291112003839 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112003840 catalytic residue [active] 291112003841 HMMPfam hit to PF03060, 2-nitropropane dioxygenase, score 5.6e-06 291112003842 HMMPfam hit to PF00202, Aminotransferase class-III, score 2.2e-38 291112003843 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112003844 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 4.8e-46 291112003845 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112003846 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 4.4e-57 291112003847 4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297 291112003848 Cupin domain; Region: Cupin_2; cl17218 291112003849 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112003850 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 6.1e-08 291112003851 HMMSmart hit to SM00342, no description, score 2.7e-22 291112003852 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112003853 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 291112003854 putative substrate translocation pore; other site 291112003855 12 probable transmembrane helices predicted for PAT1087 by TMHMM2.0 at aa 36-58, 73-95, 102-121, 126-148, 161-183, 193-215, 266-288, 303-325, 338-357, 361-383, 396-418 and 428-447 291112003856 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.3e-57 291112003857 HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231 291112003858 HMMPfam hit to PF03328, HpcH/HpaI aldolase/citrate lyase family, score 3.2e-105 291112003859 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312 291112003860 HMMPfam hit to PF01689, Hydratase/decarboxylase, score 9.7e-135 291112003861 succinic semialdehyde dehydrogenase; Region: PLN02278 291112003862 Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103 291112003863 tetramerization interface [polypeptide binding]; other site 291112003864 NAD(P) binding site [chemical binding]; other site 291112003865 catalytic residues [active] 291112003866 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2.1e-236 291112003867 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112003868 bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102 291112003869 putative substrate translocation pore; other site 291112003870 12 probable transmembrane helices predicted for PAT1083 by TMHMM2.0 at aa 12-34, 49-71, 78-100, 104-126, 139-161, 165-187, 219-241, 251-273, 280-302, 307-329, 341-363 and 368-385 291112003871 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.3e-50 291112003872 5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580 291112003873 putative substrate binding pocket [chemical binding]; other site 291112003874 trimer interface [polypeptide binding]; other site 291112003875 HMMPfam hit to PF02962, 5-carboxymethyl-2-hydroxymuconate isomerase, score 1.1e-83 291112003876 The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370 291112003877 Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900 291112003878 putative active site [active] 291112003879 putative metal binding site [ion binding]; other site 291112003880 HMMPfam hit to PF02900, Catalytic LigB subunit of aromatic ring-open, score 1.1e-94 291112003881 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299 291112003882 Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093 291112003883 NAD binding site [chemical binding]; other site 291112003884 catalytic residues [active] 291112003885 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 5.4e-240 291112003886 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303 291112003887 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 291112003888 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 2e-84 291112003889 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 291112003890 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 2.3e-11 291112003891 1 probable transmembrane helix predicted for PAT1077 by TMHMM2.0 at aa 13-35 291112003892 homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337 291112003893 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 291112003894 HMMSmart hit to SM00347, no description, score 2.7e-27 291112003895 HMMPfam hit to PF01047, MarR family, score 6.5e-20 291112003896 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287 291112003897 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112003898 active site 291112003899 DNA binding site [nucleotide binding] 291112003900 Int/Topo IB signature motif; other site 291112003901 HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 1.5e-39 291112003902 CHC2 zinc finger; Region: zf-CHC2; cl17510 291112003903 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112003904 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112003905 active site 291112003906 metal binding site [ion binding]; metal-binding site 291112003907 interdomain interaction site; other site 291112003908 HMMPfam hit to PF01751, TOPRIM, score 1e-05 291112003909 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 1.6e-12 291112003910 HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 1.1e-26 291112003911 HMMPfam hit to PF01381, Helix-turn-helix type 3, score 2.1e-11 291112003912 Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845 291112003913 HMMPfam hit to PF08845, Protein of unknown function DUF1813, HSP20-like, score 1.9e-24 291112003914 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112003915 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 291112003916 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287 291112003917 active site 291112003918 Int/Topo IB signature motif; other site 291112003919 HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 9.3e-36 291112003920 HMMPfam hit to PF02899, Integrase, N-terminal SAM-like, phage, score 9.3e-05 291112003921 HMMPfam hit to PF02899, Integrase, N-terminal SAM-like, phage, score 4.6e-06 291112003922 CHC2 zinc finger; Region: zf-CHC2; cl17510 291112003923 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112003924 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112003925 active site 291112003926 metal binding site [ion binding]; metal-binding site 291112003927 interdomain interaction site; other site 291112003928 HMMPfam hit to PF01751, TOPRIM, score 1.7e-07 291112003929 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 5.5e-13 291112003930 HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 2.7e-27 291112003931 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112003932 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112003933 sequence-specific DNA binding site [nucleotide binding]; other site 291112003934 salt bridge; other site 291112003935 HMMPfam hit to PF01381, Helix-turn-helix type 3, score 2.8e-19 291112003936 Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845 291112003937 HMMPfam hit to PF08845, Protein of unknown function DUF1813, HSP20-like, score 2.9e-25 291112003938 SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; cl01747 291112003939 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112003940 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 291112003941 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287 291112003942 active site 291112003943 Int/Topo IB signature motif; other site 291112003944 HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 9.3e-36 291112003945 HMMPfam hit to PF02899, Integrase, N-terminal SAM-like, phage, score 9.3e-05 291112003946 HMMPfam hit to PF02899, Integrase, N-terminal SAM-like, phage, score 4.6e-06 291112003947 CHC2 zinc finger; Region: zf-CHC2; cl17510 291112003948 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112003949 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112003950 active site 291112003951 metal binding site [ion binding]; metal-binding site 291112003952 interdomain interaction site; other site 291112003953 HMMPfam hit to PF01751, TOPRIM, score 1.7e-07 291112003954 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 5.5e-13 291112003955 HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 2.7e-27 291112003956 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112003957 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112003958 sequence-specific DNA binding site [nucleotide binding]; other site 291112003959 salt bridge; other site 291112003960 HMMPfam hit to PF01381, Helix-turn-helix type 3, score 2.8e-19 291112003961 Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845 291112003962 HMMPfam hit to PF08845, Protein of unknown function DUF1813, HSP20-like, score 2.9e-25 291112003963 SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; cl01747 291112003964 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287 291112003965 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112003966 active site 291112003967 DNA binding site [nucleotide binding] 291112003968 Int/Topo IB signature motif; other site 291112003969 HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 1.5e-39 291112003970 CHC2 zinc finger; Region: zf-CHC2; cl17510 291112003971 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112003972 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112003973 active site 291112003974 metal binding site [ion binding]; metal-binding site 291112003975 interdomain interaction site; other site 291112003976 HMMPfam hit to PF01751, TOPRIM, score 1e-05 291112003977 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 1.6e-12 291112003978 HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 1.1e-26 291112003979 HMMPfam hit to PF01381, Helix-turn-helix type 3, score 2.1e-11 291112003980 Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845 291112003981 HMMPfam hit to PF08845, Protein of unknown function DUF1813, HSP20-like, score 1.9e-24 291112003982 PAAR motif; Region: PAAR_motif; pfam05488 291112003983 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 291112003984 RHS Repeat; Region: RHS_repeat; pfam05593 291112003985 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 291112003986 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 291112003987 RHS Repeat; Region: RHS_repeat; pfam05593 291112003988 RHS Repeat; Region: RHS_repeat; cl11982 291112003989 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 291112003990 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 291112003991 HMMPfam hit to PF05593, RHS Repeat, score 3.1e-05 291112003992 HMMPfam hit to PF05593, RHS Repeat, score 2 291112003993 HMMPfam hit to PF05593, RHS Repeat, score 0.034 291112003994 HMMPfam hit to PF05593, RHS Repeat, score 2.6e-06 291112003995 HMMPfam hit to PF05593, RHS Repeat, score 0.099 291112003996 HMMPfam hit to PF05593, RHS Repeat, score 0.0065 291112003997 HMMPfam hit to PF05593, RHS Repeat, score 0.0032 291112003998 HMMPfam hit to PF05593, RHS Repeat, score 0.0045 291112003999 HMMPfam hit to PF05593, RHS Repeat, score 0.0044 291112004000 HMMPfam hit to PF05593, RHS Repeat, score 7.7e-05 291112004001 HMMPfam hit to PF05593, RHS Repeat, score 0.79 291112004002 HMMPfam hit to PF05593, RHS Repeat, score 0.15 291112004003 HMMPfam hit to PF05488, PAAR motif, score 3.3e-08 291112004004 HMMPfam hit to PF05488, PAAR motif, score 8.4e-07 291112004005 2 probable transmembrane helices predicted for PAT1055 by TMHMM2.0 at aa 45-67 and 74-96 291112004006 HMMPfam hit to PF05488, PAAR motif, score 17 291112004007 Domain of unknown function (DUF1795); Region: DUF1795; pfam08786 291112004008 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112004009 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112004010 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112004011 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 1.9e-53 291112004012 Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977 291112004013 4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648 291112004014 HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 2.8e-10 291112004015 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112004016 HMMPfam hit to PF00419, Fimbrial protein, score 4.4e-05 291112004017 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 291112004018 PapC N-terminal domain; Region: PapC_N; pfam13954 291112004019 Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577 291112004020 PapC C-terminal domain; Region: PapC_C; pfam13953 291112004021 HMMPfam hit to PF00577, Fimbrial Usher protein, score 7e-281 291112004022 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 291112004023 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 291112004024 Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753 291112004025 HMMPfam hit to PF02753, Gram-negative pili assembly chaperone, score 1.2e-14 291112004026 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 8.4e-52 291112004027 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112004028 HMMPfam hit to PF00419, Fimbrial protein, score 1.4e-09 291112004029 1 probable transmembrane helix predicted for PAT4512 by TMHMM2.0 at aa 5-27 291112004030 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 291112004031 5 probable transmembrane helices predicted for PAT4511 by TMHMM2.0 at aa 7-29, 67-89, 109-131, 141-163 and 176-195 291112004032 putative cation:proton antiport protein; Provisional; Region: PRK10669 291112004033 Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651 291112004034 TrkA-N domain; Region: TrkA_N; pfam02254 291112004035 HMMPfam hit to PF02254, TrkA-N domain, score 4.7e-28 291112004036 12 probable transmembrane helices predicted for PAT4509 by TMHMM2.0 at aa 4-23, 30-52, 56-78, 87-109, 114-136, 149-171, 186-208, 229-251, 280-299, 302-324, 339-361 and 368-387 291112004037 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 2.2e-85 291112004038 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112004039 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112004040 putative substrate translocation pore; other site 291112004041 11 probable transmembrane helices predicted for PAT4508 by TMHMM2.0 at aa 21-43, 58-80, 101-123, 149-171, 178-195, 223-245, 266-283, 293-315, 318-340, 350-372 and 379-401 291112004042 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.6e-39 291112004043 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558 291112004044 Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405 291112004045 active site 291112004046 metal binding site [ion binding]; metal-binding site 291112004047 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 291112004048 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 4.1e-21 291112004049 HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 1.6e-44 291112004050 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127 291112004051 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 291112004052 FtsX-like permease family; Region: FtsX; pfam02687 291112004053 HMMPfam hit to PF02687, Predicted permease, score 7.2e-11 291112004054 10 probable transmembrane helices predicted for PAT4506 by TMHMM2.0 at aa 13-35, 240-262, 296-318, 333-355, 376-398, 408-430, 451-473, 682-704, 738-760 and 775-797 291112004055 HMMPfam hit to PF02687, Predicted permease, score 6.6e-16 291112004056 putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584 291112004057 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 291112004058 Walker A/P-loop; other site 291112004059 ATP binding site [chemical binding]; other site 291112004060 Q-loop/lid; other site 291112004061 ABC transporter signature motif; other site 291112004062 Walker B; other site 291112004063 D-loop; other site 291112004064 H-loop/switch region; other site 291112004065 HMMSmart hit to SM00382, no description, score 2.6e-13 291112004066 HMMPfam hit to PF00005, ABC transporter, score 2e-57 291112004067 Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822 291112004068 active site 291112004069 catalytic triad [active] 291112004070 oxyanion hole [active] 291112004071 switch loop; other site 291112004072 1 probable transmembrane helix predicted for PAT4504 by TMHMM2.0 at aa 12-34 291112004073 HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 2e-30 291112004074 oxidoreductase; Provisional; Region: PRK08017 291112004075 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374 291112004076 NADP binding site [chemical binding]; other site 291112004077 active site 291112004078 steroid binding site; other site 291112004079 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.6e-23 291112004080 Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118 291112004081 ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956 291112004082 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429 291112004083 TPR motif; other site 291112004084 binding surface 291112004085 HMMPfam hit to PF00085, Thioredoxin, score 3.8e-12 291112004086 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 291112004087 Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403 291112004088 1 probable transmembrane helix predicted for PAT4501 by TMHMM2.0 at aa 5-24 291112004089 HMMSmart hit to SM00244, no description, score 1.8e-61 291112004090 HMMPfam hit to PF01145, SPFH domain / Band, score 1.9e-82 291112004091 Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585 291112004092 HMMPfam hit to PF01957, Nodulation efficiency protein D (NfeD), score 5.4e-43 291112004093 2 probable transmembrane helices predicted for PAT4500 by TMHMM2.0 at aa 12-34 and 54-76 291112004094 DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227 291112004095 Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108 291112004096 DNA binding residues [nucleotide binding] 291112004097 dimer interface [polypeptide binding]; other site 291112004098 copper binding site [ion binding]; other site 291112004099 HMMSmart hit to SM00422, no description, score 1.1e-26 291112004100 HMMPfam hit to PF00376, MerR family regulatory protein, score 2.2e-13 291112004101 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 291112004102 metal-binding site [ion binding] 291112004103 copper exporting ATPase; Provisional; Region: copA; PRK10671 291112004104 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 291112004105 metal-binding site [ion binding] 291112004106 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 291112004107 metal-binding site [ion binding] 291112004108 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 291112004109 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112004110 motif II; other site 291112004111 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 3.9e-09 291112004112 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 1.1e-07 291112004113 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 7.2e-17 291112004114 8 probable transmembrane helices predicted for PAT4498 by TMHMM2.0 at aa 266-283, 293-315, 332-354, 360-379, 513-535, 540-562, 855-874 and 884-901 291112004115 HMMPfam hit to PF00122, E1-E2 ATPase, score 2e-89 291112004116 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 8.3e-39 291112004117 HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 0.00042 291112004118 Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002 291112004119 Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877 291112004120 TraB family; Region: TraB; cl12050 291112004121 HMMPfam hit to PF07446, GumN protein, score 1.3e-06 291112004122 pyrimidine utilization protein A; Region: RutA; TIGR03612 291112004123 Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094 291112004124 active site 291112004125 dimer interface [polypeptide binding]; other site 291112004126 non-prolyl cis peptide bond; other site 291112004127 insertion regions; other site 291112004128 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 6.6e-06 291112004129 oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890 291112004130 monocarboxylate transporter 1; Region: 2A0113; TIGR00892 291112004131 12 probable transmembrane helices predicted for PAT4494 by TMHMM2.0 at aa 16-38, 53-75, 82-99, 104-126, 139-161, 171-190, 234-256, 269-291, 298-320, 324-346, 353-375 and 385-404 291112004132 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.2e-28 291112004133 Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; cl04114 291112004134 1 probable transmembrane helix predicted for PAT4493 by TMHMM2.0 at aa 20-42 291112004135 riboflavin synthase subunit alpha; Provisional; Region: PRK13020 291112004136 Lumazine binding domain; Region: Lum_binding; pfam00677 291112004137 Lumazine binding domain; Region: Lum_binding; pfam00677 291112004138 HMMPfam hit to PF00677, Lumazine binding domain, score 9.4e-20 291112004139 HMMPfam hit to PF00677, Lumazine binding domain, score 6.2e-19 291112004140 phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019 291112004141 ATP-grasp domain; Region: ATP-grasp; pfam02222 291112004142 HMMPfam hit to PF02222, ATP-grasp domain, score 1.5e-79 291112004143 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041 291112004144 HMMPfam hit to PF00731, AIR carboxylase, score 4.7e-96 291112004145 Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398 291112004146 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 291112004147 putative active site [active] 291112004148 putative metal binding site [ion binding]; other site 291112004149 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 3.7e-14 291112004150 cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920 291112004151 substrate binding site [chemical binding]; other site 291112004152 HMMPfam hit to PF00160, Cyclophilin type peptidyl-prolyl cis-tr, score 8.6e-52 291112004153 cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260 291112004154 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 291112004155 active site 291112004156 HIGH motif; other site 291112004157 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 291112004158 KMSKS motif; other site 291112004159 Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963 291112004160 tRNA binding surface [nucleotide binding]; other site 291112004161 anticodon binding site; other site 291112004162 HMMPfam hit to PF01406, tRNA synthetases class I (C) catalytic d, score 2.5e-215 291112004163 ribosome-associated protein; Provisional; Region: PRK11507 291112004164 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792 291112004165 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763 291112004166 NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080 291112004167 homodimer interface [polypeptide binding]; other site 291112004168 NADP binding site [chemical binding]; other site 291112004169 substrate binding site [chemical binding]; other site 291112004170 HMMPfam hit to PF02882, Tetrahydrofolate dehydrogenase/cyclohyd, score 2.6e-104 291112004171 HMMPfam hit to PF00763, Tetrahydrofolate dehydrogenase/cyclohyd, score 2.1e-70 291112004172 integrase; Provisional; Region: PRK09692 291112004173 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 291112004174 active site 291112004175 Int/Topo IB signature motif; other site 291112004176 HMMPfam hit to PF00589, Phage integrase family, score 8.3e-29 291112004177 Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423 291112004178 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643 291112004179 Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778 291112004180 TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029 291112004181 active site 291112004182 metal binding site [ion binding]; metal-binding site 291112004183 interdomain interaction site; other site 291112004184 AAA domain; Region: AAA_25; pfam13481 291112004185 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 291112004186 Walker A motif; other site 291112004187 ATP binding site [chemical binding]; other site 291112004188 Walker B motif; other site 291112004189 Ash protein family; Region: Phage_ASH; pfam10554 291112004190 1 probable transmembrane helix predicted for PAT4480 by TMHMM2.0 at aa 35-57 291112004191 Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311 291112004192 HMMPfam hit to PF05930, Prophage CP4-57 regulatory protein (AlpA), score 2.7e-27 291112004193 Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834 291112004194 Integrase; Region: Integrase_1; pfam12835 291112004195 integrase; Provisional; Region: PRK09692 291112004196 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 291112004197 active site 291112004198 Int/Topo IB signature motif; other site 291112004199 HMMPfam hit to PF00589, Phage integrase family, score 4.2e-29 291112004200 Protein of unknown function DUF262; Region: DUF262; pfam03235 291112004201 His-Xaa-Ser system protein HsxD; Region: chp_LLNDYxLRE; TIGR03976 291112004202 His-Xaa-Ser system radical SAM maturase HxsB; Region: rSAM_paired_1; TIGR03978 291112004203 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112004204 FeS/SAM binding site; other site 291112004205 HMMPfam hit to PF04055, Radical SAM superfamily, score 7.2e-10 291112004206 His-Xaa-Ser system radical SAM maturase HxsC; Region: rSAM_pair_HxsC; TIGR03977 291112004207 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112004208 FeS/SAM binding site; other site 291112004209 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.2e-12 291112004210 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 291112004211 sporadically distributed protein, TIGR04141 family; Region: TIGR04141 291112004212 Phage Tail Collar Domain; Region: Collar; pfam07484 291112004213 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 8.8e-21 291112004214 Phage Tail Collar Domain; Region: Collar; pfam07484 291112004215 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 1.9e-16 291112004216 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112004217 HMMPfam hit to PF03406, Phage tail fibre repeat, score 1.8e-05 291112004218 Region 1 291112004219 3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428 291112004220 HMMPfam hit to PF01144, Coenzyme A transferase, score 4.6e-56 291112004221 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920 291112004222 HMMPfam hit to PF01144, Coenzyme A transferase, score 9.4e-85 291112004223 psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974 291112004224 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112004225 Walker A motif; other site 291112004226 ATP binding site [chemical binding]; other site 291112004227 Walker B motif; other site 291112004228 arginine finger; other site 291112004229 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 291112004230 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 9.7e-16 291112004231 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.8e-150 291112004232 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00072 291112004233 HMMSmart hit to SM00382, no description, score 2e-16 291112004234 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 291112004235 DNA-binding site [nucleotide binding]; DNA binding site 291112004236 RNA-binding motif; other site 291112004237 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 7e-42 291112004238 HMMSmart hit to SM00357, no description, score 1e-30 291112004239 type III secretion system protein; Reviewed; Region: PRK06937 291112004240 Flagellar assembly protein FliH; Region: FliH; pfam02108 291112004241 YOP proteins translocation protein K (YscK); Region: YscK; pfam06578 291112004242 HMMPfam hit to PF06578, YOP proteins translocation protein K (YscK), score 3.7e-68 291112004243 Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669 291112004244 2 probable transmembrane helices predicted for PAT4454 by TMHMM2.0 at aa 5-27 and 218-240 291112004245 HMMPfam hit to PF01514, Secretory protein of YscJ/FliF family, score 8e-91 291112004246 type III secretion apparatus protein, YscI/HrpB, C-terminal domain; Region: yscI_hrpB_dom; TIGR02497 291112004247 YopR Core; Region: YopR_core; pfam09025 291112004248 type III secretion protein, YscG family; Region: type_III_yscG; TIGR02508 291112004249 Type III secretion needle MxiH like; Region: MxiH; cl09641 291112004250 type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500 291112004251 1 probable transmembrane helix predicted for PAT4449 by TMHMM2.0 at aa 125-144 291112004252 type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516 291112004253 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 291112004254 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 291112004255 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 291112004256 HMMPfam hit to PF00263, Bacterial type II and III secretion system, score 1e-70 291112004257 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 1.1e-11 291112004258 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 1.1e-11 291112004259 type III secretion system chaperone, YscB family; Region: type_III_yscB; TIGR02513 291112004260 HMMPfam hit to PF05932, Tir chaperone protein (CesT), score 1.5e-24 291112004261 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 291112004262 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112004263 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112004264 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.3e-09 291112004265 HMMSmart hit to SM00342, no description, score 1.3e-30 291112004266 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.1e-07 291112004267 ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207 291112004268 active site 291112004269 nucleophile elbow; other site 291112004270 HMMPfam hit to PF01734, Patatin-like phospholipase, score 2.5e-28 291112004271 1 probable transmembrane helix predicted for PAT4441 by TMHMM2.0 at aa 16-38 291112004272 Type III secretory pathway, component EscU [Intracellular trafficking and secretion]; Region: EscU; COG4792 291112004273 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822 291112004274 HMMPfam hit to PF01312, FlhB HrpN YscU SpaS Family, score 1.1e-173 291112004275 4 probable transmembrane helices predicted for PAT4440 by TMHMM2.0 at aa 28-50, 88-110, 136-158 and 183-205 291112004276 Type III secretory pathway, component EscT [Intracellular trafficking and secretion]; Region: EscT; COG4791 291112004277 HMMPfam hit to PF01311, Bacterial export proteins, family, score 1.1e-91 291112004278 6 probable transmembrane helices predicted for PAT4439 by TMHMM2.0 at aa 10-31, 38-57, 77-99, 131-153, 183-205 and 212-234 291112004279 Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794 291112004280 HMMPfam hit to PF01313, Bacterial export proteins, family, score 1.2e-39 291112004281 2 probable transmembrane helices predicted for PAT4438 by TMHMM2.0 at aa 15-37 and 49-71 291112004282 type III secretion system protein YscR; Provisional; Region: PRK12797 291112004283 HMMPfam hit to PF00813, FliP family, score 3.3e-126 291112004284 3 probable transmembrane helices predicted for PAT4437 by TMHMM2.0 at aa 10-40, 53-75 and 155-177 291112004285 type III secretion system protein; Validated; Region: PRK06933 291112004286 Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886 291112004287 HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) prot, score 2.2e-22 291112004288 type III secretion system needle length determinant; Region: type_III_yscP; TIGR02514 291112004289 Type III secretion protein YscO; Region: YscO; pfam07321 291112004290 HMMPfam hit to PF07321, Type III secretion protein YscO, score 2.9e-42 291112004291 type III secretion system ATPase; Provisional; Region: PRK06936 291112004292 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 291112004293 Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136 291112004294 Walker A motif/ATP binding site; other site 291112004295 Walker B motif; other site 291112004296 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 2e-126 291112004297 HMMSmart hit to SM00382, no description, score 4e-07 291112004298 HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 8.1e-12 291112004299 type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568 291112004300 TyeA; Region: TyeA; pfam09059 291112004301 HMMPfam hit to PF07201, Hypersensitivity response secretion protein, score 7.1e-81 291112004302 type III secretion chaperone SycN; Region: type_III_SycN; TIGR02503 291112004303 Type III secretion system YscX (type_III_YscX); Region: Type_III_YscX; pfam09474 291112004304 Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789 291112004305 FHIPEP family; Region: FHIPEP; pfam00771 291112004306 7 probable transmembrane helices predicted for PAT4428 by TMHMM2.0 at aa 19-38, 42-64, 71-93, 108-130, 199-218, 228-250 and 290-312 291112004307 HMMPfam hit to PF00771, FHIPEP family, score 0 291112004308 type III secretion system regulator LcrR; Region: LcrR; TIGR02572 291112004309 type III secretion protein LcrG; Region: LcrG_PcrG; TIGR02573 291112004310 HMMPfam hit to PF07216, LcrG protein, score 9.3e-24 291112004311 V antigen (LcrV) protein; Region: LcrV; pfam04792 291112004312 HMMPfam hit to PF04792, V antigen (LcrV) protein, score 4.1e-138 291112004313 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 291112004314 binding surface 291112004315 TPR repeat; Region: TPR_11; pfam13414 291112004316 TPR motif; other site 291112004317 HMMPfam hit to PF07720, Tetratricopeptide repeat, score 5.6e-07 291112004318 HMMPfam hit to PF07720, Tetratricopeptide repeat, score 1.9 291112004319 Uncharacterized conserved protein [Function unknown]; Region: COG5613 291112004320 HMMPfam hit to PF04888, Secretion system effector C (SseC) like fami, score 2.7e-83 291112004321 2 probable transmembrane helices predicted for PAT4423 by TMHMM2.0 at aa 175-209 and 230-252 291112004322 YopD protein; Region: YopD; pfam05844 291112004323 HMMPfam hit to PF05844, YopD protein, score 7.4e-105 291112004324 1 probable transmembrane helix predicted for PAT4422 by TMHMM2.0 at aa 123-145 291112004325 Tir chaperone protein (CesT) family; Region: CesT; pfam05932 291112004326 HMMPfam hit to PF05932, Tir chaperone protein (CesT), score 5e-29 291112004327 type III secretion system chaperone YscW; Region: YscW; TIGR02567 291112004328 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112004329 Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106 291112004330 HMMPfam hit to PF05106, Phage holin family (Lysis protein S), score 6.4e-44 291112004331 3 probable transmembrane helices predicted for PAT4416 by TMHMM2.0 at aa 15-37, 44-63 and 78-100 291112004332 virion protein; Provisional; Region: V; PHA02564 291112004333 Bacteriophage lysis protein; Region: Phage_lysis; pfam03245 291112004334 HMMPfam hit to PF03245, Bacteriophage lysis protein, score 1.1e-30 291112004335 1 probable transmembrane helix predicted for PAT4414 by TMHMM2.0 at aa 7-24 291112004336 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 291112004337 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 291112004338 active site 291112004339 polysaccharide export protein Wza; Provisional; Region: PRK15078 291112004340 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 291112004341 SLBB domain; Region: SLBB; pfam10531 291112004342 HMMPfam hit to PF02563, Polysaccharide biosynthesis/export protei, score 8.6e-59 291112004343 Low molecular weight phosphatase family; Region: LMWPc; cd00115 291112004344 Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451 291112004345 active site 291112004346 HMMPfam hit to PF01451, Low molecular weight phosphotyrosine protein, score 1.9e-52; HMMSmart hit to SM00226, no description, score 8.6e-54 291112004347 tyrosine kinase; Provisional; Region: PRK11519 291112004348 Chain length determinant protein; Region: Wzz; pfam02706 291112004349 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 291112004350 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 291112004351 HMMPfam hit to PF02706, Chain length determinant protein, score 1.1e-58 291112004352 2 probable transmembrane helices predicted for PAT4410 by TMHMM2.0 at aa 29-51 and 425-447 291112004353 tellurite resistance protein TehB; Provisional; Region: PRK12335 291112004354 Domain of unknown function (DUF1971); Region: DUF1971; pfam09313 291112004355 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112004356 S-adenosylmethionine binding site [chemical binding]; other site 291112004357 HMMPfam hit to PF03848, Tellurite resistance protein TehB, score 4.9e-71 291112004358 HMMPfam hit to PF08241, Methyltransferase domain, score 2.2e-05 291112004359 HMMPfam hit to PF08242, Methyltransferase domain, score 3.9e-07 291112004360 Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069 291112004361 Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782 291112004362 N- and C-terminal domain interface [polypeptide binding]; other site 291112004363 active site 291112004364 MgATP binding site [chemical binding]; other site 291112004365 catalytic site [active] 291112004366 metal binding site [ion binding]; metal-binding site 291112004367 carbohydrate binding site [chemical binding]; other site 291112004368 putative homodimer interface [polypeptide binding]; other site 291112004369 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 7.6e-09 291112004370 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 7.3e-11 291112004371 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 291112004372 amino acid carrier protein; Region: agcS; TIGR00835 291112004373 10 probable transmembrane helices predicted for PAT4407 by TMHMM2.0 at aa 20-42, 91-113, 157-179, 192-214, 221-243, 253-275, 314-336, 362-384, 397-416 and 426-448 291112004374 HMMPfam hit to PF01235, Sodium:alanine symporter family, score 3.8e-151 291112004375 Homeodomain-like domain; Region: HTH_23; cl17451 291112004376 Helix-turn-helix domain; Region: HTH_28; pfam13518 291112004377 putative transposase OrfB; Reviewed; Region: PHA02517 291112004378 HTH-like domain; Region: HTH_21; pfam13276 291112004379 Integrase core domain; Region: rve; pfam00665 291112004380 Integrase core domain; Region: rve_2; pfam13333 291112004381 HMMPfam hit to PF00665, Integrase core domain, score 2.2e-42 291112004382 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 291112004383 Aldehyde dehydrogenase family; Region: Aldedh; pfam00171 291112004384 NAD(P) binding site [chemical binding]; other site 291112004385 catalytic residues [active] 291112004386 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1e-244 291112004387 ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048 291112004388 Periplasmic binding protein TroA_f. These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139 291112004389 putative ligand binding residues [chemical binding]; other site 291112004390 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 291112004391 catalytic loop [active] 291112004392 iron binding site [ion binding]; other site 291112004393 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 1.6e-05 291112004394 probable pectinesterase/pectinesterase inhibitor; Region: PLN02217 291112004395 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE. MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606 291112004396 Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239 291112004397 Divalent cation transporter; Region: MgtE; pfam01769 291112004398 HMMPfam hit to PF00571, CBS domain pair, score 6.2e-09 291112004399 5 probable transmembrane helices predicted for PAT4400 by TMHMM2.0 at aa 191-208, 218-237, 265-287, 292-314 and 327-349 291112004400 HMMPfam hit to PF01769, Divalent cation transporter, score 6.5e-48 291112004401 hypothetical protein; Provisional; Region: PRK04860 291112004402 Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091 291112004403 HMMPfam hit to PF03926, Putative metallopeptidase (SprT family), score 5.4e-71; HMMSmart hit to SM00731, no description, score 6.2e-58 291112004404 S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438 291112004405 S-adenosylmethionine synthetase; Validated; Region: PRK05250 291112004406 S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772 291112004407 S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773 291112004408 HMMPfam hit to PF02773, S-adenosylmethionine synthetase, C-te, score 3.7e-89 291112004409 HMMPfam hit to PF02772, S-adenosylmethionine synthetase, cent, score 2.5e-82 291112004410 HMMPfam hit to PF00438, S-adenosylmethionine synthetase, N-te, score 8.1e-63 291112004411 arginine decarboxylase; Provisional; Region: PRK05354 291112004412 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830 291112004413 dimer interface [polypeptide binding]; other site 291112004414 active site 291112004415 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 291112004416 catalytic residues [active] 291112004417 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261 291112004418 HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, py, score 2.5e-114 291112004419 HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 4.2e-46 291112004420 Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592 291112004421 agmatinase; Region: agmatinase; TIGR01230 291112004422 oligomer interface [polypeptide binding]; other site 291112004423 putative active site [active] 291112004424 Mn binding site [ion binding]; other site 291112004425 HMMPfam hit to PF00491, Arginase family, score 3.1e-117 291112004426 PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812 291112004427 Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861 291112004428 7 probable transmembrane helices predicted for PAT4394 by TMHMM2.0 at aa 15-37, 50-69, 84-101, 122-139, 154-176, 188-207 and 212-229 291112004429 HMMPfam hit to PF03741, Integral membrane protein TerC family, score 1.4e-37 291112004430 MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex. MutH...; Region: MutH_Sau3AI; cd00583 291112004431 putative DNA-binding cleft [nucleotide binding]; other site 291112004432 putative DNA clevage site; other site 291112004433 molecular lever; other site 291112004434 HMMPfam hit to PF02976, DNA mismatch repair enzyme MutH, score 1.6e-51 291112004435 transcriptional regulator SgrR; Provisional; Region: PRK13626 291112004436 Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793 291112004437 The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507 291112004438 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 6.9e-31 291112004439 isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641 291112004440 Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577 291112004441 hypothetical protein; Provisional; Region: PRK14812 291112004442 substrate binding site [chemical binding]; other site 291112004443 HMMPfam hit to PF00694, Aconitase C-terminal domain, score 2.9e-66 291112004444 3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402 291112004445 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583 291112004446 substrate binding site [chemical binding]; other site 291112004447 ligand binding site [chemical binding]; other site 291112004448 HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 1.1e-272 291112004449 3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772 291112004450 tartrate dehydrogenase; Region: TTC; TIGR02089 291112004451 HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 1.6e-217 291112004452 2-isopropylmalate synthase; Validated; Region: PRK00915 291112004453 2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940 291112004454 active site 291112004455 catalytic residues [active] 291112004456 metal binding site [ion binding]; metal-binding site 291112004457 LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502 291112004458 HMMPfam hit to PF08502, LeuA allosteric (dimerisation) domain, score 3.9e-53 291112004459 HMMPfam hit to PF00682, HMGL-like, score 7.5e-148 291112004460 leucine transcriptional activator; Reviewed; Region: leuO; PRK09508 291112004461 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112004462 The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466 291112004463 putative substrate binding pocket [chemical binding]; other site 291112004464 putative dimerization interface [polypeptide binding]; other site 291112004465 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.2e-19 291112004466 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.3e-11 291112004467 Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022 291112004468 Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907 291112004469 acyl-activating enzyme (AAE) consensus motif; other site 291112004470 putative AMP binding site [chemical binding]; other site 291112004471 putative active site [active] 291112004472 putative CoA binding site [chemical binding]; other site 291112004473 HMMPfam hit to PF00501, AMP-binding enzyme, score 9e-80 291112004474 Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545 291112004475 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112004476 HMMPfam hit to PF06821, Alpha/Beta hydrolase family of unknown funct, score 3e-09 291112004477 acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979 291112004478 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 291112004479 PYR/PP interface [polypeptide binding]; other site 291112004480 dimer interface [polypeptide binding]; other site 291112004481 TPP binding site [chemical binding]; other site 291112004482 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 291112004483 Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015 291112004484 TPP-binding site [chemical binding]; other site 291112004485 dimer interface [polypeptide binding]; other site 291112004486 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 3.7e-105 291112004487 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 1.1e-67 291112004488 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 7.9e-73 291112004489 acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895 291112004490 N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878 291112004491 putative valine binding site [chemical binding]; other site 291112004492 dimer interface [polypeptide binding]; other site 291112004493 Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369 291112004494 HMMPfam hit to PF01842, ACT domain, score 2.3e-16 291112004495 DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303 291112004496 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 291112004497 DNA binding site [nucleotide binding] 291112004498 domain linker motif; other site 291112004499 Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274 291112004500 dimerization interface [polypeptide binding]; other site 291112004501 ligand binding site [chemical binding]; other site 291112004502 HMMSmart hit to SM00354, no description, score 7.4e-32 291112004503 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 6.2e-09 291112004504 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 6.7e-07 291112004505 cell division protein MraZ; Reviewed; Region: PRK00326 291112004506 MraZ protein; Region: MraZ; pfam02381 291112004507 MraZ protein; Region: MraZ; pfam02381 291112004508 HMMPfam hit to PF02381, MraZ protein, score 1.5e-27 291112004509 HMMPfam hit to PF02381, MraZ protein, score 5.8e-21 291112004510 16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050 291112004511 MraW methylase family; Region: Methyltransf_5; pfam01795 291112004512 HMMPfam hit to PF01795, MraW methylase family, score 2.6e-174 291112004513 cell division protein FtsL; Provisional; Region: PRK10772 291112004514 HMMPfam hit to PF04999, Cell division protein FtsL, score 5e-47 291112004515 1 probable transmembrane helix predicted for PAT4379 by TMHMM2.0 at aa 20-39 291112004516 peptidoglycan synthase FtsI; Provisional; Region: PRK15105 291112004517 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 291112004518 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 291112004519 1 probable transmembrane helix predicted for PAT4378 by TMHMM2.0 at aa 21-43 291112004520 HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 2.1e-58 291112004521 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 4.7e-113 291112004522 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139 291112004523 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 291112004524 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 291112004525 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 291112004526 HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 7.4e-18 291112004527 HMMPfam hit to PF08245, Mur ligase middle domain, score 4.4e-70 291112004528 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 6.2e-36 291112004529 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773 291112004530 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 291112004531 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 291112004532 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 291112004533 HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 3.2e-21 291112004534 HMMPfam hit to PF08245, Mur ligase middle domain, score 3.2e-63 291112004535 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 1.8e-11 291112004536 phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108 291112004537 Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852 291112004538 Mg++ binding site [ion binding]; other site 291112004539 putative catalytic motif [active] 291112004540 putative substrate binding site [chemical binding]; other site 291112004541 10 probable transmembrane helices predicted for PAT4375 by TMHMM2.0 at aa 20-42, 74-91, 95-114, 134-151, 171-193, 200-219, 234-256, 263-285, 289-311 and 338-357 291112004542 HMMPfam hit to PF00953, Glycosyl transferase family, score 9.9e-86 291112004543 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806 291112004544 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 291112004545 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 291112004546 HMMPfam hit to PF08245, Mur ligase middle domain, score 3e-44 291112004547 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 1.6e-11 291112004548 cell division protein FtsW; Provisional; Region: PRK10774 291112004549 HMMPfam hit to PF01098, Cell cycle protein, score 2.1e-175 291112004550 9 probable transmembrane helices predicted for PAT4373 by TMHMM2.0 at aa 30-49, 69-86, 96-118, 158-177, 181-200, 205-227, 290-312, 324-346 and 356-378 291112004551 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726 291112004552 MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785 291112004553 active site 291112004554 homodimer interface [polypeptide binding]; other site 291112004555 HMMPfam hit to PF03033, Glycosyltransferase family, score 5.7e-53 291112004556 HMMPfam hit to PF04101, Glycosyltransferase family, score 8.4e-53 291112004557 UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421 291112004558 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 291112004559 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 291112004560 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 291112004561 HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 4.8e-46 291112004562 HMMPfam hit to PF08245, Mur ligase middle domain, score 6e-34 291112004563 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 6e-22 291112004564 D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372 291112004565 D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820 291112004566 D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478 291112004567 HMMPfam hit to PF01820, D-ala D-ala ligase N-terminus, score 1.5e-41 291112004568 HMMPfam hit to PF07478, D-ala D-ala ligase C-terminus, score 5.5e-96 291112004569 cell division protein FtsQ; Provisional; Region: PRK10775 291112004570 POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478 291112004571 Cell division protein FtsQ; Region: FtsQ; pfam03799 291112004572 1 probable transmembrane helix predicted for PAT4369 by TMHMM2.0 at aa 25-47 291112004573 HMMPfam hit to PF08478, POTRA domain, FtsQ-type, score 1.3e-27 291112004574 HMMPfam hit to PF03799, Cell division protein FtsQ, score 5.6e-23 291112004575 cell division protein FtsA; Reviewed; Region: ftsA; PRK09472 291112004576 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 291112004577 Cell division protein FtsA; Region: FtsA; pfam14450 291112004578 HMMPfam hit to PF02491, Cell division protein FtsA, score 2.4e-79 291112004579 HMMPfam hit to PF02491, Cell division protein FtsA, score 3.6e-79 291112004580 cell division protein FtsZ; Validated; Region: PRK09330 291112004581 FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201 291112004582 nucleotide binding site [chemical binding]; other site 291112004583 SulA interaction site; other site 291112004584 HMMPfam hit to PF00091, Tubulin/FtsZ family, GTPase domain, score 1.7e-92 291112004585 HMMPfam hit to PF03953, Tubulin/FtsZ family, C-terminal domain, score 3e-44 291112004586 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186 291112004587 UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331 291112004588 HMMPfam hit to PF03331, UDP-3-O-acyl N-acetylglycosamine deacetylase, score 6.2e-188 291112004589 Protein of unknown function (DUF721); Region: DUF721; cl02324 291112004590 SecA regulator SecM; Provisional; Region: PRK02943 291112004591 1 probable transmembrane helix predicted for PAT4364 by TMHMM2.0 at aa 15-37 291112004592 HMMPfam hit to PF06558, Secretion monitor precursor protein (SecM), score 3.5e-27 291112004593 preprotein translocase subunit SecA; Reviewed; Region: PRK12904 291112004594 SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958 291112004595 SEC-C motif; Region: SEC-C; pfam02810 291112004596 HMMPfam hit to PF07517, SecA DEAD-like domain, score 3.2e-214 291112004597 HMMPfam hit to PF01043, SecA preprotein cross-linking domain, score 1.4e-82 291112004598 HMMPfam hit to PF07516, SecA Wing and Scaffold domain, score 9.8e-114 291112004599 HMMPfam hit to PF02810, SEC-C motif, score 2.1e-09 291112004600 The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425 291112004601 active site 291112004602 8-oxo-dGMP binding site [chemical binding]; other site 291112004603 nudix motif; other site 291112004604 metal binding site [ion binding]; metal-binding site 291112004605 HMMPfam hit to PF00293, NUDIX domain, score 1.6e-27 291112004606 DNA gyrase inhibitor; Reviewed; Region: PRK00418 291112004607 HMMPfam hit to PF03884, Domain of unknown function (DUF329), score 8e-36 291112004608 hypothetical protein; Provisional; Region: PRK05287 291112004609 HMMPfam hit to PF07072, Protein of unknown function (DUF1342), score 4.2e-124 291112004610 Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237 291112004611 Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022 291112004612 CoA-binding site [chemical binding]; other site 291112004613 ATP-binding [chemical binding]; other site 291112004614 HMMPfam hit to PF01121, Dephospho-CoA kinase, score 5.2e-99 291112004615 type IV pilin biogenesis protein; Provisional; Region: PRK10573 291112004616 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 291112004617 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 291112004618 3 probable transmembrane helices predicted for PAT4358 by TMHMM2.0 at aa 164-186, 213-235 and 370-392 291112004619 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 1.8e-17 291112004620 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 5.1e-17 291112004621 hypothetical protein; Provisional; Region: PRK10436 291112004622 PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129 291112004623 Walker A motif; other site 291112004624 ATP binding site [chemical binding]; other site 291112004625 Walker B motif; other site 291112004626 HMMPfam hit to PF00437, Type II/IV secretion system protein, score 1.2e-115 291112004627 HMMSmart hit to SM00382, no description, score 0.00067 291112004628 putative major pilin subunit; Provisional; Region: PRK10574 291112004629 1 probable transmembrane helix predicted for PAT4356 by TMHMM2.0 at aa 12-34 291112004630 HMMPfam hit to PF07963, Prokaryotic N-terminal methylation motif, score 3.2e-08 291112004631 quinolinate phosphoribosyltransferase; Validated; Region: PRK09016 291112004632 Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572 291112004633 dimerization interface [polypeptide binding]; other site 291112004634 active site 291112004635 HMMPfam hit to PF01729, Quinolinate phosphoribosyl transferase, C-t, score 8.3e-88 291112004636 HMMPfam hit to PF02749, Quinolinate phosphoribosyl transferase, N-t, score 1e-31 291112004637 regulatory protein AmpE; Provisional; Region: PRK10987 291112004638 4 probable transmembrane helices predicted for PAT4354 by TMHMM2.0 at aa 37-59, 66-88, 146-168 and 266-283 291112004639 Protein of unknown function (DUF2975); Region: DUF2975; pfam11188 291112004640 4 probable transmembrane helices predicted for PAT4353 by TMHMM2.0 at aa 13-35, 82-101, 113-135 and 155-177 291112004641 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112004642 non-specific DNA binding site [nucleotide binding]; other site 291112004643 salt bridge; other site 291112004644 sequence-specific DNA binding site [nucleotide binding]; other site 291112004645 HMMSmart hit to SM00530, no description, score 4.5e-05 291112004646 transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464 291112004647 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 291112004648 DNA-binding site [nucleotide binding]; DNA binding site 291112004649 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 291112004650 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 1.1e-31 291112004651 HMMSmart hit to SM00345, no description, score 5.5e-29 291112004652 HMMPfam hit to PF07729, FCD domain, score 1.6e-35 291112004653 pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405 291112004654 Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017 291112004655 dimer interface [polypeptide binding]; other site 291112004656 TPP-binding site [chemical binding]; other site 291112004657 dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855 291112004658 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 291112004659 E3 interaction surface; other site 291112004660 lipoyl attachment site [posttranslational modification]; other site 291112004661 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 291112004662 E3 interaction surface; other site 291112004663 lipoyl attachment site [posttranslational modification]; other site 291112004664 e3 binding domain; Region: E3_binding; pfam02817 291112004665 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 291112004666 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1.2e-26 291112004667 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 9.3e-24 291112004668 HMMPfam hit to PF02817, e3 binding domain, score 3.7e-18 291112004669 HMMPfam hit to PF00198, 2-oxoacid dehydrogenases acyltransferas, score 1.1e-117 291112004670 dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467 291112004671 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 291112004672 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 291112004673 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 291112004674 HMMPfam hit to PF01134, Glucose inhibited division protein A, score 0.001 291112004675 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 1.4e-72 291112004676 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 2.4e-23 291112004677 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 1.5e-52 291112004678 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238 291112004679 Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576 291112004680 substrate binding site [chemical binding]; other site 291112004681 Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581 291112004682 substrate binding site [chemical binding]; other site 291112004683 ligand binding site [chemical binding]; other site 291112004684 HMMPfam hit to PF06434, Aconitate hydratase, score 6.5e-285 291112004685 HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 1.3e-11 291112004686 Region 2 291112004687 Stress responsive A/B Barrel Domain; Region: Dabb; smart00886 291112004688 HMMPfam hit to PF07876, Stress responsive A/B Barrel Domain, score 1.6e-17 291112004689 hypothetical protein; Provisional; Region: PRK05248 291112004690 HMMPfam hit to PF06062, Uncharacterised protein family (UPF0231), score 4.5e-61 291112004691 mechanosensitive channel MscS; Provisional; Region: PRK10334 291112004692 Mechanosensitive ion channel; Region: MS_channel; pfam00924 291112004693 HMMPfam hit to PF05552, Conserved TM helix, score 1.2e-15 291112004694 3 probable transmembrane helices predicted for PAT4341 by TMHMM2.0 at aa 23-45, 65-87 and 97-119 291112004695 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 1.1e-75 291112004696 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 291112004697 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 3.1e-05 291112004698 anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942 291112004699 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112004700 FeS/SAM binding site; other site 291112004701 radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085 291112004702 HMMPfam hit to PF04055, Radical SAM superfamily, score 3.7e-13 291112004703 arginine exporter protein; Provisional; Region: PRK09304 291112004704 6 probable transmembrane helices predicted for PAT4337 by TMHMM2.0 at aa 4-26, 39-61, 71-93, 113-135, 150-172 and 184-201 291112004705 HMMPfam hit to PF01810, LysE type translocator, score 1.8e-54 291112004706 oxidative stress defense protein; Provisional; Region: PRK11087 291112004707 Uncharacterized conserved protein [Function unknown]; Region: COG2968 291112004708 HMMPfam hit to PF04402, Protein of unknown function (DUF541), score 1.4e-62 291112004709 chromosome replication initiation inhibitor protein; Validated; Region: PRK03635 291112004710 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112004711 The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428 291112004712 putative dimerization interface [polypeptide binding]; other site 291112004713 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-09 291112004714 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.2e-18 291112004715 RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398 291112004716 tetramer (dimer of dimers) interface [polypeptide binding]; other site 291112004717 active site 291112004718 dimer interface [polypeptide binding]; other site 291112004719 HMMPfam hit to PF06026, Ribose 5-phosphate isomerase A (phosph, score 5.4e-101 291112004720 D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790 291112004721 Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176 291112004722 ligand binding site [chemical binding]; other site 291112004723 NAD binding site [chemical binding]; other site 291112004724 tetramer interface [polypeptide binding]; other site 291112004725 catalytic site [active] 291112004726 C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901 291112004727 L-serine binding site [chemical binding]; other site 291112004728 ACT domain interface; other site 291112004729 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 3.7e-36 291112004730 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 1.2e-66 291112004731 HMMPfam hit to PF01842, ACT domain, score 1.7e-10 291112004732 5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812 291112004733 5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360 291112004734 HMMPfam hit to PF01812, 5-formyltetrahydrofolate cyclo-ligase, score 6.7e-61 291112004735 Z-ring-associated protein; Provisional; Region: PRK10972 291112004736 HMMPfam hit to PF05164, Cell division protein ZapA, score 1.5e-31 291112004737 hypothetical protein; Reviewed; Region: PRK01736 291112004738 HMMPfam hit to PF03695, Uncharacterised protein family (UPF0149), score 7.6e-75 291112004739 proline aminopeptidase P II; Provisional; Region: PRK10879 291112004740 Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195 291112004741 Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087 291112004742 active site 291112004743 HMMPfam hit to PF05195, Aminopeptidase P, N-terminal domain, score 3.1e-58 291112004744 HMMPfam hit to PF00557, metallopeptidase family M24, score 3e-107 291112004745 2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732 291112004746 2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984 291112004747 HMMPfam hit to PF01494, FAD binding domain, score 3.4e-07 291112004748 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00026 291112004749 oxidoreductase; Provisional; Region: PRK08013 291112004750 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988 291112004751 HMMPfam hit to PF01494, FAD binding domain, score 1.4e-09 291112004752 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00065 291112004753 glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389 291112004754 Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669 291112004755 HMMPfam hit to PF01571, Glycine cleavage T-protein (aminomethyl tran, score 8.8e-133 291112004756 Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848 291112004757 lipoyl attachment site [posttranslational modification]; other site 291112004758 HMMPfam hit to PF01597, Glycine cleavage H-protein, score 2.7e-68 291112004759 glycine dehydrogenase; Provisional; Region: PRK05367 291112004760 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 291112004761 tetramer interface [polypeptide binding]; other site 291112004762 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112004763 catalytic residue [active] 291112004764 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 291112004765 tetramer interface [polypeptide binding]; other site 291112004766 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112004767 catalytic residue [active] 291112004768 HMMPfam hit to PF02347, Glycine cleavage system P-protein, score 5.3e-267 291112004769 Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831 291112004770 POTRA domain, ShlB-type; Region: POTRA_2; pfam08479 291112004771 Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865 291112004772 HMMPfam hit to PF08479, POTRA domain, ShlB-type, score 1.2e-30 291112004773 HMMPfam hit to PF03865, Haemolysin secretion/activation protein ShlB, score 1.9e-14 291112004774 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112004775 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112004776 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112004777 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112004778 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112004779 Possible hemagglutinin (DUF637); Region: DUF637; pfam04830 291112004780 HMMPfam hit to PF05860, haemagglutination activity domain, score 3.6e-49 291112004781 HMMPfam hit to PF05594, Haemagluttinin repeat, score 0.00028 291112004782 HMMPfam hit to PF05594, Haemagluttinin repeat, score 0.024 291112004783 HMMPfam hit to PF05594, Haemagluttinin repeat, score 3.1 291112004784 HMMPfam hit to PF05594, Haemagluttinin repeat, score 1.8 291112004785 HMMPfam hit to PF05860, haemagglutination activity domain, score 1.6e-42 291112004786 HMMPfam hit to PF05594, Haemagluttinin repeat, score 0.46 291112004787 HMMPfam hit to PF05594, Haemagluttinin repeat, score 3.2 291112004788 HMMPfam hit to PF05594, Haemagluttinin repeat, score 0.22 291112004789 HMMPfam hit to PF05860, haemagglutination activity domain, score 1.8e-35 291112004790 HMMPfam hit to PF05594, Haemagluttinin repeat, score 1.3 291112004791 HMMPfam hit to PF05594, Haemagluttinin repeat, score 1.9 291112004792 HMMPfam hit to PF05594, Haemagluttinin repeat, score 4.1 291112004793 HMMPfam hit to PF05594, Haemagluttinin repeat, score 0.0022 291112004794 HMMPfam hit to PF05594, Haemagluttinin repeat, score 9.8e-05 291112004795 1 probable transmembrane helix predicted for PAT4320 by TMHMM2.0 at aa 37-59 291112004796 Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436 291112004797 gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473 291112004798 Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092 291112004799 tetrameric interface [polypeptide binding]; other site 291112004800 NAD binding site [chemical binding]; other site 291112004801 catalytic residues [active] 291112004802 substrate binding site [chemical binding]; other site 291112004803 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 6.4e-211 291112004804 Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109 291112004805 Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109 291112004806 HMMPfam hit to PF07366, SnoaL-like polyketide cyclase, score 0.00019 291112004807 Transcriptional regulators [Transcription]; Region: FadR; COG2186 291112004808 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 291112004809 DNA-binding site [nucleotide binding]; DNA binding site 291112004810 FCD domain; Region: FCD; pfam07729 291112004811 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 8.6e-15 291112004812 HMMSmart hit to SM00345, no description, score 1.2e-12 291112004813 4-aminobutyrate aminotransferase; Provisional; Region: PRK07495 291112004814 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 291112004815 inhibitor-cofactor binding pocket; inhibition site 291112004816 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112004817 catalytic residue [active] 291112004818 HMMPfam hit to PF00202, Aminotransferase class-III, score 2.2e-145 291112004819 HMMPfam hit to PF00155, Aminotransferase class I and II, score 9.9e-05 291112004820 Protein of unknown function (DUF805); Region: DUF805; pfam05656 291112004821 HMMPfam hit to PF05656, Protein of unknown function (DUF805), score 7.2e-32 291112004822 3 probable transmembrane helices predicted for PAT4307 by TMHMM2.0 at aa 24-46, 51-70 and 83-105 291112004823 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 291112004824 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 291112004825 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2e-73 291112004826 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 291112004827 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 2.5e-38 291112004828 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328 291112004829 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112004830 S-adenosylmethionine binding site [chemical binding]; other site 291112004831 HMMPfam hit to PF05175, Methyltransferase small domain, score 1.7e-06 291112004832 hypothetical protein; Provisional; Region: PRK07505 291112004833 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156 291112004834 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112004835 catalytic residue [active] 291112004836 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.3e-07 291112004837 Chorismate mutase type II; Region: CM_2; smart00830 291112004838 HMMPfam hit to PF01817, Chorismate mutase type II, score 2.9e-25 291112004839 Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743 291112004840 Glutamine amidotransferase class-I; Region: GATase; pfam00117 291112004841 glutamine binding [chemical binding]; other site 291112004842 catalytic triad [active] 291112004843 Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147 291112004844 Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715 291112004845 chorismate binding enzyme; Region: Chorismate_bind; cl10555 291112004846 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 1.2e-67 291112004847 HMMPfam hit to PF04715, Anthranilate synthase component I, N, score 1e-18 291112004848 HMMPfam hit to PF00425, chorismate binding enzyme, score 1.1e-109 291112004849 Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287 291112004850 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 291112004851 prephenate dehydrogenase; Validated; Region: PRK08507 291112004852 methyl viologen resistance protein SmvA; Provisional; Region: PRK14995 291112004853 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112004854 putative substrate translocation pore; other site 291112004855 14 probable transmembrane helices predicted for PAT4299 by TMHMM2.0 at aa 20-42, 57-79, 86-105, 115-137, 144-166, 176-195, 208-225, 235-252, 272-294, 309-331, 336-355, 365-387, 408-430 and 476-498 291112004856 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5e-43 291112004857 1 probable transmembrane helix predicted for PAT4297 by TMHMM2.0 at aa 10-27 291112004858 C-type lectin (CTL)/C-type lectin-like (CTLD) domain; Region: CLECT; cl02432 291112004859 ligand binding surface [chemical binding]; other site 291112004860 2 probable transmembrane helices predicted for PAT4290 by TMHMM2.0 at aa 459-481 and 501-523 291112004861 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 291112004862 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 291112004863 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 291112004864 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 291112004865 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 291112004866 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 291112004867 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 291112004868 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 291112004869 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 7.5e-09 291112004870 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 1.2e-09 291112004871 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 1e-09 291112004872 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.29 291112004873 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.00042 291112004874 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 1.2 291112004875 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 5e-10 291112004876 Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321 291112004877 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112004878 active site 291112004879 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 291112004880 Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826 291112004881 beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 2, complex (x); Region: KR_2_FAS_SDR_x; cd08955 291112004882 KR domain; Region: KR; pfam08659 291112004883 putative NADP binding site [chemical binding]; other site 291112004884 active site 291112004885 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112004886 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 1e-109 291112004887 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 3.2e-79 291112004888 HMMPfam hit to PF00698, Acyl transferase domain, score 2.7e-13 291112004889 HMMPfam hit to PF00106, short chain dehydrogenase, score 7.3e-51 291112004890 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 0.00015 291112004891 1 probable transmembrane helix predicted for PAT4282 by TMHMM2.0 at aa 77-96 291112004892 Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342 291112004893 EamA-like transporter family; Region: EamA; pfam00892 291112004894 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 291112004895 EamA-like transporter family; Region: EamA; pfam00892 291112004896 10 probable transmembrane helices predicted for PAT4280 by TMHMM2.0 at aa 13-35, 45-67, 79-101, 106-128, 137-156, 166-185, 192-214, 229-251, 260-279 and 284-301 291112004897 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 7.5e-28 291112004898 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 6.1e-22 291112004899 HD domain; Region: HD_3; pfam13023 291112004900 putative global regulator; Reviewed; Region: PRK09559 291112004901 folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317 291112004902 HMMPfam hit to PF01571, Glycine cleavage T-protein (aminomethyl tran, score 3.5e-05 291112004903 hypothetical protein; Provisional; Region: PRK10878 291112004904 HMMPfam hit to PF03937, TPR repeat region, score 8.8e-37 291112004905 Protein of unknown function (DUF1434); Region: DUF1434; pfam07254 291112004906 HMMPfam hit to PF07254, Protein of unknown function (DUF1434), score 1.8e-38 291112004907 2 probable transmembrane helices predicted for PAT4276 by TMHMM2.0 at aa 12-34 and 39-57 291112004908 flavodoxin FldB; Provisional; Region: PRK12359 291112004909 HMMPfam hit to PF00258, Flavodoxin, score 7.4e-33 291112004910 site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283 291112004911 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 291112004912 active site 291112004913 Int/Topo IB signature motif; other site 291112004914 HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 2.8e-22 291112004915 HMMPfam hit to PF00589, Phage integrase family, score 3.8e-66 291112004916 protein disulfide isomerase II DsbC; Provisional; Region: PRK10877 291112004917 DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020 291112004918 dimerization domain [polypeptide binding]; other site 291112004919 dimer interface [polypeptide binding]; other site 291112004920 catalytic residues [active] 291112004921 ssDNA exonuclease RecJ; Provisional; Region: PRK11070 291112004922 DHH family; Region: DHH; pfam01368 291112004923 DHHA1 domain; Region: DHHA1; pfam02272 291112004924 HMMPfam hit to PF01368, DHH family, score 1.2e-52 291112004925 HMMPfam hit to PF02272, DHHA1 domain, score 1.4e-13 291112004926 PAAR motif; Region: PAAR_motif; pfam05488 291112004927 S-type Pyocin; Region: Pyocin_S; pfam06958 291112004928 HMMPfam hit to PF05488, PAAR motif, score 2e-08 291112004929 HMMPfam hit to PF06958, S-type Pyocin, score 2.7e-36 291112004930 PAAR motif; Region: PAAR_motif; pfam05488 291112004931 HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085 291112004932 active site 291112004933 HMMPfam hit to PF01844, HNH endonuclease, score 8.1e-09 291112004934 Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320 291112004935 HMMPfam hit to PF01320, Colicin immunity protein / pyocin immu, score 8.3e-46 291112004936 HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085 291112004937 active site 291112004938 HMMSmart hit to SM00507, no description, score 0.00098 291112004939 HMMPfam hit to PF01844, HNH endonuclease, score 6.7e-08 291112004940 Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320 291112004941 HMMPfam hit to PF01320, Colicin immunity protein / pyocin immu, score 7.3e-39 291112004942 Eps15 homology domain; Region: EH; smart00027 291112004943 1 probable transmembrane helix predicted for PAT4261 by TMHMM2.0 at aa 9-31 291112004944 peptide chain release factor 2; Provisional; Region: PRK08787 291112004945 This domain is found in peptide chain release factors; Region: PCRF; smart00937 291112004946 RF-1 domain; Region: RF-1; pfam00472 291112004947 HMMPfam hit to PF03462, PCRF domain, score 1.3e-59 291112004948 HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 4.1e-74 291112004949 lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484 291112004950 LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322 291112004951 dimer interface [polypeptide binding]; other site 291112004952 putative anticodon binding site; other site 291112004953 Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775 291112004954 motif 1; other site 291112004955 active site 291112004956 motif 2; other site 291112004957 motif 3; other site 291112004958 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 4.7e-20 291112004959 HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 2.2e-131 291112004960 Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110 291112004961 Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349 291112004962 trimer interface [polypeptide binding]; other site 291112004963 active site 291112004964 substrate binding site [chemical binding]; other site 291112004965 CoA binding site [chemical binding]; other site 291112004966 HMMPfam hit to PF00132, no description, score 60 291112004967 HMMPfam hit to PF00132, no description, score 0.056 291112004968 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112004969 Radical SAM superfamily; Region: Radical_SAM; pfam04055 291112004970 FeS/SAM binding site; other site 291112004971 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.1e-12 291112004972 Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190 291112004973 active site 291112004974 nucleoside triphosphatase NudI; Provisional; Region: PRK15472 291112004975 HMMPfam hit to PF00293, NUDIX domain, score 3.4e-22 291112004976 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139 291112004977 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 291112004978 conserved cys residue [active] 291112004979 HMMPfam hit to PF01965, DJ-1/PfpI family, score 5.4e-12 291112004980 2 probable transmembrane helices predicted for PAT4253 by TMHMM2.0 at aa 53-75 and 143-165 291112004981 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 291112004982 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 291112004983 conserved cys residue [active] 291112004984 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112004985 HMMPfam hit to PF01965, DJ-1/PfpI family, score 2e-13 291112004986 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 0.00012 291112004987 HMMSmart hit to SM00342, no description, score 1.4e-18 291112004988 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.4e-08 291112004989 propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424 291112004990 Propionate catabolism activator; Region: PrpR_N; pfam06506 291112004991 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112004992 Walker A motif; other site 291112004993 ATP binding site [chemical binding]; other site 291112004994 Walker B motif; other site 291112004995 arginine finger; other site 291112004996 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 291112004997 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 0.0007 291112004998 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.5e-123 291112004999 HMMSmart hit to SM00382, no description, score 1.8e-12 291112005000 HMMPfam hit to PF06506, Propionate catabolism activator, score 1.1e-89 291112005001 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 291112005002 Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714 291112005003 tetramer interface [polypeptide binding]; other site 291112005004 active site 291112005005 Mg2+/Mn2+ binding site [ion binding]; other site 291112005006 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 291112005007 Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117 291112005008 dimer interface [polypeptide binding]; other site 291112005009 active site 291112005010 citrylCoA binding site [chemical binding]; other site 291112005011 oxalacetate/citrate binding site [chemical binding]; other site 291112005012 coenzyme A binding site [chemical binding]; other site 291112005013 catalytic triad [active] 291112005014 HMMPfam hit to PF00285, Citrate synthase, score 2.5e-89 291112005015 2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425 291112005016 2-methylcitrate dehydratase; Region: prpD; TIGR02330 291112005017 HMMPfam hit to PF03972, MmgE/PrpD family, score 9.1e-228 291112005018 propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524 291112005019 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112005020 acyl-activating enzyme (AAE) consensus motif; other site 291112005021 AMP binding site [chemical binding]; other site 291112005022 active site 291112005023 CoA binding site [chemical binding]; other site 291112005024 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.8e-109 291112005025 Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647 291112005026 Protein of unknown function (DUF2946); Region: DUF2946; pfam11162 291112005027 1 probable transmembrane helix predicted for PAT4244 by TMHMM2.0 at aa 15-32 291112005028 TonB-dependent copper receptor; Region: TonB-copper; TIGR01778 291112005029 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 291112005030 N-terminal plug; other site 291112005031 ligand-binding site [chemical binding]; other site 291112005032 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 4.4e-17 291112005033 HMMPfam hit to PF00593, TonB dependent receptor, score 1.4e-27 291112005034 O-acetylhomoserine aminocarboxypropyltransferase; Validated; Region: PRK06084 291112005035 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 291112005036 homodimer interface [polypeptide binding]; other site 291112005037 substrate-cofactor binding pocket; other site 291112005038 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112005039 catalytic residue [active] 291112005040 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 2.3e-211 291112005041 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 0.0001 291112005042 HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase fam, score 0.067 291112005043 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131 291112005044 multidrug efflux protein; Reviewed; Region: PRK01766 291112005045 cation binding site [ion binding]; other site 291112005046 12 probable transmembrane helices predicted for PAT4241 by TMHMM2.0 at aa 13-35, 50-72, 93-115, 125-147, 160-182, 192-214, 238-260, 275-294, 314-336, 349-366, 385-407 and 417-439 291112005047 HMMPfam hit to PF01554, MatE, score 1.4e-31 291112005048 HMMPfam hit to PF01554, MatE, score 5.5e-28 291112005049 Transferrin binding protein-like solute binding protein; Region: Lipoprotein_5; pfam01298 291112005050 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 291112005051 binding surface 291112005052 TPR motif; other site 291112005053 Protein of unknown function (DUF560); Region: DUF560; pfam04575 291112005054 HMMPfam hit to PF04575, Protein of unknown function (DUF560), score 6.8e-07 291112005055 TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715 291112005056 TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786 291112005057 Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244 291112005058 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 2.3e-14 291112005059 HMMPfam hit to PF00593, TonB dependent receptor, score 1.4e-23 291112005060 Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810 291112005061 Gram-negative bacterial tonB protein; Region: TonB; pfam03544 291112005062 1 probable transmembrane helix predicted for PAT4237 by TMHMM2.0 at aa 7-29 291112005063 HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 9e-07 291112005064 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 291112005065 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112005066 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 291112005067 Coenzyme A binding pocket [chemical binding]; other site 291112005068 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2e-08 291112005069 Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240 291112005070 SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053 291112005071 active site 291112005072 oxyanion hole [active] 291112005073 SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053 291112005074 catalytic triad [active] 291112005075 Autotransporter beta-domain; Region: Autotransporter; cl17461 291112005076 HMMPfam hit to PF00657, GDSL-like Lipase/Acylhydrolase, score 2.6e-19 291112005077 HMMPfam hit to PF03797, Autotransporter beta-domain, score 7.1e-30 291112005078 2 probable transmembrane helices predicted for PAT4234 by TMHMM2.0 at aa 30-52 and 74-96 291112005079 FaeA-like protein; Region: FaeA; pfam04703 291112005080 1 probable transmembrane helix predicted for PAT4231 by TMHMM2.0 at aa 7-29 291112005081 Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519 291112005082 1 probable transmembrane helix predicted for PAT4230 by TMHMM2.0 at aa 15-49 291112005083 HMMPfam hit to PF04519, Protein of unknown function, DUF583, score 7.9e-35 291112005084 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 291112005085 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 291112005086 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.1e-13 291112005087 Fic/DOC family; Region: Fic; cl00960 291112005088 HMMPfam hit to PF02661, Fic protein family, score 6.1e-28 291112005089 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 291112005090 Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167 291112005091 putative substrate binding site [chemical binding]; other site 291112005092 putative ATP binding site [chemical binding]; other site 291112005093 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 2.8e-85 291112005094 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 291112005095 PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996 291112005096 active site turn [active] 291112005097 phosphorylation site [posttranslational modification] 291112005098 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 291112005099 HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 9.5e-17 291112005100 10 probable transmembrane helices predicted for PAT4224 by TMHMM2.0 at aa 109-131, 144-166, 176-198, 211-233, 248-270, 283-305, 325-347, 360-382, 392-414 and 427-449 291112005101 HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 4e-60 291112005102 sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322 291112005103 Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996 291112005104 substrate binding [chemical binding]; other site 291112005105 active site 291112005106 Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244 291112005107 HMMSmart hit to SM00640, no description, score 3.2e-134 291112005108 HMMPfam hit to PF00251, Glycosyl hydrolases family 32 N termi, score 3.9e-156 291112005109 HMMPfam hit to PF08244, Glycosyl hydrolases family 32 C termi, score 0.00093 291112005110 Homeodomain-like domain; Region: HTH_23; pfam13384 291112005111 Phage polarity suppression protein (Psu); Region: Psu; pfam07455 291112005112 HMMPfam hit to PF07455, Phage polarity suppression protein (Psu), score 4.1e-23 291112005113 Phage polarity suppression protein (Psu); Region: Psu; pfam07455 291112005114 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 291112005115 Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582 291112005116 active site 291112005117 Int/Topo IB signature motif; other site 291112005118 HMMPfam hit to PF00589, Phage integrase family, score 3.3e-31 291112005119 Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294 291112005120 SmpB-tmRNA interface; other site 291112005121 HMMPfam hit to PF01668, SmpB protein, score 7.3e-39 291112005122 Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813 291112005123 putative coenzyme Q binding site [chemical binding]; other site 291112005124 HMMPfam hit to PF03364, Streptomyces cyclase/dehydrase, score 3.8e-41 291112005125 hypothetical protein; Validated; Region: PRK01777 291112005126 HMMPfam hit to PF03658, Uncharacterised protein family (UPF0125), score 6.6e-52 291112005127 outer membrane biogenesis protein BamE; Provisional; Region: PRK11548 291112005128 SmpA / OmlA family; Region: SmpA_OmlA; pfam04355 291112005129 HMMPfam hit to PF04355, SmpA / OmlA family, score 1.6e-35 291112005130 recombination and repair protein; Provisional; Region: PRK10869 291112005131 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 291112005132 Walker A/P-loop; other site 291112005133 ATP binding site [chemical binding]; other site 291112005134 Q-loop/lid; other site 291112005135 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 291112005136 ABC transporter signature motif; other site 291112005137 Walker B; other site 291112005138 D-loop; other site 291112005139 H-loop/switch region; other site 291112005140 HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 2.3e-11 291112005141 inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378 291112005142 inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231 291112005143 HMMPfam hit to PF01513, ATP-NAD kinase, score 7.2e-99 291112005144 1 probable transmembrane helix predicted for PAT4209 by TMHMM2.0 at aa 138-160 291112005145 Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027 291112005146 ligand binding site [chemical binding]; other site 291112005147 active site 291112005148 UGI interface [polypeptide binding]; other site 291112005149 catalytic site [active] 291112005150 HMMPfam hit to PF03167, Uracil DNA glycosylase superfamily, score 1.1e-82 291112005151 ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204 291112005152 Ankyrin repeats (many copies); Region: Ank_4; pfam13637 291112005153 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 291112005154 HMMPfam hit to PF00023, Ankyrin repeat, score 0.77 291112005155 HMMSmart hit to SM00248, no description, score 5.7 291112005156 HMMPfam hit to PF00023, Ankyrin repeat, score 0.39 291112005157 HMMSmart hit to SM00248, no description, score 1.4 291112005158 HMMPfam hit to PF00023, Ankyrin repeat, score 0.0028 291112005159 HMMSmart hit to SM00248, no description, score 55 291112005160 HMMPfam hit to PF00023, Ankyrin repeat, score 8.4e-08 291112005161 HMMSmart hit to SM00248, no description, score 0.00023 291112005162 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112005163 FeS/SAM binding site; other site 291112005164 Domain of unknown function (DUF4008); Region: DUF4008; pfam13186 291112005165 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.1e-05 291112005166 1 probable transmembrane helix predicted for PAT4203 by TMHMM2.0 at aa 325-347 291112005167 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 291112005168 phosphate binding site [ion binding]; other site 291112005169 HMMPfam hit to PF01884, PcrB family, score 0.00038 291112005170 Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885 291112005171 isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150 291112005172 active site 291112005173 metal binding site [ion binding]; metal-binding site 291112005174 nudix motif; other site 291112005175 HMMPfam hit to PF00293, NUDIX domain, score 2.3e-12 291112005176 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 291112005177 FAD binding domain; Region: FAD_binding_4; pfam01565 291112005178 HMMPfam hit to PF01565, FAD binding domain, score 8.1e-29 291112005179 Rhomboid family; Region: Rhomboid; cl11446 291112005180 6 probable transmembrane helices predicted for PAT4197 by TMHMM2.0 at aa 7-29, 72-89, 96-118, 122-143, 148-170 and 175-192 291112005181 HMMPfam hit to PF01694, Rhomboid family, score 6.8e-08 291112005182 This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799 291112005183 colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427 291112005184 putative ADP-binding pocket [chemical binding]; other site 291112005185 HMMPfam hit to PF00534, Glycosyl transferases group, score 4.5e-39 291112005186 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 291112005187 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 291112005188 active site 291112005189 HMMPfam hit to PF00535, Glycosyl transferase family, score 3.6e-19 291112005190 1 probable transmembrane helix predicted for PAT4194 by TMHMM2.0 at aa 249-271 291112005191 Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535 291112005192 active site 291112005193 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 291112005194 HMMPfam hit to PF00535, Glycosyl transferase family, score 1.7e-17 291112005195 HMMPfam hit to PF01909, Nucleotidyltransferase domain, score 0.0016 291112005196 phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14250 291112005197 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112005198 Walker A/P-loop; other site 291112005199 ATP binding site [chemical binding]; other site 291112005200 Q-loop/lid; other site 291112005201 ABC transporter signature motif; other site 291112005202 Walker B; other site 291112005203 D-loop; other site 291112005204 H-loop/switch region; other site 291112005205 5 probable transmembrane helices predicted for PAT4191 by TMHMM2.0 at aa 19-41, 51-73, 126-148, 152-174 and 257-279 291112005206 HMMSmart hit to SM00382, no description, score 0.00011 291112005207 HMMPfam hit to PF00005, ABC transporter, score 7.9e-21 291112005208 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 291112005209 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112005210 1 probable transmembrane helix predicted for PAT4190 by TMHMM2.0 at aa 20-41 291112005211 5 probable transmembrane helices predicted for PAT4189 by TMHMM2.0 at aa 10-27, 39-56, 60-82, 102-124 and 139-161 291112005212 ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192 291112005213 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 291112005214 ATP binding site [chemical binding]; other site 291112005215 Mg++ binding site [ion binding]; other site 291112005216 motif III; other site 291112005217 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112005218 nucleotide binding region [chemical binding]; other site 291112005219 ATP-binding site [chemical binding]; other site 291112005220 HMMSmart hit to SM00490, no description, score 3.2e-29 291112005221 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.7e-31 291112005222 HMMSmart hit to SM00487, no description, score 1.6e-59 291112005223 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1.5e-68 291112005224 Predicted O-methyltransferase [General function prediction only]; Region: COG4123 291112005225 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112005226 S-adenosylmethionine binding site [chemical binding]; other site 291112005227 HMMPfam hit to PF05175, Methyltransferase small domain, score 2.7e-06 291112005228 L-aspartate oxidase; Provisional; Region: PRK09077 291112005229 L-aspartate oxidase; Provisional; Region: PRK06175 291112005230 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 291112005231 HMMPfam hit to PF02910, Fumarate reductase/succinate dehydroge, score 2e-07 291112005232 HMMPfam hit to PF00890, FAD binding domain, score 2.1e-133 291112005233 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidore, score 0.00019 291112005234 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.00069 291112005235 RNA polymerase sigma factor AlgU; Provisional; Region: algU; PRK11923 291112005236 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 291112005237 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 291112005238 DNA binding residues [nucleotide binding] 291112005239 HMMPfam hit to PF04542, Sigma-70 region, score 6e-20 291112005240 HMMPfam hit to PF08281, Sigma-70, region, score 7.5e-20 291112005241 HMMPfam hit to PF04545, Sigma-70, region, score 3.5e-15 291112005242 anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863 291112005243 Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872 291112005244 Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873 291112005245 HMMPfam hit to PF03872, Anti sigma-E protein RseA, N-terminal domain, score 7.3e-34 291112005246 HMMPfam hit to PF03873, Anti sigma-E protein RseA, C-terminal domain, score 4.1e-14 291112005247 anti-sigma E factor; Provisional; Region: rseB; PRK09455 291112005248 Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026 291112005249 HMMPfam hit to PF03888, MucB/RseB family, score 1.5e-117 291112005250 SoxR reducing system protein RseC; Provisional; Region: PRK10862 291112005251 HMMPfam hit to PF04246, Positive regulator of sigma(E), RseC/MucC, score 9.5e-41 291112005252 2 probable transmembrane helices predicted for PAT4182 by TMHMM2.0 at aa 78-100 and 104-121 291112005253 GTP-binding protein LepA; Provisional; Region: PRK05433 291112005254 LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890 291112005255 G1 box; other site 291112005256 putative GEF interaction site [polypeptide binding]; other site 291112005257 GTP/Mg2+ binding site [chemical binding]; other site 291112005258 Switch I region; other site 291112005259 G2 box; other site 291112005260 G3 box; other site 291112005261 Switch II region; other site 291112005262 G4 box; other site 291112005263 G5 box; other site 291112005264 lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699 291112005265 lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709 291112005266 GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421 291112005267 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 5.4e-74 291112005268 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.7e-08 291112005269 HMMPfam hit to PF00679, Elongation factor G C-terminus, score 1.9e-32 291112005270 HMMPfam hit to PF06421, GTP-binding protein LepA C-terminus, score 1.4e-81 291112005271 signal peptidase I; Provisional; Region: PRK10861 291112005272 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 291112005273 Catalytic site [active] 291112005274 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 291112005275 Catalytic site [active] 291112005276 2 probable transmembrane helices predicted for PAT4180 by TMHMM2.0 at aa 5-22 and 60-82 291112005277 HMMPfam hit to PF00717, Peptidase S24-like, score 1.5e-25 291112005278 ribonuclease III; Reviewed; Region: rnc; PRK00102 291112005279 RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593 291112005280 dimerization interface [polypeptide binding]; other site 291112005281 active site 291112005282 metal binding site [ion binding]; metal-binding site 291112005283 Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048 291112005284 dsRNA binding site [nucleotide binding]; other site 291112005285 HMMSmart hit to SM00535, no description, score 4.1e-57 291112005286 HMMPfam hit to PF00636, RNase3 domain, score 2e-48 291112005287 HMMSmart hit to SM00358, no description, score 4.4e-22 291112005288 HMMPfam hit to PF00035, Double-stranded RNA binding motif, score 4.3e-17 291112005289 GTPase Era; Reviewed; Region: era; PRK00089 291112005290 E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163 291112005291 G1 box; other site 291112005292 GTP/Mg2+ binding site [chemical binding]; other site 291112005293 Switch I region; other site 291112005294 G2 box; other site 291112005295 Switch II region; other site 291112005296 G3 box; other site 291112005297 G4 box; other site 291112005298 G5 box; other site 291112005299 KH domain; Region: KH_2; pfam07650 291112005300 HMMPfam hit to PF01926, GTPase of unknown function, score 1.3e-39 291112005301 HMMPfam hit to PF07650, KH domain, score 2.1e-25 291112005302 DNA repair protein RecO; Reviewed; Region: recO; PRK00085 291112005303 Recombination protein O N terminal; Region: RecO_N; pfam11967 291112005304 Recombination protein O C terminal; Region: RecO_C; pfam02565 291112005305 HMMPfam hit to PF02565, Recombination protein O, score 3.1e-91 291112005306 Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003 291112005307 active site 291112005308 hydrophilic channel; other site 291112005309 dimerization interface [polypeptide binding]; other site 291112005310 catalytic residues [active] 291112005311 active site lid [active] 291112005312 HMMPfam hit to PF03740, Pyridoxal phosphate biosynthesis protein Pdx, score 5.4e-147 291112005313 4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070 291112005314 HMMPfam hit to PF01648, 4'-phosphopantetheinyl transferase superfami, score 1.3e-23 291112005315 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 291112005316 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 8e-05 291112005317 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112005318 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 1.1e-28 291112005319 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112005320 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112005321 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 5.9e-31 291112005322 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112005323 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 2.6e-29 291112005324 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112005325 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112005326 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112005327 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 291112005328 nucleoside/Zn binding site; other site 291112005329 dimer interface [polypeptide binding]; other site 291112005330 catalytic motif [active] 291112005331 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 2.4e-40 291112005332 arginine decarboxylase; Provisional; Region: PRK15029 291112005333 Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709 291112005334 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 291112005335 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112005336 catalytic residue [active] 291112005337 Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711 291112005338 HMMPfam hit to PF03711, Orn/Lys/Arg decarboxylase, C-terminal doma, score 4.1e-64 291112005339 HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major domain, score 2.2e-204 291112005340 HMMPfam hit to PF03709, Orn/Lys/Arg decarboxylase, N-terminal doma, score 6.1e-33 291112005341 membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859 291112005342 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112005343 substrate binding pocket [chemical binding]; other site 291112005344 membrane-bound complex binding site; other site 291112005345 hinge residues; other site 291112005346 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 291112005347 N-acetyl-D-glucosamine binding site [chemical binding]; other site 291112005348 catalytic residue [active] 291112005349 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 3.6e-42 291112005350 HMMSmart hit to SM00062, no description, score 2.4e-39 291112005351 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 2.6e-23 291112005352 phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297 291112005353 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203 291112005354 dimerization interface [polypeptide binding]; other site 291112005355 ATP binding site [chemical binding]; other site 291112005356 AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019 291112005357 dimerization interface [polypeptide binding]; other site 291112005358 ATP binding site [chemical binding]; other site 291112005359 Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740 291112005360 putative active site [active] 291112005361 catalytic triad [active] 291112005362 HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 2.2e-42 291112005363 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 8.6e-38 291112005364 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 1.9e-23 291112005365 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 291112005366 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112005367 dimer interface [polypeptide binding]; other site 291112005368 phosphorylation site [posttranslational modification] 291112005369 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112005370 ATP binding site [chemical binding]; other site 291112005371 Mg2+ binding site [ion binding]; other site 291112005372 G-X-G motif; other site 291112005373 2 probable transmembrane helices predicted for PAT4158 by TMHMM2.0 at aa 29-46 and 190-212 291112005374 HMMPfam hit to PF00672, HAMP domain, score 3.5e-09 291112005375 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.7e-18; HMMSmart hit to SM00388, no description, score 9.9e-17 291112005376 HMMSmart hit to SM00387, no description, score 6.2e-25 291112005377 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.4e-26 291112005378 hypothetical protein; Provisional; Region: PRK10722 291112005379 response regulator GlrR; Provisional; Region: PRK15115 291112005380 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112005381 active site 291112005382 phosphorylation site [posttranslational modification] 291112005383 intermolecular recognition site; other site 291112005384 dimerization interface [polypeptide binding]; other site 291112005385 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112005386 Walker A motif; other site 291112005387 ATP binding site [chemical binding]; other site 291112005388 Walker B motif; other site 291112005389 arginine finger; other site 291112005390 HMMPfam hit to PF00072, Response regulator receiver domain, score 6.2e-43 291112005391 HMMSmart hit to SM00448, no description, score 1.7e-33 291112005392 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 3.2e-148 291112005393 HMMSmart hit to SM00382, no description, score 1.7e-10 291112005394 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00078 291112005395 NAD synthetase; Provisional; Region: PRK13981 291112005396 Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570 291112005397 multimer interface [polypeptide binding]; other site 291112005398 active site 291112005399 catalytic triad [active] 291112005400 protein interface 1 [polypeptide binding]; other site 291112005401 NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553 291112005402 homodimer interface [polypeptide binding]; other site 291112005403 NAD binding pocket [chemical binding]; other site 291112005404 ATP binding pocket [chemical binding]; other site 291112005405 Mg binding site [ion binding]; other site 291112005406 active-site loop [active] 291112005407 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 4.7e-15 291112005408 HMMPfam hit to PF02540, NAD synthase, score 2.3e-102 291112005409 nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858 291112005410 Nitrogen regulatory protein P-II; Region: P-II; smart00938 291112005411 HMMPfam hit to PF00543, Nitrogen regulatory protein P-II, score 1.5e-70 291112005412 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112005413 acyl-activating enzyme (AAE) consensus motif; other site 291112005414 active site 291112005415 AMP binding site [chemical binding]; other site 291112005416 CoA binding site [chemical binding]; other site 291112005417 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 291112005418 NAD(P) binding site [chemical binding]; other site 291112005419 catalytic residues [active] 291112005420 Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751 291112005421 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 291112005422 1 probable transmembrane helix predicted for PAT4150 by TMHMM2.0 at aa 52-74 291112005423 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 291112005424 Condensation domain; Region: Condensation; pfam00668 291112005425 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112005426 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112005427 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114 291112005428 acyl-activating enzyme (AAE) consensus motif; other site 291112005429 AMP binding site [chemical binding]; other site 291112005430 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 6.7e-06 291112005431 HMMPfam hit to PF00501, AMP-binding enzyme, score 6.2e-108 291112005432 HMMPfam hit to PF00668, Condensation domain, score 2.9e-29 291112005433 Condensation domain; Region: Condensation; pfam00668 291112005434 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112005435 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112005436 acyl-activating enzyme (AAE) consensus motif; other site 291112005437 AMP binding site [chemical binding]; other site 291112005438 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 291112005439 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 3.6e-09 291112005440 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.2e-86 291112005441 HMMPfam hit to PF00668, Condensation domain, score 9.5e-11 291112005442 RTX toxin acyltransferase family; Region: HlyC; cl01131 291112005443 Uncharacterized ACR, YdiU/UPF0061 family; Region: UPF0061; pfam02696 291112005444 1 probable transmembrane helix predicted for PAT4142 by TMHMM2.0 at aa 31-53 291112005445 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 291112005446 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112005447 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112005448 1 probable transmembrane helix predicted for PAT4141 by TMHMM2.0 at aa 21-43 291112005449 HMMPfam hit to PF00529, HlyD family secretion protein, score 0.001 291112005450 A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419 291112005451 putative active site [active] 291112005452 HMMPfam hit to PF03412, Peptidase C39 family, score 2.1e-19 291112005453 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 291112005454 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112005455 ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246 291112005456 Walker A/P-loop; other site 291112005457 ATP binding site [chemical binding]; other site 291112005458 Q-loop/lid; other site 291112005459 ABC transporter signature motif; other site 291112005460 Walker B; other site 291112005461 D-loop; other site 291112005462 H-loop/switch region; other site 291112005463 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 2.1e-43 291112005464 5 probable transmembrane helices predicted for PAT4139 by TMHMM2.0 at aa 20-42, 52-74, 132-151, 155-172 and 242-264 291112005465 HMMSmart hit to SM00382, no description, score 9.7e-18 291112005466 HMMPfam hit to PF00005, ABC transporter, score 2.3e-53 291112005467 1 probable transmembrane helix predicted for PAT4138 by TMHMM2.0 at aa 15-36 291112005468 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112005469 PAAR motif; Region: PAAR_motif; pfam05488 291112005470 bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289 291112005471 Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040 291112005472 heme-binding site [chemical binding]; other site 291112005473 FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184 291112005474 FAD binding pocket [chemical binding]; other site 291112005475 FAD binding motif [chemical binding]; other site 291112005476 phosphate binding motif [ion binding]; other site 291112005477 beta-alpha-beta structure motif; other site 291112005478 NAD binding pocket [chemical binding]; other site 291112005479 Heme binding pocket [chemical binding]; other site 291112005480 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 5.9e-18 291112005481 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 6.9e-13 291112005482 HMMPfam hit to PF00042, Globin, score 1.1e-24 291112005483 serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011 291112005484 Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378 291112005485 dimer interface [polypeptide binding]; other site 291112005486 active site 291112005487 glycine-pyridoxal phosphate binding site [chemical binding]; other site 291112005488 folate binding site [chemical binding]; other site 291112005489 HMMPfam hit to PF00464, Serine hydroxymethyltransferase, score 4e-282 291112005490 HMMPfam hit to PF01276, Orn/Lys/Arg decarboxylase, major doma, score 0.022 291112005491 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.00098 291112005492 putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128 291112005493 HMMPfam hit to PF01306, LacY proton/sugar symporter, score 1.6e-06 291112005494 12 probable transmembrane helices predicted for PAT4129 by TMHMM2.0 at aa 9-31, 41-60, 67-89, 93-111, 132-154, 158-180, 208-230, 235-257, 270-289, 294-316, 329-351 and 356-373 291112005495 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.5e-14 291112005496 trehalose repressor; Provisional; Region: treR; PRK09492 291112005497 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 291112005498 DNA binding site [nucleotide binding] 291112005499 domain linker motif; other site 291112005500 Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542 291112005501 dimerization interface [polypeptide binding]; other site 291112005502 ligand binding site [chemical binding]; other site 291112005503 HMMSmart hit to SM00354, no description, score 3.4e-28 291112005504 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 7.1e-13 291112005505 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.6e-05 291112005506 PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007 291112005507 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 291112005508 active site turn [active] 291112005509 phosphorylation site [posttranslational modification] 291112005510 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 291112005511 HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 2e-09 291112005512 10 probable transmembrane helices predicted for PAT4127 by TMHMM2.0 at aa 113-135, 161-183, 190-212, 232-251, 263-285, 305-327, 347-369, 379-401, 408-430 and 445-467 291112005513 HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 1.5e-33 291112005514 trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933 291112005515 Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333 291112005516 Ca binding site [ion binding]; other site 291112005517 active site 291112005518 catalytic site [active] 291112005519 HMMPfam hit to PF00128, Alpha amylase, catalytic domain, score 6e-141; HMMSmart hit to SM00642, no description, score 7.7e-154 291112005520 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483 291112005521 IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639 291112005522 active site 291112005523 dimerization interface [polypeptide binding]; other site 291112005524 HMMPfam hit to PF00459, Inositol monophosphatase family, score 3.1e-103 291112005525 tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114 291112005526 SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307 291112005527 HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 3.1e-37 291112005528 DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857 291112005529 Rrf2 family protein; Region: rrf2_super; TIGR00738 291112005530 HMMPfam hit to PF02082, Transcriptional regulator, score 1.3e-50 291112005531 cysteine desulfurase; Provisional; Region: PRK14012 291112005532 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 291112005533 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112005534 catalytic residue [active] 291112005535 HMMPfam hit to PF00266, Aminotransferase class-V, score 2.2e-123 291112005536 HMMPfam hit to PF01212, Beta-eliminating lyase, score 2.8e-05 291112005537 NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822 291112005538 Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664 291112005539 trimerization site [polypeptide binding]; other site 291112005540 active site 291112005541 HMMPfam hit to PF01592, NifU-like N terminal domain, score 5.4e-81 291112005542 iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502 291112005543 HMMPfam hit to PF01521, Iron-sulphur cluster biosynthesis, score 1.5e-41 291112005544 co-chaperone HscB; Provisional; Region: hscB; PRK05014 291112005545 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 291112005546 HSP70 interaction site [polypeptide binding]; other site 291112005547 HMMSmart hit to SM00271, no description, score 5.3e-09 291112005548 HMMPfam hit to PF00226, DnaJ domain, score 9.7e-10 291112005549 HMMPfam hit to PF07743, HSCB C-terminal oligomerisation domain, score 2.1e-33 291112005550 chaperone protein HscA; Provisional; Region: hscA; PRK05183 291112005551 Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236 291112005552 nucleotide binding site [chemical binding]; other site 291112005553 putative NEF/HSP70 interaction site [polypeptide binding]; other site 291112005554 SBD interface [polypeptide binding]; other site 291112005555 HMMPfam hit to PF00012, Hsp70 protein, score 4.3e-260 291112005556 Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633 291112005557 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 291112005558 catalytic loop [active] 291112005559 iron binding site [ion binding]; other site 291112005560 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 1.6e-24 291112005561 hypothetical protein; Provisional; Region: PRK10721 291112005562 HMMPfam hit to PF04384, Protein of unknown function (DUF528), score 6.8e-42 291112005563 aminopeptidase B; Provisional; Region: PRK05015 291112005564 Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433 291112005565 interface (dimer of trimers) [polypeptide binding]; other site 291112005566 Substrate-binding/catalytic site; other site 291112005567 Zn-binding sites [ion binding]; other site 291112005568 HMMPfam hit to PF00883, Cytosol aminopeptidase family, catalyti, score 2.8e-156 291112005569 SseB protein; Region: SseB; cl06279 291112005570 HMMPfam hit to PF07179, SseB protein, score 2.9e-14 291112005571 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 291112005572 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 291112005573 dimer interface [polypeptide binding]; other site 291112005574 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112005575 catalytic residue [active] 291112005576 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 3.5e-82 291112005577 FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454 291112005578 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529 291112005579 Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670 291112005580 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 291112005581 6 probable transmembrane helices predicted for PAT4109 by TMHMM2.0 at aa 6-28, 45-67, 71-89, 116-138, 148-170 and 183-205 291112005582 HMMPfam hit to PF01810, LysE type translocator, score 2.3e-14 291112005583 1 probable transmembrane helix predicted for PAT4107 by TMHMM2.0 at aa 15-37 291112005584 Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237 291112005585 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 2.1e-11 291112005586 Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373 291112005587 MG2 domain; Region: A2M_N; pfam01835 291112005588 Proteins similar to alpha2-macroglobulin (alpha (2)-M). Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor. The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891 291112005589 surface patch; other site 291112005590 thioester region; other site 291112005591 specificity defining residues; other site 291112005592 HMMPfam hit to PF01835, Alpha-2-macroglobulin family N-terminal regi, score 1.4e-84 291112005593 HMMPfam hit to PF07703, Alpha-2-macroglobulin family N-terminal regi, score 2.3e-36 291112005594 penicillin-binding protein 1C; Provisional; Region: PRK11240 291112005595 Transglycosylase; Region: Transgly; pfam00912 291112005596 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 291112005597 Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832 291112005598 1 probable transmembrane helix predicted for PAT4103 by TMHMM2.0 at aa 7-24 291112005599 HMMPfam hit to PF00912, Transglycosylase, score 9.7e-81 291112005600 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 1.8e-12 291112005601 HMMPfam hit to PF06832, Penicillin-Binding Protein C-terminus, score 7.3e-16 291112005602 Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413 291112005603 active site 291112005604 multimer interface [polypeptide binding]; other site 291112005605 HMMSmart hit to SM00562, no description, score 2.3e-88 291112005606 HMMPfam hit to PF00334, Nucleoside diphosphate kinase, score 7.1e-91 291112005607 ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194 291112005608 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112005609 FeS/SAM binding site; other site 291112005610 HMMPfam hit to PF04055, Radical SAM superfamily, score 2.7e-17 291112005611 TPR repeat; Region: TPR_11; pfam13414 291112005612 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 291112005613 binding surface 291112005614 TPR motif; other site 291112005615 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 8.1e-05; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 6.9e-05; HMMSmart hit to SM00028, no description, score 0.0056 291112005616 HMMSmart hit to SM00028, no description, score 89 291112005617 cytoskeletal protein RodZ; Provisional; Region: PRK10856 291112005618 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112005619 non-specific DNA binding site [nucleotide binding]; other site 291112005620 salt bridge; other site 291112005621 sequence-specific DNA binding site [nucleotide binding]; other site 291112005622 Domain of unknown function (DUF4115); Region: DUF4115; pfam13464 291112005623 HMMSmart hit to SM00530, no description, score 0.0037 291112005624 1 probable transmembrane helix predicted for PAT4099 by TMHMM2.0 at aa 111-133 291112005625 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366 291112005626 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694 291112005627 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694 291112005628 HMMPfam hit to PF04551, GcpE protein, score 3e-244 291112005629 histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037 291112005630 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773 291112005631 dimer interface [polypeptide binding]; other site 291112005632 motif 1; other site 291112005633 active site 291112005634 motif 2; other site 291112005635 motif 3; other site 291112005636 HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859 291112005637 anticodon binding site; other site 291112005638 HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 8.6e-59 291112005639 HMMPfam hit to PF03129, Anticodon binding domain, score 8.6e-15 291112005640 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976 291112005641 Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976 291112005642 1 probable transmembrane helix predicted for PAT4096 by TMHMM2.0 at aa 17-39 291112005643 outer membrane biogenesis protein BamB; Provisional; Region: PRK11138 291112005644 Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276 291112005645 Trp docking motif [polypeptide binding]; other site 291112005646 HMMSmart hit to SM00564, no description, score 4.6e-05 291112005647 HMMSmart hit to SM00564, no description, score 0.026 291112005648 HMMSmart hit to SM00564, no description, score 0.0003 291112005649 HMMSmart hit to SM00564, no description, score 85 291112005650 HMMSmart hit to SM00564, no description, score 0.00049 291112005651 HMMSmart hit to SM00564, no description, score 2.1e+02 291112005652 HMMSmart hit to SM00564, no description, score 2 291112005653 GTP-binding protein Der; Reviewed; Region: PRK00093 291112005654 EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894 291112005655 G1 box; other site 291112005656 GTP/Mg2+ binding site [chemical binding]; other site 291112005657 Switch I region; other site 291112005658 G2 box; other site 291112005659 Switch II region; other site 291112005660 G3 box; other site 291112005661 G4 box; other site 291112005662 G5 box; other site 291112005663 EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895 291112005664 G1 box; other site 291112005665 GTP/Mg2+ binding site [chemical binding]; other site 291112005666 Switch I region; other site 291112005667 G2 box; other site 291112005668 G3 box; other site 291112005669 Switch II region; other site 291112005670 G4 box; other site 291112005671 G5 box; other site 291112005672 HMMPfam hit to PF01926, GTPase of unknown function, score 1.3e-45 291112005673 HMMPfam hit to PF01926, GTPase of unknown function, score 1.2e-45 291112005674 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 291112005675 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 291112005676 active site 291112005677 Zn binding site [ion binding]; other site 291112005678 HMMPfam hit to PF02868, Thermolysin metallopeptidase, alpha-he, score 2.6e-31 291112005679 HMMPfam hit to PF01447, Thermolysin metallopeptidase, catalyti, score 6.7e-26 291112005680 coproporphyrinogen III oxidase; Provisional; Region: PRK05330 291112005681 Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218 291112005682 HMMPfam hit to PF01218, Coproporphyrinogen III oxidase, score 2.3e-208 291112005683 putative acetyltransferase; Provisional; Region: PRK03624 291112005684 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112005685 Coenzyme A binding pocket [chemical binding]; other site 291112005686 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.9e-16 291112005687 Periplasmic protein with OB-fold [Function unknown]; Region: COG3111 291112005688 HMMPfam hit to PF04076, Domain unknown function (DUF388), score 3.3e-48 291112005689 RpoE-regulated lipoprotein; Provisional; Region: PRK10718 291112005690 Protein of unknown function (DUF1131); Region: DUF1131; pfam06572 291112005691 HMMPfam hit to PF06572, Protein of unknown function (DUF1131), score 8.9e-89 291112005692 thiosulfate transporter subunit; Provisional; Region: PRK10852 291112005693 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 291112005694 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 1e-06 291112005695 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 291112005696 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112005697 dimer interface [polypeptide binding]; other site 291112005698 conserved gate region; other site 291112005699 putative PBP binding loops; other site 291112005700 ABC-ATPase subunit interface; other site 291112005701 7 probable transmembrane helices predicted for PAT4086 by TMHMM2.0 at aa 20-42, 63-85, 105-127, 134-156, 183-205, 212-234 and 244-266 291112005702 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8e-38 291112005703 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112005704 dimer interface [polypeptide binding]; other site 291112005705 conserved gate region; other site 291112005706 putative PBP binding loops; other site 291112005707 ABC-ATPase subunit interface; other site 291112005708 6 probable transmembrane helices predicted for PAT4085 by TMHMM2.0 at aa 20-42, 69-91, 103-125, 140-162, 201-223 and 246-268 291112005709 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3.5e-16 291112005710 sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851 291112005711 ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296 291112005712 Walker A/P-loop; other site 291112005713 ATP binding site [chemical binding]; other site 291112005714 Q-loop/lid; other site 291112005715 ABC transporter signature motif; other site 291112005716 Walker B; other site 291112005717 D-loop; other site 291112005718 H-loop/switch region; other site 291112005719 TOBE-like domain; Region: TOBE_3; pfam12857 291112005720 HMMSmart hit to SM00382, no description, score 1.8e-18 291112005721 HMMPfam hit to PF00005, ABC transporter, score 1e-72 291112005722 cysteine synthase B; Region: cysM; TIGR01138 291112005723 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 291112005724 dimer interface [polypeptide binding]; other site 291112005725 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112005726 catalytic residue [active] 291112005727 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1e-104 291112005728 PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210 291112005729 HPr interaction site; other site 291112005730 glycerol kinase (GK) interaction site [polypeptide binding]; other site 291112005731 active site 291112005732 phosphorylation site [posttranslational modification] 291112005733 HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 1.3e-78 291112005734 phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177 291112005735 PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524 291112005736 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 291112005737 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 291112005738 HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 2.6e-186 291112005739 HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 5.2e-31 291112005740 HMMPfam hit to PF05524, PEP-utilising enzyme, N-terminal, score 6.3e-55 291112005741 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 291112005742 dimerization domain swap beta strand [polypeptide binding]; other site 291112005743 regulatory protein interface [polypeptide binding]; other site 291112005744 active site 291112005745 regulatory phosphorylation site [posttranslational modification]; other site 291112005746 HMMPfam hit to PF00381, PTS HPr component phosphorylation site, score 6.1e-47 291112005747 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 291112005748 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 291112005749 dimer interface [polypeptide binding]; other site 291112005750 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112005751 catalytic residue [active] 291112005752 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 3.3e-125 291112005753 putative sulfate transport protein CysZ; Validated; Region: PRK04949 291112005754 HMMPfam hit to PF04401, Protein of unknown function (DUF540), score 1e-98 291112005755 4 probable transmembrane helices predicted for PAT4078 by TMHMM2.0 at aa 32-51, 71-93, 152-174 and 221-243 291112005756 cell division protein ZipA; Provisional; Region: PRK03427 291112005757 ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231 291112005758 FtsZ protein binding site [polypeptide binding]; other site 291112005759 1 probable transmembrane helix predicted for PAT4077 by TMHMM2.0 at aa 5-27 291112005760 HMMPfam hit to PF04354, ZipA, C-terminal FtsZ-binding domain, score 6.2e-74 291112005761 NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956 291112005762 NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114 291112005763 nucleotide binding pocket [chemical binding]; other site 291112005764 K-X-D-G motif; other site 291112005765 catalytic site [active] 291112005766 NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120 291112005767 NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119 291112005768 Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027 291112005769 Dimer interface [polypeptide binding]; other site 291112005770 BRCT sequence motif; other site 291112005771 HMMPfam hit to PF01653, NAD-dependent DNA ligase adenylation, score 3.3e-198 291112005772 HMMSmart hit to SM00532, no description, score 3e-280 291112005773 HMMPfam hit to PF03120, NAD-dependent DNA ligase OB-fold doma, score 8.9e-52 291112005774 HMMPfam hit to PF03119, NAD-dependent DNA ligase C4 zinc fing, score 8.9e-11 291112005775 HMMSmart hit to SM00278, no description, score 9.5 291112005776 HMMSmart hit to SM00278, no description, score 1.9 291112005777 HMMSmart hit to SM00278, no description, score 2.2e+02 291112005778 HMMSmart hit to SM00278, no description, score 2.4e+02 291112005779 HMMPfam hit to PF00533, BRCA1 C Terminus (BRCT) domain, score 8.9e-20 291112005780 HMMSmart hit to SM00292, no description, score 1.3e-13 291112005781 Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972 291112005782 Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773 291112005783 Nucleoside recognition; Region: Gate; pfam07670 291112005784 Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662 291112005785 8 probable transmembrane helices predicted for PAT4075 by TMHMM2.0 at aa 63-85, 92-109, 148-170, 228-250, 254-276, 309-331, 397-419 and 432-454 291112005786 HMMPfam hit to PF01773, Na+ dependent nucleoside transporter N, score 1.7e-31 291112005787 HMMPfam hit to PF07670, Nucleoside recognition, score 1.4e-15 291112005788 HMMPfam hit to PF07662, Na+ dependent nucleoside transporter C, score 7.9e-103 291112005789 Protein of unknown function (DUF3820); Region: DUF3820; pfam12843 291112005790 glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406 291112005791 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 291112005792 active site 291112005793 HIGH motif; other site 291112005794 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 291112005795 active site 291112005796 KMSKS motif; other site 291112005797 HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), cata, score 2.3e-173 291112005798 glucokinase; Provisional; Region: glk; PRK00292 291112005799 glucokinase, proteobacterial type; Region: glk; TIGR00749 291112005800 HMMPfam hit to PF02685, Glucokinase, score 8.5e-184 291112005801 ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091 291112005802 HMMPfam hit to PF04333, VacJ like lipoprotein, score 2.4e-107 291112005803 long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716 291112005804 HMMPfam hit to PF03349, Outer membrane protein transport protein (O, score 4e-171 291112005805 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691 291112005806 HMMPfam hit to PF04175, Protein of unknown function (DUF406), score 2.1e-44 291112005807 3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963 291112005808 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 291112005809 dimer interface [polypeptide binding]; other site 291112005810 active site 291112005811 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 4.1e-63 291112005812 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 5.9e-52 291112005813 multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154 291112005814 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 291112005815 substrate binding site [chemical binding]; other site 291112005816 oxyanion hole (OAH) forming residues; other site 291112005817 trimer interface [polypeptide binding]; other site 291112005818 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 291112005819 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 291112005820 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 291112005821 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.6e-68 291112005822 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 9.8e-77 291112005823 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 2.3e-34 291112005824 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 0.00038 291112005825 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 291112005826 catalytic core [active] 291112005827 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 2.7e-15 291112005828 hypothetical protein; Provisional; Region: PRK04946 291112005829 Smr domain; Region: Smr; pfam01713 291112005830 HMMSmart hit to SM00463, no description, score 1.9e-19 291112005831 HMMPfam hit to PF01713, Smr domain, score 1e-29 291112005832 imidazolonepropionase; Validated; Region: PRK09356 291112005833 Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296 291112005834 active site 291112005835 HMMPfam hit to PF01979, Amidohydrolase family, score 3.6e-06 291112005836 HMMPfam hit to PF07969, Amidohydrolase family, score 0.00029 291112005837 Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988 291112005838 putative active site [active] 291112005839 putative metal binding site [ion binding]; other site 291112005840 HMMPfam hit to PF00491, Arginase family, score 2.1e-10 291112005841 histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018 291112005842 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 291112005843 DNA-binding site [nucleotide binding]; DNA binding site 291112005844 UTRA domain; Region: UTRA; pfam07702 291112005845 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 3.8e-22 291112005846 HMMSmart hit to SM00345, no description, score 5.8e-18 291112005847 HMMPfam hit to PF07702, UTRA domain, score 3.8e-35 291112005848 urocanate hydratase; Provisional; Region: PRK05414 291112005849 HMMPfam hit to PF01175, Urocanase, score 0 291112005850 Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332 291112005851 active sites [active] 291112005852 tetramer interface [polypeptide binding]; other site 291112005853 HMMPfam hit to PF00221, Phenylalanine and histidine ammonia-lyase, score 1.1e-255 291112005854 putative proline-specific permease; Provisional; Region: proY; PRK10580 291112005855 HMMPfam hit to PF00324, Amino acid permease, score 7.7e-122 291112005856 13 probable transmembrane helices predicted for PAT4059 by TMHMM2.0 at aa 15-34, 41-63, 78-95, 100-119, 124-146, 153-175, 198-220, 241-263, 278-300, 329-351, 356-378, 398-420 and 425-447 291112005857 HemK family putative methylases; Region: hemK_fam; TIGR00536 291112005858 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112005859 S-adenosylmethionine binding site [chemical binding]; other site 291112005860 HMMPfam hit to PF05175, Methyltransferase small domain, score 1.3e-09 291112005861 Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082 291112005862 Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304 291112005863 Tetramer interface [polypeptide binding]; other site 291112005864 active site 291112005865 FMN-binding site [chemical binding]; other site 291112005866 HMMPfam hit to PF01264, Chorismate synthase, score 1.6e-230 291112005867 hypothetical protein; Provisional; Region: PRK10621 291112005868 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 291112005869 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 3.1e-50 291112005870 8 probable transmembrane helices predicted for PAT4056 by TMHMM2.0 at aa 13-35, 55-74, 81-100, 104-126, 138-155, 159-176, 196-218 and 233-250 291112005871 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101 291112005872 HMMPfam hit to PF04315, Protein of unknown function, DUF462, score 4.2e-136 291112005873 YfcL protein; Region: YfcL; pfam08891 291112005874 Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016 291112005875 HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 1e-21 291112005876 RelB antitoxin; Region: RelB; cl01171 291112005877 HMMPfam hit to PF04221, RelB antitoxin, score 1.1e-09 291112005878 bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747 291112005879 Uncharacterized conserved protein [Function unknown]; Region: COG4121 291112005880 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 1.1e-57 291112005881 HMMPfam hit to PF05430, Protein of unknown function (DUF752), score 7.7e-136 291112005882 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 291112005883 HMMPfam hit to PF01810, LysE type translocator, score 2.5e-25 291112005884 5 probable transmembrane helices predicted for PAT4050 by TMHMM2.0 at aa 35-57, 78-100, 104-123, 144-166 and 176-198 291112005885 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 291112005886 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 291112005887 putative DNA binding site [nucleotide binding]; other site 291112005888 putative Zn2+ binding site [ion binding]; other site 291112005889 AsnC family; Region: AsnC_trans_reg; pfam01037 291112005890 HMMSmart hit to SM00344, no description, score 1.1e-42 291112005891 HMMPfam hit to PF01037, AsnC family, score 1.2e-24 291112005892 2 probable transmembrane helices predicted for PAT4048 by TMHMM2.0 at aa 4-21 and 33-50 291112005893 3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967 291112005894 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 291112005895 dimer interface [polypeptide binding]; other site 291112005896 active site 291112005897 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 1.2e-57 291112005898 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 7.3e-60 291112005899 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333 291112005900 12 probable transmembrane helices predicted for PAT4044 by TMHMM2.0 at aa 20-42, 62-84, 110-132, 142-164, 171-193, 208-230, 260-282, 321-343, 356-378, 382-404, 406-428 and 470-492 291112005901 HMMPfam hit to PF01970, Integral membrane protein DUF112, score 1.8e-217 291112005902 Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331 291112005903 4 probable transmembrane helices predicted for PAT4043 by TMHMM2.0 at aa 5-23, 38-55, 67-89 and 104-126 291112005904 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181 291112005905 HMMPfam hit to PF03401, Bordetella uptake gene (bug) product, score 2.6e-08 291112005906 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 291112005907 transcriptional regulatory protein TctD; Provisional; Region: PRK15479 291112005908 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112005909 active site 291112005910 phosphorylation site [posttranslational modification] 291112005911 intermolecular recognition site; other site 291112005912 dimerization interface [polypeptide binding]; other site 291112005913 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112005914 DNA binding site [nucleotide binding] 291112005915 HMMPfam hit to PF00072, Response regulator receiver domain, score 7.7e-36 291112005916 HMMSmart hit to SM00448, no description, score 7.8e-40 291112005917 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 9.8e-20 291112005918 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 291112005919 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112005920 dimer interface [polypeptide binding]; other site 291112005921 phosphorylation site [posttranslational modification] 291112005922 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112005923 ATP binding site [chemical binding]; other site 291112005924 Mg2+ binding site [ion binding]; other site 291112005925 G-X-G motif; other site 291112005926 2 probable transmembrane helices predicted for PAT4038 by TMHMM2.0 at aa 15-37 and 170-192 291112005927 HMMPfam hit to PF08521, Two-component sensor kinase N-terminal, score 1.5e-76 291112005928 HMMPfam hit to PF00672, HAMP domain, score 7.1e-09 291112005929 HMMSmart hit to SM00304, no description, score 0.0068 291112005930 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 3.5e-14; HMMSmart hit to SM00388, no description, score 1.8e-12 291112005931 HMMSmart hit to SM00387, no description, score 1.4e-18 291112005932 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.7e-19 291112005933 EamA-like transporter family; Region: EamA; pfam00892 291112005934 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 291112005935 EamA-like transporter family; Region: EamA; pfam00892 291112005936 10 probable transmembrane helices predicted for PAT4037 by TMHMM2.0 at aa 5-27, 31-53, 66-85, 90-112, 114-136, 146-168, 181-200, 210-229, 242-259 and 269-291 291112005937 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 3.8e-22 291112005938 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 3.8e-19 291112005939 Helix-turn-helix domain; Region: HTH_18; pfam12833 291112005940 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112005941 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 0.00016 291112005942 erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438 291112005943 D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158 291112005944 ligand binding site [chemical binding]; other site 291112005945 NAD binding site [chemical binding]; other site 291112005946 catalytic site [active] 291112005947 homodimer interface [polypeptide binding]; other site 291112005948 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 5.1e-25 291112005949 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 3e-29 291112005950 putative semialdehyde dehydrogenase; Provisional; Region: PRK08040 291112005951 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 291112005952 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindi, score 2.3e-40 291112005953 HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisat, score 6.5e-35 291112005954 tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021 291112005955 Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA; Region: PseudoU_synth_EcTruA; cd02570 291112005956 dimerization interface 3.5A [polypeptide binding]; other site 291112005957 active site 291112005958 HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 1.8e-37 291112005959 HMMPfam hit to PF01416, tRNA pseudouridine synthase, score 8.4e-26 291112005960 hypothetical protein; Provisional; Region: PRK10847 291112005961 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 291112005962 4 probable transmembrane helices predicted for PAT4032 by TMHMM2.0 at aa 36-58, 78-100, 163-185 and 195-217 291112005963 acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654 291112005964 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682 291112005965 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846 291112005966 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 291112005967 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 291112005968 HMMPfam hit to PF08245, Mur ligase middle domain, score 3.1e-07 291112005969 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 0.00031 291112005970 cell division protein DedD; Provisional; Region: PRK11633 291112005971 Sporulation related domain; Region: SPOR; pfam05036 291112005972 1 probable transmembrane helix predicted for PAT4029 by TMHMM2.0 at aa 10-27 291112005973 HMMPfam hit to PF05036, Sporulation related domain, score 4.9e-11 291112005974 colicin V production protein; Provisional; Region: PRK10845 291112005975 Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286 291112005976 HMMPfam hit to PF02674, Colicin V production protein, score 8.9e-64 291112005977 4 probable transmembrane helices predicted for PAT4028 by TMHMM2.0 at aa 4-26, 31-53, 63-85 and 98-120 291112005978 amidophosphoribosyltransferase; Provisional; Region: PRK09246 291112005979 Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715 291112005980 active site 291112005981 tetramer interface [polypeptide binding]; other site 291112005982 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112005983 active site 291112005984 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 7.2e-57 291112005985 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 3.1e-12 291112005986 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029 291112005987 Flavoprotein; Region: Flavoprotein; pfam02441 291112005988 HMMPfam hit to PF02441, Flavoprotein, score 2.4e-46 291112005989 Region 3 291112005990 Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090 291112005991 atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242 291112005992 putative NAD(P) binding site [chemical binding]; other site 291112005993 putative active site [active] 291112005994 HMMPfam hit to PF08338, Domain of unknown function (DUF1731), score 8.4e-22 291112005995 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 1.6e-08 291112005996 GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972 291112005997 GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048 291112005998 C-terminal domain interface [polypeptide binding]; other site 291112005999 GSH binding site (G-site) [chemical binding]; other site 291112006000 dimer interface [polypeptide binding]; other site 291112006001 C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291 291112006002 N-terminal domain interface [polypeptide binding]; other site 291112006003 putative dimer interface [polypeptide binding]; other site 291112006004 active site 291112006005 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 1.8e-11 291112006006 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 1.8e-09 291112006007 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112006008 active site flap/lid [active] 291112006009 nucleophilic elbow; other site 291112006010 catalytic triad [active] 291112006011 HMMPfam hit to PF01764, Lipase (class 3), score 5.2e-17 291112006012 NUDIX hydrolase YfcD; Provisional; Region: PRK15393 291112006013 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697 291112006014 nudix motif; other site 291112006015 HMMPfam hit to PF00293, NUDIX domain, score 1.1e-20 291112006016 Protein of unknown function (DUF4225); Region: DUF4225; pfam13988 291112006017 3 probable transmembrane helices predicted for PAT4019 by TMHMM2.0 at aa 15-34, 46-65 and 85-107 291112006018 Protein of unknown function (DUF796); Region: DUF796; cl01226 291112006019 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 1.5e-07 291112006020 Protein of unknown function (DUF796); Region: DUF796; cl01226 291112006021 autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486 291112006022 HMMPfam hit to PF03992, Antibiotic biosynthesis monooxygenase, score 1.4e-16 291112006023 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830 291112006024 Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958 291112006025 putative active site; other site 291112006026 catalytic residue [active] 291112006027 HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 2.6e-10 291112006028 transcriptional regulator LsrR; Provisional; Region: PRK15418 291112006029 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320 291112006030 non-specific DNA interactions [nucleotide binding]; other site 291112006031 DNA binding site [nucleotide binding] 291112006032 sequence specific DNA binding site [nucleotide binding]; other site 291112006033 putative cAMP binding site [chemical binding]; other site 291112006034 Putative sugar-binding domain; Region: Sugar-bind; pfam04198 291112006035 HMMPfam hit to PF00325, Bacterial regulatory proteins, crp family, score 0.0016 291112006036 HMMPfam hit to PF04198, Putative sugar-binding domain, score 1.8e-84 291112006037 autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939 291112006038 Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775 291112006039 putative N- and C-terminal domain interface [polypeptide binding]; other site 291112006040 putative active site [active] 291112006041 putative MgATP binding site [chemical binding]; other site 291112006042 catalytic site [active] 291112006043 metal binding site [ion binding]; metal-binding site 291112006044 putative carbohydrate binding site [chemical binding]; other site 291112006045 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 291112006046 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 1.4e-45 291112006047 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 8.1e-08 291112006048 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112006049 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112006050 acyl-activating enzyme (AAE) consensus motif; other site 291112006051 AMP binding site [chemical binding]; other site 291112006052 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112006053 Condensation domain; Region: Condensation; pfam00668 291112006054 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112006055 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112006056 acyl-activating enzyme (AAE) consensus motif; other site 291112006057 AMP binding site [chemical binding]; other site 291112006058 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112006059 Condensation domain; Region: Condensation; pfam00668 291112006060 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112006061 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112006062 acyl-activating enzyme (AAE) consensus motif; other site 291112006063 AMP binding site [chemical binding]; other site 291112006064 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112006065 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 291112006066 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.4e-169 291112006067 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 3.2e-13 291112006068 HMMPfam hit to PF00668, Condensation domain, score 2.3e-19 291112006069 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.1e-165 291112006070 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.2e-15 291112006071 HMMPfam hit to PF00668, Condensation domain, score 1.2e-24 291112006072 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.1e-161 291112006073 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 8.9e-11 291112006074 HMMPfam hit to PF00975, Thioesterase domain, score 2.1e-16 291112006075 1 probable transmembrane helix predicted for PAT4011 by TMHMM2.0 at aa 5-24 291112006076 2 probable transmembrane helices predicted for PAT4007 by TMHMM2.0 at aa 12-36 and 51-73 291112006077 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 291112006078 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112006079 Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210 291112006080 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112006081 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112006082 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112006083 Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829 291112006084 HMMPfam hit to PF05860, haemagglutination activity domain, score 9.7e-47 291112006085 Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831 291112006086 POTRA domain, ShlB-type; Region: POTRA_2; pfam08479 291112006087 Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865 291112006088 HMMPfam hit to PF03865, Haemolysin secretion/activation protein ShlB, score 3.4e-11 291112006089 Homeodomain-like domain; Region: HTH_23; cl17451 291112006090 Helix-turn-helix domain; Region: HTH_28; pfam13518 291112006091 putative transposase OrfB; Reviewed; Region: PHA02517 291112006092 HTH-like domain; Region: HTH_21; pfam13276 291112006093 Integrase core domain; Region: rve; pfam00665 291112006094 Integrase core domain; Region: rve_2; pfam13333 291112006095 HMMPfam hit to PF00665, Integrase core domain, score 2.2e-42 291112006096 POTRA domain, ShlB-type; Region: POTRA_2; pfam08479 291112006097 Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826 291112006098 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112006099 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112006100 acyl-activating enzyme (AAE) consensus motif; other site 291112006101 AMP binding site [chemical binding]; other site 291112006102 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112006103 Condensation domain; Region: Condensation; pfam00668 291112006104 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112006105 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112006106 acyl-activating enzyme (AAE) consensus motif; other site 291112006107 AMP binding site [chemical binding]; other site 291112006108 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112006109 Condensation domain; Region: Condensation; pfam00668 291112006110 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112006111 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112006112 acyl-activating enzyme (AAE) consensus motif; other site 291112006113 AMP binding site [chemical binding]; other site 291112006114 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112006115 Condensation domain; Region: Condensation; pfam00668 291112006116 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112006117 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112006118 acyl-activating enzyme (AAE) consensus motif; other site 291112006119 AMP binding site [chemical binding]; other site 291112006120 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112006121 Condensation domain; Region: Condensation; pfam00668 291112006122 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112006123 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112006124 acyl-activating enzyme (AAE) consensus motif; other site 291112006125 AMP binding site [chemical binding]; other site 291112006126 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112006127 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 291112006128 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.1e-162 291112006129 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 3.8e-16 291112006130 HMMPfam hit to PF00668, Condensation domain, score 2.8e-25 291112006131 HMMPfam hit to PF00501, AMP-binding enzyme, score 5.6e-153 291112006132 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.4e-15 291112006133 HMMPfam hit to PF00668, Condensation domain, score 3e-23 291112006134 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.1e-162 291112006135 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 6.6e-18 291112006136 HMMPfam hit to PF00668, Condensation domain, score 2.6e-24 291112006137 HMMPfam hit to PF00501, AMP-binding enzyme, score 4e-158 291112006138 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 5.2e-15 291112006139 HMMPfam hit to PF00668, Condensation domain, score 2.1e-31 291112006140 HMMPfam hit to PF00501, AMP-binding enzyme, score 6.9e-163 291112006141 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 9.1e-11 291112006142 HMMPfam hit to PF00975, Thioesterase domain, score 6.8e-17 291112006143 1 probable transmembrane helix predicted for PAT3992 by TMHMM2.0 at aa 7-29 291112006144 hypothetical protein; Provisional; Region: PRK09956 291112006145 Putative transposase, YhgA-like; Region: Transposase_31; pfam04754 291112006146 HMMPfam hit to PF04754, Putative transposase, YhgA-like, score 1.8e-187 291112006147 bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381 291112006148 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 291112006149 inhibitor-cofactor binding pocket; inhibition site 291112006150 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112006151 catalytic residue [active] 291112006152 HMMPfam hit to PF00202, Aminotransferase class-III, score 8.1e-155 291112006153 Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138 291112006154 Arginine N-succinyltransferase beta subunit; Region: AstA; cl11440 291112006155 HMMPfam hit to PF04958, Arginine N-succinyltransferase beta subunit, score 2.5e-170 291112006156 succinylglutamic semialdehyde dehydrogenase; Region: arg_catab_astD; TIGR03240 291112006157 N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095 291112006158 NAD(P) binding site [chemical binding]; other site 291112006159 catalytic residues [active] 291112006160 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2.5e-125 291112006161 succinylarginine dihydrolase; Provisional; Region: PRK13281 291112006162 HMMPfam hit to PF04996, Succinylarginine dihydrolase, score 1.5e-270 291112006163 succinylglutamate desuccinylase; Provisional; Region: PRK05324 291112006164 Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952 291112006165 active site 291112006166 Zn binding site [ion binding]; other site 291112006167 HMMPfam hit to PF04952, Succinylglutamate desuccinylase / Aspartoac, score 4e-59 291112006168 D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049 291112006169 12 probable transmembrane helices predicted for PAT3982 by TMHMM2.0 at aa 25-47, 52-74, 111-133, 138-160, 167-189, 209-231, 259-281, 285-307, 346-368, 378-400, 417-439 and 443-461 291112006170 HMMPfam hit to PF00324, Amino acid permease, score 2.8e-108 291112006171 Predicted nuclease of the RNAse H fold, HicB family [General function prediction only]; Region: COG1598 291112006172 HMMPfam hit to PF03681, Uncharacterised protein family (UPF0150), score 3e-15 291112006173 YcfA-like protein; Region: YcfA; pfam07927 291112006174 HMMPfam hit to PF07927, YcfA-like protein, score 2.2e-21 291112006175 similar to INSD:BX571869; similar to INSD:D17576 291112006176 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 291112006177 active site 291112006178 iron coordination sites [ion binding]; other site 291112006179 substrate binding pocket [chemical binding]; other site 291112006180 hypothetical protein; Provisional; Region: PRK10621 291112006181 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 291112006182 7 probable transmembrane helices predicted for PAT3973 by TMHMM2.0 at aa 5-39, 73-95, 99-118, 130-152, 157-179, 186-208 and 228-247 291112006183 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 1.8e-35 291112006184 phosphate acetyltransferase; Reviewed; Region: PRK05632 291112006185 DRTGG domain; Region: DRTGG; pfam07085 291112006186 phosphate acetyltransferase; Region: pta; TIGR00651 291112006187 HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 1.1e-187 291112006188 HMMPfam hit to PF07085, DRTGG domain, score 6.4e-57 291112006189 propionate/acetate kinase; Provisional; Region: PRK12379 291112006190 acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180 291112006191 HMMPfam hit to PF00871, Acetokinase family, score 9.2e-246 291112006192 hypothetical protein; Provisional; Region: PRK01816 291112006193 HMMPfam hit to PF04217, Protein of unknown function, DUF412, score 4e-80 291112006194 Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115 291112006195 transmembrane helices; other site 291112006196 Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471 291112006197 TrkA-C domain; Region: TrkA_C; pfam02080 291112006198 TrkA-C domain; Region: TrkA_C; pfam02080 291112006199 Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115 291112006200 11 probable transmembrane helices predicted for PAT3969 by TMHMM2.0 at aa 4-21, 28-47, 57-76, 97-119, 139-161, 173-195, 429-451, 464-483, 503-525, 544-566 and 586-608 291112006201 HMMPfam hit to PF06808, DctM-like transporters, score 0.0002 291112006202 HMMPfam hit to PF03600, Citrate transporter, score 1.6e-49 291112006203 HMMPfam hit to PF02080, TrkA-C domain, score 1e-12 291112006204 HMMPfam hit to PF02080, TrkA-C domain, score 2.5e-10 291112006205 5'-nucleotidase; Provisional; Region: PRK03826 291112006206 HMMSmart hit to SM00471, no description, score 9.1e-09 291112006207 HMMPfam hit to PF01966, HD domain, score 1.2e-10 291112006208 aminotransferase AlaT; Validated; Region: PRK09265 291112006209 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112006210 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112006211 homodimer interface [polypeptide binding]; other site 291112006212 catalytic residue [active] 291112006213 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.4e-42 291112006214 DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092 291112006215 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112006216 The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439 291112006217 putative dimerization interface [polypeptide binding]; other site 291112006218 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.2e-16 291112006219 HMMPfam hit to PF03466, LysR substrate binding domain, score 6.1e-24 291112006220 NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602 291112006221 3 probable transmembrane helices predicted for PAT3964 by TMHMM2.0 at aa 15-37, 68-90 and 100-122 291112006222 HMMPfam hit to PF00507, NADH-ubiquinone/plastoquinone oxidoreduct, score 8.7e-40 291112006223 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377 291112006224 HMMPfam hit to PF01058, NADH ubiquinone oxidoreductase, 20 Kd sub, score 1.1e-54 291112006225 bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742 291112006226 NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961 291112006227 NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338 291112006228 HMMPfam hit to PF00329, Respiratory-chain NADH dehydrogenase,, score 2.9e-42 291112006229 HMMPfam hit to PF00346, Respiratory-chain NADH dehydrogenase,, score 2.2e-172 291112006230 NADH dehydrogenase subunit E; Validated; Region: PRK07539 291112006231 TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064 291112006232 putative dimer interface [polypeptide binding]; other site 291112006233 [2Fe-2S] cluster binding site [ion binding]; other site 291112006234 HMMPfam hit to PF01257, Respiratory-chain NADH dehydrogenase, score 6.7e-86 291112006235 NADH dehydrogenase I subunit F; Provisional; Region: PRK11278 291112006236 SLBB domain; Region: SLBB; pfam10531 291112006237 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589 291112006238 HMMPfam hit to PF01512, Respiratory-chain NADH dehydrogenase, score 9.5e-174 291112006239 NADH dehydrogenase subunit G; Validated; Region: PRK08166 291112006240 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 291112006241 catalytic loop [active] 291112006242 iron binding site [ion binding]; other site 291112006243 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588 291112006244 MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771 291112006245 [4Fe-4S] binding site [ion binding]; other site 291112006246 MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788 291112006247 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding dom, score 6.5e-12 291112006248 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 dom, score 2.8e-12 291112006249 NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076 291112006250 HMMPfam hit to PF00146, NADH dehydrogenase, score 9e-164 291112006251 8 probable transmembrane helices predicted for PAT3958 by TMHMM2.0 at aa 13-35, 82-104, 114-136, 149-171, 186-208, 236-258, 268-290 and 299-321 291112006252 NADH dehydrogenase subunit I; Provisional; Region: PRK05888 291112006253 4Fe-4S binding domain; Region: Fer4; pfam00037 291112006254 4Fe-4S binding domain; Region: Fer4; pfam00037 291112006255 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 9.2e-05 291112006256 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.8e-08 291112006257 NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839 291112006258 5 probable transmembrane helices predicted for PAT3956 by TMHMM2.0 at aa 4-21, 28-50, 55-77, 90-112 and 137-159 291112006259 HMMPfam hit to PF00499, NADH-ubiquinone/plastoquinone oxidoreduct, score 6.9e-32 291112006260 NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715 291112006261 3 probable transmembrane helices predicted for PAT3955 by TMHMM2.0 at aa 4-23, 28-50 and 60-82 291112006262 HMMPfam hit to PF00420, NADH-ubiquinone/plastoquinone oxidoreduct, score 1.1e-32 291112006263 NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590 291112006264 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662 291112006265 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 291112006266 17 probable transmembrane helices predicted for PAT3954 by TMHMM2.0 at aa 4-21, 28-50, 80-102, 115-134, 139-161, 174-196, 216-238, 251-270, 280-302, 309-331, 335-357, 378-400, 415-437, 458-480, 495-517, 530-552 and 592-614 291112006267 HMMPfam hit to PF00662, NADH-Ubiquinone oxidoreductase (complex, score 3.6e-29 291112006268 HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex, score 1.2e-117 291112006269 NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846 291112006270 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 291112006271 12 probable transmembrane helices predicted for PAT3953 by TMHMM2.0 at aa 4-18, 30-49, 85-107, 120-142, 175-197, 218-240, 288-307, 314-331, 341-363, 383-405, 418-440 and 461-483 291112006272 HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), score 3.5e-80 291112006273 mGOT4n 291112006274 NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777 291112006275 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 291112006276 14 probable transmembrane helices predicted for PAT3952 by TMHMM2.0 at aa 6-28, 35-57, 72-94, 107-126, 130-147, 159-181, 201-223, 236-258, 268-290, 297-316, 326-348, 371-393, 408-427 and 448-470 291112006277 HMMPfam hit to PF00361, NADH-Ubiquinone/plastoquinone (complex I), score 1.3e-89 291112006278 1 probable transmembrane helix predicted for PAT3950 by TMHMM2.0 at aa 261-283 291112006279 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449 291112006280 Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037 291112006281 dimer interface [polypeptide binding]; other site 291112006282 tetramer interface [polypeptide binding]; other site 291112006283 PYR/PP interface [polypeptide binding]; other site 291112006284 TPP binding site [chemical binding]; other site 291112006285 Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009 291112006286 TPP-binding site; other site 291112006287 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126 291112006288 Protein of unknown function (DUF1343); Region: DUF1343; cl01598 291112006289 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.0002 291112006290 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 291112006291 Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378 291112006292 substrate binding site [chemical binding]; other site 291112006293 oxyanion hole (OAH) forming residues; other site 291112006294 trimer interface [polypeptide binding]; other site 291112006295 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.3e-69 291112006296 O-succinylbenzoate synthase; Provisional; Region: PRK05105 291112006297 o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320 291112006298 active site 291112006299 O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029 291112006300 O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912 291112006301 acyl-activating enzyme (AAE) consensus motif; other site 291112006302 putative AMP binding site [chemical binding]; other site 291112006303 putative active site [active] 291112006304 putative CoA binding site [chemical binding]; other site 291112006305 HMMPfam hit to PF00501, AMP-binding enzyme, score 8e-58 291112006306 Domain of unknown function (DUF4258); Region: DUF4258; pfam14076 291112006307 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112006308 non-specific DNA binding site [nucleotide binding]; other site 291112006309 salt bridge; other site 291112006310 sequence-specific DNA binding site [nucleotide binding]; other site 291112006311 Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753 291112006312 Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156 291112006313 tetramer interface [polypeptide binding]; other site 291112006314 heme binding pocket [chemical binding]; other site 291112006315 NADPH binding site [chemical binding]; other site 291112006316 HMMPfam hit to PF00199, Catalase, score 1.8e-284 291112006317 YfaZ precursor; Region: YfaZ; pfam07437 291112006318 outer membrane protein; Region: OMP_w_GlyGly; TIGR04219 291112006319 HMMPfam hit to PF07437, YfaZ precursor, score 9.6e-78 291112006320 1 probable transmembrane helix predicted for PAT3938 by TMHMM2.0 at aa 4-26 291112006321 tyrosine transporter TyrP; Provisional; Region: PRK15132 291112006322 aromatic amino acid transport protein; Region: araaP; TIGR00837 291112006323 11 probable transmembrane helices predicted for PAT3937 by TMHMM2.0 at aa 7-29, 33-55, 81-103, 118-137, 149-168, 183-205, 218-240, 273-295, 308-330, 334-356 and 375-397 291112006324 HMMPfam hit to PF01490, Transmembrane amino acid transporter pro, score 0.00033 291112006325 HMMPfam hit to PF03222, Tryptophan/tyrosine permease family, score 6.2e-168 291112006326 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112006327 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112006328 Possible hemagglutinin (DUF637); Region: DUF637; pfam04830 291112006329 HMMPfam hit to PF05860, haemagglutination activity domain, score 3.1e-52 291112006330 HMMPfam hit to PF05594, Haemagluttinin repeat, score 0.00019 291112006331 HMMPfam hit to PF04830, Possible hemagglutinin (DUF637), score 1.8e-08 291112006332 Protein of unknown function (DUF1436); Region: DUF1436; pfam07262 291112006333 HMMPfam hit to PF07262, Protein of unknown function (DUF1436), score 1.1e-37 291112006334 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 291112006335 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 291112006336 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 291112006337 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 1.3e-09 291112006338 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 9e-36 291112006339 1 probable transmembrane helix predicted for PAT3931 by TMHMM2.0 at aa 27-49 291112006340 Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633 291112006341 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 291112006342 catalytic loop [active] 291112006343 iron binding site [ion binding]; other site 291112006344 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 4.5e-10 291112006345 Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049 291112006346 dimer interface [polypeptide binding]; other site 291112006347 putative radical transfer pathway; other site 291112006348 diiron center [ion binding]; other site 291112006349 tyrosyl radical; other site 291112006350 HMMPfam hit to PF00268, Ribonucleotide reductase, small chain, score 8.2e-09 291112006351 ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103 291112006352 ATP cone domain; Region: ATP-cone; pfam03477 291112006353 Class I ribonucleotide reductase; Region: RNR_I; cd01679 291112006354 active site 291112006355 dimer interface [polypeptide binding]; other site 291112006356 catalytic residues [active] 291112006357 effector binding site; other site 291112006358 R2 peptide binding site; other site 291112006359 HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 4.7e-257 291112006360 HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha d, score 6.6e-23 291112006361 HMMPfam hit to PF03477, ATP cone domain, score 2.3e-21 291112006362 bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134 291112006363 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112006364 S-adenosylmethionine binding site [chemical binding]; other site 291112006365 HMMPfam hit to PF08241, Methyltransferase domain, score 2.4e-26 291112006366 HMMPfam hit to PF08242, Methyltransferase domain, score 4.5e-18 291112006367 DNA gyrase subunit A; Validated; Region: PRK05560 291112006368 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 291112006369 CAP-like domain; other site 291112006370 active site 291112006371 primary dimer interface [polypeptide binding]; other site 291112006372 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 291112006373 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 291112006374 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 291112006375 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 291112006376 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 291112006377 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 291112006378 HMMSmart hit to SM00434, no description, score 5.5e-299 291112006379 HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 0 291112006380 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 2.7e-14 291112006381 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 4e-15 291112006382 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 1.2e-09 291112006383 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 7.4e-15 291112006384 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 2.4e-15 291112006385 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 7e-16 291112006386 hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841 291112006387 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112006388 dimer interface [polypeptide binding]; other site 291112006389 phosphorylation site [posttranslational modification] 291112006390 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112006391 ATP binding site [chemical binding]; other site 291112006392 Mg2+ binding site [ion binding]; other site 291112006393 G-X-G motif; other site 291112006394 RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456 291112006395 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112006396 active site 291112006397 phosphorylation site [posttranslational modification] 291112006398 intermolecular recognition site; other site 291112006399 dimerization interface [polypeptide binding]; other site 291112006400 2 probable transmembrane helices predicted for PAT3925 by TMHMM2.0 at aa 20-42 and 317-339 291112006401 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.8e-23; HMMSmart hit to SM00388, no description, score 2.3e-21 291112006402 HMMSmart hit to SM00387, no description, score 4.6e-35 291112006403 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 2e-39 291112006404 HMMPfam hit to PF00072, Response regulator receiver domain, score 6.4e-37 291112006405 HMMSmart hit to SM00448, no description, score 3.2e-35 291112006406 transcriptional regulator RcsB; Provisional; Region: PRK10840 291112006407 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112006408 active site 291112006409 phosphorylation site [posttranslational modification] 291112006410 intermolecular recognition site; other site 291112006411 dimerization interface [polypeptide binding]; other site 291112006412 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112006413 DNA binding residues [nucleotide binding] 291112006414 dimerization interface [polypeptide binding]; other site 291112006415 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 3.6e-19; HMMSmart hit to SM00421, no description, score 1.4e-14 291112006416 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.1e-22 291112006417 HMMSmart hit to SM00448, no description, score 1.8e-11 291112006418 phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618 291112006419 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112006420 ATP binding site [chemical binding]; other site 291112006421 Mg2+ binding site [ion binding]; other site 291112006422 G-X-G motif; other site 291112006423 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 291112006424 putative binding surface; other site 291112006425 active site 291112006426 HMMPfam hit to PF01627, Hpt domain, score 6e-11 291112006427 HMMSmart hit to SM00387, no description, score 0.00022 291112006428 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2.8e-09 291112006429 1 probable transmembrane helix predicted for PAT3923 by TMHMM2.0 at aa 13-35 291112006430 Stress responsive A/B Barrel Domain; Region: Dabb; pfam07876 291112006431 HMMPfam hit to PF07876, Stress responsive A/B Barrel Domain, score 3.9e-22 291112006432 Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530 291112006433 HMMPfam hit to PF06530, Phage antitermination protein Q, score 1.7e-56 291112006434 Protein of unknown function (DUF3383); Region: DUF3383; pfam11863 291112006435 Protein of unknown function (DUF3277); Region: DUF3277; pfam11681 291112006436 virion protein; Provisional; Region: V; PHA02564 291112006437 Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812 291112006438 Baseplate J-like protein; Region: Baseplate_J; cl01294 291112006439 Protein of unknown function (DUF2612); Region: DUF2612; pfam11041 291112006440 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112006441 HMMPfam hit to PF03406, Phage tail fibre repeat, score 1.3e-08 291112006442 HMMPfam hit to PF03406, Phage tail fibre repeat, score 4.8 291112006443 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112006444 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 291112006445 HMMPfam hit to PF00534, Glycosyl transferases group, score 1.2e-17 291112006446 Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532 291112006447 HMMPfam hit to PF01755, Glycosyltransferase family 25 (LPS bi, score 7.1e-25 291112006448 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112006449 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 1.6e-34 291112006450 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 291112006451 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 291112006452 putative active site [active] 291112006453 HMMPfam hit to PF01075, Glycosyltransferase family, score 1.4e-07 291112006454 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112006455 Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194 291112006456 Sulfatase; Region: Sulfatase; cl17466 291112006457 5 probable transmembrane helices predicted for PAT3897 by TMHMM2.0 at aa 7-29, 34-52, 57-76, 96-118 and 130-147 291112006458 HMMPfam hit to PF00884, Sulfatase, score 1.8e-40 291112006459 3 probable transmembrane helices predicted for PAT3896 by TMHMM2.0 at aa 7-24, 34-56 and 63-80 291112006460 Methyltransferase domain; Region: Methyltransf_31; pfam13847 291112006461 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112006462 S-adenosylmethionine binding site [chemical binding]; other site 291112006463 HMMPfam hit to PF08241, Methyltransferase domain, score 2.6e-06 291112006464 HMMPfam hit to PF08242, Methyltransferase domain, score 0.0016 291112006465 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112006466 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 1.1e-39 291112006467 Phage Tail Collar Domain; Region: Collar; pfam07484 291112006468 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 2.9e-20 291112006469 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112006470 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112006471 non-specific DNA binding site [nucleotide binding]; other site 291112006472 salt bridge; other site 291112006473 sequence-specific DNA binding site [nucleotide binding]; other site 291112006474 HMMSmart hit to SM00530, no description, score 6.4e-11 291112006475 HMMPfam hit to PF01381, Helix-turn-helix, score 1.6e-10 291112006476 Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681 291112006477 3 probable transmembrane helices predicted for PAT3890 by TMHMM2.0 at aa 13-35, 39-56 and 63-85 291112006478 1 probable transmembrane helix predicted for PAT3889 by TMHMM2.0 at aa 15-37 291112006479 Methyltransferase domain; Region: Methyltransf_31; pfam13847 291112006480 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112006481 S-adenosylmethionine binding site [chemical binding]; other site 291112006482 HMMPfam hit to PF08241, Methyltransferase domain, score 2.8e-05 291112006483 Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381 291112006484 HMMPfam hit to PF06192, Cytoplasmic chaperone TorD, score 1.1e-47 291112006485 cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077 291112006486 dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090 291112006487 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130 291112006488 catalytic triad [active] 291112006489 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 3.5e-42 291112006490 HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 2.3e-41 291112006491 cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209 291112006492 HMMPfam hit to PF03186, CobD/Cbib protein, score 3.2e-138 291112006493 4 probable transmembrane helices predicted for PAT3882 by TMHMM2.0 at aa 54-76, 155-177, 204-226 and 294-316 291112006494 cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286 291112006495 Precorrin-8X methylmutase; Region: CbiC; pfam02570 291112006496 HMMPfam hit to PF02570, Precorrin-8X methylmutase, score 1.1e-44 291112006497 cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075 291112006498 HMMPfam hit to PF01888, CbiD, score 5.9e-163 291112006499 Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644 291112006500 active site 291112006501 putative homodimer interface [polypeptide binding]; other site 291112006502 SAM binding site [chemical binding]; other site 291112006503 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 1.1e-24 291112006504 cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287 291112006505 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112006506 S-adenosylmethionine binding site [chemical binding]; other site 291112006507 HMMPfam hit to PF08242, Methyltransferase domain, score 0.00012 291112006508 Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641 291112006509 active site 291112006510 SAM binding site [chemical binding]; other site 291112006511 homodimer interface [polypeptide binding]; other site 291112006512 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 1.3e-64 291112006513 cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788 291112006514 Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760 291112006515 Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761 291112006516 Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890 291112006517 HMMPfam hit to PF01890, CbiG, score 4.4e-107 291112006518 Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646 291112006519 active site 291112006520 SAM binding site [chemical binding]; other site 291112006521 homodimer interface [polypeptide binding]; other site 291112006522 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 7.1e-61 291112006523 Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099 291112006524 cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057 291112006525 HMMPfam hit to PF02571, Precorrin-6x reductase CbiJ/CobK, score 4.5e-40 291112006526 Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822 291112006527 Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412 291112006528 active site 291112006529 C-terminal domain interface [polypeptide binding]; other site 291112006530 Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413 291112006531 active site 291112006532 N-terminal domain interface [polypeptide binding]; other site 291112006533 HMMPfam hit to PF06180, Cobalt chelatase (CbiK), score 6.3e-132 291112006534 Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645 291112006535 active site 291112006536 SAM binding site [chemical binding]; other site 291112006537 homodimer interface [polypeptide binding]; other site 291112006538 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 4.9e-33 291112006539 cobyric acid synthase; Provisional; Region: PRK00784 291112006540 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 291112006541 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 291112006542 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750 291112006543 catalytic triad [active] 291112006544 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 3.8e-58 291112006545 HMMPfam hit to PF07685, CobB/CobQ-like glutamine amidotransferase do, score 1.1e-73 291112006546 Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544 291112006547 homotrimer interface [polypeptide binding]; other site 291112006548 Walker A motif; other site 291112006549 GTP binding site [chemical binding]; other site 291112006550 Walker B motif; other site 291112006551 HMMPfam hit to PF02283, Cobinamide kinase / cobinamide phosphate gua, score 1.7e-72 291112006552 cobalamin synthase; Reviewed; Region: cobS; PRK00235 291112006553 HMMPfam hit to PF02654, Cobalamin-5-phosphate synthase, score 1.7e-62 291112006554 5 probable transmembrane helices predicted for PAT3869 by TMHMM2.0 at aa 35-57, 110-132, 137-159, 180-198 and 203-220 291112006555 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112006556 non-specific DNA binding site [nucleotide binding]; other site 291112006557 salt bridge; other site 291112006558 sequence-specific DNA binding site [nucleotide binding]; other site 291112006559 HMMSmart hit to SM00530, no description, score 3.7e-05 291112006560 HMMPfam hit to PF01381, Helix-turn-helix, score 9.9e-08 291112006561 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 291112006562 catalytic core [active] 291112006563 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 3.3e-44 291112006564 Phosphoribosyltransferase; Region: DBI_PRT; pfam02277 291112006565 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439 291112006566 putative dimer interface [polypeptide binding]; other site 291112006567 active site pocket [active] 291112006568 putative cataytic base [active] 291112006569 HMMPfam hit to PF02277, Phosphoribosyltransferase, score 3.7e-157 291112006570 Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681 291112006571 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112006572 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 9.2e-53 291112006573 Protein of unknown function (DUF4225); Region: DUF4225; pfam13988 291112006574 2 probable transmembrane helices predicted for PAT3861 by TMHMM2.0 at aa 54-76 and 86-108 291112006575 2 probable transmembrane helices predicted for PAT3860 by TMHMM2.0 at aa 52-74 and 84-106 291112006576 2 probable transmembrane helices predicted for PAT3859 by TMHMM2.0 at aa 52-74 and 84-106 291112006577 2 probable transmembrane helices predicted for PAT3858 by TMHMM2.0 at aa 48-79 and 94-116 291112006578 2 probable transmembrane helices predicted for PAT3857 by TMHMM2.0 at aa 63-80 and 84-106 291112006579 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112006580 salt bridge; other site 291112006581 non-specific DNA binding site [nucleotide binding]; other site 291112006582 sequence-specific DNA binding site [nucleotide binding]; other site 291112006583 HMMSmart hit to SM00530, no description, score 8.2e-08 291112006584 HMMPfam hit to PF01381, Helix-turn-helix, score 1.3e-09 291112006585 Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302 291112006586 HMMPfam hit to PF05985, Ethanolamine ammonia-lyase light chain (EutC, score 3.3e-128 291112006587 ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067 291112006588 Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751 291112006589 HMMPfam hit to PF06751, Ethanolamine ammonia lyase large subunit (Eu, score 2.1e-297 291112006590 reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719 291112006591 HMMPfam hit to PF06277, Ethanolamine utilisation protein EutA, score 1.9e-225 291112006592 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 291112006593 active site 291112006594 SAM binding site [chemical binding]; other site 291112006595 homodimer interface [polypeptide binding]; other site 291112006596 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 3.1e-81 291112006597 threonine-phosphate decarboxylase; Provisional; Region: PRK08056 291112006598 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112006599 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112006600 homodimer interface [polypeptide binding]; other site 291112006601 catalytic residue [active] 291112006602 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1e-30 291112006603 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542 291112006604 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 291112006605 HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 7.1e-11 291112006606 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648 291112006607 Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241 291112006608 Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414 291112006609 ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109 291112006610 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561 291112006611 homodimer interface [polypeptide binding]; other site 291112006612 Walker A motif; other site 291112006613 ATP binding site [chemical binding]; other site 291112006614 hydroxycobalamin binding site [chemical binding]; other site 291112006615 Walker B motif; other site 291112006616 HMMPfam hit to PF02572, ATP:corrinoid adenosyltransferase BtuR, score 6.5e-66 291112006617 Predicted transcriptional regulator [Transcription]; Region: COG2944 291112006618 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112006619 non-specific DNA binding site [nucleotide binding]; other site 291112006620 salt bridge; other site 291112006621 sequence-specific DNA binding site [nucleotide binding]; other site 291112006622 HMMPfam hit to PF01381, Helix-turn-helix, score 1.5e-06 291112006623 HMMSmart hit to SM00530, no description, score 6.1e-06 291112006624 Protein of unknown function (DUF1044); Region: DUF1044; cl01955 291112006625 HMMPfam hit to PF06296, Protein of unknown function (DUF1044), score 2.6e-08 291112006626 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 291112006627 trimer interface [polypeptide binding]; other site 291112006628 HMMPfam hit to PF05658, Hep_Hag, score 0.67 291112006629 HMMPfam hit to PF05658, Hep_Hag, score 0.037 291112006630 HMMPfam hit to PF05658, Hep_Hag, score 0.0012 291112006631 HMMPfam hit to PF05662, Haemagglutinin, score 0.00018 291112006632 1 probable transmembrane helix predicted for PAT3842 by TMHMM2.0 at aa 15-34 291112006633 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 291112006634 Coenzyme A binding pocket [chemical binding]; other site 291112006635 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 5.1e-11 291112006636 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112006637 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 6.1e-23 291112006638 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112006639 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112006640 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 4.1e-18 291112006641 Phage Tail Collar Domain; Region: Collar; pfam07484 291112006642 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 5.1e-16 291112006643 Phage Tail Collar Domain; Region: Collar; pfam07484 291112006644 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 2.8e-19 291112006645 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112006646 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 8.8e-29 291112006647 Phage Tail Collar Domain; Region: Collar; pfam07484 291112006648 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 1.3e-22 291112006649 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112006650 Phage Tail Collar Domain; Region: Collar; pfam07484 291112006651 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 2.6e-14 291112006652 Phage Tail Collar Domain; Region: Collar; pfam07484 291112006653 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 8.5e-20 291112006654 Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826 291112006655 Integrase core domain; Region: rve; pfam00665 291112006656 HMMPfam hit to PF00665, Integrase core domain, score 4.6e-07 291112006657 Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826 291112006658 Helix-turn-helix domain; Region: HTH_38; pfam13936 291112006659 Homeodomain-like domain; Region: HTH_32; pfam13565 291112006660 Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532 291112006661 HMMPfam hit to PF01755, Glycosyltransferase family 25 (LPS bi, score 7.2e-41 291112006662 Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083 291112006663 Domain of unknown function (DUF3413); Region: DUF3413; pfam11893 291112006664 Sulfatase; Region: Sulfatase; cl17466 291112006665 HMMPfam hit to PF00884, Sulfatase, score 1.2e-20 291112006666 5 probable transmembrane helices predicted for PAT3821 by TMHMM2.0 at aa 21-43, 58-80, 85-107, 135-157 and 168-190 291112006667 hypothetical protein; Provisional; Region: PRK13689 291112006668 HMMPfam hit to PF07208, Protein of unknown function (DUF1414), score 8.4e-42 291112006669 nucleoid-associated protein NdpA; Validated; Region: PRK00378 291112006670 Nucleoid-associated protein [General function prediction only]; Region: COG3081 291112006671 HMMPfam hit to PF04245, 37-kD nucleoid-associated bacterial protein, score 5.9e-178 291112006672 Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495 291112006673 5S rRNA interface [nucleotide binding]; other site 291112006674 CTC domain interface [polypeptide binding]; other site 291112006675 L16 interface [polypeptide binding]; other site 291112006676 HMMPfam hit to PF01386, Ribosomal L25p family, score 1.4e-48 291112006677 DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061 291112006678 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112006679 ATP binding site [chemical binding]; other site 291112006680 putative Mg++ binding site [ion binding]; other site 291112006681 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112006682 nucleotide binding region [chemical binding]; other site 291112006683 ATP-binding site [chemical binding]; other site 291112006684 Double zinc ribbon; Region: DZR; pfam12773 291112006685 HMMSmart hit to SM00490, no description, score 1.7e-06 291112006686 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 4.5e-07 291112006687 HMMSmart hit to SM00487, no description, score 1.9e-20 291112006688 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 7.2e-11 291112006689 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 6e-38 291112006690 16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839 291112006691 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 291112006692 RNA binding surface [nucleotide binding]; other site 291112006693 Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553 291112006694 active site 291112006695 uracil binding [chemical binding]; other site 291112006696 HMMSmart hit to SM00363, no description, score 1.9e-08 291112006697 HMMPfam hit to PF01479, S4 domain, score 4.8e-09 291112006698 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 1.1e-22 291112006699 bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102 291112006700 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112006701 putative substrate translocation pore; other site 291112006702 12 probable transmembrane helices predicted for PAT3814 by TMHMM2.0 at aa 7-29, 47-69, 76-98, 102-124, 137-159, 163-185, 214-236, 251-273, 282-304, 308-330, 342-364 and 368-390 291112006703 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.2e-53 291112006704 hypothetical protein; Provisional; Region: PRK11835 291112006705 outer membrane lipoprotein; Provisional; Region: spr; PRK10838 291112006706 NlpC/P60 family; Region: NLPC_P60; pfam00877 291112006707 HMMPfam hit to PF00877, NlpC/P60 family, score 3.7e-49 291112006708 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 291112006709 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610 291112006710 active site 291112006711 HMMPfam hit to PF01569, PAP2 superfamily, score 9e-09 291112006712 5 probable transmembrane helices predicted for PAT3810 by TMHMM2.0 at aa 7-26, 59-81, 93-115, 160-182 and 189-211 291112006713 HMMSmart hit to SM00014, no description, score 1.3e-09 291112006714 elongation factor P; Provisional; Region: PRK04542 291112006715 Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207 291112006716 S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470 291112006717 RNA binding site [nucleotide binding]; other site 291112006718 S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794 291112006719 RNA binding site [nucleotide binding]; other site 291112006720 HMMPfam hit to PF01132, Elongation factor P (EF-P) OB domain, score 2.4e-23 291112006721 HMMPfam hit to PF08207, Elongation factor P (EF-P) KOW-like domain, score 8.6e-22 291112006722 Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316 291112006723 aromatic amino acid transport protein; Region: araaP; TIGR00837 291112006724 HMMPfam hit to PF01490, Transmembrane amino acid transporter pro, score 0.0005 291112006725 11 probable transmembrane helices predicted for PAT3807 by TMHMM2.0 at aa 13-35, 39-61, 91-113, 123-145, 152-174, 194-216, 229-251, 286-308, 328-345, 349-371 and 391-410 291112006726 HMMPfam hit to PF03222, Tryptophan/tyrosine permease family, score 1.3e-193 291112006727 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_19; cd04678 291112006728 nudix motif; other site 291112006729 HMMPfam hit to PF00293, NUDIX domain, score 2.6e-22 291112006730 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105 291112006731 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164 291112006732 putative substrate binding site [chemical binding]; other site 291112006733 putative ATP binding site [chemical binding]; other site 291112006734 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.5e-62 291112006735 endonuclease IV; Provisional; Region: PRK01060 291112006736 AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019 291112006737 AP (apurinic/apyrimidinic) site pocket; other site 291112006738 DNA interaction; other site 291112006739 Metal-binding active site; metal-binding site 291112006740 HMMSmart hit to SM00518, no description, score 2e-129 291112006741 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 1.4e-61 291112006742 Predicted membrane protein [Function unknown]; Region: COG2855 291112006743 9 probable transmembrane helices predicted for PAT3803 by TMHMM2.0 at aa 20-42, 47-69, 104-126, 136-155, 167-189, 239-256, 277-299, 304-326 and 333-355 291112006744 HMMPfam hit to PF03601, Conserved hypothetical protein, score 4.7e-146 291112006745 putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837 291112006746 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112006747 C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420 291112006748 putative dimerization interface [polypeptide binding]; other site 291112006749 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.6e-18 291112006750 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.4e-45 291112006751 lysine transporter; Provisional; Region: PRK10836 291112006752 HMMPfam hit to PF00324, Amino acid permease, score 6.7e-187 291112006753 12 probable transmembrane helices predicted for PAT3801 by TMHMM2.0 at aa 25-44, 54-76, 97-119, 134-156, 163-185, 205-227, 248-270, 294-316, 350-369, 373-395, 416-438 and 448-470 291112006754 ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048 291112006755 Periplasmic binding protein TroA_f. These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139 291112006756 putative ligand binding residues [chemical binding]; other site 291112006757 HMMPfam hit to PF01497, Periplasmic binding protein, score 3.9e-06 291112006758 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 291112006759 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112006760 ABC-ATPase subunit interface; other site 291112006761 dimer interface [polypeptide binding]; other site 291112006762 putative PBP binding regions; other site 291112006763 9 probable transmembrane helices predicted for PAT3799 by TMHMM2.0 at aa 5-27, 47-69, 82-104, 114-136, 143-165, 185-207, 237-259, 274-293 and 300-322 291112006764 HMMPfam hit to PF01032, FecCD transport family, score 5.9e-77 291112006765 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 291112006766 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 291112006767 Walker A/P-loop; other site 291112006768 ATP binding site [chemical binding]; other site 291112006769 Q-loop/lid; other site 291112006770 ABC transporter signature motif; other site 291112006771 Walker B; other site 291112006772 D-loop; other site 291112006773 H-loop/switch region; other site 291112006774 HMMSmart hit to SM00382, no description, score 7e-14 291112006775 HMMPfam hit to PF00005, ABC transporter, score 2.9e-47 291112006776 putative outer membrane receptor; Provisional; Region: PRK13513 291112006777 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 291112006778 N-terminal plug; other site 291112006779 ligand-binding site [chemical binding]; other site 291112006780 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 6.6e-29 291112006781 HMMPfam hit to PF00593, TonB dependent receptor, score 2.9e-26 291112006782 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 291112006783 12 probable transmembrane helices predicted for PAT3795 by TMHMM2.0 at aa 26-44, 59-81, 102-124, 139-161, 166-188, 208-225, 245-267, 287-309, 345-364, 369-391, 403-420 and 430-449 291112006784 HMMPfam hit to PF00324, Amino acid permease, score 1.2e-16 291112006785 Protein of unknown function (DUF3100); Region: DUF3100; pfam11299 291112006786 D-lactate dehydrogenase; Provisional; Region: PRK11183 291112006787 FAD binding domain; Region: FAD_binding_4; pfam01565 291112006788 D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330 291112006789 HMMPfam hit to PF01565, FAD binding domain, score 2.3e-05 291112006790 exonuclease I; Provisional; Region: sbcB; PRK11779 291112006791 N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138 291112006792 active site 291112006793 catalytic site [active] 291112006794 substrate binding site [chemical binding]; other site 291112006795 Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411 291112006796 HMMPfam hit to PF08411, Exonuclease C-terminal, score 1.4e-174 291112006797 HMMSmart hit to SM00479, no description, score 0.0042 291112006798 HMMPfam hit to PF00929, Exonuclease, score 1.6e-29 291112006799 1 probable transmembrane helix predicted for PAT3790 by TMHMM2.0 at aa 4-26 291112006800 1 probable transmembrane helix predicted for PAT3789 by TMHMM2.0 at aa 13-35 291112006801 hypothetical protein; Provisional; Region: PRK05423 291112006802 HMMPfam hit to PF04363, Protein of unknown function (DUF496), score 8.7e-63 291112006803 atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243 291112006804 NADH(P)-binding; Region: NAD_binding_10; pfam13460 291112006805 NAD(P) binding site [chemical binding]; other site 291112006806 putative active site [active] 291112006807 HMMPfam hit to PF05368, NmrA-like family, score 0.00028 291112006808 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.002 291112006809 ribonuclease E; Reviewed; Region: rne; PRK10811 291112006810 S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453 291112006811 homodimer interface [polypeptide binding]; other site 291112006812 oligonucleotide binding site [chemical binding]; other site 291112006813 Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111 291112006814 HMMPfam hit to PF00575, S1 RNA binding domain, score 4.3e-20 291112006815 HMMSmart hit to SM00316, no description, score 4.3e-13 291112006816 23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025 291112006817 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 291112006818 RNA binding surface [nucleotide binding]; other site 291112006819 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 291112006820 active site 291112006821 HMMSmart hit to SM00363, no description, score 3.3e-08 291112006822 HMMPfam hit to PF01479, S4 domain, score 5.8e-11 291112006823 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 7.1e-54 291112006824 Maf-like protein; Region: Maf; pfam02545 291112006825 Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555 291112006826 active site 291112006827 dimer interface [polypeptide binding]; other site 291112006828 HMMPfam hit to PF02545, Maf-like protein, score 1.1e-62 291112006829 hypothetical protein; Provisional; Region: PRK11193 291112006830 HMMPfam hit to PF02620, Uncharacterized ACR, COG1399, score 5.8e-49 291112006831 50S ribosomal protein L32; Validated; Region: rpmF; PRK01110 291112006832 HMMPfam hit to PF01783, Ribosomal L32p protein family, score 8.7e-25 291112006833 putative phosphate acyltransferase; Provisional; Region: PRK05331 291112006834 HMMPfam hit to PF02504, Fatty acid synthesis protein, score 1.5e-143 291112006835 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352 291112006836 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 291112006837 dimer interface [polypeptide binding]; other site 291112006838 active site 291112006839 CoA binding pocket [chemical binding]; other site 291112006840 HMMPfam hit to PF08545, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 4.1e-44 291112006841 HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 4.6e-53 291112006842 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331 291112006843 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 291112006844 HMMPfam hit to PF00698, Acyl transferase domain, score 1.2e-11 291112006845 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 291112006846 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 291112006847 NAD(P) binding site [chemical binding]; other site 291112006848 homotetramer interface [polypeptide binding]; other site 291112006849 homodimer interface [polypeptide binding]; other site 291112006850 active site 291112006851 HMMPfam hit to PF00106, short chain dehydrogenase, score 7.3e-35 291112006852 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0014 291112006853 acyl carrier protein; Provisional; Region: acpP; PRK00982 291112006854 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 5.1e-22 291112006855 3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314 291112006856 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 291112006857 dimer interface [polypeptide binding]; other site 291112006858 active site 291112006859 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 7.1e-82 291112006860 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 2.9e-75 291112006861 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 291112006862 ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559 291112006863 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112006864 catalytic residue [active] 291112006865 HMMPfam hit to PF01063, Aminotransferase class IV, score 2.1e-35 291112006866 Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559 291112006867 proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010 291112006868 dimerization interface [polypeptide binding]; other site 291112006869 1 probable transmembrane helix predicted for PAT3774 by TMHMM2.0 at aa 7-26 291112006870 HMMPfam hit to PF02618, Aminodeoxychorismate lyase, score 1.7e-139 291112006871 thymidylate kinase; Validated; Region: tmk; PRK00698 291112006872 Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672 291112006873 TMP-binding site; other site 291112006874 ATP-binding site [chemical binding]; other site 291112006875 HMMPfam hit to PF02223, Thymidylate kinase, score 8.5e-82 291112006876 DNA polymerase III subunit delta'; Validated; Region: PRK07993 291112006877 DNA polymerase III subunit delta'; Validated; Region: PRK08485 291112006878 DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115 291112006879 TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310 291112006880 Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099 291112006881 active site 291112006882 HMMPfam hit to PF01026, TatD related DNase, score 5.4e-118 291112006883 Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276 291112006884 nucleotide binding site/active site [active] 291112006885 HIT family signature motif; other site 291112006886 catalytic residue [active] 291112006887 HMMPfam hit to PF01230, HIT domain, score 9.9e-54 291112006888 Protein of unknown function (DUF3897); Region: DUF3897; cl17494 291112006889 thiamine kinase; Region: ycfN_thiK; TIGR02721 291112006890 active site 291112006891 substrate binding site [chemical binding]; other site 291112006892 ATP binding site [chemical binding]; other site 291112006893 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 291112006894 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 9e-22 291112006895 HMMPfam hit to PF01633, Choline/ethanolamine kinase, score 7.2e-09 291112006896 1 probable transmembrane helix predicted for PAT3767 by TMHMM2.0 at aa 15-37 291112006897 Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472 291112006898 beta-hexosaminidase; Provisional; Region: PRK05337 291112006899 HMMPfam hit to PF00933, Glycosyl hydrolase family 3 N terminal, score 4.1e-76 291112006900 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252 291112006901 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 291112006902 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 3e-23 291112006903 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 2.7e-20 291112006904 Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404 291112006905 Peptidase S8 family domain, uncharacterized subfamily 11; Region: Peptidases_S8_11; cd04843 291112006906 putative active site [active] 291112006907 putative catalytic triad [active] 291112006908 HMMPfam hit to PF00082, Subtilase family, score 2.1e-08 291112006909 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 291112006910 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112006911 Coenzyme A binding pocket [chemical binding]; other site 291112006912 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 4e-16 291112006913 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 291112006914 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 291112006915 substrate binding pocket [chemical binding]; other site 291112006916 active site 291112006917 iron coordination sites [ion binding]; other site 291112006918 HMMPfam hit to PF02668, Taurine catabolism dioxygenase TauD, TfdA fa, score 2.9e-56 291112006919 Pyoverdine/dityrosine biosynthesis protein [Secondary metabolites biosynthesis, transport, and catabolism]; Region: DIT1; COG3207 291112006920 Pyoverdine/dityrosine biosynthesis protein; Region: DIT1_PvcA; pfam05141 291112006921 HMMPfam hit to PF05141, Pyoverdine/dityrosine biosynthesis protein, score 2.2e-115 291112006922 transcription-repair coupling factor; Provisional; Region: PRK10689 291112006923 CarD-like/TRCF domain; Region: CarD_TRCF; smart01058 291112006924 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112006925 ATP binding site [chemical binding]; other site 291112006926 putative Mg++ binding site [ion binding]; other site 291112006927 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112006928 nucleotide binding region [chemical binding]; other site 291112006929 ATP-binding site [chemical binding]; other site 291112006930 This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982 291112006931 HMMPfam hit to PF03461, TRCF domain, score 2.3e-48 291112006932 HMMSmart hit to SM00490, no description, score 1.7e-18 291112006933 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 4.2e-20 291112006934 HMMSmart hit to SM00487, no description, score 2e-32 291112006935 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 3.3e-41 291112006936 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 1.5e-06 291112006937 HMMPfam hit to PF02559, CarD-like/TRCF domain, score 1.7e-48 291112006938 1 probable transmembrane helix predicted for PAT3757 by TMHMM2.0 at aa 20-37 291112006939 outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814 291112006940 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 291112006941 FtsX-like permease family; Region: FtsX; pfam02687 291112006942 4 probable transmembrane helices predicted for PAT3756 by TMHMM2.0 at aa 25-47, 270-292, 313-335 and 364-386 291112006943 HMMPfam hit to PF02687, Predicted permease, score 1.3e-40 291112006944 lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629 291112006945 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 291112006946 Walker A/P-loop; other site 291112006947 ATP binding site [chemical binding]; other site 291112006948 Q-loop/lid; other site 291112006949 ABC transporter signature motif; other site 291112006950 Walker B; other site 291112006951 D-loop; other site 291112006952 H-loop/switch region; other site 291112006953 HMMSmart hit to SM00382, no description, score 4.5e-14 291112006954 HMMPfam hit to PF00005, ABC transporter, score 5e-64 291112006955 outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146 291112006956 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 291112006957 FtsX-like permease family; Region: FtsX; pfam02687 291112006958 4 probable transmembrane helices predicted for PAT3754 by TMHMM2.0 at aa 21-43, 271-293, 319-341 and 381-400 291112006959 HMMPfam hit to PF02687, Predicted permease, score 3.6e-51 291112006960 NAD-dependent deacetylase; Provisional; Region: PRK00481 291112006961 SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412 291112006962 NAD+ binding site [chemical binding]; other site 291112006963 substrate binding site [chemical binding]; other site 291112006964 Zn binding site [ion binding]; other site 291112006965 HMMPfam hit to PF02146, Sir2 family, score 8.3e-78 291112006966 peptidase T; Region: peptidase-T; TIGR01882 291112006967 M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892 291112006968 metal binding site [ion binding]; metal-binding site 291112006969 dimer interface [polypeptide binding]; other site 291112006970 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 0.00015 291112006971 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 7.7e-26 291112006972 Uncharacterized conserved protein [Function unknown]; Region: COG2850 291112006973 HMMPfam hit to PF08007, Cupin superfamily protein, score 1.8e-155 291112006974 HMMSmart hit to SM00558, no description, score 1.5e-07 291112006975 sensor protein PhoQ; Provisional; Region: PRK10815 291112006976 PhoQ Sensor; Region: PhoQ_Sensor; pfam08918 291112006977 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 291112006978 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112006979 dimer interface [polypeptide binding]; other site 291112006980 phosphorylation site [posttranslational modification] 291112006981 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112006982 ATP binding site [chemical binding]; other site 291112006983 Mg2+ binding site [ion binding]; other site 291112006984 G-X-G motif; other site 291112006985 HMMSmart hit to SM00387, no description, score 2.5e-22 291112006986 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.9e-26 291112006987 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 0.00055 291112006988 HMMPfam hit to PF00672, HAMP domain, score 5e-07 291112006989 2 probable transmembrane helices predicted for PAT3749 by TMHMM2.0 at aa 20-42 and 194-216 291112006990 DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816 291112006991 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112006992 active site 291112006993 phosphorylation site [posttranslational modification] 291112006994 intermolecular recognition site; other site 291112006995 dimerization interface [polypeptide binding]; other site 291112006996 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112006997 DNA binding site [nucleotide binding] 291112006998 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 3e-11 291112006999 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.7e-29 291112007000 HMMSmart hit to SM00448, no description, score 5.4e-37 291112007001 adenylosuccinate lyase; Provisional; Region: PRK09285 291112007002 PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598 291112007003 tetramer interface [polypeptide binding]; other site 291112007004 active site 291112007005 HMMPfam hit to PF08328, Adenylosuccinate lyase C-terminal, score 3.5e-90 291112007006 HMMPfam hit to PF00206, Lyase, score 1.3e-93 291112007007 putative lysogenization regulator; Reviewed; Region: PRK00218 291112007008 HMMPfam hit to PF04356, Protein of unknown function (DUF489), score 3.1e-110 291112007009 tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054 291112007010 tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998 291112007011 HMMPfam hit to PF03054, tRNA methyl transferase, score 3.6e-229 291112007012 HMMPfam hit to PF01171, PP-loop family, score 0.095 291112007013 Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675 291112007014 nudix motif; other site 291112007015 HMMPfam hit to PF00293, NUDIX domain, score 1.1e-23 291112007016 Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130 291112007017 pseudouridine synthase; Region: TIGR00093 291112007018 active site 291112007019 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 6.8e-10 291112007020 isocitrate dehydrogenase; Validated; Region: PRK07362 291112007021 isocitrate dehydrogenase; Reviewed; Region: PRK07006 291112007022 HMMPfam hit to PF00180, Isocitrate/isopropylmalate dehydrogenase, score 1.5e-165 291112007023 Haemagglutinin; Region: Hemagglutinin; pfam00509 291112007024 1 probable transmembrane helix predicted for PAT3741 by TMHMM2.0 at aa 112-134 291112007025 1 probable transmembrane helix predicted for PAT3739 by TMHMM2.0 at aa 13-35 291112007026 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 291112007027 amino acid carrier protein; Region: agcS; TIGR00835 291112007028 10 probable transmembrane helices predicted for PAT3737 by TMHMM2.0 at aa 13-35, 91-113, 141-163, 178-200, 207-224, 234-256, 301-323, 350-372, 385-407 and 417-439 291112007029 HMMPfam hit to PF01235, Sodium:alanine symporter family, score 5.1e-220 291112007030 N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023 291112007031 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 291112007032 amidase catalytic site [active] 291112007033 Zn binding residues [ion binding]; other site 291112007034 substrate binding site [chemical binding]; other site 291112007035 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 291112007036 HMMSmart hit to SM00644, no description, score 1.7e-26 291112007037 HMMPfam hit to PF01510, N-acetylmuramoyl-L-alanine amidase, score 3.1e-36 291112007038 HMMPfam hit to PF01471, Putative peptidoglycan binding domain, score 1.7e-08 291112007039 4 probable transmembrane helices predicted for PAT3735 by TMHMM2.0 at aa 21-43, 58-80, 92-111 and 115-134 291112007040 Predicted small integral membrane protein (DUF2165); Region: DUF2165; pfam09933 291112007041 4 probable transmembrane helices predicted for PAT3734 by TMHMM2.0 at aa 13-35, 69-91, 103-125 and 140-157 291112007042 aromatic amino acid exporter; Provisional; Region: PRK11689 291112007043 EamA-like transporter family; Region: EamA; cl17759 291112007044 10 probable transmembrane helices predicted for PAT3733 by TMHMM2.0 at aa 13-35, 45-67, 72-94, 99-121, 128-145, 165-184, 196-213, 223-245, 252-274 and 278-297 291112007045 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 0.0019 291112007046 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 0.00046 291112007047 sugar phosphate phosphatase; Provisional; Region: PRK10513 291112007048 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112007049 active site 291112007050 motif I; other site 291112007051 motif II; other site 291112007052 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112007053 HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 2.8e-05 291112007054 HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 2.5e-75 291112007055 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.00011 291112007056 DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219 291112007057 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112007058 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7.2e-13 291112007059 HMMSmart hit to SM00342, no description, score 6.5e-28 291112007060 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 3.1e-08 291112007061 MgrB protein; Region: MgrB; pfam13998 291112007062 1 probable transmembrane helix predicted for PAT3730 by TMHMM2.0 at aa 15-33 291112007063 aromatic amino acid transporter; Provisional; Region: PRK10238 291112007064 HMMPfam hit to PF00324, Amino acid permease, score 1.5e-141 291112007065 12 probable transmembrane helices predicted for PAT3728 by TMHMM2.0 at aa 21-40, 44-61, 98-120, 124-146, 153-175, 198-220, 240-262, 282-304, 331-353, 357-379, 399-421 and 425-444 291112007066 phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045 291112007067 HMMPfam hit to PF07017, Antimicrobial peptide resistance and lipid A, score 1.9e-103 291112007068 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 291112007069 DNA-binding site [nucleotide binding]; DNA binding site 291112007070 RNA-binding motif; other site 291112007071 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 1.5e-45 291112007072 HMMSmart hit to SM00357, no description, score 1.7e-34 291112007073 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 291112007074 substrate binding site [chemical binding]; other site 291112007075 dimer interface [polypeptide binding]; other site 291112007076 ATP binding site [chemical binding]; other site 291112007077 HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase, score 6.2e-139 291112007078 fructose-bisphosphate aldolase; Provisional; Region: PRK09250 291112007079 Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958 291112007080 putative active site; other site 291112007081 catalytic residue [active] 291112007082 HMMPfam hit to PF01791, DeoC/LacD family aldolase, score 3.5e-82 291112007083 Beta protein; Region: Beta_protein; pfam14350 291112007084 putative protease; Provisional; Region: PRK15452 291112007085 Peptidase family U32; Region: Peptidase_U32; pfam01136 291112007086 HMMPfam hit to PF01136, Peptidase family U32, score 9.8e-147 291112007087 Domain of unknown function (DUF1508); Region: DUF1508; pfam07411 291112007088 Domain of unknown function (DUF1508); Region: DUF1508; pfam07411 291112007089 HMMPfam hit to PF07411, Domain of unknown function (DUF1508), score 1.1e-09 291112007090 HMMPfam hit to PF07411, Domain of unknown function (DUF1508), score 2.1e-20 291112007091 DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710 291112007092 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112007093 active site 291112007094 phosphorylation site [posttranslational modification] 291112007095 intermolecular recognition site; other site 291112007096 dimerization interface [polypeptide binding]; other site 291112007097 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112007098 DNA binding site [nucleotide binding] 291112007099 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 6.4e-20 291112007100 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.6e-31 291112007101 HMMSmart hit to SM00448, no description, score 6.5e-40 291112007102 signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549 291112007103 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 291112007104 dimerization interface [polypeptide binding]; other site 291112007105 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112007106 dimer interface [polypeptide binding]; other site 291112007107 phosphorylation site [posttranslational modification] 291112007108 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112007109 ATP binding site [chemical binding]; other site 291112007110 Mg2+ binding site [ion binding]; other site 291112007111 G-X-G motif; other site 291112007112 HMMSmart hit to SM00387, no description, score 1.2e-25 291112007113 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.7e-28 291112007114 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 6.2e-16; HMMSmart hit to SM00388, no description, score 5e-14 291112007115 HMMSmart hit to SM00304, no description, score 1.6e-12 291112007116 HMMPfam hit to PF00672, HAMP domain, score 1.5e-18 291112007117 2 probable transmembrane helices predicted for PAT3715 by TMHMM2.0 at aa 10-32 and 158-180 291112007118 multidrug efflux system subunit MdtC; Provisional; Region: PRK10614 291112007119 Protein export membrane protein; Region: SecD_SecF; cl14618 291112007120 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 291112007121 10 probable transmembrane helices predicted for PAT3714 by TMHMM2.0 at aa 12-34, 336-353, 360-382, 431-450, 463-485, 528-547, 853-875, 895-917, 949-971 and 986-1008 291112007122 multidrug efflux system subunit MdtB; Provisional; Region: PRK10503 291112007123 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 291112007124 11 probable transmembrane helices predicted for PAT3713 by TMHMM2.0 at aa 15-37, 345-367, 372-394, 440-462, 472-491, 536-558, 862-884, 891-913, 918-937, 968-990 and 1000-1022 291112007125 multidrug efflux system subunit MdtA; Provisional; Region: PRK11556 291112007126 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112007127 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112007128 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.1e-21 291112007129 1 probable transmembrane helix predicted for PAT3712 by TMHMM2.0 at aa 7-29 291112007130 Homeodomain-like domain; Region: HTH_23; pfam13384 291112007131 Winged helix-turn helix; Region: HTH_29; pfam13551 291112007132 Winged helix-turn helix; Region: HTH_33; pfam13592 291112007133 DDE superfamily endonuclease; Region: DDE_3; pfam13358 291112007134 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335 291112007135 nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base; Region: nuc_hydro_CeIAG; cd02649 291112007136 active site 291112007137 HMMPfam hit to PF01156, Inosine-uridine preferring nucleoside hy, score 1.2e-55 291112007138 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 291112007139 active site 291112007140 HMMPfam hit to PF00962, Adenosine/AMP deaminase, score 8e-06 291112007141 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 291112007142 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 291112007143 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 291112007144 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 291112007145 ligand binding site [chemical binding]; other site 291112007146 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 4e-11 291112007147 Protein of unknown function (DUF2633); Region: DUF2633; pfam11119 291112007148 1 probable transmembrane helix predicted for PAT3705 by TMHMM2.0 at aa 12-34 291112007149 exopolyphosphatase; Provisional; Region: PRK10854 291112007150 Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541 291112007151 HMMPfam hit to PF02541, Ppx/GppA phosphatase family, score 9.3e-124 291112007152 polyphosphate kinase; Provisional; Region: PRK05443 291112007153 Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089 291112007154 Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503 291112007155 Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164 291112007156 domain interface [polypeptide binding]; other site 291112007157 active site 291112007158 catalytic site [active] 291112007159 Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167 291112007160 domain interface [polypeptide binding]; other site 291112007161 active site 291112007162 catalytic site [active] 291112007163 HMMPfam hit to PF02503, Polyphosphate kinase, score 0 291112007164 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 291112007165 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 291112007166 Coenzyme A binding pocket [chemical binding]; other site 291112007167 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.6e-14 291112007168 phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647 291112007169 Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645 291112007170 active site 291112007171 substrate binding site [chemical binding]; other site 291112007172 cosubstrate binding site; other site 291112007173 catalytic site [active] 291112007174 HMMPfam hit to PF00551, Formyl transferase, score 1.6e-88 291112007175 phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385 291112007176 PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196 291112007177 dimerization interface [polypeptide binding]; other site 291112007178 putative ATP binding site [chemical binding]; other site 291112007179 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 1.9e-48 291112007180 HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 7.3e-74 291112007181 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112007182 active site 291112007183 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 2.4e-12 291112007184 uracil transporter; Provisional; Region: PRK10720 291112007185 HMMPfam hit to PF00860, Permease family, score 1.8e-136 291112007186 12 probable transmembrane helices predicted for PAT3698 by TMHMM2.0 at aa 20-39, 44-61, 68-85, 89-108, 115-134, 154-176, 178-200, 225-247, 304-326, 331-353, 365-387 and 392-411 291112007187 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486 291112007188 Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296 291112007189 NAD binding site [chemical binding]; other site 291112007190 sugar binding site [chemical binding]; other site 291112007191 divalent metal binding site [ion binding]; other site 291112007192 tetramer (dimer of dimers) interface [polypeptide binding]; other site 291112007193 dimer interface [polypeptide binding]; other site 291112007194 HMMPfam hit to PF02056, Family 4 glycosyl hydrolase, score 1.1e-124 291112007195 PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215 291112007196 methionine cluster; other site 291112007197 active site 291112007198 phosphorylation site [posttranslational modification] 291112007199 metal binding site [ion binding]; metal-binding site 291112007200 HMMPfam hit to PF02255, PTS system, Lactose/Cellobiose specific IIA, score 1.9e-33 291112007201 Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455 291112007202 cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592 291112007203 10 probable transmembrane helices predicted for PAT3693 by TMHMM2.0 at aa 34-56, 81-103, 110-129, 134-156, 177-199, 219-241, 248-270, 285-307, 331-353 and 394-413 291112007204 HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 2.2e-79 291112007205 PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564 291112007206 active site 291112007207 P-loop; other site 291112007208 phosphorylation site [posttranslational modification] 291112007209 HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 1.2e-37 291112007210 ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593 291112007211 DNA replication initiation factor; Provisional; Region: PRK08084 291112007212 HMMPfam hit to PF00308, Bacterial dnaA protein, score 1.2e-06 291112007213 Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034 291112007214 ArsC family; Region: ArsC; pfam03960 291112007215 catalytic residues [active] 291112007216 HMMPfam hit to PF03960, ArsC family, score 6.9e-50 291112007217 Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783 291112007218 Peptidase family M48; Region: Peptidase_M48; cl12018 291112007219 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 291112007220 TPR motif; other site 291112007221 binding surface 291112007222 HMMPfam hit to PF01435, Peptidase family M48, score 4.7e-28 291112007223 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 291112007224 Domain of unknown function DUF20; Region: UPF0118; pfam01594 291112007225 HMMPfam hit to PF01594, Domain of unknown function DUF20, score 2.1e-88 291112007226 7 probable transmembrane helices predicted for PAT3688 by TMHMM2.0 at aa 21-52, 67-89, 153-175, 220-242, 247-269, 279-301 and 310-332 291112007227 Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450 291112007228 Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017 291112007229 catalytic triad [active] 291112007230 HMMPfam hit to PF08534, Redoxin, score 8.6e-23 291112007231 HMMPfam hit to PF00578, AhpC/TSA family, score 1.8e-09 291112007232 glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589 291112007233 ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893 291112007234 ACT domain; Region: ACT_5; pfam13710 291112007235 HMMPfam hit to PF01842, ACT domain, score 0.014 291112007236 HMMPfam hit to PF01842, ACT domain, score 4.6e-05 291112007237 Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950 291112007238 dihydrodipicolinate synthase; Region: dapA; TIGR00674 291112007239 dimer interface [polypeptide binding]; other site 291112007240 active site 291112007241 catalytic residue [active] 291112007242 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 2e-152 291112007243 lipoprotein; Provisional; Region: PRK11679 291112007244 NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804 291112007245 HMMPfam hit to PF06804, NlpB/DapX lipoprotein, score 3.4e-141 291112007246 phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362 291112007247 bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415 291112007248 ATP binding site [chemical binding]; other site 291112007249 active site 291112007250 substrate binding site [chemical binding]; other site 291112007251 HMMPfam hit to PF01259, SAICAR synthetase, score 9.5e-114 291112007252 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 291112007253 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112007254 Walker A/P-loop; other site 291112007255 ATP binding site [chemical binding]; other site 291112007256 Q-loop/lid; other site 291112007257 ABC transporter signature motif; other site 291112007258 Walker B; other site 291112007259 D-loop; other site 291112007260 H-loop/switch region; other site 291112007261 5 probable transmembrane helices predicted for PAT3681 by TMHMM2.0 at aa 26-48, 63-85, 142-164, 168-190 and 250-272 291112007262 HMMSmart hit to SM00382, no description, score 9.7e-13 291112007263 HMMPfam hit to PF00005, ABC transporter, score 3.6e-44 291112007264 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 291112007265 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112007266 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112007267 Walker A/P-loop; other site 291112007268 ATP binding site [chemical binding]; other site 291112007269 Q-loop/lid; other site 291112007270 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112007271 ABC transporter signature motif; other site 291112007272 ABC transporter signature motif; other site 291112007273 Walker B; other site 291112007274 Walker B; other site 291112007275 D-loop; other site 291112007276 D-loop; other site 291112007277 H-loop/switch region; other site 291112007278 6 probable transmembrane helices predicted for PAT3680 by TMHMM2.0 at aa 26-48, 63-85, 138-160, 165-182, 245-267 and 277-299 291112007279 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.1e-10 291112007280 HMMSmart hit to SM00382, no description, score 6.8e-08 291112007281 HMMPfam hit to PF00005, ABC transporter, score 3.9e-37 291112007282 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112007283 PGAP1-like protein; Region: PGAP1; pfam07819 291112007284 Phosphopantetheine attachment site; Region: PP-binding; cl09936 291112007285 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 8.5e-07 291112007286 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 291112007287 FtsX-like permease family; Region: FtsX; pfam02687 291112007288 HMMPfam hit to PF02687, Predicted permease, score 8.9e-43 291112007289 4 probable transmembrane helices predicted for PAT3676 by TMHMM2.0 at aa 35-57, 289-311, 332-354 and 369-391 291112007290 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 291112007291 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 291112007292 Walker A/P-loop; other site 291112007293 ATP binding site [chemical binding]; other site 291112007294 Q-loop/lid; other site 291112007295 ABC transporter signature motif; other site 291112007296 Walker B; other site 291112007297 D-loop; other site 291112007298 H-loop/switch region; other site 291112007299 HMMSmart hit to SM00382, no description, score 1.9e-10 291112007300 HMMPfam hit to PF00005, ABC transporter, score 3e-46 291112007301 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 291112007302 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112007303 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112007304 HMMPfam hit to PF00529, HlyD family secretion protein, score 0.0045 291112007305 1 probable transmembrane helix predicted for PAT3674 by TMHMM2.0 at aa 7-26 291112007306 Condensation domain; Region: Condensation; pfam00668 291112007307 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112007308 AMP-binding enzyme; Region: AMP-binding; pfam00501 291112007309 acyl-activating enzyme (AAE) consensus motif; other site 291112007310 active site 291112007311 AMP binding site [chemical binding]; other site 291112007312 CoA binding site [chemical binding]; other site 291112007313 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112007314 Condensation domain; Region: Condensation; pfam00668 291112007315 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112007316 HMMPfam hit to PF00668, Condensation domain, score 2.2e-11 291112007317 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.1e-77 291112007318 2 probable transmembrane helices predicted for PAT3672 by TMHMM2.0 at aa 13-35 and 45-64 291112007319 putative TOMM peptide; Region: TOMM_nitrile_2; TIGR04351 291112007320 1 probable transmembrane helix predicted for PAT3671 by TMHMM2.0 at aa 7-26 291112007321 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112007322 peptide modification radical SAM enzyme, YydG family; Region: rSAM_yydG; TIGR04078 291112007323 FeS/SAM binding site; other site 291112007324 HMMPfam hit to PF04055, Radical SAM superfamily, score 0.01 291112007325 Protein of unknown function (DUF441); Region: DUF441; pfam04284 291112007326 HMMPfam hit to PF04284, Protein of unknown function (DUF441), score 2.3e-68 291112007327 4 probable transmembrane helices predicted for PAT3667 by TMHMM2.0 at aa 30-52, 72-91, 98-120 and 135-169 291112007328 Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444 291112007329 Domain of unknown function (DUF1726); Region: DUF1726; pfam08351 291112007330 Helicase; Region: Helicase_RecD; pfam05127 291112007331 GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718 291112007332 Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725 291112007333 HMMPfam hit to PF05127, Putative ATPase (DUF699), score 4.3e-35 291112007334 Uncharacterized protein family (UPF0370); Region: UPF0370; pfam13980 291112007335 1 probable transmembrane helix predicted for PAT3665 by TMHMM2.0 at aa 4-23 291112007336 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876 291112007337 D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557 291112007338 HMMPfam hit to PF02557, D-alanyl-D-alanine carboxypeptidase, score 2.2e-77 291112007339 succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009 291112007340 M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891 291112007341 metal binding site [ion binding]; metal-binding site 291112007342 dimer interface [polypeptide binding]; other site 291112007343 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 7.7e-55 291112007344 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 2e-34 291112007345 Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035 291112007346 ArsC family; Region: ArsC; pfam03960 291112007347 putative catalytic residues [active] 291112007348 HMMPfam hit to PF03960, ArsC family, score 1.7e-41 291112007349 transcriptional regulator NarP; Provisional; Region: PRK10403 291112007350 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112007351 active site 291112007352 phosphorylation site [posttranslational modification] 291112007353 intermolecular recognition site; other site 291112007354 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112007355 DNA binding residues [nucleotide binding] 291112007356 dimerization interface [polypeptide binding]; other site 291112007357 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 8.9e-24; HMMSmart hit to SM00421, no description, score 9.7e-23 291112007358 HMMPfam hit to PF00072, Response regulator receiver domain, score 2e-37 291112007359 HMMSmart hit to SM00448, no description, score 5.1e-27 291112007360 bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232 291112007361 Malic enzyme, N-terminal domain; Region: malic; pfam00390 291112007362 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 291112007363 putative NAD(P) binding site [chemical binding]; other site 291112007364 Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280 291112007365 HMMPfam hit to PF00390, Malic enzyme, N-terminal domain, score 3.8e-78 291112007366 HMMPfam hit to PF03949, Malic enzyme, NAD binding domain, score 9.4e-128 291112007367 HMMPfam hit to PF01515, Phosphate acetyl/butaryl transferase, score 3.1e-112 291112007368 Protein of unknown function, DUF399; Region: DUF399; pfam04187 291112007369 1 probable transmembrane helix predicted for PAT3659 by TMHMM2.0 at aa 12-34 291112007370 HMMPfam hit to PF04187, Protein of unknown function, DUF399, score 1.3e-49 291112007371 Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810 291112007372 Gram-negative bacterial tonB protein; Region: TonB; pfam03544 291112007373 Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770 291112007374 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 291112007375 HMMPfam hit to PF02897, Prolyl oligopeptidase, N-terminal beta, score 1.6e-101 291112007376 HMMPfam hit to PF00326, Prolyl oligopeptidase family, score 2.7e-97 291112007377 TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786 291112007378 Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244 291112007379 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.6e-14 291112007380 HMMPfam hit to PF00593, TonB dependent receptor, score 8.5e-29 291112007381 exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286 291112007382 ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489 291112007383 generic binding surface II; other site 291112007384 generic binding surface I; other site 291112007385 HMMPfam hit to PF02601, Exonuclease VII, large subunit, score 5.1e-76 291112007386 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 3e-11 291112007387 inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567 291112007388 TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186 291112007389 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601 291112007390 IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381 291112007391 active site 291112007392 HMMPfam hit to PF00478, IMP dehydrogenase / GMP reductase domain, score 4.1e-242 291112007393 HMMPfam hit to PF00571, CBS domain pair, score 4.3e-25 291112007394 HMMSmart hit to SM00116, no description, score 3.7e-11 291112007395 HMMSmart hit to SM00116, no description, score 3.1e-07 291112007396 GMP synthase; Reviewed; Region: guaA; PRK00074 291112007397 Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742 291112007398 AMP/PPi binding site [chemical binding]; other site 291112007399 candidate oxyanion hole; other site 291112007400 catalytic triad [active] 291112007401 potential glutamine specificity residues [chemical binding]; other site 291112007402 The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997 291112007403 ATP Binding subdomain [chemical binding]; other site 291112007404 Ligand Binding sites [chemical binding]; other site 291112007405 Dimerization subdomain; other site 291112007406 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 2.2e-52 291112007407 HMMPfam hit to PF00958, GMP synthase C terminal domain, score 3.4e-59 291112007408 Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681 291112007409 1 probable transmembrane helix predicted for PAT3651 by TMHMM2.0 at aa 61-83 291112007410 Predicted membrane protein (DUF2335); Region: DUF2335; pfam10097 291112007411 23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088 291112007412 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112007413 S-adenosylmethionine binding site [chemical binding]; other site 291112007414 HMMPfam hit to PF08241, Methyltransferase domain, score 2.7e-07 291112007415 HMMPfam hit to PF08242, Methyltransferase domain, score 0.00019 291112007416 hypothetical protein; Provisional; Region: PRK11469 291112007417 Domain of unknown function DUF; Region: DUF204; pfam02659 291112007418 Domain of unknown function DUF; Region: DUF204; pfam02659 291112007419 6 probable transmembrane helices predicted for PAT3648 by TMHMM2.0 at aa 4-23, 36-58, 68-85, 106-128, 133-155 and 168-190 291112007420 HMMPfam hit to PF02659, Domain of unknown function DUF, score 4e-24 291112007421 HMMPfam hit to PF02659, Domain of unknown function DUF, score 5.5e-30 291112007422 hypothetical protein; Provisional; Region: PRK02913 291112007423 HMMPfam hit to PF06173, Protein of unknown function (DUF986), score 3.4e-63 291112007424 3 probable transmembrane helices predicted for PAT3647 by TMHMM2.0 at aa 6-28, 48-65 and 69-87 291112007425 PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103 291112007426 HMMPfam hit to PF03613, PTS system mannose/fructose/sorbose family I, score 2.3e-177 291112007427 3 probable transmembrane helices predicted for PAT3646 by TMHMM2.0 at aa 106-128, 148-170 and 264-286 291112007428 PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065 291112007429 7 probable transmembrane helices predicted for PAT3645 by TMHMM2.0 at aa 5-24, 33-55, 70-89, 96-118, 138-160, 180-202 and 217-239 291112007430 HMMPfam hit to PF03609, PTS system sorbose-specific iic component, score 8.7e-144 291112007431 PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088 291112007432 PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006 291112007433 active pocket/dimerization site; other site 291112007434 active site 291112007435 phosphorylation site [posttranslational modification] 291112007436 PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001 291112007437 active site 291112007438 phosphorylation site [posttranslational modification] 291112007439 HMMPfam hit to PF03830, PTS system sorbose subfamily IIB componen, score 2.1e-92 291112007440 HMMPfam hit to PF03610, PTS system fructose IIA component, score 1.8e-51 291112007441 L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720 291112007442 Serine dehydratase beta chain; Region: SDH_beta; pfam03315 291112007443 Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313 291112007444 HMMPfam hit to PF03313, Serine dehydratase alpha chain, score 5.7e-194 291112007445 HMMPfam hit to PF03315, Serine dehydratase beta chain, score 4.3e-97 291112007446 Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426 291112007447 putative active site [active] 291112007448 putative CoA binding site [chemical binding]; other site 291112007449 nudix motif; other site 291112007450 metal binding site [ion binding]; metal-binding site 291112007451 HMMPfam hit to PF00293, NUDIX domain, score 5.4e-15 291112007452 aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465 291112007453 Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715 291112007454 chorismate binding enzyme; Region: Chorismate_bind; cl10555 291112007455 HMMPfam hit to PF00425, chorismate binding enzyme, score 9.3e-126 291112007456 HMMPfam hit to PF04715, Anthranilate synthase component I, N, score 1.7e-23 291112007457 hypothetical protein; Provisional; Region: PRK05114 291112007458 HMMPfam hit to PF03701, Uncharacterised protein family (UPF0181), score 3e-29 291112007459 hypothetical protein; Provisional; Region: PRK13680 291112007460 1 probable transmembrane helix predicted for PAT3638 by TMHMM2.0 at aa 7-29 291112007461 proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249 291112007462 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.1e-28 291112007463 DNA polymerase III subunit theta; Reviewed; Region: PRK10969 291112007464 HMMPfam hit to PF06440, DNA polymerase III, theta subunit, score 2.5e-48 291112007465 1 probable transmembrane helix predicted for PAT3635 by TMHMM2.0 at aa 13-35 291112007466 nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055 291112007467 Ferritin-like domain; Region: Ferritin; pfam00210 291112007468 ferroxidase diiron center [ion binding]; other site 291112007469 HMMPfam hit to PF00210, Ferritin-like domain, score 9.7e-46 291112007470 Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only]; Region: CopC; COG2372 291112007471 HMMPfam hit to PF04234, Copper resistance protein CopC, score 1.4e-38 291112007472 1 probable transmembrane helix predicted for PAT3633 by TMHMM2.0 at aa 13-30 291112007473 Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276 291112007474 HMMPfam hit to PF05425, Copper resistance protein D, score 1.1e-55 291112007475 8 probable transmembrane helices predicted for PAT3632 by TMHMM2.0 at aa 15-37, 44-66, 94-111, 118-140, 155-177, 198-220, 235-257 and 270-292 291112007476 Protein of unknown function (DUF2511); Region: DUF2511; pfam10709 291112007477 1 probable transmembrane helix predicted for PAT3631 by TMHMM2.0 at aa 20-37 291112007478 Protein of unknown function (DUF1480); Region: DUF1480; pfam07351 291112007479 HMMPfam hit to PF07351, Protein of unknown function (DUF1480), score 2e-37 291112007480 GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956 291112007481 GAF domain; Region: GAF_2; pfam13185 291112007482 HMMPfam hit to PF01590, GAF domain, score 1.5e-06 291112007483 HMMSmart hit to SM00065, no description, score 1.1e-06 291112007484 ProP expression regulator; Provisional; Region: PRK04950 291112007485 ProQ/FINO family; Region: ProQ; pfam04352 291112007486 putative RNA binding sites [nucleotide binding]; other site 291112007487 HMMPfam hit to PF04352, ProQ activator of osmoprotectant transporter, score 1.3e-78 291112007488 carboxy-terminal protease; Provisional; Region: PRK11186 291112007489 PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988 291112007490 protein binding site [polypeptide binding]; other site 291112007491 C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560 291112007492 Catalytic dyad [active] 291112007493 C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818 291112007494 1 probable transmembrane helix predicted for PAT3627 by TMHMM2.0 at aa 7-29 291112007495 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 2.1e-17 291112007496 HMMSmart hit to SM00228, no description, score 1.3e-08 291112007497 HMMSmart hit to SM00245, no description, score 3e-77 291112007498 HMMPfam hit to PF03572, Peptidase family S41, score 3e-66 291112007499 heat shock protein HtpX; Provisional; Region: PRK05457 291112007500 HMMPfam hit to PF06509, HtpX N-terminus, score 1.8e-51 291112007501 4 probable transmembrane helices predicted for PAT3626 by TMHMM2.0 at aa 5-27, 32-54, 157-179 and 194-216 291112007502 HMMPfam hit to PF01435, Peptidase family M48, score 1.3e-44 291112007503 Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823 291112007504 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 291112007505 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 7.8e-107 291112007506 9 probable transmembrane helices predicted for PAT3625 by TMHMM2.0 at aa 5-20, 33-51, 71-93, 105-127, 180-202, 232-254, 264-286, 369-391 and 395-417 291112007507 inner membrane protein; Provisional; Region: PRK11648 291112007508 3 probable transmembrane helices predicted for PAT3624 by TMHMM2.0 at aa 68-90, 105-127 and 150-172 291112007509 HMMPfam hit to PF04307, Predicted membrane-bound metal-dependent hyd, score 5.9e-33 291112007510 YniB-like protein; Region: YniB; pfam14002 291112007511 3 probable transmembrane helices predicted for PAT3622 by TMHMM2.0 at aa 15-37, 81-103 and 153-175 291112007512 Fructosamine kinase; Region: Fructosamin_kin; pfam03881 291112007513 HMMPfam hit to PF03881, Fructosamine kinase, score 7.3e-155 291112007514 HMMPfam hit to PF01636, Phosphotransferase enzyme family, score 8.8e-27 291112007515 ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108 291112007516 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112007517 ABC-ATPase subunit interface; other site 291112007518 dimer interface [polypeptide binding]; other site 291112007519 putative PBP binding regions; other site 291112007520 8 probable transmembrane helices predicted for PAT3620 by TMHMM2.0 at aa 21-43, 58-80, 97-114, 137-154, 171-193, 197-218, 225-244 and 254-276 291112007521 HMMPfam hit to PF00950, ABC 3 transport family, score 7.3e-135 291112007522 ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108 291112007523 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112007524 ABC-ATPase subunit interface; other site 291112007525 dimer interface [polypeptide binding]; other site 291112007526 putative PBP binding regions; other site 291112007527 7 probable transmembrane helices predicted for PAT3619 by TMHMM2.0 at aa 13-35, 50-72, 93-115, 135-157, 178-206, 221-243 and 248-267 291112007528 HMMPfam hit to PF00950, ABC 3 transport family, score 2.4e-123 291112007529 HMMPfam hit to PF01032, FecCD transport family, score 0.00047 291112007530 manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056 291112007531 ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235 291112007532 HMMSmart hit to SM00382, no description, score 3.9e-11 291112007533 HMMPfam hit to PF00005, ABC transporter, score 5.6e-48 291112007534 ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803 291112007535 Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137 291112007536 metal binding site [ion binding]; metal-binding site 291112007537 HMMPfam hit to PF01297, Periplasmic solute binding protein family, score 5.5e-137 291112007538 1 probable transmembrane helix predicted for PAT3617 by TMHMM2.0 at aa 7-29 291112007539 lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470 291112007540 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 291112007541 N-acetyl-D-glucosamine binding site [chemical binding]; other site 291112007542 catalytic residue [active] 291112007543 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 8.5e-31 291112007544 threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413 291112007545 TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667 291112007546 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973 291112007547 Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771 291112007548 active site 291112007549 dimer interface [polypeptide binding]; other site 291112007550 motif 1; other site 291112007551 motif 2; other site 291112007552 motif 3; other site 291112007553 ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860 291112007554 anticodon binding site; other site 291112007555 HMMPfam hit to PF02824, TGS domain, score 1.3e-14 291112007556 HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase se, score 1.9e-23 291112007557 HMMPfam hit to PF00587, tRNA synthetase class II core domain (, score 2.7e-63 291112007558 HMMPfam hit to PF03129, Anticodon binding domain, score 3.9e-31 291112007559 Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198 291112007560 translation initiation factor IF-3; Reviewed; Region: infC; PRK00028 291112007561 Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707 291112007562 HMMPfam hit to PF05198, Translation initiation factor IF-3, N-termin, score 2.3e-08 291112007563 HMMPfam hit to PF00707, Translation initiation factor IF-3, C-termin, score 2.9e-53 291112007564 50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172 291112007565 HMMPfam hit to PF01632, Ribosomal protein L35, score 2.5e-34 291112007566 Ribosomal protein L20; Region: Ribosomal_L20; cd07026 291112007567 23S rRNA binding site [nucleotide binding]; other site 291112007568 L21 binding site [polypeptide binding]; other site 291112007569 L13 binding site [polypeptide binding]; other site 291112007570 HMMPfam hit to PF00453, Ribosomal protein L20, score 3.9e-69 291112007571 phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488 291112007572 Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912 291112007573 Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496 291112007574 dimer interface [polypeptide binding]; other site 291112007575 motif 1; other site 291112007576 active site 291112007577 motif 2; other site 291112007578 motif 3; other site 291112007579 HMMPfam hit to PF02912, Aminoacyl tRNA synthetase class II, N, score 1.1e-31 291112007580 HMMPfam hit to PF01409, tRNA synthetases class II core domain, score 3.2e-166 291112007581 phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629 291112007582 tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796 291112007583 putative tRNA-binding site [nucleotide binding]; other site 291112007584 B3/4 domain; Region: B3_4; pfam03483 291112007585 tRNA synthetase B5 domain; Region: B5; smart00874 291112007586 Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an...; Region: PheRS_beta_core; cd00769 291112007587 dimer interface [polypeptide binding]; other site 291112007588 motif 1; other site 291112007589 motif 3; other site 291112007590 motif 2; other site 291112007591 Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147 291112007592 HMMPfam hit to PF01588, Putative tRNA binding domain, score 2.5e-43 291112007593 HMMPfam hit to PF03483, B3/4 domain, score 2.1e-106 291112007594 HMMPfam hit to PF03484, tRNA synthetase B5 domain, score 1.2e-33 291112007595 HMMPfam hit to PF03147, Ferredoxin-fold anticodon binding domain, score 6.2e-42 291112007596 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 291112007597 IHF dimer interface [polypeptide binding]; other site 291112007598 IHF - DNA interface [nucleotide binding]; other site 291112007599 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 2.2e-45; HMMSmart hit to SM00411, no description, score 3.1e-42 291112007600 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 291112007601 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112007602 ABC-ATPase subunit interface; other site 291112007603 dimer interface [polypeptide binding]; other site 291112007604 putative PBP binding regions; other site 291112007605 9 probable transmembrane helices predicted for PAT3608 by TMHMM2.0 at aa 21-43, 63-82, 95-114, 119-141, 153-175, 195-212, 244-266, 281-303 and 310-329 291112007606 HMMPfam hit to PF01032, FecCD transport family, score 8e-105 291112007607 vitamin B12-transporter ATPase; Provisional; Region: PRK03695 291112007608 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 291112007609 Walker A/P-loop; other site 291112007610 ATP binding site [chemical binding]; other site 291112007611 Q-loop/lid; other site 291112007612 ABC transporter signature motif; other site 291112007613 Walker B; other site 291112007614 D-loop; other site 291112007615 H-loop/switch region; other site 291112007616 HMMSmart hit to SM00382, no description, score 1.2e-06 291112007617 HMMPfam hit to PF00005, ABC transporter, score 1e-34 291112007618 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 291112007619 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 291112007620 inhibitor-cofactor binding pocket; inhibition site 291112007621 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112007622 catalytic residue [active] 291112007623 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 4e-167 291112007624 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.00049 291112007625 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714 291112007626 Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187 291112007627 Ligand binding site; other site 291112007628 Putative Catalytic site; other site 291112007629 DXD motif; other site 291112007630 HMMPfam hit to PF00535, Glycosyl transferase family, score 2e-35 291112007631 2 probable transmembrane helices predicted for PAT3605 by TMHMM2.0 at aa 234-256 and 269-291 291112007632 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125 291112007633 Formyltransferase, catalytic core domain; Region: FMT_core; cl00395 291112007634 active site 291112007635 substrate binding site [chemical binding]; other site 291112007636 cosubstrate binding site; other site 291112007637 catalytic site [active] 291112007638 C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702 291112007639 active site 291112007640 hexamer interface [polypeptide binding]; other site 291112007641 Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257 291112007642 NAD binding site [chemical binding]; other site 291112007643 substrate binding site [chemical binding]; other site 291112007644 active site 291112007645 HMMPfam hit to PF00551, Formyl transferase, score 9.2e-20 291112007646 HMMPfam hit to PF02911, Formyl transferase, C-terminal domain, score 3.6e-25 291112007647 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fa, score 2e-47 291112007648 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394 291112007649 Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939 291112007650 putative active site [active] 291112007651 putative catalytic site [active] 291112007652 putative Zn binding site [ion binding]; other site 291112007653 HMMPfam hit to PF01522, Polysaccharide deacetylase, score 1.4e-06 291112007654 4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279 291112007655 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 291112007656 HMMPfam hit to PF02366, Dolichyl-phosphate-mannose-protein mannosylt, score 1.7e-43 291112007657 11 probable transmembrane helices predicted for PAT3602 by TMHMM2.0 at aa 9-31, 85-107, 114-136, 179-201, 208-230, 262-284, 296-313, 318-337, 350-372, 387-404 and 411-430 291112007658 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051 291112007659 3 probable transmembrane helices predicted for PAT3601 by TMHMM2.0 at aa 32-54, 59-81 and 86-105 291112007660 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971 291112007661 4 probable transmembrane helices predicted for PAT3600 by TMHMM2.0 at aa 7-29, 49-71, 78-100 and 104-123 291112007662 NlpC/P60 family; Region: NLPC_P60; pfam00877 291112007663 HMMPfam hit to PF00877, NlpC/P60 family, score 4.3e-48 291112007664 Peptidases of the G1 family and homologs that might lack peptidase activity; Region: Peptidase_G1_like; cl03371 291112007665 Flagellar protein FlhE; Region: FlhE; pfam06366 291112007666 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 291112007667 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 291112007668 Walker A/P-loop; other site 291112007669 ATP binding site [chemical binding]; other site 291112007670 Q-loop/lid; other site 291112007671 ABC transporter signature motif; other site 291112007672 Walker B; other site 291112007673 D-loop; other site 291112007674 H-loop/switch region; other site 291112007675 HMMSmart hit to SM00382, no description, score 8.6e-13 291112007676 HMMPfam hit to PF00005, ABC transporter, score 4.1e-59 291112007677 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 291112007678 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 291112007679 FtsX-like permease family; Region: FtsX; pfam02687 291112007680 4 probable transmembrane helices predicted for PAT3593 by TMHMM2.0 at aa 29-51, 270-292, 326-348 and 355-377 291112007681 HMMPfam hit to PF02687, Predicted permease, score 1.1e-40 291112007682 Outer membrane efflux protein; Region: OEP; pfam02321 291112007683 Outer membrane efflux protein; Region: OEP; pfam02321 291112007684 1 probable transmembrane helix predicted for PAT3592 by TMHMM2.0 at aa 5-27 291112007685 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.1e-07 291112007686 HMMPfam hit to PF02321, Outer membrane efflux protein, score 1.1e-06 291112007687 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112007688 Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999 291112007689 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112007690 1 probable transmembrane helix predicted for PAT3591 by TMHMM2.0 at aa 12-34 291112007691 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.6e-07 291112007692 1 probable transmembrane helix predicted for PAT3590 by TMHMM2.0 at aa 7-29 291112007693 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 291112007694 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112007695 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 6.2e-12 291112007696 HMMSmart hit to SM00342, no description, score 1.3e-36 291112007697 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 7.1e-09 291112007698 4 probable transmembrane helices predicted for PAT3587 by TMHMM2.0 at aa 12-34, 101-118, 138-160 and 175-197 291112007699 hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548 291112007700 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 291112007701 Walker A/P-loop; other site 291112007702 ATP binding site [chemical binding]; other site 291112007703 Q-loop/lid; other site 291112007704 ABC transporter signature motif; other site 291112007705 Walker B; other site 291112007706 D-loop; other site 291112007707 H-loop/switch region; other site 291112007708 HMMSmart hit to SM00382, no description, score 3.1e-15 291112007709 HMMPfam hit to PF00005, ABC transporter, score 3.8e-39 291112007710 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 291112007711 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112007712 ABC-ATPase subunit interface; other site 291112007713 dimer interface [polypeptide binding]; other site 291112007714 putative PBP binding regions; other site 291112007715 HMMPfam hit to PF01032, FecCD transport family, score 1.4e-138 291112007716 8 probable transmembrane helices predicted for PAT3585 by TMHMM2.0 at aa 7-29, 58-80, 87-109, 113-135, 148-170, 190-209, 240-262 and 307-326 291112007717 Hemin binding protein HutB. These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149 291112007718 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 291112007719 putative hemin binding site; other site 291112007720 HMMPfam hit to PF01497, Periplasmic binding protein, score 7e-43 291112007721 Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720 291112007722 Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171 291112007723 Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171 291112007724 HMMPfam hit to PF05171, Haemin-degrading family, score 6e-82 291112007725 TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785 291112007726 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 291112007727 N-terminal plug; other site 291112007728 ligand-binding site [chemical binding]; other site 291112007729 HMMPfam hit to PF00593, TonB dependent receptor, score 1.1e-19 291112007730 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.6e-28 291112007731 phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756 291112007732 DAHP synthetase I family; Region: DAHP_synth_1; pfam00793 291112007733 HMMPfam hit to PF00793, DAHP synthetase I family, score 3.5e-149 291112007734 PEP synthetase regulatory protein; Provisional; Region: PRK05339 291112007735 HMMPfam hit to PF03618, Domain of unknown function (DUF299), score 3.4e-141 291112007736 phosphoenolpyruvate synthase; Validated; Region: PRK06464 291112007737 Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326 291112007738 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 291112007739 PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 291112007740 HMMPfam hit to PF01326, Pyruvate phosphate dikinase, PEP/pyru, score 2.9e-155 291112007741 HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 6.4e-43 291112007742 HMMPfam hit to PF02896, PEP-utilising enzyme, TIM barrel doma, score 9.3e-56 291112007743 putative inner membrane protein; Provisional; Region: PRK10983 291112007744 Domain of unknown function DUF20; Region: UPF0118; pfam01594 291112007745 HMMPfam hit to PF01594, Domain of unknown function DUF20, score 1.7e-48 291112007746 8 probable transmembrane helices predicted for PAT3578 by TMHMM2.0 at aa 13-30, 34-52, 64-86, 161-180, 215-237, 247-269, 282-301 and 316-338 291112007747 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 291112007748 FAD binding domain; Region: FAD_binding_4; pfam01565 291112007749 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 291112007750 HMMPfam hit to PF01565, FAD binding domain, score 2.4e-48 291112007751 HMMPfam hit to PF02913, FAD linked oxidases, C-terminal domain, score 6.1e-69 291112007752 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 291112007753 CoenzymeA binding site [chemical binding]; other site 291112007754 subunit interaction site [polypeptide binding]; other site 291112007755 PHB binding site; other site 291112007756 HMMPfam hit to PF03061, Thioesterase superfamily, score 4.3e-18 291112007757 Homeodomain-like domain; Region: HTH_23; pfam13384 291112007758 Winged helix-turn helix; Region: HTH_29; pfam13551 291112007759 Winged helix-turn helix; Region: HTH_33; pfam13592 291112007760 DDE superfamily endonuclease; Region: DDE_3; pfam13358 291112007761 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335 291112007762 iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504 291112007763 HMMPfam hit to PF01521, Iron-sulphur cluster biosynthesis, score 2.5e-31 291112007764 putative ABC transporter; Region: ycf24; CHL00085 291112007765 cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814 291112007766 HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051), score 5.8e-139 291112007767 cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580 291112007768 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217 291112007769 Walker A/P-loop; other site 291112007770 ATP binding site [chemical binding]; other site 291112007771 Q-loop/lid; other site 291112007772 ABC transporter signature motif; other site 291112007773 Walker B; other site 291112007774 D-loop; other site 291112007775 H-loop/switch region; other site 291112007776 HMMSmart hit to SM00382, no description, score 1.2e-07 291112007777 HMMPfam hit to PF00005, ABC transporter, score 1.1e-27 291112007778 cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948 291112007779 FeS assembly protein SufD; Region: sufD; TIGR01981 291112007780 HMMPfam hit to PF01458, Uncharacterized protein family (UPF0051), score 4.5e-81 291112007781 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 291112007782 Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453 291112007783 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112007784 catalytic residue [active] 291112007785 HMMPfam hit to PF00266, Aminotransferase class-V, score 1e-202 291112007786 cysteine desufuration protein SufE; Provisional; Region: PRK09296 291112007787 HMMPfam hit to PF02657, Fe-S metabolism associated domain, score 5.8e-50 291112007788 L,D-transpeptidase; Provisional; Region: PRK10190 291112007789 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107 291112007790 L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734 291112007791 HMMPfam hit to PF03734, ErfK/YbiS/YcfS/YnhG, score 6.8e-63 291112007792 murein lipoprotein; Provisional; Region: PRK15396 291112007793 HMMPfam hit to PF04728, Repeated sequence found in lipoprotein LPP, score 0.013 291112007794 enoyl-CoA hydratase; Provisional; Region: PRK06142 291112007795 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 291112007796 substrate binding site [chemical binding]; other site 291112007797 oxyanion hole (OAH) forming residues; other site 291112007798 trimer interface [polypeptide binding]; other site 291112007799 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 4.5e-28 291112007800 HTH-like domain; Region: HTH_21; pfam13276 291112007801 Integrase core domain; Region: rve; pfam00665 291112007802 inositol phosphate phosphatase SopB; Provisional; Region: PRK15378 291112007803 HMMPfam hit to PF05925, Enterobacterial virulence protein IpgD, score 1.6e-194 291112007804 pyruvate kinase; Provisional; Region: PRK09206 291112007805 Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288 291112007806 domain interfaces; other site 291112007807 active site 291112007808 HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta domain, score 1.5e-25 291112007809 HMMPfam hit to PF00224, Pyruvate kinase, barrel domain, score 8e-212 291112007810 multidrug efflux protein; Reviewed; Region: PRK01766 291112007811 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131 291112007812 cation binding site [ion binding]; other site 291112007813 12 probable transmembrane helices predicted for PAT3560 by TMHMM2.0 at aa 12-34, 49-71, 91-113, 128-147, 159-181, 186-208, 241-263, 278-300, 313-335, 350-367, 387-409 and 419-441 291112007814 HMMPfam hit to PF01554, MatE, score 9.7e-53 291112007815 HMMPfam hit to PF01554, MatE, score 1.4e-39 291112007816 riboflavin synthase subunit alpha; Provisional; Region: PRK13020 291112007817 Lumazine binding domain; Region: Lum_binding; pfam00677 291112007818 Lumazine binding domain; Region: Lum_binding; pfam00677 291112007819 HMMPfam hit to PF00677, Lumazine binding domain, score 7.7e-35 291112007820 HMMPfam hit to PF00677, Lumazine binding domain, score 1.6e-39 291112007821 Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309 291112007822 cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705 291112007823 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 291112007824 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112007825 S-adenosylmethionine binding site [chemical binding]; other site 291112007826 HMMPfam hit to PF02353, Cyclopropane-fatty-acyl-phospholipid, score 3e-137 291112007827 HMMPfam hit to PF08241, Methyltransferase domain, score 9.6e-15 291112007828 HMMPfam hit to PF08242, Methyltransferase domain, score 4.4e-08 291112007829 putative transporter; Provisional; Region: PRK11043 291112007830 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112007831 putative substrate translocation pore; other site 291112007832 12 probable transmembrane helices predicted for PAT3556 by TMHMM2.0 at aa 7-29, 39-61, 73-92, 97-119, 131-153, 158-180, 209-231, 241-263, 270-289, 299-321, 334-356 and 366-385 291112007833 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 2.8e-54 291112007834 putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074 291112007835 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112007836 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 291112007837 dimerization interface [polypeptide binding]; other site 291112007838 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.5e-18 291112007839 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.1e-23 291112007840 DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703 291112007841 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 291112007842 DNA binding site [nucleotide binding] 291112007843 domain linker motif; other site 291112007844 Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275 291112007845 dimerization interface [polypeptide binding]; other site 291112007846 ligand binding site [chemical binding]; other site 291112007847 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.2e-23 291112007848 HMMSmart hit to SM00354, no description, score 1.9e-34 291112007849 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 3.9e-10 291112007850 superoxide dismutase; Provisional; Region: PRK10543 291112007851 Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081 291112007852 Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777 291112007853 HMMPfam hit to PF02777, Iron/manganese superoxide dismutases, C-term, score 1.8e-68 291112007854 HMMPfam hit to PF00081, Iron/manganese superoxide dismutases, alpha-, score 3.1e-51 291112007855 Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028 291112007856 putative GSH binding site [chemical binding]; other site 291112007857 catalytic residues [active] 291112007858 HMMPfam hit to PF00462, Glutaredoxin, score 1.3e-25 291112007859 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847 291112007860 DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134 291112007861 dimer interface [polypeptide binding]; other site 291112007862 catalytic site [active] 291112007863 putative active site [active] 291112007864 putative substrate binding site [chemical binding]; other site 291112007865 HMMSmart hit to SM00479, no description, score 2.8e-35 291112007866 HMMPfam hit to PF00929, Exonuclease, score 7.6e-38 291112007867 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 291112007868 Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233 291112007869 dimer interface [polypeptide binding]; other site 291112007870 active site 291112007871 metal binding site [ion binding]; metal-binding site 291112007872 glutathione binding site [chemical binding]; other site 291112007873 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 3.4e-43 291112007874 Predicted Fe-S protein [General function prediction only]; Region: COG3313 291112007875 HMMPfam hit to PF06945, Protein of unknown function (DUF1289), score 6.7e-24 291112007876 transcriptional regulator SlyA; Provisional; Region: PRK03573 291112007877 Winged helix DNA-binding domain; Region: HTH_27; pfam13463 291112007878 HMMSmart hit to SM00347, no description, score 2.3e-22 291112007879 HMMPfam hit to PF01047, MarR family, score 2.6e-16 291112007880 Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133 291112007881 HMMPfam hit to PF05433, Rickettsia 17 kDa surface antigen, score 3e-11 291112007882 anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585 291112007883 HMMPfam hit to PF03702, Uncharacterised protein family (UPF0075), score 2e-228 291112007884 pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679 291112007885 Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243 291112007886 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590 291112007887 HMMPfam hit to PF01243, Pyridoxamine 5'-phosphate oxidase, score 7e-29 291112007888 tyrosyl-tRNA synthetase; Validated; Region: PRK05912 291112007889 catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805 291112007890 active site 291112007891 HIGH motif; other site 291112007892 dimer interface [polypeptide binding]; other site 291112007893 KMSKS motif; other site 291112007894 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 291112007895 RNA binding surface [nucleotide binding]; other site 291112007896 HMMPfam hit to PF00579, tRNA synthetases class I (W and Y), score 5.1e-131 291112007897 HMMSmart hit to SM00363, no description, score 0.0051 291112007898 HMMPfam hit to PF01479, S4 domain, score 0.00041 291112007899 pyridoxamine kinase; Validated; Region: PRK05756 291112007900 Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173 291112007901 dimer interface [polypeptide binding]; other site 291112007902 pyridoxal binding site [chemical binding]; other site 291112007903 ATP binding site [chemical binding]; other site 291112007904 HMMPfam hit to PF08543, Phosphomethylpyrimidine kinase, score 0.00014 291112007905 glutathionine S-transferase; Provisional; Region: PRK10542 291112007906 GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057 291112007907 C-terminal domain interface [polypeptide binding]; other site 291112007908 GSH binding site (G-site) [chemical binding]; other site 291112007909 dimer interface [polypeptide binding]; other site 291112007910 C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188 291112007911 dimer interface [polypeptide binding]; other site 291112007912 N-terminal domain interface [polypeptide binding]; other site 291112007913 substrate binding pocket (H-site) [chemical binding]; other site 291112007914 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 1.8e-14 291112007915 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 2.2e-09 291112007916 Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: COG1193 291112007917 enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984 291112007918 Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372 291112007919 NAD binding site [chemical binding]; other site 291112007920 homotetramer interface [polypeptide binding]; other site 291112007921 homodimer interface [polypeptide binding]; other site 291112007922 substrate binding site [chemical binding]; other site 291112007923 active site 291112007924 antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112 291112007925 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 291112007926 Walker A/P-loop; other site 291112007927 ATP binding site [chemical binding]; other site 291112007928 Q-loop/lid; other site 291112007929 ABC transporter signature motif; other site 291112007930 Walker B; other site 291112007931 D-loop; other site 291112007932 H-loop/switch region; other site 291112007933 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 291112007934 HMMSmart hit to SM00382, no description, score 3.4e-13 291112007935 HMMPfam hit to PF00005, ABC transporter, score 1.2e-62 291112007936 antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093 291112007937 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 291112007938 Walker A/P-loop; other site 291112007939 ATP binding site [chemical binding]; other site 291112007940 Q-loop/lid; other site 291112007941 ABC transporter signature motif; other site 291112007942 Walker B; other site 291112007943 D-loop; other site 291112007944 H-loop/switch region; other site 291112007945 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 291112007946 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 4.9e-20 291112007947 HMMSmart hit to SM00382, no description, score 4.6e-07 291112007948 HMMPfam hit to PF00005, ABC transporter, score 1.2e-57 291112007949 antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111 291112007950 N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911 291112007951 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112007952 dimer interface [polypeptide binding]; other site 291112007953 conserved gate region; other site 291112007954 putative PBP binding loops; other site 291112007955 ABC-ATPase subunit interface; other site 291112007956 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.3e-34 291112007957 4 probable transmembrane helices predicted for PAT3536 by TMHMM2.0 at aa 20-42, 98-120, 141-163 and 261-283 291112007958 antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110 291112007959 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112007960 dimer interface [polypeptide binding]; other site 291112007961 conserved gate region; other site 291112007962 putative PBP binding loops; other site 291112007963 ABC-ATPase subunit interface; other site 291112007964 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 5.6e-51 291112007965 5 probable transmembrane helices predicted for PAT3535 by TMHMM2.0 at aa 9-31, 80-102, 109-131, 251-273 and 286-308 291112007966 ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166 291112007967 The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493 291112007968 peptide binding site [polypeptide binding]; other site 291112007969 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 6.2e-78 291112007970 phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608 291112007971 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112007972 Walker A motif; other site 291112007973 ATP binding site [chemical binding]; other site 291112007974 Walker B motif; other site 291112007975 arginine finger; other site 291112007976 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 291112007977 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 6.8e-05 291112007978 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.9e-125 291112007979 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00065 291112007980 HMMSmart hit to SM00382, no description, score 5e-12 291112007981 phage shock protein PspA; Provisional; Region: PRK10698 291112007982 HMMPfam hit to PF04012, PspA/IM30 family, score 1.4e-52 291112007983 phage shock protein B; Provisional; Region: pspB; PRK09458 291112007984 HMMPfam hit to PF06667, Phage shock protein B, score 9.4e-29 291112007985 1 probable transmembrane helix predicted for PAT3531 by TMHMM2.0 at aa 4-26 291112007986 DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697 291112007987 phage shock protein C; Region: phageshock_pspC; TIGR02978 291112007988 HMMPfam hit to PF04024, PspC domain, score 1.9e-25 291112007989 1 probable transmembrane helix predicted for PAT3530 by TMHMM2.0 at aa 41-63 291112007990 Predicted ATPase [General function prediction only]; Region: COG3106 291112007991 HMMPfam hit to PF04317, YcjX-like family, DUF463, score 0 291112007992 hypothetical protein; Provisional; Region: PRK05415 291112007993 Domain of unknown function (DUF697); Region: DUF697; cl12064 291112007994 HMMPfam hit to PF05128, Family of unknown function (DUF697), score 2.7e-165 291112007995 3 probable transmembrane helices predicted for PAT3527 by TMHMM2.0 at aa 71-90, 100-122 and 211-233 291112007996 1 probable transmembrane helix predicted for PAT3526 by TMHMM2.0 at aa 15-37 291112007997 DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820 291112007998 N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877 291112007999 putative aromatic amino acid binding site; other site 291112008000 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 291112008001 putative active site [active] 291112008002 heme pocket [chemical binding]; other site 291112008003 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112008004 Walker A motif; other site 291112008005 ATP binding site [chemical binding]; other site 291112008006 Walker B motif; other site 291112008007 arginine finger; other site 291112008008 HMMPfam hit to PF01842, ACT domain, score 0.0015 291112008009 HMMPfam hit to PF00989, PAS fold, score 0.00029 291112008010 HMMSmart hit to SM00091, no description, score 2.8e-09 291112008011 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 4.3e-123 291112008012 HMMSmart hit to SM00382, no description, score 1.1e-08 291112008013 Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014 291112008014 dimer interface [polypeptide binding]; other site 291112008015 catalytic triad [active] 291112008016 peroxidatic and resolving cysteines [active] 291112008017 HMMPfam hit to PF08534, Redoxin, score 7.4e-47 291112008018 HMMPfam hit to PF00578, AhpC/TSA family, score 0.0017 291112008019 oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104 291112008020 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 291112008021 peptide binding site [polypeptide binding]; other site 291112008022 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 6.9e-72 291112008023 Domain of unknown function (DUF4102); Region: DUF4102; pfam13356 291112008024 1 probable transmembrane helix predicted for PAT3522 by TMHMM2.0 at aa 25-47 291112008025 Domain of unknown function (DUF1983); Region: DUF1983; pfam09327 291112008026 Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876 291112008027 Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598 291112008028 Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833 291112008029 Cl binding site [ion binding]; other site 291112008030 oligomer interface [polypeptide binding]; other site 291112008031 HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein, score 1.5e-05 291112008032 2 probable transmembrane helices predicted for PAT3518 by TMHMM2.0 at aa 267-289 and 299-321 291112008033 tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696 291112008034 This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily; Region: Alpha_ANH_like_II; cd01993 291112008035 Ligand Binding Site [chemical binding]; other site 291112008036 HMMPfam hit to PF01171, PP-loop family, score 2e-06 291112008037 Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910 291112008038 HMMPfam hit to PF00893, Small Multidrug Resistance protein, score 4.2e-39 291112008039 4 probable transmembrane helices predicted for PAT3516 by TMHMM2.0 at aa 4-23, 30-47, 57-79 and 86-105 291112008040 Domain of unknown function (DUF333); Region: DUF333; pfam03891 291112008041 disulfide bond formation protein B; Provisional; Region: PRK01749 291112008042 4 probable transmembrane helices predicted for PAT3514 by TMHMM2.0 at aa 13-35, 45-64, 71-93 and 144-166 291112008043 HMMPfam hit to PF02600, Disulfide bond formation protein DsbB, score 2e-61 291112008044 sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547 291112008045 HMMPfam hit to PF06450, Bacterial Na+/H+ antiporter B (NhaB), score 0 291112008046 9 probable transmembrane helices predicted for PAT3513 by TMHMM2.0 at aa 28-50, 96-118, 131-153, 238-260, 299-330, 350-368, 389-411, 453-472 and 479-501 291112008047 fatty acid metabolism regulator; Provisional; Region: PRK04984 291112008048 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 291112008049 DNA-binding site [nucleotide binding]; DNA binding site 291112008050 FadR C-terminal domain; Region: FadR_C; pfam07840 291112008051 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR family, score 5.8e-25 291112008052 HMMSmart hit to SM00345, no description, score 2.4e-23 291112008053 HMMPfam hit to PF07840, FadR C-terminal domain, score 7.5e-121 291112008054 D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711 291112008055 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 291112008056 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 6.2e-105 291112008057 alanine racemase; Reviewed; Region: dadX; PRK03646 291112008058 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827 291112008059 active site 291112008060 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 291112008061 substrate binding site [chemical binding]; other site 291112008062 catalytic residues [active] 291112008063 dimer interface [polypeptide binding]; other site 291112008064 HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 2.7e-74 291112008065 HMMPfam hit to PF00842, Alanine racemase, C-terminal domain, score 7.3e-63 291112008066 Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713 291112008067 1 probable transmembrane helix predicted for PAT3509 by TMHMM2.0 at aa 7-29 291112008068 HMMPfam hit to PF06629, MltA-interacting protein MipA, score 1.7e-77 291112008069 D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020 291112008070 active site 291112008071 phosphate binding residues; other site 291112008072 catalytic residues [active] 291112008073 HMMPfam hit to PF01263, Aldose 1-epimerase, score 1.1e-34 291112008074 glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425 291112008075 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846 291112008076 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 291112008077 HMMPfam hit to PF02800, Glyceraldehyde 3-phosphate dehydrogenase, C-, score 1.4e-115 291112008078 HMMPfam hit to PF00044, Glyceraldehyde 3-phosphate dehydrogenase, NA, score 1.6e-101 291112008079 methionine sulfoxide reductase B; Provisional; Region: PRK00222 291112008080 SelR domain; Region: SelR; pfam01641 291112008081 HMMPfam hit to PF01641, SelR domain, score 5.4e-75 291112008082 Protein of unknown function (DUF1315); Region: DUF1315; pfam07023 291112008083 HMMPfam hit to PF07023, Protein of unknown function (DUF1315), score 1.5e-50 291112008084 Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011 291112008085 Isochorismatase family; Region: Isochorismatase; pfam00857 291112008086 catalytic triad [active] 291112008087 metal binding site [ion binding]; metal-binding site 291112008088 conserved cis-peptide bond; other site 291112008089 HMMPfam hit to PF00857, Isochorismatase family, score 5.6e-45 291112008090 Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963 291112008091 active site 291112008092 homodimer interface [polypeptide binding]; other site 291112008093 HMMPfam hit to PF00710, Asparaginase, score 8.3e-140 291112008094 protease 4; Provisional; Region: PRK10949 291112008095 Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018 291112008096 tandem repeat interface [polypeptide binding]; other site 291112008097 oligomer interface [polypeptide binding]; other site 291112008098 active site residues [active] 291112008099 Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019 291112008100 tandem repeat interface [polypeptide binding]; other site 291112008101 oligomer interface [polypeptide binding]; other site 291112008102 active site residues [active] 291112008103 HMMPfam hit to PF01343, Peptidase family S49, score 7e-69 291112008104 HMMPfam hit to PF01343, Peptidase family S49, score 3.2e-36 291112008105 1 probable transmembrane helix predicted for PAT3502 by TMHMM2.0 at aa 21-43 291112008106 Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135 291112008107 putative FMN binding site [chemical binding]; other site 291112008108 HMMPfam hit to PF00881, Nitroreductase family, score 1.7e-35 291112008109 selenophosphate synthetase; Provisional; Region: PRK00943 291112008110 Selenophosphate synthetase (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195 291112008111 dimerization interface [polypeptide binding]; other site 291112008112 putative ATP binding site [chemical binding]; other site 291112008113 HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 1.2e-11 291112008114 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 2.4e-22 291112008115 DNA topoisomerase III; Provisional; Region: PRK07726 291112008116 TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362 291112008117 active site 291112008118 putative interdomain interaction site [polypeptide binding]; other site 291112008119 putative metal-binding site [ion binding]; other site 291112008120 putative nucleotide binding site [chemical binding]; other site 291112008121 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186 291112008122 domain I; other site 291112008123 DNA binding groove [nucleotide binding] 291112008124 phosphate binding site [ion binding]; other site 291112008125 domain II; other site 291112008126 domain III; other site 291112008127 nucleotide binding site [chemical binding]; other site 291112008128 catalytic site [active] 291112008129 domain IV; other site 291112008130 HMMPfam hit to PF01751, Toprim domain, score 1.1e-38 291112008131 HMMSmart hit to SM00493, no description, score 5.8e-32 291112008132 HMMSmart hit to SM00436, no description, score 1.1e-34 291112008133 HMMPfam hit to PF01131, DNA topoisomerase, score 1.7e-174 291112008134 HMMSmart hit to SM00437, no description, score 2.2e-102 291112008135 Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086 291112008136 putative catalytic site [active] 291112008137 putative phosphate binding site [ion binding]; other site 291112008138 active site 291112008139 metal binding site A [ion binding]; metal-binding site 291112008140 DNA binding site [nucleotide binding] 291112008141 putative AP binding site [nucleotide binding]; other site 291112008142 putative metal binding site B [ion binding]; other site 291112008143 HMMPfam hit to PF03372, Endonuclease/Exonuclease/phosphatase fa, score 2.6e-49 291112008144 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112008145 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112008146 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 5e-15 291112008147 Phage Tail Collar Domain; Region: Collar; pfam07484 291112008148 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 5e-20 291112008149 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112008150 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 4.4e-35 291112008151 PGAP1-like protein; Region: PGAP1; pfam07819 291112008152 1 probable transmembrane helix predicted for PAT3491 by TMHMM2.0 at aa 20-37 291112008153 2 probable transmembrane helices predicted for PAT3490 by TMHMM2.0 at aa 21-43 and 47-69 291112008154 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355 291112008155 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 291112008156 DNA binding site [nucleotide binding] 291112008157 1 probable transmembrane helix predicted for PAT3489 by TMHMM2.0 at aa 136-158 291112008158 HMMPfam hit to PF00486, Transcriptional regulatory protein, C ter, score 4e-06 291112008159 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841 291112008160 Phage tail sheath protein; Region: Phage_sheath_1; cl01389 291112008161 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112008162 Phage tail sheath protein; Region: Phage_sheath_1; cl01389 291112008163 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112008164 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112008165 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841 291112008166 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 291112008167 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112008168 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112008169 Gene 25-like lysozyme; Region: GPW_gp25; pfam04965 291112008170 HMMPfam hit to PF04965, GPW / gp25 family, score 2.7e-34 291112008171 conserved hypothetical protein, phage tail-like region; Region: TIGR02243 291112008172 Phage Tail Collar Domain; Region: Collar; pfam07484 291112008173 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 1.4e-12 291112008174 ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464 291112008175 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112008176 Walker A motif; other site 291112008177 ATP binding site [chemical binding]; other site 291112008178 Walker B motif; other site 291112008179 HMMSmart hit to SM00382, no description, score 1.7e-14 291112008180 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 4.9e-38 291112008181 Protein of unknown function (DUF4255); Region: DUF4255; pfam14065 291112008182 2 probable transmembrane helices predicted for PAT3470 by TMHMM2.0 at aa 212-234 and 238-257 291112008183 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112008184 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 4.8e-18 291112008185 3 probable transmembrane helices predicted for PAT3469 by TMHMM2.0 at aa 19-41, 56-78 and 99-121 291112008186 GntP family permease; Region: GntP_permease; pfam02447 291112008187 fructuronate transporter; Provisional; Region: PRK10034; cl15264 291112008188 HMMPfam hit to PF02447, GntP family permease, score 6.3e-173 291112008189 12 probable transmembrane helices predicted for PAT3468 by TMHMM2.0 at aa 4-22, 29-51, 104-126, 139-158, 173-195, 235-257, 281-300, 313-335, 345-367, 374-396, 401-423 and 436-458 291112008190 HMMPfam hit to PF06808, DctM-like transporters, score 0.0022 291112008191 HMMPfam hit to PF03600, Citrate transporter, score 7.2e-06 291112008192 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 291112008193 Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238 291112008194 putative NAD(P) binding site [chemical binding]; other site 291112008195 active site 291112008196 putative substrate binding site [chemical binding]; other site 291112008197 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.00022 291112008198 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 5.1e-12 291112008199 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 6.2e-07 291112008200 HMMPfam hit to PF07993, Male sterility protein, score 7.7e-08 291112008201 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 291112008202 helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420 291112008203 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 291112008204 HMMPfam hit to PF00455, Bacterial regulatory proteins, deoR family, score 9.7e-45 291112008205 HMMPfam hit to PF08220, DeoR-like helix-turn-helix domain, score 2.1e-10 291112008206 HMMSmart hit to SM00420, no description, score 6.1e-17 291112008207 HMMPfam hit to PF08279, HTH domain, score 2.3e-06 291112008208 Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622 291112008209 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 2.2e-49 291112008210 putative aldolase; Validated; Region: PRK08130 291112008211 intersubunit interface [polypeptide binding]; other site 291112008212 active site 291112008213 Zn2+ binding site [ion binding]; other site 291112008214 HMMPfam hit to PF00596, Class II Aldolase and Adducin N-terminal, score 7.8e-58 291112008215 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395 291112008216 HMMPfam hit to PF07005, Protein of unknown function, DUF1537, score 2.9e-70 291112008217 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 291112008218 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 291112008219 HMMPfam hit to PF03446, NAD binding domain of 6-phosphoglucona, score 8.6e-58 291112008220 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.0034 291112008221 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD b, score 0.00015 291112008222 formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027 291112008223 N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875 291112008224 Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648 291112008225 putative active site [active] 291112008226 putative substrate binding site [chemical binding]; other site 291112008227 putative cosubstrate binding site; other site 291112008228 catalytic site [active] 291112008229 HMMPfam hit to PF00551, Formyl transferase, score 6.7e-74 291112008230 HMMPfam hit to PF01842, ACT domain, score 0.00064 291112008231 SEC-C motif; Region: SEC-C; pfam02810 291112008232 hypothetical protein; Provisional; Region: PRK04233 291112008233 HMMPfam hit to PF02810, SEC-C motif, score 0.0002 291112008234 HMMPfam hit to PF02810, SEC-C motif, score 0.00048 291112008235 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112008236 active site 291112008237 response regulator of RpoS; Provisional; Region: PRK10693 291112008238 phosphorylation site [posttranslational modification] 291112008239 intermolecular recognition site; other site 291112008240 dimerization interface [polypeptide binding]; other site 291112008241 HMMPfam hit to PF00072, Response regulator receiver domain, score 4.1e-30 291112008242 HMMSmart hit to SM00448, no description, score 3.4e-26 291112008243 Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541 291112008244 active site 291112008245 tetramer interface; other site 291112008246 HMMPfam hit to PF00483, Nucleotidyl transferase, score 4.9e-11 291112008247 Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004 291112008248 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 291112008249 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 291112008250 UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984 291112008251 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 6e-86 291112008252 HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 7.1e-50 291112008253 HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 7e-33 291112008254 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 291112008255 UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253 291112008256 putative NAD(P) binding site [chemical binding]; other site 291112008257 active site 291112008258 putative substrate binding site [chemical binding]; other site 291112008259 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.00073 291112008260 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 1.3e-57 291112008261 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 1.7e-09 291112008262 HMMPfam hit to PF07993, Male sterility protein, score 0.00039 291112008263 global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947 291112008264 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 291112008265 HMMSmart hit to SM00528, no description, score 4.6e-22 291112008266 HMMPfam hit to PF00816, H-NS histone family, score 3.6e-44 291112008267 thymidine kinase; Provisional; Region: PRK04296 291112008268 HMMPfam hit to PF00265, Thymidine kinase, score 1.1e-87 291112008269 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805 291112008270 Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122 291112008271 putative catalytic cysteine [active] 291112008272 C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178 291112008273 putative active site [active] 291112008274 metal binding site [ion binding]; metal-binding site 291112008275 HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 8.8e-229 291112008276 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 2.2e-08 291112008277 hypothetical protein; Provisional; Region: PRK11111 291112008278 HMMPfam hit to PF01914, MarC family integral membrane protein, score 2.1e-89 291112008279 6 probable transmembrane helices predicted for PAT3450 by TMHMM2.0 at aa 15-34, 47-69, 79-97, 118-140, 150-168 and 189-211 291112008280 oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104 291112008281 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 291112008282 peptide binding site [polypeptide binding]; other site 291112008283 1 probable transmembrane helix predicted for PAT3449 by TMHMM2.0 at aa 7-29 291112008284 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 4.1e-81 291112008285 oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104 291112008286 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 291112008287 peptide binding site [polypeptide binding]; other site 291112008288 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 2.8e-82 291112008289 oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471 291112008290 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112008291 dimer interface [polypeptide binding]; other site 291112008292 conserved gate region; other site 291112008293 putative PBP binding loops; other site 291112008294 ABC-ATPase subunit interface; other site 291112008295 6 probable transmembrane helices predicted for PAT3447 by TMHMM2.0 at aa 13-30, 100-122, 134-156, 166-188, 228-250 and 278-300 291112008296 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.2e-54 291112008297 oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406 291112008298 N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911 291112008299 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112008300 dimer interface [polypeptide binding]; other site 291112008301 conserved gate region; other site 291112008302 ABC-ATPase subunit interface; other site 291112008303 6 probable transmembrane helices predicted for PAT3446 by TMHMM2.0 at aa 40-62, 103-125, 138-160, 164-183, 214-236 and 268-290 291112008304 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 4.2e-42 291112008305 oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473 291112008306 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 291112008307 Walker A/P-loop; other site 291112008308 ATP binding site [chemical binding]; other site 291112008309 Q-loop/lid; other site 291112008310 ABC transporter signature motif; other site 291112008311 Walker B; other site 291112008312 D-loop; other site 291112008313 H-loop/switch region; other site 291112008314 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 291112008315 HMMSmart hit to SM00382, no description, score 1.2e-14 291112008316 HMMPfam hit to PF00005, ABC transporter, score 1.4e-58 291112008317 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 7.4e-27 291112008318 oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079 291112008319 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 291112008320 Walker A/P-loop; other site 291112008321 ATP binding site [chemical binding]; other site 291112008322 Q-loop/lid; other site 291112008323 ABC transporter signature motif; other site 291112008324 Walker B; other site 291112008325 D-loop; other site 291112008326 H-loop/switch region; other site 291112008327 oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727 291112008328 HMMSmart hit to SM00382, no description, score 3.9e-18 291112008329 HMMPfam hit to PF00005, ABC transporter, score 3.7e-63 291112008330 HMMPfam hit to PF08352, Oligopeptide/dipeptide transporter, C-termi, score 8.2e-36 291112008331 dsDNA-mimic protein; Reviewed; Region: PRK05094 291112008332 HMMPfam hit to PF04269, Protein of unknown function, DUF440, score 1.4e-36 291112008333 cardiolipin synthetase; Reviewed; Region: cls; PRK01642 291112008334 Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396 291112008335 Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152 291112008336 putative active site [active] 291112008337 catalytic site [active] 291112008338 Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158 291112008339 putative active site [active] 291112008340 catalytic site [active] 291112008341 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 8.4e-07; HMMSmart hit to SM00155, no description, score 6.1e-05 291112008342 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 3.4e-07; HMMSmart hit to SM00155, no description, score 0.00039 291112008343 2 probable transmembrane helices predicted for PAT3442 by TMHMM2.0 at aa 10-32 and 39-61 291112008344 transport protein TonB; Provisional; Region: PRK10819 291112008345 Gram-negative bacterial tonB protein; Region: TonB; pfam03544 291112008346 1 probable transmembrane helix predicted for PAT3440 by TMHMM2.0 at aa 13-35 291112008347 HMMPfam hit to PF03544, Gram-negative bacterial tonB protein, score 3.7e-11 291112008348 Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442 291112008349 HMMPfam hit to PF03061, Thioesterase superfamily, score 6.3e-21 291112008350 intracellular septation protein A; Reviewed; Region: PRK00259 291112008351 HMMPfam hit to PF04279, Intracellular septation protein A, score 1.9e-102 291112008352 5 probable transmembrane helices predicted for PAT3438 by TMHMM2.0 at aa 22-44, 51-68, 78-95, 119-141 and 151-173 291112008353 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 291112008354 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 291112008355 Sulfate transporter family; Region: Sulfate_transp; pfam00916 291112008356 Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042 291112008357 11 probable transmembrane helices predicted for PAT3437 by TMHMM2.0 at aa 28-45, 49-71, 76-98, 102-124, 145-167, 182-199, 206-225, 257-279, 331-353, 358-377 and 390-412 291112008358 HMMPfam hit to PF00860, Permease family, score 0.013 291112008359 HMMPfam hit to PF00916, Sulfate transporter family, score 1.6e-66 291112008360 HMMPfam hit to PF01740, STAS domain, score 1.2e-05 291112008361 Predicted transcriptional regulator [Transcription]; Region: COG4190 291112008362 MarR family; Region: MarR_2; cl17246 291112008363 Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254 291112008364 HMMPfam hit to PF06316, Enterobacterial Ail/Lom protein, score 1.7e-18 291112008365 1 probable transmembrane helix predicted for PAT3434 by TMHMM2.0 at aa 5-24 291112008366 hypothetical protein; Provisional; Region: PRK02868 291112008367 HMMPfam hit to PF06790, Uncharacterised protein family (UPF0259), score 2.4e-94 291112008368 6 probable transmembrane helices predicted for PAT3433 by TMHMM2.0 at aa 20-42, 89-111, 132-149, 154-176, 189-211 and 221-243 291112008369 outer membrane protein W; Provisional; Region: PRK10959 291112008370 HMMPfam hit to PF03922, OmpW family, score 4.9e-85 291112008371 tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200 291112008372 Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724 291112008373 substrate binding site [chemical binding]; other site 291112008374 active site 291112008375 catalytic residues [active] 291112008376 heterodimer interface [polypeptide binding]; other site 291112008377 HMMPfam hit to PF00290, Tryptophan synthase alpha chain, score 5.1e-136 291112008378 tryptophan synthase, beta subunit; Region: trpB; TIGR00263 291112008379 Tryptophan synthase-beta: Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446 291112008380 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112008381 catalytic residue [active] 291112008382 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 4.8e-118 291112008383 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427 291112008384 Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331 291112008385 active site 291112008386 ribulose/triose binding site [chemical binding]; other site 291112008387 phosphate binding site [ion binding]; other site 291112008388 substrate (anthranilate) binding pocket [chemical binding]; other site 291112008389 product (indole) binding pocket [chemical binding]; other site 291112008390 Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405 291112008391 active site 291112008392 HMMPfam hit to PF00697, N-(5'phosphoribosyl)anthranilate (PRA) isome, score 2.8e-72 291112008393 HMMPfam hit to PF00218, Indole-3-glycerol phosphate synthase, score 1.4e-139 291112008394 anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188 291112008395 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 291112008396 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 291112008397 HMMPfam hit to PF00591, Glycosyl transferase family, a/b doma, score 2.1e-141 291112008398 HMMPfam hit to PF02885, Glycosyl transferase family, helical, score 2.8e-19 291112008399 Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743 291112008400 Glutamine amidotransferase class-I; Region: GATase; pfam00117 291112008401 glutamine binding [chemical binding]; other site 291112008402 catalytic triad [active] 291112008403 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 8.8e-68 291112008404 anthranilate synthase component I; Provisional; Region: PRK13564 291112008405 Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715 291112008406 chorismate binding enzyme; Region: Chorismate_bind; pfam00425 291112008407 HMMPfam hit to PF00425, chorismate binding enzyme, score 1.4e-156 291112008408 HMMPfam hit to PF04715, Anthranilate synthase component I, N, score 7.5e-22 291112008409 Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325 291112008410 The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548 291112008411 active site 291112008412 HMMPfam hit to PF00704, Glycosyl hydrolases family, score 8.1e-56; HMMSmart hit to SM00636, no description, score 3.1e-45 291112008413 Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538 291112008414 Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538 291112008415 Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325 291112008416 The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548 291112008417 active site 291112008418 HMMPfam hit to PF00704, Glycosyl hydrolases family, score 8.8e-64; HMMSmart hit to SM00636, no description, score 1.5e-58 291112008419 putative transposase OrfB; Reviewed; Region: PHA02517 291112008420 HTH-like domain; Region: HTH_21; pfam13276 291112008421 Integrase core domain; Region: rve; pfam00665 291112008422 Integrase core domain; Region: rve_2; pfam13333 291112008423 HMMPfam hit to PF00665, Integrase core domain, score 2.2e-42 291112008424 Homeodomain-like domain; Region: HTH_23; cl17451 291112008425 Helix-turn-helix domain; Region: HTH_28; pfam13518 291112008426 Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613 291112008427 Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102 291112008428 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438 291112008429 HMMPfam hit to PF02811, PHP domain, score 2.2e-05 291112008430 hypothetical protein; Provisional; Region: PRK11630 291112008431 HMMPfam hit to PF01300, yrdC domain, score 1.1e-73 291112008432 23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700 291112008433 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 291112008434 RNA binding surface [nucleotide binding]; other site 291112008435 Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556 291112008436 probable active site [active] 291112008437 HMMSmart hit to SM00363, no description, score 4.2e-08 291112008438 HMMPfam hit to PF01479, S4 domain, score 3e-07 291112008439 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 2.5e-14 291112008440 ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109 291112008441 Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557 291112008442 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561 291112008443 homodimer interface [polypeptide binding]; other site 291112008444 Walker A motif; other site 291112008445 ATP binding site [chemical binding]; other site 291112008446 hydroxycobalamin binding site [chemical binding]; other site 291112008447 Walker B motif; other site 291112008448 HMMPfam hit to PF02572, ATP:corrinoid adenosyltransferase BtuR, score 7.5e-114 291112008449 putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945 291112008450 Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340 291112008451 NADP binding site [chemical binding]; other site 291112008452 homodimer interface [polypeptide binding]; other site 291112008453 active site 291112008454 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.7e-30 291112008455 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112008456 PA-IL-like protein; Region: PA-IL; pfam07828 291112008457 HMMPfam hit to PF07828, PA-IL-like protein, score 3.6e-50 291112008458 Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496 291112008459 putative inner membrane peptidase; Provisional; Region: PRK11778 291112008460 Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023 291112008461 tandem repeat interface [polypeptide binding]; other site 291112008462 oligomer interface [polypeptide binding]; other site 291112008463 active site residues [active] 291112008464 HMMPfam hit to PF08496, Peptidase family S49 N-terminal, score 3e-95 291112008465 1 probable transmembrane helix predicted for PAT3410 by TMHMM2.0 at aa 7-29 291112008466 HMMPfam hit to PF01343, Peptidase family S49, score 3.6e-52 291112008467 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 291112008468 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.5e-10 291112008469 DNA topoisomerase I subunit omega; Validated; Region: PRK07561 291112008470 TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I. Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363 291112008471 active site 291112008472 interdomain interaction site; other site 291112008473 putative metal-binding site [ion binding]; other site 291112008474 nucleotide binding site [chemical binding]; other site 291112008475 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186 291112008476 domain I; other site 291112008477 DNA binding groove [nucleotide binding] 291112008478 phosphate binding site [ion binding]; other site 291112008479 domain II; other site 291112008480 domain III; other site 291112008481 nucleotide binding site [chemical binding]; other site 291112008482 catalytic site [active] 291112008483 domain IV; other site 291112008484 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 291112008485 Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272 291112008486 Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272 291112008487 HMMPfam hit to PF01751, Toprim domain, score 4.6e-35 291112008488 HMMSmart hit to SM00493, no description, score 8.9e-31 291112008489 HMMSmart hit to SM00436, no description, score 3.2e-46 291112008490 HMMPfam hit to PF01131, DNA topoisomerase, score 3.4e-186 291112008491 HMMSmart hit to SM00437, no description, score 2e-122 291112008492 HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 0.03 291112008493 HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 7.4e-13 291112008494 HMMPfam hit to PF08272, Topoisomerase I zinc-ribbon-like, score 1.1e-15 291112008495 HMMPfam hit to PF08272, Topoisomerase I zinc-ribbon-like, score 4.4e-20 291112008496 transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681 291112008497 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112008498 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 291112008499 dimerization interface [polypeptide binding]; other site 291112008500 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.7e-14 291112008501 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.9e-42 291112008502 aconitate hydratase; Validated; Region: PRK09277 291112008503 Aconitase A catalytic domain; Region: AcnA_IRP; cd01586 291112008504 substrate binding site [chemical binding]; other site 291112008505 ligand binding site [chemical binding]; other site 291112008506 Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580 291112008507 substrate binding site [chemical binding]; other site 291112008508 HMMPfam hit to PF00330, Aconitase family (aconitate hydratase), score 8.2e-252 291112008509 HMMPfam hit to PF00694, Aconitase C-terminal domain, score 1.7e-62 291112008510 GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641 291112008511 dimerization interface [polypeptide binding]; other site 291112008512 active site 291112008513 HMMPfam hit to PF00925, GTP cyclohydrolase II, score 2e-115 291112008514 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 291112008515 Predicted membrane protein [Function unknown]; Region: COG3771 291112008516 HMMPfam hit to PF06305, Protein of unknown function (DUF1049), score 9.3e-51 291112008517 2 probable transmembrane helices predicted for PAT3401 by TMHMM2.0 at aa 5-23 and 43-65 291112008518 tetratricopeptide repeat protein; Provisional; Region: PRK11788 291112008519 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 291112008520 binding surface 291112008521 TPR motif; other site 291112008522 HMMSmart hit to SM00028, no description, score 58 291112008523 HMMPfam hit to PF00515, no description, score 0.11; HMMSmart hit to SM00028, no description, score 1.1 291112008524 HMMPfam hit to PF00515, no description, score 0.18; HMMSmart hit to SM00028, no description, score 13 291112008525 Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725 291112008526 active site 291112008527 dimer interface [polypeptide binding]; other site 291112008528 HMMPfam hit to PF00215, Orotidine 5'-phosphate decarboxylase / HUMP, score 4.9e-88 291112008529 translation initiation factor Sui1; Validated; Region: PRK06824 291112008530 Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567 291112008531 putative rRNA binding site [nucleotide binding]; other site 291112008532 HMMPfam hit to PF01253, Translation initiation factor SUI1, score 2.6e-33 291112008533 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 291112008534 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112008535 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.1e-11 291112008536 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558 291112008537 HMMPfam hit to PF07080, Protein of unknown function (DUF1348), score 2.8e-94 291112008538 HipA N-terminal domain; Region: Couple_hipA; pfam13657 291112008539 Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550 291112008540 HipA-like N-terminal domain; Region: HipA_N; pfam07805 291112008541 HipA-like C-terminal domain; Region: HipA_C; pfam07804 291112008542 HMMPfam hit to PF07804, HipA-like C-terminal domain, score 7.5e-31 291112008543 HMMPfam hit to PF07805, HipA-like N-terminal domain, score 3.1e-11 291112008544 HMMSmart hit to SM00530, no description, score 0.00012 291112008545 Fic family protein [Function unknown]; Region: COG3177 291112008546 Fic/DOC family; Region: Fic; pfam02661 291112008547 HMMPfam hit to PF02661, Fic protein family, score 5.5e-18 291112008548 Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564 291112008549 Predicted amidohydrolase [General function prediction only]; Region: COG0388 291112008550 putative active site [active] 291112008551 catalytic triad [active] 291112008552 putative dimer interface [polypeptide binding]; other site 291112008553 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 6e-70 291112008554 DDE superfamily endonuclease; Region: DDE_3; pfam13358 291112008555 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335 291112008556 3 probable transmembrane helices predicted for PAT3388 by TMHMM2.0 at aa 85-103, 135-157 and 177-196 291112008557 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 291112008558 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 291112008559 Peptidase M35 family; Region: M35_like; cl03449 291112008560 active site 291112008561 Zn binding site [ion binding]; other site 291112008562 Yersinia/Haemophilus virulence surface antigen; Region: Peptidase_C58; pfam03543 291112008563 HMMPfam hit to PF03543, Yersinia/Haemophilus virulence surface, score 2.1e-100 291112008564 C-terminal region of Pasteurella multocida toxin residues 569-1285; Region: PMT_C; pfam11647 291112008565 Protein of unknown function (DUF4255); Region: DUF4255; pfam14065 291112008566 ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464 291112008567 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112008568 Walker A motif; other site 291112008569 ATP binding site [chemical binding]; other site 291112008570 Walker B motif; other site 291112008571 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.7e-33 291112008572 HMMSmart hit to SM00382, no description, score 2.6e-13 291112008573 conserved hypothetical protein, phage tail-like region; Region: TIGR02243 291112008574 Gene 25-like lysozyme; Region: GPW_gp25; pfam04965 291112008575 HMMPfam hit to PF04965, GPW / gp25 family, score 1.4e-36 291112008576 Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796 291112008577 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 291112008578 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112008579 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841 291112008580 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112008581 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112008582 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; cl17313 291112008583 exoribonuclease II; Provisional; Region: PRK05054 291112008584 Ribonuclease B OB domain; Region: OB_RNB; pfam08206 291112008585 RNB domain; Region: RNB; pfam00773 291112008586 S1 RNA binding domain; Region: S1; pfam00575 291112008587 HMMPfam hit to PF00575, S1 RNA binding domain, score 0.0017 291112008588 HMMPfam hit to PF00773, RNB-like protein, score 1.5e-88 291112008589 HMMPfam hit to PF08206, Ribonuclease B OB domain, score 5.1e-22 291112008590 HMMSmart hit to SM00357, no description, score 4.8e-12 291112008591 endonuclease III; Provisional; Region: PRK10702 291112008592 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 291112008593 minor groove reading motif; other site 291112008594 helix-hairpin-helix signature motif; other site 291112008595 substrate binding pocket [chemical binding]; other site 291112008596 active site 291112008597 iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525 291112008598 HMMSmart hit to SM00525, no description, score 4.4e-05 291112008599 HMMSmart hit to SM00478, no description, score 1.1e-53 291112008600 HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair, score 2.3e-20 291112008601 HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 5.3e-05 291112008602 electron transport complex RsxE subunit; Provisional; Region: PRK12405 291112008603 5 probable transmembrane helices predicted for PAT3366 by TMHMM2.0 at aa 34-56, 69-86, 90-112, 124-146 and 184-206 291112008604 HMMPfam hit to PF02508, Rnf-Nqr subunit, membrane protein, score 2.1e-110 291112008605 electron transport complex protein RnfG; Validated; Region: PRK01908 291112008606 HMMPfam hit to PF04205, FMN-binding domain, score 2.5e-27 291112008607 1 probable transmembrane helix predicted for PAT3365 by TMHMM2.0 at aa 10-29 291112008608 electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816 291112008609 HMMPfam hit to PF03116, NQR2, RnfD, RnfE family, score 1.4e-146 291112008610 8 probable transmembrane helices predicted for PAT3364 by TMHMM2.0 at aa 30-49, 53-75, 88-119, 134-153, 249-271, 281-303, 310-327 and 332-351 291112008611 Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656 291112008612 SLBB domain; Region: SLBB; pfam10531 291112008613 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655 291112008614 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00018 291112008615 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00024 291112008616 HMMPfam hit to PF01512, Respiratory-chain NADH dehydrogenase, score 1.4e-76 291112008617 ferredoxin; Provisional; Region: PRK08764 291112008618 Putative Fe-S cluster; Region: FeS; pfam04060 291112008619 4Fe-4S binding domain; Region: Fer4; pfam00037 291112008620 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 3.5e-05 291112008621 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 1.2e-07 291112008622 HMMPfam hit to PF04060, Putative Fe-S cluster, score 5.8e-16 291112008623 1 probable transmembrane helix predicted for PAT3362 by TMHMM2.0 at aa 4-26 291112008624 electron transport complex protein RsxA; Provisional; Region: PRK05151 291112008625 HMMPfam hit to PF02508, Rnf-Nqr subunit, membrane protein, score 3.8e-108 291112008626 6 probable transmembrane helices predicted for PAT3361 by TMHMM2.0 at aa 4-26, 38-60, 70-92, 99-121, 131-153 and 165-187 291112008627 Protein of unknown function (DUF2569); Region: DUF2569; pfam10754 291112008628 4 probable transmembrane helices predicted for PAT3360 by TMHMM2.0 at aa 13-38, 53-75, 88-110 and 115-132 291112008629 putative oxidoreductase; Provisional; Region: PRK11579 291112008630 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 291112008631 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 291112008632 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 8.2e-39 291112008633 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindin, score 4.1e-05 291112008634 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 4.8e-18 291112008635 Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385 291112008636 SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593 291112008637 9 probable transmembrane helices predicted for PAT3358 by TMHMM2.0 at aa 19-36, 41-63, 76-98, 108-130, 137-159, 174-196, 216-233, 238-260 and 291-313 291112008638 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 291112008639 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 291112008640 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 7e-16 291112008641 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 0.025 291112008642 Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192 291112008643 Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884 291112008644 Carbamoyltransferase; Region: CmcH_NodU; pfam02543 291112008645 HMMPfam hit to PF02543, Carbamoyltransferase, score 1.6e-99 291112008646 DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041 291112008647 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 291112008648 inhibitor-cofactor binding pocket; inhibition site 291112008649 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112008650 catalytic residue [active] 291112008651 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 6.1e-71 291112008652 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.00074 291112008653 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 291112008654 active site 291112008655 HMMPfam hit to PF00535, Glycosyl transferase family, score 5.7e-08 291112008656 Glycosyltransferase like family 2; Region: Glyco_tranf_2_2; pfam10111 291112008657 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 291112008658 active site 291112008659 HMMPfam hit to PF00535, Glycosyl transferase family, score 2.9e-25 291112008660 Myo-inositol-1-phosphate synthase [Lipid metabolism]; Region: INO1; COG1260 291112008661 Myo-inositol-1-phosphate synthase; Region: NAD_binding_5; cl00554 291112008662 HMMPfam hit to PF07994, Myo-inositol-1-phosphate synthase, score 3.6e-40 291112008663 HMMPfam hit to PF01658, Myo-inositol-1-phosphate synthase, score 4e-29 291112008664 Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192 291112008665 Carbamoyltransferase; Region: CmcH_NodU; pfam02543 291112008666 HMMPfam hit to PF02543, Carbamoyltransferase, score 4.7e-61 291112008667 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483 291112008668 FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289 291112008669 active site 291112008670 HMMPfam hit to PF00459, Inositol monophosphatase family, score 3.1e-40 291112008671 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 291112008672 Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535 291112008673 N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; pfam02709 291112008674 HMMPfam hit to PF00535, Glycosyl transferase family, score 2.7e-14 291112008675 Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534 291112008676 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 291112008677 11 probable transmembrane helices predicted for PAT3348 by TMHMM2.0 at aa 13-35, 50-72, 85-107, 132-150, 157-179, 189-211, 238-260, 275-297, 318-340, 355-377 and 386-408 291112008678 HMMPfam hit to PF01554, MatE, score 6.6e-23 291112008679 Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118 291112008680 HMMPfam hit to PF02604, Phd_YefM, score 2.8e-05 291112008681 nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of...; Region: nylC_like; cd02252 291112008682 putative active site pocket [active] 291112008683 cleavage site 291112008684 HMMPfam hit to PF03576, Peptidase family T4, score 2e-38 291112008685 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 291112008686 HMMPfam hit to PF04324, BFD-like [2Fe-2S] binding domain, score 2.2e-07 291112008687 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 3.4e-22 291112008688 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510 291112008689 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 291112008690 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 8.7e-84 291112008691 hydroxyproline-2-epimerase; Provisional; Region: PRK13970 291112008692 hydroxyproline-2-epimerase; Provisional; Region: PRK13971 291112008693 HMMPfam hit to PF05544, Proline racemase, score 1.3e-129 291112008694 PAS fold; Region: PAS_4; pfam08448 291112008695 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 291112008696 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112008697 HMMPfam hit to PF08448, PAS fold, score 4.6e-11 291112008698 HMMSmart hit to SM00342, no description, score 1.1e-23 291112008699 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.1e-10 291112008700 Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329 291112008701 Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408 291112008702 inhibitor site; inhibition site 291112008703 active site 291112008704 dimer interface [polypeptide binding]; other site 291112008705 catalytic residue [active] 291112008706 HMMPfam hit to PF00701, Dihydrodipicolinate synthetase family, score 1.5e-52 291112008707 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012 291112008708 Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129 291112008709 dimer interface [polypeptide binding]; other site 291112008710 NADP binding site [chemical binding]; other site 291112008711 catalytic residues [active] 291112008712 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.2e-14 291112008713 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 291112008714 HMMPfam hit to PF00324, Amino acid permease, score 8.1e-07 291112008715 14 probable transmembrane helices predicted for PAT3327 by TMHMM2.0 at aa 30-52, 57-79, 100-122, 142-164, 171-193, 213-235, 248-270, 293-315, 349-371, 376-398, 410-432, 437-454, 471-493 and 497-519 291112008716 Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816 291112008717 adenosine deaminase; Provisional; Region: PRK09358 291112008718 active site 291112008719 HMMPfam hit to PF00962, Adenosine/AMP deaminase, score 3.6e-106 291112008720 Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097 291112008721 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339 291112008722 HMMPfam hit to PF06097, Bacterial protein of unknown function (DUF94, score 1.1e-139 291112008723 1 probable transmembrane helix predicted for PAT3325 by TMHMM2.0 at aa 5-24 291112008724 mannose-6-phosphate isomerase; Provisional; Region: PRK15131 291112008725 Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429 291112008726 Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429 291112008727 HMMPfam hit to PF01238, Phosphomannose isomerase type I, score 6.4e-129 291112008728 fumarate hydratase; Reviewed; Region: fumC; PRK00485 291112008729 Class II fumarases; Region: Fumarase_classII; cd01362 291112008730 active site 291112008731 tetramer interface [polypeptide binding]; other site 291112008732 HMMPfam hit to PF00206, Lyase, score 1.5e-186 291112008733 Plasmid maintenance system killer protein; Region: Plasmid_killer; pfam05015 291112008734 HMMPfam hit to PF05015, Plasmid maintenance system killer prot, score 1.2e-50 291112008735 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112008736 non-specific DNA binding site [nucleotide binding]; other site 291112008737 salt bridge; other site 291112008738 sequence-specific DNA binding site [nucleotide binding]; other site 291112008739 HMMSmart hit to SM00530, no description, score 2.5e-06 291112008740 HMMPfam hit to PF01381, Helix-turn-helix, score 2.4e-08 291112008741 RES domain; Region: RES; cl02411 291112008742 putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293 291112008743 Protein of unknown function (DUF2384); Region: DUF2384; cl17718 291112008744 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_11; cd07261 291112008745 putative dimer interface [polypeptide binding]; other site 291112008746 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 291112008747 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 4.6e-09 291112008748 DNA replication terminus site-binding protein; Provisional; Region: PRK02951 291112008749 HMMPfam hit to PF05472, DNA replication terminus site-binding protei, score 7.1e-145 291112008750 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112008751 Radical SAM superfamily; Region: Radical_SAM; pfam04055 291112008752 FeS/SAM binding site; other site 291112008753 HMMPfam hit to PF04055, Radical SAM superfamily, score 6.8e-08 291112008754 LysE type translocator; Region: LysE; cl00565 291112008755 6 probable transmembrane helices predicted for PAT3312 by TMHMM2.0 at aa 4-26, 35-57, 67-84, 115-137, 147-169 and 182-204 291112008756 HMMPfam hit to PF01810, LysE type translocator, score 4.6e-28 291112008757 Chitin binding domain; Region: Chitin_bind_3; pfam03067 291112008758 HMMPfam hit to PF03067, Chitin binding domain, score 2.7e-36 291112008759 Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551 291112008760 PspA/IM30 family; Region: PspA_IM30; pfam04012 291112008761 HMMPfam hit to PF04012, PspA/IM30 family, score 2.3e-44 291112008762 Protein of unknown function (DUF2491); Region: DUF2491; pfam10679 291112008763 Predicted membrane protein [Function unknown]; Region: COG3766 291112008764 Domain of Unknown Function (DUF350); Region: DUF350; pfam03994 291112008765 Domain of Unknown Function (DUF350); Region: DUF350; pfam03994 291112008766 HMMPfam hit to PF03994, Domain of Unknown Function (DUF350), score 3.3e-14 291112008767 4 probable transmembrane helices predicted for PAT3307 by TMHMM2.0 at aa 21-43, 58-80, 87-109 and 124-143 291112008768 HMMPfam hit to PF03994, Domain of Unknown Function (DUF350), score 1.8e-15 291112008769 Protein of unknown function (DUF1190); Region: DUF1190; cl10031 291112008770 1 probable transmembrane helix predicted for PAT3306 by TMHMM2.0 at aa 23-42 291112008771 Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754 291112008772 HMMPfam hit to PF03738, Glutathionylspermidine synthase, score 2.1e-207 291112008773 Protein of unknown function (DUF1778); Region: DUF1778; pfam08681 291112008774 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.00088 291112008775 1 probable transmembrane helix predicted for PAT3302 by TMHMM2.0 at aa 189-211 291112008776 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 291112008777 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112008778 putative substrate translocation pore; other site 291112008779 12 probable transmembrane helices predicted for PAT3301 by TMHMM2.0 at aa 34-56, 71-93, 106-125, 129-151, 158-177, 187-209, 241-263, 273-295, 302-324, 330-352, 365-387 and 391-413 291112008780 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3e-42 291112008781 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112008782 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112008783 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 291112008784 dimerization interface [polypeptide binding]; other site 291112008785 substrate binding pocket [chemical binding]; other site 291112008786 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.3e-21 291112008787 HMMPfam hit to PF03466, LysR substrate binding domain, score 4.5e-45 291112008788 MarR family; Region: MarR_2; cl17246 291112008789 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 291112008790 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 291112008791 HMMPfam hit to PF00480, ROK family, score 6.8e-24 291112008792 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 291112008793 AAA domain; Region: AAA_26; pfam13500 291112008794 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 6.2e-16 291112008795 Protein of unknown function (DUF1161); Region: DUF1161; pfam06649 291112008796 HMMPfam hit to PF06649, Protein of unknown function (DUF1161), score 2.8e-27 291112008797 hypothetical protein; Provisional; Region: PRK13659 291112008798 HMMPfam hit to PF06932, Protein of unknown function (DUF1283), score 4e-58 291112008799 malonic semialdehyde reductase; Provisional; Region: PRK10538 291112008800 classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346 291112008801 putative NAD(P) binding site [chemical binding]; other site 291112008802 homodimer interface [polypeptide binding]; other site 291112008803 homotetramer interface [polypeptide binding]; other site 291112008804 active site 291112008805 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 2.9e-05 291112008806 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.2e-30 291112008807 Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332 291112008808 active sites [active] 291112008809 tetramer interface [polypeptide binding]; other site 291112008810 HMMPfam hit to PF00221, Phenylalanine and histidine ammonia-lyase, score 8.5e-114 291112008811 Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325 291112008812 The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548 291112008813 active site 291112008814 Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215 291112008815 aromatic chitin/cellulose binding site residues [chemical binding]; other site 291112008816 HMMPfam hit to PF00704, Glycosyl hydrolases family, score 2.9e-60; HMMSmart hit to SM00636, no description, score 6e-49 291112008817 HMMSmart hit to SM00495, no description, score 3.9e-06 291112008818 HMMPfam hit to PF02839, Carbohydrate binding domain, score 1.4e-07 291112008819 2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984 291112008820 hypothetical protein; Provisional; Region: PRK07236 291112008821 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 291112008822 HMMPfam hit to PF01494, FAD binding domain, score 0.00014 291112008823 Cupin domain; Region: Cupin_2; cl17218 291112008824 YcfA-like protein; Region: YcfA; pfam07927 291112008825 HMMPfam hit to PF07927, YcfA-like protein, score 3.8e-18 291112008826 Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681 291112008827 HMMPfam hit to PF03681, Uncharacterised protein family (UPF0150), score 2.7e-15 291112008828 arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291 291112008829 ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035 291112008830 P loop; other site 291112008831 Nucleotide binding site [chemical binding]; other site 291112008832 DTAP/Switch II; other site 291112008833 Switch I; other site 291112008834 ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035 291112008835 P loop; other site 291112008836 Nucleotide binding site [chemical binding]; other site 291112008837 DTAP/Switch II; other site 291112008838 Switch I; other site 291112008839 HMMPfam hit to PF02374, Anion-transporting ATPase, score 2.5e-16 291112008840 HMMSmart hit to SM00382, no description, score 0.023 291112008841 HMMPfam hit to PF02374, Anion-transporting ATPase, score 4.3e-108 291112008842 HMMSmart hit to SM00382, no description, score 4.9 291112008843 Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953 291112008844 HMMPfam hit to PF06953, Arsenical resistance operon trans-acting rep, score 5.4e-61 291112008845 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 291112008846 dimerization interface [polypeptide binding]; other site 291112008847 putative DNA binding site [nucleotide binding]; other site 291112008848 putative Zn2+ binding site [ion binding]; other site 291112008849 HMMSmart hit to SM00418, no description, score 1.9e-26 291112008850 HMMPfam hit to PF01022, Bacterial regulatory protein, arsR family, score 1.5e-16 291112008851 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 291112008852 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112008853 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112008854 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.1e-06 291112008855 1 probable transmembrane helix predicted for PAT3284 by TMHMM2.0 at aa 7-24 291112008856 type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844 291112008857 HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.00064 291112008858 HMMPfam hit to PF02321, Outer membrane efflux protein, score 0.0022 291112008859 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 291112008860 ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577 291112008861 FtsX-like permease family; Region: FtsX; pfam02687 291112008862 HMMPfam hit to PF02687, Predicted permease, score 6.2e-36 291112008863 4 probable transmembrane helices predicted for PAT3282 by TMHMM2.0 at aa 32-54, 276-298, 334-356 and 361-383 291112008864 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 291112008865 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 291112008866 Walker A/P-loop; other site 291112008867 ATP binding site [chemical binding]; other site 291112008868 Q-loop/lid; other site 291112008869 ABC transporter signature motif; other site 291112008870 Walker B; other site 291112008871 D-loop; other site 291112008872 H-loop/switch region; other site 291112008873 HMMSmart hit to SM00382, no description, score 1.1e-11 291112008874 HMMPfam hit to PF00005, ABC transporter, score 3.4e-43 291112008875 L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253 291112008876 homodimer interface [polypeptide binding]; other site 291112008877 homotetramer interface [polypeptide binding]; other site 291112008878 active site pocket [active] 291112008879 cleavage site 291112008880 HMMPfam hit to PF03576, Peptidase family T4, score 3.3e-117 291112008881 Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285 291112008882 L-idonate 5-dehydrogenase; Region: PLN02702 291112008883 inhibitor binding site; inhibition site 291112008884 catalytic Zn binding site [ion binding]; other site 291112008885 structural Zn binding site [ion binding]; other site 291112008886 NADP binding site [chemical binding]; other site 291112008887 tetramer interface [polypeptide binding]; other site 291112008888 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 3.2e-38 291112008889 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 8.5e-27 291112008890 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 291112008891 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 291112008892 conserved cys residue [active] 291112008893 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112008894 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 0.00029 291112008895 HMMSmart hit to SM00342, no description, score 7.1e-21 291112008896 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.7e-06 291112008897 HMMPfam hit to PF01965, DJ-1/PfpI family, score 4.1e-09 291112008898 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 291112008899 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139 291112008900 conserved cys residue [active] 291112008901 HMMPfam hit to PF01965, DJ-1/PfpI family, score 6.4e-15 291112008902 Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695 291112008903 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 291112008904 1 probable transmembrane helix predicted for PAT3274 by TMHMM2.0 at aa 5-27 291112008905 beta alanine--pyruvate transaminase; Provisional; Region: PRK09221 291112008906 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 291112008907 inhibitor-cofactor binding pocket; inhibition site 291112008908 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112008909 catalytic residue [active] 291112008910 HMMPfam hit to PF00202, Aminotransferase class-III, score 6.4e-142 291112008911 Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893 291112008912 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 291112008913 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112008914 catalytic residue [active] 291112008915 HMMPfam hit to PF00282, Pyridoxal-dependent decarboxylase conse, score 1.4e-09 291112008916 crotonyl-CoA reductase; Region: crot-CoA-red; TIGR01751 291112008917 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 291112008918 NAD(P) binding site [chemical binding]; other site 291112008919 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.1e-27 291112008920 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 2.2e-09 291112008921 12 probable transmembrane helices predicted for PAT3267 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 101-123, 146-165, 169-191, 216-238, 248-270, 283-305, 309-331, 344-366 and 371-393 291112008922 Methyltransferase domain; Region: Methyltransf_31; pfam13847 291112008923 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112008924 S-adenosylmethionine binding site [chemical binding]; other site 291112008925 HMMPfam hit to PF08241, Methyltransferase domain, score 1.6e-12 291112008926 HMMPfam hit to PF08242, Methyltransferase domain, score 7.7e-17 291112008927 Condensation domain; Region: Condensation; pfam00668 291112008928 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112008929 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112008930 acyl-activating enzyme (AAE) consensus motif; other site 291112008931 AMP binding site [chemical binding]; other site 291112008932 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112008933 alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561 291112008934 HMMPfam hit to PF00975, Thioesterase domain, score 4.2e-07 291112008935 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.5e-77 291112008936 HMMPfam hit to PF00668, Condensation domain, score 5.7e-07 291112008937 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 291112008938 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112008939 active site 291112008940 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 291112008941 Acyl transferase domain; Region: Acyl_transf_1; cl08282 291112008942 KR domain; Region: KR; pfam08659 291112008943 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 291112008944 NAD(P) binding site [chemical binding]; other site 291112008945 active site 291112008946 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112008947 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.1e-10 291112008948 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.6e-05 291112008949 HMMPfam hit to PF00698, Acyl transferase domain, score 3e-08 291112008950 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 5.3e-52 291112008951 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 2.9e-70 291112008952 Condensation domain; Region: Condensation; pfam00668 291112008953 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112008954 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112008955 acyl-activating enzyme (AAE) consensus motif; other site 291112008956 AMP binding site [chemical binding]; other site 291112008957 Condensation domain; Region: Condensation; pfam00668 291112008958 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112008959 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112008960 acyl-activating enzyme (AAE) consensus motif; other site 291112008961 AMP binding site [chemical binding]; other site 291112008962 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.1e-10 291112008963 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.5e-75 291112008964 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.3e-78 291112008965 HMMPfam hit to PF00668, Condensation domain, score 4.3e-08 291112008966 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 291112008967 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 291112008968 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.002 291112008969 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 291112008970 CoenzymeA binding site [chemical binding]; other site 291112008971 subunit interaction site [polypeptide binding]; other site 291112008972 PHB binding site; other site 291112008973 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112008974 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112008975 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112008976 acyl-activating enzyme (AAE) consensus motif; other site 291112008977 AMP binding site [chemical binding]; other site 291112008978 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112008979 Condensation domain; Region: Condensation; pfam00668 291112008980 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112008981 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112008982 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112008983 acyl-activating enzyme (AAE) consensus motif; other site 291112008984 AMP binding site [chemical binding]; other site 291112008985 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112008986 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.7e-13 291112008987 HMMPfam hit to PF00501, AMP-binding enzyme, score 6.1e-137 291112008988 HMMPfam hit to PF00668, Condensation domain, score 1.3e-62 291112008989 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.2e-16 291112008990 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.1e-157 291112008991 Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384 291112008992 hydroxyproline-2-epimerase; Provisional; Region: PRK13971 291112008993 HMMPfam hit to PF02567, Phenazine biosynthesis-like protein, score 1.4e-81 291112008994 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 291112008995 nucleoside/Zn binding site; other site 291112008996 dimer interface [polypeptide binding]; other site 291112008997 catalytic motif [active] 291112008998 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 8.5e-23 291112008999 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 291112009000 MarR family; Region: MarR; pfam01047 291112009001 HMMSmart hit to SM00347, no description, score 1e-16 291112009002 HMMPfam hit to PF01047, MarR family, score 8.6e-14 291112009003 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799 291112009004 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682 291112009005 Malonate decarboxylase gamma subunit (MdcE); Region: MdcE; cl17835 291112009006 HMMPfam hit to PF01039, Carboxyl transferase domain, score 1.4e-193 291112009007 Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase; cl00205 291112009008 helix swapped region; other site 291112009009 homodimer interface [polypeptide binding]; other site 291112009010 substrate binding pocket [chemical binding]; other site 291112009011 catalytic residues [active] 291112009012 NADH/NADPH cofactor binding site [chemical binding]; other site 291112009013 HMMPfam hit to PF00368, Hydroxymethylglutaryl-coenzyme A reductas, score 1.3e-28 291112009014 acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591 291112009015 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 291112009016 ATP-grasp domain; Region: ATP-grasp_4; cl17255 291112009017 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785 291112009018 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 2.6e-23 291112009019 HMMPfam hit to PF08443, RimK-like ATP-grasp domain, score 0.00087 291112009020 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 3.8e-86 291112009021 HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 1e-28 291112009022 Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511 291112009023 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 291112009024 carboxyltransferase (CT) interaction site; other site 291112009025 biotinylation site [posttranslational modification]; other site 291112009026 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 6.9e-11 291112009027 MmgE/PrpD family; Region: MmgE_PrpD; cl00912 291112009028 2-methylcitrate dehydratase; Region: prpD; TIGR02330 291112009029 HMMPfam hit to PF03972, MmgE/PrpD family, score 2.1e-43 291112009030 Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488 291112009031 pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372 291112009032 Protein of unknown function (DUF4255); Region: DUF4255; pfam14065 291112009033 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 291112009034 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112009035 Walker A motif; other site 291112009036 ATP binding site [chemical binding]; other site 291112009037 Walker B motif; other site 291112009038 arginine finger; other site 291112009039 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.1e-31 291112009040 HMMSmart hit to SM00382, no description, score 2.2e-12 291112009041 Adenoviral fibre protein (repeat/shaft region); Region: Adeno_shaft; pfam00608 291112009042 HMMPfam hit to PF00608, Adenoviral fibre protein (repeat/shaft re, score 9.1e-06 291112009043 Region 5 smaller 291112009044 conserved hypothetical protein, phage tail-like region; Region: TIGR02243 291112009045 Gene 25-like lysozyme; Region: GPW_gp25; pfam04965 291112009046 HMMPfam hit to PF04965, GPW / gp25 family, score 1.2e-33 291112009047 Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796 291112009048 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112009049 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841 291112009050 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112009051 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112009052 HMMPfam hit to PF04984, Phage tail sheath protein, score 8.5e-13 291112009053 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841 291112009054 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112009055 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112009056 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 2.5e-15 291112009057 indolepyruvate ferredoxin oxidoreductase; Validated; Region: PRK09193 291112009058 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 291112009059 dimer interface [polypeptide binding]; other site 291112009060 PYR/PP interface [polypeptide binding]; other site 291112009061 TPP binding site [chemical binding]; other site 291112009062 substrate binding site [chemical binding]; other site 291112009063 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 291112009064 TPP-binding site [chemical binding]; other site 291112009065 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014 291112009066 HMMPfam hit to PF01558, Pyruvate ferredoxin/flavodoxin oxidoreductas, score 2.1e-06 291112009067 Protein of unknown function (DUF2783); Region: DUF2783; pfam10932 291112009068 FAD-dependent oxidoreductase; Provisional; Region: PRK08132 291112009069 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 291112009070 HMMPfam hit to PF01494, FAD binding domain, score 4.1e-51 291112009071 EthD domain; Region: EthD; pfam07110 291112009072 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 291112009073 Old yellow enzyme (OYE)-related FMN binding domain, group 5. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_5_FMN; cd04747 291112009074 putative active site [active] 291112009075 putative FMN binding site [chemical binding]; other site 291112009076 putative substrate binding site [chemical binding]; other site 291112009077 putative catalytic residue [active] 291112009078 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 7.5e-74 291112009079 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK12825 291112009080 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 291112009081 NAD(P) binding site [chemical binding]; other site 291112009082 active site 291112009083 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.0008 291112009084 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.1e-21 291112009085 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112009086 putative substrate translocation pore; other site 291112009087 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112009088 14 probable transmembrane helices predicted for PAT3223 by TMHMM2.0 at aa 25-47, 62-84, 93-115, 119-138, 151-173, 178-197, 210-232, 237-259, 285-307, 317-336, 343-362, 377-399, 420-439 and 491-513 291112009089 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.5e-53 291112009090 Transglutaminase-like superfamily; Region: Transglut_core3; pfam13471 291112009091 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 291112009092 Ligand Binding Site [chemical binding]; other site 291112009093 Molecular Tunnel; other site 291112009094 HMMPfam hit to PF00733, Asparagine synthase, score 1.1e-05 291112009095 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 291112009096 ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228 291112009097 Walker A/P-loop; other site 291112009098 ATP binding site [chemical binding]; other site 291112009099 Q-loop/lid; other site 291112009100 ABC transporter signature motif; other site 291112009101 Walker B; other site 291112009102 D-loop; other site 291112009103 H-loop/switch region; other site 291112009104 4 probable transmembrane helices predicted for PAT3218 by TMHMM2.0 at aa 24-46, 53-75, 150-172 and 249-271 291112009105 HMMSmart hit to SM00382, no description, score 4.3e-18 291112009106 HMMPfam hit to PF00005, ABC transporter, score 3.4e-50 291112009107 PA-IL-like protein; Region: PA-IL; pfam07828 291112009108 HMMPfam hit to PF07828, PA-IL-like protein, score 4.7e-52 291112009109 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112009110 substrate binding pocket [chemical binding]; other site 291112009111 hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959 291112009112 membrane-bound complex binding site; other site 291112009113 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112009114 substrate binding pocket [chemical binding]; other site 291112009115 membrane-bound complex binding site; other site 291112009116 hinge residues; other site 291112009117 PAS domain; Region: PAS; smart00091 291112009118 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112009119 dimer interface [polypeptide binding]; other site 291112009120 phosphorylation site [posttranslational modification] 291112009121 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112009122 ATP binding site [chemical binding]; other site 291112009123 Mg2+ binding site [ion binding]; other site 291112009124 G-X-G motif; other site 291112009125 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112009126 active site 291112009127 phosphorylation site [posttranslational modification] 291112009128 intermolecular recognition site; other site 291112009129 dimerization interface [polypeptide binding]; other site 291112009130 Hpt domain; Region: Hpt; pfam01627 291112009131 HMMPfam hit to PF01627, Hpt domain, score 1.3e-06 291112009132 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.7e-24 291112009133 HMMSmart hit to SM00448, no description, score 1.1e-26 291112009134 HMMSmart hit to SM00387, no description, score 1e-29 291112009135 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 9.5e-34 291112009136 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.1e-14; HMMSmart hit to SM00388, no description, score 2.9e-12 291112009137 HMMPfam hit to PF08448, PAS fold, score 0.0014 291112009138 HMMSmart hit to SM00062, no description, score 5.4e-29 291112009139 HMMPfam hit to PF00497, Bacterial extracellular solute-binding p, score 5.5e-21 291112009140 HMMSmart hit to SM00062, no description, score 0.0028 291112009141 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112009142 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112009143 active site 291112009144 phosphorylation site [posttranslational modification] 291112009145 intermolecular recognition site; other site 291112009146 dimerization interface [polypeptide binding]; other site 291112009147 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112009148 DNA binding residues [nucleotide binding] 291112009149 dimerization interface [polypeptide binding]; other site 291112009150 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 2e-13; HMMSmart hit to SM00421, no description, score 1.6e-11 291112009151 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.8e-17 291112009152 HMMSmart hit to SM00448, no description, score 1.3e-13 291112009153 MASE1; Region: MASE1; cl17823 291112009154 10 probable transmembrane helices predicted for PAT3214 by TMHMM2.0 at aa 13-32, 37-56, 63-82, 87-109, 122-140, 155-177, 190-207, 217-234, 239-261 and 276-298 291112009155 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 291112009156 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112009157 Walker A motif; other site 291112009158 ATP binding site [chemical binding]; other site 291112009159 Walker B motif; other site 291112009160 arginine finger; other site 291112009161 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112009162 Walker A motif; other site 291112009163 ATP binding site [chemical binding]; other site 291112009164 Walker B motif; other site 291112009165 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 291112009166 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 2e-85 291112009167 HMMSmart hit to SM00382, no description, score 5.4e-12 291112009168 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 0.00034 291112009169 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 7.2e-09 291112009170 HMMSmart hit to SM00382, no description, score 2.2e-11 291112009171 HMMPfam hit to PF02861, Clp amino terminal domain, score 0.021 291112009172 type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348 291112009173 3 probable transmembrane helices predicted for PAT3212 by TMHMM2.0 at aa 7-29, 33-55 and 393-415 291112009174 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; cl01370 291112009175 1 probable transmembrane helix predicted for PAT3211 by TMHMM2.0 at aa 184-206 291112009176 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 291112009177 Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936 291112009178 HMMPfam hit to PF05936, Bacterial protein of unknown function (DUF87, score 1.2e-15 291112009179 Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790 291112009180 type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363 291112009181 ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812 291112009182 HMMPfam hit to PF06812, ImpA-related N-terminal, score 4.4e-23 291112009183 PAAR motif; Region: PAAR_motif; pfam05488 291112009184 HMMPfam hit to PF05488, PAAR motif, score 4.7e-08 291112009185 HMMPfam hit to PF05488, PAAR motif, score 0.0093 291112009186 HMMPfam hit to PF05488, PAAR motif, score 5.6 291112009187 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112009188 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112009189 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112009190 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 1.9e-45 291112009191 Protein of unknown function (DUF1305); Region: DUF1305; pfam06996 291112009192 HMMPfam hit to PF06996, Protein of unknown function (DUF1305), score 1.5e-36 291112009193 type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359 291112009194 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 291112009195 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 2.3e-114 291112009196 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 291112009197 HMMPfam hit to PF07025, Protein of unknown function (DUF1316), score 1.4e-08 291112009198 Protein of unknown function (DUF796); Region: DUF796; pfam05638 291112009199 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 2.4e-26 291112009200 type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355 291112009201 Protein of unknown function (DUF877); Region: DUF877; pfam05943 291112009202 HMMPfam hit to PF05943, Protein of unknown function (DUF877), score 4.6e-285 291112009203 Protein of unknown function (DUF770); Region: DUF770; pfam05591 291112009204 HMMPfam hit to PF05591, Protein of unknown function (DUF770), score 1.9e-55 291112009205 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112009206 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112009207 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 2.8e-39 291112009208 Phage Tail Collar Domain; Region: Collar; pfam07484 291112009209 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 2.8e-16 291112009210 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112009211 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 4e-39 291112009212 Phage Tail Collar Domain; Region: Collar; pfam07484 291112009213 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 7.6e-19 291112009214 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 291112009215 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112009216 Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210 291112009217 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112009218 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112009219 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112009220 Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829 291112009221 Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604 291112009222 beta-lactamase TEM; Provisional; Region: PRK15442 291112009223 Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354 291112009224 HMMPfam hit to PF00144, Beta-lactamase, score 2.7e-48 291112009225 1 probable transmembrane helix predicted for PAT3186 by TMHMM2.0 at aa 13-35 291112009226 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883 291112009227 nucleophilic elbow; other site 291112009228 catalytic triad; other site 291112009229 HMMPfam hit to PF01764, Lipase (class 3), score 4.7e-08 291112009230 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 0.00024 291112009231 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 2.2 291112009232 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 1 291112009233 HMMPfam hit to PF00353, Hemolysin-type calcium-binding repeat, score 1.1 291112009234 Protein of unknown function (DUF861); Region: Cupin_3; cl17594 291112009235 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 291112009236 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112009237 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 2.9e-07 291112009238 HMMSmart hit to SM00342, no description, score 1.4e-24 291112009239 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 291112009240 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 291112009241 N-terminal plug; other site 291112009242 ligand-binding site [chemical binding]; other site 291112009243 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 7.6e-20 291112009244 HMMPfam hit to PF00593, TonB dependent receptor, score 6e-23 291112009245 siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718 291112009246 muropeptide transporter; Validated; Region: ampG; cl17669 291112009247 12 probable transmembrane helices predicted for PAT3181 by TMHMM2.0 at aa 13-35, 50-67, 87-104, 109-127, 148-170, 174-196, 229-251, 261-283, 288-310, 320-342, 355-377 and 382-401 291112009248 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.2e-20 291112009249 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 291112009250 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112009251 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112009252 Walker A/P-loop; other site 291112009253 ATP binding site [chemical binding]; other site 291112009254 Q-loop/lid; other site 291112009255 ABC transporter signature motif; other site 291112009256 Walker B; other site 291112009257 D-loop; other site 291112009258 H-loop/switch region; other site 291112009259 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 4.7e-08 291112009260 6 probable transmembrane helices predicted for PAT3180 by TMHMM2.0 at aa 38-60, 80-102, 146-168, 173-195, 263-282 and 292-314 291112009261 HMMSmart hit to SM00382, no description, score 8.5e-17 291112009262 HMMPfam hit to PF00005, ABC transporter, score 1.1e-57 291112009263 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112009264 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112009265 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 291112009266 Walker A/P-loop; other site 291112009267 ATP binding site [chemical binding]; other site 291112009268 Q-loop/lid; other site 291112009269 ABC transporter signature motif; other site 291112009270 Walker B; other site 291112009271 D-loop; other site 291112009272 H-loop/switch region; other site 291112009273 6 probable transmembrane helices predicted for PAT3179 by TMHMM2.0 at aa 23-45, 55-74, 138-155, 159-178, 241-263 and 278-300 291112009274 HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 8.9e-05 291112009275 HMMSmart hit to SM00382, no description, score 7.4e-19 291112009276 HMMPfam hit to PF00005, ABC transporter, score 3.4e-64 291112009277 Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433 291112009278 Condensation domain; Region: Condensation; pfam00668 291112009279 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112009280 Nonribosomal peptide synthase; Region: NRPS; pfam08415 291112009281 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114 291112009282 acyl-activating enzyme (AAE) consensus motif; other site 291112009283 AMP binding site [chemical binding]; other site 291112009284 Methyltransferase domain; Region: Methyltransf_12; pfam08242 291112009285 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112009286 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112009287 Condensation domain; Region: Condensation; pfam00668 291112009288 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112009289 Nonribosomal peptide synthase; Region: NRPS; pfam08415 291112009290 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112009291 HMMPfam hit to PF00668, Condensation domain, score 2.6e-50 291112009292 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 3.8e-27 291112009293 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.5e-133 291112009294 HMMPfam hit to PF08242, Methyltransferase domain, score 9.4e-05 291112009295 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.5e-10 291112009296 HMMPfam hit to PF00668, Condensation domain, score 2.2e-48 291112009297 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 5.3e-28 291112009298 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112009299 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 291112009300 active site 291112009301 malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128 291112009302 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 291112009303 ketoreductase (KR) and fatty acid synthase (FAS), complex (x) SDRs; Region: KR_FAS_SDR_x; cd05274 291112009304 This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822 291112009305 NADP binding site [chemical binding]; other site 291112009306 active site 291112009307 Condensation domain; Region: Condensation; pfam00668 291112009308 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112009309 Nonribosomal peptide synthase; Region: NRPS; pfam08415 291112009310 Methyltransferase domain; Region: Methyltransf_23; pfam13489 291112009311 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112009312 S-adenosylmethionine binding site [chemical binding]; other site 291112009313 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112009314 Condensation domain; Region: Condensation; pfam00668 291112009315 Nonribosomal peptide synthase; Region: NRPS; pfam08415 291112009316 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114 291112009317 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112009318 acyl-activating enzyme (AAE) consensus motif; other site 291112009319 AMP binding site [chemical binding]; other site 291112009320 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112009321 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 291112009322 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 5.4e-75 291112009323 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 7.8e-74 291112009324 HMMPfam hit to PF00698, Acyl transferase domain, score 1.2e-49 291112009325 HMMPfam hit to PF00106, short chain dehydrogenase, score 6.9e-30 291112009326 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 3.8e-07 291112009327 HMMPfam hit to PF00668, Condensation domain, score 2.2e-26 291112009328 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 1.4e-25 291112009329 HMMPfam hit to PF08241, Methyltransferase domain, score 2e-08 291112009330 HMMPfam hit to PF08242, Methyltransferase domain, score 1.5e-22 291112009331 HMMPfam hit to PF00668, Condensation domain, score 8.3e-15 291112009332 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 1.1e-11 291112009333 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.8e-138 291112009334 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 6.9e-16 291112009335 HMMPfam hit to PF00975, Thioesterase domain, score 3e-24 291112009336 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693 291112009337 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 291112009338 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Rossm, score 2.6e-40 291112009339 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 291112009340 HMMPfam hit to PF00975, Thioesterase domain, score 1.1e-40 291112009341 Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021 291112009342 2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920 291112009343 acyl-activating enzyme (AAE) consensus motif; other site 291112009344 active site 291112009345 AMP binding site [chemical binding]; other site 291112009346 substrate binding site [chemical binding]; other site 291112009347 salicylate synthase; Region: salicyl_syn; TIGR03494 291112009348 chorismate binding enzyme; Region: Chorismate_bind; pfam00425 291112009349 HMMPfam hit to PF00501, AMP-binding enzyme, score 8.5e-105 291112009350 HMMPfam hit to PF00425, chorismate binding enzyme, score 1.1e-41 291112009351 Cupin; Region: Cupin_1; smart00835 291112009352 Cupin; Region: Cupin_1; smart00835 291112009353 HMMPfam hit to PF00190, Cupin, score 3.6e-17 291112009354 HMMPfam hit to PF07883, Cupin domain, score 2e-09 291112009355 HMMPfam hit to PF05899, Protein of unknown function (DUF861), score 0.0021 291112009356 HMMPfam hit to PF00190, Cupin, score 1.2e-19 291112009357 HMMPfam hit to PF07883, Cupin domain, score 3.4e-05 291112009358 1 probable transmembrane helix predicted for PAT3171 by TMHMM2.0 at aa 7-24 291112009359 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075 291112009360 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 291112009361 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112009362 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112009363 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 291112009364 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 291112009365 Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and vesicular transport]; Region: IcmF; COG3523 291112009366 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 291112009367 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 291112009368 3 probable transmembrane helices predicted for PAT3168 by TMHMM2.0 at aa 9-28, 43-65 and 353-375 291112009369 2 probable transmembrane helices predicted for PAT3167 by TMHMM2.0 at aa 19-41 and 46-68 291112009370 2 probable transmembrane helices predicted for PAT3165 by TMHMM2.0 at aa 6-28 and 48-70 291112009371 1 probable transmembrane helix predicted for PAT3164 by TMHMM2.0 at aa 7-26 291112009372 1 probable transmembrane helix predicted for PAT3163 by TMHMM2.0 at aa 7-26 291112009373 1 probable transmembrane helix predicted for PAT3162 by TMHMM2.0 at aa 7-24 291112009374 PGAP1-like protein; Region: PGAP1; pfam07819 291112009375 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 291112009376 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112009377 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112009378 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 291112009379 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 291112009380 1 probable transmembrane helix predicted for PAT3159 by TMHMM2.0 at aa 20-42 291112009381 Aspartyl protease; Region: Asp_protease_2; pfam13650 291112009382 Aspartyl protease; Region: Asp_protease_2; pfam13650 291112009383 inhibitor binding site; inhibition site 291112009384 catalytic motif [active] 291112009385 Catalytic residue [active] 291112009386 Active site flap [active] 291112009387 A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419 291112009388 putative active site [active] 291112009389 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112009390 ABC transporter signature motif; other site 291112009391 Walker B; other site 291112009392 D-loop; other site 291112009393 H-loop/switch region; other site 291112009394 HMMPfam hit to PF00005, ABC transporter, score 2.7e-11 291112009395 HMMPfam hit to PF03412, Peptidase C39 family, score 3.9e-45 291112009396 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 291112009397 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112009398 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 291112009399 active site 291112009400 OsmC-like protein; Region: OsmC; pfam02566 291112009401 HMMPfam hit to PF02566, OsmC-like protein, score 5e-33 291112009402 tyrosine transporter TyrP; Provisional; Region: PRK15132 291112009403 aromatic amino acid transport protein; Region: araaP; TIGR00837 291112009404 11 probable transmembrane helices predicted for PAT3149 by TMHMM2.0 at aa 7-29, 33-55, 81-103, 118-140, 145-167, 182-201, 214-236, 273-295, 307-329, 333-355 and 376-398 291112009405 HMMPfam hit to PF01490, Transmembrane amino acid transporter pro, score 0.00071 291112009406 HMMPfam hit to PF03222, Tryptophan/tyrosine permease family, score 2.8e-183 291112009407 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 291112009408 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112009409 catalytic residue [active] 291112009410 HMMPfam hit to PF00282, Pyridoxal-dependent decarboxylase conse, score 9.3e-08 291112009411 putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824 291112009412 PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276 291112009413 NAD(P) binding site [chemical binding]; other site 291112009414 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.7e-43 291112009415 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.4e-15 291112009416 Peptidase M60-like family; Region: M60-like; pfam13402 291112009417 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166 291112009418 This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a predicted...; Region: MopB_DmsA-EC; cd02770 291112009419 putative [Fe4-S4] binding site [ion binding]; other site 291112009420 putative molybdopterin cofactor binding site [chemical binding]; other site 291112009421 The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a predicted...; Region: MopB_CT_DmsA-EC; cd02794 291112009422 putative molybdopterin cofactor binding site; other site 291112009423 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 3.2e-36 291112009424 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 7.3e-73 291112009425 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 do, score 2.1e-07 291112009426 oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104 291112009427 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 291112009428 peptide binding site [polypeptide binding]; other site 291112009429 1 probable transmembrane helix predicted for PAT3142 by TMHMM2.0 at aa 7-26 291112009430 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 6.1e-87 291112009431 RES domain; Region: RES; smart00953 291112009432 PIN domain; Region: PIN_3; cl17397 291112009433 oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104 291112009434 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 291112009435 peptide binding site [polypeptide binding]; other site 291112009436 1 probable transmembrane helix predicted for PAT3137 by TMHMM2.0 at aa 9-28 291112009437 HMMPfam hit to PF00496, Bacterial extracellular solute-binding prot, score 1.9e-84 291112009438 Ubiquitin-like proteins; Region: UBQ; cl00155 291112009439 hydrophobic patch; other site 291112009440 Uncharacterized conserved protein [Function unknown]; Region: COG1262 291112009441 Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781 291112009442 HMMPfam hit to PF03781, Domain of unknown function (DUF323), score 3.1e-33 291112009443 FOG: WD40 repeat [General function prediction only]; Region: COG2319 291112009444 WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200 291112009445 structural tetrad; other site 291112009446 WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567 291112009447 structural tetrad; other site 291112009448 FOG: WD40 repeat [General function prediction only]; Region: COG2319 291112009449 HMMSmart hit to SM00320, no description, score 62 291112009450 HMMSmart hit to SM00320, no description, score 0.087 291112009451 HMMSmart hit to SM00320, no description, score 1 291112009452 HMMSmart hit to SM00320, no description, score 1.3e-07 291112009453 HMMPfam hit to PF00400, WD domain, G-beta repeat, score 1.5e-07 291112009454 HMMSmart hit to SM00320, no description, score 9.7e-06 291112009455 HMMPfam hit to PF00400, WD domain, G-beta repeat, score 8.4e-08 291112009456 HMMSmart hit to SM00320, no description, score 0.00021 291112009457 HMMPfam hit to PF00400, WD domain, G-beta repeat, score 0.0011 291112009458 HMMSmart hit to SM00320, no description, score 97 291112009459 GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641 291112009460 dimerization interface [polypeptide binding]; other site 291112009461 active site 291112009462 HMMPfam hit to PF00925, GTP cyclohydrolase II, score 1e-71 291112009463 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 291112009464 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 291112009465 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 8.6e-05 291112009466 ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496 291112009467 HMMPfam hit to PF06182, Protein of unknown function (DUF990), score 2.3e-06 291112009468 6 probable transmembrane helices predicted for PAT3131 by TMHMM2.0 at aa 21-43, 58-77, 119-141, 151-173, 194-216 and 226-248 291112009469 ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496 291112009470 HMMPfam hit to PF06182, Protein of unknown function (DUF990), score 6.5e-06 291112009471 5 probable transmembrane helices predicted for PAT3130 by TMHMM2.0 at aa 15-32, 52-71, 101-123, 130-152 and 213-235 291112009472 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 291112009473 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112009474 Walker A/P-loop; other site 291112009475 ATP binding site [chemical binding]; other site 291112009476 Q-loop/lid; other site 291112009477 ABC transporter signature motif; other site 291112009478 Walker B; other site 291112009479 D-loop; other site 291112009480 H-loop/switch region; other site 291112009481 HMMSmart hit to SM00382, no description, score 5.4e-08 291112009482 HMMPfam hit to PF00005, ABC transporter, score 1.8e-34 291112009483 phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754 291112009484 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 291112009485 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 2.4e-45 291112009486 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 3e-24 291112009487 Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365 291112009488 Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900 291112009489 putative active site [active] 291112009490 Fe(II) binding site [ion binding]; other site 291112009491 putative dimer interface [polypeptide binding]; other site 291112009492 putative tetramer interface [polypeptide binding]; other site 291112009493 HMMPfam hit to PF02900, Catalytic LigB subunit of aromatic ring-open, score 5.3e-82 291112009494 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200 291112009495 cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348 291112009496 NAD binding site [chemical binding]; other site 291112009497 active site 291112009498 HMMPfam hit to PF00106, short chain dehydrogenase, score 2e-08 291112009499 Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528 291112009500 [2Fe-2S] cluster binding site [ion binding]; other site 291112009501 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 3.2e-23 291112009502 Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667 291112009503 inter-subunit interface; other site 291112009504 HMMPfam hit to PF00866, Ring hydroxylating beta subunit, score 8.1e-59 291112009505 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 291112009506 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 291112009507 iron-sulfur cluster [ion binding]; other site 291112009508 [2Fe-2S] cluster binding site [ion binding]; other site 291112009509 C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881 291112009510 beta subunit interface [polypeptide binding]; other site 291112009511 alpha subunit interface [polypeptide binding]; other site 291112009512 active site 291112009513 substrate binding site [chemical binding]; other site 291112009514 Fe binding site [ion binding]; other site 291112009515 HMMPfam hit to PF00848, Ring hydroxylating alpha subunit (cat, score 1e-137 291112009516 HMMPfam hit to PF00355, Rieske [2Fe-2S] domain, score 5.6e-34 291112009517 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 291112009518 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112009519 The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450 291112009520 putative dimerization interface [polypeptide binding]; other site 291112009521 putative substrate binding pocket [chemical binding]; other site 291112009522 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.5e-21 291112009523 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.6e-36 291112009524 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 291112009525 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 291112009526 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 7.4e-31 291112009527 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 291112009528 HMMPfam hit to PF01689, Hydratase/decarboxylase, score 6e-110 291112009529 Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227 291112009530 HMMPfam hit to PF04227, Indigoidine synthase A like protein, score 1.4e-154 291112009531 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112009532 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112009533 acyl-activating enzyme (AAE) consensus motif; other site 291112009534 AMP binding site [chemical binding]; other site 291112009535 This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142 291112009536 NADPH bind site [chemical binding]; other site 291112009537 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112009538 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112009539 HMMPfam hit to PF00975, Thioesterase domain, score 3.3e-06 291112009540 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.6e-12 291112009541 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.3e-128 291112009542 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690 291112009543 nudix motif; other site 291112009544 HMMPfam hit to PF00293, NUDIX domain, score 7.3e-06 291112009545 Protein of unknown function (DUF4243); Region: DUF4243; pfam14027 291112009546 Protein of unknown function, DUF606; Region: DUF606; pfam04657 291112009547 5 probable transmembrane helices predicted for PAT3114 by TMHMM2.0 at aa 4-21, 34-56, 66-88, 93-115 and 120-137 291112009548 Protein of unknown function, DUF606; Region: DUF606; pfam04657 291112009549 5 probable transmembrane helices predicted for PAT3113 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 106-128 and 135-157 291112009550 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 291112009551 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112009552 motif II; other site 291112009553 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 4.1e-27 291112009554 4-oxalocrotonate tautomerase; Provisional; Region: PRK01271 291112009555 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112009556 active site 291112009557 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 0.0013 291112009558 fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161 291112009559 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 291112009560 ligand binding site [chemical binding]; other site 291112009561 flexible hinge region; other site 291112009562 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 291112009563 putative switch regulator; other site 291112009564 non-specific DNA interactions [nucleotide binding]; other site 291112009565 DNA binding site [nucleotide binding] 291112009566 sequence specific DNA binding site [nucleotide binding]; other site 291112009567 putative cAMP binding site [chemical binding]; other site 291112009568 HMMSmart hit to SM00100, no description, score 2.6e-23 291112009569 HMMPfam hit to PF00027, Cyclic nucleotide-binding domain, score 3.1e-20 291112009570 HMMSmart hit to SM00419, no description, score 2.2e-12 291112009571 HMMPfam hit to PF00325, Bacterial regulatory proteins, crp famil, score 1.8e-14 291112009572 universal stress protein UspE; Provisional; Region: PRK11175 291112009573 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 291112009574 Ligand Binding Site [chemical binding]; other site 291112009575 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 291112009576 Ligand Binding Site [chemical binding]; other site 291112009577 HMMPfam hit to PF00582, Universal stress protein family, score 8.8e-15 291112009578 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112009579 S-adenosylmethionine binding site [chemical binding]; other site 291112009580 HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 3.7e-05 291112009581 HMMPfam hit to PF08241, Methyltransferase domain, score 7e-29 291112009582 HMMPfam hit to PF08242, Methyltransferase domain, score 8.4e-16 291112009583 1 probable transmembrane helix predicted for PAT3105 by TMHMM2.0 at aa 101-123 291112009584 UreD urease accessory protein; Region: UreD; cl00530 291112009585 HMMPfam hit to PF01774, UreD urease accessory protein, score 9.5e-65 291112009586 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 291112009587 HMMPfam hit to PF02492, CobW/HypB/UreG, nucleotide-binding domain, score 8e-64 291112009588 Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830 291112009589 UreF; Region: UreF; pfam01730 291112009590 HMMPfam hit to PF01730, UreF, score 3.7e-32 291112009591 urease accessory protein UreE; Provisional; Region: ureE; PRK14711 291112009592 UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571 291112009593 dimer interface [polypeptide binding]; other site 291112009594 catalytic residues [active] 291112009595 HMMPfam hit to PF05194, UreE urease accessory protein, C-terminal do, score 0.0012 291112009596 HMMPfam hit to PF02814, UreE urease accessory protein, N-terminal do, score 6.5e-11 291112009597 urease subunit alpha; Reviewed; Region: ureC; PRK13309 291112009598 Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375 291112009599 subunit interactions [polypeptide binding]; other site 291112009600 active site 291112009601 flap region; other site 291112009602 HMMPfam hit to PF01979, Amidohydrolase family, score 2.1e-78 291112009603 HMMPfam hit to PF00449, Urease alpha-subunit, N-terminal domain, score 2.9e-82 291112009604 Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407 291112009605 gamma-beta subunit interface [polypeptide binding]; other site 291112009606 alpha-beta subunit interface [polypeptide binding]; other site 291112009607 HMMPfam hit to PF00699, Urease beta subunit, score 3.1e-64 291112009608 Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390 291112009609 alpha-gamma subunit interface [polypeptide binding]; other site 291112009610 beta-gamma subunit interface [polypeptide binding]; other site 291112009611 HMMPfam hit to PF00547, Urease, gamma subunit, score 1e-67 291112009612 High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376 291112009613 8 probable transmembrane helices predicted for PAT3096 by TMHMM2.0 at aa 7-26, 31-50, 71-93, 113-135, 186-208, 228-250, 262-284 and 304-326 291112009614 HMMPfam hit to PF03824, High-affinity nickel-transport protein, score 2.8e-115 291112009615 Predicted transcriptional regulator [Transcription]; Region: COG3905 291112009616 Nucleoside diphosphate kinases (NDP kinases, NDPks): NDP kinases, responsible for the synthesis of nucleoside triphosphates (NTPs), are involved in numerous regulatory processes associated with proliferation, development, and differentiation. They are...; Region: NDPk; cl00335 291112009617 AAA domain; Region: AAA_17; pfam13207 291112009618 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565 291112009619 classical (c) SDRs; Region: SDR_c; cd05233 291112009620 NAD(P) binding site [chemical binding]; other site 291112009621 active site 291112009622 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.6e-08 291112009623 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447 291112009624 nudix motif; other site 291112009625 HMMPfam hit to PF00293, NUDIX domain, score 1.2e-08 291112009626 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 291112009627 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 291112009628 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112009629 catalytic residue [active] 291112009630 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 5e-45 291112009631 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0038 291112009632 S-adenosylmethionine synthetase; Provisional; Region: PRK04439 291112009633 HMMPfam hit to PF01941, S-adenosylmethionine synthetase (AdoM, score 3.2e-64 291112009634 Carbamoyltransferase; Region: CmcH_NodU; pfam02543 291112009635 HMMPfam hit to PF02543, Carbamoyltransferase, score 7.6e-27 291112009636 Survival protein SurE; Region: SurE; pfam01975 291112009637 HMMPfam hit to PF01975, Survival protein SurE, score 1.6e-12 291112009638 Myo-inositol-1-phosphate synthase [Lipid metabolism]; Region: INO1; COG1260 291112009639 Myo-inositol-1-phosphate synthase; Region: NAD_binding_5; cl00554 291112009640 HMMPfam hit to PF07994, Myo-inositol-1-phosphate synthase, score 9e-62 291112009641 HMMPfam hit to PF01658, Myo-inositol-1-phosphate synthase, score 7.1e-35 291112009642 Region 6-1 291112009643 pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444 291112009644 NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233 291112009645 HMMPfam hit to PF02233, NAD(P) transhydrogenase beta subunit, score 0 291112009646 9 probable transmembrane helices predicted for PAT3081 by TMHMM2.0 at aa 4-26, 33-50, 55-74, 86-108, 121-143, 163-180, 185-207, 214-236 and 240-259 291112009647 NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424 291112009648 Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304 291112009649 ligand binding site [chemical binding]; other site 291112009650 homodimer interface [polypeptide binding]; other site 291112009651 NAD(P) binding site [chemical binding]; other site 291112009652 trimer interface B [polypeptide binding]; other site 291112009653 trimer interface A [polypeptide binding]; other site 291112009654 Domain of unknown function (DUF3814); Region: DUF3814; pfam12769 291112009655 5 probable transmembrane helices predicted for PAT3080 by TMHMM2.0 at aa 169-191, 399-418, 423-445, 452-471 and 476-498 291112009656 HMMPfam hit to PF01262, Alanine dehydrogenase/PNT, C-terminal dom, score 2.6e-87 291112009657 HMMPfam hit to PF05222, Alanine dehydrogenase/PNT, N-terminal dom, score 8.2e-71 291112009658 Protein of unknown function (DUF1471); Region: DUF1471; pfam07338 291112009659 Protein of unknown function (DUF1471); Region: DUF1471; pfam07338 291112009660 Protein of unknown function (DUF1471); Region: DUF1471; pfam07338 291112009661 HMMPfam hit to PF07338, Protein of unknown function (DUF1471), score 2.4e-07 291112009662 acyl carrier protein; Provisional; Region: acpP; PRK00982 291112009663 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 5e-15 291112009664 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK06816 291112009665 "initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827 291112009666 dimer interface [polypeptide binding]; other site 291112009667 active site 291112009668 HMMPfam hit to PF08541, 3-Oxoacyl-[acyl-carrier-protein (ACP)], score 6.7e-06 291112009669 1 probable transmembrane helix predicted for PAT3076 by TMHMM2.0 at aa 258-280 291112009670 transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905 291112009671 13 probable transmembrane helices predicted for PAT3075 by TMHMM2.0 at aa 5-24, 39-61, 90-112, 127-146, 159-178, 203-222, 235-257, 272-294, 331-350, 360-382, 389-406, 410-427 and 440-462 291112009672 HMMPfam hit to PF00324, Amino acid permease, score 4.1e-05 291112009673 putative transposase; Provisional; Region: PRK09857 291112009674 Putative transposase, YhgA-like; Region: Transposase_31; pfam04754 291112009675 HMMPfam hit to PF04754, Putative transposase, YhgA-like, score 8.6e-182 291112009676 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112009677 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 7.4e-05 291112009678 Fimbrial protein; Region: Fimbrial; cl01416 291112009679 HMMPfam hit to PF00419, Fimbrial protein, score 1.7e-39 291112009680 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 291112009681 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 291112009682 Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753 291112009683 1 probable transmembrane helix predicted for PAT3071 by TMHMM2.0 at aa 7-29 291112009684 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 1.1e-57 291112009685 HMMPfam hit to PF02753, Gram-negative pili assembly chaperone, score 1e-14 291112009686 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 291112009687 PapC N-terminal domain; Region: PapC_N; pfam13954 291112009688 Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577 291112009689 PapC C-terminal domain; Region: PapC_C; pfam13953 291112009690 1 probable transmembrane helix predicted for PAT3070 by TMHMM2.0 at aa 20-39 291112009691 HMMPfam hit to PF00577, Fimbrial Usher protein, score 0 291112009692 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112009693 1 probable transmembrane helix predicted for PAT3069 by TMHMM2.0 at aa 12-29 291112009694 HMMPfam hit to PF00419, Fimbrial protein, score 2.7e-05 291112009695 1 probable transmembrane helix predicted for PAT3068 by TMHMM2.0 at aa 7-24 291112009696 Protein of unknown function (DUF2778); Region: DUF2778; pfam10908 291112009697 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112009698 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 2.4e-41 291112009699 Domain of unknown function (DUF1902); Region: DUF1902; pfam08972 291112009700 ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131 291112009701 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112009702 ATP binding site [chemical binding]; other site 291112009703 putative Mg++ binding site [ion binding]; other site 291112009704 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112009705 nucleotide binding region [chemical binding]; other site 291112009706 ATP-binding site [chemical binding]; other site 291112009707 Helicase associated domain (HA2); Region: HA2; pfam04408 291112009708 Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717 291112009709 Domain of unknown function (DUF3418); Region: DUF3418; pfam11898 291112009710 HMMPfam hit to PF07717, Domain of unknown function (DUF1605), score 5.1e-19 291112009711 HMMPfam hit to PF04408, Helicase associated domain (HA2), score 3.6e-28 291112009712 HMMSmart hit to SM00490, no description, score 2.2e-14 291112009713 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.8e-12 291112009714 HMMSmart hit to SM00382, no description, score 1.7e-05 291112009715 HMMSmart hit to SM00487, no description, score 1.8e-26 291112009716 azoreductase; Reviewed; Region: PRK00170 291112009717 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 291112009718 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 0.00085 291112009719 HMMPfam hit to PF02525, Flavodoxin-like fold, score 3.1e-55 291112009720 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784 291112009721 HMMPfam hit to PF07027, Protein of unknown function (DUF1318), score 2.2e-50 291112009722 1 probable transmembrane helix predicted for PAT3060 by TMHMM2.0 at aa 7-26 291112009723 YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617 291112009724 hypothetical protein; Provisional; Region: PRK10695 291112009725 1 probable transmembrane helix predicted for PAT3058 by TMHMM2.0 at aa 9-31 291112009726 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 291112009727 D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183 291112009728 putative ligand binding site [chemical binding]; other site 291112009729 putative NAD binding site [chemical binding]; other site 291112009730 catalytic site [active] 291112009731 HMMPfam hit to PF00389, D-isomer specific 2-hydroxyacid dehydrog, score 1.7e-36 291112009732 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 4.6e-70 291112009733 heat-inducible protein; Provisional; Region: PRK10449 291112009734 HMMPfam hit to PF03724, Domain of unknown function (306), score 1.7e-24 291112009735 Flavodoxin-like fold; Region: Flavodoxin_2; cl00438 291112009736 hypothetical protein; Provisional; Region: PRK05170 291112009737 HMMPfam hit to PF05779, Bacterial protein of unknown function (DUF83, score 4.7e-99 291112009738 hypothetical protein; Provisional; Region: PRK10691 291112009739 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 291112009740 HMMPfam hit to PF01557, Fumarylacetoacetate (FAA) hydrolase fam, score 9e-73 291112009741 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100 291112009742 HMMPfam hit to PF05166, Family of unknown function (DUF709), score 6e-48 291112009743 septum formation inhibitor; Reviewed; Region: minC; PRK03511 291112009744 Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209 291112009745 Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775 291112009746 HMMPfam hit to PF05209, Septum formation inhibitor MinC, N-terminal, score 4.5e-38 291112009747 HMMPfam hit to PF03775, Septum formation inhibitor MinC, C-terminal, score 3.3e-57 291112009748 cell division inhibitor MinD; Provisional; Region: PRK10818 291112009749 Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036 291112009750 Switch I; other site 291112009751 Switch II; other site 291112009752 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.7e-28 291112009753 cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296 291112009754 HMMPfam hit to PF03776, Septum formation topological specificity fac, score 3.8e-49 291112009755 ribonuclease D; Provisional; Region: PRK10829 291112009756 DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142 291112009757 catalytic site [active] 291112009758 putative active site [active] 291112009759 putative substrate binding site [chemical binding]; other site 291112009760 HRDC domain; Region: HRDC; pfam00570 291112009761 HMMPfam hit to PF00570, HRDC domain, score 3.1e-20; HMMSmart hit to SM00341, no description, score 6.1e-15 291112009762 HMMPfam hit to PF01612, 3'-5' exonuclease, score 2e-54; HMMSmart hit to SM00474, no description, score 1.6e-42 291112009763 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974 291112009764 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112009765 Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936 291112009766 acyl-activating enzyme (AAE) consensus motif; other site 291112009767 putative AMP binding site [chemical binding]; other site 291112009768 putative active site [active] 291112009769 putative CoA binding site [chemical binding]; other site 291112009770 HMMPfam hit to PF00501, AMP-binding enzyme, score 2e-128 291112009771 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 291112009772 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112009773 Coenzyme A binding pocket [chemical binding]; other site 291112009774 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2e-19 291112009775 Outer membrane lipoprotein Slp family; Region: Slp; cl01164 291112009776 HMMPfam hit to PF03843, Outer membrane lipoprotein Slp family, score 2.7e-56 291112009777 1 probable transmembrane helix predicted for PAT3042 by TMHMM2.0 at aa 13-32 291112009778 tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725 291112009779 Glycoprotease family; Region: Peptidase_M22; pfam00814 291112009780 HMMPfam hit to PF00814, Glycoprotease family, score 3.6e-54 291112009781 CHAP domain; Region: CHAP; pfam05257 291112009782 HMMPfam hit to PF05257, CHAP domain, score 2.4e-15 291112009783 1 probable transmembrane helix predicted for PAT3040 by TMHMM2.0 at aa 5-24 291112009784 Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199 291112009785 DEAD/DEAH box helicase; Region: DEAD; pfam00270 291112009786 Helicase C-terminal domain; Region: Helicase_C_2; pfam13307 291112009787 HMMSmart hit to SM00491, no description, score 1.8e-54 291112009788 HMMSmart hit to SM00487, no description, score 0.0051 291112009789 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150 291112009790 homotrimer interaction site [polypeptide binding]; other site 291112009791 putative active site [active] 291112009792 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 5.7e-27 291112009793 1 probable transmembrane helix predicted for PAT3037 by TMHMM2.0 at aa 102-124 291112009794 multidrug efflux system protein MdtI; Provisional; Region: PRK10650 291112009795 4 probable transmembrane helices predicted for PAT3036 by TMHMM2.0 at aa 5-27, 40-57, 62-84 and 89-107 291112009796 HMMPfam hit to PF00893, Small Multidrug Resistance protein, score 1.2e-33 291112009797 multidrug efflux system protein MdtJ; Provisional; Region: PRK10452 291112009798 4 probable transmembrane helices predicted for PAT3035 by TMHMM2.0 at aa 2-19, 29-51, 56-78 and 82-101 291112009799 HMMPfam hit to PF00893, Small Multidrug Resistance protein, score 1.9e-27 291112009800 glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722 291112009801 Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479 291112009802 Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781 291112009803 HMMPfam hit to PF02781, Glucose-6-phosphate dehydrogenase, C-termina, score 1.3e-188 291112009804 HMMPfam hit to PF00479, Glucose-6-phosphate dehydrogenase, NAD bindi, score 8.3e-94 291112009805 DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302 291112009806 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 291112009807 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 291112009808 putative active site [active] 291112009809 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 6e-44 291112009810 HMMPfam hit to PF01380, SIS domain, score 2.7e-34 291112009811 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112009812 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112009813 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112009814 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112009815 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733 291112009816 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 1.3e-38 291112009817 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112009818 active site flap/lid [active] 291112009819 nucleophilic elbow; other site 291112009820 catalytic triad [active] 291112009821 HMMPfam hit to PF01764, Lipase (class 3), score 1.1e-21 291112009822 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 291112009823 Bacterial protein of unknown function (DUF879); Region: DUF879; cl15462 291112009824 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 8.7e-16 291112009825 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112009826 active site flap/lid [active] 291112009827 nucleophilic elbow; other site 291112009828 catalytic triad [active] 291112009829 HMMPfam hit to PF01764, Lipase (class 3), score 3.6e-23 291112009830 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250 291112009831 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 291112009832 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 291112009833 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-ter, score 7.8e-44 291112009834 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD b, score 4.5e-52 291112009835 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 0.0012 291112009836 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 291112009837 HMMPfam hit to PF00975, Thioesterase domain, score 4.3e-23 291112009838 Cupin-like domain; Region: Cupin_8; pfam13621 291112009839 pyruvate kinase; Provisional; Region: PRK05826 291112009840 Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342 291112009841 domain interfaces; other site 291112009842 active site 291112009843 HMMPfam hit to PF00224, Pyruvate kinase, barrel domain, score 1.9e-215 291112009844 HMMPfam hit to PF02887, Pyruvate kinase, alpha/beta domain, score 2.4e-54 291112009846 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 291112009847 5 probable transmembrane helices predicted for PAT3018 by TMHMM2.0 at aa 13-35, 276-298, 332-354, 369-391 and 420-442 291112009848 3 probable transmembrane helices predicted for PAT0810 by TMHMM2.0 at aa 172-194, 225-247 and 260-282 291112009849 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 291112009850 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112009851 1 probable transmembrane helix predicted for PAT0811 by TMHMM2.0 at aa 16-38 291112009852 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 291112009853 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 291112009854 Walker A/P-loop; other site 291112009855 ATP binding site [chemical binding]; other site 291112009856 Q-loop/lid; other site 291112009857 ABC transporter signature motif; other site 291112009858 Walker B; other site 291112009859 D-loop; other site 291112009860 H-loop/switch region; other site 291112009861 HMMSmart hit to SM00382, no description, score 3.8e-11 291112009862 HMMPfam hit to PF00005, ABC transporter, score 4.1e-67 291112009863 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112009864 anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942 291112009865 FeS/SAM binding site; other site 291112009866 radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085 291112009867 HMMPfam hit to PF04055, Radical SAM superfamily, score 6.4e-13 291112009868 Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279 291112009869 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984 291112009870 putative acyl-acceptor binding pocket; other site 291112009871 HMMPfam hit to PF03279, Bacterial lipid A biosynthesis acyltr, score 1.7e-122 291112009872 1 probable transmembrane helix predicted for PAT0814 by TMHMM2.0 at aa 26-44 291112009873 putative peptidase; Provisional; Region: PRK11649 291112009874 Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525 291112009875 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 291112009876 Peptidase family M23; Region: Peptidase_M23; pfam01551 291112009877 HMMPfam hit to PF01551, Peptidase family M23, score 8.8e-54 291112009878 HMMPfam hit to PF08525, Opacity-associated protein A N-terminal, score 1.1e-05 291112009879 high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545 291112009880 Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019 291112009881 metal binding site [ion binding]; metal-binding site 291112009882 high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544 291112009883 ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235 291112009884 ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108 291112009885 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112009886 putative PBP binding regions; other site 291112009887 ABC-ATPase subunit interface; other site 291112009888 HMMPfam hit to PF00950, ABC 3 transport family, score 1.4e-69 291112009889 region 19 291112009890 6 probable transmembrane helices predicted for PAT1814 by TMHMM2.0 at aa 15-37, 48-70, 90-112, 133-155, 175-197 and 202-219 291112009891 Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080 291112009892 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112009893 Walker A motif; other site 291112009894 ATP binding site [chemical binding]; other site 291112009895 Walker B motif; other site 291112009896 arginine finger; other site 291112009897 Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491 291112009898 HMMPfam hit to PF05491, Holliday junction DNA helicase ruvB C-termin, score 1.4e-52 291112009899 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.1e-34 291112009900 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 4.7e-05 291112009901 HMMSmart hit to SM00382, no description, score 1.5e-11 291112009902 HMMPfam hit to PF05496, Holliday junction DNA helicase ruvB N-termin, score 1.1e-25 291112009903 Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116 291112009904 RuvA N terminal domain; Region: RuvA_N; pfam01330 291112009905 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 291112009906 helix-hairpin-helix signature motif; other site 291112009907 RuvA, C-terminal domain; Region: RuvA_C; pfam07499 291112009908 HMMPfam hit to PF07499, RuvA, C-terminal domain, score 1.9e-17 291112009909 HMMSmart hit to SM00278, no description, score 0.069 291112009910 HMMSmart hit to SM00278, no description, score 0.054 291112009911 HMMPfam hit to PF01330, RuvA N terminal domain, score 3.6e-29 291112009912 Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529 291112009913 active site 291112009914 putative DNA-binding cleft [nucleotide binding]; other site 291112009915 dimer interface [polypeptide binding]; other site 291112009916 HMMPfam hit to PF02075, Crossover junction endodeoxyribonuclease Ruv, score 8.3e-97 291112009917 hypothetical protein; Validated; Region: PRK00110 291112009918 HMMPfam hit to PF01709, Domain of unknown function DUF28, score 1.8e-153 291112009919 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664 291112009920 nudix motif; other site 291112009921 HMMPfam hit to PF00293, NUDIX domain, score 1.1e-22 291112009922 aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476 291112009923 EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317 291112009924 dimer interface [polypeptide binding]; other site 291112009925 anticodon binding site; other site 291112009926 Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777 291112009927 homodimer interface [polypeptide binding]; other site 291112009928 motif 1; other site 291112009929 active site 291112009930 motif 2; other site 291112009931 GAD domain; Region: GAD; pfam02938 291112009932 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 291112009933 active site 291112009934 motif 3; other site 291112009935 HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 5.1e-219 291112009936 HMMPfam hit to PF02938, GAD domain, score 1.7e-47 291112009937 HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 0.0083 291112009938 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 1.9e-28 291112009939 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788 291112009940 3 probable transmembrane helices predicted for PAT1807 by TMHMM2.0 at aa 5-22, 71-89 and 102-124 291112009941 Methyltransferase domain; Region: Methyltransf_31; pfam13847 291112009942 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112009943 S-adenosylmethionine binding site [chemical binding]; other site 291112009944 HMMPfam hit to PF01739, CheR methyltransferase, SAM binding d, score 0.00024 291112009945 HMMPfam hit to PF08241, Methyltransferase domain, score 1e-17 291112009946 HMMPfam hit to PF08242, Methyltransferase domain, score 1.3e-14 291112009947 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112009948 S-adenosylmethionine binding site [chemical binding]; other site 291112009949 HMMPfam hit to PF08003, Protein of unknown function (DUF1698), score 6.4e-250 291112009950 HMMPfam hit to PF08241, Methyltransferase domain, score 2.2e-05 291112009951 HMMPfam hit to PF08242, Methyltransferase domain, score 2.5e-05 291112009952 copper homeostasis protein CutC; Provisional; Region: PRK11572 291112009953 HMMPfam hit to PF03932, CutC family, score 7.5e-98 291112009954 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268 291112009955 putative metal binding site [ion binding]; other site 291112009956 HMMPfam hit to PF06185, YecM protein, score 9e-97 291112009957 1 probable transmembrane helix predicted for PAT1801 by TMHMM2.0 at aa 7-29 291112009958 1 probable transmembrane helix predicted for PAT1800 by TMHMM2.0 at aa 12-34 291112009959 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112009960 active site flap/lid [active] 291112009961 nucleophilic elbow; other site 291112009962 catalytic triad [active] 291112009963 HMMPfam hit to PF01764, Lipase (class 3), score 5e-23 291112009964 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112009965 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112009966 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112009967 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112009968 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733 291112009969 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 2.2e-42 291112009970 1 probable transmembrane helix predicted for PAT1794 by TMHMM2.0 at aa 12-34 291112009971 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112009972 active site flap/lid [active] 291112009973 nucleophilic elbow; other site 291112009974 catalytic triad [active] 291112009975 HMMPfam hit to PF01764, Lipase (class 3), score 3e-25 291112009976 1 probable transmembrane helix predicted for PAT1792 by TMHMM2.0 at aa 24-46 291112009977 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112009978 active site flap/lid [active] 291112009979 nucleophilic elbow; other site 291112009980 catalytic triad [active] 291112009981 HMMPfam hit to PF01764, Lipase (class 3), score 3.2e-22 291112009982 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 291112009983 Bacterial protein of unknown function (DUF879); Region: DUF879; cl15462 291112009984 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 5.7e-16 291112009985 PAAR motif; Region: PAAR_motif; pfam05488 291112009986 HMMPfam hit to PF05488, PAAR motif, score 0.053 291112009987 HMMPfam hit to PF05488, PAAR motif, score 0.058 291112009988 hypothetical protein; Provisional; Region: PRK03757 291112009989 HMMPfam hit to PF04264, YceI like family, score 1.8e-73 291112009990 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 291112009991 HMMPfam hit to PF01292, Cytochrome b561 family, score 8e-57 291112009992 4 probable transmembrane helices predicted for PAT1784 by TMHMM2.0 at aa 13-35, 50-69, 90-112 and 146-168 291112009993 Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878 291112009994 HMMPfam hit to PF04199, Putative cyclase, score 8.4e-46 291112009995 Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018 291112009996 Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016 291112009997 catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671 291112009998 active site 291112009999 HIGH motif; other site 291112010000 KMSK motif region; other site 291112010001 Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956 291112010002 tRNA binding surface [nucleotide binding]; other site 291112010003 anticodon binding site; other site 291112010004 HMMPfam hit to PF03485, Arginyl tRNA synthetase N terminal do, score 7.3e-29 291112010005 HMMPfam hit to PF00750, tRNA synthetases class I (R), score 2.2e-198 291112010006 HMMPfam hit to PF05746, DALR anticodon binding domain, score 1.1e-50 291112010007 Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728 291112010008 MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123 291112010009 13 probable transmembrane helices predicted for PAT1780 by TMHMM2.0 at aa 26-45, 91-113, 128-150, 157-179, 184-203, 237-259, 274-291, 311-333, 353-375, 384-403, 407-429, 442-464 and 479-501 291112010010 HMMPfam hit to PF03023, MviN-like protein, score 6e-195 291112010011 ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809 291112010012 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 291112010013 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 6.9e-13 291112010014 multidrug resistance protein MdtH; Provisional; Region: PRK11646 291112010015 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112010016 putative substrate translocation pore; other site 291112010017 10 probable transmembrane helices predicted for PAT1778 by TMHMM2.0 at aa 13-35, 40-58, 78-95, 99-116, 136-158, 168-190, 211-233, 288-310, 335-357 and 367-384 291112010018 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.9e-49 291112010019 lipoprotein; Provisional; Region: PRK10598 291112010020 HMMPfam hit to PF07273, Protein of unknown function (DUF1439), score 1.1e-87 291112010021 Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381 291112010022 HMMPfam hit to PF06192, Cytoplasmic chaperone TorD, score 2.6e-21 291112010023 bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469 291112010024 Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164 291112010025 putative ligand binding site [chemical binding]; other site 291112010026 NAD binding site [chemical binding]; other site 291112010027 dimerization interface [polypeptide binding]; other site 291112010028 catalytic site [active] 291112010029 HMMPfam hit to PF02826, D-isomer specific 2-hydroxyacid dehydrog, score 1.1e-44 291112010030 Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422 291112010031 HMMPfam hit to PF05015, Plasmid maintenance system killer prot, score 4.8e-10 291112010032 Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093 291112010033 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112010034 non-specific DNA binding site [nucleotide binding]; other site 291112010035 salt bridge; other site 291112010036 sequence-specific DNA binding site [nucleotide binding]; other site 291112010037 HMMSmart hit to SM00530, no description, score 2e-06 291112010038 HMMPfam hit to PF01381, Helix-turn-helix, score 4.8e-08 291112010039 Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443 291112010040 HMMPfam hit to PF04443, Acyl-protein synthetase, LuxE, score 7.5e-246 291112010041 Alkanal monooxygenase are flavin monoxygenases. Molecular oxygen is activated by reaction with reduced flavin mononucleotide (FMNH2) and reacts with an aldehyde to yield the carboxylic acid, oxidized flavin (FMN) and a blue-green light. Bacterial...; Region: Alkanal_monooxygenase; cd01096 291112010042 Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296 291112010043 dimer interface [polypeptide binding]; other site 291112010044 non-prolyl cis peptide bond; other site 291112010045 active site 291112010046 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 1.7e-165 291112010047 Alkanal monooxygenase are flavin monoxygenases. Molecular oxygen is activated by reaction with reduced flavin mononucleotide (FMNH2) and reacts with an aldehyde to yield the carboxylic acid, oxidized flavin (FMN) and a blue-green light. Bacterial...; Region: Alkanal_monooxygenase; cd01096 291112010048 Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296 291112010049 dimer interface [polypeptide binding]; other site 291112010050 non-prolyl cis peptide bond; other site 291112010051 active site 291112010052 HMMPfam hit to PF00296, Luciferase-like monooxygenase, score 2.9e-197 291112010053 acyl transferase; Provisional; Region: luxD; PRK13604 291112010054 Acyl transferase; Region: Acyl_transf_2; pfam02273 291112010055 HMMPfam hit to PF02273, Acyl transferase, score 4.7e-221 291112010056 Acyl-CoA reductase LuxC; Region: ALDH_Acyl-CoA-Red_LuxC; cd07080 291112010057 Acyl-CoA reductase (LuxC); Region: LuxC; pfam05893 291112010058 putative catalytic cysteine [active] 291112010059 HMMPfam hit to PF05893, Acyl-CoA reductase (LuxC), score 0 291112010060 PAAR motif; Region: PAAR_motif; pfam05488 291112010061 S-type Pyocin; Region: Pyocin_S; pfam06958 291112010062 HMMPfam hit to PF06958, S-type Pyocin, score 6.3e-36 291112010063 HMMPfam hit to PF05488, PAAR motif, score 2e-08 291112010064 PAAR motif; Region: PAAR_motif; pfam05488 291112010065 S-type Pyocin; Region: Pyocin_S; pfam06958 291112010066 HMMPfam hit to PF06958, S-type Pyocin, score 8.2e-35 291112010067 HMMPfam hit to PF05488, PAAR motif, score 1.4e-08 291112010068 putative transporter; Provisional; Region: PRK11660 291112010069 Sulfate transporter family; Region: Sulfate_transp; pfam00916 291112010070 Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042 291112010071 HMMPfam hit to PF00860, Permease family, score 0.00019 291112010072 9 probable transmembrane helices predicted for PAT1761 by TMHMM2.0 at aa 51-73, 80-102, 117-139, 146-168, 222-244, 298-320, 335-357, 378-409 and 429-460 291112010073 HMMPfam hit to PF00916, Sulfate transporter family, score 4.4e-93 291112010074 HMMPfam hit to PF01740, STAS domain, score 1.6e-10 291112010075 DAHP synthetase I family; Region: DAHP_synth_1; pfam00793 291112010076 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198 291112010077 HMMPfam hit to PF00793, DAHP synthetase I family, score 3.3e-119 291112010078 hypothetical protein; Provisional; Region: PRK10941 291112010079 Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369 291112010080 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429 291112010081 binding surface 291112010082 TPR motif; other site 291112010083 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328 291112010084 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112010085 HMMPfam hit to PF05175, Methyltransferase small domain, score 1.2e-08 291112010086 HMMPfam hit to PF08242, Methyltransferase domain, score 8.4e-05 291112010087 peptide chain release factor 1; Validated; Region: prfA; PRK00591 291112010088 This domain is found in peptide chain release factors; Region: PCRF; smart00937 291112010089 RF-1 domain; Region: RF-1; pfam00472 291112010090 HMMPfam hit to PF00472, Peptidyl-tRNA hydrolase domain, score 3.6e-75 291112010091 HMMPfam hit to PF03462, PCRF domain, score 1.5e-73 291112010092 glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045 291112010093 NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213 291112010094 tRNA; other site 291112010095 putative tRNA binding site [nucleotide binding]; other site 291112010096 putative NADP binding site [chemical binding]; other site 291112010097 Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745 291112010098 HMMPfam hit to PF00745, Glutamyl-tRNAGlu reductase, dimerisation, score 1e-30 291112010099 HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 8.8e-69 291112010100 HMMPfam hit to PF05201, Glutamyl-tRNAGlu reductase, N-terminal d, score 4.9e-84 291112010101 outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022 291112010102 Outer membrane lipoprotein LolB; Region: LolB; pfam03550 291112010103 HMMPfam hit to PF03550, Outer membrane lipoprotein LolB, score 1.1e-74 291112010104 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343 291112010105 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 291112010106 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 291112010107 HMMPfam hit to PF00288, GHMP kinases N terminal domain, score 3e-17 291112010108 HMMPfam hit to PF08544, GHMP kinases C terminal, score 1.9e-07 291112010109 ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259 291112010110 N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793 291112010111 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112010112 active site 291112010113 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 1.4e-37 291112010114 hypothetical protein; Provisional; Region: PRK10692 291112010115 2 probable transmembrane helices predicted for PAT1752 by TMHMM2.0 at aa 7-29 and 42-64 291112010116 Bacterial Ig-like domain (group 1); Region: Big_1; cl17740 291112010117 HMMPfam hit to PF02369, Bacterial Ig-like domain (group 1), score 0.0045 291112010118 HMMSmart hit to SM00634, no description, score 0.0003 291112010119 Protein of unknown function (DUF3442); Region: DUF3442; pfam11924 291112010120 Bacterial Ig-like domain (group 1); Region: Big_1; cl17740 291112010121 Bacterial Ig-like domain (group 1); Region: Big_1; cl17740 291112010122 Bacterial Ig-like domain (group 1); Region: Big_1; cl17740 291112010123 HMMSmart hit to SM00634, no description, score 0.73 291112010124 HMMPfam hit to PF02369, Bacterial Ig-like domain (group 1), score 0.0049 291112010125 HMMSmart hit to SM00634, no description, score 0.0098 291112010126 HMMPfam hit to PF02369, Bacterial Ig-like domain (group 1), score 0.0051 291112010127 HMMSmart hit to SM00634, no description, score 0.0033 291112010128 HMMPfam hit to PF02369, Bacterial Ig-like domain (group 1), score 0.0029 291112010129 HMMSmart hit to SM00634, no description, score 0.00039 291112010130 HMMPfam hit to PF02369, Bacterial Ig-like domain (group 1), score 0.0023 291112010131 HMMSmart hit to SM00634, no description, score 0.00025 291112010132 HMMSmart hit to SM00634, no description, score 0.57 291112010133 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112010134 HMMPfam hit to PF03406, Phage tail fibre repeat, score 3.9e-05 291112010135 Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462 291112010136 putative active site [active] 291112010137 catalytic residue [active] 291112010138 HMMPfam hit to PF01195, Peptidyl-tRNA hydrolase, score 1.5e-97 291112010139 GTP-binding protein YchF; Reviewed; Region: PRK09601 291112010140 YchF GTPase; Region: YchF; cd01900 291112010141 G1 box; other site 291112010142 GTP/Mg2+ binding site [chemical binding]; other site 291112010143 Switch I region; other site 291112010144 G2 box; other site 291112010145 Switch II region; other site 291112010146 G3 box; other site 291112010147 G4 box; other site 291112010148 G5 box; other site 291112010149 TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867 291112010150 HMMPfam hit to PF01926, GTPase of unknown function, score 1.3e-30 291112010151 HMMPfam hit to PF06071, Protein of unknown function (DUF933), score 9.7e-61 291112010152 putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606 291112010153 HMMPfam hit to PF03693, Uncharacterised protein family (UPF0156), score 3.6e-11 291112010154 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 291112010155 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 291112010156 DNA-binding site [nucleotide binding]; DNA binding site 291112010157 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112010158 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112010159 homodimer interface [polypeptide binding]; other site 291112010160 catalytic residue [active] 291112010161 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.4e-07 291112010162 HMMPfam hit to PF00392, Bacterial regulatory proteins, gntR fam, score 8.9e-12 291112010163 HMMSmart hit to SM00345, no description, score 2.1e-11 291112010164 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654 291112010165 HMMPfam hit to PF01654, Bacterial Cytochrome Ubiquinol Oxidase, score 4.8e-232 291112010166 9 probable transmembrane helices predicted for PAT1735 by TMHMM2.0 at aa 20-42, 55-77, 97-119, 126-148, 186-208, 221-238, 324-346, 358-380 and 406-428 291112010167 Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322 291112010168 cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219 291112010169 cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219 291112010170 HMMPfam hit to PF02322, Cytochrome oxidase subunit II, score 2.4e-149 291112010171 8 probable transmembrane helices predicted for PAT1734 by TMHMM2.0 at aa 7-26, 74-96, 121-143, 158-180, 193-215, 230-249, 261-283 and 298-320 291112010172 nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600 291112010173 Histidine kinase; Region: HisKA_3; pfam07730 291112010174 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112010175 ATP binding site [chemical binding]; other site 291112010176 Mg2+ binding site [ion binding]; other site 291112010177 G-X-G motif; other site 291112010178 2 probable transmembrane helices predicted for PAT1733 by TMHMM2.0 at aa 15-34 and 41-58 291112010179 HMMPfam hit to PF07730, Histidine kinase, score 6.4e-12 291112010180 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 2e-18; HMMSmart hit to SM00387, no description, score 3.2e-08 291112010181 Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375 291112010182 Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193 291112010183 FAD binding pocket [chemical binding]; other site 291112010184 FAD binding motif [chemical binding]; other site 291112010185 phosphate binding motif [ion binding]; other site 291112010186 NAD binding pocket [chemical binding]; other site 291112010187 HMMPfam hit to PF08021, Siderophore-interacting FAD-binding dom, score 5.8e-53 291112010188 HMMPfam hit to PF04954, Siderophore-interacting protein, score 1.6e-46 291112010189 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112010190 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112010191 acyl-activating enzyme (AAE) consensus motif; other site 291112010192 AMP binding site [chemical binding]; other site 291112010193 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112010194 Condensation domain; Region: Condensation; pfam00668 291112010195 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112010196 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112010197 CoA binding site [chemical binding]; other site 291112010198 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112010199 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 7e-09 291112010200 HMMPfam hit to PF00668, Condensation domain, score 7.6e-18 291112010201 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 3.7e-07 291112010202 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.6e-153 291112010203 hypothetical protein; Provisional; Region: PRK10536 291112010204 HMMPfam hit to PF02562, PhoH-like protein, score 1.7e-126 291112010205 DNA-specific endonuclease I; Provisional; Region: PRK15137 291112010206 Endonuclease I; Region: Endonuclease_1; pfam04231 291112010207 HMMPfam hit to PF04231, Endonuclease I, score 3.4e-92 291112010208 1 probable transmembrane helix predicted for PAT1729 by TMHMM2.0 at aa 7-29 291112010209 phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340 291112010210 EamA-like transporter family; Region: EamA; pfam00892 291112010211 10 probable transmembrane helices predicted for PAT1728 by TMHMM2.0 at aa 4-23, 30-52, 56-78, 91-110, 114-136, 143-160, 175-194, 207-229, 233-255 and 262-279 291112010212 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.3e-08 291112010213 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.3e-07 291112010214 Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221 291112010215 classical (c) SDRs; Region: SDR_c; cd05233 291112010216 NAD(P) binding site [chemical binding]; other site 291112010217 active site 291112010218 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.8e-22 291112010219 Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020 291112010220 Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020 291112010221 Nucleoside diphosphate kinases (NDP kinases, NDPks): NDP kinases, responsible for the synthesis of nucleoside triphosphates (NTPs), are involved in numerous regulatory processes associated with proliferation, development, and differentiation. They are...; Region: NDPk; cl00335 291112010222 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112010223 S-adenosylmethionine binding site [chemical binding]; other site 291112010224 Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190 291112010225 Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194 291112010226 HMMSmart hit to SM00072, no description, score 0.00018 291112010227 HMMPfam hit to PF08241, Methyltransferase domain, score 1.8e-17 291112010228 HMMPfam hit to PF08242, Methyltransferase domain, score 1.3e-14 291112010229 Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333 291112010230 amphipathic channel; other site 291112010231 Asn-Pro-Ala signature motifs; other site 291112010232 6 probable transmembrane helices predicted for PAT1721 by TMHMM2.0 at aa 7-29, 33-55, 81-103, 130-152, 159-181 and 205-227 291112010233 HMMPfam hit to PF00230, Major intrinsic protein, score 5.8e-49 291112010234 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 291112010235 Ligand Binding Site [chemical binding]; other site 291112010236 HMMPfam hit to PF00582, Universal stress protein family, score 2.2e-15 291112010237 2 probable transmembrane helices predicted for PAT1718 by TMHMM2.0 at aa 21-43 and 75-97 291112010238 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 291112010239 Ligand Binding Site [chemical binding]; other site 291112010240 HMMPfam hit to PF00582, Universal stress protein family, score 6.5e-22 291112010241 response regulator; Provisional; Region: PRK09483 291112010242 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112010243 active site 291112010244 phosphorylation site [posttranslational modification] 291112010245 intermolecular recognition site; other site 291112010246 dimerization interface [polypeptide binding]; other site 291112010247 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112010248 DNA binding residues [nucleotide binding] 291112010249 dimerization interface [polypeptide binding]; other site 291112010250 HMMPfam hit to PF00072, Response regulator receiver domain, score 9e-37 291112010251 HMMSmart hit to SM00448, no description, score 5.4e-27 291112010252 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 2.5e-23; HMMSmart hit to SM00421, no description, score 1.3e-17 291112010253 excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558 291112010254 Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434 291112010255 GIY-YIG motif/motif A; other site 291112010256 active site 291112010257 catalytic site [active] 291112010258 putative DNA binding site [nucleotide binding]; other site 291112010259 metal binding site [ion binding]; metal-binding site 291112010260 UvrB/uvrC motif; Region: UVR; pfam02151 291112010261 UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459 291112010262 HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 7e-31 291112010263 HMMSmart hit to SM00465, no description, score 8.8e-24 291112010264 HMMPfam hit to PF02151, UvrB/uvrC motif, score 1.2e-10 291112010265 Region 18 291112010266 HMMPfam hit to PF08459, UvrC Helix-hairpin-helix N-terminal, score 3.2e-87 291112010267 HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 0.0061 291112010268 HMMSmart hit to SM00278, no description, score 0.88 291112010269 HMMSmart hit to SM00278, no description, score 44 291112010270 phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832 291112010271 4 probable transmembrane helices predicted for PAT1714 by TMHMM2.0 at aa 7-26, 30-52, 121-143 and 153-175 291112010272 HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 5.9e-44 291112010273 Tir chaperone protein (CesT) family; Region: CesT; pfam05932 291112010274 HMMPfam hit to PF05932, Tir chaperone protein (CesT), score 9.2e-11 291112010275 effector protein; Provisional; Region: PRK14052 291112010276 Fic/DOC family; Region: Fic; cl00960 291112010277 Domain of unknown function DUF29; Region: DUF29; pfam01724 291112010278 HMMPfam hit to PF01724, Domain of unknown function DUF29, score 8.3e-53 291112010279 PAS fold; Region: PAS_4; pfam08448 291112010280 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112010281 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112010282 DNA binding residues [nucleotide binding] 291112010283 dimerization interface [polypeptide binding]; other site 291112010284 HMMPfam hit to PF08448, PAS fold, score 0.00011 291112010285 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 5.6e-06; HMMSmart hit to SM00421, no description, score 0.00025 291112010286 PAS fold; Region: PAS_4; pfam08448 291112010287 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112010288 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112010289 DNA binding residues [nucleotide binding] 291112010290 dimerization interface [polypeptide binding]; other site 291112010291 HMMPfam hit to PF08448, PAS fold, score 1.9e-08 291112010292 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.2e-06; HMMSmart hit to SM00421, no description, score 0.00024 291112010293 PAS fold; Region: PAS_4; pfam08448 291112010294 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315 291112010295 DNA binding residues [nucleotide binding] 291112010296 dimerization interface [polypeptide binding]; other site 291112010297 HMMPfam hit to PF08448, PAS fold, score 5.9e-19 291112010298 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 5e-05 291112010299 PAS fold; Region: PAS_4; pfam08448 291112010300 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112010301 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112010302 DNA binding residues [nucleotide binding] 291112010303 dimerization interface [polypeptide binding]; other site 291112010304 HMMPfam hit to PF08448, PAS fold, score 2.4e-08 291112010305 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 6.1e-11; HMMSmart hit to SM00421, no description, score 1.9e-08 291112010306 PAS fold; Region: PAS_4; pfam08448 291112010307 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112010308 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112010309 DNA binding residues [nucleotide binding] 291112010310 dimerization interface [polypeptide binding]; other site 291112010311 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 2.8e-09 291112010312 HMMSmart hit to SM00421, no description, score 1.8e-07 291112010313 PAS fold; Region: PAS_4; pfam08448 291112010314 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112010315 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112010316 DNA binding residues [nucleotide binding] 291112010317 dimerization interface [polypeptide binding]; other site 291112010318 HMMPfam hit to PF08448, PAS fold, score 3.9e-08 291112010319 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.8e-05; HMMSmart hit to SM00421, no description, score 0.0019 291112010320 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 291112010321 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112010322 catalytic residue [active] 291112010323 Protein of unknown function; Region: YhfT; pfam10797 291112010324 12 probable transmembrane helices predicted for PAT1703 by TMHMM2.0 at aa 15-37, 58-80, 84-101, 108-130, 150-169, 174-196, 206-223, 259-281, 301-323, 330-352, 396-418 and 425-447 291112010325 Protein of unknown function DUF2620; Region: DUF2620; pfam10941 291112010326 Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530 291112010327 active site 291112010328 substrate binding pocket [chemical binding]; other site 291112010329 homodimer interaction site [polypeptide binding]; other site 291112010330 HMMPfam hit to PF02126, Phosphotriesterase family, score 1.5e-134 291112010331 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811 291112010332 dimer interface [polypeptide binding]; other site 291112010333 Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457 291112010334 active site 291112010335 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 291112010336 substrate binding site [chemical binding]; other site 291112010337 catalytic residue [active] 291112010338 HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 1.1e-12 291112010339 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432 291112010340 substrate binding pocket [chemical binding]; other site 291112010341 membrane-bound complex binding site; other site 291112010342 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112010343 active site 291112010344 DNA binding site [nucleotide binding] 291112010345 Int/Topo IB signature motif; other site 291112010346 HMMPfam hit to PF00589, Phage integrase family, score 2.2e-40 291112010347 PAS fold; Region: PAS_4; pfam08448 291112010348 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112010349 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112010350 DNA binding residues [nucleotide binding] 291112010351 dimerization interface [polypeptide binding]; other site 291112010352 HMMPfam hit to PF08448, PAS fold, score 1.1e-08 291112010353 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 4.4e-06; HMMSmart hit to SM00421, no description, score 8.2e-05 291112010354 PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410 291112010355 12 probable transmembrane helices predicted for PAT1693 by TMHMM2.0 at aa 7-29, 44-66, 98-115, 119-141, 148-170, 180-202, 223-245, 255-274, 314-336, 340-362, 369-391 and 395-417 291112010356 HMMPfam hit to PF04215, Putative sugar-specific permease, SgaT/UlaA, score 6.3e-127 291112010357 PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563 291112010358 active site 291112010359 P-loop; other site 291112010360 phosphorylation site [posttranslational modification] 291112010361 HMMPfam hit to PF02302, PTS system, Lactose/Cellobiose specific IIB, score 1.6e-27 291112010362 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 291112010363 active site 291112010364 phosphorylation site [posttranslational modification] 291112010365 HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosph, score 3.4e-46 291112010366 Transcriptional regulators [Transcription]; Region: PurR; COG1609 291112010367 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 291112010368 DNA binding site [nucleotide binding] 291112010369 domain linker motif; other site 291112010370 Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575 291112010371 putative ligand binding site [chemical binding]; other site 291112010372 putative dimerization interface [polypeptide binding]; other site 291112010373 HMMSmart hit to SM00354, no description, score 7.4e-27 291112010374 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 2.6e-07 291112010375 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 5.5e-05 291112010376 Rrf2 family protein; Region: rrf2_super; TIGR00738 291112010377 Transcriptional regulator; Region: Rrf2; pfam02082 291112010378 HMMPfam hit to PF02082, Transcriptional regulator, score 5e-43 291112010379 1 probable transmembrane helix predicted for PAT1688 by TMHMM2.0 at aa 12-34 291112010380 Ketosteroid isomerase-related protein [General function prediction only]; Region: COG3631 291112010381 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 291112010382 Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933 291112010383 FMN binding site [chemical binding]; other site 291112010384 active site 291112010385 substrate binding site [chemical binding]; other site 291112010386 catalytic residue [active] 291112010387 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 1.1e-83 291112010388 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 291112010389 putative active site [active] 291112010390 catalytic site [active] 291112010391 Putative catalytic domain, repeat 2, of Yersinia pestis murine toxin-like proteins; Region: PLDc_Ymt_2; cd09151 291112010392 PLD-like domain; Region: PLDc_2; pfam13091 291112010393 putative active site [active] 291112010394 catalytic site [active] 291112010395 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.13; HMMSmart hit to SM00155, no description, score 0.00058 291112010396 HMMSmart hit to SM00155, no description, score 0.002 291112010397 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 0.21 291112010398 D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine to pyruvate and ammonia. D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447 291112010399 Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291 291112010400 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112010401 catalytic residue [active] 291112010402 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.8e-49 291112010403 permease DsdX; Provisional; Region: PRK09921 291112010404 gluconate transporter; Region: gntP; TIGR00791 291112010405 HMMPfam hit to PF02447, GntP family permease, score 2.1e-222 291112010406 12 probable transmembrane helices predicted for PAT1683 by TMHMM2.0 at aa 4-23, 30-49, 54-76, 106-128, 143-165, 178-197, 226-248, 261-283, 303-322, 343-365, 385-407 and 420-442 291112010407 HMMPfam hit to PF03600, Citrate transporter, score 0.00063 291112010408 DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086 291112010409 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112010410 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 291112010411 dimerization interface [polypeptide binding]; other site 291112010412 substrate binding pocket [chemical binding]; other site 291112010413 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.3e-15 291112010414 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.3e-22 291112010415 Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254 291112010416 HMMPfam hit to PF06316, Enterobacterial Ail/Lom protein, score 8.1e-10 291112010417 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112010418 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 6.4e-38 291112010419 3 probable transmembrane helices predicted for PAT1680 by TMHMM2.0 at aa 20-37, 49-71 and 81-103 291112010420 D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049 291112010421 12 probable transmembrane helices predicted for PAT1679 by TMHMM2.0 at aa 21-43, 48-70, 93-115, 135-157, 164-186, 212-234, 255-277, 281-303, 342-364, 374-396, 408-430 and 440-459 291112010422 HMMPfam hit to PF00324, Amino acid permease, score 1.2e-145 291112010423 NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767 291112010424 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 291112010425 HMMPfam hit to PF03358, NADPH-dependent FMN reductase, score 0.0023 291112010426 HMMPfam hit to PF00258, Flavodoxin, score 5.9e-15 291112010427 Predicted symporter [General function prediction only]; Region: DhlC; COG4147 291112010428 Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475 291112010429 Na binding site [ion binding]; other site 291112010430 12 probable transmembrane helices predicted for PAT1677 by TMHMM2.0 at aa 36-58, 99-121, 160-182, 197-219, 224-246, 266-288, 309-331, 346-368, 405-424, 434-456, 461-478 and 483-505 291112010431 HMMPfam hit to PF00474, Sodium:solute symporter family, score 1.1e-181 291112010432 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809 291112010433 Predicted transcriptional regulator [Transcription]; Region: COG3905 291112010434 Proline dehydrogenase; Region: Pro_dh; pfam01619 291112010435 Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125 291112010436 Glutamate binding site [chemical binding]; other site 291112010437 NAD binding site [chemical binding]; other site 291112010438 catalytic residues [active] 291112010439 HMMPfam hit to PF01619, Proline dehydrogenase, score 6e-185 291112010440 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 8.7e-112 291112010441 flagella biosynthesis protein FliZ; Provisional; Region: PRK11582 291112010442 HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like d, score 0.0014 291112010443 flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986 291112010444 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 291112010445 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 291112010446 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 291112010447 DNA binding residues [nucleotide binding] 291112010448 HMMPfam hit to PF04545, Sigma-70, region, score 9.8e-20 291112010449 HMMPfam hit to PF08281, Sigma-70, region, score 5.2e-10 291112010450 HMMPfam hit to PF04539, Sigma-70 region, score 2.3e-16 291112010451 HMMPfam hit to PF04542, Sigma-70 region, score 2.9e-17 291112010452 flagellin; Validated; Region: PRK06819 291112010453 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 291112010454 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 291112010455 HMMPfam hit to PF00700, Bacterial flagellin C-terminus, score 6.3e-41 291112010456 HMMPfam hit to PF00669, Bacterial flagellin N-terminus, score 1.8e-77 291112010457 flagellar capping protein; Reviewed; Region: fliD; PRK08032 291112010458 Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465 291112010459 Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195 291112010460 HMMPfam hit to PF02465, Flagellar hook-associated protein, score 9.9e-31 291112010461 HMMPfam hit to PF07196, Flagellin hook IN motif, score 9.1e-10 291112010462 HMMPfam hit to PF07195, Flagellar hook-associated protein, score 8.4e-88 291112010463 flagellar protein FliS; Validated; Region: fliS; PRK05685 291112010464 HMMPfam hit to PF02561, Flagellar protein FliS, score 1.5e-43 291112010465 flagellar biosynthesis protein FliT; Provisional; Region: PRK10548 291112010466 HMMPfam hit to PF05400, Flagellar protein FliT, score 4.7e-44 291112010467 Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093 291112010468 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112010469 salt bridge; other site 291112010470 non-specific DNA binding site [nucleotide binding]; other site 291112010471 sequence-specific DNA binding site [nucleotide binding]; other site 291112010472 HMMPfam hit to PF01381, Helix-turn-helix, score 2.7e-05 291112010473 Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139 291112010474 HMMPfam hit to PF02049, Flagellar hook-basal body complex protein Fl, score 1.3e-27 291112010475 flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007 291112010476 Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514 291112010477 Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345 291112010478 HMMPfam hit to PF01514, Secretory protein of YscJ/FliF family, score 9.6e-89 291112010479 1 probable transmembrane helix predicted for PAT1667 by TMHMM2.0 at aa 28-47 291112010480 HMMPfam hit to PF08345, Flagellar M-ring protein C-terminal, score 6.1e-90 291112010481 flagellar motor switch protein G; Validated; Region: fliG; PRK05686 291112010482 FliG C-terminal domain; Region: FliG_C; pfam01706 291112010483 HMMPfam hit to PF01706, FliG C-terminal domain, score 8.8e-56 291112010484 flagellar assembly protein H; Validated; Region: fliH; PRK05687 291112010485 Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811 291112010486 Flagellar assembly protein FliH; Region: FliH; pfam02108 291112010487 HMMPfam hit to PF02108, Flagellar assembly protein FliH, score 2e-56 291112010488 flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960 291112010489 Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136 291112010490 Walker A motif/ATP binding site; other site 291112010491 Walker B motif; other site 291112010492 HMMPfam hit to PF02874, ATP synthase alpha/beta family, beta-ba, score 0.0025 291112010493 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleot, score 1.6e-119 291112010494 HMMSmart hit to SM00382, no description, score 1e-08 291112010495 flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689 291112010496 Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882 291112010497 HMMPfam hit to PF02050, Flagellar FliJ protein, score 1.8e-44 291112010498 Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144 291112010499 Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777 291112010500 HMMPfam hit to PF02120, Flagellar hook-length control protein, score 1.2e-31 291112010501 flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021 291112010502 flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07718 291112010503 HMMPfam hit to PF03748, Flagellar basal body-associated protein FliL, score 8.7e-28 291112010504 1 probable transmembrane helix predicted for PAT1661 by TMHMM2.0 at aa 37-59 291112010505 flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666 291112010506 Surface presentation of antigens (SPOA); Region: SpoA; pfam01052 291112010507 HMMPfam hit to PF02154, Flagellar motor switch protein FliM, score 1e-112 291112010508 flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963 291112010509 HMMPfam hit to PF01052, Surface presentation of antigens (SPOA) prot, score 3e-36 291112010510 flagellar biosynthesis protein FliO; Provisional; Region: PRK11486 291112010511 1 probable transmembrane helix predicted for PAT1658 by TMHMM2.0 at aa 35-57 291112010512 HMMPfam hit to PF04347, Flagellar biosynthesis protein, FliO, score 2.1e-27 291112010513 flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699 291112010514 5 probable transmembrane helices predicted for PAT1657 by TMHMM2.0 at aa 12-34, 54-76, 89-111, 191-213 and 220-242 291112010515 HMMPfam hit to PF00813, FliP family, score 1.9e-122 291112010516 flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700 291112010517 HMMPfam hit to PF01313, Bacterial export proteins, family, score 5.5e-37 291112010518 2 probable transmembrane helices predicted for PAT1656 by TMHMM2.0 at aa 15-37 and 50-72 291112010519 flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701 291112010520 HMMPfam hit to PF01311, Bacterial export proteins, family, score 1.3e-77 291112010521 6 probable transmembrane helices predicted for PAT1655 by TMHMM2.0 at aa 15-34, 41-63, 73-95, 128-150, 179-201 and 213-235 291112010522 Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_1; cd09996 291112010523 Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123 291112010524 active site 291112010525 Zn binding site [ion binding]; other site 291112010526 HMMPfam hit to PF00850, Histone deacetylase domain, score 8e-76 291112010527 Uncharacterized conserved protein [Function unknown]; Region: COG4104 291112010528 HMMPfam hit to PF05488, PAAR motif, score 2.6e-07 291112010529 HMMPfam hit to PF05488, PAAR motif, score 0.34 291112010530 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112010531 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112010532 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112010533 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112010534 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 5.5e-53 291112010535 flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027 291112010536 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 291112010537 HMMPfam hit to PF00669, Bacterial flagellin N-terminus, score 9.7e-09 291112010538 flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147 291112010539 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 291112010540 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855 291112010541 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 1.9e-12 291112010542 HMMPfam hit to PF00460, Flagella basal body rod protein, score 4e-09 291112010543 flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684 291112010544 Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951 291112010545 Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705 291112010546 HMMSmart hit to SM00047, no description, score 1.2e-40 291112010547 HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 1.1e-50 291112010548 flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303 291112010549 flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622 291112010550 HMMPfam hit to PF02119, Flagellar P-ring protein, score 1.6e-201 291112010551 1 probable transmembrane helix predicted for PAT1638 by TMHMM2.0 at aa 7-25 291112010552 flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249 291112010553 Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063 291112010554 HMMPfam hit to PF02107, Flagellar L-ring protein, score 1.5e-88 291112010555 flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693 291112010556 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 291112010557 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 291112010558 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 1.3e-20 291112010559 HMMPfam hit to PF00460, Flagella basal body rod protein, score 5.3e-15 291112010560 flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640 291112010561 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 291112010562 flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490 291112010563 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 0.0012 291112010564 HMMPfam hit to PF00460, Flagella basal body rod protein, score 9.4e-11 291112010565 flagellar hook protein FlgE; Validated; Region: flgE; PRK05682 291112010566 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 291112010567 Flagellar basal body protein FlaE; Region: FlaE; pfam07559 291112010568 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 291112010569 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 1.3e-18 291112010570 HMMPfam hit to PF07559, Flagellar basal body protein FlaE, score 1.1e-30 291112010571 Region 17 291112010572 HMMPfam hit to PF00460, Flagella basal body rod protein, score 1.4e-12 291112010573 flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655 291112010574 Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963 291112010575 FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861 291112010576 HMMPfam hit to PF03963, Flagellar hook capping protein, score 1.6e-37 291112010577 flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681 291112010578 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 291112010579 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 291112010580 HMMPfam hit to PF06429, Domain of unknown function (DUF1078), score 8.1e-06 291112010581 HMMPfam hit to PF00460, Flagella basal body rod protein, score 2e-09 291112010582 flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680 291112010583 flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182 291112010584 HMMPfam hit to PF00460, Flagella basal body rod protein, score 1.3e-10 291112010585 SAF-like; Region: SAF_2; pfam13144 291112010586 SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614 291112010587 Domains similar to fish antifreeze type III protein; Region: SAF; cl00555 291112010588 1 probable transmembrane helix predicted for PAT1630 by TMHMM2.0 at aa 7-29 291112010589 HMMPfam hit to PF03240, FlgA family, score 4.6e-51 291112010590 anti-sigma28 factor FlgM; Provisional; Region: PRK10810 291112010591 HMMPfam hit to PF04316, Anti-sigma-28 factor, FlgM, score 2.9e-20 291112010592 FlgN protein; Region: FlgN; cl09176 291112010593 HMMPfam hit to PF05130, FlgN protein, score 2.7e-24 291112010594 FG-GAP repeat; Region: FG-GAP_2; pfam14312 291112010595 FG-GAP repeat; Region: FG-GAP_2; pfam14312 291112010596 HMMSmart hit to SM00191, no description, score 5.2 291112010597 HMMSmart hit to SM00191, no description, score 84 291112010598 HMMSmart hit to SM00191, no description, score 22 291112010599 flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012 291112010600 FHIPEP family; Region: FHIPEP; pfam00771 291112010601 HMMPfam hit to PF00771, FHIPEP family, score 0 291112010602 7 probable transmembrane helices predicted for PAT1617 by TMHMM2.0 at aa 21-38, 42-64, 76-98, 113-135, 209-231, 251-273 and 294-316 291112010603 flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK12468 291112010604 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822 291112010605 HMMPfam hit to PF01312, FlhB HrpN YscU SpaS Family, score 3.5e-153 291112010606 4 probable transmembrane helices predicted for PAT1616 by TMHMM2.0 at aa 33-55, 94-116, 150-169 and 189-211 291112010607 PAAR motif; Region: PAAR_motif; pfam05488 291112010608 S-type Pyocin; Region: Pyocin_S; pfam06958 291112010609 HMMPfam hit to PF05488, PAAR motif, score 1.2e-07 291112010610 HMMPfam hit to PF05488, PAAR motif, score 16 291112010611 HMMPfam hit to PF06958, S-type Pyocin, score 7.2e-33 291112010612 Cupin domain; Region: Cupin_2; pfam07883 291112010613 HMMPfam hit to PF07883, Cupin domain, score 7.1e-10 291112010614 3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK06333 291112010615 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112010616 active site 291112010617 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 2.6e-76 291112010618 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 3.6e-91 291112010619 branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856 291112010620 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 291112010621 E3 interaction surface; other site 291112010622 lipoyl attachment site [posttranslational modification]; other site 291112010623 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 291112010624 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112010625 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.9e-07 291112010626 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 2.9e-13 291112010627 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071 291112010628 Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000 291112010629 tetramer interface [polypeptide binding]; other site 291112010630 TPP-binding site [chemical binding]; other site 291112010631 heterodimer interface [polypeptide binding]; other site 291112010632 phosphorylation loop region [posttranslational modification] 291112010633 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022 291112010634 Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410 291112010635 PYR/PP interface [polypeptide binding]; other site 291112010636 dimer interface [polypeptide binding]; other site 291112010637 TPP binding site [chemical binding]; other site 291112010638 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 291112010639 HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 3.6e-36 291112010640 HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 4.2e-36 291112010641 HMMPfam hit to PF00676, Dehydrogenase E1 component, score 1.8e-27 291112010642 Biofilm formation and stress response factor; Region: BsmA; pfam10014 291112010643 Condensation domain; Region: Condensation; pfam00668 291112010644 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112010645 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112010646 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112010647 acyl-activating enzyme (AAE) consensus motif; other site 291112010648 AMP binding site [chemical binding]; other site 291112010649 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112010650 Condensation domain; Region: Condensation; pfam00668 291112010651 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112010652 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112010653 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112010654 acyl-activating enzyme (AAE) consensus motif; other site 291112010655 AMP binding site [chemical binding]; other site 291112010656 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112010657 Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321 291112010658 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 291112010659 active site 291112010660 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 291112010661 Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826 291112010662 ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953 291112010663 putative NADP binding site [chemical binding]; other site 291112010664 KR domain; Region: KR; pfam08659 291112010665 active site 291112010666 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112010667 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 291112010668 PGAP1-like protein; Region: PGAP1; pfam07819 291112010669 HMMPfam hit to PF00668, Condensation domain, score 2.3e-47 291112010670 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.3e-119 291112010671 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.4e-13 291112010672 HMMPfam hit to PF00668, Condensation domain, score 5.5e-44 291112010673 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.3e-129 291112010674 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.6e-20 291112010675 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 1.2e-71 291112010676 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 8.4e-88 291112010677 HMMPfam hit to PF00698, Acyl transferase domain, score 3.7e-53 291112010678 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.4e-49 291112010679 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 0.0029 291112010680 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1e-12 291112010681 HMMPfam hit to PF00975, Thioesterase domain, score 5.5e-22 291112010682 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112010683 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112010684 putative substrate translocation pore; other site 291112010685 12 probable transmembrane helices predicted for PAT1606 by TMHMM2.0 at aa 20-42, 57-79, 91-108, 113-135, 148-170, 175-197, 231-253, 266-288, 295-314, 318-340, 353-375 and 385-407 291112010686 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1e-46 291112010687 Condensation domain; Region: Condensation; pfam00668 291112010688 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112010689 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112010690 acyl-activating enzyme (AAE) consensus motif; other site 291112010691 AMP binding site [chemical binding]; other site 291112010692 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112010693 HMMPfam hit to PF00668, Condensation domain, score 6.8e-31 291112010694 HMMPfam hit to PF00501, AMP-binding enzyme, score 8.9e-158 291112010695 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 4.4e-14 291112010696 SnoaL-like domain; Region: SnoaL_2; pfam12680 291112010697 chemotaxis regulator CheZ; Provisional; Region: PRK11166 291112010698 HMMPfam hit to PF04344, Chemotaxis phosphatase, CheZ, score 2.2e-107 291112010699 chemotaxis regulatory protein CheY; Provisional; Region: PRK10610 291112010700 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112010701 active site 291112010702 phosphorylation site [posttranslational modification] 291112010703 intermolecular recognition site; other site 291112010704 dimerization interface [polypeptide binding]; other site 291112010705 HMMPfam hit to PF00072, Response regulator receiver domain, score 3.5e-43 291112010706 HMMSmart hit to SM00448, no description, score 5.9e-36 291112010707 chemotaxis-specific methylesterase; Provisional; Region: PRK00742 291112010708 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112010709 active site 291112010710 phosphorylation site [posttranslational modification] 291112010711 intermolecular recognition site; other site 291112010712 dimerization interface [polypeptide binding]; other site 291112010713 CheB methylesterase; Region: CheB_methylest; pfam01339 291112010714 HMMPfam hit to PF01339, CheB methylesterase, score 1.1e-114 291112010715 HMMPfam hit to PF00072, Response regulator receiver domain, score 8.8e-19 291112010716 HMMSmart hit to SM00448, no description, score 2.7e-11 291112010717 chemotaxis methyltransferase CheR; Provisional; Region: PRK10611 291112010718 CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705 291112010719 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112010720 S-adenosylmethionine binding site [chemical binding]; other site 291112010721 HMMSmart hit to SM00138, no description, score 9.5e-105 291112010722 HMMPfam hit to PF01739, CheR methyltransferase, SAM binding domain, score 2.4e-87 291112010723 HMMPfam hit to PF03705, CheR methyltransferase, all-alpha domain, score 7.2e-14 291112010724 methyl-accepting protein IV; Provisional; Region: PRK09793 291112010725 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181 291112010726 dimer interface [polypeptide binding]; other site 291112010727 ligand binding site [chemical binding]; other site 291112010728 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 291112010729 dimerization interface [polypeptide binding]; other site 291112010730 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 291112010731 dimer interface [polypeptide binding]; other site 291112010732 putative CheW interface [polypeptide binding]; other site 291112010733 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 4.2e-111 291112010734 HMMSmart hit to SM00283, no description, score 3e-92 291112010735 HMMSmart hit to SM00304, no description, score 1.5e-08 291112010736 HMMPfam hit to PF00672, HAMP domain, score 1.2e-12 291112010737 2 probable transmembrane helices predicted for PAT1599 by TMHMM2.0 at aa 10-32 and 189-211 291112010738 HMMSmart hit to SM00319, no description, score 1.1e-22 291112010739 HMMPfam hit to PF02203, Tar ligand binding domain homologue, score 2.1e-23 291112010740 methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041 291112010741 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181 291112010742 dimer interface [polypeptide binding]; other site 291112010743 ligand binding site [chemical binding]; other site 291112010744 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 291112010745 dimerization interface [polypeptide binding]; other site 291112010746 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 291112010747 dimer interface [polypeptide binding]; other site 291112010748 putative CheW interface [polypeptide binding]; other site 291112010749 HMMPfam hit to PF00015, Methyl-accepting chemotaxis protein (MCP) s, score 3.1e-114 291112010750 HMMSmart hit to SM00283, no description, score 2.8e-95 291112010751 HMMSmart hit to SM00304, no description, score 7.4e-05 291112010752 HMMPfam hit to PF00672, HAMP domain, score 1.1e-10 291112010753 2 probable transmembrane helices predicted for PAT1598 by TMHMM2.0 at aa 7-29 and 193-215 291112010754 HMMSmart hit to SM00319, no description, score 7.1e-24 291112010755 HMMPfam hit to PF02203, Tar ligand binding domain homologue, score 2.1e-24 291112010756 purine-binding chemotaxis protein; Provisional; Region: PRK10612 291112010757 HMMPfam hit to PF01584, CheW-like domain, score 1.8e-32 291112010758 HMMSmart hit to SM00260, no description, score 4.4e-41 291112010759 chemotaxis protein CheA; Provisional; Region: PRK10547 291112010760 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 291112010761 putative binding surface; other site 291112010762 active site 291112010763 CheY binding; Region: CheY-binding; pfam09078 291112010764 Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895 291112010765 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112010766 ATP binding site [chemical binding]; other site 291112010767 Mg2+ binding site [ion binding]; other site 291112010768 G-X-G motif; other site 291112010769 CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731 291112010770 HMMSmart hit to SM00260, no description, score 1.3e-41 291112010771 HMMPfam hit to PF01584, CheW-like domain, score 1e-28 291112010772 HMMSmart hit to SM00387, no description, score 2.3e-23 291112010773 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 1.2e-23 291112010774 HMMPfam hit to PF01627, Hpt domain, score 2.4e-18 291112010775 HMMSmart hit to SM00073, no description, score 1e-32 291112010776 flagellar motor protein MotB; Validated; Region: motB; PRK09041 291112010777 Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677 291112010778 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 291112010779 ligand binding site [chemical binding]; other site 291112010780 HMMPfam hit to PF00691, OmpA family, score 6.1e-23 291112010781 1 probable transmembrane helix predicted for PAT1595 by TMHMM2.0 at aa 23-45 291112010782 Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291 291112010783 flagellar motor protein MotA; Validated; Region: PRK09110 291112010784 4 probable transmembrane helices predicted for PAT1594 by TMHMM2.0 at aa 2-24, 34-51, 171-190 and 205-227 291112010785 transcriptional activator FlhC; Provisional; Region: PRK12722 291112010786 HMMPfam hit to PF05280, Flagellar transcriptional activator (FlhC), score 7.6e-152 291112010787 transcriptional activator FlhD; Provisional; Region: PRK02909 291112010788 HMMPfam hit to PF05247, Flagellar transcriptional activator (FlhD), score 2.8e-67 291112010789 magnesium-transporting ATPase; Provisional; Region: PRK15122 291112010790 1 probable transmembrane helix predicted for PAT1590 by TMHMM2.0 at aa 7-29 291112010791 magnesium transport protein MgtC; Provisional; Region: PRK15385 291112010792 MgtC family; Region: MgtC; pfam02308 291112010793 HMMPfam hit to PF02308, MgtC family, score 1.4e-70 291112010794 4 probable transmembrane helices predicted for PAT1856 by TMHMM2.0 at aa 4-26, 39-58, 62-81 and 94-116 291112010795 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 291112010796 DNA-binding site [nucleotide binding]; DNA binding site 291112010797 RNA-binding motif; other site 291112010798 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 7.6e-44 291112010799 HMMSmart hit to SM00357, no description, score 2.8e-31 291112010800 sigma70 family sigma factor YlaC; Region: YlaC; pfam10777 291112010801 2 probable transmembrane helices predicted for PAT1587 by TMHMM2.0 at aa 31-53 and 58-80 291112010802 Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294 291112010803 active site 291112010804 substrate binding pocket [chemical binding]; other site 291112010805 dimer interface [polypeptide binding]; other site 291112010806 1 probable transmembrane helix predicted for PAT1584 by TMHMM2.0 at aa 13-35 291112010807 HMMPfam hit to PF01979, Amidohydrolase family, score 1.1e-62 291112010808 biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301 291112010809 colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411 291112010810 cheY-homologous receiver domain; Region: REC; smart00448 291112010811 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112010812 DNA binding residues [nucleotide binding] 291112010813 dimerization interface [polypeptide binding]; other site 291112010814 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 1.9e-07; HMMSmart hit to SM00421, no description, score 6.7e-06 291112010815 putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142 291112010816 Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518 291112010817 active site residue [active] 291112010818 HMMSmart hit to SM00450, no description, score 1.6e-27 291112010819 HMMPfam hit to PF00581, Rhodanese-like domain, score 1.8e-28 291112010820 DinI-like family; Region: DinI; cl11630 291112010821 HMMPfam hit to PF06183, DinI-like family, score 1.3e-26 291112010822 Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279 291112010823 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984 291112010824 putative acyl-acceptor binding pocket; other site 291112010825 HMMPfam hit to PF03279, Bacterial lipid A biosynthesis acyltr, score 9.8e-128 291112010826 1 probable transmembrane helix predicted for PAT1579 by TMHMM2.0 at aa 20-42 291112010827 dipeptide/tripeptide permease B; Provisional; Region: PRK10207 291112010828 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112010829 putative substrate translocation pore; other site 291112010830 POT family; Region: PTR2; cl17359 291112010831 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-16 291112010832 14 probable transmembrane helices predicted for PAT1578 by TMHMM2.0 at aa 34-51, 61-83, 92-114, 119-141, 154-176, 181-203, 234-256, 260-282, 294-311, 337-359, 371-393, 413-435, 442-464 and 479-501 291112010833 HMMPfam hit to PF00854, POT family, score 4.9e-50 291112010834 Cupin domain; Region: Cupin_2; cl17218 291112010835 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 291112010836 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112010837 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 1.4e-07 291112010838 HMMSmart hit to SM00342, no description, score 1.6e-24 291112010839 tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798 291112010840 dimer interface [polypeptide binding]; other site 291112010841 putative tRNA-binding site [nucleotide binding]; other site 291112010842 HMMPfam hit to PF01588, Putative tRNA binding domain, score 5.7e-22 291112010843 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 291112010844 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 291112010845 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 291112010846 putative active site [active] 291112010847 HMMPfam hit to PF01380, SIS domain, score 7.4e-37 291112010848 HMMPfam hit to PF01418, Helix-turn-helix domain, rpiR family, score 5.5e-06 291112010849 Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085 291112010850 methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722 291112010851 tetrameric interface [polypeptide binding]; other site 291112010852 NAD binding site [chemical binding]; other site 291112010853 catalytic residues [active] 291112010854 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 1.3e-165 291112010855 Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962 291112010856 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 291112010857 PYR/PP interface [polypeptide binding]; other site 291112010858 dimer interface [polypeptide binding]; other site 291112010859 TPP binding site [chemical binding]; other site 291112010860 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 291112010861 Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003 291112010862 TPP-binding site; other site 291112010863 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 2.9e-08 291112010864 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 2e-38 291112010865 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 3.8e-52 291112010866 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 291112010867 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 291112010868 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 291112010869 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 6.6e-19 291112010870 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 5.3e-07 291112010871 putative transporter; Provisional; Region: PRK10484 291112010872 uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328 291112010873 Na binding site [ion binding]; other site 291112010874 15 probable transmembrane helices predicted for PAT1570 by TMHMM2.0 at aa 5-24, 37-59, 74-96, 121-143, 163-185, 197-216, 243-265, 285-307, 327-349, 379-401, 411-430, 442-460, 464-486, 507-526 and 531-550 291112010875 HMMPfam hit to PF00474, Sodium:solute symporter family, score 1e-33 291112010876 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 291112010877 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 291112010878 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 3.6e-36 291112010879 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 0.00012 291112010880 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 291112010881 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 291112010882 substrate binding site [chemical binding]; other site 291112010883 ATP binding site [chemical binding]; other site 291112010884 Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863 291112010885 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892 291112010886 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 3e-43 291112010887 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 291112010888 AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060 291112010889 DNA interaction; other site 291112010890 Metal-binding active site; metal-binding site 291112010891 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 3.7e-49 291112010892 HMMPfam hit to PF01261, Xylose isomerase-like TIM barrel, score 1.7e-08 291112010893 Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718 291112010894 HMMPfam hit to PF06845, Myo-inositol catabolism protein IolB, score 3.6e-167 291112010895 CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cd09739 291112010896 CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cd09737 291112010897 CRISPR/Cas system-associated RAMP superfamily protein Csy2; Region: Csy2_I-F; cd09736 291112010898 CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cd09735 291112010899 CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-F; cd09718 291112010900 1 probable transmembrane helix predicted for PAT1561 by TMHMM2.0 at aa 235-257 291112010901 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112010902 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 1.4e-59 291112010903 3 probable transmembrane helices predicted for PAT1560 by TMHMM2.0 at aa 9-31, 46-68 and 81-100 291112010904 2 probable transmembrane helices predicted for PAT1559 by TMHMM2.0 at aa 190-212 and 254-276 291112010905 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643 291112010906 Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778 291112010907 TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029 291112010908 active site 291112010909 metal binding site [ion binding]; metal-binding site 291112010910 interdomain interaction site; other site 291112010911 D5 N terminal like; Region: D5_N; smart00885 291112010912 phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613 291112010913 Poxvirus D5 protein-like; Region: Pox_D5; pfam03288 291112010914 HMMPfam hit to PF03288, Poxvirus D5 protein-like, score 6.4e-113 291112010915 HMMPfam hit to PF08273, Zinc-binding domain of primase-helicas, score 4.3e-13 291112010916 AntA/AntB antirepressor; Region: AntA; pfam08346 291112010917 HMMPfam hit to PF08346, AntA/AntB antirepressor, score 4.3e-31 291112010918 integrase; Provisional; Region: PRK09692 291112010919 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 291112010920 active site 291112010921 Int/Topo IB signature motif; other site 291112010922 HMMPfam hit to PF00589, Phage integrase family, score 2.3e-27 291112010923 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920 291112010924 sulfur relay protein, TusE/DsrC/DsvC family; Region: dsrC_tusE_dsvC; TIGR03342 291112010925 1 probable transmembrane helix predicted for PAT1552 by TMHMM2.0 at aa 13-32 291112010926 HMMPfam hit to PF04358, DsrC like protein, score 8.4e-74 291112010927 Acylphosphatase; Region: Acylphosphatase; cl00551 291112010928 HMMPfam hit to PF00708, Acylphosphatase, score 5e-08 291112010929 heat shock protein HspQ; Provisional; Region: PRK14129 291112010930 CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cd09735 291112010931 CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673 291112010932 CRISPR-associated helicase Cas3, subtype I-F/YPEST; Region: cas3_yersinia; TIGR02562 291112010933 CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656 291112010934 CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656 291112010935 Predicted CoA-binding protein [General function prediction only]; Region: COG1832 291112010936 HMMPfam hit to PF02629, CoA binding domain, score 8.9e-17 291112010937 Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422 291112010938 active site 291112010939 dimer interfaces [polypeptide binding]; other site 291112010940 catalytic residues [active] 291112010941 HMMPfam hit to PF02142, MGS-like domain, score 6.1e-28 291112010942 DNA helicase IV; Provisional; Region: helD; PRK11054 291112010943 DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462 291112010944 Part of AAA domain; Region: AAA_19; pfam13245 291112010945 Family description; Region: UvrD_C_2; pfam13538 291112010946 HMMPfam hit to PF00580, UvrD/REP helicase, score 1.6e-09 291112010947 TIGR01666 family membrane protein; Region: YCCS 291112010948 FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805 291112010949 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 291112010950 HMMPfam hit to PF05976, Bacterial membrane protein of unknown functi, score 0 291112010951 9 probable transmembrane helices predicted for PAT1543 by TMHMM2.0 at aa 15-37, 69-88, 92-111, 118-140, 144-166, 441-460, 465-482, 487-506 and 516-535 291112010952 TfoX N-terminal domain; Region: TfoX_N; pfam04993 291112010953 TfoX C-terminal domain; Region: TfoX_C; pfam04994 291112010954 HMMPfam hit to PF04994, TfoX C-terminal domain, score 4.7e-21 291112010955 HMMPfam hit to PF04993, TfoX N-terminal domain, score 3.4e-15 291112010956 SOS cell division inhibitor; Provisional; Region: PRK10595 291112010957 HMMPfam hit to PF03846, Cell division inhibitor SulA, score 1.3e-36 291112010958 outer membrane protein A; Reviewed; Region: PRK10808 291112010959 OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389 291112010960 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 291112010961 ligand binding site [chemical binding]; other site 291112010962 HMMPfam hit to PF01389, OmpA-like transmembrane domain, score 2.1e-111 291112010963 HMMPfam hit to PF00691, OmpA family, score 8.1e-35 291112010964 Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097 291112010965 HMMPfam hit to PF06303, Protein of unknown function (DUF1047), score 2e-110 291112010966 Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067 291112010967 Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362 291112010968 FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287 291112010969 active site 1 [active] 291112010970 dimer interface [polypeptide binding]; other site 291112010971 active site 2 [active] 291112010972 HMMPfam hit to PF07977, FabA-like domain, score 5.9e-80 291112010973 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009 291112010974 Protein of unknown function (DUF330); Region: DUF330; pfam03886 291112010975 HMMPfam hit to PF03886, Protein of unknown function (DUF330), score 1.9e-49 291112010976 paraquat-inducible protein B; Provisional; Region: PRK10807 291112010977 mce related protein; Region: MCE; pfam02470 291112010978 mce related protein; Region: MCE; pfam02470 291112010979 mce related protein; Region: MCE; pfam02470 291112010980 HMMPfam hit to PF02470, mce related protein, score 3.3e-19 291112010981 HMMPfam hit to PF02470, mce related protein, score 0.00054 291112010982 HMMPfam hit to PF02470, mce related protein, score 9.5e-23 291112010983 1 probable transmembrane helix predicted for PAT1535 by TMHMM2.0 at aa 19-41 291112010984 paraquat-inducible membrane protein A; Provisional; Region: PRK15103 291112010985 Paraquat-inducible protein A; Region: PqiA; pfam04403 291112010986 Paraquat-inducible protein A; Region: PqiA; pfam04403 291112010987 HMMPfam hit to PF04403, Paraquat-inducible protein A, score 2.8e-82 291112010988 8 probable transmembrane helices predicted for PAT1534 by TMHMM2.0 at aa 53-75, 99-121, 142-164, 168-185, 251-273, 288-310, 350-369 and 374-396 291112010989 HMMPfam hit to PF04403, Paraquat-inducible protein A, score 1.7e-61 291112010990 HMMPfam hit to PF04403, Paraquat-inducible protein A, score 2.1e-60 291112010991 3 probable transmembrane helices predicted for PAT1850 by TMHMM2.0 at aa 53-75, 99-121 and 150-172 291112010992 ABC transporter ATPase component; Reviewed; Region: PRK11147 291112010993 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112010994 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112010995 Walker A/P-loop; other site 291112010996 Walker A/P-loop; other site 291112010997 ATP binding site [chemical binding]; other site 291112010998 ATP binding site [chemical binding]; other site 291112010999 Q-loop/lid; other site 291112011000 Q-loop/lid; other site 291112011001 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112011002 ABC transporter signature motif; other site 291112011003 Walker B; other site 291112011004 D-loop; other site 291112011005 ABC transporter; Region: ABC_tran_2; pfam12848 291112011006 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112011007 HMMSmart hit to SM00382, no description, score 2.4e-11 291112011008 HMMPfam hit to PF00005, ABC transporter, score 8.8e-47 291112011009 HMMSmart hit to SM00382, no description, score 3.9e-14 291112011010 HMMPfam hit to PF00005, ABC transporter, score 3.2e-48 291112011011 23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783 291112011012 THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715 291112011013 Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170 291112011014 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112011015 S-adenosylmethionine binding site [chemical binding]; other site 291112011016 HMMPfam hit to PF01170, Putative RNA methylase family UPF0020, score 1.7e-87 291112011017 HMMPfam hit to PF02926, THUMP domain, score 2.8e-14 291112011018 Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217 291112011019 MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476 291112011020 MOSC domain; Region: MOSC; pfam03473 291112011021 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 291112011022 catalytic loop [active] 291112011023 iron binding site [ion binding]; other site 291112011024 HMMPfam hit to PF03476, MOSC N-terminal beta barrel domain, score 6.7e-32 291112011025 HMMPfam hit to PF03473, MOSC domain, score 1.4e-44 291112011026 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 6.2e-16 291112011027 Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819 291112011028 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 291112011029 active site 291112011030 TDP-binding site; other site 291112011031 acceptor substrate-binding pocket; other site 291112011032 Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819 291112011033 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 291112011034 active site 291112011035 TDP-binding site; other site 291112011036 acceptor substrate-binding pocket; other site 291112011037 HMMPfam hit to PF00201, UDP-glucoronosyl and UDP-glucosyl tra, score 0.0044 291112011038 HMMPfam hit to PF03033, Glycosyltransferase family 28 N-termi, score 0.0038 291112011039 HMMPfam hit to PF04101, Glycosyltransferase family 28 C-termi, score 0.0024 291112011040 Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819 291112011041 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 291112011042 active site 291112011043 TDP-binding site; other site 291112011044 acceptor substrate-binding pocket; other site 291112011045 HMMPfam hit to PF06722, Protein of unknown function (DUF1205), score 0.0043 291112011046 HMMPfam hit to PF04101, Glycosyltransferase family 28 C-termi, score 0.0024 291112011047 Protein of unknown function (DUF1379); Region: DUF1379; pfam07126 291112011048 HMMPfam hit to PF07126, Protein of unknown function (DUF1379), score 5.2e-71 291112011049 dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286 291112011050 Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738 291112011051 quinone interaction residues [chemical binding]; other site 291112011052 active site 291112011053 catalytic residues [active] 291112011054 FMN binding site [chemical binding]; other site 291112011055 substrate binding site [chemical binding]; other site 291112011056 HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 8.9e-101 291112011057 aminopeptidase N; Provisional; Region: pepN; PRK14015 291112011058 Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600 291112011059 active site 291112011060 Zn binding site [ion binding]; other site 291112011061 HMMPfam hit to PF01433, Peptidase family M1, score 2e-64 291112011062 nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514 291112011063 Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401 291112011064 active site 291112011065 HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase (NAPRTa, score 2.3e-116 291112011066 HMMPfam hit to PF04095, Nicotinate phosphoribosyltransferase (NAPRTa, score 2.7e-72 291112011067 asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932 291112011068 EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318 291112011069 putative dimer interface [polypeptide binding]; other site 291112011070 putative anticodon binding site; other site 291112011071 Asx tRNA synthetase (AspRS/AsnRS) class II core domain. Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776 291112011072 homodimer interface [polypeptide binding]; other site 291112011073 motif 1; other site 291112011074 motif 2; other site 291112011075 active site 291112011076 motif 3; other site 291112011077 HMMPfam hit to PF01336, OB-fold nucleic acid binding domain, score 2.4e-18 291112011078 HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 7.3e-81 291112011079 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 291112011080 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 291112011081 trimer interface [polypeptide binding]; other site 291112011082 eyelet of channel; other site 291112011083 HMMPfam hit to PF00267, Gram-negative porin, score 1.8e-171 291112011084 Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203 291112011085 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 291112011086 trimer interface [polypeptide binding]; other site 291112011087 eyelet of channel; other site 291112011088 HMMPfam hit to PF00267, Gram-negative porin, score 2.4e-186 291112011089 aromatic amino acid aminotransferase; Provisional; Region: PRK09257 291112011090 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112011091 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112011092 homodimer interface [polypeptide binding]; other site 291112011093 catalytic residue [active] 291112011094 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.2e-135 291112011095 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 291112011096 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 2.6e-37 291112011097 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108 291112011098 Peptidase M15; Region: Peptidase_M15_3; cl01194 291112011099 HMMPfam hit to PF05951, Bacterial protein of unknown function, score 1.2e-98 291112011100 HMMPfam hit to PF08291, Peptidase M15, score 2.2e-05 291112011101 murein L,D-transpeptidase; Provisional; Region: PRK10594 291112011102 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 291112011103 L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734 291112011104 L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734 291112011105 HMMPfam hit to PF01471, Putative peptidoglycan binding domain, score 1.9e-10 291112011106 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 291112011107 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112011108 AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246 291112011109 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 1.5e-16 291112011110 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654 291112011111 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 291112011112 HMMPfam hit to PF01494, FAD binding domain, score 9.4e-07 291112011113 Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; cl14901 291112011114 Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: VapC; COG1487 291112011115 putative active site [active] 291112011116 Uncharacterized protein conserved in bacteria (DUF2191); Region: DUF2191; pfam09957 291112011117 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 291112011118 Transposase; Region: DEDD_Tnp_IS110; pfam01548 291112011119 1 probable transmembrane helix predicted for PAT1510 by TMHMM2.0 at aa 38-60 291112011120 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 291112011121 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 291112011122 3 probable transmembrane helices predicted for PAT1509 by TMHMM2.0 at aa 125-147, 181-203 and 330-352 291112011123 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 1.9e-15 291112011124 HMMPfam hit to PF00482, Bacterial type II secretion system protein F, score 1.5e-10 291112011125 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 291112011126 Walker A motif; other site 291112011127 ATP binding site [chemical binding]; other site 291112011128 Walker B motif; other site 291112011129 HMMPfam hit to PF00437, Type II/IV secretion system protein, score 4.1e-35 291112011130 HMMSmart hit to SM00382, no description, score 0.0057 291112011131 type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021 291112011132 Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864 291112011133 type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520 291112011134 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 291112011135 HMMPfam hit to PF00263, Bacterial type II and III secretion syst, score 2.3e-26 291112011136 HMMPfam hit to PF07655, Secretin N-terminal domain, score 7.2e-33 291112011137 Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671 291112011138 1 probable transmembrane helix predicted for PAT1504 by TMHMM2.0 at aa 13-35 291112011139 1 probable transmembrane helix predicted for PAT1503 by TMHMM2.0 at aa 4-26 291112011140 Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917 291112011141 1 probable transmembrane helix predicted for PAT1851 by TMHMM2.0 at aa 20-42 291112011142 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989 291112011143 Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750 291112011144 5 probable transmembrane helices predicted for PAT1501 by TMHMM2.0 at aa 10-32, 95-117, 162-184, 204-226 and 241-263 291112011145 HMMPfam hit to PF01478, Type IV leader peptidase family, score 2.3e-22 291112011146 HMMPfam hit to PF06750, Bacterial Peptidase A24 N-terminal doma, score 8.3e-39 291112011147 PilS N terminal; Region: PilS; pfam08805 291112011148 1 probable transmembrane helix predicted for PAT1500 by TMHMM2.0 at aa 20-42 291112011149 ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496 291112011150 HMMPfam hit to PF06182, Protein of unknown function (DUF990), score 9.1e-43 291112011151 6 probable transmembrane helices predicted for PAT1499 by TMHMM2.0 at aa 27-49, 62-81, 117-139, 146-168, 188-210 and 223-245 291112011152 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4587 291112011153 ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496 291112011154 HMMPfam hit to PF06182, Protein of unknown function (DUF990), score 8.3e-14 291112011155 6 probable transmembrane helices predicted for PAT1498 by TMHMM2.0 at aa 30-49, 64-86, 121-143, 158-180, 193-215 and 240-262 291112011156 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4586 291112011157 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112011158 Walker A/P-loop; other site 291112011159 ATP binding site [chemical binding]; other site 291112011160 Q-loop/lid; other site 291112011161 ABC transporter signature motif; other site 291112011162 Walker B; other site 291112011163 D-loop; other site 291112011164 H-loop/switch region; other site 291112011165 HMMSmart hit to SM00382, no description, score 0.00015 291112011166 HMMPfam hit to PF00005, ABC transporter, score 2.6e-33 291112011167 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; cl17313 291112011168 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112011169 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112011170 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112011171 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841 291112011172 Phage protein D [General function prediction only]; Region: COG3500 291112011173 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 291112011174 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112011175 Gene 25-like lysozyme; Region: GPW_gp25; pfam04965 291112011176 HMMPfam hit to PF04965, GPW / gp25 family, score 5.3e-28 291112011177 Phage Tail Collar Domain; Region: Collar; pfam07484 291112011178 HMMPfam hit to PF00608, Adenoviral fibre protein (repeat/shaft re, score 0.027 291112011179 HMMPfam hit to PF00608, Adenoviral fibre protein (repeat/shaft re, score 0.072 291112011180 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 2.2e-13 291112011181 ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464 291112011182 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112011183 Walker A motif; other site 291112011184 ATP binding site [chemical binding]; other site 291112011185 Walker B motif; other site 291112011186 HMMSmart hit to SM00382, no description, score 1.7e-13 291112011187 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 8.1e-35 291112011188 Protein of unknown function (DUF4255); Region: DUF4255; pfam14065 291112011189 type III secretion protein GogB; Provisional; Region: PRK15386 291112011190 type III secretion protein GogB; Provisional; Region: PRK15386 291112011191 Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; Region: HX; cl02471 291112011192 Metal binding sites [ion binding]; metal-binding site 291112011193 Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472 291112011194 HMMPfam hit to PF00045, Hemopexin, score 1.6e-08; HMMSmart hit to SM00120, no description, score 0.0001 291112011195 HMMSmart hit to SM00120, no description, score 20 291112011196 HMMPfam hit to PF00045, Hemopexin, score 0.0017; HMMSmart hit to SM00120, no description, score 0.061 291112011197 HMMPfam hit to PF07472, Fucose-binding lectin II (PA-IIL), score 2.3e-61 291112011198 putative transposase; Provisional; Region: PRK09857 291112011199 Putative transposase, YhgA-like; Region: Transposase_31; pfam04754 291112011200 HMMPfam hit to PF04754, Putative transposase, YhgA-like, score 3.9e-191 291112011201 Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153 291112011202 HMMPfam hit to PF02604, Phd_YefM, score 2.2e-21 291112011203 cell division protein MukB; Provisional; Region: mukB; PRK04863 291112011204 MukB N-terminal; Region: MukB; pfam04310 291112011205 Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558 291112011206 HMMPfam hit to PF04310, MukB N-terminal, score 4.7e-179 291112011207 condesin subunit E; Provisional; Region: PRK05256 291112011208 HMMPfam hit to PF04288, MukE-like family, score 2.9e-146 291112011209 condesin subunit F; Provisional; Region: PRK05260 291112011210 HMMPfam hit to PF03882, KicB killing factor, score 0 291112011211 Methyltransferase domain; Region: Methyltransf_31; pfam13847 291112011212 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112011213 S-adenosylmethionine binding site [chemical binding]; other site 291112011214 HMMPfam hit to PF08241, Methyltransferase domain, score 4.7e-18 291112011215 HMMPfam hit to PF08242, Methyltransferase domain, score 4.8e-13 291112011216 Uncharacterized conserved protein [Function unknown]; Region: COG1434 291112011217 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 291112011218 putative active site [active] 291112011219 1 probable transmembrane helix predicted for PAT1471 by TMHMM2.0 at aa 10-32 291112011220 HMMPfam hit to PF02698, DUF218 domain, score 4e-46 291112011221 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450 291112011222 CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517 291112011223 Ligand binding site; other site 291112011224 oligomer interface; other site 291112011225 HMMPfam hit to PF02348, Cytidylyltransferase, score 7.7e-84 291112011226 Trm112p-like protein; Region: Trm112p; cl01066 291112011227 HMMPfam hit to PF03966, Trm112p-like protein, score 1e-19 291112011228 Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663 291112011229 tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652 291112011230 HMMPfam hit to PF02606, Tetraacyldisaccharide-1-P 4'-kinase, score 4.1e-132 291112011231 1 probable transmembrane helix predicted for PAT1468 by TMHMM2.0 at aa 7-29 291112011232 lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176 291112011233 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112011234 ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251 291112011235 Walker A/P-loop; other site 291112011236 ATP binding site [chemical binding]; other site 291112011237 Q-loop/lid; other site 291112011238 ABC transporter signature motif; other site 291112011239 Walker B; other site 291112011240 D-loop; other site 291112011241 H-loop/switch region; other site 291112011242 HMMPfam hit to PF00005, ABC transporter, score 9.1e-64 291112011243 HMMSmart hit to SM00382, no description, score 6.5e-18 291112011244 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 4.7e-65 291112011245 5 probable transmembrane helices predicted for PAT1467 by TMHMM2.0 at aa 21-43, 69-91, 143-162, 166-185 and 246-268 291112011246 ComEC family competence protein; Provisional; Region: PRK11539 291112011247 Domain of unknown function (DUF4131); Region: DUF4131; pfam13567 291112011248 Competence protein; Region: Competence; pfam03772 291112011249 Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753 291112011250 HMMPfam hit to PF00753, Metallo-beta-lactamase superfamily, score 3.4e-17 291112011251 9 probable transmembrane helices predicted for PAT1466 by TMHMM2.0 at aa 30-52, 62-84, 258-280, 300-322, 334-353, 363-380, 392-414, 429-451 and 484-506 291112011252 HMMPfam hit to PF03772, Competence protein, score 2.3e-46 291112011253 LysE type translocator; Region: LysE; cl00565 291112011254 6 probable transmembrane helices predicted for PAT1464 by TMHMM2.0 at aa 4-26, 39-61, 71-93, 113-132, 147-169 and 182-204 291112011255 HMMPfam hit to PF01810, LysE type translocator, score 2.4e-24 291112011256 Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320 291112011257 HMMPfam hit to PF01320, Colicin immunity protein / pyocin immu, score 1.1e-06 291112011258 S-type Pyocin; Region: Pyocin_S; pfam06958 291112011259 DNase/tRNase domain of colicin-like bacteriocin; Region: Colicin-DNase; pfam12639 291112011260 HMMPfam hit to PF06958, S-type Pyocin, score 4.3e-07 291112011261 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 291112011262 IHF dimer interface [polypeptide binding]; other site 291112011263 IHF - DNA interface [nucleotide binding]; other site 291112011264 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 1.2e-45; HMMSmart hit to SM00411, no description, score 2.4e-40 291112011265 HMMSmart hit to SM00411, no description, score 4.8e-07 291112011266 30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299 291112011267 S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687 291112011268 RNA binding site [nucleotide binding]; other site 291112011269 S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465 291112011270 RNA binding site [nucleotide binding]; other site 291112011271 S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688 291112011272 RNA binding site [nucleotide binding]; other site 291112011273 S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689 291112011274 RNA binding site [nucleotide binding]; other site 291112011275 S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927 291112011276 RNA binding site [nucleotide binding]; other site 291112011277 S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691 291112011278 RNA binding site [nucleotide binding]; other site 291112011279 HMMPfam hit to PF00575, S1 RNA binding domain, score 1.4e-20 291112011280 HMMSmart hit to SM00316, no description, score 6.4e-21 291112011281 HMMPfam hit to PF00575, S1 RNA binding domain, score 9.1e-26 291112011282 HMMSmart hit to SM00316, no description, score 5.3e-21 291112011283 HMMPfam hit to PF00575, S1 RNA binding domain, score 4.1e-30 291112011284 HMMSmart hit to SM00316, no description, score 2.2e-27 291112011285 HMMPfam hit to PF00575, S1 RNA binding domain, score 7e-32 291112011286 HMMSmart hit to SM00316, no description, score 2.8e-28 291112011287 HMMPfam hit to PF00575, S1 RNA binding domain, score 1e-17 291112011288 HMMSmart hit to SM00316, no description, score 1.8e-08 291112011289 HMMPfam hit to PF00575, S1 RNA binding domain, score 6.3e-13 291112011290 HMMSmart hit to SM00316, no description, score 0.00016 291112011291 cytidylate kinase; Provisional; Region: cmk; PRK00023 291112011292 Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020 291112011293 CMP-binding site; other site 291112011294 The sites determining sugar specificity; other site 291112011295 HMMPfam hit to PF02224, Cytidylate kinase, score 9.1e-82 291112011296 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427 291112011297 EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556 291112011298 hinge; other site 291112011299 active site 291112011300 HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 6.3e-217 291112011301 Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as...; Region: PSAT_like; cd00611 291112011302 homodimer interface [polypeptide binding]; other site 291112011303 substrate-cofactor binding pocket; other site 291112011304 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112011305 catalytic residue [active] 291112011306 HMMPfam hit to PF00266, Aminotransferase class-V, score 8.4e-59 291112011307 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.2e-05 291112011308 Protein of unknown function (DUF1778); Region: DUF1778; pfam08681 291112011309 L-asparaginase II; Provisional; Region: ansB; PRK11096 291112011310 homodimer interface [polypeptide binding]; other site 291112011311 active site 291112011312 HMMPfam hit to PF00710, Asparaginase, score 1.5e-148 291112011313 1 probable transmembrane helix predicted for PAT1454 by TMHMM2.0 at aa 7-29 291112011314 uncharacterized domain; Region: TIGR00702 291112011315 YcaO-like family; Region: YcaO; pfam02624 291112011316 HMMPfam hit to PF02624, YcaO-like family, score 1.3e-151 291112011317 formate transporter; Provisional; Region: PRK10805 291112011318 HMMPfam hit to PF01226, Formate/nitrite transporter, score 2.7e-153 291112011319 6 probable transmembrane helices predicted for PAT1452 by TMHMM2.0 at aa 35-57, 77-99, 119-141, 161-183, 195-217 and 256-278 291112011320 formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255 291112011321 Pyruvate formate lyase 1; Region: PFL1; cd01678 291112011322 coenzyme A binding site [chemical binding]; other site 291112011323 active site 291112011324 catalytic residues [active] 291112011325 glycine loop; other site 291112011326 HMMPfam hit to PF02901, Pyruvate formate lyase, score 0 291112011327 HMMPfam hit to PF01228, Glycine radical, score 6.1e-60 291112011328 pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145 291112011329 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112011330 FeS/SAM binding site; other site 291112011331 HMMPfam hit to PF04055, Radical SAM superfamily, score 7.8e-28 291112011332 5 probable transmembrane helices predicted for PAT1449 by TMHMM2.0 at aa 65-82, 86-108, 132-154, 189-211 and 232-254 291112011333 5 probable transmembrane helices predicted for PAT1448 by TMHMM2.0 at aa 51-68, 70-92, 126-148, 168-190 and 220-242 291112011334 seryl-tRNA synthetase; Provisional; Region: PRK05431 291112011335 Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403 291112011336 Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770 291112011337 dimer interface [polypeptide binding]; other site 291112011338 active site 291112011339 motif 1; other site 291112011340 motif 2; other site 291112011341 motif 3; other site 291112011342 HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 3.2e-71 291112011343 HMMPfam hit to PF02403, Seryl-tRNA synthetase N-terminal domain, score 5.2e-42 291112011344 recombination factor protein RarA; Reviewed; Region: PRK13342 291112011345 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112011346 Walker A motif; other site 291112011347 ATP binding site [chemical binding]; other site 291112011348 Walker B motif; other site 291112011349 arginine finger; other site 291112011350 MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002 291112011351 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 3.7e-19 291112011352 HMMSmart hit to SM00382, no description, score 1.8e-16 291112011353 Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548 291112011354 lipoprotein chaperone; Reviewed; Region: lolA; PRK00031 291112011355 HMMPfam hit to PF03548, Outer membrane lipoprotein carrier protein L, score 1.7e-71 291112011356 Domain of unknown function (DUF4117); Region: DUF4117; pfam13491 291112011357 Protein of unknown function (DUF998); Region: DUF998; pfam06197 291112011358 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 291112011359 Ftsk gamma domain; Region: Ftsk_gamma; pfam09397 291112011360 HMMPfam hit to PF01580, FtsK/SpoIIIE family, score 9.9e-103 291112011361 5 probable transmembrane helices predicted for PAT1444 by TMHMM2.0 at aa 22-44, 77-99, 112-134, 139-158 and 165-187 291112011362 leucine-responsive transcriptional regulator; Provisional; Region: PRK11169 291112011363 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 291112011364 putative DNA binding site [nucleotide binding]; other site 291112011365 putative Zn2+ binding site [ion binding]; other site 291112011366 AsnC family; Region: AsnC_trans_reg; pfam01037 291112011367 HMMPfam hit to PF01037, AsnC family, score 5.1e-31 291112011368 HMMSmart hit to SM00344, no description, score 1.3e-55 291112011369 thioredoxin reductase; Provisional; Region: PRK10262 291112011370 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 291112011371 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 291112011372 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 4.2e-54 291112011373 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 3.1e-22 291112011374 cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174 291112011375 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112011376 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112011377 Walker A/P-loop; other site 291112011378 ATP binding site [chemical binding]; other site 291112011379 Q-loop/lid; other site 291112011380 ABC transporter signature motif; other site 291112011381 Walker B; other site 291112011382 D-loop; other site 291112011383 H-loop/switch region; other site 291112011384 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 3.8e-30 291112011385 6 probable transmembrane helices predicted for PAT1441 by TMHMM2.0 at aa 30-52, 67-89, 144-161, 165-187, 246-268 and 278-300 291112011386 HMMSmart hit to SM00382, no description, score 2.3e-13 291112011387 HMMPfam hit to PF00005, ABC transporter, score 9.3e-63 291112011388 cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160 291112011389 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112011390 ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247 291112011391 Walker A/P-loop; other site 291112011392 ATP binding site [chemical binding]; other site 291112011393 Q-loop/lid; other site 291112011394 ABC transporter signature motif; other site 291112011395 Walker B; other site 291112011396 D-loop; other site 291112011397 H-loop/switch region; other site 291112011398 6 probable transmembrane helices predicted for PAT1440 by TMHMM2.0 at aa 13-35, 39-61, 133-155, 160-182, 242-264 and 279-301 291112011399 HMMSmart hit to SM00382, no description, score 7.9e-09 291112011400 HMMPfam hit to PF00005, ABC transporter, score 5.9e-56 291112011401 leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301 291112011402 HMMPfam hit to PF03588, Leucyl/phenylalanyl-tRNA protein transf, score 1.8e-89 291112011403 S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451 291112011404 rRNA binding site [nucleotide binding]; other site 291112011405 predicted 30S ribosome binding site; other site 291112011406 HMMPfam hit to PF00575, S1 RNA binding domain, score 1.6e-10 291112011407 HMMSmart hit to SM00316, no description, score 4.3e-07 291112011408 HMMPfam hit to PF01176, Translation initiation factor 1A / IF-1, score 1.5e-36 291112011409 ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034 291112011410 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112011411 Walker A motif; other site 291112011412 ATP binding site [chemical binding]; other site 291112011413 Walker B motif; other site 291112011414 arginine finger; other site 291112011415 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112011416 Walker A motif; other site 291112011417 ATP binding site [chemical binding]; other site 291112011418 Walker B motif; other site 291112011419 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 291112011420 HMMSmart hit to SM00382, no description, score 1.4e-08 291112011421 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 6e-07 291112011422 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 6.8e-91 291112011423 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.3e-17 291112011424 HMMSmart hit to SM00382, no description, score 5.3e-14 291112011425 HMMPfam hit to PF02861, Clp amino terminal domain, score 1e-16 291112011426 ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033 291112011427 HMMPfam hit to PF02617, ATP-dependent Clp protease adaptor protein C, score 7.2e-50 291112011428 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 291112011429 DNA-binding site [nucleotide binding]; DNA binding site 291112011430 RNA-binding motif; other site 291112011431 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 4.2e-38 291112011432 HMMSmart hit to SM00357, no description, score 7.6e-28 291112011433 macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535 291112011434 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 291112011435 Walker A/P-loop; other site 291112011436 ATP binding site [chemical binding]; other site 291112011437 Q-loop/lid; other site 291112011438 ABC transporter signature motif; other site 291112011439 Walker B; other site 291112011440 D-loop; other site 291112011441 H-loop/switch region; other site 291112011442 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 291112011443 FtsX-like permease family; Region: FtsX; pfam02687 291112011444 HMMPfam hit to PF02687, Predicted permease, score 1.1e-53 291112011445 4 probable transmembrane helices predicted for PAT1434 by TMHMM2.0 at aa 272-294, 526-548, 571-593 and 608-630 291112011446 HMMSmart hit to SM00382, no description, score 3.6e-15 291112011447 HMMPfam hit to PF00005, ABC transporter, score 1.1e-59 291112011448 macrolide transporter subunit MacA; Provisional; Region: PRK11578 291112011449 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112011450 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112011451 HMMPfam hit to PF00529, HlyD family secretion protein, score 0.00059 291112011452 1 probable transmembrane helix predicted for PAT1433 by TMHMM2.0 at aa 9-28 291112011453 Predicted membrane protein [Function unknown]; Region: COG2431 291112011454 8 probable transmembrane helices predicted for PAT1432 by TMHMM2.0 at aa 4-23, 35-54, 64-86, 115-137, 142-159, 172-194, 209-231 and 279-301 291112011455 HMMPfam hit to PF03956, Membrane protein of unknown function (DUF340, score 7.1e-76 291112011456 arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124 291112011457 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112011458 Walker A/P-loop; other site 291112011459 ATP binding site [chemical binding]; other site 291112011460 Q-loop/lid; other site 291112011461 ABC transporter signature motif; other site 291112011462 Walker B; other site 291112011463 D-loop; other site 291112011464 H-loop/switch region; other site 291112011465 HMMSmart hit to SM00382, no description, score 8.6e-14 291112011466 HMMPfam hit to PF00005, ABC transporter, score 1.2e-70 291112011467 putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007 291112011468 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112011469 substrate binding pocket [chemical binding]; other site 291112011470 membrane-bound complex binding site; other site 291112011471 hinge residues; other site 291112011472 HMMSmart hit to SM00062, no description, score 3.2e-84; HMMSmart hit to SM00079, no description, score 0.00014 291112011473 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 7.7e-94 291112011474 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 291112011475 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112011476 dimer interface [polypeptide binding]; other site 291112011477 conserved gate region; other site 291112011478 putative PBP binding loops; other site 291112011479 ABC-ATPase subunit interface; other site 291112011480 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.8e-14 291112011481 4 probable transmembrane helices predicted for PAT1429 by TMHMM2.0 at aa 10-32, 53-75, 99-118 and 201-223 291112011482 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 291112011483 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112011484 dimer interface [polypeptide binding]; other site 291112011485 conserved gate region; other site 291112011486 putative PBP binding loops; other site 291112011487 ABC-ATPase subunit interface; other site 291112011488 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.8e-13 291112011489 5 probable transmembrane helices predicted for PAT1428 by TMHMM2.0 at aa 15-37, 50-72, 92-114, 155-174 and 189-211 291112011490 23S rRNA methyluridine methyltransferase; Reviewed; Region: rumB; PRK03522 291112011491 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112011492 S-adenosylmethionine binding site [chemical binding]; other site 291112011493 HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 3.7e-07 291112011494 Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722 291112011495 hypothetical protein; Provisional; Region: PRK10591 291112011496 HMMPfam hit to PF07214, Protein of unknown function (DUF1418), score 8.8e-16 291112011497 2 probable transmembrane helices predicted for PAT1425 by TMHMM2.0 at aa 21-43 and 53-75 291112011498 Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066 291112011499 GSH binding site [chemical binding]; other site 291112011500 catalytic residues [active] 291112011501 HMMPfam hit to PF00462, Glutaredoxin, score 3.7e-14 291112011502 PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385 291112011503 active site 291112011504 4 probable transmembrane helices predicted for PAT1423 by TMHMM2.0 at aa 26-48, 63-85, 126-148 and 158-180 291112011505 HMMSmart hit to SM00014, no description, score 3.3e-11 291112011506 HMMPfam hit to PF01569, PAP2 superfamily, score 1.2e-15 291112011507 Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814 291112011508 serine transporter; Region: stp; TIGR00814 291112011509 HMMPfam hit to PF03845, Spore germination protein, score 0.00092 291112011510 HMMPfam hit to PF01490, Transmembrane amino acid transporter p, score 0.0046 291112011511 HMMPfam hit to PF03222, Tryptophan/tyrosine permease family, score 0.00029 291112011512 11 probable transmembrane helices predicted for PAT1422 by TMHMM2.0 at aa 48-65, 69-91, 125-144, 164-181, 188-210, 230-252, 273-295, 323-345, 374-396, 400-417 and 430-451 291112011513 D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793 291112011514 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 291112011515 Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943 291112011516 HMMPfam hit to PF07943, Penicillin-binding protein 5, C-termin, score 1.3e-36 291112011517 HMMPfam hit to PF00144, Beta-lactamase, score 0.0014 291112011518 HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 2.7e-140 291112011519 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 291112011520 GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047 291112011521 putative C-terminal domain interface [polypeptide binding]; other site 291112011522 putative GSH binding site (G-site) [chemical binding]; other site 291112011523 putative dimer interface [polypeptide binding]; other site 291112011524 C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180 291112011525 putative N-terminal domain interface [polypeptide binding]; other site 291112011526 putative dimer interface [polypeptide binding]; other site 291112011527 putative substrate binding pocket (H-site) [chemical binding]; other site 291112011528 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 4e-14 291112011529 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 2e-08 291112011530 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 291112011531 atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266 291112011532 putative NAD(P) binding site [chemical binding]; other site 291112011533 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fa, score 1e-05 291112011534 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 0.0025 291112011535 ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489 291112011536 ATP phosphoribosyltransferase; Region: hisG; TIGR00070 291112011537 ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455 291112011538 HMMPfam hit to PF01634, ATP phosphoribosyltransferase, score 4e-78 291112011539 HMMPfam hit to PF08029, HisG, C-terminal domain, score 9.9e-36 291112011540 Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141 291112011541 Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572 291112011542 NAD binding site [chemical binding]; other site 291112011543 dimerization interface [polypeptide binding]; other site 291112011544 product binding site; other site 291112011545 substrate binding site [chemical binding]; other site 291112011546 zinc binding site [ion binding]; other site 291112011547 catalytic residues [active] 291112011548 HMMPfam hit to PF00815, Histidinol dehydrogenase, score 1.5e-260 291112011549 histidinol-phosphate aminotransferase; Provisional; Region: PRK01688 291112011550 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112011551 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112011552 homodimer interface [polypeptide binding]; other site 291112011553 catalytic residue [active] 291112011554 HMMPfam hit to PF00155, Aminotransferase class I and II, score 7.4e-73 291112011555 imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446 291112011556 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112011557 active site 291112011558 motif I; other site 291112011559 motif II; other site 291112011560 Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914 291112011561 putative active site pocket [active] 291112011562 4-fold oligomerization interface [polypeptide binding]; other site 291112011563 metal binding residues [ion binding]; metal-binding site 291112011564 3-fold/trimer interface [polypeptide binding]; other site 291112011565 HMMPfam hit to PF00475, Imidazoleglycerol-phosphate dehydratase, score 2.1e-101 291112011566 imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170 291112011567 Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748 291112011568 putative active site [active] 291112011569 oxyanion strand; other site 291112011570 catalytic triad [active] 291112011571 HMMPfam hit to PF00117, Glutamine amidotransferase class-I, score 8.7e-46 291112011572 HisA. Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732 291112011573 Histidine biosynthesis protein; Region: His_biosynth; pfam00977 291112011574 catalytic residues [active] 291112011575 HMMPfam hit to PF00977, Histidine biosynthesis protein, score 1e-114 291112011576 The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731 291112011577 Histidine biosynthesis protein; Region: His_biosynth; pfam00977 291112011578 substrate binding site [chemical binding]; other site 291112011579 glutamase interaction surface [polypeptide binding]; other site 291112011580 HMMPfam hit to PF00977, Histidine biosynthesis protein, score 3.2e-117 291112011581 Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139 291112011582 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759 291112011583 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534 291112011584 metal binding site [ion binding]; metal-binding site 291112011585 HMMPfam hit to PF01502, Phosphoribosyl-AMP cyclohydrolase, score 9.8e-41 291112011586 HMMPfam hit to PF01503, Phosphoribosyl-ATP pyrophosphohydrolase, score 1e-40 291112011587 putative alcohol dehydrogenase; Provisional; Region: PRK09860 291112011588 Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176 291112011589 dimer interface [polypeptide binding]; other site 291112011590 active site 291112011591 metal binding site [ion binding]; metal-binding site 291112011592 HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 1.8e-202 291112011593 YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function. The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336 291112011594 putative deacylase active site [active] 291112011595 HMMPfam hit to PF04073, YbaK / prolyl-tRNA synthetases associated do, score 2.7e-38 291112011596 Protein of unkown function (DUF1881); Region: DUF1881; pfam08964 291112011597 Protein of unkown function (DUF1881); Region: DUF1881; pfam08964 291112011598 6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599 291112011599 6-phosphogluconate dehydrogenase; Validated; Region: PRK09287 291112011600 6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393 291112011601 HMMPfam hit to PF00393, 6-phosphogluconate dehydrogenase, C-ter, score 4.3e-223 291112011602 HMMPfam hit to PF03446, NAD binding domain of 6-phosphogluconat, score 4.4e-85 291112011603 Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861 291112011604 FOG: CBS domain [General function prediction only]; Region: COG0517 291112011605 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 291112011606 Transporter associated domain; Region: CorC_HlyC; smart01091 291112011607 HMMPfam hit to PF03741, Integral membrane protein TerC family, score 5e-30 291112011608 7 probable transmembrane helices predicted for PAT1402 by TMHMM2.0 at aa 13-35, 55-77, 82-99, 128-150, 154-171, 178-200 and 205-227 291112011609 HMMPfam hit to PF00571, CBS domain pair, score 6.6e-25 291112011610 HMMSmart hit to SM00116, no description, score 3.8 291112011611 HMMSmart hit to SM00116, no description, score 3.3 291112011612 HMMPfam hit to PF03471, Transporter associated domain, score 1.8e-16 291112011613 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112011614 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 291112011615 Coenzyme A binding pocket [chemical binding]; other site 291112011616 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 5.4e-15 291112011617 putative assembly protein; Provisional; Region: PRK10833 291112011618 AsmA-like C-terminal region; Region: AsmA_2; pfam13502 291112011619 HMMPfam hit to PF05170, AsmA family, score 5e-56 291112011620 1 probable transmembrane helix predicted for PAT1400 by TMHMM2.0 at aa 7-26 291112011621 Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557 291112011622 trimer interface [polypeptide binding]; other site 291112011623 active site 291112011624 HMMPfam hit to PF00692, dUTPase, score 7.4e-05 291112011625 Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572 291112011626 Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023 291112011627 ATP-binding site [chemical binding]; other site 291112011628 Sugar specificity; other site 291112011629 Pyrimidine base specificity; other site 291112011630 HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 1.9e-46 291112011631 antiporter inner membrane protein; Provisional; Region: PRK11670 291112011632 MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037 291112011633 methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133 291112011634 catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814 291112011635 active site 291112011636 HIGH motif; other site 291112011637 KMSKS motif; other site 291112011638 Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957 291112011639 tRNA binding surface [nucleotide binding]; other site 291112011640 anticodon binding site; other site 291112011641 The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human...; Region: tRNA_bindingDomain; cl00320 291112011642 putative tRNA-binding site [nucleotide binding]; other site 291112011643 HMMPfam hit to PF01588, Putative tRNA binding domain, score 5.4e-40 291112011644 hypothetical protein; Provisional; Region: PRK01821 291112011645 4 probable transmembrane helices predicted for PAT1395 by TMHMM2.0 at aa 21-43, 47-69, 81-98 and 108-130 291112011646 HMMPfam hit to PF03788, LrgA family, score 6.8e-49 291112011647 hypothetical protein; Provisional; Region: PRK10711 291112011648 6 probable transmembrane helices predicted for PAT1394 by TMHMM2.0 at aa 4-23, 30-52, 56-78, 91-113, 140-162 and 201-223 291112011649 HMMPfam hit to PF04172, LrgB-like family, score 3.7e-113 291112011650 cytidine deaminase; Provisional; Region: PRK09027 291112011651 Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283 291112011652 active site 291112011653 catalytic motif [active] 291112011654 Zn binding site [ion binding]; other site 291112011655 Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283 291112011656 active site 291112011657 catalytic motif [active] 291112011658 Zn binding site [ion binding]; other site 291112011659 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 2.4e-19 291112011660 HMMPfam hit to PF08211, Cytidine and deoxycytidylate deaminas, score 9.1e-78 291112011661 malate dehydrogenase; Provisional; Region: PRK13529 291112011662 Malic enzyme, N-terminal domain; Region: malic; pfam00390 291112011663 NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312 291112011664 NAD(P) binding site [chemical binding]; other site 291112011665 HMMPfam hit to PF00390, Malic enzyme, N-terminal domain, score 5.1e-125 291112011666 HMMPfam hit to PF03949, Malic enzyme, NAD binding domain, score 6.6e-142 291112011667 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 291112011668 putative active site [active] 291112011669 1 probable transmembrane helix predicted for PAT1391 by TMHMM2.0 at aa 17-39 291112011670 HMMPfam hit to PF02698, DUF218 domain, score 6.2e-39 291112011671 Predicted membrane protein [Function unknown]; Region: COG2311 291112011672 hypothetical protein; Provisional; Region: PRK10835 291112011673 HMMPfam hit to PF04235, Protein of unknown function (DUF418), score 2.3e-32 291112011674 10 probable transmembrane helices predicted for PAT1390 by TMHMM2.0 at aa 13-35, 50-72, 85-104, 109-126, 133-155, 201-223, 235-257, 277-299, 312-334 and 339-358 291112011675 HMMPfam hit to PF04171, Protein of unknown function (DUF405), score 2.8e-38 291112011676 GTP cyclohydrolase I; Provisional; Region: folE; PRK09347 291112011677 active site 291112011678 HMMPfam hit to PF01227, GTP cyclohydrolase I, score 1.1e-55 291112011679 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112011680 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112011681 putative substrate translocation pore; other site 291112011682 11 probable transmembrane helices predicted for PAT1388 by TMHMM2.0 at aa 15-37, 79-101, 106-128, 141-163, 173-192, 217-239, 249-271, 278-296, 300-322, 335-357 and 367-384 291112011683 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.1e-14 291112011684 HMMPfam hit to PF06779, Protein of unknown function (DUF1228), score 5.7e-35 291112011685 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565 291112011686 classical (c) SDRs; Region: SDR_c; cd05233 291112011687 NAD(P) binding site [chemical binding]; other site 291112011688 active site 291112011689 HMMPfam hit to PF00106, short chain dehydrogenase, score 3.7e-34 291112011690 molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680 291112011691 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 291112011692 dimer interface [polypeptide binding]; other site 291112011693 putative functional site; other site 291112011694 putative MPT binding site; other site 291112011695 HMMPfam hit to PF03453, MoeA N-terminal region (domain I and II, score 6.4e-74 291112011696 HMMPfam hit to PF00994, Probable molybdopterin binding domain, score 9.8e-48 291112011697 HMMPfam hit to PF03454, MoeA C-terminal region (domain IV), score 1e-20 291112011698 molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690 291112011699 ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757 291112011700 ATP binding site [chemical binding]; other site 291112011701 substrate interface [chemical binding]; other site 291112011702 HMMPfam hit to PF00899, ThiF family, score 2.3e-58 291112011703 HMMPfam hit to PF05237, MoeZ/MoeB domain, score 2.5e-31 291112011704 ABC transporter ATP-binding protein; Provisional; Region: PRK15064 291112011705 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112011706 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112011707 ABC transporter; Region: ABC_tran_2; pfam12848 291112011708 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 291112011709 HMMSmart hit to SM00382, no description, score 3.6e-11 291112011710 HMMPfam hit to PF00005, ABC transporter, score 8.1e-43 291112011711 HMMSmart hit to SM00382, no description, score 1.7e-09 291112011712 HMMPfam hit to PF00005, ABC transporter, score 4.7e-40 291112011713 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 291112011714 Coenzyme A binding pocket [chemical binding]; other site 291112011715 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.3e-06 291112011716 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979 291112011717 Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187 291112011718 dimer interface [polypeptide binding]; other site 291112011719 active site 291112011720 metal binding site [ion binding]; metal-binding site 291112011721 HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 5.2e-12 291112011722 Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130 291112011723 Prostaglandin dehydrogenases; Region: PGDH; cd05288 291112011724 NAD(P) binding site [chemical binding]; other site 291112011725 substrate binding site [chemical binding]; other site 291112011726 dimer interface [polypeptide binding]; other site 291112011727 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.6e-20 291112011728 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 291112011729 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112011730 Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611 291112011731 HMMPfam hit to PF03641, Possible lysine decarboxylase, score 6.9e-59 291112011732 threonine and homoserine efflux system; Provisional; Region: PRK10532 291112011733 EamA-like transporter family; Region: EamA; pfam00892 291112011734 9 probable transmembrane helices predicted for PAT1376 by TMHMM2.0 at aa 10-32, 39-61, 81-103, 124-141, 151-169, 176-198, 208-228, 241-260 and 264-286 291112011735 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 6e-19 291112011736 DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783 291112011737 DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043 291112011738 dimerization interface [polypeptide binding]; other site 291112011739 DPS ferroxidase diiron center [ion binding]; other site 291112011740 ion pore; other site 291112011741 HMMPfam hit to PF00210, Ferritin-like domain, score 3.9e-19 291112011742 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824 291112011743 PhnA protein; Region: PhnA; pfam03831 291112011744 HMMPfam hit to PF03831, PhnA protein, score 2.2e-27 291112011745 ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747 291112011746 DEAD/DEAH box helicase; Region: DEAD; pfam00270 291112011747 DEAD_2; Region: DEAD_2; pfam06733 291112011748 Helicase C-terminal domain; Region: Helicase_C_2; pfam13307 291112011749 HMMSmart hit to SM00491, no description, score 1e-25 291112011750 HMMSmart hit to SM00487, no description, score 1.1e-05 291112011751 HMMSmart hit to SM00488, no description, score 0.0018 291112011752 3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493 291112011753 Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448 291112011754 active site residue [active] 291112011755 Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449 291112011756 active site residue [active] 291112011757 HMMSmart hit to SM00450, no description, score 7.3e-23 291112011758 HMMPfam hit to PF00581, Rhodanese-like domain, score 3.2e-21 291112011759 HMMSmart hit to SM00450, no description, score 4.7e-20 291112011760 HMMPfam hit to PF00581, Rhodanese-like domain, score 7.9e-24 291112011761 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112011762 active site flap/lid [active] 291112011763 nucleophilic elbow; other site 291112011764 catalytic triad [active] 291112011765 HMMPfam hit to PF01764, Lipase (class 3), score 5.2e-06 291112011766 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112011767 active site flap/lid [active] 291112011768 nucleophilic elbow; other site 291112011769 catalytic triad [active] 291112011770 HMMPfam hit to PF01764, Lipase (class 3), score 1.6e-06 291112011771 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112011772 active site flap/lid [active] 291112011773 nucleophilic elbow; other site 291112011774 catalytic triad [active] 291112011775 HMMPfam hit to PF01764, Lipase (class 3), score 1.8e-06 291112011776 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112011777 active site flap/lid [active] 291112011778 nucleophilic elbow; other site 291112011779 catalytic triad [active] 291112011780 HMMPfam hit to PF01764, Lipase (class 3), score 6.7e-06 291112011781 tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550 291112011782 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 291112011783 FMN binding site [chemical binding]; other site 291112011784 active site 291112011785 catalytic residues [active] 291112011786 substrate binding site [chemical binding]; other site 291112011787 HMMPfam hit to PF01207, Dihydrouridine synthase (Dus), score 3.1e-123 291112011788 ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590 291112011789 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 291112011790 ATP binding site [chemical binding]; other site 291112011791 Mg++ binding site [ion binding]; other site 291112011792 motif III; other site 291112011793 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112011794 nucleotide binding region [chemical binding]; other site 291112011795 ATP-binding site [chemical binding]; other site 291112011796 HMMSmart hit to SM00490, no description, score 6.1e-30 291112011797 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 8.1e-31 291112011798 HMMSmart hit to SM00487, no description, score 3.1e-64 291112011799 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 5.7e-71 291112011800 putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552 291112011801 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112011802 Domain of unknown function (DUF1956); Region: DUF1956; pfam09209 291112011803 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.7e-10 291112011804 putative efflux pump membrane fusion protein; Provisional; Region: PRK03598 291112011805 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112011806 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112011807 1 probable transmembrane helix predicted for PAT1364 by TMHMM2.0 at aa 7-26 291112011808 HMMPfam hit to PF00529, HlyD family secretion protein, score 0.00028 291112011809 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 291112011810 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 291112011811 Walker A/P-loop; other site 291112011812 ATP binding site [chemical binding]; other site 291112011813 Q-loop/lid; other site 291112011814 ABC transporter signature motif; other site 291112011815 Walker B; other site 291112011816 D-loop; other site 291112011817 H-loop/switch region; other site 291112011818 ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555 291112011819 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 291112011820 Walker A/P-loop; other site 291112011821 ATP binding site [chemical binding]; other site 291112011822 Q-loop/lid; other site 291112011823 ABC transporter signature motif; other site 291112011824 Walker B; other site 291112011825 D-loop; other site 291112011826 H-loop/switch region; other site 291112011827 HMMSmart hit to SM00382, no description, score 2.5e-11 291112011828 HMMPfam hit to PF00005, ABC transporter, score 1.4e-46 291112011829 HMMSmart hit to SM00382, no description, score 1.6e-13 291112011830 HMMPfam hit to PF00005, ABC transporter, score 1.8e-44 291112011831 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 291112011832 ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679 291112011833 6 probable transmembrane helices predicted for PAT1362 by TMHMM2.0 at aa 35-57, 190-212, 239-261, 271-293, 298-320 and 356-378 291112011834 HMMPfam hit to PF01061, ABC-2 type transporter, score 4.1e-17 291112011835 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061 291112011836 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 291112011837 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 291112011838 HMMPfam hit to PF01061, ABC-2 type transporter, score 4.3e-35 291112011839 5 probable transmembrane helices predicted for PAT1361 by TMHMM2.0 at aa 175-197, 218-240, 255-277, 284-303 and 341-363 291112011840 drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710 291112011841 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112011842 putative substrate translocation pore; other site 291112011843 12 probable transmembrane helices predicted for PAT1360 by TMHMM2.0 at aa 5-27, 40-62, 74-96, 100-117, 129-148, 153-175, 203-225, 240-262, 271-293, 297-319, 332-354 and 359-376 291112011844 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.1e-41 291112011845 hypothetical protein; Provisional; Region: PRK07505 291112011846 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156 291112011847 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112011848 catalytic residue [active] 291112011849 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.8e-06 291112011850 Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670 291112011851 Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432 291112011852 HMMPfam hit to PF01027, Uncharacterised protein family UPF0005, score 1.3e-45 291112011853 7 probable transmembrane helices predicted for PAT1358 by TMHMM2.0 at aa 21-43, 53-75, 87-109, 114-133, 140-162, 167-186 and 211-233 291112011854 MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756 291112011855 MoaE homodimer interface [polypeptide binding]; other site 291112011856 MoaD interaction [polypeptide binding]; other site 291112011857 active site residues [active] 291112011858 HMMPfam hit to PF02391, MoaE protein, score 5.3e-56 291112011859 Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754 291112011860 MoaE interaction surface [polypeptide binding]; other site 291112011861 MoeB interaction surface [polypeptide binding]; other site 291112011862 thiocarboxylated glycine; other site 291112011863 HMMPfam hit to PF02597, ThiS family, score 9.6e-26 291112011864 MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420 291112011865 trimer interface [polypeptide binding]; other site 291112011866 dimer interface [polypeptide binding]; other site 291112011867 putative active site [active] 291112011868 HMMPfam hit to PF01967, MoaC family, score 7.9e-94 291112011869 molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164 291112011870 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112011871 FeS/SAM binding site; other site 291112011872 Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463 291112011873 HMMPfam hit to PF06463, Molybdenum Cofactor Synthesis C, score 3e-41 291112011874 HMMSmart hit to SM00729, no description, score 2.9e-05 291112011875 HMMPfam hit to PF04055, Radical SAM superfamily, score 2e-36 291112011876 conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826 291112011877 family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187 291112011878 phosphate binding site [ion binding]; other site 291112011879 putative substrate binding pocket [chemical binding]; other site 291112011880 dimer interface [polypeptide binding]; other site 291112011881 HMMPfam hit to PF01933, Uncharacterised protein family UPF0052, score 1.8e-118 291112011882 excinuclease ABC subunit B; Provisional; Region: PRK05298 291112011883 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112011884 ATP binding site [chemical binding]; other site 291112011885 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112011886 nucleotide binding region [chemical binding]; other site 291112011887 ATP-binding site [chemical binding]; other site 291112011888 Ultra-violet resistance protein B; Region: UvrB; pfam12344 291112011889 UvrB/uvrC motif; Region: UVR; pfam02151 291112011890 HMMPfam hit to PF02151, UvrB/uvrC motif, score 1.8e-11 291112011891 HMMSmart hit to SM00490, no description, score 8.9e-20 291112011892 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 6.2e-19 291112011893 HMMSmart hit to SM00487, no description, score 5.9e-27 291112011894 AAA domain; Region: AAA_26; pfam13500 291112011895 dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090 291112011896 HMMPfam hit to PF01656, CobQ/CobB/MinD/ParA nucleotide binding domai, score 1.7e-23 291112011897 biotin biosynthesis protein BioC; Region: BioC; TIGR02072 291112011898 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112011899 S-adenosylmethionine binding site [chemical binding]; other site 291112011900 HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 0.00029 291112011901 HMMPfam hit to PF08241, Methyltransferase domain, score 3e-30 291112011902 HMMPfam hit to PF08242, Methyltransferase domain, score 4.9e-14 291112011903 KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454 291112011904 Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155 291112011905 substrate-cofactor binding pocket; other site 291112011906 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112011907 catalytic residue [active] 291112011908 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.6e-77 291112011909 HMMPfam hit to PF00202, Aminotransferase class-III, score 0.0045 291112011910 biotin synthase; Provisional; Region: PRK15108 291112011911 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112011912 FeS/SAM binding site; other site 291112011913 Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876 291112011914 HMMPfam hit to PF06968, Biotin and Thiamin Synthesis associated d, score 1.2e-52 291112011915 HMMSmart hit to SM00729, no description, score 9.5e-42 291112011916 HMMPfam hit to PF04055, Radical SAM superfamily, score 3.3e-26 291112011917 adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986 291112011918 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 291112011919 inhibitor-cofactor binding pocket; inhibition site 291112011920 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112011921 catalytic residue [active] 291112011922 HMMPfam hit to PF00202, Aminotransferase class-III, score 3.3e-151 291112011923 6-phosphogluconolactonase; Provisional; Region: PRK11028 291112011924 pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530 291112011925 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112011926 active site 291112011927 motif I; other site 291112011928 motif II; other site 291112011929 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 291112011930 HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.0011 291112011931 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 2.7e-06 291112011932 HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 5.1e-77 291112011933 molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144 291112011934 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112011935 Walker A/P-loop; other site 291112011936 ATP binding site [chemical binding]; other site 291112011937 Q-loop/lid; other site 291112011938 ABC transporter signature motif; other site 291112011939 Walker B; other site 291112011940 D-loop; other site 291112011941 H-loop/switch region; other site 291112011942 molybdenum-pterin binding domain; Region: Mop; TIGR00638 291112011943 HMMPfam hit to PF03459, TOBE domain, score 3.3e-13 291112011944 HMMSmart hit to SM00382, no description, score 3e-11 291112011945 HMMPfam hit to PF00005, ABC transporter, score 8.2e-58 291112011946 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 291112011947 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112011948 dimer interface [polypeptide binding]; other site 291112011949 conserved gate region; other site 291112011950 putative PBP binding loops; other site 291112011951 ABC-ATPase subunit interface; other site 291112011952 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 7.9e-24 291112011953 5 probable transmembrane helices predicted for PAT1343 by TMHMM2.0 at aa 20-38, 50-72, 87-109, 137-159 and 197-219 291112011954 molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677 291112011955 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 291112011956 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 0.00023 291112011957 DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676 291112011958 N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005 291112011959 molybdenum-pterin binding domain; Region: Mop; TIGR00638 291112011960 TOBE domain; Region: TOBE; cl01440 291112011961 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 1.7e-12 291112011962 HMMPfam hit to PF03459, TOBE domain, score 5.2e-14 291112011963 HMMPfam hit to PF03459, TOBE domain, score 2.4e-07 291112011964 putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938 291112011965 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267 291112011966 Walker A/P-loop; other site 291112011967 ATP binding site [chemical binding]; other site 291112011968 Q-loop/lid; other site 291112011969 ABC transporter signature motif; other site 291112011970 Walker B; other site 291112011971 D-loop; other site 291112011972 H-loop/switch region; other site 291112011973 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112011974 Walker A/P-loop; other site 291112011975 ATP binding site [chemical binding]; other site 291112011976 Q-loop/lid; other site 291112011977 ABC transporter signature motif; other site 291112011978 Walker B; other site 291112011979 D-loop; other site 291112011980 H-loop/switch region; other site 291112011981 HMMSmart hit to SM00382, no description, score 2.5e-09 291112011982 HMMPfam hit to PF00005, ABC transporter, score 6.1e-24 291112011983 HMMSmart hit to SM00382, no description, score 3.6e-06 291112011984 HMMPfam hit to PF00005, ABC transporter, score 1.9e-44 291112011985 CAAX protease self-immunity; Region: Abi; pfam02517 291112011986 9 probable transmembrane helices predicted for PAT1339 by TMHMM2.0 at aa 13-32, 36-58, 70-87, 107-129, 141-163, 168-190, 202-221, 225-242 and 247-269 291112011987 HMMPfam hit to PF02517, CAAX amino terminal protease family, score 2e-16 291112011988 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 291112011989 catalytic core [active] 291112011990 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 291112011991 HMMPfam hit to PF00300, Phosphoglycerate mutase family, score 1.5e-46 291112011992 phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261 291112011993 DAHP synthetase I family; Region: DAHP_synth_1; pfam00793 291112011994 HMMPfam hit to PF00793, DAHP synthetase I family, score 2.3e-172 291112011995 nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397 291112011996 6 probable transmembrane helices predicted for PAT1336 by TMHMM2.0 at aa 20-39, 46-68, 72-89, 110-132, 158-177 and 184-206 291112011997 HMMPfam hit to PF04973, Nicotinamide mononucleotide transport, score 2.3e-71 291112011998 quinolinate synthetase; Provisional; Region: PRK09375 291112011999 HMMPfam hit to PF02445, Quinolinate synthetase A protein, score 6.8e-174 291112012000 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112012001 Phage Tail Collar Domain; Region: Collar; pfam07484 291112012002 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 8.9e-15 291112012003 similar to INSD:AE009952; similar to INSD:CP000305 291112012004 HMMPfam hit to PF03681, Uncharacterised protein family (UPF0150), score 3.7e-11 291112012005 tol-pal system protein YbgF; Provisional; Region: PRK10803 291112012006 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 291112012007 TPR motif; other site 291112012008 binding surface 291112012009 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0026 291112012010 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 1.5e-05 291112012011 1 probable transmembrane helix predicted for PAT1820 by TMHMM2.0 at aa 9-31 291112012012 1 probable transmembrane helix predicted for PAT1048 by TMHMM2.0 at aa 7-26 291112012013 peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802 291112012014 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 291112012015 ligand binding site [chemical binding]; other site 291112012016 HMMPfam hit to PF00691, OmpA family, score 3e-48 291112012017 translocation protein TolB; Provisional; Region: tolB; PRK03629 291112012018 TolB amino-terminal domain; Region: TolB_N; pfam04052 291112012019 WD40-like Beta Propeller Repeat; Region: PD40; pfam07676 291112012020 WD40-like Beta Propeller Repeat; Region: PD40; pfam07676 291112012021 WD40-like Beta Propeller Repeat; Region: PD40; pfam07676 291112012022 HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 0.19 291112012023 HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 7.4e-07 291112012024 HMMPfam hit to PF07676, WD40-like Beta Propeller Repeat, score 1.7e-06 291112012025 HMMPfam hit to PF04052, TolB amino-terminal domain, score 4.1e-78 291112012026 cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510 291112012027 TolA C-terminal; Region: TolA; pfam06519 291112012028 HMMPfam hit to PF06519, TolA protein, score 9.5e-142 291112012029 1 probable transmembrane helix predicted for PAT1045 by TMHMM2.0 at aa 13-35 291112012030 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 291112012031 colicin uptake protein TolR; Provisional; Region: PRK11024 291112012032 HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 4e-11 291112012033 1 probable transmembrane helix predicted for PAT1044 by TMHMM2.0 at aa 17-39 291112012034 colicin uptake protein TolQ; Provisional; Region: PRK10801 291112012035 HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 7.3e-61 291112012036 3 probable transmembrane helices predicted for PAT1043 by TMHMM2.0 at aa 15-37, 133-155 and 170-192 291112012037 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 291112012038 active site 291112012039 HMMPfam hit to PF03061, Thioesterase superfamily, score 5.4e-16 291112012040 Region 14-16 291112012041 1 probable transmembrane helix predicted for PAT1042 by TMHMM2.0 at aa 13-32 291112012042 hypothetical protein; Provisional; Region: PRK10588 291112012043 3 probable transmembrane helices predicted for PAT1041 by TMHMM2.0 at aa 13-35, 45-67 and 72-94 291112012044 Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039 291112012045 HMMPfam hit to PF08173, Membrane bound YbgT-like protein, score 1.4e-13 291112012046 1 probable transmembrane helix predicted for PAT1040 by TMHMM2.0 at aa 2-24 291112012047 cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219 291112012048 Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322 291112012049 HMMPfam hit to PF02322, Cytochrome oxidase subunit II, score 1.3e-208 291112012050 8 probable transmembrane helices predicted for PAT1039 by TMHMM2.0 at aa 7-24, 77-99, 122-144, 159-181, 202-224, 262-281, 293-315 and 335-357 291112012051 cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097 291112012052 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562 291112012053 HMMPfam hit to PF01654, Bacterial Cytochrome Ubiquinol Oxidase, score 0 291112012054 9 probable transmembrane helices predicted for PAT1038 by TMHMM2.0 at aa 20-42, 54-76, 96-118, 125-147, 184-206, 219-238, 387-409, 421-443 and 471-493 291112012055 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112012056 Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081 291112012057 protein-splicing catalytic site; other site 291112012058 thioester formation/cholesterol transfer; other site 291112012059 1 probable transmembrane helix predicted for PAT1036 by TMHMM2.0 at aa 32-49 291112012060 HMMSmart hit to SM00306, no description, score 7.8e-12 291112012061 Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081 291112012062 protein-splicing catalytic site; other site 291112012063 thioester formation/cholesterol transfer; other site 291112012064 HMMSmart hit to SM00306, no description, score 2.6e-10 291112012065 succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678 291112012066 CoA binding domain; Region: CoA_binding; smart00881 291112012067 CoA-ligase; Region: Ligase_CoA; pfam00549 291112012068 HMMPfam hit to PF00549, CoA-ligase, score 2.8e-66 291112012069 HMMPfam hit to PF02629, CoA binding domain, score 7.3e-52 291112012070 succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696 291112012071 ATP-grasp domain; Region: ATP-grasp_2; pfam08442 291112012072 CoA-ligase; Region: Ligase_CoA; pfam00549 291112012073 HMMPfam hit to PF00549, CoA-ligase, score 4.6e-80 291112012074 HMMPfam hit to PF08442, ATP-grasp domain, score 3e-129 291112012075 dihydrolipoamide succinyltransferase; Validated; Region: PRK05704 291112012076 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 291112012077 E3 interaction surface; other site 291112012078 lipoyl attachment site [posttranslational modification]; other site 291112012079 e3 binding domain; Region: E3_binding; pfam02817 291112012080 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 291112012081 HMMPfam hit to PF00198, 2-oxoacid dehydrogenases acyltransferas, score 3.5e-142 291112012082 HMMPfam hit to PF02817, e3 binding domain, score 1.9e-17 291112012083 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 6.3e-20 291112012084 2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404 291112012085 Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016 291112012086 TPP-binding site [chemical binding]; other site 291112012087 Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779 291112012088 dimer interface [polypeptide binding]; other site 291112012089 PYR/PP interface [polypeptide binding]; other site 291112012090 TPP binding site [chemical binding]; other site 291112012091 HMMPfam hit to PF02779, Transketolase, pyridine binding domain, score 6.5e-75 291112012092 HMMPfam hit to PF00676, Dehydrogenase E1 component, score 1.8e-29 291112012093 succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950 291112012094 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085 291112012095 succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958 291112012096 L-aspartate oxidase; Provisional; Region: PRK06175 291112012097 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 291112012098 HMMPfam hit to PF02910, Fumarate reductase/succinate dehydroge, score 9e-67 291112012099 HMMPfam hit to PF00890, FAD binding domain, score 2.3e-173 291112012100 Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494 291112012101 SdhC subunit interface [polypeptide binding]; other site 291112012102 proximal heme binding site [chemical binding]; other site 291112012103 cardiolipin binding site; other site 291112012104 Iron-sulfur protein interface; other site 291112012105 proximal quinone binding site [chemical binding]; other site 291112012106 3 probable transmembrane helices predicted for PAT1028 by TMHMM2.0 at aa 17-39, 59-81 and 91-113 291112012107 Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499 291112012108 Iron-sulfur protein interface; other site 291112012109 proximal quinone binding site [chemical binding]; other site 291112012110 SdhD (CybS) interface [polypeptide binding]; other site 291112012111 proximal heme binding site [chemical binding]; other site 291112012112 3 probable transmembrane helices predicted for PAT1027 by TMHMM2.0 at aa 27-49, 64-86 and 106-128 291112012113 HMMPfam hit to PF01127, Succinate dehydrogenase cytochrome b subunit, score 4.9e-39 291112012114 Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114 291112012115 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 291112012116 dimer interface [polypeptide binding]; other site 291112012117 active site 291112012118 citrylCoA binding site [chemical binding]; other site 291112012119 NADH binding [chemical binding]; other site 291112012120 cationic pore residues; other site 291112012121 oxalacetate/citrate binding site [chemical binding]; other site 291112012122 coenzyme A binding site [chemical binding]; other site 291112012123 catalytic triad [active] 291112012124 HMMPfam hit to PF00285, Citrate synthase, score 4e-235 291112012125 Uncharacterized conserved protein [Function unknown]; Region: COG0327 291112012126 metal-binding protein; Provisional; Region: PRK10799 291112012127 HMMPfam hit to PF01784, NIF3 (NGG1p interacting factor 3), score 5e-103 291112012128 Protein of unknown function (DUF2517); Region: DUF2517; pfam10725 291112012129 1 probable transmembrane helix predicted for PAT1024 by TMHMM2.0 at aa 12-31 291112012130 lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222 291112012131 HMMPfam hit to PF00036, EF hand, score 0.0048 291112012132 potassium-transporting ATPase subunit A; Provisional; Region: PRK05482 291112012133 12 probable transmembrane helices predicted for PAT1019 by TMHMM2.0 at aa 5-27, 67-89, 135-157, 178-200, 258-280, 287-306, 332-354, 359-381, 385-404, 421-443, 488-510 and 531-553 291112012134 HMMPfam hit to PF03814, Potassium-transporting ATPase A subunit, score 0 291112012135 potassium-transporting ATPase subunit B; Provisional; Region: PRK01122 291112012136 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 291112012137 7 probable transmembrane helices predicted for PAT1018 by TMHMM2.0 at aa 31-53, 63-85, 219-241, 256-278, 581-603, 618-640 and 660-682 291112012138 HMMPfam hit to PF00122, E1-E2 ATPase, score 1.2e-58 291112012139 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 1.9e-34 291112012140 potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315 291112012141 HMMPfam hit to PF02669, K+-transporting ATPase, c chain, score 7.1e-88 291112012142 1 probable transmembrane helix predicted for PAT1017 by TMHMM2.0 at aa 7-29 291112012143 sensor protein KdpD; Provisional; Region: PRK10490 291112012144 Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702 291112012145 USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987 291112012146 Ligand Binding Site [chemical binding]; other site 291112012147 Domain of unknown function (DUF4118); Region: DUF4118; pfam13493 291112012148 GAF domain; Region: GAF_3; pfam13492 291112012149 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112012150 dimer interface [polypeptide binding]; other site 291112012151 phosphorylation site [posttranslational modification] 291112012152 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112012153 ATP binding site [chemical binding]; other site 291112012154 Mg2+ binding site [ion binding]; other site 291112012155 G-X-G motif; other site 291112012156 HMMPfam hit to PF02702, Osmosensitive K+ channel His kinase sensor, score 1.9e-146 291112012157 HMMPfam hit to PF00582, Universal stress protein family, score 9.6e-08 291112012158 4 probable transmembrane helices predicted for PAT1016 by TMHMM2.0 at aa 403-425, 432-449, 453-475 and 482-504 291112012159 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.8e-17; HMMSmart hit to SM00388, no description, score 9.2e-16 291112012160 HMMSmart hit to SM00387, no description, score 1.5e-30 291112012161 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 3.4e-35 291112012162 DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529 291112012163 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112012164 active site 291112012165 phosphorylation site [posttranslational modification] 291112012166 intermolecular recognition site; other site 291112012167 dimerization interface [polypeptide binding]; other site 291112012168 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112012169 DNA binding site [nucleotide binding] 291112012170 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.2e-39 291112012171 HMMSmart hit to SM00448, no description, score 6.1e-36 291112012172 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2e-15 291112012173 MAC/Perforin domain; Region: MACPF; cl02616 291112012174 HMMPfam hit to PF01823, MAC/Perforin domain, score 0.0022 291112012175 putative hydrolase; Provisional; Region: PRK10976 291112012176 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915 291112012177 HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.00013 291112012178 HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 1.1e-61 291112012179 phosphoglucomutase; Validated; Region: PRK07564 291112012180 This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801 291112012181 active site 291112012182 substrate binding site [chemical binding]; other site 291112012183 metal binding site [ion binding]; metal-binding site 291112012184 HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 1.2e-10 291112012185 HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 3.4e-26 291112012186 HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 4.1e-21 291112012187 HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 1.9e-40 291112012188 replication initiation regulator SeqA; Provisional; Region: PRK11187 291112012189 HMMPfam hit to PF03925, SeqA protein, score 7.7e-106 291112012190 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112012191 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 291112012192 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287 291112012193 active site 291112012194 Int/Topo IB signature motif; other site 291112012195 CHC2 zinc finger; Region: zf-CHC2; cl17510 291112012196 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112012197 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112012198 active site 291112012199 metal binding site [ion binding]; metal-binding site 291112012200 interdomain interaction site; other site 291112012201 HMMPfam hit to PF01751, TOPRIM, score 1.7e-07 291112012202 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 5.5e-13 291112012203 HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 2.7e-27 291112012204 SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346 291112012205 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287 291112012206 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112012207 active site 291112012208 DNA binding site [nucleotide binding] 291112012209 Int/Topo IB signature motif; other site 291112012210 HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 1.5e-39 291112012211 CHC2 zinc finger; Region: zf-CHC2; cl17510 291112012212 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112012213 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112012214 active site 291112012215 metal binding site [ion binding]; metal-binding site 291112012216 interdomain interaction site; other site 291112012217 HMMPfam hit to PF01751, TOPRIM, score 1e-05 291112012218 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 1.6e-12 291112012219 HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 1.1e-26 291112012220 PAAR motif; Region: PAAR_motif; pfam05488 291112012221 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 291112012222 RHS Repeat; Region: RHS_repeat; pfam05593 291112012223 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 291112012224 RHS protein; Region: RHS; pfam03527 291112012225 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 291112012226 HMMPfam hit to PF05593, RHS Repeat, score 0.012 291112012227 HMMPfam hit to PF05593, RHS Repeat, score 2.1 291112012228 HMMPfam hit to PF05593, RHS Repeat, score 0.0029 291112012229 HMMPfam hit to PF05593, RHS Repeat, score 0.89 291112012230 HMMPfam hit to PF05593, RHS Repeat, score 0.0021 291112012231 HMMPfam hit to PF05593, RHS Repeat, score 0.00018 291112012232 HMMPfam hit to PF05593, RHS Repeat, score 0.0061 291112012233 HMMPfam hit to PF05593, RHS Repeat, score 0.0037 291112012234 HMMPfam hit to PF05593, RHS Repeat, score 0.91 291112012235 HMMPfam hit to PF05593, RHS Repeat, score 3.2 291112012236 HMMPfam hit to PF05593, RHS Repeat, score 1.2 291112012237 HMMPfam hit to PF05593, RHS Repeat, score 6.9 291112012238 HMMPfam hit to PF05593, RHS Repeat, score 0.21 291112012239 HMMPfam hit to PF05488, PAAR motif, score 0.00011 291112012240 HMMPfam hit to PF05488, PAAR motif, score 0.0065 291112012241 2 probable transmembrane helices predicted for PAT0992 by TMHMM2.0 at aa 15-37 and 42-64 291112012242 Domain of unknown function (DUF1795); Region: DUF1795; pfam08786 291112012243 acyl-CoA esterase; Provisional; Region: PRK10673 291112012244 PGAP1-like protein; Region: PGAP1; pfam07819 291112012245 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 1.6e-18 291112012246 HMMPfam hit to PF07819, PGAP1-like protein, score 3.7e-08 291112012247 C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663 291112012248 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 291112012249 8 probable transmembrane helices predicted for PAT0989 by TMHMM2.0 at aa 5-27, 47-64, 77-99, 141-163, 184-206, 219-241, 326-348 and 352-374 291112012250 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 5e-199 291112012251 Domain of unknown function (DUF1795); Region: DUF1795; cl02256 291112012252 PAAR motif; Region: PAAR_motif; pfam05488 291112012253 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 291112012254 RHS Repeat; Region: RHS_repeat; pfam05593 291112012255 RHS Repeat; Region: RHS_repeat; pfam05593 291112012256 RHS Repeat; Region: RHS_repeat; cl11982 291112012257 RHS Repeat; Region: RHS_repeat; pfam05593 291112012258 RHS Repeat; Region: RHS_repeat; pfam05593 291112012259 RHS Repeat; Region: RHS_repeat; pfam05593 291112012260 RHS Repeat; Region: RHS_repeat; pfam05593 291112012261 3 probable transmembrane helices predicted for PAT0987 by TMHMM2.0 at aa 68-90, 138-160 and 167-189 291112012262 HMMPfam hit to PF05488, PAAR motif, score 1.4e-09 291112012263 HMMPfam hit to PF05488, PAAR motif, score 5e-09 291112012264 HMMPfam hit to PF05593, RHS Repeat, score 0.38 291112012265 HMMPfam hit to PF05593, RHS Repeat, score 0.0035 291112012266 HMMPfam hit to PF05593, RHS Repeat, score 0.00076 291112012267 HMMPfam hit to PF05593, RHS Repeat, score 0.00048 291112012268 HMMPfam hit to PF05593, RHS Repeat, score 0.036 291112012269 HMMPfam hit to PF05593, RHS Repeat, score 0.0041 291112012270 HMMPfam hit to PF05593, RHS Repeat, score 3.3e-05 291112012271 HMMPfam hit to PF05593, RHS Repeat, score 5.2 291112012272 HMMPfam hit to PF05593, RHS Repeat, score 0.0058 291112012273 HMMPfam hit to PF05593, RHS Repeat, score 3.2e-05 291112012274 Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845 291112012275 choice-of-anchor C domain; Region: choice_anch_C; TIGR04362 291112012276 Peptidase C80 family; Region: Peptidase_C80; pfam11713 291112012277 RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931 291112012278 HMMPfam hit to PF07634, RtxA repeat, score 5.4 291112012279 HMMPfam hit to PF07634, RtxA repeat, score 1.8 291112012280 HMMPfam hit to PF07634, RtxA repeat, score 0.053 291112012281 HMMPfam hit to PF07634, RtxA repeat, score 2.5 291112012282 HMMPfam hit to PF07634, RtxA repeat, score 0.83 291112012283 HMMPfam hit to PF07634, RtxA repeat, score 1.2 291112012284 HMMPfam hit to PF07634, RtxA repeat, score 0.2 291112012285 HMMPfam hit to PF07634, RtxA repeat, score 0.00059 291112012286 HMMPfam hit to PF07634, RtxA repeat, score 7.6 291112012287 HMMPfam hit to PF07634, RtxA repeat, score 0.00017 291112012288 HMMPfam hit to PF07634, RtxA repeat, score 0.18 291112012289 HMMPfam hit to PF07634, RtxA repeat, score 0.025 291112012290 HMMPfam hit to PF07634, RtxA repeat, score 5.8 291112012291 HMMPfam hit to PF07634, RtxA repeat, score 9.8 291112012292 HMMPfam hit to PF07634, RtxA repeat, score 0.014 291112012293 HMMPfam hit to PF07634, RtxA repeat, score 2.1 291112012294 HMMPfam hit to PF07634, RtxA repeat, score 0.13 291112012295 HMMPfam hit to PF07634, RtxA repeat, score 5.7 291112012296 HMMPfam hit to PF07634, RtxA repeat, score 0.011 291112012297 HMMPfam hit to PF07634, RtxA repeat, score 0.0013 291112012298 HMMPfam hit to PF07634, RtxA repeat, score 0.0012 291112012299 HMMPfam hit to PF07634, RtxA repeat, score 0.21 291112012300 HMMPfam hit to PF07634, RtxA repeat, score 0.029 291112012301 HMMPfam hit to PF07634, RtxA repeat, score 0.011 291112012302 HMMPfam hit to PF07634, RtxA repeat, score 0.34 291112012303 HMMPfam hit to PF07634, RtxA repeat, score 0.069 291112012304 HMMPfam hit to PF07634, RtxA repeat, score 0.0015 291112012305 HMMPfam hit to PF07634, RtxA repeat, score 0.02 291112012306 HMMPfam hit to PF07634, RtxA repeat, score 0.0041 291112012307 HMMPfam hit to PF07634, RtxA repeat, score 0.0019 291112012308 HMMPfam hit to PF07634, RtxA repeat, score 0.039 291112012309 HMMPfam hit to PF07634, RtxA repeat, score 2.9 291112012310 HMMPfam hit to PF07634, RtxA repeat, score 1.2 291112012311 HMMPfam hit to PF07634, RtxA repeat, score 0.051 291112012312 HMMPfam hit to PF07634, RtxA repeat, score 0.32 291112012313 HMMPfam hit to PF07634, RtxA repeat, score 0.0016 291112012314 HMMPfam hit to PF07634, RtxA repeat, score 0.00074 291112012315 HMMPfam hit to PF07634, RtxA repeat, score 1 291112012316 HMMPfam hit to PF07634, RtxA repeat, score 0.02 291112012317 HMMPfam hit to PF07634, RtxA repeat, score 0.0027 291112012318 HMMPfam hit to PF07634, RtxA repeat, score 0.03 291112012319 HMMPfam hit to PF07634, RtxA repeat, score 0.052 291112012320 HMMPfam hit to PF07634, RtxA repeat, score 0.0014 291112012321 HMMPfam hit to PF07634, RtxA repeat, score 0.26 291112012322 HMMPfam hit to PF07634, RtxA repeat, score 1.5 291112012323 HMMPfam hit to PF07634, RtxA repeat, score 0.48 291112012324 N-terminal formyl transferase catalytic core domain of NRPS_like proteins, one of the proteins involved in the synthesis of Oxazolomycin; Region: FMT_core_NRPS_like; cd08649 291112012325 Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223 291112012326 putative active site [active] 291112012327 putative substrate binding site [chemical binding]; other site 291112012328 putative cosubstrate binding site; other site 291112012329 catalytic site [active] 291112012330 C-terminal subdomain of the Formyltransferase-like domain found in OzmH-like proteins; Region: FMT_C_OzmH_like; cd08700 291112012331 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112012332 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112012333 acyl-activating enzyme (AAE) consensus motif; other site 291112012334 AMP binding site [chemical binding]; other site 291112012335 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012336 Condensation domain; Region: Condensation; pfam00668 291112012337 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112012338 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112012339 acyl-activating enzyme (AAE) consensus motif; other site 291112012340 AMP binding site [chemical binding]; other site 291112012341 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012342 Condensation domain; Region: Condensation; pfam00668 291112012343 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112012344 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112012345 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112012346 acyl-activating enzyme (AAE) consensus motif; other site 291112012347 AMP binding site [chemical binding]; other site 291112012348 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012349 Condensation domain; Region: Condensation; pfam00668 291112012350 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112012351 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112012352 acyl-activating enzyme (AAE) consensus motif; other site 291112012353 AMP binding site [chemical binding]; other site 291112012354 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012355 Condensation domain; Region: Condensation; pfam00668 291112012356 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112012357 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112012358 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112012359 acyl-activating enzyme (AAE) consensus motif; other site 291112012360 AMP binding site [chemical binding]; other site 291112012361 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012362 Condensation domain; Region: Condensation; pfam00668 291112012363 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112012364 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112012365 acyl-activating enzyme (AAE) consensus motif; other site 291112012366 AMP binding site [chemical binding]; other site 291112012367 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012368 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 291112012369 HMMPfam hit to PF00975, Thioesterase domain, score 9.1e-14 291112012370 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 7.2e-09 291112012371 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.2e-151 291112012372 HMMPfam hit to PF00668, Condensation domain, score 9.6e-30 291112012373 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.1e-15 291112012374 HMMPfam hit to PF00501, AMP-binding enzyme, score 1e-156 291112012375 HMMPfam hit to PF00668, Condensation domain, score 1.5e-91 291112012376 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 7.8e-21 291112012377 HMMPfam hit to PF00501, AMP-binding enzyme, score 7.5e-157 291112012378 HMMPfam hit to PF00668, Condensation domain, score 6e-33 291112012379 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.5e-14 291112012380 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.2e-154 291112012381 HMMPfam hit to PF00668, Condensation domain, score 2.1e-80 291112012382 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.1e-16 291112012383 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.8e-153 291112012384 HMMPfam hit to PF00668, Condensation domain, score 3.8e-24 291112012385 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 4.8e-15 291112012386 HMMPfam hit to PF00501, AMP-binding enzyme, score 5.4e-159 291112012387 HMMPfam hit to PF00551, Formyl transferase, score 1.6e-06 291112012388 formamidase; Provisional; Region: amiF; PRK13287 291112012389 aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565 291112012390 multimer interface [polypeptide binding]; other site 291112012391 active site 291112012392 catalytic triad [active] 291112012393 dimer interface [polypeptide binding]; other site 291112012394 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 1.9e-22 291112012395 1 probable transmembrane helix predicted for PAT0980 by TMHMM2.0 at aa 33-55 291112012396 S-type Pyocin; Region: Pyocin_S; pfam06958 291112012397 Protein of unknown function, DUF596; Region: DUF596; cl10492 291112012398 HMMPfam hit to PF04591, Protein of unknown function, DUF596, score 7.7e-20 291112012399 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 291112012400 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112012401 Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210 291112012402 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112012403 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112012404 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112012405 Peptidase C80 family; Region: Peptidase_C80; pfam11713 291112012406 HMMPfam hit to PF07634, RtxA repeat, score 8.3 291112012407 HMMPfam hit to PF07634, RtxA repeat, score 5.7 291112012408 HMMPfam hit to PF07634, RtxA repeat, score 0.024 291112012409 HMMPfam hit to PF07634, RtxA repeat, score 0.055 291112012410 HMMPfam hit to PF07634, RtxA repeat, score 19 291112012411 HMMPfam hit to PF07634, RtxA repeat, score 0.62 291112012412 HMMPfam hit to PF07634, RtxA repeat, score 0.00021 291112012413 HMMPfam hit to PF07634, RtxA repeat, score 1.8 291112012414 HMMPfam hit to PF07634, RtxA repeat, score 0.027 291112012415 HMMPfam hit to PF07634, RtxA repeat, score 0.11 291112012416 HMMPfam hit to PF07634, RtxA repeat, score 0.0026 291112012417 HMMPfam hit to PF07634, RtxA repeat, score 5.8 291112012418 HMMPfam hit to PF07634, RtxA repeat, score 1.3 291112012419 HMMPfam hit to PF07634, RtxA repeat, score 0.027 291112012420 HMMPfam hit to PF07634, RtxA repeat, score 0.047 291112012421 HMMPfam hit to PF07634, RtxA repeat, score 0.11 291112012422 HMMPfam hit to PF07634, RtxA repeat, score 1.5 291112012423 HMMPfam hit to PF07634, RtxA repeat, score 1.5 291112012424 HMMPfam hit to PF07634, RtxA repeat, score 0.0042 291112012425 HMMPfam hit to PF07634, RtxA repeat, score 0.00075 291112012426 HMMPfam hit to PF07634, RtxA repeat, score 0.24 291112012427 HMMPfam hit to PF07634, RtxA repeat, score 0.026 291112012428 HMMPfam hit to PF07634, RtxA repeat, score 0.043 291112012429 HMMPfam hit to PF07634, RtxA repeat, score 0.034 291112012430 HMMPfam hit to PF07634, RtxA repeat, score 0.015 291112012431 HMMPfam hit to PF07634, RtxA repeat, score 0.002 291112012432 HMMPfam hit to PF07634, RtxA repeat, score 0.0098 291112012433 HMMPfam hit to PF07634, RtxA repeat, score 0.003 291112012434 HMMPfam hit to PF07634, RtxA repeat, score 0.0011 291112012435 HMMPfam hit to PF07634, RtxA repeat, score 0.00075 291112012436 HMMPfam hit to PF07634, RtxA repeat, score 16 291112012437 HMMPfam hit to PF07634, RtxA repeat, score 0.023 291112012438 HMMPfam hit to PF07634, RtxA repeat, score 8.1 291112012439 HMMPfam hit to PF07634, RtxA repeat, score 0.0018 291112012440 HMMPfam hit to PF07634, RtxA repeat, score 0.0017 291112012441 HMMPfam hit to PF07634, RtxA repeat, score 0.0014 291112012442 HMMPfam hit to PF07634, RtxA repeat, score 0.069 291112012443 HMMPfam hit to PF07634, RtxA repeat, score 0.014 291112012444 HMMPfam hit to PF07634, RtxA repeat, score 0.13 291112012445 HMMPfam hit to PF07634, RtxA repeat, score 0.0082 291112012446 HMMPfam hit to PF07634, RtxA repeat, score 0.013 291112012447 HMMPfam hit to PF07634, RtxA repeat, score 0.0093 291112012448 HMMPfam hit to PF07634, RtxA repeat, score 4 291112012449 HMMPfam hit to PF07634, RtxA repeat, score 0.0051 291112012450 HMMPfam hit to PF07634, RtxA repeat, score 0.0015 291112012451 HMMPfam hit to PF07634, RtxA repeat, score 0.062 291112012452 HMMPfam hit to PF07634, RtxA repeat, score 0.11 291112012453 PAS fold; Region: PAS_4; pfam08448 291112012454 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112012455 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112012456 DNA binding residues [nucleotide binding] 291112012457 dimerization interface [polypeptide binding]; other site 291112012458 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 6.4e-08; HMMSmart hit to SM00421, no description, score 4.3e-05 291112012459 HMMPfam hit to PF08448, PAS fold, score 4.3e-05 291112012460 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168 291112012461 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112012462 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112012463 homodimer interface [polypeptide binding]; other site 291112012464 catalytic residue [active] 291112012465 HMMPfam hit to PF00155, Aminotransferase class I and II, score 3.8e-36 291112012466 Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931 291112012467 12 probable transmembrane helices predicted for PAT0970 by TMHMM2.0 at aa 7-29, 34-56, 76-98, 108-130, 135-157, 188-210, 231-253, 258-280, 327-349, 364-386, 416-438 and 443-465 291112012468 HMMPfam hit to PF03553, Na+/H+ antiporter family, score 3e-89 291112012469 Transcriptional regulators [Transcription]; Region: PurR; COG1609 291112012470 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 291112012471 DNA binding site [nucleotide binding] 291112012472 domain linker motif; other site 291112012473 Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270 291112012474 dimerization interface (closed form) [polypeptide binding]; other site 291112012475 ligand binding site [chemical binding]; other site 291112012476 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 1.5e-09 291112012477 HMMSmart hit to SM00354, no description, score 1.2e-26 291112012478 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 2.3e-12 291112012479 PAS fold; Region: PAS_4; pfam08448 291112012480 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112012481 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112012482 DNA binding residues [nucleotide binding] 291112012483 dimerization interface [polypeptide binding]; other site 291112012484 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 7e-10; HMMSmart hit to SM00421, no description, score 4.2e-07 291112012485 HMMPfam hit to PF08448, PAS fold, score 1.8e-06 291112012486 VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173 291112012487 active site 291112012488 ADP-ribosylating toxin turn-turn motif; other site 291112012489 PAS fold; Region: PAS_4; pfam08448 291112012490 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315 291112012491 DNA binding residues [nucleotide binding] 291112012492 dimerization interface [polypeptide binding]; other site 291112012493 HMMPfam hit to PF08448, PAS fold, score 6.1e-20 291112012494 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 2e-05; HMMSmart hit to SM00421, no description, score 0.0073 291112012495 PAS fold; Region: PAS_4; pfam08448 291112012496 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112012497 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112012498 DNA binding residues [nucleotide binding] 291112012499 dimerization interface [polypeptide binding]; other site 291112012500 HMMPfam hit to PF08448, PAS fold, score 1.2e-07 291112012501 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 3.6e-10; HMMSmart hit to SM00421, no description, score 1.6e-08 291112012502 PAS fold; Region: PAS_4; pfam08448 291112012503 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112012504 DNA binding residues [nucleotide binding] 291112012505 dimerization interface [polypeptide binding]; other site 291112012506 HMMPfam hit to PF08448, PAS fold, score 0.0042 291112012507 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 2.3e-05 291112012508 Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843 291112012509 Protein of unknown function (DUF1305); Region: DUF1305; pfam06996 291112012510 HMMPfam hit to PF06996, Protein of unknown function (DUF1305), score 1.2e-37 291112012511 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 291112012512 Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947 291112012513 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 8.6e-241 291112012514 Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and vesicular transport]; Region: IcmF; COG3523 291112012515 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 291112012516 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 291112012517 3 probable transmembrane helices predicted for PAT0958 by TMHMM2.0 at aa 5-27, 47-66 and 347-369 291112012518 2 probable transmembrane helices predicted for PAT0957 by TMHMM2.0 at aa 21-39 and 49-71 291112012519 PAAR motif; Region: PAAR_motif; pfam05488 291112012520 HMMPfam hit to PF05488, PAAR motif, score 8.1e-06 291112012521 HMMPfam hit to PF05488, PAAR motif, score 5.5 291112012522 Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994 291112012523 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 291112012524 1 probable transmembrane helix predicted for PAT0954 by TMHMM2.0 at aa 9-31 291112012525 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 291112012526 1 probable transmembrane helix predicted for PAT0953 by TMHMM2.0 at aa 9-31 291112012527 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112012528 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 291112012529 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112012530 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112012531 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 291112012532 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 291112012533 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112012534 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 1e-57 291112012535 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931 291112012536 Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994 291112012537 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 291112012538 1 probable transmembrane helix predicted for PAT0946 by TMHMM2.0 at aa 9-31 291112012539 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 291112012540 1 probable transmembrane helix predicted for PAT0945 by TMHMM2.0 at aa 9-31 291112012541 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 291112012542 1 probable transmembrane helix predicted for PAT0944 by TMHMM2.0 at aa 31-53 291112012543 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112012544 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 5.7e-58 291112012545 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 291112012546 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 291112012547 ligand binding site [chemical binding]; other site 291112012548 HMMPfam hit to PF00691, OmpA family, score 2e-14 291112012549 2 probable transmembrane helices predicted for PAT0942 by TMHMM2.0 at aa 10-28 and 33-50 291112012550 type IV / VI secretion system protein, DotU family; Region: IV_VI_DotU; TIGR03349 291112012551 1 probable transmembrane helix predicted for PAT0941 by TMHMM2.0 at aa 195-217 291112012552 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 291112012553 Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936 291112012554 HMMPfam hit to PF05936, Bacterial protein of unknown function (DUF87, score 4.6e-185 291112012555 type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355 291112012556 Protein of unknown function (DUF877); Region: DUF877; pfam05943 291112012557 HMMPfam hit to PF05943, Protein of unknown function (DUF877), score 4.4e-296 291112012558 Protein of unknown function (DUF770); Region: DUF770; pfam05591 291112012559 HMMPfam hit to PF05591, Protein of unknown function (DUF770), score 2.6e-83 291112012560 PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861 291112012561 putative active site [active] 291112012562 Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002 291112012563 SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966 291112012564 Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026 291112012565 HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 3.1e-17 291112012566 Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161 291112012567 HMMPfam hit to PF02604, Phd_YefM, score 1.4e-13 291112012568 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 291112012569 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112012570 acyl-activating enzyme (AAE) consensus motif; other site 291112012571 AMP binding site [chemical binding]; other site 291112012572 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012573 Condensation domain; Region: Condensation; pfam00668 291112012574 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112012575 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112012576 acyl-activating enzyme (AAE) consensus motif; other site 291112012577 AMP binding site [chemical binding]; other site 291112012578 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012579 Condensation domain; Region: Condensation; pfam00668 291112012580 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112012581 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112012582 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112012583 acyl-activating enzyme (AAE) consensus motif; other site 291112012584 AMP binding site [chemical binding]; other site 291112012585 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012586 Condensation domain; Region: Condensation; pfam00668 291112012587 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112012588 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112012589 acyl-activating enzyme (AAE) consensus motif; other site 291112012590 AMP binding site [chemical binding]; other site 291112012591 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012592 Condensation domain; Region: Condensation; pfam00668 291112012593 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112012594 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112012595 acyl-activating enzyme (AAE) consensus motif; other site 291112012596 AMP binding site [chemical binding]; other site 291112012597 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112012598 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 291112012599 HMMPfam hit to PF00975, Thioesterase domain, score 3.3e-17 291112012600 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 4.2e-10 291112012601 HMMPfam hit to PF00501, AMP-binding enzyme, score 5.5e-157 291112012602 HMMPfam hit to PF00668, Condensation domain, score 8.1e-27 291112012603 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 3.4e-17 291112012604 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.2e-159 291112012605 HMMPfam hit to PF00668, Condensation domain, score 1.3e-26 291112012606 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.6e-17 291112012607 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.1e-163 291112012608 HMMPfam hit to PF00668, Condensation domain, score 1.6e-85 291112012609 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.2e-17 291112012610 HMMPfam hit to PF00501, AMP-binding enzyme, score 3.2e-160 291112012611 HMMPfam hit to PF00668, Condensation domain, score 5.2e-24 291112012612 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 3.9e-13 291112012613 HMMPfam hit to PF00501, AMP-binding enzyme, score 8.1e-154 291112012614 Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704 291112012615 HMMPfam hit to PF04011, LemA family, score 8.4e-42 291112012616 1 probable transmembrane helix predicted for PAT0932 by TMHMM2.0 at aa 5-27 291112012617 5 probable transmembrane helices predicted for PAT0931 by TMHMM2.0 at aa 2-21, 31-48, 55-77, 110-132 and 309-331 291112012618 LemA family; Region: LemA; cl00742 291112012619 1 probable transmembrane helix predicted for PAT0930 by TMHMM2.0 at aa 4-26 291112012620 HMMPfam hit to PF04011, LemA family, score 3.9e-23 291112012621 3 probable transmembrane helices predicted for PAT0929 by TMHMM2.0 at aa 20-41, 53-75 and 79-98 291112012622 Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654 291112012623 HMMPfam hit to PF05012, Prophage maintenance system killer protein, score 2.1e-32 291112012624 Antitoxin of toxin-antitoxin stability system N-terminal; Region: RelB_N; pfam12910 291112012625 HMMPfam hit to PF02604, Phd_YefM, score 1.2e-06 291112012626 Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880 291112012627 ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430 291112012628 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112012629 Peptidase C80 family; Region: Peptidase_C80; pfam11713 291112012630 RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931 291112012631 HMMPfam hit to PF00353, no description, score 11 291112012632 HMMPfam hit to PF07634, RtxA repeat, score 6.3 291112012633 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 0.00073 291112012634 HMMPfam hit to PF07634, RtxA repeat, score 4 291112012635 HMMPfam hit to PF07634, RtxA repeat, score 0.0011 291112012636 HMMPfam hit to PF07634, RtxA repeat, score 0.055 291112012637 HMMPfam hit to PF07634, RtxA repeat, score 0.039 291112012638 HMMPfam hit to PF07634, RtxA repeat, score 0.0011 291112012639 HMMPfam hit to PF07634, RtxA repeat, score 12 291112012640 HMMPfam hit to PF07634, RtxA repeat, score 0.051 291112012641 HMMPfam hit to PF07634, RtxA repeat, score 0.014 291112012642 HMMPfam hit to PF07634, RtxA repeat, score 0.03 291112012643 HMMPfam hit to PF07634, RtxA repeat, score 5.7 291112012644 HMMPfam hit to PF07634, RtxA repeat, score 0.47 291112012645 HMMPfam hit to PF07634, RtxA repeat, score 0.074 291112012646 HMMPfam hit to PF07634, RtxA repeat, score 0.32 291112012647 HMMPfam hit to PF07634, RtxA repeat, score 0.033 291112012648 HMMPfam hit to PF07634, RtxA repeat, score 1.7 291112012649 HMMPfam hit to PF07634, RtxA repeat, score 0.015 291112012650 HMMPfam hit to PF07634, RtxA repeat, score 0.0019 291112012651 HMMPfam hit to PF07634, RtxA repeat, score 0.00064 291112012652 HMMPfam hit to PF07634, RtxA repeat, score 0.063 291112012653 HMMPfam hit to PF07634, RtxA repeat, score 0.019 291112012654 HMMPfam hit to PF07634, RtxA repeat, score 0.01 291112012655 HMMPfam hit to PF07634, RtxA repeat, score 0.24 291112012656 HMMPfam hit to PF07634, RtxA repeat, score 0.0075 291112012657 HMMPfam hit to PF07634, RtxA repeat, score 0.042 291112012658 HMMPfam hit to PF07634, RtxA repeat, score 0.0078 291112012659 HMMPfam hit to PF07634, RtxA repeat, score 0.0081 291112012660 HMMPfam hit to PF07634, RtxA repeat, score 0.011 291112012661 HMMPfam hit to PF07634, RtxA repeat, score 0.037 291112012662 HMMPfam hit to PF07634, RtxA repeat, score 5.9 291112012663 HMMPfam hit to PF07634, RtxA repeat, score 0.012 291112012664 HMMPfam hit to PF07634, RtxA repeat, score 7.3 291112012665 HMMPfam hit to PF07634, RtxA repeat, score 0.0066 291112012666 HMMPfam hit to PF07634, RtxA repeat, score 11 291112012667 HMMPfam hit to PF07634, RtxA repeat, score 0.00022 291112012668 HMMPfam hit to PF07634, RtxA repeat, score 0.085 291112012669 HMMPfam hit to PF07634, RtxA repeat, score 0.004 291112012670 HMMPfam hit to PF07634, RtxA repeat, score 0.00037 291112012671 HMMPfam hit to PF07634, RtxA repeat, score 0.0062 291112012672 HMMPfam hit to PF07634, RtxA repeat, score 0.064 291112012673 HMMPfam hit to PF07634, RtxA repeat, score 0.009 291112012674 HMMPfam hit to PF07634, RtxA repeat, score 0.012 291112012675 HMMPfam hit to PF07634, RtxA repeat, score 0.0046 291112012676 HMMPfam hit to PF07634, RtxA repeat, score 0.0074 291112012677 HMMPfam hit to PF07634, RtxA repeat, score 1.1 291112012678 Homeodomain-like domain; Region: HTH_23; pfam13384 291112012679 Winged helix-turn helix; Region: HTH_29; pfam13551 291112012680 Winged helix-turn helix; Region: HTH_33; pfam13592 291112012681 DDE superfamily endonuclease; Region: DDE_3; pfam13358 291112012682 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335 291112012683 RTX toxin acyltransferase family; Region: HlyC; cl01131 291112012684 HMMPfam hit to PF02794, RTX toxin acyltransferase family, score 4.6e-06 291112012685 type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846 291112012686 Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296 291112012687 putative active site [active] 291112012688 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112012689 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112012690 Walker A/P-loop; other site 291112012691 ATP binding site [chemical binding]; other site 291112012692 Q-loop/lid; other site 291112012693 ABC transporter signature motif; other site 291112012694 Walker B; other site 291112012695 D-loop; other site 291112012696 H-loop/switch region; other site 291112012697 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 3.3e-39 291112012698 5 probable transmembrane helices predicted for PAT0922 by TMHMM2.0 at aa 144-166, 176-198, 251-273, 278-300 and 378-400 291112012699 HMMSmart hit to SM00382, no description, score 5.1e-19 291112012700 HMMPfam hit to PF00005, ABC transporter, score 3.1e-66 291112012701 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 291112012702 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112012703 1 probable transmembrane helix predicted for PAT0921 by TMHMM2.0 at aa 37-59 291112012704 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.1e-19 291112012705 A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39_likeD; cd02421 291112012706 type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846 291112012707 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112012708 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112012709 Walker A/P-loop; other site 291112012710 ATP binding site [chemical binding]; other site 291112012711 Q-loop/lid; other site 291112012712 ABC transporter signature motif; other site 291112012713 Walker B; other site 291112012714 D-loop; other site 291112012715 H-loop/switch region; other site 291112012716 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 1.5e-39 291112012717 4 probable transmembrane helices predicted for PAT0920 by TMHMM2.0 at aa 161-183, 193-215, 268-290 and 296-318 291112012718 HMMSmart hit to SM00382, no description, score 3.9e-19 291112012719 HMMPfam hit to PF00005, ABC transporter, score 7.6e-61 291112012720 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138 291112012721 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 291112012722 conserved cys residue [active] 291112012723 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112012724 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112012725 HMMPfam hit to PF01965, DJ-1/PfpI family, score 8.1e-06 291112012726 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix prote, score 1.2e-06 291112012727 HMMSmart hit to SM00342, no description, score 4.6e-28 291112012728 HMMSmart hit to SM00342, no description, score 1.7e-22 291112012729 HMMPfam hit to PF00165, Bacterial regulatory helix-turn-helix protei, score 4.8e-13 291112012730 LexA regulated protein; Provisional; Region: PRK11675 291112012731 HMMPfam hit to PF01402, Ribbon-helix-helix protein, copG family, score 2.3e-05 291112012732 flavodoxin FldA; Validated; Region: PRK09267 291112012733 HMMPfam hit to PF00258, Flavodoxin, score 1.9e-52 291112012734 ferric uptake regulator; Provisional; Region: fur; PRK09462 291112012735 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 291112012736 metal binding site 2 [ion binding]; metal-binding site 291112012737 putative DNA binding helix; other site 291112012738 metal binding site 1 [ion binding]; metal-binding site 291112012739 dimer interface [polypeptide binding]; other site 291112012740 structural Zn2+ binding site [ion binding]; other site 291112012741 HMMPfam hit to PF01475, Ferric uptake regulator family, score 4.6e-69 291112012742 Putative carbohydrate binding domain; Region: CHB_HEX; smart01081 291112012743 N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]; Region: Chb; COG3525 291112012744 Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838 291112012745 The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a...; Region: GH20_Sm-chitobiase-like; cd06569 291112012746 active site 291112012747 C-terminal Early set domain associated with the catalytic domain of chitobiase (also called N-acetylglucosaminidase); Region: E_set_Chitobiase_C; cd02847 291112012748 HMMPfam hit to PF03174, Chitobiase/beta-hexosaminidase C-term, score 1.1e-31 291112012749 HMMPfam hit to PF00728, Glycosyl hydrolase family 20, catalyt, score 4.5e-176 291112012750 HMMPfam hit to PF02838, Glycosyl hydrolase family 20, domain, score 2.7e-05 291112012751 HMMPfam hit to PF03173, Putative carbohydrate binding domain, score 2.5e-76 291112012752 glutaminyl-tRNA synthetase; Provisional; Region: PRK05347 291112012753 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 291112012754 active site 291112012755 HIGH motif; other site 291112012756 nucleotide binding site [chemical binding]; other site 291112012757 catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807 291112012758 KMSKS motif; other site 291112012759 tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950 291112012760 HMMPfam hit to PF03950, tRNA synthetases class I (E and Q), an, score 1.5e-100 291112012761 HMMPfam hit to PF00749, tRNA synthetases class I (E and Q), ca, score 2.6e-184 291112012762 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 291112012763 PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998 291112012764 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 291112012765 active site turn [active] 291112012766 phosphorylation site [posttranslational modification] 291112012767 PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210 291112012768 HPr interaction site; other site 291112012769 glycerol kinase (GK) interaction site [polypeptide binding]; other site 291112012770 active site 291112012771 phosphorylation site [posttranslational modification] 291112012772 HMMPfam hit to PF00358, phosphoenolpyruvate-dependent sugar phosph, score 1.8e-73 291112012773 HMMPfam hit to PF00367, phosphotransferase system, EIIB, score 8.4e-13 291112012774 8 probable transmembrane helices predicted for PAT0910 by TMHMM2.0 at aa 12-34, 49-71, 84-106, 155-177, 255-274, 284-301, 314-336 and 356-378 291112012775 HMMPfam hit to PF02378, Phosphotransferase system, EIIC, score 2.6e-83 291112012776 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363 291112012777 GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399 291112012778 active site 291112012779 trimer interface [polypeptide binding]; other site 291112012780 allosteric site; other site 291112012781 active site lid [active] 291112012782 hexamer (dimer of trimers) interface [polypeptide binding]; other site 291112012783 HMMPfam hit to PF01182, Glucosamine-6-phosphate isomerases/6-, score 3.5e-178 291112012784 N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820 291112012785 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854 291112012786 active site 291112012787 dimer interface [polypeptide binding]; other site 291112012788 HMMPfam hit to PF01979, Amidohydrolase family, score 8.7e-36 291112012789 MarR family; Region: MarR; pfam01047 291112012790 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 291112012791 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 291112012792 nucleotide binding site [chemical binding]; other site 291112012793 HMMPfam hit to PF00480, ROK family, score 4e-71 291112012794 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112012795 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 1.1e-39 291112012796 Phage Tail Collar Domain; Region: Collar; pfam07484 291112012797 HMMPfam hit to PF07484, Phage Tail Collar, score 1.2e-19 291112012798 Protein of unknown function (DUF2612); Region: DUF2612; pfam11041 291112012799 Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299 291112012800 phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644 291112012801 KilA-N domain; Region: KilA-N; pfam04383 291112012802 HMMPfam hit to PF04383, KilA, N-terminal, score 3.6e-16 291112012803 ORF6N domain; Region: ORF6N; pfam10543 291112012804 Phage-related protein [Function unknown]; Region: COG5412 291112012805 Protein of unknown function (DUF2669); Region: DUF2669; pfam10876 291112012806 Protein of unknown function (DUF3277); Region: DUF3277; pfam11681 291112012807 Protein of unknown function (DUF3383); Region: DUF3383; pfam11863 291112012808 Protein of unknown function (DUF4054); Region: DUF4054; pfam13262 291112012809 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834 291112012810 Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950 291112012811 Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979 291112012812 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3566 291112012813 Septum formation initiator; Region: DivIC; cl17659 291112012814 Uncharacterized protein, homolog of phage Mu protein gp30 [Function unknown]; Region: COG2369 291112012815 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 291112012816 HMMPfam hit to PF04233, Phage putative head morphogenesis protein, SPP1 gp7, score 8e-09 291112012817 HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 0.00029 291112012818 phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555 291112012819 Protein of unknown function (DUF1073); Region: DUF1073; pfam06381 291112012820 Phage terminase large subunit; Region: Terminase_3; cl12054 291112012821 HMMPfam hit to PF04466, Phage terminase large subunit, score 6.9e-19 291112012822 BRO family, N-terminal domain; Region: Bro-N; smart01040 291112012823 HMMPfam hit to PF02498, BRO, N-terminal, score 0.013 291112012824 Bacteriophage lysis protein; Region: Phage_lysis; pfam03245 291112012825 HMMPfam hit to PF03245, Bacteriophage lysis protein, score 6.8e-34 291112012826 Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737 291112012827 catalytic residues [active] 291112012828 HMMPfam hit to PF00959, Glycoside hydrolase, family 24, score 1.7e-30 291112012829 Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106 291112012830 HMMPfam hit to PF05106, Holin, phage lambda, score 3.2e-40 291112012831 Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530 291112012832 HMMPfam hit to PF06530, Phage antitermination Q-like, score 9.7e-48 291112012833 Bacteriophage Lambda NinG protein; Region: NinG; pfam05766 291112012834 HMMPfam hit to PF05766, Bacteriophage Lambda NinG, score 1.7e-93 291112012835 Protein of unknown function (DUF1367); Region: DUF1367; pfam07105 291112012836 HMMPfam hit to PF07105, Protein of unknown function DUF1367, score 2.8e-08 291112012837 HMMPfam hit to PF07105, Protein of unknown function DUF1367, score 3.6e-08 291112012838 Replication protein P; Region: Phage_lambda_P; pfam06992 291112012839 HMMPfam hit to PF06992, Replication P, score 5e-76 291112012840 Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492 291112012841 HMMPfam hit to PF04492, Phage replication protein O, N-terminal, score 7.4e-85 291112012842 Bacteriophage CII protein; Region: Phage_CII; pfam05269 291112012843 HMMPfam hit to PF05269, Bacteriophage CII protein, score 0.0012 291112012844 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112012845 non-specific DNA binding site [nucleotide binding]; other site 291112012846 salt bridge; other site 291112012847 sequence-specific DNA binding site [nucleotide binding]; other site 291112012848 HMMSmart hit to SM00530, no description, score 6.3e-06 291112012849 HMMPfam hit to PF01381, Helix-turn-helix, score 3.2e-09 291112012850 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112012851 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112012852 non-specific DNA binding site [nucleotide binding]; other site 291112012853 salt bridge; other site 291112012854 sequence-specific DNA binding site [nucleotide binding]; other site 291112012855 HMMSmart hit to SM00530, no description, score 1.2e-13 291112012856 HMMPfam hit to PF01381, Helix-turn-helix, score 5.5e-15 291112012857 Protein of unknown function (DUF4065); Region: DUF4065; cl01445 291112012858 2 probable transmembrane helices predicted for PAT0817 by TMHMM2.0 at aa 69-91 and 96-118 291112012859 DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012 291112012860 active site 291112012861 catalytic site [active] 291112012862 substrate binding site [chemical binding]; other site 291112012863 Protein of unknown function (DUF3268); Region: DUF3268; pfam11672 291112012864 DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869 291112012865 HMMPfam hit to PF05869, DNA N-6-adenine-methyltransferase (Dam), score 2.7e-72 291112012866 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112012867 active site 291112012868 DNA binding site [nucleotide binding] 291112012869 Int/Topo IB signature motif; other site 291112012870 HMMPfam hit to PF00589, Phage integrase family, score 0.00032 291112012871 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020 291112012872 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314 291112012873 HMMPfam hit to PF01494, FAD binding domain, score 1.8e-08 291112012874 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 4.4e-05 291112012875 (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325 291112012876 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 291112012877 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112012878 FeS/SAM binding site; other site 291112012879 TRAM domain; Region: TRAM; pfam01938 291112012880 HMMPfam hit to PF00919, Uncharacterized protein family UPF0004, score 8.9e-49 291112012881 HMMSmart hit to SM00729, no description, score 8.4e-63 291112012882 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.4e-31 291112012883 HMMPfam hit to PF01938, TRAM domain, score 9.2e-23 291112012884 Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702 291112012885 PhoH-like protein; Region: PhoH; pfam02562 291112012886 HMMPfam hit to PF02562, PhoH-like protein, score 2.1e-149 291112012887 metal-binding heat shock protein; Provisional; Region: PRK00016 291112012888 HMMPfam hit to PF02130, Uncharacterized protein family UPF0054, score 3.4e-52 291112012889 magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094 291112012890 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 291112012891 Transporter associated domain; Region: CorC_HlyC; smart01091 291112012892 HMMPfam hit to PF00571, CBS domain pair, score 5.2e-29 291112012893 HMMSmart hit to SM00116, no description, score 5.6 291112012894 HMMSmart hit to SM00116, no description, score 1.6 291112012895 HMMPfam hit to PF03471, Transporter associated domain, score 8.4e-29 291112012896 apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302 291112012897 Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571 291112012898 putative active site [active] 291112012899 catalytic triad [active] 291112012900 putative dimer interface [polypeptide binding]; other site 291112012901 8 probable transmembrane helices predicted for PAT0749 by TMHMM2.0 at aa 12-29, 33-50, 57-79, 89-111, 124-143, 163-185, 192-209 and 485-504 291112012902 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 4.2e-33 291112012903 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 291112012904 Uncharacterized conserved protein [Function unknown]; Region: COG2128 291112012905 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 4.6e-23 291112012906 glutamate and aspartate transporter subunit; Provisional; Region: PRK10797 291112012907 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112012908 substrate binding pocket [chemical binding]; other site 291112012909 membrane-bound complex binding site; other site 291112012910 hinge residues; other site 291112012911 1 probable transmembrane helix predicted for PAT0752 by TMHMM2.0 at aa 21-38 291112012912 HMMSmart hit to SM00062, no description, score 9.3e-61 291112012913 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 4.2e-47 291112012914 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 291112012915 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112012916 dimer interface [polypeptide binding]; other site 291112012917 conserved gate region; other site 291112012918 putative PBP binding loops; other site 291112012919 ABC-ATPase subunit interface; other site 291112012920 6 probable transmembrane helices predicted for PAT0753 by TMHMM2.0 at aa 5-27, 31-53, 66-88, 108-127, 179-196 and 211-233 291112012921 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 2.1e-36 291112012922 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112012923 dimer interface [polypeptide binding]; other site 291112012924 conserved gate region; other site 291112012925 putative PBP binding loops; other site 291112012926 ABC-ATPase subunit interface; other site 291112012927 5 probable transmembrane helices predicted for PAT0754 by TMHMM2.0 at aa 15-37, 58-80, 95-112, 144-166 and 197-219 291112012928 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 1.9e-27 291112012929 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 291112012930 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 291112012931 Walker A/P-loop; other site 291112012932 ATP binding site [chemical binding]; other site 291112012933 Q-loop/lid; other site 291112012934 ABC transporter signature motif; other site 291112012935 Walker B; other site 291112012936 D-loop; other site 291112012937 H-loop/switch region; other site 291112012938 HMMSmart hit to SM00382, no description, score 3.3e-12 291112012939 HMMPfam hit to PF00005, ABC transporter, score 3.2e-63 291112012940 leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390 291112012941 catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812 291112012942 HIGH motif; other site 291112012943 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 291112012944 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 291112012945 active site 291112012946 KMSKS motif; other site 291112012947 Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958 291112012948 tRNA binding surface [nucleotide binding]; other site 291112012949 HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 6.3e-14 291112012950 HMMPfam hit to PF08264, Anticodon-binding domain, score 1.9e-06 291112012951 LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796 291112012952 1 probable transmembrane helix predicted for PAT0757 by TMHMM2.0 at aa 5-27 291112012953 HMMPfam hit to PF04390, Rare lipoprotein B family, score 1.1e-60 291112012954 DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574 291112012955 DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144 291112012956 HMMPfam hit to PF06144, DNA polymerase III, delta subunit, score 3.5e-112 291112012957 nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071 291112012958 Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165 291112012959 active site 291112012960 (T/H)XGH motif; other site 291112012961 HMMPfam hit to PF01467, Cytidylyltransferase, score 4.2e-55 291112012962 ribosome-associated protein; Provisional; Region: PRK11538 291112012963 HMMPfam hit to PF02410, Domain of unknown function DUF143, score 2.6e-44 291112012964 rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246 291112012965 HMMPfam hit to PF02590, Uncharacterized ACR, COG1576, score 2.2e-78 291112012966 penicillin-binding protein 2; Provisional; Region: PRK10795 291112012967 Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717 291112012968 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 291112012969 1 probable transmembrane helix predicted for PAT0762 by TMHMM2.0 at aa 21-43 291112012970 HMMPfam hit to PF03717, Penicillin-binding Protein dimerisatio, score 4.1e-62 291112012971 HMMPfam hit to PF00905, Penicillin binding protein transpeptid, score 6.9e-93 291112012972 cell wall shape-determining protein; Provisional; Region: PRK10794 291112012973 9 probable transmembrane helices predicted for PAT0763 by TMHMM2.0 at aa 15-37, 50-68, 73-95, 136-155, 160-177, 184-206, 272-294, 306-328 and 338-360 291112012974 HMMPfam hit to PF01098, Cell cycle protein, score 3.5e-170 291112012975 rare lipoprotein A; Provisional; Region: PRK10672 291112012976 Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330 291112012977 Sporulation related domain; Region: SPOR; pfam05036 291112012978 HMMPfam hit to PF03330, Rare lipoprotein A (RlpA)-like double-psi be, score 2e-37 291112012979 HMMPfam hit to PF05036, Sporulation related domain, score 6.2e-16 291112012980 D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793 291112012981 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872 291112012982 Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943 291112012983 HMMPfam hit to PF00768, D-alanyl-D-alanine carboxypeptidase, score 1.1e-140 291112012984 HMMPfam hit to PF07943, Penicillin-binding protein 5, C-termina, score 8.8e-39 291112012985 hypothetical protein; Provisional; Region: PRK04998 291112012986 HMMPfam hit to PF04359, Protein of unknown function (DUF493), score 2.4e-51 291112012987 lipoate-protein ligase B; Provisional; Region: PRK14342 291112012988 HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 3.8e-13 291112012989 lipoyl synthase; Provisional; Region: PRK05481 291112012990 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112012991 FeS/SAM binding site; other site 291112012992 HMMSmart hit to SM00729, no description, score 2.2e-17 291112012993 HMMPfam hit to PF04055, Radical SAM superfamily, score 6.1e-25 291112012994 chromosome condensation membrane protein; Provisional; Region: PRK14196 291112012995 4 probable transmembrane helices predicted for PAT0769 by TMHMM2.0 at aa 4-26, 33-55, 70-92 and 99-121 291112012996 HMMPfam hit to PF02537, CrcB-like protein, score 1.9e-38 291112012997 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 291112012998 DNA-binding site [nucleotide binding]; DNA binding site 291112012999 RNA-binding motif; other site 291112013000 HMMPfam hit to PF00313, 'Cold-shock' DNA-binding domain, score 2.8e-43 291112013001 HMMSmart hit to SM00357, no description, score 4.5e-33 291112013002 methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901 291112013003 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870 291112013004 The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445 291112013005 DNA binding site [nucleotide binding] 291112013006 active site 291112013007 HMMPfam hit to PF01035, 6-O-methylguanine DNA methyltransfera, score 1.4e-36 291112013008 HMMPfam hit to PF02870, 6-O-methylguanine DNA methyltransfera, score 0.0013 291112013009 NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976 291112013010 catalytic residues [active] 291112013011 HMMPfam hit to PF00462, Glutaredoxin, score 6.7e-16 291112013012 ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600 291112013013 HMMPfam hit to PF07972, NrdI Flavodoxin like, score 4.3e-71 291112013014 ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188 291112013015 Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343 291112013016 Class I ribonucleotide reductase; Region: RNR_I; cd01679 291112013017 active site 291112013018 dimer interface [polypeptide binding]; other site 291112013019 catalytic residues [active] 291112013020 effector binding site; other site 291112013021 R2 peptide binding site; other site 291112013022 HMMPfam hit to PF08343, Ribonucleotide reductase N-terminal, score 5.2e-45 291112013023 HMMPfam hit to PF00317, Ribonucleotide reductase, all-alpha d, score 4.7e-26 291112013024 HMMPfam hit to PF02867, Ribonucleotide reductase, barrel doma, score 3.2e-209 291112013025 ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966 291112013026 Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049 291112013027 dimer interface [polypeptide binding]; other site 291112013028 putative radical transfer pathway; other site 291112013029 diiron center [ion binding]; other site 291112013030 tyrosyl radical; other site 291112013031 HMMPfam hit to PF00268, Ribonucleotide reductase, small chain, score 6.4e-93 291112013032 glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070 291112013033 ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294 291112013034 Walker A/P-loop; other site 291112013035 ATP binding site [chemical binding]; other site 291112013036 Q-loop/lid; other site 291112013037 ABC transporter signature motif; other site 291112013038 Walker B; other site 291112013039 D-loop; other site 291112013040 H-loop/switch region; other site 291112013041 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583 291112013042 HMMSmart hit to SM00382, no description, score 3.7e-19 291112013043 HMMPfam hit to PF00005, ABC transporter, score 1e-62 291112013044 HMMPfam hit to PF00571, CBS domain pair, score 1.1e-09 291112013045 glycine betaine transporter membrane protein; Provisional; Region: PRK10952 291112013046 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112013047 dimer interface [polypeptide binding]; other site 291112013048 conserved gate region; other site 291112013049 putative PBP binding loops; other site 291112013050 ABC-ATPase subunit interface; other site 291112013051 5 probable transmembrane helices predicted for PAT0778 by TMHMM2.0 at aa 125-147, 153-175, 196-218, 274-296 and 303-325 291112013052 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 8e-33 291112013053 glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119 291112013054 Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069 291112013055 HMMPfam hit to PF04069, Substrate binding domain of ABC-type glycine, score 1.1e-58 291112013056 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 291112013057 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112013058 putative substrate translocation pore; other site 291112013059 12 probable transmembrane helices predicted for PAT0780 by TMHMM2.0 at aa 13-35, 50-72, 79-98, 108-130, 137-156, 166-188, 219-241, 245-267, 280-299, 303-322, 339-361 and 366-388 291112013060 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 8.8e-42 291112013061 Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296 291112013062 5 probable transmembrane helices predicted for PAT0781 by TMHMM2.0 at aa 21-43, 58-80, 142-164, 174-193 and 206-228 291112013063 HMMPfam hit to PF03591, AzlC protein, score 5.3e-58 291112013064 putative L-valine exporter; Provisional; Region: PRK10408 291112013065 4 probable transmembrane helices predicted for PAT0782 by TMHMM2.0 at aa 4-23, 43-62, 72-87 and 92-111 291112013066 transcriptional repressor MprA; Provisional; Region: PRK10870 291112013067 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 291112013068 HMMSmart hit to SM00347, no description, score 1.1e-30 291112013069 HMMPfam hit to PF01047, MarR family, score 5e-25 291112013070 multidrug efflux system protein EmrA; Provisional; Region: PRK15136 291112013071 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112013072 1 probable transmembrane helix predicted for PAT0784 by TMHMM2.0 at aa 24-46 291112013073 HMMPfam hit to PF00529, HlyD family secretion protein, score 8e-71 291112013074 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 291112013075 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112013076 putative substrate translocation pore; other site 291112013077 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112013078 13 probable transmembrane helices predicted for PAT0785 by TMHMM2.0 at aa 13-35, 50-72, 79-101, 105-127, 139-161, 166-183, 203-220, 233-250, 271-290, 300-322, 334-353, 368-390 and 479-497 291112013079 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.2e-56 291112013080 putative methyltransferase; Provisional; Region: PRK10864 291112013081 RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032 291112013082 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 291112013083 HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 8.3e-36 291112013084 HMMPfam hit to PF08032, RNA 2'-O ribose methyltransferase subs, score 4e-13 291112013085 Uncharacterized conserved protein [Function unknown]; Region: COG3148 291112013086 HMMPfam hit to PF03942, DTW domain, score 7e-59 291112013087 Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042 291112013088 CoA binding domain; Region: CoA_binding_2; pfam13380 291112013089 Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607 291112013090 ATP-grasp domain; Region: ATP-grasp_5; pfam13549 291112013091 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 291112013092 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 291112013093 HMMPfam hit to PF02629, CoA binding domain, score 7.8e-05 291112013094 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.6e-10 291112013095 phosphatidylserine synthase; Provisional; Region: pssA; PRK09428 291112013096 Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134 291112013097 domain interface [polypeptide binding]; other site 291112013098 putative active site [active] 291112013099 catalytic site [active] 291112013100 Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136 291112013101 domain interface [polypeptide binding]; other site 291112013102 putative active site [active] 291112013103 catalytic site [active] 291112013104 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 8.7e-05; HMMSmart hit to SM00155, no description, score 0.085 291112013105 HMMPfam hit to PF00614, Phospholipase D Active site motif, score 4.9e-06; HMMSmart hit to SM00155, no description, score 0.0055 291112013106 protein disaggregation chaperone; Provisional; Region: PRK10865 291112013107 Clp amino terminal domain; Region: Clp_N; pfam02861 291112013108 Clp amino terminal domain; Region: Clp_N; pfam02861 291112013109 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112013110 Walker A motif; other site 291112013111 ATP binding site [chemical binding]; other site 291112013112 Walker B motif; other site 291112013113 arginine finger; other site 291112013114 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112013115 Walker A motif; other site 291112013116 ATP binding site [chemical binding]; other site 291112013117 Walker B motif; other site 291112013118 arginine finger; other site 291112013119 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 291112013120 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 3.8e-113 291112013121 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 4.1e-06 291112013122 HMMSmart hit to SM00382, no description, score 9.2e-11 291112013123 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 5.8e-12 291112013124 HMMSmart hit to SM00382, no description, score 1.1e-10 291112013125 HMMPfam hit to PF02861, Clp amino terminal domain, score 6.1e-14 291112013126 HMMPfam hit to PF02861, Clp amino terminal domain, score 2.7e-13 291112013127 hypothetical protein; Provisional; Region: PRK10723 291112013128 Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496 291112013129 HMMPfam hit to PF02578, Uncharacterised ACR, YfiH family COG1496, score 2.2e-84 291112013130 23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180 291112013131 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 291112013132 RNA binding surface [nucleotide binding]; other site 291112013133 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 291112013134 active site 291112013135 HMMPfam hit to PF00849, RNA pseudouridylate synthase, score 5.3e-67 291112013136 HMMSmart hit to SM00363, no description, score 1.8e-11 291112013137 HMMPfam hit to PF01479, S4 domain, score 2.4e-13 291112013138 outer membrane biogenesis protein BamD; Provisional; Region: PRK10866 291112013139 RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552 291112013140 30S subunit binding site; other site 291112013141 HMMPfam hit to PF02482, Sigma 54 modulation protein / S30EA r, score 2.8e-37 291112013142 bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622 291112013143 chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797 291112013144 Prephenate dehydratase; Region: PDT; pfam00800 291112013145 C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905 291112013146 putative L-Phe binding site [chemical binding]; other site 291112013147 HMMPfam hit to PF01817, Chorismate mutase type II, score 1.6e-26 291112013148 HMMPfam hit to PF00800, Prephenate dehydratase, score 1.1e-94 291112013149 H-NS histone family; Region: Histone_HNS; pfam00816 291112013150 Domain in histone-like proteins of HNS family; Region: HNS; smart00528 291112013151 HMMPfam hit to PF00816, H-NS histone family, score 2.9e-08 291112013152 HMMSmart hit to SM00528, no description, score 5.8e-09 291112013153 bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199 291112013154 Chorismate mutase type II; Region: CM_2; cl00693 291112013155 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232 291112013156 prephenate dehydrogenase; Validated; Region: PRK08507 291112013157 HMMPfam hit to PF02153, Prephenate dehydrogenase, score 8.1e-19 291112013158 HMMPfam hit to PF01817, Chorismate mutase type II, score 5e-33 291112013159 phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755 291112013160 DAHP synthetase I family; Region: DAHP_synth_1; pfam00793 291112013161 HMMPfam hit to PF00793, DAHP synthetase I family, score 1.6e-150 291112013162 3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427 291112013163 homoserine O-acetyltransferase; Provisional; Region: metX; cl17114 291112013164 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 4.7e-22 291112013165 50S ribosomal protein L19; Provisional; Region: rplS; PRK05338 291112013166 HMMPfam hit to PF01245, Ribosomal protein L19, score 6.9e-80 291112013167 tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026 291112013168 HMMPfam hit to PF01746, tRNA (Guanine-1)-methyltransferase, score 1.4e-83 291112013169 16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122 291112013170 RimM N-terminal domain; Region: RimM; pfam01782 291112013171 PRC-barrel domain; Region: PRC; pfam05239 291112013172 HMMPfam hit to PF05239, PRC-barrel domain, score 1.8e-13 291112013173 HMMPfam hit to PF01782, RimM N-terminal domain, score 1.5e-32 291112013174 30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040 291112013175 HMMPfam hit to PF00886, Ribosomal protein S16, score 4.6e-32 291112013176 signal recognition particle protein; Provisional; Region: PRK10867 291112013177 SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963 291112013178 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 291112013179 P loop; other site 291112013180 GTP binding site [chemical binding]; other site 291112013181 Signal peptide binding domain; Region: SRP_SPB; pfam02978 291112013182 HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 2.3e-119 291112013183 HMMSmart hit to SM00382, no description, score 6.8e-08 291112013184 HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 3.1e-32 291112013185 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137 291112013186 8 probable transmembrane helices predicted for PAT0806 by TMHMM2.0 at aa 3-25, 30-49, 62-84, 89-111, 123-145, 175-197, 209-226 and 236-253 291112013187 HMMPfam hit to PF01578, Cytochrome C assembly protein, score 9.9e-63 291112013188 hypothetical protein; Provisional; Region: PRK11573 291112013189 Domain of unknown function DUF21; Region: DUF21; pfam01595 291112013190 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 291112013191 Transporter associated domain; Region: CorC_HlyC; smart01091 291112013192 4 probable transmembrane helices predicted for PAT0807 by TMHMM2.0 at aa 4-26, 62-84, 89-111 and 124-146 291112013193 HMMPfam hit to PF01595, Domain of unknown function DUF21, score 3.4e-68 291112013194 HMMPfam hit to PF00571, CBS domain pair, score 5e-15 291112013195 HMMPfam hit to PF03471, Transporter associated domain, score 1.4e-22 291112013196 S-ribosylhomocysteinase; Provisional; Region: PRK02260 291112013197 HMMPfam hit to PF02664, S-Ribosylhomocysteinase (LuxS), score 2.8e-108 291112013198 glutamate--cysteine ligase; Provisional; Region: PRK02107 291112013199 HMMPfam hit to PF04262, Glutamate-cysteine ligase, score 3.8e-249 291112013200 carbon storage regulator; Provisional; Region: PRK01712 291112013201 HMMPfam hit to PF02599, Global regulator protein family, score 1.3e-32 291112013202 alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252 291112013203 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673 291112013204 motif 1; other site 291112013205 active site 291112013206 motif 2; other site 291112013207 motif 3; other site 291112013208 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 291112013209 DHHA1 domain; Region: DHHA1; pfam02272 291112013210 HMMPfam hit to PF02272, DHHA1 domain, score 7.1e-22 291112013211 HMMPfam hit to PF07973, Threonyl and Alanyl tRNA synthetase seco, score 2.4e-20 291112013212 HMMPfam hit to PF01411, tRNA synthetases class II (A), score 0 291112013213 recombinase A; Provisional; Region: recA; PRK09354 291112013214 RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983 291112013215 hexamer interface [polypeptide binding]; other site 291112013216 Walker A motif; other site 291112013217 ATP binding site [chemical binding]; other site 291112013218 Walker B motif; other site 291112013219 HMMPfam hit to PF00154, recA bacterial DNA recombination protein, score 2.5e-243 291112013220 HMMSmart hit to SM00382, no description, score 9.3e-09 291112013221 hypothetical protein; Validated; Region: PRK03661 291112013222 HMMPfam hit to PF02464, Competence-damaged protein, score 1.6e-79 291112013223 lysophospholipid transporter LplT; Provisional; Region: PRK11195 291112013224 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112013225 putative substrate translocation pore; other site 291112013226 11 probable transmembrane helices predicted for PAT0011 by TMHMM2.0 at aa 19-41, 51-73, 94-116, 136-158, 163-185, 227-249, 256-278, 282-301, 306-328, 343-365 and 372-394 291112013227 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.3e-18 291112013228 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 291112013229 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 291112013230 putative acyl-acceptor binding pocket; other site 291112013231 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112013232 AMP-binding enzyme; Region: AMP-binding; pfam00501 291112013233 acyl-activating enzyme (AAE) consensus motif; other site 291112013234 active site 291112013235 AMP binding site [chemical binding]; other site 291112013236 CoA binding site [chemical binding]; other site 291112013237 HMMPfam hit to PF00501, AMP-binding enzyme, score 6.6e-50 291112013238 1 probable transmembrane helix predicted for PAT0012 by TMHMM2.0 at aa 416-438 291112013239 HMMSmart hit to SM00563, no description, score 2.3e-21 291112013240 HMMPfam hit to PF01553, Acyltransferase, score 4.7e-23 291112013241 Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464 291112013242 Shikimate kinase; Region: SKI; pfam01202 291112013243 ADP binding site [chemical binding]; other site 291112013244 magnesium binding site [ion binding]; other site 291112013245 putative shikimate binding site; other site 291112013246 HMMPfam hit to PF01202, Shikimate kinase, score 2.5e-68 291112013247 Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079 291112013248 gamma-glutamyl phosphate reductase; Region: proA; TIGR00407 291112013249 putative catalytic cysteine [active] 291112013250 HMMPfam hit to PF00171, Aldehyde dehydrogenase family, score 3e-07 291112013251 gamma-glutamyl kinase; Provisional; Region: PRK05429 291112013252 AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242 291112013253 nucleotide binding site [chemical binding]; other site 291112013254 homotetrameric interface [polypeptide binding]; other site 291112013255 putative phosphate binding site [ion binding]; other site 291112013256 putative allosteric binding site; other site 291112013257 PUA domain; Region: PUA; pfam01472 291112013258 HMMSmart hit to SM00359, no description, score 1.7e-17 291112013259 HMMPfam hit to PF01472, PUA domain, score 2.1e-25 291112013260 HMMPfam hit to PF00696, Amino acid kinase family, score 1.3e-60 291112013261 fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077 291112013262 HMMPfam hit to PF06500, Alpha/beta hydrolase of unknown function (DU, score 2.1e-230 291112013263 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112013264 active site 291112013265 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 7.9e-20 291112013266 Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893 291112013267 M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890 291112013268 metal binding site [ion binding]; metal-binding site 291112013269 dimer interface [polypeptide binding]; other site 291112013270 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 2.6e-06 291112013271 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 1.8e-14 291112013272 DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586 291112013273 active site 291112013274 DNA polymerase IV; Validated; Region: PRK02406 291112013275 DNA binding site [nucleotide binding] 291112013276 HMMPfam hit to PF00817, impB/mucB/samB family, score 1.7e-114 291112013277 TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785 291112013278 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 291112013279 N-terminal plug; other site 291112013280 ligand-binding site [chemical binding]; other site 291112013281 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 3.2e-18 291112013282 HMMPfam hit to PF00593, TonB dependent receptor, score 9.2e-23 291112013283 RNA polymerase sigma factor; Provisional; Region: PRK12528 291112013284 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 291112013285 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 291112013286 DNA binding residues [nucleotide binding] 291112013287 HMMPfam hit to PF04542, Sigma-70 region, score 2.3e-10 291112013288 HMMPfam hit to PF08281, Sigma-70, region, score 4.2e-13 291112013289 HMMPfam hit to PF04545, Sigma-70, region, score 2.5e-06 291112013290 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 291112013291 Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial protein Rv2277c and similar proteins; Region: GDPD_Rv2277c_like; cd08580 291112013292 putative active site [active] 291112013293 catalytic site [active] 291112013294 putative metal binding site [ion binding]; other site 291112013295 HMMPfam hit to PF03009, Glycerophosphoryl diester phosphodiesterase, score 1.2e-22 291112013296 Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519 291112013297 active site flap/lid [active] 291112013298 nucleophilic elbow; other site 291112013299 catalytic triad [active] 291112013300 HMMPfam hit to PF01764, Lipase (class 3), score 5.5e-23 291112013301 Protein of unknown function (DUF1044); Region: DUF1044; cl01955 291112013302 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112013303 non-specific DNA binding site [nucleotide binding]; other site 291112013304 salt bridge; other site 291112013305 sequence-specific DNA binding site [nucleotide binding]; other site 291112013306 HMMSmart hit to SM00530, no description, score 6.9e-05 291112013307 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 291112013308 PAS domain; Region: PAS_9; pfam13426 291112013309 putative active site [active] 291112013310 heme pocket [chemical binding]; other site 291112013311 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 291112013312 PAS domain; Region: PAS_9; pfam13426 291112013313 putative active site [active] 291112013314 heme pocket [chemical binding]; other site 291112013315 psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974 291112013316 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112013317 Walker A motif; other site 291112013318 ATP binding site [chemical binding]; other site 291112013319 Walker B motif; other site 291112013320 arginine finger; other site 291112013321 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis fam, score 0.0015 291112013322 HMMPfam hit to PF00158, Sigma-54 interaction domain, score 1.4e-150 291112013323 HMMPfam hit to PF07728, ATPase family associated with various, score 0.00073 291112013324 HMMSmart hit to SM00382, no description, score 2.7e-14 291112013325 HMMPfam hit to PF08448, PAS fold, score 1.2e-05 291112013326 HMMSmart hit to SM00086, no description, score 0.002 291112013327 HMMPfam hit to PF00989, PAS fold, score 5.8e-09 291112013328 HMMSmart hit to SM00091, no description, score 2.3 291112013329 HMMPfam hit to PF00989, PAS fold, score 0.097 291112013330 HMMSmart hit to SM00091, no description, score 2.6e-05 291112013331 MSMEG_0572 family protein; Region: MSMEG_0572_fam; TIGR04044 291112013332 Predicted amidohydrolase [General function prediction only]; Region: COG0388 291112013333 Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564 291112013334 putative active site [active] 291112013335 catalytic triad [active] 291112013336 putative dimer interface [polypeptide binding]; other site 291112013337 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 2.9e-47 291112013338 radical SAM protein, MSMEG_0568 family; Region: rSAM_MSMEG_0568; TIGR04043 291112013339 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112013340 FeS/SAM binding site; other site 291112013341 HMMSmart hit to SM00729, no description, score 4.3e-07 291112013342 HMMPfam hit to PF04055, Radical SAM superfamily, score 1.2e-12 291112013343 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112013344 Coenzyme A binding pocket [chemical binding]; other site 291112013345 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 8.3e-09 291112013346 AIR synthase-related protein, sll0787 family; Region: AIR_rel_sll0787; TIGR04049 291112013347 AIR synthase (PurM) related protein, subgroup 3 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two...; Region: PurM-like3; cd02192 291112013348 dimerization interface [polypeptide binding]; other site 291112013349 putative ATP binding site [chemical binding]; other site 291112013350 HMMPfam hit to PF00586, AIR synthase related protein, N-terminal dom, score 9.5e-07 291112013351 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 6.2e-12 291112013352 MSMEG_0570 family protein; Region: MSMEG_0570_fam; TIGR04042 291112013353 flavin-dependent oxidoreductase, MSMEG_0569 family; Region: MSMEG_0569_nitr; TIGR04046 291112013354 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 291112013355 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 0.0012 291112013356 Methyltransferase domain; Region: Methyltransf_31; pfam13847 291112013357 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112013358 S-adenosylmethionine binding site [chemical binding]; other site 291112013359 HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 0.00011 291112013360 HMMPfam hit to PF08241, Methyltransferase domain, score 5.3e-17 291112013361 HMMPfam hit to PF08242, Methyltransferase domain, score 9.4e-15 291112013362 1 probable transmembrane helix predicted for PAT0043 by TMHMM2.0 at aa 7-29 291112013363 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112013364 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 1.2e-51 291112013365 3 probable transmembrane helices predicted for PAT0045 by TMHMM2.0 at aa 13-35, 45-67 and 80-102 291112013366 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112013367 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 4e-45 291112013368 3 probable transmembrane helices predicted for PAT0046 by TMHMM2.0 at aa 7-26, 41-63 and 83-102 291112013369 Protein of unknown function (DUF1240); Region: DUF1240; pfam06836 291112013370 HMMPfam hit to PF06836, Protein of unknown function (DUF1240), score 1.5e-42 291112013371 3 probable transmembrane helices predicted for PAT0047 by TMHMM2.0 at aa 21-40, 60-82 and 95-117 291112013372 Protein of unknown function (DUF1778); Region: DUF1778; pfam08681 291112013373 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 291112013374 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 291112013375 Coenzyme A binding pocket [chemical binding]; other site 291112013376 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.6e-05 291112013377 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2991 291112013378 HMMPfam hit to PF04400, Protein of unknown function (DUF539), score 3.2e-22 291112013379 1 probable transmembrane helix predicted for PAT0051 by TMHMM2.0 at aa 4-23 291112013380 Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477 291112013381 ApbE family; Region: ApbE; pfam02424 291112013382 HMMPfam hit to PF02424, ApbE family, score 1.9e-117 291112013383 1 probable transmembrane helix predicted for PAT0052 by TMHMM2.0 at aa 5-24 291112013384 Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464 291112013385 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 291112013386 catalytic loop [active] 291112013387 iron binding site [ion binding]; other site 291112013388 Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188 291112013389 FAD binding pocket [chemical binding]; other site 291112013390 FAD binding motif [chemical binding]; other site 291112013391 phosphate binding motif [ion binding]; other site 291112013392 beta-alpha-beta structure motif; other site 291112013393 NAD binding pocket [chemical binding]; other site 291112013394 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 3.9e-22 291112013395 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 0.00044 291112013396 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding doma, score 6.7e-11 291112013397 1 probable transmembrane helix predicted for PAT0053 by TMHMM2.0 at aa 3-25 291112013398 Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830 291112013399 HMMPfam hit to PF02508, Rnf-Nqr subunit, membrane protein, score 1.2e-115 291112013400 6 probable transmembrane helices predicted for PAT0054 by TMHMM2.0 at aa 12-31, 41-63, 76-98, 108-130, 139-161 and 176-196 291112013401 Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292 291112013402 5 probable transmembrane helices predicted for PAT0055 by TMHMM2.0 at aa 40-62, 69-91, 101-121, 134-156 and 176-198 291112013403 HMMPfam hit to PF02508, Rnf-Nqr subunit, membrane protein, score 5.6e-96 291112013404 Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346 291112013405 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938 291112013406 HMMPfam hit to PF04205, FMN-binding domain, score 9.8e-25 291112013407 1 probable transmembrane helix predicted for PAT0056 by TMHMM2.0 at aa 15-37 291112013408 Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349 291112013409 HMMPfam hit to PF03116, NQR2, RnfD, RnfE family, score 3.7e-198 291112013410 8 probable transmembrane helices predicted for PAT0057 by TMHMM2.0 at aa 58-80, 125-147, 159-181, 268-290, 297-319, 323-345, 358-375 and 379-401 291112013411 Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352 291112013412 NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973 291112013413 HMMPfam hit to PF05896, Na(+)-translocating NADH-quinone reductase s, score 1.8e-291 291112013414 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034 291112013415 HMMPfam hit to PF06104, Bacterial protein of unknown function (DUF94, score 9.2e-112 291112013416 Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121 291112013417 Glutamine amidotransferases class-II (Gn-AT)_YafJ-type. YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea. YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908 291112013418 putative active site [active] 291112013419 putative dimer interface [polypeptide binding]; other site 291112013420 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 1.8e-26 291112013421 Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006 291112013422 dimer interface [polypeptide binding]; other site 291112013423 active site 291112013424 acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463 291112013425 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 291112013426 active site 291112013427 Domain of unknown function (DUF1974); Region: DUF1974; pfam09317 291112013428 2 probable transmembrane helices predicted for PAT0063 by TMHMM2.0 at aa 4-21 and 28-50 291112013429 HMMPfam hit to PF00441, Acyl-CoA dehydrogenase, C-terminal doma, score 1e-05 291112013430 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112013431 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112013432 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 291112013433 putative effector binding pocket; other site 291112013434 dimerization interface [polypeptide binding]; other site 291112013435 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.9e-17 291112013436 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.2e-43 291112013437 6 probable transmembrane helices predicted for PAT0067 by TMHMM2.0 at aa 2-24, 39-61, 68-90, 94-116, 129-148 and 152-174 291112013438 4 probable transmembrane helices predicted for PAT0068 by TMHMM2.0 at aa 12-34, 49-71, 83-105 and 115-133 291112013439 trans-homoaconitate synthase; Reviewed; Region: aksA; PRK11858 291112013440 Cupin domain; Region: Cupin_2; pfam07883 291112013441 HMMPfam hit to PF07883, Cupin domain, score 0.0037 291112013442 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112013443 1 probable transmembrane helix predicted for PAT0071 by TMHMM2.0 at aa 13-32 291112013444 diaminopimelate decarboxylase; Provisional; Region: PRK11165 291112013445 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828 291112013446 active site 291112013447 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 291112013448 substrate binding site [chemical binding]; other site 291112013449 catalytic residues [active] 291112013450 dimer interface [polypeptide binding]; other site 291112013451 HMMPfam hit to PF00278, Pyridoxal-dependent decarboxylase, C-, score 3.1e-40 291112013452 HMMPfam hit to PF02784, Pyridoxal-dependent decarboxylase, py, score 5.2e-65 291112013453 REGION 21-20 291112013454 DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013 291112013455 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112013456 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 291112013457 dimerization interface [polypeptide binding]; other site 291112013458 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-15 291112013459 HMMPfam hit to PF03466, LysR substrate binding domain, score 8e-36 291112013460 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112013461 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112013462 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 291112013463 putative effector binding pocket; other site 291112013464 dimerization interface [polypeptide binding]; other site 291112013465 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.4e-44 291112013466 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.1e-13 291112013467 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 291112013468 Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531 291112013469 DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025 291112013470 catalytic residues [active] 291112013471 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989 291112013472 Type IV leader peptidase family; Region: Peptidase_A24; pfam01478 291112013473 7 probable transmembrane helices predicted for PAT0077 by TMHMM2.0 at aa 7-29, 39-61, 66-83, 93-112, 117-139, 159-181 and 194-211 291112013474 HMMPfam hit to PF01478, Type IV leader peptidase family, score 1.1e-22 291112013475 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385 291112013476 RNA methyltransferase, RsmE family; Region: TIGR00046 291112013477 1 probable transmembrane helix predicted for PAT0078 by TMHMM2.0 at aa 4-21 291112013478 HMMPfam hit to PF04452, Protein of unknown function (DUF558), score 5.7e-102 291112013479 glutathione synthetase; Provisional; Region: PRK05246 291112013480 Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951 291112013481 Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955 291112013482 HMMPfam hit to PF02951, Prokaryotic glutathione synthetase, N-ter, score 1e-70 291112013483 HMMPfam hit to PF08443, RimK-like ATP-grasp domain, score 0.0036 291112013484 HMMPfam hit to PF02655, ATP-grasp domain, score 0.0014 291112013485 HMMPfam hit to PF02955, Prokaryotic glutathione synthetase, ATP-g, score 1.4e-125 291112013486 hypothetical protein; Validated; Region: PRK00228 291112013487 HMMPfam hit to PF02622, Uncharacterized ACR, COG1678, score 3.2e-97 291112013488 Holliday junction resolvase-like protein; Reviewed; Region: PRK00109 291112013489 HMMPfam hit to PF03652, Uncharacterised protein family (UPF0081), score 1.5e-63 291112013490 HMMSmart hit to SM00732, no description, score 9.7e-41 291112013491 Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805 291112013492 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 291112013493 Walker A motif; other site 291112013494 ATP binding site [chemical binding]; other site 291112013495 Walker B motif; other site 291112013496 HMMPfam hit to PF00437, Type II/IV secretion system protein, score 4.1e-27 291112013497 Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824 291112013498 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 291112013499 catalytic residue [active] 291112013500 HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 2.1e-33 291112013501 pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880 291112013502 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232 291112013503 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 3.9e-05 291112013504 HMMPfam hit to PF03807, NADP oxidoreductase coenzyme F420-depe, score 8.8e-61 291112013505 YGGT family; Region: YGGT; pfam02325 291112013506 YGGT family; Region: YGGT; pfam02325 291112013507 HMMPfam hit to PF02325, YGGT family, score 1.9e-21 291112013508 4 probable transmembrane helices predicted for PAT0085 by TMHMM2.0 at aa 3-25, 53-75, 82-104 and 148-170 291112013509 HMMPfam hit to PF02325, YGGT family, score 4.3e-23 291112013510 NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515 291112013511 active site 291112013512 dimerization interface [polypeptide binding]; other site 291112013513 HMMPfam hit to PF01725, Ham1 family, score 2.1e-102 291112013514 HemN family oxidoreductase; Provisional; Region: PRK05660 291112013515 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112013516 FeS/SAM binding site; other site 291112013517 HemN C-terminal domain; Region: HemN_C; pfam06969 291112013518 HMMSmart hit to SM00729, no description, score 8.6e-50 291112013519 HMMPfam hit to PF04055, Radical SAM superfamily, score 3.8e-24 291112013520 HMMPfam hit to PF06969, HemN C-terminal region, score 3.6e-21 291112013521 ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607 291112013522 Siderophore binding protein FatB. These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species. They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140 291112013523 putative ligand binding residues [chemical binding]; other site 291112013524 HMMPfam hit to PF01497, Periplasmic binding protein, score 2.6e-37 291112013525 hypothetical protein; Provisional; Region: PRK10626 291112013526 Protein of unknown function (DUF2884); Region: DUF2884; pfam11101 291112013527 glutaminase; Provisional; Region: PRK00971 291112013528 Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066 291112013529 HMMPfam hit to PF04960, Glutaminase, score 9e-187 291112013530 hypothetical protein; Provisional; Region: PRK11702 291112013531 HMMPfam hit to PF04320, Protein with unknown function (DUF469), score 1.8e-70 291112013532 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112013533 S-adenosylmethionine binding site [chemical binding]; other site 291112013534 HMMPfam hit to PF02390, Putative methyltransferase, score 1.1e-93 291112013535 adenine DNA glycosylase; Provisional; Region: PRK10880 291112013536 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 291112013537 minor groove reading motif; other site 291112013538 helix-hairpin-helix signature motif; other site 291112013539 substrate binding pocket [chemical binding]; other site 291112013540 active site 291112013541 iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525 291112013542 DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431 291112013543 DNA binding and oxoG recognition site [nucleotide binding] 291112013544 HMMPfam hit to PF00730, HhH-GPD superfamily base excision DNA repair, score 5.1e-21 291112013545 HMMSmart hit to SM00478, no description, score 1.6e-49 291112013546 HMMPfam hit to PF00633, Helix-hairpin-helix motif, score 2.1e-05 291112013547 HMMSmart hit to SM00525, no description, score 2e-05 291112013548 oxidative damage protection protein; Provisional; Region: PRK05408 291112013549 HMMPfam hit to PF04362, Bacterial Fe(2+) trafficking, score 9.6e-61 291112013550 murein transglycosylase C; Provisional; Region: mltC; PRK11671 291112013551 Domain of unknown function (DUF3393); Region: DUF3393; pfam11873 291112013552 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 291112013553 N-acetyl-D-glucosamine binding site [chemical binding]; other site 291112013554 catalytic residue [active] 291112013555 HMMPfam hit to PF01464, Transglycosylase SLT domain, score 2.4e-47 291112013556 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112013557 DNA binding site [nucleotide binding] 291112013558 active site 291112013559 Int/Topo IB signature motif; other site 291112013560 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 291112013561 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 291112013562 DNA binding site [nucleotide binding] 291112013563 Protein of unknown function (DUF1281); Region: DUF1281; pfam06924 291112013564 HMMPfam hit to PF06924, Protein of unknown function (DUF1281), score 2.4e-24 291112013565 Protein of unknown function (DUF3085); Region: DUF3085; pfam11284 291112013566 Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227 291112013567 Domain of unknown function (DUF1738); Region: DUF1738; pfam08401 291112013568 Protein of unknown function (DUF1219); Region: DUF1219; pfam06755 291112013569 HMMPfam hit to PF06755, Protein of unknown function (DUF1219), score 0.00025 291112013570 1 probable transmembrane helix predicted for PAT0107 by TMHMM2.0 at aa 112-134 291112013571 1 probable transmembrane helix predicted for PAT0109 by TMHMM2.0 at aa 4-26 291112013572 1 probable transmembrane helix predicted for PAT0110 by TMHMM2.0 at aa 46-68 291112013573 Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834 291112013574 Integrase; Region: Integrase_1; pfam12835 291112013575 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 291112013576 haemagglutination activity domain; Region: Haemagg_act; pfam05860 291112013577 Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210 291112013578 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112013579 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112013580 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 291112013581 Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829 291112013582 CHC2 zinc finger; Region: zf-CHC2; cl17510 291112013583 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112013584 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112013585 active site 291112013586 metal binding site [ion binding]; metal-binding site 291112013587 interdomain interaction site; other site 291112013588 HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 4.6e-18 291112013589 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 3.7e-13 291112013590 HMMPfam hit to PF01751, TOPRIM, score 0.00027 291112013591 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287 291112013592 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 291112013593 active site 291112013594 Int/Topo IB signature motif; other site 291112013595 HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 6.6e-32 291112013596 CHC2 zinc finger; Region: zf-CHC2; cl17510 291112013597 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112013598 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112013599 active site 291112013600 metal binding site [ion binding]; metal-binding site 291112013601 interdomain interaction site; other site 291112013602 HMMPfam hit to PF01807, Zinc finger, CHC2-type, score 3.7e-22 291112013603 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 3.7e-13 291112013604 HMMPfam hit to PF01751, TOPRIM, score 0.00027 291112013605 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287 291112013606 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 291112013607 active site 291112013608 Int/Topo IB signature motif; other site 291112013609 HMMPfam hit to PF00589, Integrase, catalytic core, phage, score 6.6e-32 291112013610 2 probable transmembrane helices predicted for PAT0129 by TMHMM2.0 at aa 20-42 and 57-79 291112013611 2 probable transmembrane helices predicted for PAT0132 by TMHMM2.0 at aa 7-29 and 51-73 291112013612 Protein of unknown function (DUF4237); Region: DUF4237; pfam14021 291112013613 Protein of unknown function (DUF3916); Region: DUF3916; pfam13079 291112013614 Transposase; Region: HTH_Tnp_1; cl17663 291112013615 Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007 291112013616 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 291112013617 putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005 291112013618 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 291112013619 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 291112013620 HMMPfam hit to PF03050, Transposase IS66 family, score 3.7e-09 291112013621 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 291112013622 IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817 291112013623 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189 291112013624 HMMPfam hit to PF01695, IstB-like ATP binding protein, score 4.1e-07 291112013625 Bacteriophage lysis protein; Region: Phage_lysis; pfam03245 291112013626 HMMPfam hit to PF03245, Bacteriophage lysis protein, score 7.4e-29 291112013627 Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737 291112013628 catalytic residues [active] 291112013629 HMMPfam hit to PF00959, Phage lysozyme, score 1.6e-34 291112013630 1 probable transmembrane helix predicted for PAT0147 by TMHMM2.0 at aa 21-43 291112013631 Rho-activating domain of cytotoxic necrotizing factor; Region: CNF1; pfam05785 291112013632 HMMPfam hit to PF05785, Rho-activating domain of cytotoxic necrotizi, score 6.1e-19 291112013633 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112013634 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112013635 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix protei, score 7.7e-13 291112013636 Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826 291112013637 1 probable transmembrane helix predicted for PAT0153 by TMHMM2.0 at aa 17-39 291112013638 Protein of unknown function (DUF4255); Region: DUF4255; pfam14065 291112013639 ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464 291112013640 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112013641 Walker A motif; other site 291112013642 ATP binding site [chemical binding]; other site 291112013643 Walker B motif; other site 291112013644 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 1.9e-35 291112013645 HMMSmart hit to SM00382, no description, score 4.4e-11 291112013646 Phage Tail Collar Domain; Region: Collar; pfam07484 291112013647 HMMPfam hit to PF07484, Phage Tail Collar Domain, score 6.1e-14 291112013648 HMMPfam hit to PF00608, Adenoviral fibre protein (repeat/shaft re, score 0.29 291112013649 HMMPfam hit to PF00608, Adenoviral fibre protein (repeat/shaft re, score 0.3 291112013650 Gene 25-like lysozyme; Region: GPW_gp25; pfam04965 291112013651 HMMPfam hit to PF04965, GPW / gp25 family, score 2.4e-24 291112013652 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 291112013653 Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796 291112013654 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112013655 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841 291112013656 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112013657 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112013658 Phage tail sheath protein FI [General function prediction only]; Region: COG3497 291112013659 T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841 291112013660 2 probable transmembrane helices predicted for PAT0173 by TMHMM2.0 at aa 12-31 and 70-92 291112013661 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539 291112013662 Condensation domain; Region: Condensation; pfam00668 291112013663 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112013664 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112013665 acyl-activating enzyme (AAE) consensus motif; other site 291112013666 AMP binding site [chemical binding]; other site 291112013667 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112013668 Condensation domain; Region: Condensation; pfam00668 291112013669 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112013670 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112013671 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112013672 acyl-activating enzyme (AAE) consensus motif; other site 291112013673 AMP binding site [chemical binding]; other site 291112013674 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112013675 Condensation domain; Region: Condensation; pfam00668 291112013676 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112013677 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112013678 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112013679 acyl-activating enzyme (AAE) consensus motif; other site 291112013680 AMP binding site [chemical binding]; other site 291112013681 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112013682 Condensation domain; Region: Condensation; pfam00668 291112013683 non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261 291112013684 HMMPfam hit to PF00668, Condensation domain, score 5.4e-16 291112013685 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.3e-161 291112013686 HMMPfam hit to PF00501, AMP-binding enzyme, score 4.7e-159 291112013687 HMMPfam hit to PF00501, AMP-binding enzyme, score 9.7e-153 291112013688 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 1.9e-20 291112013689 HMMPfam hit to PF00668, Condensation domain, score 2.5e-63 291112013690 Condensation domain; Region: Condensation; pfam00668 291112013691 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112013692 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 291112013693 acyl-activating enzyme (AAE) consensus motif; other site 291112013694 AMP binding site [chemical binding]; other site 291112013695 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112013696 Condensation domain; Region: Condensation; pfam00668 291112013697 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112013698 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 291112013699 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 291112013700 acyl-activating enzyme (AAE) consensus motif; other site 291112013701 AMP binding site [chemical binding]; other site 291112013702 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112013703 HMMPfam hit to PF00668, Condensation domain, score 6.8e-45 291112013704 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.8e-154 291112013705 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.2e-152 291112013706 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.2e-19 291112013707 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112013708 DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930 291112013709 Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436 291112013710 Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796 291112013711 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112013712 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318 291112013713 acyl-activating enzyme (AAE) consensus motif; other site 291112013714 AMP binding site [chemical binding]; other site 291112013715 active site 291112013716 CoA binding site [chemical binding]; other site 291112013717 HMMPfam hit to PF00501, AMP-binding enzyme, score 1.6e-81 291112013718 TcdA/TcdB pore forming domain; Region: TcdA_TcdB_pore; pfam12920 291112013719 Flavoprotein; Region: Flavoprotein; pfam02441 291112013720 HMMPfam hit to PF02441, Flavoprotein, score 1.4e-19 291112013721 Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454 291112013722 apolar tunnel; other site 291112013723 heme binding site [chemical binding]; other site 291112013724 dimerization interface [polypeptide binding]; other site 291112013725 HMMPfam hit to PF01152, Bacterial-like globin, score 0.00018 291112013726 Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508 291112013727 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.1e-08 291112013728 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 291112013729 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 291112013730 active site 291112013731 HMMPfam hit to PF00732, GMC oxidoreductase, score 6.8e-47 291112013732 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 291112013733 Nonribosomal peptide synthase; Region: NRPS; pfam08415 291112013734 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114 291112013735 acyl-activating enzyme (AAE) consensus motif; other site 291112013736 AMP binding site [chemical binding]; other site 291112013737 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 291112013738 HMMPfam hit to PF00550, Phosphopantetheine attachment site, score 2.8e-07 291112013739 HMMPfam hit to PF00501, AMP-binding enzyme, score 2.2e-126 291112013740 HMMPfam hit to PF08415, Nonribosomal peptide synthase, score 1e-14 291112013741 Condensation domain; Region: Condensation; pfam00668 291112013742 2 probable transmembrane helices predicted for PAT0196 by TMHMM2.0 at aa 7-29 and 39-61 291112013743 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112013744 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 291112013745 putative substrate translocation pore; other site 291112013746 14 probable transmembrane helices predicted for PAT0197 by TMHMM2.0 at aa 41-63, 73-95, 108-130, 134-153, 166-188, 193-212, 232-251, 256-278, 298-320, 330-352, 359-381, 391-413, 426-448 and 458-480 291112013747 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.8e-39 291112013748 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 291112013749 dimerization interface [polypeptide binding]; other site 291112013750 putative DNA binding site [nucleotide binding]; other site 291112013751 putative Zn2+ binding site [ion binding]; other site 291112013752 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 291112013753 active site residue [active] 291112013754 HMMSmart hit to SM00450, no description, score 1e-24 291112013755 HMMPfam hit to PF00581, Rhodanese-like domain, score 8.7e-13 291112013756 HMMSmart hit to SM00418, no description, score 2.1e-18 291112013757 Protein of unknown function (DUF2938); Region: DUF2938; pfam11158 291112013758 3 probable transmembrane helices predicted for PAT0199 by TMHMM2.0 at aa 22-44, 59-81 and 94-116 291112013759 inosine/guanosine kinase; Provisional; Region: PRK15074 291112013760 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 291112013761 substrate binding site [chemical binding]; other site 291112013762 ATP binding site [chemical binding]; other site 291112013763 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 8.2e-24 291112013764 LPS O-antigen length regulator; Provisional; Region: PRK10381 291112013765 Chain length determinant protein; Region: Wzz; pfam02706 291112013766 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 291112013767 2 probable transmembrane helices predicted for PAT0202 by TMHMM2.0 at aa 41-63 and 338-357 291112013768 HMMPfam hit to PF02706, Chain length determinant protein, score 1.9e-16 291112013769 ferrochelatase; Reviewed; Region: hemH; PRK00035 291112013770 Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411 291112013771 C-terminal domain interface [polypeptide binding]; other site 291112013772 active site 291112013773 Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419 291112013774 active site 291112013775 N-terminal domain interface [polypeptide binding]; other site 291112013776 HMMPfam hit to PF00762, Ferrochelatase, score 6.7e-124 291112013777 adenylate kinase; Reviewed; Region: adk; PRK00279 291112013778 Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428 291112013779 AMP-binding site [chemical binding]; other site 291112013780 ATP-AMP (Ap5A)-binding site [chemical binding]; other site 291112013781 HMMPfam hit to PF00406, Adenylate kinase, score 2.5e-94 291112013782 HMMPfam hit to PF05191, Adenylate kinase, active site lid, score 3.5e-18 291112013783 heat shock protein 90; Provisional; Region: PRK05218 291112013784 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112013785 ATP binding site [chemical binding]; other site 291112013786 Mg2+ binding site [ion binding]; other site 291112013787 G-X-G motif; other site 291112013788 HMMPfam hit to PF00183, Hsp90 protein, score 1.7e-92 291112013789 HMMSmart hit to SM00387, no description, score 6.3e-12 291112013790 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 5.7e-17 291112013791 recombination protein RecR; Reviewed; Region: recR; PRK00076 291112013792 RecR protein; Region: RecR; pfam02132 291112013793 TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR. RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025 291112013794 putative active site [active] 291112013795 putative metal-binding site [ion binding]; other site 291112013796 tetramer interface [polypeptide binding]; other site 291112013797 HMMPfam hit to PF01751, Toprim domain, score 3.4e-19 291112013798 HMMSmart hit to SM00493, no description, score 2.1e-16 291112013799 HMMPfam hit to PF02132, RecR protein, score 4.9e-18 291112013800 hypothetical protein; Validated; Region: PRK00153 291112013801 HMMPfam hit to PF02575, Uncharacterised BCR, YbaB family COG0718, score 4.4e-53 291112013802 DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994 291112013803 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112013804 Walker A motif; other site 291112013805 ATP binding site [chemical binding]; other site 291112013806 Walker B motif; other site 291112013807 arginine finger; other site 291112013808 DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169 291112013809 DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168 291112013810 DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170 291112013811 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 3.2e-08 291112013812 HMMSmart hit to SM00382, no description, score 3.5e-07 291112013813 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112013814 active site 291112013815 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 5e-49 291112013816 1 probable transmembrane helix predicted for PAT0210 by TMHMM2.0 at aa 5-27 291112013817 Primosomal replication protein priB and priC; Region: priB_priC; pfam07445 291112013818 HMMPfam hit to PF07445, Primosomal replication protein priB and pri, score 2.1e-65 291112013819 hypothetical protein; Provisional; Region: PRK11038 291112013820 Protein of unknown function (DUF1284); Region: DUF1284; cl01419 291112013821 HMMPfam hit to PF06935, Protein of unknown function (DUF1284), score 8.7e-43 291112013822 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; cl17304 291112013823 BioY family; Region: BioY; pfam02632 291112013824 HMMPfam hit to PF02632, BioY family, score 5.2e-24 291112013825 5 probable transmembrane helices predicted for PAT0215 by TMHMM2.0 at aa 10-32, 53-75, 81-103, 116-138 and 148-167 291112013826 ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619 291112013827 HMMPfam hit to PF02361, Cobalt transport protein, score 1.9e-14 291112013828 3 probable transmembrane helices predicted for PAT0216 by TMHMM2.0 at aa 13-35, 40-59 and 72-94 291112013829 ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122 291112013830 First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225 291112013831 Walker A/P-loop; other site 291112013832 ATP binding site [chemical binding]; other site 291112013833 Q-loop/lid; other site 291112013834 ABC transporter signature motif; other site 291112013835 Walker B; other site 291112013836 D-loop; other site 291112013837 H-loop/switch region; other site 291112013838 HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 9.1e-06 291112013839 HMMSmart hit to SM00382, no description, score 7.5e-14 291112013840 HMMPfam hit to PF00005, ABC transporter, score 2.4e-48 291112013841 DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668 291112013842 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112013843 MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361 291112013844 HMMPfam hit to PF08361, MAATS-type transcriptional repressor, C-term, score 7.8e-81 291112013845 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 7.6e-21 291112013846 multidrug efflux system transporter AcrA; Provisional; Region: PRK15030 291112013847 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112013848 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112013849 HMMPfam hit to PF00529, HlyD family secretion protein, score 4.5e-82 291112013850 multidrug efflux system protein AcrB; Provisional; Region: PRK15127 291112013851 Protein export membrane protein; Region: SecD_SecF; cl14618 291112013852 HMMPfam hit to PF00873, AcrB/AcrD/AcrF family, score 0 291112013853 11 probable transmembrane helices predicted for PAT0220 by TMHMM2.0 at aa 10-27, 340-359, 369-391, 438-460, 470-492, 540-559, 875-894, 901-923, 928-950, 977-999 and 1009-1031 291112013854 Biofilm formation regulator YbaJ; Region: YbaJ; cl11675 291112013855 gene expression modulator; Provisional; Region: PRK10945 291112013856 HMMPfam hit to PF05321, Haemolysin expression modulating protein, score 1.5e-35 291112013857 Type III secretion system lipoprotein chaperone (YscW); Region: YscW; cl15825 291112013858 acyl-CoA thioesterase II; Provisional; Region: PRK10526 291112013859 Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445 291112013860 active site 291112013861 Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444 291112013862 catalytic triad [active] 291112013863 dimer interface [polypeptide binding]; other site 291112013864 HMMPfam hit to PF02551, Acyl-CoA thioesterase, score 2.6e-37 291112013865 HMMPfam hit to PF02551, Acyl-CoA thioesterase, score 8.5e-52 291112013866 ammonium transporter; Provisional; Region: PRK10666 291112013867 HMMPfam hit to PF00909, Ammonium Transporter Family, score 6.4e-168 291112013868 12 probable transmembrane helices predicted for PAT0225 by TMHMM2.0 at aa 5-23, 33-55, 62-84, 120-142, 149-171, 186-205, 218-237, 252-274, 279-298, 302-324, 337-359 and 374-396 291112013869 nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665 291112013870 Nitrogen regulatory protein P-II; Region: P-II; smart00938 291112013871 HMMPfam hit to PF00543, Nitrogen regulatory protein P-II, score 2.5e-64 291112013872 1 probable transmembrane helix predicted for PAT0227 by TMHMM2.0 at aa 10-32 291112013873 putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790 291112013874 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112013875 ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254 291112013876 Walker A/P-loop; other site 291112013877 ATP binding site [chemical binding]; other site 291112013878 Q-loop/lid; other site 291112013879 ABC transporter signature motif; other site 291112013880 Walker B; other site 291112013881 D-loop; other site 291112013882 H-loop/switch region; other site 291112013883 HMMSmart hit to SM00382, no description, score 3.9e-14 291112013884 HMMPfam hit to PF00005, ABC transporter, score 3.2e-50 291112013885 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 4.8e-34 291112013886 5 probable transmembrane helices predicted for PAT0228 by TMHMM2.0 at aa 25-47, 62-84, 140-162, 167-189 and 249-271 291112013887 putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789 291112013888 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 291112013889 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112013890 Walker A/P-loop; other site 291112013891 ATP binding site [chemical binding]; other site 291112013892 Q-loop/lid; other site 291112013893 ABC transporter signature motif; other site 291112013894 Walker B; other site 291112013895 D-loop; other site 291112013896 H-loop/switch region; other site 291112013897 HMMSmart hit to SM00382, no description, score 7.8e-14 291112013898 HMMPfam hit to PF00005, ABC transporter, score 2e-54 291112013899 6 probable transmembrane helices predicted for PAT0229 by TMHMM2.0 at aa 21-43, 58-77, 129-151, 156-175, 246-268 and 278-300 291112013900 HMMPfam hit to PF00664, ABC transporter transmembrane region, score 6.9e-29 291112013901 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 291112013902 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 291112013903 putative DNA binding site [nucleotide binding]; other site 291112013904 putative Zn2+ binding site [ion binding]; other site 291112013905 AsnC family; Region: AsnC_trans_reg; pfam01037 291112013906 HMMPfam hit to PF01037, AsnC family, score 3e-24 291112013907 HMMSmart hit to SM00344, no description, score 2e-40 291112013908 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 291112013909 Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342 291112013910 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112013911 catalytic residue [active] 291112013912 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 1.1e-53 291112013913 ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995 291112013914 Ligand Binding Site [chemical binding]; other site 291112013915 HMMPfam hit to PF06508, ExsB, score 1.1e-104 291112013916 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 291112013917 active site 291112013918 HMMPfam hit to PF03061, Thioesterase superfamily, score 4.3e-19 291112013919 competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426 291112013920 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786 291112013921 HMMSmart hit to SM00278, no description, score 1.4e+02 291112013922 HMMSmart hit to SM00278, no description, score 5 291112013923 1 probable transmembrane helix predicted for PAT0234 by TMHMM2.0 at aa 7-26 291112013924 periplasmic folding chaperone; Provisional; Region: PRK10788 291112013925 SurA N-terminal domain; Region: SurA_N_3; cl07813 291112013926 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 291112013927 HMMPfam hit to PF00639, PPIC-type PPIASE domain, score 2.8e-13 291112013928 1 probable transmembrane helix predicted for PAT0235 by TMHMM2.0 at aa 13-35 291112013929 Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591 291112013930 IHF dimer interface [polypeptide binding]; other site 291112013931 IHF - DNA interface [nucleotide binding]; other site 291112013932 HMMPfam hit to PF00216, Bacterial DNA-binding protein, score 1e-48; HMMSmart hit to SM00411, no description, score 1.7e-43 291112013933 DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787 291112013934 Found in ATP-dependent protease La (LON); Region: LON; smart00464 291112013935 Found in ATP-dependent protease La (LON); Region: LON; smart00464 291112013936 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112013937 Walker A motif; other site 291112013938 ATP binding site [chemical binding]; other site 291112013939 Walker B motif; other site 291112013940 arginine finger; other site 291112013941 Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362 291112013942 HMMPfam hit to PF05362, Lon protease (S16) C-terminal proteolytic do, score 3.5e-152 291112013943 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 3.9e-44 291112013944 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 1e-05 291112013945 HMMSmart hit to SM00382, no description, score 2e-11 291112013946 HMMPfam hit to PF02190, ATP-dependent protease La (LON) domain, score 6.2e-72; HMMSmart hit to SM00464, no description, score 1.1e-82 291112013947 ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342 291112013948 ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689 291112013949 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112013950 Walker A motif; other site 291112013951 ATP binding site [chemical binding]; other site 291112013952 Walker B motif; other site 291112013953 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 291112013954 HMMPfam hit to PF00004, ATPase family associated with various cell, score 2.1e-05 291112013955 HMMSmart hit to SM00382, no description, score 5.3e-10 291112013956 HMMPfam hit to PF07724, ATPase family associated with various cell, score 3.2e-80 291112013957 HMMPfam hit to PF06689, ClpX C4-type zinc finger, score 4.9e-27 291112013958 Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740 291112013959 Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017 291112013960 oligomer interface [polypeptide binding]; other site 291112013961 active site residues [active] 291112013962 HMMPfam hit to PF00574, Clp protease, score 1.2e-138 291112013963 Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917 291112013964 1 probable transmembrane helix predicted for PAT0242 by TMHMM2.0 at aa 5-27 291112013965 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 291112013966 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 291112013967 putative active site [active] 291112013968 HMMPfam hit to PF01075, Glycosyltransferase family 9 (heptosyl, score 4.5e-05 291112013969 trigger factor; Provisional; Region: tig; PRK01490 291112013970 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 291112013971 Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698 291112013972 HMMPfam hit to PF05698, Bacterial trigger factor protein (TF) C-ter, score 1.1e-56 291112013973 HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomera, score 8.3e-28 291112013974 HMMPfam hit to PF05697, Bacterial trigger factor protein (TF), score 2.4e-74 291112013975 transcriptional regulator BolA; Provisional; Region: PRK11628 291112013976 HMMPfam hit to PF01722, BolA-like protein, score 3e-34 291112013977 hypothetical protein; Provisional; Region: PRK11627 291112013978 Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923 291112013979 HMMPfam hit to PF03923, Uncharacterized lipoprotein, score 3.1e-06 291112013980 1 probable transmembrane helix predicted for PAT0246 by TMHMM2.0 at aa 5-27 291112013981 muropeptide transporter; Reviewed; Region: ampG; PRK11902 291112013982 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112013983 putative substrate translocation pore; other site 291112013984 14 probable transmembrane helices predicted for PAT0247 by TMHMM2.0 at aa 16-38, 48-69, 82-101, 106-123, 144-166, 170-192, 228-250, 260-282, 287-309, 319-341, 354-376, 380-402, 423-445 and 465-487 291112013985 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1e-27 291112013986 hypothetical protein; Provisional; Region: PRK11528 291112013987 HMMPfam hit to PF07135, Protein of unknown function (DUF1384), score 2.3e-161 291112013988 cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525 291112013989 Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116 291112013990 COX Aromatic Rich Motif; Region: COX_ARM; pfam06481 291112013991 3 probable transmembrane helices predicted for PAT0249 by TMHMM2.0 at aa 12-30, 45-67 and 88-108 291112013992 HMMPfam hit to PF00116, Cytochrome C oxidase subunit II, periplasmic, score 1.1e-06 291112013993 HMMPfam hit to PF06481, COX Aromatic Rich Motif, score 4.8e-20 291112013994 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 291112013995 Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662 291112013996 D-pathway; other site 291112013997 Putative ubiquinol binding site [chemical binding]; other site 291112013998 Low-spin heme (heme b) binding site [chemical binding]; other site 291112013999 Putative water exit pathway; other site 291112014000 Binuclear center (heme o3/CuB) [ion binding]; other site 291112014001 K-pathway; other site 291112014002 Putative proton exit pathway; other site 291112014003 14 probable transmembrane helices predicted for PAT0250 by TMHMM2.0 at aa 15-37, 57-79, 105-127, 140-162, 191-213, 233-255, 275-297, 310-332, 347-369, 381-403, 418-440, 457-479, 494-516 and 590-612 291112014004 HMMPfam hit to PF00115, Cytochrome C and Quinol oxidase polypeptide, score 1e-251 291112014005 Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863 291112014006 Subunit I/III interface [polypeptide binding]; other site 291112014007 Subunit III/IV interface [polypeptide binding]; other site 291112014008 HMMPfam hit to PF00510, Cytochrome c oxidase subunit III, score 5.4e-06 291112014009 5 probable transmembrane helices predicted for PAT0251 by TMHMM2.0 at aa 28-50, 65-87, 100-119, 139-161 and 182-204 291112014010 cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582 291112014011 3 probable transmembrane helices predicted for PAT0252 by TMHMM2.0 at aa 13-35, 45-67 and 79-101 291112014012 HMMPfam hit to PF03626, Prokaryotic Cytochrome C oxidase subunit IV, score 3.9e-50 291112014013 protoheme IX farnesyltransferase; Provisional; Region: PRK13362 291112014014 UbiA prenyltransferase family; Region: UbiA; pfam01040 291112014015 9 probable transmembrane helices predicted for PAT0253 by TMHMM2.0 at aa 13-32, 37-59, 79-101, 106-125, 132-154, 159-181, 208-230, 234-251 and 263-280 291112014016 HMMPfam hit to PF01040, UbiA prenyltransferase family, score 4.4e-78 291112014017 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112014018 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112014019 putative substrate translocation pore; other site 291112014020 HMMPfam hit to PF00083, Sugar (and other) transporter, score 0.00016 291112014021 12 probable transmembrane helices predicted for PAT0254 by TMHMM2.0 at aa 13-35, 50-72, 79-98, 102-124, 137-159, 164-186, 217-239, 249-271, 280-302, 306-328, 340-362 and 366-385 291112014022 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.4e-50 291112014023 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666 291112014024 Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740 291112014025 HMMPfam hit to PF04461, Protein of unknown function (DUF520), score 1e-109 291112014026 2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522 291112014027 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 291112014028 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 291112014029 HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 1.1e-40 291112014030 HMMPfam hit to PF08546, Ketopantoate reductase PanE/ApbA C terminal, score 2.8e-55 291112014031 oxidative-stress-resistance chaperone; Provisional; Region: PRK11574 291112014032 Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135 291112014033 conserved cys residue [active] 291112014034 HMMPfam hit to PF01965, DJ-1/PfpI family, score 1e-33 291112014035 tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269 291112014036 THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716 291112014037 ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712 291112014038 Ligand Binding Site [chemical binding]; other site 291112014039 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 291112014040 active site residue [active] 291112014041 HMMPfam hit to PF02568, Thiamine biosynthesis protein (ThiI), score 5.3e-107 291112014042 HMMPfam hit to PF06508, ExsB, score 0.0016 291112014043 HMMPfam hit to PF02926, THUMP domain, score 2.4e-24 291112014044 exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977 291112014045 HMMPfam hit to PF02609, Exonuclease VII small subunit, score 1.4e-29 291112014046 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142 291112014047 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 291112014048 substrate binding pocket [chemical binding]; other site 291112014049 chain length determination region; other site 291112014050 substrate-Mg2+ binding site; other site 291112014051 catalytic residues [active] 291112014052 aspartate-rich region 1; other site 291112014053 active site lid residues [active] 291112014054 aspartate-rich region 2; other site 291112014055 HMMPfam hit to PF00348, Polyprenyl synthetase, score 2.4e-114 291112014056 1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444 291112014057 Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007 291112014058 TPP-binding site; other site 291112014059 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 291112014060 PYR/PP interface [polypeptide binding]; other site 291112014061 dimer interface [polypeptide binding]; other site 291112014062 TPP binding site [chemical binding]; other site 291112014063 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 291112014064 HMMPfam hit to PF02779, Transketolase, pyridine binding domai, score 3.5e-62 291112014065 HMMPfam hit to PF02780, Transketolase, C-terminal domain, score 3.7e-41 291112014066 1 probable transmembrane helix predicted for PAT0263 by TMHMM2.0 at aa 5-22 291112014067 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355 291112014068 DNA binding site [nucleotide binding] 291112014069 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 291112014070 1 probable transmembrane helix predicted for PAT0264 by TMHMM2.0 at aa 188-210 291112014071 HMMPfam hit to PF00486, Transcriptional regulatory protein, C ter, score 8.6e-07 291112014072 Initiator Replication protein; Region: Rep_3; pfam01051 291112014073 Surface presentation of antigens (SPOA); Region: SpoA; cl00819 291112014074 1 probable transmembrane helix predicted for PAT0269 by TMHMM2.0 at aa 102-124 291112014075 SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; Region: SERPIN; cl00137 291112014076 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 291112014077 ligand binding site [chemical binding]; other site 291112014078 HMMPfam hit to PF00691, OmpA family, score 0.00032 291112014079 type III secretion protein, YscU/HrpY family; Region: FlhB_rel_III; TIGR01404 291112014080 HMMPfam hit to PF01312, FlhB HrpN YscU SpaS Family, score 2e-29 291112014081 4 probable transmembrane helices predicted for PAT0272 by TMHMM2.0 at aa 36-58, 78-100, 139-158 and 178-200 291112014082 FHIPEP family; Region: FHIPEP; pfam00771 291112014083 Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980 291112014084 Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980 291112014085 HMMPfam hit to PF00771, FHIPEP family, score 7.4e-69 291112014086 8 probable transmembrane helices predicted for PAT0273 by TMHMM2.0 at aa 7-29, 33-55, 68-90, 105-127, 196-218, 233-255, 276-295 and 299-318 291112014087 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 291112014088 Inner membrane complex protein; Region: IMCp; pfam12314 291112014089 1 probable transmembrane helix predicted for PAT0275 by TMHMM2.0 at aa 102-124 291112014090 1 probable transmembrane helix predicted for PAT0281 by TMHMM2.0 at aa 116-138 291112014091 type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552 291112014092 Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907 291112014093 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 291112014094 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112014095 DNA binding site [nucleotide binding] 291112014096 1 probable transmembrane helix predicted for PAT0288 by TMHMM2.0 at aa 153-175 291112014097 HMMPfam hit to PF00486, Transcriptional regulatory protein, C ter, score 8.8e-14 291112014098 1 probable transmembrane helix predicted for PAT0290 by TMHMM2.0 at aa 17-39 291112014099 Flagellar biosynthesis/type III secretory pathway ATPase [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliI; COG1157 291112014100 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 291112014101 Walker A motif; other site 291112014102 ATP binding site [chemical binding]; other site 291112014103 Walker B motif; other site 291112014104 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleotid, score 1.4e-79 291112014105 HMMSmart hit to SM00382, no description, score 4.5e-06 291112014106 type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516 291112014107 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 291112014108 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 291112014109 HMMPfam hit to PF03958, Bacterial type II/III secretion system sho, score 8.6e-08 291112014110 1 probable transmembrane helix predicted for PAT0294 by TMHMM2.0 at aa 5-24 291112014111 5 probable transmembrane helices predicted for PAT0296 by TMHMM2.0 at aa 5-22, 29-48, 58-80, 166-188 and 193-215 291112014112 type III secretion system protein YscR; Provisional; Region: PRK12797 291112014113 HMMPfam hit to PF00813, FliP family, score 2.6e-12 291112014114 3 probable transmembrane helices predicted for PAT0297 by TMHMM2.0 at aa 15-37, 185-207 and 212-234 291112014115 Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196 291112014116 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 291112014117 Beta-lactamase; Region: Beta-lactamase; pfam00144 291112014118 HMMPfam hit to PF00144, Beta-lactamase, score 2.4e-10 291112014119 1 probable transmembrane helix predicted for PAT0304 by TMHMM2.0 at aa 7-29 291112014120 Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971 291112014121 tetramer interfaces [polypeptide binding]; other site 291112014122 binuclear metal-binding site [ion binding]; other site 291112014123 4 probable transmembrane helices predicted for PAT0306 by TMHMM2.0 at aa 13-35, 45-67, 88-107 and 142-161 291112014124 HMMPfam hit to PF04608, Phosphatidylglycerophosphatase A, score 4.9e-79 291112014125 thiamine monophosphate kinase; Provisional; Region: PRK05731 291112014126 ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194 291112014127 ATP binding site [chemical binding]; other site 291112014128 dimerization interface [polypeptide binding]; other site 291112014129 HMMPfam hit to PF02769, AIR synthase related protein, C-terminal dom, score 9.8e-05 291112014130 Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619 291112014131 putative RNA binding site [nucleotide binding]; other site 291112014132 HMMPfam hit to PF01029, NusB family, score 3.2e-43 291112014133 lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209 291112014134 homopentamer interface [polypeptide binding]; other site 291112014135 active site 291112014136 HMMPfam hit to PF00885, 6,7-dimethyl-8-ribityllumazine synthase, score 3.1e-82 291112014137 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786 291112014138 Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284 291112014139 catalytic motif [active] 291112014140 Zn binding site [ion binding]; other site 291112014141 RibD C-terminal domain; Region: RibD_C; cl17279 291112014142 HMMPfam hit to PF01872, RibD C-terminal domain, score 1.9e-66 291112014143 HMMPfam hit to PF00383, Cytidine and deoxycytidylate deaminas, score 1.4e-36 291112014144 transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464 291112014145 ATP cone domain; Region: ATP-cone; pfam03477 291112014146 HMMPfam hit to PF03477, ATP cone domain, score 8.4e-34 291112014147 preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022 291112014148 SecD/SecF GG Motif; Region: Sec_GG; pfam07549 291112014149 Protein export membrane protein; Region: SecD_SecF; pfam02355 291112014150 HMMPfam hit to PF02355, Protein export membrane protein, score 2.5e-99 291112014151 6 probable transmembrane helices predicted for PAT0313 by TMHMM2.0 at aa 24-46, 139-161, 168-190, 194-216, 247-269 and 274-296 291112014152 HMMPfam hit to PF07549, SecD/SecF GG Motif, score 1.7e-06 291112014153 SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721 291112014154 preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812 291112014155 SecD/SecF GG Motif; Region: Sec_GG; pfam07549 291112014156 protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916 291112014157 HMMPfam hit to PF02355, Protein export membrane protein, score 5.6e-07 291112014158 6 probable transmembrane helices predicted for PAT0314 by TMHMM2.0 at aa 7-29, 452-470, 475-497, 502-524, 548-570 and 580-602 291112014159 HMMPfam hit to PF07549, SecD/SecF GG Motif, score 8.3e-06 291112014160 preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585 291112014161 HMMPfam hit to PF02699, Preprotein translocase subunit, score 1.9e-45 291112014162 1 probable transmembrane helix predicted for PAT0315 by TMHMM2.0 at aa 42-61 291112014163 queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112 291112014164 Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343 291112014165 HMMPfam hit to PF01702, Queuine tRNA-ribosyltransferase, score 1.2e-167 291112014166 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147 291112014167 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113 291112014168 HMMPfam hit to PF02547, Queuosine biosynthesis protein, score 1.5e-134 291112014169 Protein of unknown function, DUF479; Region: DUF479; cl01203 291112014170 HMMPfam hit to PF04336, Protein of unknown function, DUF479, score 2.8e-85 291112014171 peroxidase; Provisional; Region: PRK15000 291112014172 Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015 291112014173 dimer interface [polypeptide binding]; other site 291112014174 decamer (pentamer of dimers) interface [polypeptide binding]; other site 291112014175 catalytic triad [active] 291112014176 peroxidatic and resolving cysteines [active] 291112014177 HMMPfam hit to PF08534, Redoxin, score 5.5e-12 291112014178 HMMPfam hit to PF00578, AhpC/TSA family, score 9.6e-85 291112014179 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 291112014180 Transposase; Region: DEDD_Tnp_IS110; pfam01548 291112014181 HMMPfam hit to PF01548, Transposase, score 0.0017 291112014182 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 291112014183 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 291112014184 putative transposase OrfB; Reviewed; Region: PHA02517 291112014185 HTH-like domain; Region: HTH_21; pfam13276 291112014186 Integrase core domain; Region: rve; pfam00665 291112014187 Integrase core domain; Region: rve_2; pfam13333 291112014188 HMMPfam hit to PF00665, Integrase core domain, score 2.2e-42 291112014189 Homeodomain-like domain; Region: HTH_23; cl17451 291112014190 Helix-turn-helix domain; Region: HTH_28; pfam13518 291112014191 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 291112014192 Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019 291112014193 HMMPfam hit to PF01019, Gamma-glutamyltranspeptidase, score 3.4e-244 291112014194 Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547 291112014195 HMMPfam hit to PF05525, Branched-chain amino acid transport p, score 1.6e-217 291112014196 12 probable transmembrane helices predicted for PAT0326 by TMHMM2.0 at aa 13-35, 45-67, 80-102, 122-144, 156-178, 188-210, 223-245, 280-302, 315-337, 341-363, 370-387 and 410-427 291112014197 phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006 291112014198 Domain of unknown function (DUF3329); Region: DUF3329; pfam11808 291112014199 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 291112014200 putative active site [active] 291112014201 heme pocket [chemical binding]; other site 291112014202 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112014203 dimer interface [polypeptide binding]; other site 291112014204 phosphorylation site [posttranslational modification] 291112014205 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112014206 ATP binding site [chemical binding]; other site 291112014207 Mg2+ binding site [ion binding]; other site 291112014208 G-X-G motif; other site 291112014209 HMMSmart hit to SM00387, no description, score 3.2e-34 291112014210 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.2e-38 291112014211 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 4.4e-24; HMMSmart hit to SM00388, no description, score 2e-22 291112014212 HMMPfam hit to PF00989, PAS fold, score 2.2e-08 291112014213 HMMSmart hit to SM00091, no description, score 0.00011 291112014214 1 probable transmembrane helix predicted for PAT0327 by TMHMM2.0 at aa 21-43 291112014215 transcriptional regulator PhoB; Provisional; Region: PRK10161 291112014216 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112014217 active site 291112014218 phosphorylation site [posttranslational modification] 291112014219 intermolecular recognition site; other site 291112014220 dimerization interface [polypeptide binding]; other site 291112014221 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112014222 DNA binding site [nucleotide binding] 291112014223 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2e-23 291112014224 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.9e-37 291112014225 HMMSmart hit to SM00448, no description, score 3.1e-43 291112014226 exonuclease subunit SbcD; Provisional; Region: PRK10966 291112014227 Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840 291112014228 active site 291112014229 metal binding site [ion binding]; metal-binding site 291112014230 DNA binding site [nucleotide binding] 291112014231 Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320 291112014232 1 probable transmembrane helix predicted for PAT0329 by TMHMM2.0 at aa 13-32 291112014233 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 4.8e-17 291112014234 exonuclease SbcC; Region: sbcc; TIGR00618 291112014235 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112014236 Walker A/P-loop; other site 291112014237 ATP binding site [chemical binding]; other site 291112014238 Q-loop/lid; other site 291112014239 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112014240 ABC transporter signature motif; other site 291112014241 Walker B; other site 291112014242 D-loop; other site 291112014243 H-loop/switch region; other site 291112014244 HMMPfam hit to PF02463, RecF/RecN/SMC N terminal domain, score 4.3e-06 291112014245 HMMPfam hit to PF00904, no description, score 1.5e+02 291112014246 HMMPfam hit to PF00904, no description, score 3.7e+02 291112014247 HMMPfam hit to PF00904, no description, score 64 291112014248 HMMPfam hit to PF00904, no description, score 67 291112014249 HMMPfam hit to PF00904, no description, score 3.1e+02 291112014250 HMMPfam hit to PF00904, no description, score 84 291112014251 HMMPfam hit to PF00904, no description, score 62 291112014252 HMMPfam hit to PF00904, no description, score 50 291112014253 HMMPfam hit to PF00904, no description, score 20 291112014254 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737 291112014255 Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain; Region: MPP_YhcR_N; cd07412 291112014256 putative active site [active] 291112014257 putative metal binding site [ion binding]; other site 291112014258 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 291112014259 HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 3.8e-37 291112014260 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.4e-11 291112014261 Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases). Plant T2 RNases are expressed during leaf...; Region: RNase_T2; cl00208 291112014262 CAS motifs; other site 291112014263 active site 291112014264 HMMPfam hit to PF00445, Ribonuclease T2 family, score 8.8e-05 291112014265 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420 291112014266 Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410 291112014267 active site 291112014268 metal binding site [ion binding]; metal-binding site 291112014269 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 291112014270 HMMPfam hit to PF02872, 5'-nucleotidase, C-terminal domain, score 4.7e-58 291112014271 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 1.2e-17 291112014272 recombination associated protein; Reviewed; Region: rdgC; PRK00321 291112014273 HMMPfam hit to PF04381, Putative exonuclease, RdgC, score 7e-197 291112014274 Methyltransferase domain; Region: Methyltransf_31; pfam13847 291112014275 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112014276 S-adenosylmethionine binding site [chemical binding]; other site 291112014277 HMMPfam hit to PF05724, Thiopurine S-methyltransferase (TPMT), score 0.00063 291112014278 HMMPfam hit to PF08241, Methyltransferase domain, score 4.9e-10 291112014279 HMMPfam hit to PF08242, Methyltransferase domain, score 1.1e-12 291112014280 Fic family protein [Function unknown]; Region: COG3177 291112014281 Fic/DOC family; Region: Fic; pfam02661 291112014282 HMMPfam hit to PF02661, Fic protein family, score 6e-24 291112014283 Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229 291112014284 HMMPfam hit to PF01229, Glycosyl hydrolases family, score 0.0017 291112014285 biopolymer transport protein ExbD; Provisional; Region: PRK11267 291112014286 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 291112014287 HMMPfam hit to PF02472, Biopolymer transport protein ExbD/TolR, score 1e-24 291112014288 1 probable transmembrane helix predicted for PAT0340 by TMHMM2.0 at aa 20-42 291112014289 MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568 291112014290 HMMPfam hit to PF01618, MotA/TolQ/ExbB proton channel family, score 4.7e-51 291112014291 4 probable transmembrane helices predicted for PAT0341 by TMHMM2.0 at aa 66-88, 175-197, 285-307 and 331-353 291112014292 cystathionine beta-lyase; Provisional; Region: PRK08114 291112014293 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321 291112014294 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112014295 catalytic residue [active] 291112014296 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 3.3e-127 291112014297 putative regulator PrlF; Provisional; Region: PRK09974 291112014298 Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663 291112014299 Probable transposase; Region: OrfB_IS605; pfam01385 291112014300 Transposase IS200 like; Region: Y1_Tnp; cl00848 291112014301 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 291112014302 SNARE associated Golgi protein; Region: SNARE_assoc; cl00429 291112014303 4 probable transmembrane helices predicted for PAT0347 by TMHMM2.0 at aa 24-46, 66-88, 158-180 and 190-212 291112014304 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 291112014305 Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248 291112014306 active site 291112014307 catalytic tetrad [active] 291112014308 HMMPfam hit to PF00248, Aldo/keto reductase family, score 1.3e-119 291112014309 FtsI repressor; Provisional; Region: PRK10883 291112014310 Multicopper oxidase; Region: Cu-oxidase_3; pfam07732 291112014311 Multicopper oxidase; Region: Cu-oxidase_2; pfam07731 291112014312 HMMPfam hit to PF07731, Multicopper oxidase, score 4.9e-18 291112014313 HMMPfam hit to PF07732, Multicopper oxidase, score 1.4e-38 291112014314 1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018 291112014315 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 291112014316 putative acyl-acceptor binding pocket; other site 291112014317 3 probable transmembrane helices predicted for PAT0351 by TMHMM2.0 at aa 4-26, 97-116 and 161-183 291112014318 HMMSmart hit to SM00563, no description, score 1.1e-36 291112014319 HMMPfam hit to PF01553, Acyltransferase, score 1.8e-46 291112014320 DNA topoisomerase IV subunit A; Validated; Region: PRK05561 291112014321 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 291112014322 CAP-like domain; other site 291112014323 active site 291112014324 primary dimer interface [polypeptide binding]; other site 291112014325 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 3.7e-05 291112014326 HMMPfam hit to PF03989, DNA gyrase C-terminal domain, beta-prop, score 2.6e-05 291112014327 HMMPfam hit to PF00521, DNA gyrase/topoisomerase IV, subunit A, score 1.2e-253 291112014328 HMMSmart hit to SM00434, no description, score 1.7e-234 291112014329 DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559 291112014330 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112014331 ATP binding site [chemical binding]; other site 291112014332 Mg2+ binding site [ion binding]; other site 291112014333 G-X-G motif; other site 291112014334 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 291112014335 anchoring element; other site 291112014336 dimer interface [polypeptide binding]; other site 291112014337 ATP binding site [chemical binding]; other site 291112014338 Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718 291112014339 active site 291112014340 metal binding site [ion binding]; metal-binding site 291112014341 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 291112014342 HMMSmart hit to SM00433, no description, score 3.2e-207 291112014343 HMMPfam hit to PF00986, DNA gyrase B subunit, carboxyl terminus, score 5.5e-30 291112014344 HMMPfam hit to PF00204, DNA gyrase B, score 1.7e-55 291112014345 HMMSmart hit to SM00387, no description, score 1.8e-21 291112014346 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and H, score 1.7e-26 291112014347 esterase YqiA; Provisional; Region: PRK11071 291112014348 HMMPfam hit to PF05728, Uncharacterised protein family (UPF0227), score 2.4e-96 291112014349 Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402 291112014350 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 291112014351 active site 291112014352 metal binding site [ion binding]; metal-binding site 291112014353 hexamer interface [polypeptide binding]; other site 291112014354 HMMPfam hit to PF08413, Calcineurin-like phosphoesterase C-term, score 1.1e-34 291112014355 HMMPfam hit to PF00149, Calcineurin-like phosphoesterase, score 2e-17 291112014356 ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729 291112014357 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 291112014358 dimer interface [polypeptide binding]; other site 291112014359 ADP-ribose binding site [chemical binding]; other site 291112014360 active site 291112014361 nudix motif; other site 291112014362 metal binding site [ion binding]; metal-binding site 291112014363 HMMPfam hit to PF00293, NUDIX domain, score 1.4e-16 291112014364 outer membrane channel protein; Reviewed; Region: tolC; PRK09465 291112014365 HMMPfam hit to PF02321, Outer membrane efflux protein, score 6.3e-40 291112014366 HMMPfam hit to PF02321, Outer membrane efflux protein, score 2e-46 291112014367 hypothetical protein; Provisional; Region: PRK11653 291112014368 1 probable transmembrane helix predicted for PAT0358 by TMHMM2.0 at aa 21-38 291112014369 Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754 291112014370 HMMPfam hit to PF03738, Glutathionylspermidine synthase, score 2.1e-237 291112014371 The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363 291112014372 Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900 291112014373 putative active site [active] 291112014374 metal binding site [ion binding]; metal-binding site 291112014375 HMMPfam hit to PF02900, Catalytic LigB subunit of aromatic ring-open, score 3.9e-82 291112014376 3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353 291112014377 3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108 291112014378 HMMPfam hit to PF00926, 3,4-dihydroxy-2-butanone 4-phosphate sy, score 2.8e-127 291112014379 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960 291112014380 HMMPfam hit to PF04380, Protein of unknown function (DUF526), score 2.5e-40 291112014381 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112014382 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112014383 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112014384 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 6.9e-39 291112014385 This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990 291112014386 2 probable transmembrane helices predicted for PAT0365 by TMHMM2.0 at aa 400-422 and 429-451 291112014387 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014388 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014389 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014390 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014391 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014392 PAAR motif; Region: PAAR_motif; pfam05488 291112014393 HMMPfam hit to PF05488, PAAR motif, score 11 291112014394 HMMPfam hit to PF05488, PAAR motif, score 0.00018 291112014395 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316 291112014396 RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172 291112014397 putative ribose interaction site [chemical binding]; other site 291112014398 putative ADP binding site [chemical binding]; other site 291112014399 rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199 291112014400 active site 291112014401 nucleotide binding site [chemical binding]; other site 291112014402 HIGH motif; other site 291112014403 KMSKS motif; other site 291112014404 HMMPfam hit to PF01467, Cytidylyltransferase, score 2.3e-28 291112014405 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 5.1e-45 291112014406 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072 291112014407 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 291112014408 metal binding triad; other site 291112014409 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335 291112014410 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 291112014411 metal binding triad; other site 291112014412 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335 291112014413 HMMPfam hit to PF03710, Glutamate-ammonia ligase adenylyltransferase, score 1.1e-129 291112014414 HMMPfam hit to PF03710, Glutamate-ammonia ligase adenylyltransferase, score 3.7e-123 291112014415 Uncharacterized conserved protein [Function unknown]; Region: COG3025 291112014416 Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756 291112014417 putative active site [active] 291112014418 putative metal binding residues [ion binding]; other site 291112014419 signature motif; other site 291112014420 putative triphosphate binding site [ion binding]; other site 291112014421 HMMPfam hit to PF01928, CYTH domain, score 2.3e-42 291112014422 This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146 291112014423 dimer interface [polypeptide binding]; other site 291112014424 FMN binding site [chemical binding]; other site 291112014425 NADPH bind site [chemical binding]; other site 291112014426 HMMPfam hit to PF00881, Nitroreductase family, score 6.8e-41 291112014427 SH3 domain-containing protein; Provisional; Region: PRK10884 291112014428 Bacterial SH3 domain homologues; Region: SH3b; smart00287 291112014429 HMMSmart hit to SM00287, no description, score 7.5e-08 291112014430 1 probable transmembrane helix predicted for PAT0376 by TMHMM2.0 at aa 169-191 291112014431 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885 291112014432 Poly A polymerase head domain; Region: PolyA_pol; pfam01743 291112014433 Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627 291112014434 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 291112014435 Zn2+ binding site [ion binding]; other site 291112014436 Mg2+ binding site [ion binding]; other site 291112014437 HMMPfam hit to PF01743, Poly A polymerase family, score 7.7e-65 291112014438 HMMSmart hit to SM00471, no description, score 0.0009 291112014439 HMMPfam hit to PF01966, HD domain, score 3.9e-17 291112014440 undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281 291112014441 8 probable transmembrane helices predicted for PAT0378 by TMHMM2.0 at aa 20-42, 54-76, 91-108, 121-138, 153-172, 185-207, 217-239 and 252-271 291112014442 HMMPfam hit to PF02673, Bacitracin resistance protein BacA, score 3.5e-140 291112014443 Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534 291112014444 homooctamer interface [polypeptide binding]; other site 291112014445 active site 291112014446 HMMPfam hit to PF02152, Dihydroneopterin aldolase, score 1.1e-49 291112014447 putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220 291112014448 5 probable transmembrane helices predicted for PAT0380 by TMHMM2.0 at aa 7-29, 49-71, 78-100, 110-132 and 139-158 291112014449 HMMPfam hit to PF02660, Domain of unknown function DUF, score 6e-103 291112014450 UGMP family protein; Validated; Region: PRK09604 291112014451 Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884 291112014452 HMMPfam hit to PF00814, Glycoprotease family, score 6.1e-76 291112014453 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 291112014454 HMMPfam hit to PF01165, Ribosomal protein S21, score 2.6e-35 291112014455 DNA primase; Validated; Region: dnaG; PRK05667 291112014456 CHC2 zinc finger; Region: zf-CHC2; pfam01807 291112014457 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 291112014458 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 291112014459 active site 291112014460 metal binding site [ion binding]; metal-binding site 291112014461 interdomain interaction site; other site 291112014462 DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410 291112014463 DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278 291112014464 HMMPfam hit to PF01807, CHC2 zinc finger, score 4.6e-62 291112014465 HMMSmart hit to SM00400, no description, score 5.5e-38 291112014466 HMMPfam hit to PF08275, DNA primase catalytic core, N-terminal, score 2.4e-66 291112014467 HMMPfam hit to PF01751, Toprim domain, score 3.6e-26 291112014468 HMMSmart hit to SM00493, no description, score 2.9e-22 291112014469 HMMPfam hit to PF08278, DNA primase DnaG DnaB-binding, score 3.7e-60 291112014470 RNA polymerase sigma factor RpoD; Validated; Region: PRK05658 291112014471 Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979 291112014472 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 291112014473 Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546 291112014474 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 291112014475 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 291112014476 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 291112014477 DNA binding residues [nucleotide binding] 291112014478 HMMPfam hit to PF03979, Sigma-70 factor, region, score 1.6e-42 291112014479 HMMPfam hit to PF00140, Sigma-70 factor, region, score 2.6e-15 291112014480 HMMPfam hit to PF04546, Sigma-70, non-essential region, score 5.7e-117 291112014481 HMMPfam hit to PF04542, Sigma-70 region, score 2e-28 291112014482 HMMPfam hit to PF04539, Sigma-70 region, score 2.2e-41 291112014483 HMMPfam hit to PF04545, Sigma-70, region, score 1.9e-22 291112014484 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 291112014485 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112014486 Coenzyme A binding pocket [chemical binding]; other site 291112014487 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.9e-10 291112014488 P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192 291112014489 Int/Topo IB signature motif; other site 291112014490 HMMPfam hit to PF00589, Phage integrase family, score 4e-53 291112014491 DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869 291112014492 HMMPfam hit to PF05869, DNA N-6-adenine-methyltransferase (Dam), score 2.7e-72 291112014493 Protein of unknown function (DUF3268); Region: DUF3268; pfam11672 291112014494 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 291112014495 DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012 291112014496 active site 291112014497 catalytic site [active] 291112014498 substrate binding site [chemical binding]; other site 291112014499 1 probable transmembrane helix predicted for PAT0401 by TMHMM2.0 at aa 79-98 291112014500 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112014501 non-specific DNA binding site [nucleotide binding]; other site 291112014502 salt bridge; other site 291112014503 Predicted transcriptional regulator [Transcription]; Region: COG2932 291112014504 sequence-specific DNA binding site [nucleotide binding]; other site 291112014505 Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529 291112014506 Catalytic site [active] 291112014507 HMMPfam hit to PF00717, Peptidase S24-like, score 2.3e-11 291112014508 HMMSmart hit to SM00530, no description, score 3.9e-06 291112014509 HMMPfam hit to PF01381, Helix-turn-helix, score 2.6e-07 291112014510 Bacteriophage CII protein; Region: Phage_CII; pfam05269 291112014511 HMMPfam hit to PF05269, Bacteriophage CII protein, score 0.0012 291112014512 Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492 291112014513 HMMPfam hit to PF04492, Phage replication protein O, N-terminal, score 7.4e-85 291112014514 HMMPfam hit to PF06992, Replication P, score 5e-76 291112014515 Replication protein P; Region: Phage_lambda_P; pfam06992 291112014516 Protein of unknown function (DUF1367); Region: DUF1367; pfam07105 291112014517 HMMPfam hit to PF07105, Protein of unknown function DUF1367, score 3.6e-08 291112014518 HMMPfam hit to PF07105, Protein of unknown function DUF1367, score 2.8e-08 291112014519 Bacteriophage Lambda NinG protein; Region: NinG; pfam05766 291112014520 HMMPfam hit to PF05766, Bacteriophage Lambda NinG, score 1.7e-93 291112014521 Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530 291112014522 HMMPfam hit to PF06530, Phage antitermination Q-like, score 9.7e-48 291112014523 Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106 291112014524 HMMPfam hit to PF05106, Holin, phage lambda, score 3.2e-40 291112014525 Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737 291112014526 catalytic residues [active] 291112014527 HMMPfam hit to PF00959, Glycoside hydrolase, family 24, score 1.7e-30 291112014528 Bacteriophage lysis protein; Region: Phage_lysis; pfam03245 291112014529 HMMPfam hit to PF03245, Bacteriophage lysis protein, score 6.8e-34 291112014530 BRO family, N-terminal domain; Region: Bro-N; smart01040 291112014531 HMMPfam hit to PF02498, BRO, N-terminal, score 0.013 291112014532 Phage terminase large subunit; Region: Terminase_3; cl12054 291112014533 HMMPfam hit to PF04466, Phage terminase large subunit, score 9e-19 291112014534 phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555 291112014535 Protein of unknown function (DUF1073); Region: DUF1073; pfam06381 291112014536 Uncharacterized protein, homolog of phage Mu protein gp30 [Function unknown]; Region: COG2369 291112014537 Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072 291112014538 HMMPfam hit to PF04233, Phage putative head morphogenesis protein, SPP1 gp7, score 8e-09 291112014539 HMMPfam hit to PF02012, Glycoside hydrolase, BNR repeat, score 0.00029 291112014540 Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979 291112014541 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3566 291112014542 Septum formation initiator; Region: DivIC; cl17659 291112014543 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834 291112014544 Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950 291112014545 Protein of unknown function (DUF3383); Region: DUF3383; pfam11863 291112014546 Protein of unknown function (DUF3277); Region: DUF3277; pfam11681 291112014547 Protein of unknown function (DUF2669); Region: DUF2669; pfam10876 291112014548 Phage-related protein [Function unknown]; Region: COG5412 291112014549 ORF6N domain; Region: ORF6N; pfam10543 291112014550 Arc-like DNA binding domain; Region: Arc; pfam03869 291112014551 HMMPfam hit to PF03869, Arc-like DNA binding, score 1.3e-10 291112014552 KilA-N domain; Region: KilA-N; pfam04383 291112014553 HMMPfam hit to PF04383, KilA, N-terminal, score 3.6e-16 291112014554 phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644 291112014555 Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299 291112014556 Protein of unknown function (DUF2612); Region: DUF2612; pfam11041 291112014557 Phage Tail Collar Domain; Region: Collar; pfam07484 291112014558 HMMPfam hit to PF07484, Phage Tail Collar, score 1.2e-19 291112014559 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112014560 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 5.1e-39 291112014561 DNA methylase; Region: N6_N4_Mtase; cl17433 291112014562 HMMPfam hit to PF01555, DNA methylase, score 0.0012 291112014563 DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061 291112014564 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112014565 ATP binding site [chemical binding]; other site 291112014566 putative Mg++ binding site [ion binding]; other site 291112014567 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112014568 nucleotide binding region [chemical binding]; other site 291112014569 ATP-binding site [chemical binding]; other site 291112014570 HMMSmart hit to SM00490, no description, score 1.1e-12 291112014571 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.7e-13 291112014572 HMMSmart hit to SM00487, no description, score 1.6e-07 291112014573 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 8.4e-06 291112014574 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 3.4e-13 291112014575 CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673 291112014576 CRISPR-associated helicase Cas3, subtype I-F/YPEST; Region: cas3_yersinia; TIGR02562 291112014577 Protein of unknown function (DUF1044); Region: DUF1044; cl01955 291112014578 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112014579 non-specific DNA binding site [nucleotide binding]; other site 291112014580 salt bridge; other site 291112014581 sequence-specific DNA binding site [nucleotide binding]; other site 291112014582 HMMSmart hit to SM00530, no description, score 7.4e-07 291112014583 HMMPfam hit to PF01381, Helix-turn-helix, score 6.9e-06 291112014584 Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693 291112014585 Methyltransferase domain; Region: Methyltransf_31; pfam13847 291112014586 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112014587 S-adenosylmethionine binding site [chemical binding]; other site 291112014588 HMMPfam hit to PF02353, Cyclopropane-fatty-acyl-phospholipid, score 0.0017 291112014589 HMMPfam hit to PF08241, Methyltransferase domain, score 2.3e-07 291112014590 HMMPfam hit to PF08242, Methyltransferase domain, score 2.6e-11 291112014591 Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885 291112014592 isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150 291112014593 active site 291112014594 metal binding site [ion binding]; metal-binding site 291112014595 nudix motif; other site 291112014596 HMMPfam hit to PF00293, NUDIX domain, score 8.3e-21 291112014597 Protein of unknown function (DUF535); Region: DUF535; pfam04393 291112014598 HMMPfam hit to PF04393, Protein of unknown function (DUF535), score 2.2e-84 291112014599 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 291112014600 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 291112014601 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.6e-07 291112014602 NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902 291112014603 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930 291112014604 active site 291112014605 FMN binding site [chemical binding]; other site 291112014606 2,4-decadienoyl-CoA binding site; other site 291112014607 catalytic residue [active] 291112014608 4Fe-4S cluster binding site [ion binding]; other site 291112014609 Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446 291112014610 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500 291112014611 HMMPfam hit to PF00724, NADH:flavin oxidoreductase / NADH oxidas, score 5.5e-127 291112014612 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoredu, score 0.00012 291112014613 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoredu, score 0.00026 291112014614 serine/threonine transporter SstT; Provisional; Region: PRK13628 291112014615 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 291112014616 HMMPfam hit to PF00375, Sodium:dicarboxylate symporter family, score 2.3e-140 291112014617 9 probable transmembrane helices predicted for PAT0470 by TMHMM2.0 at aa 21-38, 48-70, 83-105, 140-162, 183-205, 215-237, 287-309, 329-351 and 358-377 291112014618 integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718 291112014619 9 probable transmembrane helices predicted for PAT0471 by TMHMM2.0 at aa 6-28, 41-63, 88-110, 115-137, 142-161, 198-220, 235-257, 264-286 and 290-312 291112014620 HMMPfam hit to PF03741, Integral membrane protein TerC family, score 1.4e-56 291112014621 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 291112014622 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 291112014623 4 probable transmembrane helices predicted for PAT0473 by TMHMM2.0 at aa 24-46, 66-88, 153-175 and 190-212 291112014624 Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957 291112014625 HMMPfam hit to PF05957, Bacterial protein of unknown function (DUF88, score 8.9e-41 291112014626 1 probable transmembrane helix predicted for PAT0474 by TMHMM2.0 at aa 80-99 291112014627 Predicted membrane protein [Function unknown]; Region: COG5393 291112014628 2 probable transmembrane helices predicted for PAT0475 by TMHMM2.0 at aa 50-72 and 82-104 291112014629 YqjK-like protein; Region: YqjK; pfam13997 291112014630 Predicted membrane protein [Function unknown]; Region: COG2259 291112014631 HMMPfam hit to PF07681, DoxX, score 3e-33 291112014632 4 probable transmembrane helices predicted for PAT0477 by TMHMM2.0 at aa 29-46, 66-88, 93-111 and 126-143 291112014633 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112014634 putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074 291112014635 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 291112014636 dimerization interface [polypeptide binding]; other site 291112014637 HMMPfam hit to PF03466, LysR substrate binding domain, score 3.1e-15 291112014638 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 2.1e-15 291112014639 Pirin-related protein [General function prediction only]; Region: COG1741 291112014640 Pirin; Region: Pirin; pfam02678 291112014641 HMMPfam hit to PF02678, Pirin, score 3.1e-33 291112014642 SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994 291112014643 Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648 291112014644 putative SAM binding site [chemical binding]; other site 291112014645 putative homodimer interface [polypeptide binding]; other site 291112014646 HMMPfam hit to PF00590, Tetrapyrrole (Corrin/Porphyrin) Methylas, score 2.9e-69 291112014647 Putative lipoprotein [General function prediction only]; Region: LppC; COG3107 291112014648 Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339 291112014649 putative ligand binding site [chemical binding]; other site 291112014650 HMMPfam hit to PF04348, LppC putative lipoprotein, score 2.9e-62 291112014651 1 probable transmembrane helix predicted for PAT0482 by TMHMM2.0 at aa 21-43 291112014652 hypothetical protein; Reviewed; Region: PRK12497 291112014653 HMMPfam hit to PF02021, Uncharacterised protein family UPF0102, score 3.4e-22 291112014654 Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006 291112014655 dimer interface [polypeptide binding]; other site 291112014656 active site 291112014657 outer membrane lipoprotein; Provisional; Region: PRK11023 291112014658 BON domain; Region: BON; pfam04972 291112014659 BON domain; Region: BON; pfam04972 291112014660 1 probable transmembrane helix predicted for PAT0485 by TMHMM2.0 at aa 4-26 291112014661 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 6.7e-10 291112014662 HMMSmart hit to SM00749, no description, score 1.6e-08 291112014663 HMMSmart hit to SM00749, no description, score 0.013 291112014664 HMMPfam hit to PF04972, Putative phospholipid-binding domain, score 9.5e-11 291112014665 monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056 291112014666 Transglycosylase; Region: Transgly; cl17702 291112014667 HMMPfam hit to PF00912, Transglycosylase, score 1.9e-74 291112014668 1 probable transmembrane helix predicted for PAT0486 by TMHMM2.0 at aa 15-37 291112014669 isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780 291112014670 Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133 291112014671 conserved cys residue [active] 291112014672 HMMPfam hit to PF01965, DJ-1/PfpI family, score 9.3e-12 291112014673 aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091 291112014674 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 291112014675 putative active site [active] 291112014676 heme pocket [chemical binding]; other site 291112014677 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112014678 dimer interface [polypeptide binding]; other site 291112014679 phosphorylation site [posttranslational modification] 291112014680 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112014681 ATP binding site [chemical binding]; other site 291112014682 Mg2+ binding site [ion binding]; other site 291112014683 G-X-G motif; other site 291112014684 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112014685 active site 291112014686 phosphorylation site [posttranslational modification] 291112014687 intermolecular recognition site; other site 291112014688 dimerization interface [polypeptide binding]; other site 291112014689 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 291112014690 putative binding surface; other site 291112014691 active site 291112014692 HMMSmart hit to SM00073, no description, score 4.8e-16 291112014693 HMMPfam hit to PF01627, Hpt domain, score 4.6e-13 291112014694 HMMPfam hit to PF00072, Response regulator receiver domain, score 2.3e-34 291112014695 HMMSmart hit to SM00448, no description, score 5.2e-28 291112014696 HMMSmart hit to SM00387, no description, score 3e-34 291112014697 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 2.2e-39 291112014698 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 7.9e-20; HMMSmart hit to SM00388, no description, score 1.9e-17 291112014699 HMMPfam hit to PF08448, PAS fold, score 2.5e-16 291112014700 HMMPfam hit to PF00989, PAS fold, score 1.3e-21 291112014701 HMMSmart hit to SM00091, no description, score 0.00018 291112014702 2 probable transmembrane helices predicted for PAT0488 by TMHMM2.0 at aa 20-42 and 55-77 291112014703 1 probable transmembrane helix predicted for PAT0489 by TMHMM2.0 at aa 12-34 291112014704 glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750 291112014705 Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713 291112014706 active site 291112014707 dimer interface [polypeptide binding]; other site 291112014708 Glutamate synthase central domain; Region: Glu_syn_central; pfam04898 291112014709 Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808 291112014710 active site 291112014711 FMN binding site [chemical binding]; other site 291112014712 substrate binding site [chemical binding]; other site 291112014713 3Fe-4S cluster binding site [ion binding]; other site 291112014714 gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982 291112014715 domain interface; other site 291112014716 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 1e-211 291112014717 HMMPfam hit to PF04898, Glutamate synthase central domain, score 2e-167 291112014718 HMMPfam hit to PF01645, Conserved region in glutamate synthas, score 2.4e-238 291112014719 HMMPfam hit to PF01493, GXGXG motif, score 5.1e-106 291112014720 glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318 291112014721 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 291112014722 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 291112014723 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidoreduc, score 6.1e-19 291112014724 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 0.00056 291112014725 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidoreduc, score 0.00044 291112014726 ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798 291112014727 HMMPfam hit to PF04386, Stringent starvation protein B, score 9.3e-82 291112014728 stringent starvation protein A; Provisional; Region: sspA; PRK09481 291112014729 GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059 291112014730 C-terminal domain interface [polypeptide binding]; other site 291112014731 putative GSH binding site (G-site) [chemical binding]; other site 291112014732 dimer interface [polypeptide binding]; other site 291112014733 C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186 291112014734 dimer interface [polypeptide binding]; other site 291112014735 N-terminal domain interface [polypeptide binding]; other site 291112014736 HMMPfam hit to PF00043, Glutathione S-transferase, C-terminal domain, score 4.5e-11 291112014737 HMMPfam hit to PF02798, Glutathione S-transferase, N-terminal domain, score 3.2e-21 291112014738 30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132 291112014739 HMMPfam hit to PF00380, Ribosomal protein S9/S16, score 1.1e-71 291112014740 Ribosomal protein L13. Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392 291112014741 23S rRNA interface [nucleotide binding]; other site 291112014742 L3 interface [polypeptide binding]; other site 291112014743 HMMPfam hit to PF00572, Ribosomal protein L13, score 1.6e-87 291112014744 Predicted ATPase [General function prediction only]; Region: COG1485 291112014745 HMMPfam hit to PF03969, AFG1-like ATPase, score 2.8e-182 291112014746 hypothetical protein; Provisional; Region: PRK11677 291112014747 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105 291112014748 HMMPfam hit to PF06295, Protein of unknown function (DUF1043), score 5.4e-75 291112014749 1 probable transmembrane helix predicted for PAT0499 by TMHMM2.0 at aa 5-24 291112014750 serine endoprotease; Provisional; Region: PRK10139 291112014751 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 291112014752 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 291112014753 protein binding site [polypeptide binding]; other site 291112014754 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 291112014755 1 probable transmembrane helix predicted for PAT0500 by TMHMM2.0 at aa 7-29 291112014756 HMMPfam hit to PF00089, Trypsin, score 5.2e-21 291112014757 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 3.3e-19 291112014758 HMMSmart hit to SM00228, no description, score 1.1e-11 291112014759 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 1.7e-10 291112014760 HMMSmart hit to SM00228, no description, score 1.3e-09 291112014761 Homeodomain-like domain; Region: HTH_23; pfam13384 291112014762 Winged helix-turn helix; Region: HTH_29; pfam13551 291112014763 Winged helix-turn helix; Region: HTH_33; pfam13592 291112014764 DDE superfamily endonuclease; Region: DDE_3; pfam13358 291112014765 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335 291112014766 serine endoprotease; Provisional; Region: PRK10898 291112014767 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 291112014768 PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 291112014769 protein binding site [polypeptide binding]; other site 291112014770 1 probable transmembrane helix predicted for PAT0502 by TMHMM2.0 at aa 5-24 291112014771 HMMPfam hit to PF00089, Trypsin, score 3e-21 291112014772 HMMPfam hit to PF00595, PDZ domain (Also known as DHR or GLGF), score 5.8e-12 291112014773 HMMSmart hit to SM00228, no description, score 1.5e-11 291112014774 This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990 291112014775 2 probable transmembrane helices predicted for PAT0504 by TMHMM2.0 at aa 397-419 and 424-446 291112014776 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014777 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014778 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014779 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 291112014780 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072 291112014781 UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555 291112014782 hinge; other site 291112014783 active site 291112014784 HMMPfam hit to PF00275, EPSP synthase (3-phosphoshikimate 1-car, score 2.8e-185 291112014785 Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007 291112014786 HMMPfam hit to PF01722, BolA-like protein, score 1.2e-32 291112014787 1 probable transmembrane helix predicted for PAT0511 by TMHMM2.0 at aa 10-32 291112014788 Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043 291112014789 anti sigma factor interaction site; other site 291112014790 regulatory phosphorylation site [posttranslational modification]; other site 291112014791 HMMPfam hit to PF01740, STAS domain, score 0.043 291112014792 ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117 291112014793 HMMPfam hit to PF05494, Toluene tolerance, Ttg2, score 7.4e-94 291112014794 ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463 291112014795 mce related protein; Region: MCE; pfam02470 291112014796 HMMPfam hit to PF02470, mce related protein, score 6.3e-22 291112014797 1 probable transmembrane helix predicted for PAT0514 by TMHMM2.0 at aa 9-31 291112014798 ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767 291112014799 conserved hypothetical integral membrane protein; Region: TIGR00056 291112014800 6 probable transmembrane helices predicted for PAT0515 by TMHMM2.0 at aa 15-37, 58-80, 90-112, 153-175, 201-221 and 241-260 291112014801 HMMPfam hit to PF02405, Domain of unknown function DUF140, score 8.7e-120 291112014802 putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831 291112014803 ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261 291112014804 Walker A/P-loop; other site 291112014805 ATP binding site [chemical binding]; other site 291112014806 Q-loop/lid; other site 291112014807 ABC transporter signature motif; other site 291112014808 Walker B; other site 291112014809 D-loop; other site 291112014810 H-loop/switch region; other site 291112014811 HMMSmart hit to SM00382, no description, score 2.3e-13 291112014812 HMMPfam hit to PF00005, ABC transporter, score 2.3e-49 291112014813 putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734 291112014814 Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699 291112014815 Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699 291112014816 9 probable transmembrane helices predicted for PAT0517 by TMHMM2.0 at aa 2-24, 34-56, 69-91, 127-149, 175-194, 204-226, 239-261, 276-293 and 300-319 291112014817 HMMPfam hit to PF01699, Sodium/calcium exchanger protein, score 1.6e-40 291112014818 HMMPfam hit to PF01699, Sodium/calcium exchanger protein, score 2.6e-41 291112014819 D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892 291112014820 KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014 291112014821 putative active site [active] 291112014822 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein. These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604 291112014823 HMMPfam hit to PF01380, SIS domain, score 6.1e-35 291112014824 HMMPfam hit to PF00571, CBS domain pair, score 4.6e-22 291112014825 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484 291112014826 HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662 291112014827 lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893 291112014828 Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835 291112014829 1 probable transmembrane helix predicted for PAT0520 by TMHMM2.0 at aa 7-24 291112014830 HMMPfam hit to PF06835, Protein of unknown function (DUF1239), score 2.5e-64 291112014831 lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894 291112014832 lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002 291112014833 HMMPfam hit to PF03968, OstA-like protein, score 1.7e-46 291112014834 1 probable transmembrane helix predicted for PAT0521 by TMHMM2.0 at aa 7-24 291112014835 lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895 291112014836 ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218 291112014837 Walker A/P-loop; other site 291112014838 ATP binding site [chemical binding]; other site 291112014839 Q-loop/lid; other site 291112014840 ABC transporter signature motif; other site 291112014841 Walker B; other site 291112014842 D-loop; other site 291112014843 H-loop/switch region; other site 291112014844 HMMSmart hit to SM00382, no description, score 1e-09 291112014845 HMMPfam hit to PF00005, ABC transporter, score 2.2e-61 291112014846 RNA polymerase factor sigma-54; Reviewed; Region: PRK05932 291112014847 Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963 291112014848 Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552 291112014849 HMMPfam hit to PF00309, Sigma-54 factor, Activator interacting do, score 3.3e-18 291112014850 HMMPfam hit to PF04963, Sigma-54 factor, core binding domain, score 4.1e-97 291112014851 HMMPfam hit to PF04552, Sigma-54, DNA binding domain, score 5.1e-106 291112014852 RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552 291112014853 30S subunit binding site; other site 291112014854 HMMPfam hit to PF02482, Sigma 54 modulation protein / S30EA r, score 5.6e-45 291112014855 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 291112014856 active site 291112014857 phosphorylation site [posttranslational modification] 291112014858 HMMPfam hit to PF00359, Phosphoenolpyruvate-dependent sugar phosph, score 1.1e-48 291112014859 P-loop ATPase protein family; Region: ATP_bind_2; pfam03668 291112014860 HMMPfam hit to PF03668, P-loop ATPase protein family, score 8.3e-210 291112014861 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 291112014862 dimerization domain swap beta strand [polypeptide binding]; other site 291112014863 regulatory protein interface [polypeptide binding]; other site 291112014864 active site 291112014865 regulatory phosphorylation site [posttranslational modification]; other site 291112014866 HMMPfam hit to PF00381, PTS HPr component phosphorylation site, score 7.2e-29 291112014867 nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753 291112014868 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 291112014869 HMMPfam hit to PF01272, Prokaryotic transcription elongation factor, score 0.0012 291112014870 Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681 291112014871 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 291112014872 HMMPfam hit to PF03681, Uncharacterised protein family (UPF0150), score 4e-18 291112014873 Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194 291112014874 Sulfatase; Region: Sulfatase; cl17466 291112014875 5 probable transmembrane helices predicted for PAT0534 by TMHMM2.0 at aa 12-30, 34-51, 58-80, 104-126 and 133-155 291112014876 HMMPfam hit to PF00884, Sulfatase, score 2.2e-25 291112014877 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 291112014878 active site 291112014879 HMMPfam hit to PF00557, metallopeptidase family M24, score 7.8e-79 291112014880 peptidase PmbA; Provisional; Region: PRK11040 291112014881 HMMPfam hit to PF01523, Putative modulator of DNA gyrase, score 9.2e-93 291112014882 hypothetical protein; Provisional; Region: PRK05255 291112014883 HMMPfam hit to PF04751, Protein of unknown function (DUF615), score 8.7e-101 291112014884 Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142 291112014885 RNAase interaction site [polypeptide binding]; other site 291112014886 HMMPfam hit to PF01337, Barstar (barnase inhibitor), score 5.1e-05 291112014887 microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th, Pb, N1, and Ms) and...; Region: microbial_RNases; cl00212 291112014888 active site 291112014889 HMMPfam hit to PF00545, ribonuclease, score 1.2e-12 291112014890 1 probable transmembrane helix predicted for PAT0539 by TMHMM2.0 at aa 4-26 291112014891 protease TldD; Provisional; Region: tldD; PRK10735 291112014892 Protein of unknown function (DUF2605); Region: DUF2605; pfam10792 291112014893 HMMPfam hit to PF01523, Putative modulator of DNA gyrase, score 6.3e-108 291112014894 nitrilase; Region: PLN02798 291112014895 Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572 291112014896 putative active site [active] 291112014897 catalytic triad [active] 291112014898 dimer interface [polypeptide binding]; other site 291112014899 HMMPfam hit to PF00795, Carbon-nitrogen hydrolase, score 1e-28 291112014900 hypothetical protein; Provisional; Region: PRK10899 291112014901 AsmA-like C-terminal region; Region: AsmA_2; pfam13502 291112014902 1 probable transmembrane helix predicted for PAT0542 by TMHMM2.0 at aa 7-29 291112014903 ribonuclease G; Provisional; Region: PRK11712 291112014904 S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453 291112014905 homodimer interface [polypeptide binding]; other site 291112014906 oligonucleotide binding site [chemical binding]; other site 291112014907 HMMPfam hit to PF00575, S1 RNA binding domain, score 1.1e-19 291112014908 HMMSmart hit to SM00316, no description, score 2.8e-09 291112014909 Maf-like protein; Region: Maf; pfam02545 291112014910 Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555 291112014911 active site 291112014912 dimer interface [polypeptide binding]; other site 291112014913 HMMPfam hit to PF02545, Maf-like protein, score 1.5e-76 291112014914 rod shape-determining protein MreD; Provisional; Region: PRK11060 291112014915 HMMPfam hit to PF04093, rod shape-determining protein MreD, score 2.2e-46 291112014916 5 probable transmembrane helices predicted for PAT0545 by TMHMM2.0 at aa 10-28, 41-63, 68-90, 97-119 and 134-151 291112014917 rod shape-determining protein MreC; Region: mreC; TIGR00219 291112014918 rod shape-determining protein MreC; Region: MreC; pfam04085 291112014919 HMMPfam hit to PF04085, rod shape-determining protein MreC, score 3.6e-67 291112014920 1 probable transmembrane helix predicted for PAT0546 by TMHMM2.0 at aa 13-32 291112014921 rod shape-determining protein MreB; Provisional; Region: PRK13927 291112014922 MreB and similar proteins; Region: MreB_like; cd10225 291112014923 nucleotide binding site [chemical binding]; other site 291112014924 Mg binding site [ion binding]; other site 291112014925 putative protofilament interaction site [polypeptide binding]; other site 291112014926 RodZ interaction site [polypeptide binding]; other site 291112014927 HMMPfam hit to PF06723, MreB/Mbl protein, score 9.3e-234 291112014928 Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288 291112014929 putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823 291112014930 NADP binding site [chemical binding]; other site 291112014931 dimer interface [polypeptide binding]; other site 291112014932 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 1.4e-07 291112014933 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 3.7e-13 291112014934 Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466 291112014935 Dehydroquinase class II; Region: DHquinase_II; pfam01220 291112014936 active site 291112014937 trimer interface [polypeptide binding]; other site 291112014938 dimer interface [polypeptide binding]; other site 291112014939 HMMPfam hit to PF01220, Dehydroquinase class II, score 2.2e-91 291112014940 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302 291112014941 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 291112014942 carboxyltransferase (CT) interaction site; other site 291112014943 biotinylation site [posttranslational modification]; other site 291112014944 HMMPfam hit to PF00364, Biotin-requiring enzyme, score 1e-35 291112014945 acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591 291112014946 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 291112014947 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 291112014948 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 291112014949 HMMPfam hit to PF00289, Carbamoyl-phosphate synthase L chain,, score 9.7e-55 291112014950 HMMPfam hit to PF08443, RimK-like ATP-grasp domain, score 0.0011 291112014951 HMMPfam hit to PF01071, Phosphoribosylglycinamide synthetase,, score 0.003 291112014952 HMMPfam hit to PF02786, Carbamoyl-phosphate synthase L chain,, score 5.1e-124 291112014953 HMMPfam hit to PF02785, Biotin carboxylase C-terminal domain, score 8.6e-67 291112014954 2 probable transmembrane helices predicted for PAT0552 by TMHMM2.0 at aa 4-23 and 36-56 291112014955 hydroxyglutarate oxidase; Provisional; Region: PRK11728 291112014956 Predicted dehydrogenase [General function prediction only]; Region: COG0579 291112014957 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 3.2e-66 291112014958 hypothetical protein; Provisional; Region: PRK10633 291112014959 HMMPfam hit to PF06196, Protein of unknown function (DUF997), score 2.7e-38 291112014960 2 probable transmembrane helices predicted for PAT0554 by TMHMM2.0 at aa 13-32 and 47-69 291112014961 Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327 291112014962 Predicted symporter [General function prediction only]; Region: DhlC; COG4147 291112014963 Na binding site [ion binding]; other site 291112014964 13 probable transmembrane helices predicted for PAT0555 by TMHMM2.0 at aa 5-24, 37-59, 72-94, 122-144, 154-176, 189-211, 239-261, 268-290, 310-332, 369-386, 391-413, 420-442 and 452-471 291112014965 HMMPfam hit to PF00474, Sodium:solute symporter family, score 4.7e-176 291112014966 Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325 291112014967 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 291112014968 HMMPfam hit to PF06325, Ribosomal protein L11 methyltransfera, score 7.6e-164 291112014969 HMMPfam hit to PF05175, Methyltransferase small domain, score 0.00022 291112014970 HMMPfam hit to PF08242, Methyltransferase domain, score 1.7e-06 291112014971 tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415 291112014972 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 291112014973 FMN binding site [chemical binding]; other site 291112014974 active site 291112014975 catalytic residues [active] 291112014976 substrate binding site [chemical binding]; other site 291112014977 HMMPfam hit to PF01180, Dihydroorotate dehydrogenase, score 0.0076 291112014978 HMMPfam hit to PF01207, Dihydrouridine synthase (Dus), score 2.5e-151 291112014979 Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901 291112014980 global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430 291112014981 HMMPfam hit to PF02954, Bacterial regulatory protein, Fis family, score 4.4e-15 291112014982 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112014983 drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710 291112014984 putative substrate translocation pore; other site 291112014985 12 probable transmembrane helices predicted for PAT0559 by TMHMM2.0 at aa 5-27, 42-61, 73-92, 96-113, 134-156, 161-183, 204-226, 241-263, 270-289, 294-316, 328-350 and 354-376 291112014986 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.4e-41 291112014987 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 291112014988 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 291112014989 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 291112014990 HMMSmart hit to SM00342, no description, score 6.7e-15 291112014991 delta endotoxin, N-terminal domain; Region: Endotoxin_N; pfam03945 291112014992 Jacalin-like lectin domain; Region: Jacalin_like; cd09302 291112014993 1 probable transmembrane helix predicted for PAT0561 by TMHMM2.0 at aa 36-58 291112014994 leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614 291112014995 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 291112014996 Walker A/P-loop; other site 291112014997 ATP binding site [chemical binding]; other site 291112014998 Q-loop/lid; other site 291112014999 ABC transporter signature motif; other site 291112015000 Walker B; other site 291112015001 D-loop; other site 291112015002 H-loop/switch region; other site 291112015003 HMMSmart hit to SM00382, no description, score 0.00015 291112015004 HMMPfam hit to PF00005, ABC transporter, score 3e-57 291112015005 leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300 291112015006 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 291112015007 Walker A/P-loop; other site 291112015008 ATP binding site [chemical binding]; other site 291112015009 Q-loop/lid; other site 291112015010 ABC transporter signature motif; other site 291112015011 Walker B; other site 291112015012 D-loop; other site 291112015013 H-loop/switch region; other site 291112015014 HMMSmart hit to SM00382, no description, score 2.5e-07 291112015015 HMMPfam hit to PF00005, ABC transporter, score 1.8e-62 291112015016 leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301 291112015017 Domain of unknown function (DUF3382); Region: DUF3382; pfam11862 291112015018 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 291112015019 TM-ABC transporter signature motif; other site 291112015020 11 probable transmembrane helices predicted for PAT0565 by TMHMM2.0 at aa 7-28, 43-65, 92-109, 114-136, 138-160, 164-186, 193-210, 261-283, 311-333, 353-375 and 382-400 291112015021 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 3.3e-65 291112015022 Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653 291112015023 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 291112015024 TM-ABC transporter signature motif; other site 291112015025 8 probable transmembrane helices predicted for PAT0566 by TMHMM2.0 at aa 15-37, 44-66, 70-92, 105-124, 153-175, 207-229, 244-266 and 282-301 291112015026 HMMPfam hit to PF02653, Branched-chain amino acid transport syst, score 1.7e-61 291112015027 ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683 291112015028 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 291112015029 dimerization interface [polypeptide binding]; other site 291112015030 ligand binding site [chemical binding]; other site 291112015031 HMMPfam hit to PF01094, Receptor family ligand binding region, score 3.5e-70 291112015032 1 probable transmembrane helix predicted for PAT0568 by TMHMM2.0 at aa 4-26 291112015033 Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568 291112015034 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 0.0032 291112015035 Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929 291112015036 HMMPfam hit to PF02595, Glycerate kinase family, score 9.2e-223 291112015037 RNA polymerase factor sigma-32; Reviewed; Region: PRK06596 291112015038 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 291112015039 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 291112015040 DNA binding residues [nucleotide binding] 291112015041 HMMPfam hit to PF04545, Sigma-70, region, score 1e-17 291112015042 HMMPfam hit to PF04542, Sigma-70 region, score 3.9e-22 291112015043 cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026 291112015044 putative protein insertion permease FtsX; Region: ftsX; TIGR00439 291112015045 HMMPfam hit to PF02687, Predicted permease, score 3.2e-21 291112015046 5 probable transmembrane helices predicted for PAT0572 by TMHMM2.0 at aa 45-67, 191-213, 244-266, 273-292 and 296-313 291112015047 cell division protein FtsE; Provisional; Region: PRK10908 291112015048 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 291112015049 Walker A/P-loop; other site 291112015050 ATP binding site [chemical binding]; other site 291112015051 Q-loop/lid; other site 291112015052 ABC transporter signature motif; other site 291112015053 Walker B; other site 291112015054 D-loop; other site 291112015055 H-loop/switch region; other site 291112015056 HMMSmart hit to SM00382, no description, score 4.7e-11 291112015057 HMMPfam hit to PF00005, ABC transporter, score 1.7e-68 291112015058 signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416 291112015059 SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881 291112015060 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 291112015061 P loop; other site 291112015062 GTP binding site [chemical binding]; other site 291112015063 HMMPfam hit to PF00448, SRP54-type protein, GTPase domain, score 1.4e-126 291112015064 HMMSmart hit to SM00382, no description, score 5.5e-10 291112015065 HMMPfam hit to PF02881, SRP54-type protein, helical bundle domain, score 3.5e-14 291112015066 N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742 291112015067 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112015068 S-adenosylmethionine binding site [chemical binding]; other site 291112015069 HMMPfam hit to PF03602, Conserved hypothetical protein, score 9.1e-86 291112015070 hypothetical protein; Provisional; Region: PRK10910 291112015071 HMMPfam hit to PF06611, Protein of unknown function (DUF1145), score 1.2e-36 291112015072 2 probable transmembrane helices predicted for PAT0576 by TMHMM2.0 at aa 5-22 and 32-51 291112015073 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112015074 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112015075 putative substrate translocation pore; other site 291112015076 12 probable transmembrane helices predicted for PAT0577 by TMHMM2.0 at aa 7-29, 40-62, 69-91, 95-117, 138-156, 160-179, 212-234, 249-271, 278-300, 304-326, 338-360 and 364-386 291112015077 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.4e-16 291112015078 zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033 291112015079 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 291112015080 metal-binding site [ion binding] 291112015081 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 291112015082 Soluble P-type ATPase [General function prediction only]; Region: COG4087 291112015083 HMMPfam hit to PF00403, Heavy-metal-associated domain, score 1.9e-11 291112015084 5 probable transmembrane helices predicted for PAT0578 by TMHMM2.0 at aa 166-188, 208-230, 369-391, 406-428 and 709-731 291112015085 HMMPfam hit to PF00122, E1-E2 ATPase, score 4.3e-87 291112015086 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 5.3e-27 291112015087 Uncharacterized protein family (UPF0156); Region: RHH_2; pfam03693 291112015088 HMMPfam hit to PF03693, Uncharacterised protein family (UPF0156), score 1.4e-36 291112015089 Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668 291112015090 HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 2.2e-19 291112015091 SirA (also known as UvrY, and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A...; Region: SirA; cd03423 291112015092 CPxP motif; other site 291112015093 HMMPfam hit to PF01206, SirA-like protein, score 5.3e-37 291112015094 hypothetical protein; Provisional; Region: PRK11212 291112015095 6 probable transmembrane helices predicted for PAT0583 by TMHMM2.0 at aa 13-35, 45-64, 71-93, 108-130, 142-164 and 184-206 291112015096 HMMPfam hit to PF02592, Uncharacterized ACR, YhhQ family COG1738, score 1.8e-66 291112015097 Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371 291112015098 Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170 291112015099 dimer interface [polypeptide binding]; other site 291112015100 active site 291112015101 metal binding site [ion binding]; metal-binding site 291112015102 HMMPfam hit to PF00465, Iron-containing alcohol dehydrogenase, score 1.3e-86 291112015103 Domain of unknown function DUF29; Region: DUF29; pfam01724 291112015104 HMMPfam hit to PF01724, Domain of unknown function DUF29, score 9.6e-66 291112015105 Domain of unknown function DUF29; Region: DUF29; pfam01724 291112015106 HMMPfam hit to PF01724, Domain of unknown function DUF29, score 1.1e-62 291112015107 sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273 291112015108 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112015109 putative substrate translocation pore; other site 291112015110 12 probable transmembrane helices predicted for PAT0587 by TMHMM2.0 at aa 26-45, 65-87, 94-116, 120-142, 161-183, 188-207, 254-273, 293-312, 319-341, 351-373, 386-408 and 412-434 291112015111 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 6.6e-51 291112015112 glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143 291112015113 Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600 291112015114 active site 291112015115 catalytic site [active] 291112015116 metal binding site [ion binding]; metal-binding site 291112015117 HMMPfam hit to PF03009, Glycerophosphoryl diester phosphodiesterase, score 2.5e-104 291112015118 poxB regulator PoxA; Provisional; Region: PRK09350 291112015119 Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268 291112015120 motif 1; other site 291112015121 dimer interface [polypeptide binding]; other site 291112015122 active site 291112015123 motif 2; other site 291112015124 motif 3; other site 291112015125 HMMPfam hit to PF00152, tRNA synthetases class II (D, K and N), score 8e-74 291112015126 HMMPfam hit to PF00587, tRNA synthetase class II core domain (G,, score 0.0069 291112015127 Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed; identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; Region: Fascin; cl00187 291112015128 Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed; identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; Region: Fascin; cl00187 291112015129 PKC phosphorylation site [posttranslational modification]; other site 291112015130 Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed; identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; Region: Fascin; cl00187 291112015131 PKC phosphorylation site [posttranslational modification]; other site 291112015132 Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed; identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; Region: Fascin; cl00187 291112015133 PKC phosphorylation site [posttranslational modification]; other site 291112015134 fumarate reductase flavoprotein subunit; Validated; Region: PRK09231 291112015135 L-aspartate oxidase; Provisional; Region: PRK06175 291112015136 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 291112015137 HMMPfam hit to PF00890, FAD binding domain, score 1.2e-157 291112015138 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidore, score 0.00042 291112015139 HMMPfam hit to PF02910, Fumarate reductase/succinate dehydroge, score 1.3e-65 291112015140 fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385 291112015141 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085 291112015142 HMMPfam hit to PF00111, 2Fe-2S iron-sulfur cluster binding domain, score 0.0055 291112015143 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00082 291112015144 Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546 291112015145 D-subunit interface [polypeptide binding]; other site 291112015146 Iron-sulfur protein interface; other site 291112015147 proximal quinone binding site [chemical binding]; other site 291112015148 HMMPfam hit to PF02300, Fumarate reductase subunit C, score 2.6e-85 291112015149 3 probable transmembrane helices predicted for PAT0596 by TMHMM2.0 at aa 27-49, 69-91 and 112-129 291112015150 Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547 291112015151 Iron-sulfur protein interface; other site 291112015152 proximal quinone binding site [chemical binding]; other site 291112015153 C-subunit interface; other site 291112015154 distal quinone binding site; other site 291112015155 HMMPfam hit to PF02313, Fumarate reductase subunit D, score 1.4e-77 291112015156 3 probable transmembrane helices predicted for PAT0597 by TMHMM2.0 at aa 13-44, 54-76 and 97-116 291112015157 multidrug efflux system protein; Provisional; Region: PRK11431 291112015158 4 probable transmembrane helices predicted for PAT0598 by TMHMM2.0 at aa 2-19, 29-48, 55-77 and 81-100 291112015159 HMMPfam hit to PF00893, Small Multidrug Resistance protein, score 4.7e-45 291112015160 elongation factor P; Validated; Region: PRK00529 291112015161 Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207 291112015162 S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470 291112015163 RNA binding site [nucleotide binding]; other site 291112015164 S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794 291112015165 RNA binding site [nucleotide binding]; other site 291112015166 HMMPfam hit to PF01132, Elongation factor P (EF-P) OB domain, score 1.2e-28 291112015167 HMMPfam hit to PF08207, Elongation factor P (EF-P) KOW-like domain, score 2.9e-32 291112015168 Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509 291112015169 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112015170 FeS/SAM binding site; other site 291112015171 HMMPfam hit to PF04055, Radical SAM superfamily, score 7.5e-08 291112015172 Domain of unknown function (DUF4156); Region: DUF4156; pfam13698 291112015173 chaperonin GroEL; Reviewed; Region: groEL; PRK12849 291112015174 GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344 291112015175 ring oligomerisation interface [polypeptide binding]; other site 291112015176 ATP/Mg binding site [chemical binding]; other site 291112015177 stacking interactions; other site 291112015178 hinge regions; other site 291112015179 HMMPfam hit to PF00118, TCP-1/cpn60 chaperonin family, score 3e-186 291112015180 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 291112015181 oligomerisation interface [polypeptide binding]; other site 291112015182 mobile loop; other site 291112015183 roof hairpin; other site 291112015184 HMMPfam hit to PF00166, Chaperonin 10 Kd subunit, score 3.8e-40 291112015185 Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030 291112015186 HMMPfam hit to PF04186, FxsA cytoplasmic membrane protein, score 1.2e-43 291112015187 3 probable transmembrane helices predicted for PAT0604 by TMHMM2.0 at aa 4-21, 28-47 and 79-101 291112015188 1 probable transmembrane helix predicted for PAT0605 by TMHMM2.0 at aa 15-37 291112015189 aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273 291112015190 Aspartase; Region: Aspartase; cd01357 291112015191 active sites [active] 291112015192 tetramer interface [polypeptide binding]; other site 291112015193 HMMPfam hit to PF00206, Lyase, score 8.8e-171 291112015194 similar to INSD:AE014075 291112015195 anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412 291112015196 Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704 291112015197 HMMPfam hit to PF03606, C4-dicarboxylate anaerobic carrier, score 0.0026 291112015198 HMMPfam hit to PF03605, Anaerobic c4-dicarboxylate membrane transpo, score 3.7e-221 291112015199 11 probable transmembrane helices predicted for PAT0608 by TMHMM2.0 at aa 10-32, 45-67, 87-109, 130-152, 167-189, 225-242, 257-279, 284-306, 326-345, 358-380 and 410-432 291112015200 thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293 291112015201 Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412 291112015202 Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788 291112015203 DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953 291112015204 DsbD alpha interface [polypeptide binding]; other site 291112015205 catalytic residues [active] 291112015206 9 probable transmembrane helices predicted for PAT0609 by TMHMM2.0 at aa 7-26, 178-200, 221-243, 253-275, 295-317, 332-354, 374-391, 395-414 and 421-438 291112015207 HMMPfam hit to PF02683, Cytochrome C biogenesis protein transmemb, score 2.1e-07 291112015208 HMMPfam hit to PF00085, Thioredoxin, score 0.00067 291112015209 putative transcriptional regulator; Provisional; Region: PRK11640 291112015210 Transposase [DNA replication, recombination, and repair]; Region: COG5421 291112015211 Region 7 291112015212 A-factor biosynthesis hotdog domain; Region: AfsA; pfam03756 291112015213 Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560 291112015214 haloacid dehalogenase-like hydrolase; Region: HAD; cl17202 291112015215 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 291112015216 HMMPfam hit to PF02627, Carboxymuconolactone decarboxylase family, score 4.9e-22 291112015217 putative acyltransferase; Provisional; Region: PRK05790 291112015218 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 291112015219 dimer interface [polypeptide binding]; other site 291112015220 active site 291112015221 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 2e-152 291112015222 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 7.5e-57 291112015223 transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766 291112015224 Transposase IS200 like; Region: Y1_Tnp; cl00848 291112015225 1 probable transmembrane helix predicted for PAT0620 by TMHMM2.0 at aa 5-22 291112015226 EamA-like transporter family; Region: EamA; pfam00892 291112015227 Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950 291112015228 EamA-like transporter family; Region: EamA; pfam00892 291112015229 10 probable transmembrane helices predicted for PAT0621 by TMHMM2.0 at aa 7-25, 40-62, 69-91, 95-117, 124-142, 152-174, 187-206, 221-243, 252-269 and 279-301 291112015230 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 2.8e-18 291112015231 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 4.5e-16 291112015232 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028 291112015233 classical (c) SDRs; Region: SDR_c; cd05233 291112015234 NAD(P) binding site [chemical binding]; other site 291112015235 active site 291112015236 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase family, score 0.00012 291112015237 HMMPfam hit to PF00106, short chain dehydrogenase, score 2.5e-14 291112015238 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112015239 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112015240 LysR substrate binding domain; Region: LysR_substrate; pfam03466 291112015241 dimerization interface [polypeptide binding]; other site 291112015242 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 6.3e-19 291112015243 HMMPfam hit to PF03466, LysR substrate binding domain, score 1.4e-23 291112015244 Transcriptional regulator [Transcription]; Region: LysR; COG0583 291112015245 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112015246 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 291112015247 dimerization interface [polypeptide binding]; other site 291112015248 substrate binding pocket [chemical binding]; other site 291112015249 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.3e-10 291112015250 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 1.1e-12 291112015251 5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; cl02059 291112015252 5 probable transmembrane helices predicted for PAT0625 by TMHMM2.0 at aa 35-57, 67-84, 91-113, 133-150 and 157-179 291112015253 Toxic anion resistance protein (TelA); Region: TelA; pfam05816 291112015254 HMMPfam hit to PF05816, Toxic anion resistance protein (TelA), score 5.3e-160 291112015255 two component system sensor kinase SsrB; Provisional; Region: PRK15369 291112015256 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112015257 active site 291112015258 phosphorylation site [posttranslational modification] 291112015259 intermolecular recognition site; other site 291112015260 dimerization interface [polypeptide binding]; other site 291112015261 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112015262 DNA binding residues [nucleotide binding] 291112015263 dimerization interface [polypeptide binding]; other site 291112015264 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR fami, score 3.4e-16; HMMSmart hit to SM00421, no description, score 1.1e-18 291112015265 HMMPfam hit to PF00072, Response regulator receiver domain, score 1.4e-32 291112015266 HMMSmart hit to SM00448, no description, score 6.7e-27 291112015267 two component system sensor kinase SsrA; Provisional; Region: PRK15347 291112015268 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 291112015269 dimerization interface [polypeptide binding]; other site 291112015270 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112015271 dimer interface [polypeptide binding]; other site 291112015272 phosphorylation site [posttranslational modification] 291112015273 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112015274 ATP binding site [chemical binding]; other site 291112015275 Mg2+ binding site [ion binding]; other site 291112015276 G-X-G motif; other site 291112015277 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112015278 active site 291112015279 phosphorylation site [posttranslational modification] 291112015280 intermolecular recognition site; other site 291112015281 dimerization interface [polypeptide binding]; other site 291112015282 HMMPfam hit to PF00072, Response regulator receiver domain, score 5.9e-29 291112015283 HMMSmart hit to SM00448, no description, score 5.1e-33 291112015284 HMMSmart hit to SM00387, no description, score 4.7e-30 291112015285 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 3.2e-34 291112015286 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 2.3e-21; HMMSmart hit to SM00388, no description, score 6.9e-20 291112015287 HMMSmart hit to SM00304, no description, score 2.9e-09 291112015288 HMMPfam hit to PF00672, HAMP domain, score 1.8e-12 291112015289 2 probable transmembrane helices predicted for PAT0628 by TMHMM2.0 at aa 13-35 and 296-318 291112015290 Protein of unknown function (DUF3442); Region: DUF3442; pfam11924 291112015291 Domain of unknown function (DUF4150); Region: DUF4150; pfam13665 291112015292 Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790 291112015293 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 291112015294 Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936 291112015295 HMMPfam hit to PF05936, Bacterial protein of unknown function (DUF87, score 6.7e-125 291112015296 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 291112015297 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 291112015298 ligand binding site [chemical binding]; other site 291112015299 HMMPfam hit to PF00691, OmpA family, score 3.4e-24 291112015300 type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348 291112015301 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 291112015302 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 291112015303 3 probable transmembrane helices predicted for PAT0634 by TMHMM2.0 at aa 13-35, 50-72 and 454-476 291112015304 HMMPfam hit to PF06761, ImcF-related, score 9.2e-58 291112015305 HMMPfam hit to PF06744, Protein of unknown function (DUF1215), score 6.9e-23 291112015306 type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363 291112015307 ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812 291112015308 HMMPfam hit to PF06812, ImpA-related N-terminal, score 1.3e-18 291112015309 Protein of unknown function (DUF770); Region: DUF770; pfam05591 291112015310 HMMPfam hit to PF05591, Protein of unknown function (DUF770), score 9.4e-87 291112015311 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3517 291112015312 Protein of unknown function (DUF877); Region: DUF877; pfam05943 291112015313 HMMPfam hit to PF05943, Protein of unknown function (DUF877), score 0 291112015314 Protein of unknown function (DUF796); Region: DUF796; pfam05638 291112015315 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 1.6e-15 291112015316 type VI secretion system FHA domain protein; Region: VI_FHA; TIGR03354 291112015317 FHA domain; Region: FHA; pfam00498 291112015318 phosphopeptide binding site; other site 291112015319 putative transposase; Provisional; Region: PRK09857 291112015320 Putative transposase, YhgA-like; Region: Transposase_31; pfam04754 291112015321 HMMPfam hit to PF04754, Putative transposase, YhgA-like, score 1.1e-129 291112015322 putative transposase; Provisional; Region: PRK09857 291112015323 S-type Pyocin; Region: Pyocin_S; pfam06958 291112015324 RelB antitoxin; Region: RelB; cl01171 291112015325 HMMPfam hit to PF04221, RelB antitoxin, score 1.1e-09 291112015326 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 291112015327 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112015328 Walker A motif; other site 291112015329 ATP binding site [chemical binding]; other site 291112015330 Walker B motif; other site 291112015331 arginine finger; other site 291112015332 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112015333 Walker A motif; other site 291112015334 ATP binding site [chemical binding]; other site 291112015335 Walker B motif; other site 291112015336 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 291112015337 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 2.1e-83 291112015338 HMMSmart hit to SM00382, no description, score 2e-09 291112015339 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 5.6e-07 291112015340 HMMSmart hit to SM00382, no description, score 6.7e-10 291112015341 HMMPfam hit to PF02861, Clp amino terminal domain, score 0.00068 291112015342 Protein of unknown function (DUF1305); Region: DUF1305; pfam06996 291112015343 HMMPfam hit to PF06996, Protein of unknown function (DUF1305), score 5e-85 291112015344 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 291112015345 Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947 291112015346 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 6.3e-221 291112015347 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 291112015348 HMMPfam hit to PF07025, Protein of unknown function (DUF1316), score 1.8e-21 291112015349 Protein of unknown function (DUF3540); Region: DUF3540; pfam12059 291112015350 Pentapeptide repeats containing protein [Function unknown]; Region: COG1357 291112015351 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 291112015352 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 5.1e-05 291112015353 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.27 291112015354 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.0019 291112015355 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.084 291112015356 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.31 291112015357 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.19 291112015358 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 1.1 291112015359 Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; pfam09937 291112015360 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 291112015361 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 291112015362 Pentapeptide repeats containing protein [Function unknown]; Region: COG1357 291112015363 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 291112015364 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 291112015365 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 1e-07 291112015366 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 4.7e-06 291112015367 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.15 291112015368 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 0.003 291112015369 HMMPfam hit to PF00805, Pentapeptide repeats (8 copies), score 2.1e-08 291112015370 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112015371 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112015372 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112015373 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 1.5e-49 291112015374 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 291112015375 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112015376 DNA binding residues [nucleotide binding] 291112015377 dimerization interface [polypeptide binding]; other site 291112015378 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 7.1e-05; HMMSmart hit to SM00421, no description, score 0.00011 291112015379 Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420 291112015380 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112015381 Coenzyme A binding pocket [chemical binding]; other site 291112015382 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 5.5e-14 291112015383 Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541 291112015384 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112015385 CoA binding site [chemical binding]; other site 291112015386 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112015387 Acyl-CoA reductase LuxC; Region: ALDH_Acyl-CoA-Red_LuxC; cd07080 291112015388 Acyl-CoA reductase (LuxC); Region: LuxC; pfam05893 291112015389 putative catalytic cysteine [active] 291112015390 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112015391 AMP binding site [chemical binding]; other site 291112015392 active site 291112015393 Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541 291112015394 acyl-activating enzyme (AAE) consensus motif; other site 291112015395 CoA binding site [chemical binding]; other site 291112015396 Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443 291112015397 HMMPfam hit to PF04443, Acyl-protein synthetase, LuxE, score 4.4e-12 291112015398 1 probable transmembrane helix predicted for PAT0658 by TMHMM2.0 at aa 84-106 291112015399 RES domain; Region: RES; cl02411 291112015400 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3515 291112015401 ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812 291112015402 ImpA domain protein; Region: DUF3702; pfam12486 291112015403 HMMPfam hit to PF06812, ImpA-related N-terminal, score 5.9e-21 291112015404 type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357 291112015405 HMMPfam hit to PF07025, Protein of unknown function (DUF1316), score 6.4e-31 291112015406 Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790 291112015407 Protein of unknown function (DUF1305); Region: DUF1305; pfam06996 291112015408 HMMPfam hit to PF06996, Protein of unknown function (DUF1305), score 3.4e-47 291112015409 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 291112015410 Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947 291112015411 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 2e-221 291112015412 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3515 291112015413 ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812 291112015414 type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362 291112015415 HMMPfam hit to PF06812, ImpA-related N-terminal, score 4.5e-25 291112015416 Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and vesicular transport]; Region: IcmF; COG3523 291112015417 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 291112015418 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 291112015419 HMMPfam hit to PF06744, Protein of unknown function (DUF1215), score 1.1e-45 291112015420 HMMPfam hit to PF06761, ImcF-related, score 2.7e-68 291112015421 2 probable transmembrane helices predicted for PAT0666 by TMHMM2.0 at aa 10-32 and 39-58 291112015422 2 probable transmembrane helices predicted for PAT0667 by TMHMM2.0 at aa 22-44 and 51-73 291112015423 PAAR motif; Region: PAAR_motif; pfam05488 291112015424 HMMPfam hit to PF05488, PAAR motif, score 2.9 291112015425 HMMPfam hit to PF05488, PAAR motif, score 0.0048 291112015426 4 probable transmembrane helices predicted for PAT0669 by TMHMM2.0 at aa 7-29, 44-66, 79-101 and 139-161 291112015427 2 probable transmembrane helices predicted for PAT0670 by TMHMM2.0 at aa 208-230 and 240-259 291112015428 4 probable transmembrane helices predicted for PAT0671 by TMHMM2.0 at aa 7-29, 47-69, 76-98 and 138-160 291112015429 2 probable transmembrane helices predicted for PAT0672 by TMHMM2.0 at aa 212-231 and 241-263 291112015430 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112015431 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 291112015432 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112015433 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112015434 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 291112015435 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 291112015436 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 1.7e-11 291112015437 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 291112015438 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112015439 Walker A motif; other site 291112015440 ATP binding site [chemical binding]; other site 291112015441 Walker B motif; other site 291112015442 arginine finger; other site 291112015443 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112015444 Walker A motif; other site 291112015445 ATP binding site [chemical binding]; other site 291112015446 Walker B motif; other site 291112015447 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 291112015448 HMMSmart hit to SM00382, no description, score 3.7e-11 291112015449 HMMPfam hit to PF07728, ATPase family associated with various cellul, score 3.4e-06 291112015450 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 7.3e-82 291112015451 HMMPfam hit to PF00004, ATPase family associated with various cellul, score 2.6e-09 291112015452 HMMSmart hit to SM00382, no description, score 9.9e-13 291112015453 HMMPfam hit to PF02861, Clp amino terminal domain, score 0.0093 291112015454 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 291112015455 HMMPfam hit to PF05638, Protein of unknown function (DUF796), score 2.9e-58 291112015456 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 291112015457 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 291112015458 ligand binding site [chemical binding]; other site 291112015459 HMMPfam hit to PF00691, OmpA family, score 1.9e-16 291112015460 3 probable transmembrane helices predicted for PAT0864 by TMHMM2.0 at aa 7-26, 30-47 and 319-341 291112015461 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 291112015462 1 probable transmembrane helix predicted for PAT0865 by TMHMM2.0 at aa 185-207 291112015463 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 291112015464 Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936 291112015465 HMMPfam hit to PF05936, Bacterial protein of unknown function (DUF87, score 4.9e-172 291112015466 type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355 291112015467 Protein of unknown function (DUF877); Region: DUF877; pfam05943 291112015468 HMMPfam hit to PF05943, Protein of unknown function (DUF877), score 2.2e-291 291112015469 Protein of unknown function (DUF770); Region: DUF770; pfam05591 291112015470 HMMPfam hit to PF05591, Protein of unknown function (DUF770), score 3.2e-83 291112015471 1 probable transmembrane helix predicted for PAT0869 by TMHMM2.0 at aa 11-33 291112015472 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112015473 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112015474 putative substrate translocation pore; other site 291112015475 12 probable transmembrane helices predicted for PAT0871 by TMHMM2.0 at aa 7-29, 44-66, 79-98, 103-125, 138-160, 165-187, 208-230, 240-259, 271-288, 293-315, 327-349 and 359-378 291112015476 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 4.3e-46 291112015477 Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323 291112015478 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675 291112015479 Probable transposase; Region: OrfB_IS605; pfam01385 291112015480 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 291112015481 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 291112015482 1 probable transmembrane helix predicted for PAT0873 by TMHMM2.0 at aa 7-24 291112015483 Peptidase family M48; Region: Peptidase_M48; cl12018 291112015484 Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501 291112015485 6 probable transmembrane helices predicted for PAT0874 by TMHMM2.0 at aa 5-24, 96-118, 139-161, 176-195, 531-553 and 563-585 291112015486 HMMPfam hit to PF01435, Peptidase family M48, score 0.0002 291112015487 Rhomboid family; Region: Rhomboid; cl11446 291112015488 HMMPfam hit to PF01694, Rhomboid family, score 1.2e-06 291112015489 6 probable transmembrane helices predicted for PAT0875 by TMHMM2.0 at aa 12-34, 54-76, 83-102, 107-129, 136-155 and 159-178 291112015490 Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; Region: HX; cl02471 291112015491 Metal binding sites [ion binding]; metal-binding site 291112015492 Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472 291112015493 HMMPfam hit to PF00045, Hemopexin, score 2.8e-10; HMMSmart hit to SM00120, no description, score 8.5e-06 291112015494 HMMPfam hit to PF07472, Fucose-binding lectin II (PA-IIL), score 1.3e-67 291112015495 Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534 291112015496 Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256 291112015497 Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255 291112015498 HMMPfam hit to PF03534, Salmonella virulence plasmid 65kDa B protein, score 2.5e-238 291112015499 HMMPfam hit to PF01839, FG-GAP repeat, score 0.0014 291112015500 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 291112015501 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 291112015502 HMMPfam hit to PF05593, RHS Repeat, score 3.5 291112015503 HMMPfam hit to PF05593, RHS Repeat, score 0.24 291112015504 HMMPfam hit to PF05593, RHS Repeat, score 6.4 291112015505 1 probable transmembrane helix predicted for PAT0882 by TMHMM2.0 at aa 5-27 291112015506 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636 291112015507 HMMPfam hit to PF02677, Uncharacterized BCR, COG1636, score 1.6e-125 291112015508 Surface antigen; Region: Bac_surface_Ag; pfam01103 291112015509 HMMPfam hit to PF01103, Surface antigen, score 0.00059 291112015510 Protein of unknown function (DUF4056); Region: DUF4056; pfam13265 291112015511 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 291112015512 HMMPfam hit to PF00419, Fimbrial protein, score 5.8e-07 291112015513 fimbrial chaperone protein PefD; Provisional; Region: PRK15211 291112015514 Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345 291112015515 Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753 291112015516 HMMPfam hit to PF00345, Gram-negative pili assembly chaperone, score 5.6e-64 291112015517 HMMPfam hit to PF02753, Gram-negative pili assembly chaperone, score 3.4e-09 291112015518 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 291112015519 PapC N-terminal domain; Region: PapC_N; pfam13954 291112015520 Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577 291112015521 PapC C-terminal domain; Region: PapC_C; pfam13953 291112015522 HMMPfam hit to PF00577, Fimbrial Usher protein, score 7.8e-272 291112015523 Fimbrial protein; Region: Fimbrial; pfam00419 291112015524 HMMPfam hit to PF00419, Fimbrial protein, score 0.0054 291112015525 hypothetical protein; Provisional; Region: PRK10356 291112015526 HMMSmart hit to SM00047, no description, score 2.5e-05 291112015527 HMMPfam hit to PF01832, Mannosyl-glycoprotein endo-beta-N-ace, score 2.7e-17 291112015528 Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696 291112015529 HMMPfam hit to PF03062, Membrane bound O-acyl transferase, MBOAT, score 1.2e-53 291112015530 SGNH_peri2; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri2; cd01829 291112015531 active site 291112015532 catalytic triad [active] 291112015533 oxyanion hole [active] 291112015534 1 probable transmembrane helix predicted for PAT0892 by TMHMM2.0 at aa 13-30 291112015535 HMMPfam hit to PF04311, Protein of unknown function (DUF459), score 4e-37 291112015536 SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053 291112015537 oxyanion hole [active] 291112015538 SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825 291112015539 active site 291112015540 oxyanion hole [active] 291112015541 catalytic triad [active] 291112015542 low affinity gluconate transporter; Provisional; Region: PRK10472 291112015543 gluconate transporter; Region: gntP; TIGR00791 291112015544 11 probable transmembrane helices predicted for PAT0894 by TMHMM2.0 at aa 4-21, 28-47, 57-79, 109-131, 146-168, 175-197, 261-283, 295-317, 332-354, 375-397 and 422-444 291112015545 HMMPfam hit to PF02447, GntP family permease, score 1.4e-220 291112015546 HMMPfam hit to PF03600, Citrate transporter, score 0.00056 291112015547 Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021 291112015548 HMMPfam hit to PF01202, Shikimate kinase, score 1.2e-06 291112015549 gluconate operon transcriptional regulator; Provisional; Region: PRK14987 291112015550 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 291112015551 DNA binding site [nucleotide binding] 291112015552 domain linker motif; other site 291112015553 Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575 291112015554 putative ligand binding site [chemical binding]; other site 291112015555 putative dimerization interface [polypeptide binding]; other site 291112015556 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 4e-12 291112015557 HMMSmart hit to SM00354, no description, score 1.2e-25 291112015558 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 8.4e-08 291112015559 protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104 291112015560 potassium transporter; Provisional; Region: PRK10750 291112015561 potassium uptake protein, TrkH family; Region: 2a38; TIGR00933 291112015562 HMMPfam hit to PF02386, Cation transport protein, score 3.9e-111 291112015563 11 probable transmembrane helices predicted for PAT0898 by TMHMM2.0 at aa 9-31, 35-57, 69-91, 133-155, 185-207, 240-262, 275-297, 332-354, 396-418, 422-444 and 456-478 291112015564 hypothetical protein; Provisional; Region: PRK11568 291112015565 Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205 291112015566 Domain of unknown function (DUF1949); Region: DUF1949; pfam09186 291112015567 HMMPfam hit to PF01205, Uncharacterized protein family UPF0029, score 7.1e-65 291112015568 proline dipeptidase; Provisional; Region: PRK13607 291112015569 Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087 291112015570 active site 291112015571 HMMPfam hit to PF00557, metallopeptidase family M24, score 5.2e-19 291112015572 multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730 291112015573 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 291112015574 substrate binding site [chemical binding]; other site 291112015575 oxyanion hole (OAH) forming residues; other site 291112015576 trimer interface [polypeptide binding]; other site 291112015577 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 291112015578 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 291112015579 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 291112015580 HMMPfam hit to PF00378, Enoyl-CoA hydratase/isomerase family, score 1.8e-79 291112015581 HMMPfam hit to PF02737, 3-hydroxyacyl-CoA dehydrogenase, NAD binding, score 1.9e-81 291112015582 HMMPfam hit to PF00725, 3-hydroxyacyl-CoA dehydrogenase, C-terminal, score 4.3e-34 291112015583 3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947 291112015584 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 291112015585 dimer interface [polypeptide binding]; other site 291112015586 active site 291112015587 HMMPfam hit to PF00108, Thiolase, N-terminal domain, score 9.1e-126 291112015588 HMMPfam hit to PF02803, Thiolase, C-terminal domain, score 9.1e-81 291112015589 FMN reductase; Validated; Region: fre; PRK08051 291112015590 NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189 291112015591 FAD binding pocket [chemical binding]; other site 291112015592 FAD binding motif [chemical binding]; other site 291112015593 phosphate binding motif [ion binding]; other site 291112015594 beta-alpha-beta structure motif; other site 291112015595 NAD binding pocket [chemical binding]; other site 291112015596 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 9.6e-32 291112015597 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 4.3e-06 291112015598 3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922 291112015599 HMMPfam hit to PF01977, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, score 5e-238 291112015600 transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014 291112015601 N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892 291112015602 HMMSmart hit to SM00738, no description, score 1.4e-29 291112015603 HMMPfam hit to PF02357, Transcription termination factor nusG, score 5.6e-30 291112015604 Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823 291112015605 dimer interface [polypeptide binding]; other site 291112015606 allosteric magnesium binding site [ion binding]; other site 291112015607 active site 291112015608 aspartate-rich active site metal binding site; other site 291112015609 Schiff base residues; other site 291112015610 HMMPfam hit to PF00490, Delta-aminolevulinic acid dehydratase, score 2.5e-190 291112015611 twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921 291112015612 6 probable transmembrane helices predicted for PAT2729 by TMHMM2.0 at aa 20-37, 74-96, 116-138, 158-180, 193-210 and 214-236 291112015613 HMMPfam hit to PF00902, Sec-independent protein translocase protein, score 4.6e-94 291112015614 mttA/Hcf106 family; Region: MttA_Hcf106; cl00788 291112015615 1 probable transmembrane helix predicted for PAT2730 by TMHMM2.0 at aa 4-21 291112015616 twin arginine translocase protein A; Provisional; Region: tatA; PRK04598 291112015617 HMMPfam hit to PF02416, mttA/Hcf106 family, score 3.2e-10 291112015618 1 probable transmembrane helix predicted for PAT2731 by TMHMM2.0 at aa 4-21 291112015619 putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750 291112015620 2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982 291112015621 1 probable transmembrane helix predicted for PAT2732 by TMHMM2.0 at aa 517-539 291112015622 HMMPfam hit to PF03109, ABC1 family, score 2.9e-53 291112015623 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165 291112015624 SCP-2 sterol transfer family; Region: SCP2; pfam02036 291112015625 HMMPfam hit to PF06843, Protein of unknown function (DUF1243), score 7.3e-75 291112015626 Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226 291112015627 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112015628 S-adenosylmethionine binding site [chemical binding]; other site 291112015629 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627 291112015630 HMMPfam hit to PF01209, ubiE/COQ5 methyltransferase family, score 7.5e-153 291112015631 HMMPfam hit to PF08241, Methyltransferase domain, score 2e-28 291112015632 HMMPfam hit to PF08242, Methyltransferase domain, score 2.4e-12 291112015633 Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322 291112015634 RmuC family; Region: RmuC; pfam02646 291112015635 HMMPfam hit to PF02646, RmuC family, score 3.8e-148 291112015636 1 probable transmembrane helix predicted for PAT2735 by TMHMM2.0 at aa 5-27 291112015637 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 291112015638 SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335 291112015639 4 probable transmembrane helices predicted for PAT2736 by TMHMM2.0 at aa 22-56, 63-85, 117-139 and 152-174 291112015640 Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350 291112015641 Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348 291112015642 uridine phosphorylase; Provisional; Region: PRK11178 291112015643 Phosphorylase superfamily; Region: PNP_UDP_1; cl00303 291112015644 HMMPfam hit to PF01048, Phosphorylase family, score 9.4e-103 291112015645 Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501 291112015646 putative substrate binding pocket [chemical binding]; other site 291112015647 AC domain interface; other site 291112015648 catalytic triad [active] 291112015649 AB domain interface; other site 291112015650 interchain disulfide; other site 291112015651 HMMPfam hit to PF01470, Pyroglutamyl peptidase, score 4e-125 291112015652 TAT (twin-arginine translocation) pathway signal sequence; Region: TAT_signal; pfam10518 291112015653 Intradiol dioxygenase supgroup. Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. They break the catechol C1-C2 bond and utilize Fe3+, as opposed to the...; Region: intradiol_dioxygenase_like; cd03457 291112015654 putative active site [active] 291112015655 HMMPfam hit to PF00775, Dioxygenase, score 7.4e-06 291112015656 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222 291112015657 CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312 291112015658 THF binding site; other site 291112015659 CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311 291112015660 substrate binding site [chemical binding]; other site 291112015661 THF binding site; other site 291112015662 zinc-binding site [ion binding]; other site 291112015663 HMMPfam hit to PF01717, Cobalamin-independent synthase, Catalytic, score 8.6e-226 291112015664 HMMPfam hit to PF08267, Cobalamin-independent synthase, N-termina, score 3e-200 291112015665 DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421 291112015666 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112015667 The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441 291112015668 putative dimerization interface [polypeptide binding]; other site 291112015669 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.3e-15 291112015670 HMMPfam hit to PF03466, LysR substrate binding domain, score 3e-44 291112015671 Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831 291112015672 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482 291112015673 HMMPfam hit to PF00999, Sodium/hydrogen exchanger family, score 2.8e-78 291112015674 11 probable transmembrane helices predicted for PAT2743 by TMHMM2.0 at aa 4-26, 46-68, 85-107, 114-136, 156-178, 185-204, 233-255, 276-298, 313-335, 361-383 and 398-420 291112015675 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 291112015676 11 probable transmembrane helices predicted for PAT2744 by TMHMM2.0 at aa 37-59, 64-86, 93-115, 120-142, 149-171, 181-203, 210-232, 258-277, 346-368, 400-422 and 435-452 291112015677 HMMPfam hit to PF00916, Sulfate transporter family, score 0.00057 291112015678 HMMPfam hit to PF00860, Permease family, score 3.7e-97 291112015679 Major Facilitator Superfamily; Region: MFS_1; pfam07690 291112015680 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112015681 putative substrate translocation pore; other site 291112015682 12 probable transmembrane helices predicted for PAT2745 by TMHMM2.0 at aa 13-35, 50-72, 79-98, 103-125, 138-160, 165-184, 204-223, 233-255, 275-294, 298-320, 332-354 and 359-378 291112015683 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 7.3e-32 291112015684 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 291112015685 8 probable transmembrane helices predicted for PAT2746 by TMHMM2.0 at aa 10-32, 39-61, 76-95, 102-121, 131-153, 174-193, 197-214 and 226-248 291112015686 HMMPfam hit to PF01925, Domain of unknown function DUF81, score 2.2e-23 291112015687 Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320 291112015688 HMMPfam hit to PF01320, Colicin immunity protein / pyocin immu, score 1.9e-18 291112015689 DNase/tRNase domain of colicin-like bacteriocin; Region: Colicin-DNase; pfam12639 291112015690 HMMPfam hit to PF01844, HNH endonuclease, score 5.9e-05 291112015691 PAAR motif; Region: PAAR_motif; pfam05488 291112015692 S-type Pyocin; Region: Pyocin_S; pfam06958 291112015693 HMMPfam hit to PF06958, S-type Pyocin, score 1.3e-55 291112015694 HMMPfam hit to PF05488, PAAR motif, score 9.9 291112015695 HMMPfam hit to PF05488, PAAR motif, score 2e-08 291112015696 class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300 291112015697 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818 291112015698 substrate binding site [chemical binding]; other site 291112015699 catalytic Zn binding site [ion binding]; other site 291112015700 NAD binding site [chemical binding]; other site 291112015701 structural Zn binding site [ion binding]; other site 291112015702 dimer interface [polypeptide binding]; other site 291112015703 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 3.3e-37 291112015704 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 4.2e-35 291112015705 S-formylglutathione hydrolase; Region: PLN02442 291112015706 S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821 291112015707 HMMPfam hit to PF00756, Putative esterase, score 4.1e-102 291112015708 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 291112015709 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 291112015710 dimer interface [polypeptide binding]; other site 291112015711 ssDNA binding site [nucleotide binding]; other site 291112015712 tetramer (dimer of dimers) interface [polypeptide binding]; other site 291112015713 putative single-stranded DNA-binding protein; Region: PHA01740 291112015714 HMMPfam hit to PF00436, Single-strand binding protein family, score 2.1e-37 291112015715 excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349 291112015716 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 291112015717 Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206 291112015718 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 291112015719 ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271 291112015720 HMMPfam hit to PF00005, ABC transporter, score 1.7e-44 291112015721 Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227 291112015722 HMMPfam hit to PF04227, Indigoidine synthase A like protein, score 1.8e-204 291112015723 putative kinase; Provisional; Region: PRK09954 291112015724 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 291112015725 putative DNA binding site [nucleotide binding]; other site 291112015726 putative Zn2+ binding site [ion binding]; other site 291112015727 YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941 291112015728 substrate binding site [chemical binding]; other site 291112015729 ATP binding site [chemical binding]; other site 291112015730 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 1.1e-68 291112015731 HMMPfam hit to PF08279, HTH domain, score 3.5e-05 291112015732 aromatic amino acid aminotransferase; Provisional; Region: PRK09257 291112015733 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 291112015734 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112015735 homodimer interface [polypeptide binding]; other site 291112015736 catalytic residue [active] 291112015737 HMMPfam hit to PF00155, Aminotransferase class I and II, score 2.4e-106 291112015738 alanine racemase; Reviewed; Region: alr; PRK00053 291112015739 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827 291112015740 active site 291112015741 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 291112015742 substrate binding site [chemical binding]; other site 291112015743 catalytic residues [active] 291112015744 dimer interface [polypeptide binding]; other site 291112015745 HMMPfam hit to PF00842, Alanine racemase, C-terminal domain, score 9.4e-64 291112015746 HMMPfam hit to PF01168, Alanine racemase, N-terminal domain, score 2e-91 291112015747 replicative DNA helicase; Provisional; Region: PRK08006 291112015748 DnaB-like helicase N terminal domain; Region: DnaB; pfam00772 291112015749 DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984 291112015750 Walker A motif; other site 291112015751 ATP binding site [chemical binding]; other site 291112015752 Walker B motif; other site 291112015753 DNA binding loops [nucleotide binding] 291112015754 HMMSmart hit to SM00382, no description, score 0.00084 291112015755 HMMPfam hit to PF03796, DnaB-like helicase C terminal domain, score 2.3e-136 291112015756 HMMPfam hit to PF00772, DnaB-like helicase N terminal domain, score 7.4e-55 291112015757 quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754 291112015758 Quinone oxidoreductase (QOR); Region: QOR2; cd05286 291112015759 NADP binding site [chemical binding]; other site 291112015760 dimer interface [polypeptide binding]; other site 291112015761 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 6.6e-20 291112015762 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 1.4e-36 291112015763 tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815 291112015764 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 291112015765 FMN binding site [chemical binding]; other site 291112015766 active site 291112015767 catalytic residues [active] 291112015768 substrate binding site [chemical binding]; other site 291112015769 HMMPfam hit to PF01207, Dihydrouridine synthase (Dus), score 2.4e-133 291112015770 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903 291112015771 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 291112015772 active site 291112015773 HMMPfam hit to PF00903, Glyoxalase/Bleomycin resistance protein/Di, score 7.1e-05 291112015774 6 probable transmembrane helices predicted for PAT2767 by TMHMM2.0 at aa 12-34, 44-66, 71-93, 117-139, 146-168 and 178-200 291112015775 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 291112015776 non-specific DNA binding site [nucleotide binding]; other site 291112015777 salt bridge; other site 291112015778 sequence-specific DNA binding site [nucleotide binding]; other site 291112015779 Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693 291112015780 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112015781 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 1.4e-36 291112015782 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112015783 L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2. This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737 291112015784 teramer interface [polypeptide binding]; other site 291112015785 FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070 291112015786 active site 291112015787 FMN binding site [chemical binding]; other site 291112015788 catalytic residues [active] 291112015789 1 probable transmembrane helix predicted for PAT2772 by TMHMM2.0 at aa 7-29 291112015790 HMMPfam hit to PF01070, FMN-dependent dehydrogenase, score 2.2e-142 291112015791 Uncharacterized conserved protein [Function unknown]; Region: COG2353 291112015792 HMMPfam hit to PF04264, YceI like family, score 7e-52 291112015793 hypothetical protein; Provisional; Region: PRK11380 291112015794 2 probable transmembrane helices predicted for PAT2774 by TMHMM2.0 at aa 45-67 and 82-101 291112015795 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 291112015796 metal binding site 2 [ion binding]; metal-binding site 291112015797 putative DNA binding helix; other site 291112015798 metal binding site 1 [ion binding]; metal-binding site 291112015799 dimer interface [polypeptide binding]; other site 291112015800 structural Zn2+ binding site [ion binding]; other site 291112015801 HMMPfam hit to PF01475, Ferric uptake regulator family, score 2.3e-07 291112015802 LexA repressor; Validated; Region: PRK00215 291112015803 LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726 291112015804 Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529 291112015805 Catalytic site [active] 291112015806 HMMPfam hit to PF00717, Peptidase S24-like, score 8e-22 291112015807 HMMPfam hit to PF01726, LexA DNA binding domain, score 5.3e-36 291112015808 Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818 291112015809 3 probable transmembrane helices predicted for PAT2778 by TMHMM2.0 at aa 36-54, 58-80 and 100-122 291112015810 HMMPfam hit to PF01219, Prokaryotic diacylglycerol kinase, score 5.6e-51 291112015811 glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703 291112015812 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993 291112015813 putative acyl-acceptor binding pocket; other site 291112015814 HMMPfam hit to PF01553, Acyltransferase, score 1.5e-40 291112015815 HMMSmart hit to SM00563, no description, score 7.2e-28 291112015816 4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848 291112015817 UbiA prenyltransferase family; Region: UbiA; pfam01040 291112015818 HMMPfam hit to PF01040, UbiA prenyltransferase family, score 1.5e-80 291112015819 7 probable transmembrane helices predicted for PAT2780 by TMHMM2.0 at aa 21-38, 48-70, 98-132, 164-183, 213-231, 235-252 and 264-286 291112015820 chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655 291112015821 HMMPfam hit to PF04345, Chorismate lyase, score 1.9e-29 291112015822 glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179 291112015823 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015 291112015824 active site 291112015825 dimer interface [polypeptide binding]; other site 291112015826 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016 291112015827 dimer interface [polypeptide binding]; other site 291112015828 active site 291112015829 HMMPfam hit to PF00342, Phosphoglucose isomerase, score 0 291112015830 aspartate kinase III; Validated; Region: PRK09084 291112015831 Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452 291112015832 nucleotide binding site [chemical binding]; other site 291112015833 substrate binding site [chemical binding]; other site 291112015834 ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932 291112015835 lysine allosteric regulatory site; other site 291112015836 dimer interface [polypeptide binding]; other site 291112015837 ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917 291112015838 dimer interface [polypeptide binding]; other site 291112015839 HMMPfam hit to PF00696, Amino acid kinase family, score 3.1e-56 291112015840 HMMPfam hit to PF01842, ACT domain, score 0.0057 291112015841 Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715 291112015842 Mrr N-terminal domain; Region: Mrr_N; pfam14338 291112015843 Restriction endonuclease; Region: Mrr_cat; pfam04471 291112015844 HMMPfam hit to PF04471, Restriction endonuclease, score 9.3e-46 291112015845 Part of AAA domain; Region: AAA_19; pfam13245 291112015846 Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112 291112015847 AAA domain; Region: AAA_12; pfam13087 291112015848 Domain of unknown function (DUF4145); Region: DUF4145; pfam13643 291112015849 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096 291112015850 Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958 291112015851 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112015852 ATP binding site [chemical binding]; other site 291112015853 putative Mg++ binding site [ion binding]; other site 291112015854 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351 291112015855 HMMPfam hit to PF04313, Type I restriction enzyme R protein N termin, score 2.6e-10 291112015856 HMMSmart hit to SM00487, no description, score 1.4e-14 291112015857 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 1.1e-33 291112015858 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.9e-06 291112015859 HsdM N-terminal domain; Region: HsdM_N; pfam12161 291112015860 N-6 DNA Methylase; Region: N6_Mtase; pfam02384 291112015861 Methyltransferase domain; Region: Methyltransf_26; pfam13659 291112015862 HMMPfam hit to PF02384, N-6 DNA Methylase, score 5e-38 291112015863 Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732 291112015864 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 291112015865 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 291112015866 HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 5e-26 291112015867 HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 1.8e-15 291112015868 RNA polymerase sigma factor FecI; Provisional; Region: PRK09651 291112015869 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 291112015870 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 291112015871 DNA binding residues [nucleotide binding] 291112015872 HMMPfam hit to PF04542, Sigma-70 region, score 4.5e-15 291112015873 HMMPfam hit to PF08281, Sigma-70, region, score 1.3e-16 291112015874 HMMPfam hit to PF04545, Sigma-70, region, score 1.6e-06 291112015875 fec operon regulator FecR; Reviewed; Region: PRK09774 291112015876 FecR protein; Region: FecR; pfam04773 291112015877 HMMPfam hit to PF04773, FecR protein, score 1.7e-42 291112015878 Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772 291112015879 Secretin and TonB N terminus short domain; Region: STN; smart00965 291112015880 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 291112015881 N-terminal plug; other site 291112015882 ligand-binding site [chemical binding]; other site 291112015883 HMMPfam hit to PF07660, Secretin and TonB N terminus short domai, score 9.7e-09 291112015884 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.3e-18 291112015885 HMMPfam hit to PF00593, TonB dependent receptor, score 2.4e-26 291112015886 iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411 291112015887 Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146 291112015888 siderophore binding site; other site 291112015889 1 probable transmembrane helix predicted for PAT2792 by TMHMM2.0 at aa 7-26 291112015890 HMMPfam hit to PF01497, Periplasmic binding protein, score 3.2e-60 291112015891 ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779 291112015892 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112015893 ABC-ATPase subunit interface; other site 291112015894 dimer interface [polypeptide binding]; other site 291112015895 putative PBP binding regions; other site 291112015896 8 probable transmembrane helices predicted for PAT2793 by TMHMM2.0 at aa 12-34, 59-81, 94-116, 121-143, 152-174, 198-220, 241-263 and 305-327 291112015897 HMMPfam hit to PF01032, FecCD transport family, score 6.7e-120 291112015898 HMMPfam hit to PF00950, ABC 3 transport family, score 0.0015 291112015899 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 291112015900 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 291112015901 ABC-ATPase subunit interface; other site 291112015902 dimer interface [polypeptide binding]; other site 291112015903 putative PBP binding regions; other site 291112015904 8 probable transmembrane helices predicted for PAT2794 by TMHMM2.0 at aa 5-24, 50-72, 85-103, 107-129, 136-158, 230-252, 265-287 and 297-315 291112015905 HMMPfam hit to PF01032, FecCD transport family, score 1.7e-129 291112015906 iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231 291112015907 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 291112015908 Walker A/P-loop; other site 291112015909 ATP binding site [chemical binding]; other site 291112015910 Q-loop/lid; other site 291112015911 ABC transporter signature motif; other site 291112015912 Walker B; other site 291112015913 D-loop; other site 291112015914 H-loop/switch region; other site 291112015915 HMMSmart hit to SM00382, no description, score 1e-15 291112015916 HMMPfam hit to PF00005, ABC transporter, score 3.3e-64 291112015917 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112015918 DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863 291112015919 DNA methylase; Region: N6_N4_Mtase; pfam01555 291112015920 HMMPfam hit to PF01555, DNA methylase, score 3.8e-43 291112015921 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112015922 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112015923 non-specific DNA binding site [nucleotide binding]; other site 291112015924 salt bridge; other site 291112015925 sequence-specific DNA binding site [nucleotide binding]; other site 291112015926 HMMSmart hit to SM00530, no description, score 1e-10 291112015927 HMMPfam hit to PF01381, Helix-turn-helix, score 1.9e-11 291112015928 Restriction endonuclease BamHI; Region: BamHI; pfam02923 291112015929 putative transposase OrfB; Reviewed; Region: PHA02517 291112015930 HTH-like domain; Region: HTH_21; pfam13276 291112015931 Integrase core domain; Region: rve; pfam00665 291112015932 Integrase core domain; Region: rve_2; pfam13333 291112015933 HMMPfam hit to PF00665, Integrase core domain, score 2.2e-42 291112015934 Homeodomain-like domain; Region: HTH_23; cl17451 291112015935 Helix-turn-helix domain; Region: HTH_28; pfam13518 291112015936 Domain of unknown function (DUF4102); Region: DUF4102; pfam13356 291112015937 Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843 291112015938 Methyltransferase domain; Region: Methyltransf_27; pfam13708 291112015939 Protein of unknown function (DUF1219); Region: DUF1219; pfam06755 291112015940 YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154 291112015941 HMMPfam hit to PF06154, YagB/YeeU/YfjZ family, score 2.6e-56 291112015942 Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071 291112015943 MPN+ (JAMM) motif; other site 291112015944 Zinc-binding site [ion binding]; other site 291112015945 HMMPfam hit to PF04002, RadC, DNA repair protein, score 1.7e-64 291112015946 Domain of unknown function (DUF932); Region: DUF932; pfam06067 291112015947 HMMPfam hit to PF06067, Domain of unknown function (DUF932), score 8.7e-219 291112015948 Predicted transcriptional regulator [Transcription]; Region: COG2378 291112015949 WYL domain; Region: WYL; pfam13280 291112015950 Predicted GTPase [General function prediction only]; Region: COG3596 291112015951 YfjP GTPase; Region: YfjP; cd11383 291112015952 G1 box; other site 291112015953 GTP/Mg2+ binding site [chemical binding]; other site 291112015954 Switch I region; other site 291112015955 G2 box; other site 291112015956 Switch II region; other site 291112015957 G3 box; other site 291112015958 G4 box; other site 291112015959 G5 box; other site 291112015960 HMMPfam hit to PF01926, GTPase of unknown function, score 3.2e-18 291112015961 Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311 291112015962 HMMPfam hit to PF05930, Prophage CP4-57 regulatory protein (AlpA), score 1.1e-20 291112015963 Protein of unknown function (DUF3296); Region: DUF3296; pfam11726 291112015964 type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497 291112015965 HsdM N-terminal domain; Region: HsdM_N; pfam12161 291112015966 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112015967 S-adenosylmethionine binding site [chemical binding]; other site 291112015968 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 291112015969 Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732 291112015970 HMMPfam hit to PF02384, N-6 DNA Methylase, score 1.4e-186 291112015971 HMMPfam hit to PF01420, Type I restriction modification DNA speci, score 2.3e-29 291112015972 AAA domain; Region: AAA_13; pfam13166 291112015973 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610 291112015974 Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313 291112015975 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112015976 ATP binding site [chemical binding]; other site 291112015977 putative Mg++ binding site [ion binding]; other site 291112015978 HMMPfam hit to PF04313, Type I restriction enzyme R protein N termin, score 5e-59 291112015979 HMMSmart hit to SM00487, no description, score 5.1e-14 291112015980 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 3.9e-51 291112015981 Protein of unknown function (DUF511); Region: DUF511; cl01114 291112015982 Protein of unknown function (DUF511); Region: DUF511; cl01114 291112015983 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112015984 DNA binding site [nucleotide binding] 291112015985 active site 291112015986 Int/Topo IB signature motif; other site 291112015987 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 291112015988 Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834 291112015989 Integrase; Region: Integrase_1; pfam12835 291112015990 Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311 291112015991 HMMPfam hit to PF05930, Prophage CP4-57 regulatory protein (AlpA), score 2.7e-27 291112015992 Ash protein family; Region: Phage_ASH; pfam10554 291112015993 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643 291112015994 Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778 291112015995 TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029 291112015996 active site 291112015997 metal binding site [ion binding]; metal-binding site 291112015998 interdomain interaction site; other site 291112015999 AAA domain; Region: AAA_25; pfam13481 291112016000 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 291112016001 Walker A motif; other site 291112016002 ATP binding site [chemical binding]; other site 291112016003 Walker B motif; other site 291112016004 Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423 291112016005 integrase; Provisional; Region: PRK09692 291112016006 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 291112016007 active site 291112016008 Int/Topo IB signature motif; other site 291112016009 HMMPfam hit to PF00589, Phage integrase family, score 1.8e-32 291112016010 beta-lactam binding protein AmpH; Provisional; Region: PRK10662 291112016011 Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680 291112016012 HMMPfam hit to PF00144, Beta-lactamase, score 1.1e-60 291112016013 lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071 291112016014 Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739 291112016015 HMMPfam hit to PF03739, Predicted permease YjgP/YjgQ family, score 1.1e-93 291112016016 6 probable transmembrane helices predicted for PAT2833 by TMHMM2.0 at aa 12-31, 62-81, 102-124, 277-296, 303-325 and 335-354 291112016017 lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120 291112016018 Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739 291112016019 HMMPfam hit to PF03739, Predicted permease YjgP/YjgQ family, score 4.5e-74 291112016020 6 probable transmembrane helices predicted for PAT2834 by TMHMM2.0 at aa 17-39, 54-76, 97-119, 267-289, 296-313 and 328-347 291112016021 multifunctional aminopeptidase A; Provisional; Region: PRK00913 291112016022 Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433 291112016023 interface (dimer of trimers) [polypeptide binding]; other site 291112016024 Substrate-binding/catalytic site; other site 291112016025 Zn-binding sites [ion binding]; other site 291112016026 HMMPfam hit to PF02789, Cytosol aminopeptidase family, N-term, score 1.1e-42 291112016027 HMMPfam hit to PF00883, Cytosol aminopeptidase family, cataly, score 8.5e-194 291112016028 DNA polymerase III subunit chi; Validated; Region: PRK05728 291112016029 HMMPfam hit to PF04364, DNA polymerase III chi subunit, HolC, score 8.8e-66 291112016030 valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729 291112016031 catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817 291112016032 HIGH motif; other site 291112016033 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 291112016034 catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817 291112016035 active site 291112016036 KMSKS motif; other site 291112016037 Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962 291112016038 tRNA binding surface [nucleotide binding]; other site 291112016039 anticodon binding site; other site 291112016040 Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458 291112016041 HMMPfam hit to PF00133, tRNA synthetases class I (I, L, M and V), score 0 291112016042 HMMPfam hit to PF08264, Anticodon-binding domain, score 3.2e-65 291112016043 Homeodomain-like domain; Region: HTH_23; cl17451 291112016044 Helix-turn-helix domain; Region: HTH_28; pfam13518 291112016045 putative transposase OrfB; Reviewed; Region: PHA02517 291112016046 HTH-like domain; Region: HTH_21; pfam13276 291112016047 Integrase core domain; Region: rve; pfam00665 291112016048 Integrase core domain; Region: rve_2; pfam13333 291112016049 HMMPfam hit to PF00665, Integrase core domain, score 2.2e-42 291112016050 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 291112016051 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112016052 substrate binding pocket [chemical binding]; other site 291112016053 membrane-bound complex binding site; other site 291112016054 hinge residues; other site 291112016055 HMMSmart hit to SM00062, no description, score 6.4e-64 291112016056 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.2e-79 291112016057 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 291112016058 dimer interface [polypeptide binding]; other site 291112016059 conserved gate region; other site 291112016060 putative PBP binding loops; other site 291112016061 ABC-ATPase subunit interface; other site 291112016062 HMMPfam hit to PF00528, Binding-protein-dependent transport syst, score 3e-27 291112016063 4 probable transmembrane helices predicted for PAT2841 by TMHMM2.0 at aa 20-42, 55-77, 82-104 and 188-210 291112016064 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 291112016065 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 291112016066 Walker A/P-loop; other site 291112016067 ATP binding site [chemical binding]; other site 291112016068 Q-loop/lid; other site 291112016069 ABC transporter signature motif; other site 291112016070 Walker B; other site 291112016071 D-loop; other site 291112016072 H-loop/switch region; other site 291112016073 HMMSmart hit to SM00382, no description, score 3.2e-16 291112016074 HMMPfam hit to PF00005, ABC transporter, score 1.7e-68 291112016075 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 291112016076 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112016077 substrate binding pocket [chemical binding]; other site 291112016078 membrane-bound complex binding site; other site 291112016079 hinge residues; other site 291112016080 HMMSmart hit to SM00062, no description, score 1.2e-75 291112016081 HMMPfam hit to PF00497, Bacterial extracellular solute-binding prot, score 1.5e-94 291112016082 Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492 291112016083 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 291112016084 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 291112016085 6 probable transmembrane helices predicted for PAT2845 by TMHMM2.0 at aa 10-32, 45-67, 77-99, 119-141, 156-178 and 191-212 291112016086 HMMPfam hit to PF01810, LysE type translocator, score 0.00011 291112016087 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076 291112016088 RNase E inhibitor protein; Provisional; Region: PRK11191 291112016089 HMMPfam hit to PF06877, Protein of unknown function (DUF1260), score 1.3e-47 291112016090 ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515 291112016091 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 291112016092 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 291112016093 HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 3.8e-76 291112016094 HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 3.1e-89 291112016095 Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540 291112016096 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 291112016097 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 291112016098 HMMPfam hit to PF02729, Aspartate/ornithine carbamoyltransferase, ca, score 1.4e-70 291112016099 Region 8 291112016100 HMMPfam hit to PF00185, Aspartate/ornithine carbamoyltransferase, As, score 4.8e-58 291112016101 aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893 291112016102 Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948 291112016103 Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748 291112016104 HMMPfam hit to PF01948, Aspartate carbamoyltransferase regulatory ch, score 4.4e-60 291112016105 HMMPfam hit to PF02748, Aspartate carbamoyltransferase regulatory ch, score 7e-19 291112016106 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 291112016107 homotrimer interaction site [polypeptide binding]; other site 291112016108 putative active site [active] 291112016109 HMMPfam hit to PF01042, Endoribonuclease L-PSP, score 1e-61 291112016110 anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263 291112016111 ATP cone domain; Region: ATP-cone; pfam03477 291112016112 Class III ribonucleotide reductase; Region: RNR_III; cd01675 291112016113 effector binding site; other site 291112016114 active site 291112016115 Zn binding site [ion binding]; other site 291112016116 glycine loop; other site 291112016117 HMMPfam hit to PF03477, ATP cone domain, score 1.6e-26 291112016118 HMMPfam hit to PF01228, Glycine radical, score 1.4e-52 291112016119 4Fe-4S single cluster domain; Region: Fer4_12; pfam13353 291112016120 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 291112016121 FeS/SAM binding site; other site 291112016122 hypothetical protein; Provisional; Region: PRK03467 291112016123 Protein of unknown function (DUF1471); Region: DUF1471; pfam07338 291112016124 HMMPfam hit to PF07338, Protein of unknown function (DUF1471), score 5.5e-15 291112016125 The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456 291112016126 GIY-YIG motif/motif A; other site 291112016127 putative active site [active] 291112016128 putative metal binding site [ion binding]; other site 291112016129 HMMPfam hit to PF01541, GIY-YIG catalytic domain, score 3.7e-13 291112016130 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 291112016131 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112016132 Coenzyme A binding pocket [chemical binding]; other site 291112016133 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 2.3e-14 291112016134 SCP-2 sterol transfer family; Region: SCP2; cl01225 291112016135 prenyltransferase; Reviewed; Region: ubiA; PRK05951 291112016136 UbiA prenyltransferase family; Region: UbiA; pfam01040 291112016137 9 probable transmembrane helices predicted for PAT2859 by TMHMM2.0 at aa 24-46, 51-73, 100-119, 124-146, 153-175, 180-202, 227-249, 254-271 and 291-313 291112016138 HMMPfam hit to PF01040, UbiA prenyltransferase family, score 0.0001 291112016139 Class I hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classI; cd00643 291112016140 tetramerization interface [polypeptide binding]; other site 291112016141 substrate binding pocket [chemical binding]; other site 291112016142 catalytic residues [active] 291112016143 inhibitor binding sites; inhibition site 291112016144 NADP(H) binding site [chemical binding]; other site 291112016145 Phosphotransferase enzyme family; Region: APH; pfam01636 291112016146 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 291112016147 substrate binding site [chemical binding]; other site 291112016148 HMMPfam hit to PF00368, Hydroxymethylglutaryl-coenzyme A reductas, score 5.3e-31 291112016149 phosphoenolpyruvate synthase; Validated; Region: PRK06241 291112016150 Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326 291112016151 PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391 291112016152 HMMPfam hit to PF01326, Pyruvate phosphate dikinase, PEP/pyruva, score 9.4e-33 291112016153 HMMPfam hit to PF00391, PEP-utilising enzyme, mobile domain, score 8.5e-25 291112016154 peptide synthase; Provisional; Region: PRK09274 291112016155 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 291112016156 acyl-activating enzyme (AAE) consensus motif; other site 291112016157 AMP binding site [chemical binding]; other site 291112016158 active site 291112016159 CoA binding site [chemical binding]; other site 291112016160 HMMPfam hit to PF00501, AMP-binding enzyme, score 5.9e-52 291112016161 1 probable transmembrane helix predicted for PAT2863 by TMHMM2.0 at aa 60-82 291112016162 Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183 291112016163 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066 291112016164 7 probable transmembrane helices predicted for PAT2864 by TMHMM2.0 at aa 15-32, 35-57, 72-90, 95-114, 124-146, 153-172 and 182-204 291112016165 HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 9.4e-11 291112016166 Putative integral membrane protein DUF46; Region: DUF46; cl17511 291112016167 5 probable transmembrane helices predicted for PAT2865 by TMHMM2.0 at aa 5-27, 48-67, 77-99, 124-143 and 153-175 291112016168 1 probable transmembrane helix predicted for PAT2866 by TMHMM2.0 at aa 7-29 291112016169 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 291112016170 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 291112016171 6 probable transmembrane helices predicted for PAT2867 by TMHMM2.0 at aa 21-41, 174-196, 217-239, 254-273, 280-302 and 340-362 291112016172 HMMPfam hit to PF01061, ABC-2 type transporter, score 1.3e-06 291112016173 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 291112016174 6 probable transmembrane helices predicted for PAT2868 by TMHMM2.0 at aa 25-47, 187-209, 230-252, 262-284, 291-310 and 344-366 291112016175 HMMPfam hit to PF01061, ABC-2 type transporter, score 0.0051 291112016176 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112016177 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112016178 HMMPfam hit to PF00529, HlyD family secretion protein, score 0.00075 291112016179 1 probable transmembrane helix predicted for PAT2869 by TMHMM2.0 at aa 5-22 291112016180 Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275 291112016181 5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694 291112016182 GAF domain; Region: GAF_3; pfam13492 291112016183 Histidine kinase; Region: His_kinase; pfam06580 291112016184 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112016185 ATP binding site [chemical binding]; other site 291112016186 Mg2+ binding site [ion binding]; other site 291112016187 G-X-G motif; other site 291112016188 6 probable transmembrane helices predicted for PAT2870 by TMHMM2.0 at aa 15-37, 44-63, 73-95, 107-129, 140-162 and 169-191 291112016189 HMMPfam hit to PF07694, 5TMR of 5TMR-LYT, score 5.6e-39 291112016190 HMMSmart hit to SM00065, no description, score 4.8e-05 291112016191 HMMPfam hit to PF01590, GAF domain, score 0.0004 291112016192 HMMPfam hit to PF06580, Histidine kinase, score 6.1e-39 291112016193 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HS, score 2.6e-10 291112016194 putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697 291112016195 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112016196 active site 291112016197 phosphorylation site [posttranslational modification] 291112016198 intermolecular recognition site; other site 291112016199 dimerization interface [polypeptide binding]; other site 291112016200 LytTr DNA-binding domain; Region: LytTR; pfam04397 291112016201 HMMPfam hit to PF00072, Response regulator receiver domain, score 8.6e-35 291112016202 HMMSmart hit to SM00448, no description, score 1.5e-27 291112016203 HMMPfam hit to PF04397, LytTr DNA-binding domain, score 9e-26 291112016204 Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966 291112016205 Carbon starvation protein CstA; Region: CstA; pfam02554 291112016206 C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722 291112016207 HMMPfam hit to PF02554, Carbon starvation protein CstA, score 8.2e-200 291112016208 15 probable transmembrane helices predicted for PAT2872 by TMHMM2.0 at aa 4-26, 56-78, 88-110, 123-145, 160-182, 189-211, 221-243, 255-277, 292-314, 327-349, 418-435, 462-481, 491-513, 520-542 and 557-579 291112016209 Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513 291112016210 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 291112016211 ATP binding site [chemical binding]; other site 291112016212 Mg++ binding site [ion binding]; other site 291112016213 motif III; other site 291112016214 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112016215 nucleotide binding region [chemical binding]; other site 291112016216 ATP-binding site [chemical binding]; other site 291112016217 RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499 291112016218 putative RNA binding site [nucleotide binding]; other site 291112016219 HMMPfam hit to PF03880, DbpA RNA binding domain, score 7.8e-41 291112016220 HMMSmart hit to SM00490, no description, score 4.6e-32 291112016221 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.9e-33 291112016222 HMMSmart hit to SM00487, no description, score 1.7e-65 291112016223 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 4.5e-74 291112016224 lipoprotein NlpI; Provisional; Region: PRK11189 291112016225 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 291112016226 binding surface 291112016227 TPR motif; other site 291112016228 HMMSmart hit to SM00028, no description, score 3.7e+02 291112016229 HMMSmart hit to SM00028, no description, score 3.6e+02 291112016230 HMMPfam hit to PF00515, Tetratricopeptide repeat, score 1.7e-06; HMMPfam hit to PF07719, Tetratricopeptide repeat, score 3.4e-05; HMMSmart hit to SM00028, no description, score 0.00024 291112016231 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 0.0025; HMMPfam hit to PF00515, Tetratricopeptide repeat, score 0.00056; HMMSmart hit to SM00028, no description, score 0.015 291112016232 polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824 291112016233 Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363 291112016234 RNase E interface [polypeptide binding]; other site 291112016235 trimer interface [polypeptide binding]; other site 291112016236 Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726 291112016237 Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364 291112016238 RNase E interface [polypeptide binding]; other site 291112016239 trimer interface [polypeptide binding]; other site 291112016240 active site 291112016241 Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393 291112016242 putative nucleic acid binding region [nucleotide binding]; other site 291112016243 G-X-X-G motif; other site 291112016244 S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472 291112016245 RNA binding site [nucleotide binding]; other site 291112016246 domain interface; other site 291112016247 HMMPfam hit to PF00575, S1 RNA binding domain, score 2.1e-27 291112016248 HMMSmart hit to SM00316, no description, score 2e-27 291112016249 HMMSmart hit to SM00322, no description, score 1.5e-12 291112016250 HMMPfam hit to PF00013, KH domain, score 3.8e-16 291112016251 HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 3.8e-21 291112016252 HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 2.1e-55 291112016253 HMMPfam hit to PF03726, Polyribonucleotide nucleotidyltransferase,, score 2.2e-37 291112016254 HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 5.9e-19 291112016255 HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 2.9e-45 291112016256 Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353 291112016257 16S/18S rRNA binding site [nucleotide binding]; other site 291112016258 S13e-L30e interaction site [polypeptide binding]; other site 291112016259 25S rRNA binding site [nucleotide binding]; other site 291112016260 HMMPfam hit to PF00312, Ribosomal protein S15, score 7.7e-45 291112016261 tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033 291112016262 Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573 291112016263 RNA binding site [nucleotide binding]; other site 291112016264 active site 291112016265 Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157 291112016266 HMMPfam hit to PF01509, TruB family pseudouridylate synthase (N term, score 1.9e-85 291112016267 ribosome-binding factor A; Validated; Region: rbfA; PRK00521 291112016268 HMMPfam hit to PF02033, Ribosome-binding factor A, score 1e-53 291112016269 Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760 291112016270 Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364 291112016271 translation initiation factor IF-2; Region: IF-2; TIGR00487 291112016272 Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760 291112016273 Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887 291112016274 G1 box; other site 291112016275 putative GEF interaction site [polypeptide binding]; other site 291112016276 GTP/Mg2+ binding site [chemical binding]; other site 291112016277 Switch I region; other site 291112016278 G2 box; other site 291112016279 G3 box; other site 291112016280 Switch II region; other site 291112016281 G4 box; other site 291112016282 G5 box; other site 291112016283 This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702 291112016284 Translation-initiation factor 2; Region: IF-2; pfam11987 291112016285 mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692 291112016286 HMMPfam hit to PF03144, Elongation factor Tu domain, score 4.7e-11 291112016287 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.2e-11 291112016288 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 6.4e-57 291112016289 HMMPfam hit to PF01926, GTPase of unknown function, score 9.2e-07 291112016290 HMMPfam hit to PF04760, Translation initiation factor IF-2, N-ter, score 5e-21 291112016291 HMMPfam hit to PF08364, Bacterial translation initiation factor I, score 6.9e-21 291112016292 HMMPfam hit to PF04760, Translation initiation factor IF-2, N-ter, score 1.4e-08 291112016293 transcription elongation factor NusA; Validated; Region: nusA; PRK09202 291112016294 NusA N-terminal domain; Region: NusA_N; pfam08529 291112016295 S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455 291112016296 RNA binding site [nucleotide binding]; other site 291112016297 homodimer interface [polypeptide binding]; other site 291112016298 NusA-like KH domain; Region: KH_5; pfam13184 291112016299 NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134 291112016300 G-X-X-G motif; other site 291112016301 transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954 291112016302 transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954 291112016303 HMMSmart hit to SM00316, no description, score 6.6e-07 291112016304 HMMPfam hit to PF00575, S1 RNA binding domain, score 1.4e-11 291112016305 HMMPfam hit to PF08529, NusA N-terminal domain, score 3.8e-67 291112016306 ribosome maturation protein RimP; Reviewed; Region: PRK00092 291112016307 Sm and related proteins; Region: Sm_like; cl00259 291112016308 Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734 291112016309 putative oligomer interface [polypeptide binding]; other site 291112016310 putative RNA binding site [nucleotide binding]; other site 291112016311 HMMPfam hit to PF02576, Uncharacterised BCR, YhbC family COG0779, score 9.2e-67 291112016312 Preprotein translocase SecG subunit; Region: SecG; pfam03840 291112016313 HMMPfam hit to PF03840, Preprotein translocase SecG subunit, score 1.7e-33 291112016314 2 probable transmembrane helices predicted for PAT2882 by TMHMM2.0 at aa 5-22 and 51-73 291112016315 phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887 291112016316 GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802 291112016317 active site 291112016318 substrate binding site [chemical binding]; other site 291112016319 metal binding site [ion binding]; metal-binding site 291112016320 HMMPfam hit to PF00408, Phosphoglucomutase/phosphomannomutase, C-, score 1e-06 291112016321 HMMPfam hit to PF02880, Phosphoglucomutase/phosphomannomutase, al, score 9.6e-41 291112016322 HMMPfam hit to PF02879, Phosphoglucomutase/phosphomannomutase, al, score 3.5e-45 291112016323 HMMPfam hit to PF02878, Phosphoglucomutase/phosphomannomutase, al, score 2.1e-59 291112016324 DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739 291112016325 dihydropteroate synthase; Region: DHPS; TIGR01496 291112016326 substrate binding pocket [chemical binding]; other site 291112016327 dimer interface [polypeptide binding]; other site 291112016328 inhibitor binding site; inhibition site 291112016329 HMMPfam hit to PF00809, Pterin binding enzyme, score 5.4e-101 291112016330 ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733 291112016331 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112016332 Walker A motif; other site 291112016333 ATP binding site [chemical binding]; other site 291112016334 Walker B motif; other site 291112016335 arginine finger; other site 291112016336 Peptidase family M41; Region: Peptidase_M41; pfam01434 291112016337 HMMPfam hit to PF01434, Peptidase family M41, score 1.5e-129 291112016338 HMMPfam hit to PF00004, ATPase family associated with various c, score 7.6e-100 291112016339 HMMSmart hit to SM00382, no description, score 1.9e-26 291112016340 HMMPfam hit to PF07728, ATPase family associated with various c, score 0.00015 291112016341 HMMPfam hit to PF06480, FtsH Extracellular, score 4.2e-49 291112016342 2 probable transmembrane helices predicted for PAT2885 by TMHMM2.0 at aa 7-26 and 100-122 291112016343 23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293 291112016344 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112016345 S-adenosylmethionine binding site [chemical binding]; other site 291112016346 HMMPfam hit to PF01728, FtsJ-like methyltransferase, score 8e-81 291112016347 CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; cl00663 291112016348 HMMPfam hit to PF01985, CRS1 / YhbY domain, score 5.4e-36 291112016349 transcription elongation factor GreA; Reviewed; Region: greA; PRK00226 291112016350 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 291112016351 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 291112016352 HMMPfam hit to PF01272, Prokaryotic transcription elongation fact, score 3.4e-43 291112016353 HMMPfam hit to PF03449, Prokaryotic transcription elongation fact, score 4.9e-48 291112016354 D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113 291112016355 D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666 291112016356 HMMPfam hit to PF02113, D-Ala-D-Ala carboxypeptidase 3 (S13) fa, score 2.1e-179 291112016357 GTPase CgtA; Reviewed; Region: obgE; PRK12298 291112016358 GTP1/OBG; Region: GTP1_OBG; pfam01018 291112016359 Obg GTPase; Region: Obg; cd01898 291112016360 G1 box; other site 291112016361 GTP/Mg2+ binding site [chemical binding]; other site 291112016362 Switch I region; other site 291112016363 G2 box; other site 291112016364 G3 box; other site 291112016365 Switch II region; other site 291112016366 G4 box; other site 291112016367 G5 box; other site 291112016368 HMMPfam hit to PF01926, GTPase of unknown function, score 6e-37 291112016369 HMMPfam hit to PF01018, GTP1/OBG, score 8e-95 291112016370 50S ribosomal protein L27; Validated; Region: rpmA; PRK05435 291112016371 HMMPfam hit to PF01016, Ribosomal L27 protein, score 7.5e-58 291112016372 50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278 291112016373 50S ribosomal protein L21; Validated; Region: rplU; PRK05573 291112016374 HMMPfam hit to PF00829, Ribosomal prokaryotic L21 protein, score 3.1e-60 291112016375 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142 291112016376 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 291112016377 substrate binding pocket [chemical binding]; other site 291112016378 chain length determination region; other site 291112016379 substrate-Mg2+ binding site; other site 291112016380 catalytic residues [active] 291112016381 aspartate-rich region 1; other site 291112016382 active site lid residues [active] 291112016383 aspartate-rich region 2; other site 291112016384 HMMPfam hit to PF00348, Polyprenyl synthetase, score 1.8e-116 291112016385 Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316 291112016386 Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316 291112016387 Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693 291112016388 malate dehydrogenase; Provisional; Region: PRK05086 291112016389 Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337 291112016390 NAD binding site [chemical binding]; other site 291112016391 dimerization interface [polypeptide binding]; other site 291112016392 Substrate binding site [chemical binding]; other site 291112016393 HMMPfam hit to PF02866, lactate/malate dehydrogenase, alpha/beta C-t, score 2.8e-71 291112016394 HMMPfam hit to PF00056, lactate/malate dehydrogenase, NAD binding do, score 5.7e-70 291112016395 arginine repressor; Provisional; Region: PRK05066 291112016396 Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316 291112016397 Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863 291112016398 HMMPfam hit to PF01316, Arginine repressor, DNA binding domai, score 4.1e-31 291112016399 HMMPfam hit to PF02863, Arginine repressor, C-terminal domain, score 3.1e-24 291112016400 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081 291112016401 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 291112016402 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 291112016403 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 291112016404 HMMPfam hit to PF02875, Mur ligase family, glutamate ligase doma, score 2e-06 291112016405 HMMPfam hit to PF08245, Mur ligase middle domain, score 1.3e-08 291112016406 HMMPfam hit to PF01225, Mur ligase family, catalytic domain, score 1.1e-24 291112016407 Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354 291112016408 AMP binding site [chemical binding]; other site 291112016409 metal binding site [ion binding]; metal-binding site 291112016410 active site 291112016411 HMMPfam hit to PF00316, Fructose-1-6-bisphosphatase, score 2.7e-210 291112016412 Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412 291112016413 dimer interface [polypeptide binding]; other site 291112016414 substrate binding site [chemical binding]; other site 291112016415 metal binding sites [ion binding]; metal-binding site 291112016416 HMMPfam hit to PF00719, Inorganic pyrophosphatase, score 2.8e-61 291112016417 GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661 291112016418 putative active site pocket [active] 291112016419 dimerization interface [polypeptide binding]; other site 291112016420 putative catalytic residue [active] 291112016421 HMMPfam hit to PF03674, Uncharacterised protein family (UPF0131), score 3.6e-29 291112016422 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911 291112016423 AsmA-like C-terminal region; Region: AsmA_2; pfam13502 291112016424 AsmA-like C-terminal region; Region: AsmA_2; pfam13502 291112016425 Family of unknown function (DUF490); Region: DUF490; pfam04357 291112016426 HMMPfam hit to PF04357, Family of unknown function (DUF490), score 1.7e-149 291112016427 1 probable transmembrane helix predicted for PAT2904 by TMHMM2.0 at aa 7-29 291112016428 Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729 291112016429 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 291112016430 Surface antigen; Region: Bac_surface_Ag; pfam01103 291112016431 HMMPfam hit to PF01103, Surface antigen, score 2e-71 291112016432 HMMPfam hit to PF07244, Surface antigen variable number repeat, score 1.4e-07 291112016433 methionine sulfoxide reductase A; Provisional; Region: PRK00058 291112016434 HMMPfam hit to PF01625, Peptide methionine sulfoxide reductase, score 1.8e-94 291112016435 Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253 291112016436 Domain of unknown function DUF21; Region: DUF21; pfam01595 291112016437 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 291112016438 Transporter associated domain; Region: CorC_HlyC; smart01091 291112016439 HMMPfam hit to PF01595, Domain of unknown function DUF21, score 2.4e-62 291112016440 3 probable transmembrane helices predicted for PAT2907 by TMHMM2.0 at aa 5-27, 58-80 and 100-117 291112016441 HMMPfam hit to PF00571, CBS domain pair, score 1.6e-14 291112016442 HMMPfam hit to PF03471, Transporter associated domain, score 9.3e-22 291112016443 Protein of unknown function (DUF1107); Region: DUF1107; pfam06526 291112016444 HMMPfam hit to PF06526, Protein of unknown function (DUF1107), score 1.7e-37 291112016445 Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695 291112016446 CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638 291112016447 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483 291112016448 active site 291112016449 HMMPfam hit to PF00459, Inositol monophosphatase family, score 1.1e-65 291112016450 peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570 291112016451 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346 291112016452 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 291112016453 HMMPfam hit to PF00254, FKBP-type peptidyl-prolyl cis-trans isomeras, score 1.9e-43 291112016454 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 291112016455 DNA binding residues [nucleotide binding] 291112016456 HMMPfam hit to PF00196, Bacterial regulatory proteins, luxR family, score 2.5e-23; HMMSmart hit to SM00421, no description, score 3e-20 291112016457 HMMPfam hit to PF04967, HTH DNA binding domain, score 0.001 291112016458 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 291112016459 H+ Antiporter protein; Region: 2A0121; TIGR00900 291112016460 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112016461 putative substrate translocation pore; other site 291112016462 10 probable transmembrane helices predicted for PAT2914 by TMHMM2.0 at aa 7-29, 65-87, 94-116, 159-181, 214-236, 246-264, 271-293, 297-319, 339-361 and 365-387 291112016463 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.2e-15 291112016464 Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192 291112016465 Carbamoyltransferase; Region: CmcH_NodU; pfam02543 291112016466 HMMPfam hit to PF02543, Carbamoyltransferase, score 3.6e-113 291112016467 N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834 291112016468 Amidinotransferase; Region: Amidinotransf; cl12043 291112016469 HMMPfam hit to PF02274, Amidinotransferase, score 1.7e-12 291112016470 Arginosuccinate synthase; Region: Arginosuc_synth; cl17227 291112016471 HMMPfam hit to PF00764, Arginosuccinate synthase, score 5.1e-92 291112016472 Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031 291112016473 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 291112016474 dimer interface [polypeptide binding]; other site 291112016475 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112016476 catalytic residue [active] 291112016477 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 6.6e-85 291112016478 50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137 291112016479 Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281 291112016480 Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948 291112016481 HMMPfam hit to PF03948, Ribosomal protein L9, C-terminal domai, score 1.9e-42 291112016482 HMMPfam hit to PF01281, Ribosomal protein L9, N-terminal domai, score 3.4e-28 291112016483 30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391 291112016484 HMMPfam hit to PF01084, Ribosomal protein S18, score 1.3e-32 291112016485 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 291112016486 dimer interface [polypeptide binding]; other site 291112016487 ssDNA binding site [nucleotide binding]; other site 291112016488 tetramer (dimer of dimers) interface [polypeptide binding]; other site 291112016489 HMMPfam hit to PF00436, Single-strand binding protein family, score 1.8e-18 291112016490 30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453 291112016491 HMMPfam hit to PF01250, Ribosomal protein S6, score 1.3e-49 291112016492 23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181 291112016493 RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032 291112016494 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 291112016495 HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 1.9e-62 291112016496 HMMPfam hit to PF08032, RNA 2'-O ribose methyltransferase subs, score 8.5e-22 291112016497 exoribonuclease R; Provisional; Region: PRK11642 291112016498 Ribonuclease B OB domain; Region: OB_RNB; pfam08206 291112016499 S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927 291112016500 RNB domain; Region: RNB; pfam00773 291112016501 S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471 291112016502 RNA binding site [nucleotide binding]; other site 291112016503 HMMPfam hit to PF00575, S1 RNA binding domain, score 4.3e-19 291112016504 HMMSmart hit to SM00316, no description, score 2.1e-14 291112016505 HMMPfam hit to PF00773, RNB-like protein, score 1.3e-110 291112016506 HMMPfam hit to PF08206, Ribonuclease B OB domain, score 0.0052 291112016507 HMMSmart hit to SM00357, no description, score 1.7e-13 291112016508 HMMPfam hit to PF08206, Ribonuclease B OB domain, score 2.1e-28 291112016509 HMMPfam hit to PF08461, Ribonuclease R winged-helix domain, score 6.3e-28 291112016510 transcriptional repressor NsrR; Provisional; Region: PRK11014 291112016511 Predicted transcriptional regulator [Transcription]; Region: COG1959 291112016512 HMMPfam hit to PF02082, Transcriptional regulator, score 1.9e-43 291112016513 Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788 291112016514 Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108 291112016515 GDP-binding site [chemical binding]; other site 291112016516 ACT binding site; other site 291112016517 IMP binding site; other site 291112016518 HMMPfam hit to PF00709, Adenylosuccinate synthetase, score 9.5e-301 291112016519 FtsH protease regulator HflC; Provisional; Region: PRK11029 291112016520 Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405 291112016521 HMMPfam hit to PF01145, SPFH domain / Band, score 1.2e-59 291112016522 HMMSmart hit to SM00244, no description, score 3.7e-39 291112016523 1 probable transmembrane helix predicted for PAT2927 by TMHMM2.0 at aa 5-24 291112016524 FtsH protease regulator HflK; Provisional; Region: PRK10930 291112016525 Bacterial membrane protein N terminal; Region: HflK_N; pfam12221 291112016526 Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404 291112016527 HMMPfam hit to PF01145, SPFH domain / Band, score 1.2e-49 291112016528 HMMSmart hit to SM00244, no description, score 4.6e-40 291112016529 1 probable transmembrane helix predicted for PAT2928 by TMHMM2.0 at aa 71-93 291112016530 GTPase HflX; Provisional; Region: PRK11058 291112016531 GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167 291112016532 HflX GTPase family; Region: HflX; cd01878 291112016533 G1 box; other site 291112016534 GTP/Mg2+ binding site [chemical binding]; other site 291112016535 Switch I region; other site 291112016536 G2 box; other site 291112016537 G3 box; other site 291112016538 Switch II region; other site 291112016539 G4 box; other site 291112016540 G5 box; other site 291112016541 HMMPfam hit to PF01926, GTPase of unknown function, score 2.4e-37 291112016542 bacterial Hfq-like; Region: Hfq; cd01716 291112016543 hexamer interface [polypeptide binding]; other site 291112016544 Sm1 motif; other site 291112016545 RNA binding site [nucleotide binding]; other site 291112016546 Sm2 motif; other site 291112016547 HMMPfam hit to PF01423, LSM domain, score 1.2e-11 291112016548 tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324 291112016549 tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091 291112016550 HMMPfam hit to PF01715, IPP transferase, score 3.2e-155 291112016551 DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095 291112016552 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112016553 ATP binding site [chemical binding]; other site 291112016554 Mg2+ binding site [ion binding]; other site 291112016555 G-X-G motif; other site 291112016556 MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL. EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482 291112016557 ATP binding site [chemical binding]; other site 291112016558 MutL C terminal dimerisation domain; Region: MutL_C; pfam08676 291112016559 HMMPfam hit to PF01119, DNA mismatch repair protein, C-termina, score 1.6e-38 291112016560 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and, score 2.7e-08 291112016561 N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431 291112016562 AMIN domain; Region: AMIN; pfam11741 291112016563 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 291112016564 active site 291112016565 metal binding site [ion binding]; metal-binding site 291112016566 HMMPfam hit to PF01520, N-acetylmuramoyl-L-alanine amidase, score 3.7e-93 291112016567 HMMSmart hit to SM00646, no description, score 4.1e-67 291112016568 1 probable transmembrane helix predicted for PAT2933 by TMHMM2.0 at aa 21-43 291112016569 Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520 291112016570 HMMPfam hit to PF02367, Uncharacterised P-loop hydrolase UPF0079, score 3.5e-58 291112016571 epoxyqueuosine reductase; Region: TIGR00276 291112016572 Domain of unknown function (DUF1730); Region: DUF1730; pfam08331 291112016573 HMMPfam hit to PF08331, Domain of unknown function (DUF1730), score 4e-35 291112016574 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 0.00053 291112016575 DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135 291112016576 catalytic site [active] 291112016577 putative active site [active] 291112016578 putative substrate binding site [chemical binding]; other site 291112016579 dimer interface [polypeptide binding]; other site 291112016580 HMMSmart hit to SM00479, no description, score 1.5e-22 291112016581 HMMPfam hit to PF00929, Exonuclease, score 7.3e-36 291112016582 GTPase RsgA; Reviewed; Region: PRK12288 291112016583 S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927 291112016584 RNA binding site [nucleotide binding]; other site 291112016585 Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854 291112016586 GTPase/Zn-binding domain interface [polypeptide binding]; other site 291112016587 GTP/Mg2+ binding site [chemical binding]; other site 291112016588 G4 box; other site 291112016589 G5 box; other site 291112016590 G1 box; other site 291112016591 Switch I region; other site 291112016592 G2 box; other site 291112016593 G3 box; other site 291112016594 Switch II region; other site 291112016595 HMMPfam hit to PF03193, Protein of unknown function, DUF258, score 5.2e-156 291112016596 phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044 291112016597 HMMPfam hit to PF02666, Phosphatidylserine decarboxylase, score 3.2e-99 291112016598 putative mechanosensitive channel protein; Provisional; Region: PRK10929 291112016599 Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794 291112016600 Mechanosensitive ion channel; Region: MS_channel; pfam00924 291112016601 10 probable transmembrane helices predicted for PAT2941 by TMHMM2.0 at aa 480-502, 523-545, 555-577, 598-620, 630-650, 671-693, 698-720, 828-850, 875-897 and 904-926 291112016602 HMMPfam hit to PF00924, Mechanosensitive ion channel, score 5.7e-74 291112016603 PAAR motif; Region: PAAR_motif; pfam05488 291112016604 HMMPfam hit to PF05488, PAAR motif, score 5.7 291112016605 HMMPfam hit to PF05488, PAAR motif, score 1.1e-05 291112016606 Bacterial protein of unknown function (DUF879); Region: DUF879; cl15462 291112016607 HMMPfam hit to PF05947, Bacterial protein of unknown function (DUF87, score 2.2e-07 291112016608 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 291112016609 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 291112016610 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 291112016611 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733 291112016612 HMMPfam hit to PF04524, Protein of unknown function, DUF586, score 6.9e-38 291112016613 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 291112016614 PAAR motif; Region: PAAR_motif; pfam05488 291112016615 HMMPfam hit to PF05488, PAAR motif, score 0.13 291112016616 PAAR motif; Region: PAAR_motif; pfam05488 291112016617 HMMPfam hit to PF05488, PAAR motif, score 0.01 291112016618 PAAR motif; Region: PAAR_motif; pfam05488 291112016619 HMMPfam hit to PF05488, PAAR motif, score 0.13 291112016620 HMMPfam hit to PF05488, PAAR motif, score 0.00027 291112016621 Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604 291112016622 putative hydrolase; Provisional; Region: PRK10976 291112016623 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112016624 active site 291112016625 motif I; other site 291112016626 motif II; other site 291112016627 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112016628 HMMPfam hit to PF05116, Sucrose-6F-phosphate phosphohydrolase, score 0.00077 291112016629 HMMPfam hit to PF08282, haloacid dehalogenase-like hydrolase, score 4.8e-78 291112016630 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 0.00031 291112016631 lysophospholipase L2; Provisional; Region: PRK10749 291112016632 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 291112016633 HMMPfam hit to PF00561, alpha/beta hydrolase fold, score 2.7e-15 291112016634 ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057 291112016635 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112016636 ATP binding site [chemical binding]; other site 291112016637 putative Mg++ binding site [ion binding]; other site 291112016638 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112016639 nucleotide binding region [chemical binding]; other site 291112016640 ATP-binding site [chemical binding]; other site 291112016641 This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956 291112016642 HRDC domain; Region: HRDC; pfam00570 291112016643 HMMPfam hit to PF00570, HRDC domain, score 1.3e-23; HMMSmart hit to SM00341, no description, score 4.2e-19 291112016644 HMMSmart hit to SM00490, no description, score 2.1e-29 291112016645 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 1.5e-29 291112016646 HMMSmart hit to SM00487, no description, score 8.2e-33 291112016647 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 2.8e-34 291112016648 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 291112016649 CoenzymeA binding site [chemical binding]; other site 291112016650 subunit interaction site [polypeptide binding]; other site 291112016651 PHB binding site; other site 291112016652 HMMPfam hit to PF03061, Thioesterase superfamily, score 1.1e-11 291112016653 putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430 291112016654 10 probable transmembrane helices predicted for PAT2963 by TMHMM2.0 at aa 9-28, 38-60, 73-95, 99-121, 128-145, 150-167, 180-197, 212-231, 238-260 and 270-289 291112016655 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1e-14 291112016656 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112016657 Coenzyme A binding pocket [chemical binding]; other site 291112016658 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 6.4e-08 291112016659 Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598 291112016660 Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835 291112016661 Cl binding site [ion binding]; other site 291112016662 oligomer interface [polypeptide binding]; other site 291112016663 HMMPfam hit to PF01544, CorA-like Mg2+ transporter protein, score 3.2e-94 291112016664 2 probable transmembrane helices predicted for PAT2966 by TMHMM2.0 at aa 255-273 and 288-310 291112016665 DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773 291112016666 Part of AAA domain; Region: AAA_19; pfam13245 291112016667 Family description; Region: UvrD_C_2; pfam13538 291112016668 HMMPfam hit to PF00580, UvrD/REP helicase, score 1.2e-219 291112016669 flavin mononucleotide phosphatase; Provisional; Region: PRK10748 291112016670 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 291112016671 motif II; other site 291112016672 HMMPfam hit to PF00702, haloacid dehalogenase-like hydrolase, score 7.5e-22 291112016673 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236 291112016674 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112016675 active site 291112016676 DNA binding site [nucleotide binding] 291112016677 Int/Topo IB signature motif; other site 291112016678 HMMPfam hit to PF00589, Phage integrase family, score 3.2e-55 291112016679 HMMPfam hit to PF02899, Phage integrase, N-terminal SAM-like, score 5.8e-21 291112016680 hypothetical protein; Provisional; Region: PRK10963 291112016681 HMMPfam hit to PF04340, Protein of unknown function, DUF484, score 3.6e-76 291112016682 diaminopimelate epimerase; Provisional; Region: dapF; PRK00450 291112016683 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 291112016684 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 291112016685 HMMPfam hit to PF01678, Diaminopimelate epimerase, score 5.8e-47 291112016686 HMMPfam hit to PF01678, Diaminopimelate epimerase, score 2.2e-50 291112016687 Prokaryotic lipoprotein-attachment site; Region: LPAM_2; cl02361 291112016688 1 probable transmembrane helix predicted for PAT2972 by TMHMM2.0 at aa 7-29 291112016689 Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503 291112016690 putative iron binding site [ion binding]; other site 291112016691 HMMPfam hit to PF01491, Frataxin-like domain, score 1.7e-62 291112016692 adenylate cyclase; Provisional; Region: cyaA; PRK09450 291112016693 Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633 291112016694 Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295 291112016695 HMMPfam hit to PF01295, Adenylate cyclase, class-I, score 0 291112016696 porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072 291112016697 Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494 291112016698 domain interfaces; other site 291112016699 active site 291112016700 HMMPfam hit to PF01379, Porphobilinogen deaminase, dipyrometh, score 6.1e-136 291112016701 HMMPfam hit to PF03900, Porphobilinogen deaminase, C-terminal, score 1.6e-29 291112016702 uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928 291112016703 Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578 291112016704 active site 291112016705 HMMPfam hit to PF02602, Uroporphyrinogen-III synthase HemD, score 1.2e-32 291112016706 putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920 291112016707 Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959 291112016708 HMMPfam hit to PF04375, HemX, score 3.8e-142 291112016709 1 probable transmembrane helix predicted for PAT2977 by TMHMM2.0 at aa 37-59 291112016710 putative protoheme IX biogenesis protein; Provisional; Region: PRK10747 291112016711 HemY protein N-terminus; Region: HemY_N; pfam07219 291112016712 HMMPfam hit to PF07219, HemY protein N-terminus, score 1.1e-56 291112016713 2 probable transmembrane helices predicted for PAT2978 by TMHMM2.0 at aa 7-29 and 39-61 291112016714 HMMPfam hit to PF07719, Tetratricopeptide repeat, score 7.2e-05 291112016715 2 probable transmembrane helices predicted for PAT2979 by TMHMM2.0 at aa 36-56 and 66-88 291112016716 putative transport protein YifK; Provisional; Region: PRK10746 291112016717 HMMPfam hit to PF00324, Amino acid permease, score 2e-116 291112016718 12 probable transmembrane helices predicted for PAT2980 by TMHMM2.0 at aa 21-40, 45-64, 98-120, 130-152, 159-181, 196-218, 245-267, 282-304, 336-358, 363-385, 406-428 and 434-456 291112016719 Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922 291112016720 The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533 291112016721 HMMPfam hit to PF03808, Glycosyl transferase WecB/TagA/CpsF f, score 6.9e-84 291112016722 putative common antigen polymerase; Provisional; Region: PRK02975 291112016723 HMMPfam hit to PF06899, WzyE protein, score 0 291112016724 11 probable transmembrane helices predicted for PAT2982 by TMHMM2.0 at aa 6-25, 38-60, 70-89, 110-132, 152-174, 181-200, 204-223, 225-244, 337-359, 380-397 and 407-429 291112016725 4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429 291112016726 HMMPfam hit to PF07429, 4-alpha-L-fucosyltransferase (Fuc4NAc, score 6.2e-211 291112016727 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 291112016728 Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125 291112016729 12 probable transmembrane helices predicted for PAT2984 by TMHMM2.0 at aa 13-35, 45-67, 79-101, 116-138, 150-172, 176-195, 216-238, 253-275, 296-318, 333-355, 362-384 and 394-412 291112016730 HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 6.5e-07 291112016731 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 291112016732 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 291112016733 inhibitor-cofactor binding pocket; inhibition site 291112016734 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112016735 catalytic residue [active] 291112016736 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 1.7e-81 291112016737 HMMPfam hit to PF00155, Aminotransferase class I and II, score 5.6e-05 291112016738 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0012 291112016739 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 291112016740 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 291112016741 Coenzyme A binding pocket [chemical binding]; other site 291112016742 HMMPfam hit to PF00583, Acetyltransferase (GNAT) family, score 1.4e-11 291112016743 G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538 291112016744 glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207 291112016745 substrate binding site; other site 291112016746 tetramer interface; other site 291112016747 HMMPfam hit to PF00483, Nucleotidyl transferase, score 4.6e-111 291112016748 dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217 291112016749 dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246 291112016750 NAD binding site [chemical binding]; other site 291112016751 substrate binding site [chemical binding]; other site 291112016752 homodimer interface [polypeptide binding]; other site 291112016753 active site 291112016754 HMMPfam hit to PF04321, RmlD substrate binding domain, score 5.7e-07 291112016755 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 3.9e-08 291112016756 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 2.2e-05 291112016757 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 9.8e-99 291112016758 HMMPfam hit to PF07993, Male sterility protein, score 2.8e-08 291112016759 UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064 291112016760 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 291112016761 UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984 291112016762 HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 7.2e-27 291112016763 HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 4.2e-43 291112016764 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 2.9e-88 291112016765 UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381 291112016766 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 291112016767 active site 291112016768 homodimer interface [polypeptide binding]; other site 291112016769 HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 1.4e-195 291112016770 lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638 291112016771 Chain length determinant protein; Region: Wzz; cl15801 291112016772 2 probable transmembrane helices predicted for PAT2991 by TMHMM2.0 at aa 33-52 and 327-346 291112016773 HMMPfam hit to PF02706, Chain length determinant protein, score 5.2e-10 291112016774 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119 291112016775 This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853 291112016776 Mg++ binding site [ion binding]; other site 291112016777 putative catalytic motif [active] 291112016778 substrate binding site [chemical binding]; other site 291112016779 11 probable transmembrane helices predicted for PAT2992 by TMHMM2.0 at aa 5-24, 45-67, 72-89, 102-124, 134-153, 160-179, 184-206, 213-232, 242-261, 294-311 and 321-338 291112016780 HMMPfam hit to PF00953, Glycosyl transferase family, score 6.2e-10 291112016781 transcription termination factor Rho; Provisional; Region: rho; PRK09376 291112016782 Rho termination factor, N-terminal domain; Region: Rho_N; smart00959 291112016783 Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459 291112016784 RNA binding site [nucleotide binding]; other site 291112016785 Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128 291112016786 multimer interface [polypeptide binding]; other site 291112016787 Walker A motif; other site 291112016788 ATP binding site [chemical binding]; other site 291112016789 Walker B motif; other site 291112016790 HMMPfam hit to PF00006, ATP synthase alpha/beta family, nucleoti, score 1.7e-78 291112016791 HMMSmart hit to SM00382, no description, score 3.8e-08 291112016792 HMMPfam hit to PF07497, Rho termination factor, RNA-binding doma, score 3.7e-59 291112016793 HMMSmart hit to SM00357, no description, score 9.6e-19 291112016794 HMMPfam hit to PF08206, Ribonuclease B OB domain, score 0.0011 291112016795 HMMPfam hit to PF07498, Rho termination factor, N-terminal domai, score 1e-19 291112016796 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 291112016797 Thioredoxin-like; Region: Thioredoxin_8; pfam13905 291112016798 catalytic residues [active] 291112016799 HMMPfam hit to PF00085, Thioredoxin, score 1.1e-53 291112016800 ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837 291112016801 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 291112016802 ATP binding site [chemical binding]; other site 291112016803 Mg++ binding site [ion binding]; other site 291112016804 motif III; other site 291112016805 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 291112016806 nucleotide binding region [chemical binding]; other site 291112016807 ATP-binding site [chemical binding]; other site 291112016808 HMMSmart hit to SM00487, no description, score 3.9e-52 291112016809 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 1e-56 291112016810 HMMSmart hit to SM00490, no description, score 3.1e-31 291112016811 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 2.7e-33 291112016812 guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031 291112016813 Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541 291112016814 HMMPfam hit to PF02541, Ppx/GppA phosphatase family, score 3.1e-113 291112016815 ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919 291112016816 Part of AAA domain; Region: AAA_19; pfam13245 291112016817 Family description; Region: UvrD_C_2; pfam13538 291112016818 HMMPfam hit to PF00580, UvrD/REP helicase, score 2.9e-218 291112016819 ketol-acid reductoisomerase; Validated; Region: PRK05225 291112016820 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991 291112016821 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450 291112016822 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450 291112016823 HMMPfam hit to PF01450, Acetohydroxy acid isomeroreductase, catalyti, score 4.1e-133 291112016824 HMMPfam hit to PF07991, Acetohydroxy acid isomeroreductase, catalyti, score 5.5e-85 291112016825 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112016826 DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716 291112016827 The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430 291112016828 putative dimerization interface [polypeptide binding]; other site 291112016829 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 4.6e-19 291112016830 HMMPfam hit to PF03466, LysR substrate binding domain, score 2.5e-30 291112016831 Helix-turn-helix domain; Region: HTH_18; pfam12833 291112016832 HMMSmart hit to SM00342, no description, score 1.3e-10 291112016833 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 291112016834 flavin-dependent oxidoreductase, MSMEG_0569 family; Region: MSMEG_0569_nitr; TIGR04046 291112016835 HMMPfam hit to PF01266, FAD dependent oxidoreductase, score 5e-05 291112016836 Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443 291112016837 HMMPfam hit to PF04443, Acyl-protein synthetase, LuxE, score 3.9e-28 291112016838 Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664 291112016839 trimerization site [polypeptide binding]; other site 291112016840 active site 291112016841 HMMPfam hit to PF01592, NifU-like N terminal domain, score 2e-08 291112016842 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104 291112016843 cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402 291112016844 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112016845 catalytic residue [active] 291112016846 HMMPfam hit to PF00266, Aminotransferase class-V, score 1.1e-52 291112016847 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0014 291112016848 Phosphopantetheine attachment site; Region: PP-binding; cl09936 291112016849 beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150 291112016850 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 291112016851 dimer interface [polypeptide binding]; other site 291112016852 active site 291112016853 HMMPfam hit to PF00109, Beta-ketoacyl synthase, N-terminal do, score 2.2e-27 291112016854 HMMPfam hit to PF02801, Beta-ketoacyl synthase, C-terminal do, score 3.1e-58 291112016855 The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509 291112016856 HMMPfam hit to PF01575, MaoC like domain, score 0.0011 291112016857 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 291112016858 3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830 291112016859 NAD(P) binding site [chemical binding]; other site 291112016860 active site 291112016861 HMMPfam hit to PF00106, short chain dehydrogenase, score 1.9e-26 291112016862 multidrug efflux system protein EmrA; Provisional; Region: PRK15136 291112016863 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 291112016864 HlyD family secretion protein; Region: HlyD_3; pfam13437 291112016865 1 probable transmembrane helix predicted for PAT3009 by TMHMM2.0 at aa 21-43 291112016866 HMMPfam hit to PF00529, HlyD family secretion protein, score 1.1e-68 291112016867 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 291112016868 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112016869 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112016870 12 probable transmembrane helices predicted for PAT3010 by TMHMM2.0 at aa 20-42, 55-77, 87-106, 144-166, 171-193, 205-224, 239-258, 274-296, 306-328, 340-359, 369-391 and 484-506 291112016871 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 3.6e-60 291112016872 threonine dehydratase; Reviewed; Region: PRK09224 291112016873 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 291112016874 tetramer interface [polypeptide binding]; other site 291112016875 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112016876 catalytic residue [active] 291112016877 First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906 291112016878 putative Ile/Val binding site [chemical binding]; other site 291112016879 Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907 291112016880 putative Ile/Val binding site [chemical binding]; other site 291112016881 HMMPfam hit to PF00585, C-terminal regulatory domain of Threon, score 3.7e-40 291112016882 HMMPfam hit to PF00585, C-terminal regulatory domain of Threon, score 2.7e-37 291112016883 HMMPfam hit to PF00291, Pyridoxal-phosphate dependent enzyme, score 6.2e-105 291112016884 dihydroxy-acid dehydratase; Provisional; Region: PRK12448 291112016885 HMMPfam hit to PF00920, Dehydratase family, score 0 291112016886 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115 291112016887 BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557 291112016888 homodimer interface [polypeptide binding]; other site 291112016889 substrate-cofactor binding pocket; other site 291112016890 catalytic residue [active] 291112016891 HMMPfam hit to PF01063, Aminotransferase class IV, score 1.4e-138 291112016892 acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152 291112016893 acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978 291112016894 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 291112016895 PYR/PP interface [polypeptide binding]; other site 291112016896 dimer interface [polypeptide binding]; other site 291112016897 TPP binding site [chemical binding]; other site 291112016898 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 291112016899 Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015 291112016900 TPP-binding site [chemical binding]; other site 291112016901 dimer interface [polypeptide binding]; other site 291112016902 HMMPfam hit to PF02775, Thiamine pyrophosphate enzyme, C-termina, score 7.5e-68 291112016903 HMMPfam hit to PF00205, Thiamine pyrophosphate enzyme, central d, score 5.1e-70 291112016904 HMMPfam hit to PF02776, Thiamine pyrophosphate enzyme, N-termina, score 4.5e-102 291112016905 putative ATP-dependent protease; Provisional; Region: PRK09862 291112016906 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 291112016907 Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078 291112016908 Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335 291112016909 HMMPfam hit to PF01078, Magnesium chelatase, subunit ChlI, score 5.2e-142 291112016910 HMMSmart hit to SM00382, no description, score 7.8e-10 291112016911 HMMPfam hit to PF07728, ATPase family associated with various ce, score 1.2e-05 291112016912 hypothetical protein; Provisional; Region: PRK11027 291112016913 HMMPfam hit to PF04219, Protein of unknown function, DUF, score 2.5e-46 291112016914 transcriptional regulator HdfR; Provisional; Region: PRK03601 291112016915 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112016916 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 291112016917 HMMPfam hit to PF01609, Transposase DDE domain, score 1.3e-19 291112016918 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663 291112016919 Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645 291112016920 trimer interface [polypeptide binding]; other site 291112016921 putative metal binding site [ion binding]; other site 291112016922 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.8 291112016923 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 26 291112016924 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 14 291112016925 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 2.8 291112016926 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 4.5 291112016927 shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258 291112016928 Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501 291112016929 NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065 291112016930 shikimate binding site; other site 291112016931 NAD(P) binding site [chemical binding]; other site 291112016932 HMMPfam hit to PF01488, Shikimate / quinate 5-dehydrogenase, score 1e-20 291112016933 HMMPfam hit to PF08501, Shikimate dehydrogenase substrate bind, score 1.5e-25 291112016934 tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634 291112016935 HMMPfam hit to PF01300, yrdC domain, score 1.5e-56 291112016936 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 291112016937 Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551 291112016938 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 291112016939 Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396 291112016940 HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 2.4e-13 291112016941 HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 3.2e-18 291112016942 HMMPfam hit to PF01396, Topoisomerase DNA binding C4 zinc fing, score 3.7e-09 291112016943 hypothetical protein; Provisional; Region: PRK10736 291112016944 DNA protecting protein DprA; Region: dprA; TIGR00732 291112016945 HMMPfam hit to PF02481, SMF family, score 1.8e-103 291112016946 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 291112016947 active site 291112016948 catalytic residues [active] 291112016949 metal binding site [ion binding]; metal-binding site 291112016950 HMMPfam hit to PF01327, Polypeptide deformylase, score 5.4e-82 291112016951 methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005 291112016952 Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646 291112016953 putative active site [active] 291112016954 substrate binding site [chemical binding]; other site 291112016955 putative cosubstrate binding site; other site 291112016956 catalytic site [active] 291112016957 C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704 291112016958 substrate binding site [chemical binding]; other site 291112016959 HMMPfam hit to PF00551, Formyl transferase, score 3e-70 291112016960 HMMPfam hit to PF02911, Formyl transferase, C-terminal domain, score 5.9e-46 291112016961 16S rRNA methyltransferase B; Provisional; Region: PRK10901 291112016962 RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223 291112016963 putative RNA binding site [nucleotide binding]; other site 291112016964 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112016965 S-adenosylmethionine binding site [chemical binding]; other site 291112016966 HMMPfam hit to PF01029, NusB family, score 1.5e-39 291112016967 HMMPfam hit to PF01189, NOL1/NOP2/sun family, score 2e-116 291112016968 potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496 291112016969 TrkA-N domain; Region: TrkA_N; pfam02254 291112016970 TrkA-C domain; Region: TrkA_C; pfam02080 291112016971 TrkA-N domain; Region: TrkA_N; pfam02254 291112016972 TrkA-C domain; Region: TrkA_C; pfam02080 291112016973 HMMPfam hit to PF02254, TrkA-N domain, score 3.2e-37 291112016974 HMMPfam hit to PF02080, TrkA-C domain, score 1.3e-12 291112016975 HMMPfam hit to PF02254, TrkA-N domain, score 1e-33 291112016976 HMMPfam hit to PF02080, TrkA-C domain, score 8e-14 291112016977 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112016978 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 291112016979 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112016980 HMMPfam hit to PF01609, Transposase DDE domain, score 2e-12 291112016981 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112016982 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112016983 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 291112016984 Transposase; Region: DEDD_Tnp_IS110; pfam01548 291112016985 HMMPfam hit to PF01548, Transposase, score 0.0017 291112016986 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 291112016987 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 291112016988 Homeodomain-like domain; Region: HTH_23; pfam13384 291112016989 Winged helix-turn helix; Region: HTH_29; pfam13551 291112016990 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036 291112016991 HMMPfam hit to PF03889, Domain of unknown function, score 4.2e-15 291112016992 zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514 291112016993 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 291112016994 HMMSmart hit to SM00422, no description, score 0.00053 291112016995 50S ribosomal protein L17; Validated; Region: rplQ; PRK05591 291112016996 HMMPfam hit to PF01196, Ribosomal protein L17, score 2.4e-66 291112016997 DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182 291112016998 N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928 291112016999 alphaNTD homodimer interface [polypeptide binding]; other site 291112017000 alphaNTD - beta interaction site [polypeptide binding]; other site 291112017001 alphaNTD - beta' interaction site [polypeptide binding]; other site 291112017002 Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118 291112017003 HMMPfam hit to PF03118, Bacterial RNA polymerase, alpha chain C, score 1.9e-35 291112017004 HMMSmart hit to SM00662, no description, score 8.3e-105 291112017005 HMMPfam hit to PF01193, RNA polymerase Rpb3/Rpb11 dimerisation, score 1.2e-23 291112017006 HMMPfam hit to PF01000, RNA polymerase Rpb3/RpoA insert domain, score 3.4e-57 291112017007 30S ribosomal protein S4; Validated; Region: rpsD; PRK05327 291112017008 Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163 291112017009 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 291112017010 RNA binding surface [nucleotide binding]; other site 291112017011 HMMSmart hit to SM00363, no description, score 4.7e-20 291112017012 HMMPfam hit to PF01479, S4 domain, score 4.7e-20 291112017013 HMMPfam hit to PF00163, Ribosomal protein S4/S9 N-terminal domai, score 1.3e-36 291112017014 30S ribosomal protein S11; Validated; Region: PRK05309 291112017015 HMMPfam hit to PF00411, Ribosomal protein S11, score 3e-76 291112017016 30S ribosomal protein S13; Validated; Region: rpsM; PRK05179 291112017017 30S ribosomal protein S13; Region: bact_S13; TIGR03631 291112017018 HMMPfam hit to PF00416, Ribosomal protein S13/S18, score 2.1e-60 291112017019 preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204 291112017020 SecY translocase; Region: SecY; pfam00344 291112017021 10 probable transmembrane helices predicted for PAT0702 by TMHMM2.0 at aa 22-44, 76-98, 119-138, 153-175, 182-204, 214-236, 274-296, 316-338, 369-391 and 401-423 291112017022 HMMPfam hit to PF00344, eubacterial secY protein, score 6.2e-211 291112017023 50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592 291112017024 HMMPfam hit to PF00256, Ribosomal protein L15, score 6.8e-10 291112017025 HMMPfam hit to PF01305, Ribosomal protein L15 amino terminal re, score 4e-57 291112017026 Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658 291112017027 23S rRNA binding site [nucleotide binding]; other site 291112017028 HMMPfam hit to PF00327, Ribosomal protein L30p/L7e, score 2e-25 291112017029 30S ribosomal protein S5; Validated; Region: rpsE; PRK00550 291112017030 Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333 291112017031 Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719 291112017032 HMMPfam hit to PF03719, Ribosomal protein S5, C-terminal domai, score 2.6e-39 291112017033 HMMPfam hit to PF00333, Ribosomal protein S5, N-terminal domai, score 7.2e-40 291112017034 Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432 291112017035 5S rRNA interface [nucleotide binding]; other site 291112017036 23S rRNA interface [nucleotide binding]; other site 291112017037 L5 interface [polypeptide binding]; other site 291112017038 HMMPfam hit to PF00861, Ribosomal L18p/L5e family, score 5.3e-53 291112017039 50S ribosomal protein L6; Validated; Region: rplF; PRK05498 291112017040 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 291112017041 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 291112017042 HMMPfam hit to PF00347, Ribosomal protein L6, score 1e-30 291112017043 HMMPfam hit to PF00347, Ribosomal protein L6, score 2.7e-21 291112017044 30S ribosomal protein S8; Validated; Region: rpsH; PRK00136 291112017045 HMMPfam hit to PF00410, Ribosomal protein S8, score 5.8e-71 291112017046 30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881 291112017047 HMMPfam hit to PF00253, Ribosomal protein S14p/S29e, score 8.7e-25 291112017048 50S ribosomal protein L5; Validated; Region: rplE; PRK00010 291112017049 Ribosomal protein L5; Region: Ribosomal_L5; pfam00281 291112017050 ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673 291112017051 HMMPfam hit to PF00673, ribosomal L5P family C-terminus, score 6e-60 291112017052 HMMPfam hit to PF00281, Ribosomal protein L5, score 9.8e-34 291112017053 50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004 291112017054 KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089 291112017055 RNA binding site [nucleotide binding]; other site 291112017056 HMMPfam hit to PF00467, KOW motif, score 1.3e-06 291112017057 HMMSmart hit to SM00739, no description, score 0.0012 291112017058 50S ribosomal protein L14; Validated; Region: rplN; PRK05483 291112017059 30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610 291112017060 Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433 291112017061 23S rRNA interface [nucleotide binding]; other site 291112017062 5S rRNA interface [nucleotide binding]; other site 291112017063 putative antibiotic binding site [chemical binding]; other site 291112017064 L25 interface [polypeptide binding]; other site 291112017065 L27 interface [polypeptide binding]; other site 291112017066 30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310 291112017067 K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3 is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH...; Region: 30S_S3_KH; cd02412 291112017068 G-X-X-G motif; other site 291112017069 Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189 291112017070 Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit. It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336 291112017071 protein-rRNA interface [nucleotide binding]; other site 291112017072 putative translocon binding site; other site 291112017073 30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357 291112017074 50S ribosomal protein L2; Validated; Region: rplB; PRK09374 291112017075 Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181 291112017076 Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947 291112017077 50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738 291112017078 50S ribosomal protein L4; Provisional; Region: rplD; PRK05319 291112017079 50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625 291112017080 HMMPfam hit to PF00297, Ribosomal protein L3, score 6.9e-77 291112017081 30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596 291112017082 HMMPfam hit to PF00338, Ribosomal protein S10p/S20e, score 5.7e-62 291112017083 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 291112017084 Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612 291112017085 HMMPfam hit to PF01609, Transposase DDE domain, score 7.9e-28 291112017086 Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193 291112017087 Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907 291112017088 heme binding site [chemical binding]; other site 291112017089 ferroxidase pore; other site 291112017090 ferroxidase diiron center [ion binding]; other site 291112017091 HMMPfam hit to PF00210, Ferritin-like domain, score 1.4e-50 291112017092 bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509 291112017093 HMMPfam hit to PF04324, BFD-like [2Fe-2S] binding domain, score 1.4e-16 291112017094 elongation factor Tu; Reviewed; Region: PRK00049 291112017095 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 291112017096 G1 box; other site 291112017097 GEF interaction site [polypeptide binding]; other site 291112017098 GTP/Mg2+ binding site [chemical binding]; other site 291112017099 Switch I region; other site 291112017100 G2 box; other site 291112017101 G3 box; other site 291112017102 Switch II region; other site 291112017103 G4 box; other site 291112017104 G5 box; other site 291112017105 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 291112017106 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 291112017107 Antibiotic Binding Site [chemical binding]; other site 291112017108 HMMPfam hit to PF03143, Elongation factor Tu C-terminal domain, score 1.4e-59 291112017109 HMMPfam hit to PF03144, Elongation factor Tu domain, score 2.9e-25 291112017110 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 1.1e-99 291112017111 Homeodomain-like domain; Region: HTH_23; pfam13384 291112017112 Winged helix-turn helix; Region: HTH_29; pfam13551 291112017113 Winged helix-turn helix; Region: HTH_33; pfam13592 291112017114 DDE superfamily endonuclease; Region: DDE_3; pfam13358 291112017115 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335 291112017116 pantothenate kinase; Provisional; Region: PRK05439 291112017117 Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025 291112017118 ATP-binding site [chemical binding]; other site 291112017119 CoA-binding site [chemical binding]; other site 291112017120 Mg2+-binding site [ion binding]; other site 291112017121 HMMPfam hit to PF00485, Phosphoribulokinase / Uridine kinase family, score 1.8e-07 291112017122 Biotin operon repressor [Transcription]; Region: BirA; COG1654 291112017123 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886 291112017124 Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099 291112017125 Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237 291112017126 HMMPfam hit to PF02237, Biotin protein ligase C terminal domain, score 1.1e-07 291112017127 HMMPfam hit to PF03099, Biotin/lipoate A/B protein ligase famil, score 8.3e-26 291112017128 HMMPfam hit to PF08279, HTH domain, score 6.9e-12 291112017129 UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046 291112017130 FAD binding domain; Region: FAD_binding_4; pfam01565 291112017131 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873 291112017132 HMMPfam hit to PF02873, UDP-N-acetylenolpyruvoylglucosamine red, score 2.4e-51 291112017133 HMMPfam hit to PF01565, FAD binding domain, score 2e-23 291112017134 glutamate racemase; Provisional; Region: PRK00865 291112017135 HMMPfam hit to PF01177, Asp/Glu/Hydantoin racemase, score 2.7e-89 291112017136 vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641 291112017137 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 291112017138 N-terminal plug; other site 291112017139 ligand-binding site [chemical binding]; other site 291112017140 HMMPfam hit to PF00593, TonB dependent receptor, score 3.8e-25 291112017141 HMMPfam hit to PF07715, TonB-dependent Receptor Plug Domain, score 1.8e-24 291112017142 tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031 291112017143 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112017144 S-adenosylmethionine binding site [chemical binding]; other site 291112017145 HMMPfam hit to PF05958, tRNA (Uracil-5-)-methyltransferase, score 5.2e-276 291112017146 hypothetical protein; Provisional; Region: PRK11056 291112017147 2 probable transmembrane helices predicted for PAT0713 by TMHMM2.0 at aa 7-26 and 31-49 291112017148 Region 9 291112017149 2 probable transmembrane helices predicted for PAT1857 by TMHMM2.0 at aa 16-35 and 39-58 291112017150 DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202 291112017151 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112017152 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 3.4e-11 291112017153 soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249 291112017154 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 291112017155 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852 291112017156 HMMPfam hit to PF07992, Pyridine nucleotide-disulphide oxidored, score 1.4e-40 291112017157 HMMPfam hit to PF00070, Pyridine nucleotide-disulphide oxidored, score 4.3e-28 291112017158 HMMPfam hit to PF02852, Pyridine nucleotide-disulphide oxidored, score 5.2e-38 291112017159 DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151 291112017160 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 291112017161 The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411 291112017162 dimerization interface [polypeptide binding]; other site 291112017163 HMMPfam hit to PF03466, LysR substrate binding domain, score 8e-53 291112017164 HMMPfam hit to PF00126, Bacterial regulatory helix-turn-helix, score 3.3e-21 291112017165 argininosuccinate lyase; Provisional; Region: PRK04833 291112017166 Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359 291112017167 active sites [active] 291112017168 tetramer interface [polypeptide binding]; other site 291112017169 HMMPfam hit to PF00206, Lyase, score 2.1e-126 291112017170 argininosuccinate synthase; Provisional; Region: PRK13820 291112017171 Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate . In...; Region: Argininosuccinate_Synthase; cd01999 291112017172 ANP binding site [chemical binding]; other site 291112017173 Substrate Binding Site II [chemical binding]; other site 291112017174 Substrate Binding Site I [chemical binding]; other site 291112017175 HMMPfam hit to PF00764, Arginosuccinate synthase, score 2.3e-170 291112017176 AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249 291112017177 nucleotide binding site [chemical binding]; other site 291112017178 N-acetyl-L-glutamate binding site [chemical binding]; other site 291112017179 HMMPfam hit to PF00696, Amino acid kinase family, score 2e-37 291112017180 N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436 291112017181 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 291112017182 HMMPfam hit to PF02774, Semialdehyde dehydrogenase, dimerisat, score 4.2e-31 291112017183 HMMPfam hit to PF01118, Semialdehyde dehydrogenase, NAD bindi, score 2.8e-55 291112017184 acetylornithine deacetylase; Provisional; Region: PRK05111 291112017185 M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894 291112017186 metal binding site [ion binding]; metal-binding site 291112017187 putative dimer interface [polypeptide binding]; other site 291112017188 HMMPfam hit to PF01546, Peptidase family M20/M25/M40, score 9.5e-43 291112017189 HMMPfam hit to PF07687, Peptidase dimerisation domain, score 5.4e-31 291112017190 phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009 291112017191 Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352 291112017192 HMMPfam hit to PF00311, Phosphoenolpyruvate carboxylase, score 2.2e-224 291112017193 Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537 291112017194 FAD binding site [chemical binding]; other site 291112017195 HMMPfam hit to PF02219, Methylenetetrahydrofolate reductase, score 3.4e-151 291112017196 bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466 291112017197 AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257 291112017198 putative catalytic residues [active] 291112017199 putative nucleotide binding site [chemical binding]; other site 291112017200 putative aspartate binding site [chemical binding]; other site 291112017201 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 291112017202 Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742 291112017203 HMMPfam hit to PF00742, Homoserine dehydrogenase, score 3.3e-97 291112017204 HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding d, score 1.1e-31 291112017205 HMMPfam hit to PF00696, Amino acid kinase family, score 2.8e-45 291112017206 cystathionine gamma-synthase; Provisional; Region: PRK08045 291112017207 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 291112017208 homodimer interface [polypeptide binding]; other site 291112017209 substrate-cofactor binding pocket; other site 291112017210 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112017211 catalytic residue [active] 291112017212 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 1.2e-203 291112017213 Met Repressor, MetJ. MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490 291112017214 dimerization interface [polypeptide binding]; other site 291112017215 DNA binding site [nucleotide binding] 291112017216 corepressor binding sites; other site 291112017217 HMMPfam hit to PF01340, Met Apo-repressor, MetJ, score 4e-85 291112017218 50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019 291112017219 HMMPfam hit to PF01197, Ribosomal protein L31, score 6.1e-44 291112017220 primosome assembly protein PriA; Validated; Region: PRK05580 291112017221 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 291112017222 ATP binding site [chemical binding]; other site 291112017223 putative Mg++ binding site [ion binding]; other site 291112017224 helicase superfamily c-terminal domain; Region: HELICc; smart00490 291112017225 ATP-binding site [chemical binding]; other site 291112017226 HMMSmart hit to SM00487, no description, score 5.9e-13 291112017227 HMMPfam hit to PF04851, Type III restriction enzyme, res subunit, score 3.8e-08 291112017228 HMMPfam hit to PF00270, DEAD/DEAH box helicase, score 7.4e-24 291112017229 HMMSmart hit to SM00490, no description, score 3.3e-07 291112017230 HMMPfam hit to PF00271, Helicase conserved C-terminal domain, score 0.00043 291112017231 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 291112017232 DNA binding site [nucleotide binding] 291112017233 DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041 291112017234 domain linker motif; other site 291112017235 Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284 291112017236 dimerization interface [polypeptide binding]; other site 291112017237 ligand binding site [chemical binding]; other site 291112017238 HMMSmart hit to SM00354, no description, score 1.6e-28 291112017239 HMMPfam hit to PF00356, Bacterial regulatory proteins, lacI fami, score 3e-11 291112017240 HMMPfam hit to PF00532, Periplasmic binding proteins and sugar b, score 8.7e-32 291112017241 Sporulation related domain; Region: SPOR; cl10051 291112017242 cell division protein FtsN; Provisional; Region: PRK12757 291112017243 1 probable transmembrane helix predicted for PAT1876 by TMHMM2.0 at aa 28-50 291112017244 HMMPfam hit to PF05036, Sporulation related domain, score 1.1e-15 291112017245 Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913 291112017246 active site 291112017247 HslU subunit interaction site [polypeptide binding]; other site 291112017248 HMMPfam hit to PF00227, Proteasome A-type and B-type, score 9.7e-36 291112017249 ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201 291112017250 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112017251 Walker A motif; other site 291112017252 ATP binding site [chemical binding]; other site 291112017253 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 291112017254 Walker B motif; other site 291112017255 arginine finger; other site 291112017256 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 291112017257 HMMSmart hit to SM00382, no description, score 3.7e-12 291112017258 HMMPfam hit to PF07724, ATPase family associated with various cellul, score 5.2e-53 291112017259 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080 291112017260 UbiA prenyltransferase family; Region: UbiA; pfam01040 291112017261 9 probable transmembrane helices predicted for PAT1879 by TMHMM2.0 at aa 21-40, 44-63, 102-119, 125-144, 149-171, 181-203, 228-246, 251-273 and 286-304 291112017262 HMMPfam hit to PF01040, UbiA prenyltransferase family, score 5.3e-37 291112017263 ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372 291112017264 HMMPfam hit to PF03737, Demethylmenaquinone methyltransferase, score 1.2e-75 291112017265 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3074 291112017266 HMMPfam hit to PF06005, Protein of unknown function (DUF904), score 2.4e-43 291112017267 Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333 291112017268 amphipathic channel; other site 291112017269 Asn-Pro-Ala signature motifs; other site 291112017270 HMMPfam hit to PF00230, Major intrinsic protein, score 3.3e-79 291112017271 6 probable transmembrane helices predicted for PAT1883 by TMHMM2.0 at aa 13-35, 45-67, 88-110, 146-168, 180-202 and 231-253 291112017272 glycerol kinase; Provisional; Region: glpK; PRK00047 291112017273 Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786 291112017274 N- and C-terminal domain interface [polypeptide binding]; other site 291112017275 active site 291112017276 MgATP binding site [chemical binding]; other site 291112017277 catalytic site [active] 291112017278 metal binding site [ion binding]; metal-binding site 291112017279 glycerol binding site [chemical binding]; other site 291112017280 homotetramer interface [polypeptide binding]; other site 291112017281 homodimer interface [polypeptide binding]; other site 291112017282 FBP binding site [chemical binding]; other site 291112017283 protein IIAGlc interface [polypeptide binding]; other site 291112017284 HMMPfam hit to PF00370, FGGY family of carbohydrate kinases, N-termi, score 1.2e-126 291112017285 HMMPfam hit to PF02782, FGGY family of carbohydrate kinases, C-termi, score 3.9e-104 291112017286 multidrug resistance protein D; Provisional; Region: emrD; PRK11652 291112017287 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112017288 putative substrate translocation pore; other site 291112017289 12 probable transmembrane helices predicted for PAT1885 by TMHMM2.0 at aa 12-34, 49-66, 78-97, 101-123, 135-157, 161-183, 204-226, 241-263, 276-298, 302-324, 331-353 and 368-387 291112017290 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 1.6e-43 291112017291 ferredoxin-NADP reductase; Provisional; Region: PRK10926 291112017292 Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195 291112017293 FAD binding pocket [chemical binding]; other site 291112017294 FAD binding motif [chemical binding]; other site 291112017295 phosphate binding motif [ion binding]; other site 291112017296 beta-alpha-beta structure motif; other site 291112017297 NAD binding pocket [chemical binding]; other site 291112017298 HMMPfam hit to PF00970, Oxidoreductase FAD-binding domain, score 3.2e-05 291112017299 HMMPfam hit to PF00175, Oxidoreductase NAD-binding domain, score 5.1e-17 291112017300 Predicted membrane protein [Function unknown]; Region: COG3152 291112017301 HMMPfam hit to PF05656, Protein of unknown function (DUF805), score 8.6e-36 291112017302 4 probable transmembrane helices predicted for PAT1887 by TMHMM2.0 at aa 19-41, 46-63, 75-97 and 101-120 291112017303 Protein of unknown function (DUF1454); Region: DUF1454; pfam07305 291112017304 HMMPfam hit to PF07305, Protein of unknown function (DUF1454), score 4e-57 291112017305 Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311 291112017306 triosephosphate isomerase; Provisional; Region: PRK14567 291112017307 substrate binding site [chemical binding]; other site 291112017308 dimer interface [polypeptide binding]; other site 291112017309 catalytic triad [active] 291112017310 HMMPfam hit to PF00121, Triosephosphate isomerase, score 6.1e-134 291112017311 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 291112017312 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 291112017313 substrate binding pocket [chemical binding]; other site 291112017314 membrane-bound complex binding site; other site 291112017315 hinge residues; other site 291112017316 HMMPfam hit to PF01547, Bacterial extracellular solute-binding prot, score 3.3e-08 291112017317 Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763 291112017318 6-phosphofructokinase; Region: PFKA_ATP; TIGR02482 291112017319 active site 291112017320 ADP/pyrophosphate binding site [chemical binding]; other site 291112017321 dimerization interface [polypeptide binding]; other site 291112017322 allosteric effector site; other site 291112017323 fructose-1,6-bisphosphate binding site; other site 291112017324 HMMPfam hit to PF00365, Phosphofructokinase, score 5.1e-179 291112017325 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589 291112017326 CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575 291112017327 HMMPfam hit to PF01148, Cytidylyltransferase family, score 1.3e-80 291112017328 8 probable transmembrane helices predicted for PAT1892 by TMHMM2.0 at aa 7-29, 49-71, 96-118, 122-139, 152-174, 184-203, 223-242 and 247-269 291112017329 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204 291112017330 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 291112017331 putative acyl-acceptor binding pocket; other site 291112017332 HMMSmart hit to SM00563, no description, score 4.3e-22 291112017333 HMMPfam hit to PF01553, Acyltransferase, score 8.1e-16 291112017334 Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558 291112017335 HMMPfam hit to PF01066, CDP-alcohol phosphatidyltransferase, score 0.002 291112017336 4 probable transmembrane helices predicted for PAT1894 by TMHMM2.0 at aa 35-57, 62-84, 113-145 and 184-206 291112017337 Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016 291112017338 HMMPfam hit to PF05016, Plasmid stabilisation system protein, score 3.4e-09 291112017339 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112017340 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112017341 non-specific DNA binding site [nucleotide binding]; other site 291112017342 salt bridge; other site 291112017343 sequence-specific DNA binding site [nucleotide binding]; other site 291112017344 HMMSmart hit to SM00530, no description, score 7.5e-11 291112017345 HMMPfam hit to PF01381, Helix-turn-helix, score 3.3e-08 291112017346 major tail tube protein; Provisional; Region: FII; PHA02600 291112017347 HMMPfam hit to PF04985, Phage tail tube protein FII, score 2.6e-103 291112017348 major tail sheath protein; Provisional; Region: FI; PHA02560 291112017349 HMMPfam hit to PF04984, Phage tail sheath protein, score 5.1e-175 291112017350 Phage-related protein [Function unknown]; Region: COG4679 291112017351 HMMPfam hit to PF05973, Phage derived protein Gp49-like (DUF891), score 2.8e-27 291112017352 Uncharacterized conserved small protein [Function unknown]; Region: COG5606 291112017353 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112017354 non-specific DNA binding site [nucleotide binding]; other site 291112017355 salt bridge; other site 291112017356 sequence-specific DNA binding site [nucleotide binding]; other site 291112017357 HMMSmart hit to SM00530, no description, score 1.1e-05 291112017358 HMMPfam hit to PF01381, Helix-turn-helix, score 5.3e-08 291112017359 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112017360 non-specific DNA binding site [nucleotide binding]; other site 291112017361 salt bridge; other site 291112017362 sequence-specific DNA binding site [nucleotide binding]; other site 291112017363 HMMSmart hit to SM00530, no description, score 8.3e-07 291112017364 HMMPfam hit to PF01381, Helix-turn-helix, score 1.5e-09 291112017365 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 291112017366 HMMPfam hit to PF02413, Caudovirales tail fibre assembly protein, score 1.2e-25 291112017367 Phage tail-collar fibre protein; Region: DUF3751; pfam12571 291112017368 Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406 291112017369 HMMPfam hit to PF03406, Phage tail fibre repeat, score 8.5e-13 291112017370 Phage tail-collar fibre protein; Region: DUF3751; pfam12571 291112017371 Phage tail protein (Tail_P2_I); Region: Tail_P2_I; cl01817 291112017372 Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684 291112017373 baseplate assembly protein; Provisional; Region: J; PHA02568 291112017374 HMMPfam hit to PF04865, Baseplate J-like protein, score 4.8e-91 291112017375 baseplate wedge subunit; Provisional; Region: W; PHA02516 291112017376 HMMPfam hit to PF04965, GPW / gp25 family, score 8.5e-45 291112017377 Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540 291112017378 phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644 291112017379 HMMPfam hit to PF04717, Phage-related baseplate assembly protein, score 8.5e-54 291112017380 Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069 291112017381 HMMPfam hit to PF05069, Phage virion morphogenesis family, score 4.1e-16 291112017382 P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891 291112017383 HMMPfam hit to PF06891, P2 phage tail completion protein R (GpR), score 1.4e-56 291112017384 1 probable transmembrane helix predicted for PAT1914 by TMHMM2.0 at aa 5-27 291112017385 virion protein; Provisional; Region: V; PHA02564 291112017386 Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106 291112017387 HMMPfam hit to PF05106, Phage holin family (Lysis protein S), score 1.5e-44 291112017388 1 probable transmembrane helix predicted for PAT1916 by TMHMM2.0 at aa 15-37 291112017389 Phage Tail Protein X; Region: Phage_tail_X; pfam05489 291112017390 HMMPfam hit to PF05489, Phage Tail Protein X, score 3.5e-08 291112017391 Phage head completion protein (GPL); Region: Phage_GPL; pfam05926 291112017392 HMMPfam hit to PF05926, Phage head completion protein (GPL), score 1.3e-58 291112017393 terminase endonuclease subunit; Provisional; Region: M; PHA02537 291112017394 Phage small terminase subunit; Region: Phage_term_smal; pfam05944 291112017395 HMMPfam hit to PF05944, Phage small terminase subunit, score 4.7e-73 291112017396 capsid protein; Provisional; Region: N; PHA02538 291112017397 HMMPfam hit to PF05125, Phage major capsid protein, P2 family, score 1e-192 291112017398 Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838 291112017399 HMMPfam hit to PF05929, Phage capsid scaffolding protein (GPO), score 2e-116 291112017400 terminase ATPase subunit; Provisional; Region: P; PHA02535 291112017401 Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056 291112017402 Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373 291112017403 HMMPfam hit to PF06056, Putative ATPase subunit of terminase (gpP, score 3.6e-31 291112017404 HMMPfam hit to PF03237, Terminase-like family, score 2.9e-169 291112017405 portal vertex protein; Provisional; Region: Q; PHA02536 291112017406 Phage portal protein; Region: Phage_portal; pfam04860 291112017407 HMMPfam hit to PF04860, Phage portal protein, score 4.1e-71 291112017408 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112017409 non-specific DNA binding site [nucleotide binding]; other site 291112017410 salt bridge; other site 291112017411 sequence-specific DNA binding site [nucleotide binding]; other site 291112017412 HMMSmart hit to SM00530, no description, score 9.8e-12 291112017413 HMMPfam hit to PF01381, Helix-turn-helix, score 1.1e-12 291112017414 Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973 291112017415 HMMPfam hit to PF05973, Phage derived protein Gp49-like (DUF891), score 2.3e-17 291112017416 Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315 291112017417 Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270 291112017418 Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315 291112017419 cofactor binding site; other site 291112017420 DNA binding site [nucleotide binding] 291112017421 substrate interaction site [chemical binding]; other site 291112017422 Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840 291112017423 HMMPfam hit to PF05840, Bacteriophage replication gene A protein (G, score 2.6e-94 291112017424 D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344 291112017425 HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA met, score 0.0019 291112017426 Regulatory phage protein cox; Region: Phage_Cox; pfam10743 291112017427 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 291112017428 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 291112017429 non-specific DNA binding site [nucleotide binding]; other site 291112017430 salt bridge; other site 291112017431 sequence-specific DNA binding site [nucleotide binding]; other site 291112017432 HMMSmart hit to SM00530, no description, score 0.00083 291112017433 integrase; Provisional; Region: int; PHA02601 291112017434 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 291112017435 active site 291112017436 Int/Topo IB signature motif; other site 291112017437 DNA binding site [nucleotide binding] 291112017438 HMMPfam hit to PF00589, Phage integrase family, score 3.1e-05 291112017439 CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916 291112017440 dimer interface [polypeptide binding]; other site 291112017441 DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955 291112017442 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 291112017443 active site 291112017444 intermolecular recognition site; other site 291112017445 dimerization interface [polypeptide binding]; other site 291112017446 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 291112017447 DNA binding site [nucleotide binding] 291112017448 HMMPfam hit to PF00072, Response regulator receiver domain, score 2e-39 291112017449 HMMSmart hit to SM00448, no description, score 3.6e-44 291112017450 HMMPfam hit to PF00486, Transcriptional regulatory protein, C te, score 2.6e-20 291112017451 two-component sensor protein; Provisional; Region: cpxA; PRK09470 291112017452 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054 291112017453 dimerization interface [polypeptide binding]; other site 291112017454 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 291112017455 dimer interface [polypeptide binding]; other site 291112017456 phosphorylation site [posttranslational modification] 291112017457 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 291112017458 ATP binding site [chemical binding]; other site 291112017459 Mg2+ binding site [ion binding]; other site 291112017460 G-X-G motif; other site 291112017461 2 probable transmembrane helices predicted for PAT1939 by TMHMM2.0 at aa 5-27 and 165-187 291112017462 HMMPfam hit to PF00672, HAMP domain, score 9.5e-13 291112017463 HMMSmart hit to SM00304, no description, score 5.8e-08 291112017464 HMMPfam hit to PF00512, His Kinase A (phosphoacceptor) domain, score 1.7e-18; HMMSmart hit to SM00388, no description, score 1.5e-16 291112017465 HMMSmart hit to SM00387, no description, score 8.8e-31 291112017466 HMMPfam hit to PF02518, Histidine kinase-, DNA gyrase B-, and HSP90, score 1.2e-36 291112017467 UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677 291112017468 prephenate dehydrogenase; Validated; Region: PRK08507 291112017469 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 291112017470 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720 291112017471 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 6.8e-66 291112017472 HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 6.9e-45 291112017473 HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 6e-18 291112017474 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 291112017475 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 291112017476 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 291112017477 HMMPfam hit to PF01408, Oxidoreductase family, NAD-binding Ros, score 8.1e-34 291112017478 HMMPfam hit to PF01113, Dihydrodipicolinate reductase, N-termi, score 0.00086 291112017479 HMMPfam hit to PF03447, Homoserine dehydrogenase, NAD binding, score 2.8e-05 291112017480 HMMPfam hit to PF02894, Oxidoreductase family, C-terminal alph, score 1.7e-14 291112017481 Bacterial transferase hexapeptide (six repeats); Region: Hexapep; pfam00132 291112017482 putative trimer interface [polypeptide binding]; other site 291112017483 WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358 291112017484 putative CoA binding site [chemical binding]; other site 291112017485 putative trimer interface [polypeptide binding]; other site 291112017486 putative active site [active] 291112017487 putative substrate binding site [chemical binding]; other site 291112017488 putative CoA binding site [chemical binding]; other site 291112017489 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.34 291112017490 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.014 291112017491 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.033 291112017492 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 22 291112017493 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 1.9 291112017494 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 291112017495 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 291112017496 inhibitor-cofactor binding pocket; inhibition site 291112017497 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112017498 catalytic residue [active] 291112017499 HMMPfam hit to PF00155, Aminotransferase class I and II, score 0.00013 291112017500 HMMPfam hit to PF01053, Cys/Met metabolism PLP-dependent enzy, score 0.0013 291112017501 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 1.2e-144 291112017502 HMMPfam hit to PF01212, Beta-eliminating lyase, score 1.8e-05 291112017503 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 291112017504 8 probable transmembrane helices predicted for PAT1944 by TMHMM2.0 at aa 9-31, 41-63, 76-98, 104-126, 147-169, 288-310, 322-344 and 375-397 291112017505 D-glucuronyl C5-epimerase C-terminus; Region: C5-epim_C; pfam06662 291112017506 2 probable transmembrane helices predicted for PAT1945 by TMHMM2.0 at aa 7-24 and 342-364 291112017507 10 probable transmembrane helices predicted for PAT1946 by TMHMM2.0 at aa 7-26, 36-58, 65-87, 92-111, 132-154, 174-196, 217-239, 249-271, 331-353 and 379-401 291112017508 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017509 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 291112017510 HMMPfam hit to PF00534, Glycosyl transferases group, score 2.6e-13 291112017511 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 291112017512 active site 291112017513 UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350 291112017514 homodimer interface [polypeptide binding]; other site 291112017515 HMMPfam hit to PF02350, UDP-N-acetylglucosamine 2-epimerase, score 3.2e-134 291112017516 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017517 This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794 291112017518 HMMPfam hit to PF00534, Glycosyl transferases group, score 0.00028 291112017519 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 291112017520 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 291112017521 inhibitor-cofactor binding pocket; inhibition site 291112017522 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112017523 catalytic residue [active] 291112017524 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 7.6e-174 291112017525 HMMPfam hit to PF01212, Beta-eliminating lyase, score 0.0015 291112017526 Bacterial sugar transferase; Region: Bac_transf; pfam02397 291112017527 HMMPfam hit to PF02397, Bacterial sugar transferase, score 2.3e-19 291112017528 1 probable transmembrane helix predicted for PAT1951 by TMHMM2.0 at aa 13-35 291112017529 Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086 291112017530 Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160 291112017531 UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237 291112017532 NAD(P) binding site [chemical binding]; other site 291112017533 homodimer interface [polypeptide binding]; other site 291112017534 substrate binding site [chemical binding]; other site 291112017535 active site 291112017536 4 probable transmembrane helices predicted for PAT1952 by TMHMM2.0 at aa 13-35, 50-69, 81-103 and 113-130 291112017537 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 3.9e-205 291112017538 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 8.4e-09 291112017539 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 0.0029 291112017540 HMMPfam hit to PF07993, Male sterility protein, score 0.002 291112017541 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 291112017542 EamA-like transporter family; Region: EamA; cl17759 291112017543 10 probable transmembrane helices predicted for PAT1954 by TMHMM2.0 at aa 13-32, 42-64, 85-104, 109-131, 138-155, 165-187, 207-229, 233-252, 265-282 and 287-309 291112017544 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 1.7e-10 291112017545 HMMPfam hit to PF00892, Integral membrane protein DUF6, score 0.001 291112017546 G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538 291112017547 glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207 291112017548 substrate binding site; other site 291112017549 tetramer interface; other site 291112017550 HMMPfam hit to PF00483, Nucleotidyl transferase, score 2.9e-109 291112017551 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399 291112017552 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 291112017553 inhibitor-cofactor binding pocket; inhibition site 291112017554 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112017555 catalytic residue [active] 291112017556 HMMPfam hit to PF01041, DegT/DnrJ/EryC1/StrS aminotransferase, score 5e-99 291112017557 WbqC-like protein family; Region: WbqC; pfam08889 291112017558 Formyltransferase, catalytic core domain; Region: FMT_core; cl00395 291112017559 active site 291112017560 substrate binding site [chemical binding]; other site 291112017561 cosubstrate binding site; other site 291112017562 catalytic site [active] 291112017563 HMMPfam hit to PF00551, Formyl transferase, score 4.8e-09 291112017564 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 291112017565 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 291112017566 HMMPfam hit to PF01943, Polysaccharide biosynthesis protein, score 5.7e-14 291112017567 14 probable transmembrane helices predicted for PAT1959 by TMHMM2.0 at aa 7-29, 39-61, 74-96, 111-133, 153-175, 179-201, 222-244, 259-276, 310-332, 342-364, 376-395, 405-422, 429-451 and 466-485 291112017568 Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647 291112017569 trimer interface [polypeptide binding]; other site 291112017570 active site 291112017571 substrate binding site [chemical binding]; other site 291112017572 CoA binding site [chemical binding]; other site 291112017573 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 62 291112017574 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 34 291112017575 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.18 291112017576 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 291112017577 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 291112017578 active site 291112017579 HMMPfam hit to PF00535, Glycosyl transferase family, score 6.2e-35 291112017580 Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045 291112017581 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 291112017582 trimer interface [polypeptide binding]; other site 291112017583 active site 291112017584 substrate binding site [chemical binding]; other site 291112017585 CoA binding site [chemical binding]; other site 291112017586 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.002 291112017587 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 12 291112017588 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 66 291112017589 8 probable transmembrane helices predicted for PAT1963 by TMHMM2.0 at aa 9-26, 46-68, 88-110, 125-147, 158-180, 190-212, 333-355 and 384-406 291112017590 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017591 This family is most closely related to the GT1 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis; Region: GT1_WbnK_like; cd03807 291112017592 putative ADP-binding pocket [chemical binding]; other site 291112017593 HMMPfam hit to PF00534, Glycosyl transferases group, score 3.6e-34 291112017594 Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a...; Region: AsnB; cd00712 291112017595 active site 291112017596 dimer interface [polypeptide binding]; other site 291112017597 Glutamine amidotransferase domain; Region: GATase_6; pfam13522 291112017598 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 291112017599 Ligand Binding Site [chemical binding]; other site 291112017600 Molecular Tunnel; other site 291112017601 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 291112017602 HMMPfam hit to PF00310, Glutamine amidotransferases class-II, score 4.3e-09 291112017603 HMMPfam hit to PF00733, Asparagine synthase, score 3e-104 291112017604 Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182 291112017605 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 291112017606 UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984 291112017607 HMMPfam hit to PF03721, UDP-glucose/GDP-mannose dehydrogenase, score 6.3e-62 291112017608 HMMPfam hit to PF00984, UDP-glucose/GDP-mannose dehydrogenase, score 7.6e-38 291112017609 HMMPfam hit to PF03720, UDP-glucose/GDP-mannose dehydrogenase, score 4.8e-17 291112017610 Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181 291112017611 UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256 291112017612 NAD binding site [chemical binding]; other site 291112017613 substrate binding site [chemical binding]; other site 291112017614 homodimer interface [polypeptide binding]; other site 291112017615 active site 291112017616 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.5e-69 291112017617 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 1.3e-09 291112017618 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 9.5e-05 291112017619 HMMPfam hit to PF07993, Male sterility protein, score 5.2e-05 291112017620 This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808 291112017621 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017622 putative ADP-binding pocket [chemical binding]; other site 291112017623 HMMPfam hit to PF00534, Glycosyl transferases group, score 6.1e-46 291112017624 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 291112017625 UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs; Region: UDP_G4E_4_SDR_e; cd05232 291112017626 putative NAD(P) binding site [chemical binding]; other site 291112017627 active site 291112017628 putative substrate binding site [chemical binding]; other site 291112017629 HMMPfam hit to PF04321, RmlD substrate binding domain, score 2.1e-07 291112017630 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 7e-20 291112017631 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 4.6e-12 291112017632 HMMPfam hit to PF07993, Male sterility protein, score 1.2e-09 291112017633 Bacterial sugar transferase; Region: Bac_transf; pfam02397 291112017634 HMMPfam hit to PF02397, Bacterial sugar transferase, score 1.6e-24 291112017635 1 probable transmembrane helix predicted for PAT1970 by TMHMM2.0 at aa 12-34 291112017636 Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086 291112017637 Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160 291112017638 UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237 291112017639 NAD(P) binding site [chemical binding]; other site 291112017640 homodimer interface [polypeptide binding]; other site 291112017641 substrate binding site [chemical binding]; other site 291112017642 active site 291112017643 4 probable transmembrane helices predicted for PAT1971 by TMHMM2.0 at aa 15-37, 50-72, 82-104 and 111-133 291112017644 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 4.2e-206 291112017645 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1.5e-07 291112017646 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 0.00049 291112017647 HMMPfam hit to PF07993, Male sterility protein, score 0.00063 291112017648 UDP-glucose 4-epimerase; Region: PLN02240 291112017649 UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247 291112017650 NAD binding site [chemical binding]; other site 291112017651 homodimer interface [polypeptide binding]; other site 291112017652 active site 291112017653 substrate binding site [chemical binding]; other site 291112017654 HMMPfam hit to PF02719, Polysaccharide biosynthesis protein, score 4.9e-06 291112017655 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase f, score 1e-83 291112017656 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/i, score 4.7e-09 291112017657 HMMPfam hit to PF07993, Male sterility protein, score 3.7e-06 291112017658 SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307 291112017659 HMMPfam hit to PF00588, SpoU rRNA Methylase family, score 9.6e-39 291112017660 serine acetyltransferase; Provisional; Region: cysE; PRK11132 291112017661 Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426 291112017662 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 291112017663 trimer interface [polypeptide binding]; other site 291112017664 active site 291112017665 substrate binding site [chemical binding]; other site 291112017666 CoA binding site [chemical binding]; other site 291112017667 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 0.45 291112017668 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 23 291112017669 HMMPfam hit to PF00132, Bacterial transferase hexapeptide (three rep, score 5.9 291112017670 HMMPfam hit to PF06426, Serine acetyltransferase, N-terminal, score 4.4e-58 291112017671 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094 291112017672 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 291112017673 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479 291112017674 HMMPfam hit to PF07479, NAD-dependent glycerol-3-phosphate deh, score 1.9e-80 291112017675 HMMPfam hit to PF01210, NAD-dependent glycerol-3-phosphate deh, score 5.9e-75 291112017676 HMMPfam hit to PF02558, Ketopantoate reductase PanE/ApbA, score 4.5e-05 291112017677 Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557 291112017678 SecA binding site; other site 291112017679 Preprotein binding site; other site 291112017680 HMMPfam hit to PF02556, Preprotein translocase subunit SecB, score 1.8e-92 291112017681 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 291112017682 active site residue [active] 291112017683 HMMSmart hit to SM00450, no description, score 5.5e-17 291112017684 HMMPfam hit to PF00581, Rhodanese-like domain, score 2.8e-13 291112017685 1 probable transmembrane helix predicted for PAT1977 by TMHMM2.0 at aa 5-24 291112017686 AmiB activator; Provisional; Region: PRK11637 291112017687 Peptidase family M23; Region: Peptidase_M23; pfam01551 291112017688 1 probable transmembrane helix predicted for PAT1978 by TMHMM2.0 at aa 27-49 291112017689 HMMPfam hit to PF01551, Peptidase family M23, score 4.3e-43 291112017690 Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936 291112017691 NodB motif; other site 291112017692 putative active site [active] 291112017693 putative catalytic site [active] 291112017694 Zn binding site [ion binding]; other site 291112017695 HMMPfam hit to PF04748, Divergent polysaccharide deacetylase, score 1e-100 291112017696 L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396 291112017697 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 291112017698 NAD(P) binding site [chemical binding]; other site 291112017699 HMMPfam hit to PF00107, Zinc-binding dehydrogenase, score 2.8e-39 291112017700 HMMPfam hit to PF08240, Alcohol dehydrogenase GroES-like domain, score 4.9e-44 291112017701 pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825 291112017702 KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454 291112017703 substrate-cofactor binding pocket; other site 291112017704 pyridoxal 5'-phosphate binding site [chemical binding]; other site 291112017705 catalytic residue [active] 291112017706 HMMPfam hit to PF00155, Aminotransferase class I and II, score 1.4e-112 291112017707 HMMPfam hit to PF00266, Aminotransferase class-V, score 0.00044 291112017708 ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248 291112017709 ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150 291112017710 NADP binding site [chemical binding]; other site 291112017711 homopentamer interface [polypeptide binding]; other site 291112017712 substrate binding site [chemical binding]; other site 291112017713 active site 291112017714 HMMPfam hit to PF04321, RmlD substrate binding domain, score 0.0028 291112017715 HMMPfam hit to PF01370, NAD dependent epimerase/dehydratase fam, score 8.2e-52 291112017716 HMMPfam hit to PF01073, 3-beta hydroxysteroid dehydrogenase/iso, score 5.3e-07 291112017717 HMMPfam hit to PF07993, Male sterility protein, score 0.0013 291112017718 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 291112017719 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 291112017720 putative active site [active] 291112017721 HMMPfam hit to PF01075, Glycosyltransferase family, score 2.2e-101 291112017722 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 291112017723 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 291112017724 putative active site [active] 291112017725 HMMPfam hit to PF01075, Glycosyltransferase family, score 2.4e-91 291112017726 Putative catalytic domain of lipopolysaccharide biosynthesis protein WalW and its bacterial homologs; Region: CE4_WalW; cd10935 291112017727 putative active site [active] 291112017728 putative catalytic site [active] 291112017729 lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422 291112017730 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 291112017731 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 291112017732 putative active site [active] 291112017733 HMMPfam hit to PF01075, Glycosyltransferase family, score 1.4e-35 291112017734 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017735 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 291112017736 HMMPfam hit to PF00534, Glycosyl transferases group, score 8.5e-27 291112017737 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017738 This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811 291112017739 putative ADP-binding pocket [chemical binding]; other site 291112017740 HMMPfam hit to PF00534, Glycosyl transferases group, score 6.6e-23 291112017741 3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749 291112017742 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413 291112017743 Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534 291112017744 HMMPfam hit to PF04413, 3-Deoxy-D-manno-octulosonic-acid tran, score 1.7e-97 291112017745 HMMPfam hit to PF00534, Glycosyl transferases group, score 4.7e-05 291112017746 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 291112017747 UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511 291112017748 putative metal binding site; other site 291112017749 HMMPfam hit to PF00535, Glycosyl transferase family, score 5.7e-16 291112017750 phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168 291112017751 Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163 291112017752 active site 291112017753 (T/H)XGH motif; other site 291112017754 HMMPfam hit to PF01467, Cytidylyltransferase, score 2.4e-28 291112017755 formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103 291112017756 N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966 291112017757 DNA binding site [nucleotide binding] 291112017758 catalytic residue [active] 291112017759 H2TH interface [polypeptide binding]; other site 291112017760 putative catalytic residues [active] 291112017761 turnover-facilitating residue; other site 291112017762 intercalation triad [nucleotide binding]; other site 291112017763 8OG recognition residue [nucleotide binding]; other site 291112017764 putative reading head residues; other site 291112017765 Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831 291112017766 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 291112017767 HMMPfam hit to PF06831, Formamidopyrimidine-DNA glycosylase H2, score 1.1e-46 291112017768 HMMPfam hit to PF01149, Formamidopyrimidine-DNA glycosylase N-, score 2.4e-55 291112017769 O-antigen ligase RfaL; Provisional; Region: PRK15487 291112017770 Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307 291112017771 11 probable transmembrane helices predicted for PAT1993 by TMHMM2.0 at aa 15-31, 38-57, 67-86, 98-115, 125-147, 164-182, 187-209, 211-228, 232-254, 325-347 and 362-384 291112017772 HMMPfam hit to PF04932, O-Antigen Polymerase, score 4.1e-16 291112017773 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017774 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 291112017775 HMMPfam hit to PF00534, Glycosyl transferases group, score 1.2e-15 291112017776 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017777 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 291112017778 HMMPfam hit to PF00534, Glycosyl transferases group, score 8e-47 291112017779 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859 291112017780 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 291112017781 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 291112017782 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 291112017783 HMMPfam hit to PF00534, Glycosyl transferases group, score 7.6e-43 291112017784 50S ribosomal protein L33; Validated; Region: rpmG; PRK00595 291112017785 HMMPfam hit to PF00471, Ribosomal protein L33, score 1.6e-21 291112017786 50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359 291112017787 HMMPfam hit to PF00830, Ribosomal L28 family, score 1.2e-35 291112017788 hypothetical protein; Reviewed; Region: PRK00024 291112017789 Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071 291112017790 MPN+ (JAMM) motif; other site 291112017791 Zinc-binding site [ion binding]; other site 291112017792 HMMPfam hit to PF04002, RadC, DNA repair protein, score 2.8e-70 291112017793 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579 291112017794 Flavoprotein; Region: Flavoprotein; pfam02441 291112017795 DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127 291112017796 HMMPfam hit to PF02441, Flavoprotein, score 1.1e-45 291112017797 HMMPfam hit to PF04127, DNA / pantothenate metabolism flavoprote, score 1.2e-34 291112017798 Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557 291112017799 trimer interface [polypeptide binding]; other site 291112017800 active site 291112017801 HMMPfam hit to PF00692, dUTPase, score 5.3e-51 291112017802 division inhibitor protein; Provisional; Region: slmA; PRK09480 291112017803 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 291112017804 HMMPfam hit to PF00440, Bacterial regulatory proteins, tetR family, score 2.3e-09 291112017805 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 291112017806 active site 291112017807 HMMPfam hit to PF00156, Phosphoribosyl transferase domain, score 4.6e-31 291112017808 ribonuclease PH; Reviewed; Region: rph; PRK00173 291112017809 Ribonuclease PH; Region: RNase_PH_bact; cd11362 291112017810 hexamer interface [polypeptide binding]; other site 291112017811 active site 291112017812 HMMPfam hit to PF03725, 3' exoribonuclease family, domain, score 1.1e-18 291112017813 HMMPfam hit to PF01138, 3' exoribonuclease family, domain, score 1.1e-56 291112017814 hypothetical protein; Provisional; Region: PRK11820 291112017815 YicC-like family, N-terminal region; Region: YicC_N; pfam03755 291112017816 Domain of unknown function (DUF1732); Region: DUF1732; pfam08340 291112017817 HMMPfam hit to PF03755, YicC-like family, N-terminal region, score 5.4e-75 291112017818 HMMPfam hit to PF08340, Domain of unknown function (DUF1732), score 6.3e-57 291112017819 Predicted transcriptional regulator [Transcription]; Region: COG2345 291112017820 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 291112017821 H+ Antiporter protein; Region: 2A0121; TIGR00900 291112017822 putative substrate translocation pore; other site 291112017823 HMMPfam hit to PF05977, Bacterial protein of unknown function (DUF89, score 0.00065 291112017824 12 probable transmembrane helices predicted for PAT2010 by TMHMM2.0 at aa 13-37, 47-69, 76-98, 105-127, 140-162, 172-194, 223-245, 255-277, 284-306, 310-332, 344-366 and 371-393 291112017825 HMMPfam hit to PF07690, Major Facilitator Superfamily, score 5.6e-30 291112017826 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524 291112017827 YegV-like sugar kinase. Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YegV_kinase_like; cd01944 291112017828 substrate binding site [chemical binding]; other site 291112017829 ATP binding site [chemical binding]; other site 291112017830 HMMPfam hit to PF00294, pfkB family carbohydrate kinase, score 4.3e-34 291112017831 Sulfatase; Region: Sulfatase; cl17466 291112017832 HMMPfam hit to PF00884, Sulfatase, score 5.3e-06 291112017833 5 probable transmembrane helices predicted for PAT2012 by TMHMM2.0 at aa 5-23, 28-47, 54-73, 101-123 and 135-157 291112017834 selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512 291112017835 SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171 291112017836 G1 box; other site 291112017837 putative GEF interaction site [polypeptide binding]; other site 291112017838 GTP/Mg2+ binding site [chemical binding]; other site 291112017839 Switch I region; other site 291112017840 G2 box; other site 291112017841 G3 box; other site 291112017842 Switch II region; other site 291112017843 G4 box; other site 291112017844 G5 box; other site 291112017845 selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696 291112017846 This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094 291112017847 Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106 291112017848 Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107 291112017849 HMMPfam hit to PF03144, Elongation factor Tu domain, score 1.5e-05 291112017850 HMMPfam hit to PF00009, Elongation factor Tu GTP binding domain, score 3.8e-28 291112017851 selenocysteine synthase; Provisional; Region: PRK04311 291112017852 Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390 291112017853 Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921 291112017854 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 291112017855 catalytic residue [active] 291112017856 HMMPfam hit to PF03841, L-seryl-tRNA selenium transferase, score 1.4e-232 291112017857 formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564 291112017858 formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562 291112017859 HMMPfam hit to PF04216, Protein involved in formate dehydrogenase fo, score 1.1e-168 291112017860 Methyltransferase domain; Region: Methyltransf_23; pfam13489 291112017861 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112017862 S-adenosylmethionine binding site [chemical binding]; other site 291112017863 HMMPfam hit to PF00891, O-methyltransferase, score 6.4e-21 291112017864 2 probable transmembrane helices predicted for PAT2017 by TMHMM2.0 at aa 12-34 and 54-76 291112017865 Methyltransferase domain; Region: Methyltransf_23; pfam13489 291112017866 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 291112017867 S-adenosylmethionine binding site [chemical binding]; other site 291112017868 HMMPfam hit to PF00891, O-methyltransferase, score 3.9e-30 291112017869 formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639 291112017870 formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583 291112017871 4 probable transmembrane helices predicted for PAT2019 by TMHMM2.0 at aa 21-40, 55-77, 115-137 and 152-174 291112017872 formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582 291112017873 Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163 291112017874 HMMPfam hit to PF00037, 4Fe-4S binding domain, score 2.5e-05 291112017875 formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553 291112017876 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752 291112017877 [4Fe-4S] binding site [ion binding]; other site 291112017878 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 291112017879 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752 291112017880 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792 291112017881 molybdopterin cofactor binding site; other site 291112017882 HMMPfam hit to PF01568, Molydopterin dinucleotide binding dom, score 6.7e-16 291112017883 HMMPfam hit to PF00384, Molybdopterin oxidoreductase, score 1.7e-09 291112017884 HMMPfam hit to PF04879, Molybdopterin oxidoreductase Fe4S4 dom, score 1.7e-22 291112017885 1 probable transmembrane helix predicted for PAT2022 by TMHMM2.0 at aa 17-39 291112017886 formate dehydrogenase accessory protein; Reviewed; Region: PRK00724 291112017887 HMMPfam hit to PF02634, FdhD/NarQ family, score 3.2e-117 291112017888 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 291112017889 Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338 291112017890 HMMPfam hit to PF02086, D12 class N6 adenine-specific DNA met, score 1.4e-06 291112017891 Restriction endonuclease NotI; Region: NotI; pfam12183 291112017892 tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291 291112017893 GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396 291112017894 trmE is a tRNA modification GTPase; Region: trmE; cd04164 291112017895 G1 box; other site 291112017896 GTP/Mg2+ binding site [chemical binding]; other site 291112017897 Switch I region; other site 291112017898 G2 box; other site 291112017899 Switch II region; other site 291112017900 G3 box; other site 291112017901 G4 box; other site 291112017902 G5 box; other site 291112017903 Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631 291112017904 HMMPfam hit to PF08477, Miro-like protein, score 4.2e-09; HMMPfam hit to PF01926, GTPase of unknown function, score 6.1e-42 291112017905 membrane protein insertase; Provisional; Region: PRK01318 291112017906 membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592 291112017907 HMMPfam hit to PF02096, 60Kd inner membrane protein, score 3.4e-119 291112017908 4 probable transmembrane helices predicted for PAT2029 by TMHMM2.0 at aa 7-24, 347-369, 416-438 and 494-516 291112017909 hypothetical protein; Validated; Region: PRK00041 291112017910 HMMPfam hit to PF01809, Domain of unknown function DUF37, score 1e-43 291112017911 ribonuclease P; Reviewed; Region: rnpA; PRK01732 291112017912 HMMPfam hit to PF00825, Ribonuclease P, score 1.1e-60 291112017913 50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399 291112017914 HMMPfam hit to PF00468, Ribosomal protein L34, score 2e-21