-- dump date   	20140619_234002
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
243265000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
243265000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
243265000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265000004	Walker A motif; other site
243265000005	ATP binding site [chemical binding]; other site
243265000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
243265000007	Walker B motif; other site
243265000008	arginine finger; other site
243265000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
243265000010	DnaA box-binding interface [nucleotide binding]; other site
243265000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
243265000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
243265000013	putative DNA binding surface [nucleotide binding]; other site
243265000014	dimer interface [polypeptide binding]; other site
243265000015	beta-clamp/clamp loader binding surface; other site
243265000016	beta-clamp/translesion DNA polymerase binding surface; other site
243265000017	recF protein; Region: recf; TIGR00611
243265000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265000019	Walker A/P-loop; other site
243265000020	ATP binding site [chemical binding]; other site
243265000021	Q-loop/lid; other site
243265000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265000023	ABC transporter signature motif; other site
243265000024	Walker B; other site
243265000025	D-loop; other site
243265000026	H-loop/switch region; other site
243265000027	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
243265000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265000029	Mg2+ binding site [ion binding]; other site
243265000030	G-X-G motif; other site
243265000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
243265000032	anchoring element; other site
243265000033	dimer interface [polypeptide binding]; other site
243265000034	ATP binding site [chemical binding]; other site
243265000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
243265000036	active site
243265000037	putative metal-binding site [ion binding]; other site
243265000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
243265000039	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265000040	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
243265000041	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
243265000042	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
243265000043	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
243265000044	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
243265000045	tail protein; Provisional; Region: D; PHA02561
243265000046	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
243265000047	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
243265000048	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
243265000049	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
243265000050	Phage tail tube protein FII; Region: Phage_tube; pfam04985
243265000051	major tail sheath protein; Provisional; Region: FI; PHA02560
243265000052	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265000053	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265000054	Phage Tail Collar Domain; Region: Collar; pfam07484
243265000055	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
243265000056	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265000057	Phage Tail Collar Domain; Region: Collar; pfam07484
243265000058	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
243265000059	Baseplate J-like protein; Region: Baseplate_J; cl01294
243265000060	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
243265000061	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
243265000062	Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812
243265000063	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
243265000064	Predicted transcriptional regulator [Transcription]; Region: COG2932
243265000065	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
243265000066	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
243265000067	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
243265000068	catalytic residues [active]
243265000069	catalytic nucleophile [active]
243265000070	Presynaptic Site I dimer interface [polypeptide binding]; other site
243265000071	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
243265000072	Synaptic Flat tetramer interface [polypeptide binding]; other site
243265000073	Synaptic Site I dimer interface [polypeptide binding]; other site
243265000074	DNA binding site [nucleotide binding]
243265000075	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
243265000076	DNA-binding interface [nucleotide binding]; DNA binding site
243265000077	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265000078	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265000079	Phage Tail Collar Domain; Region: Collar; pfam07484
243265000080	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
243265000081	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
243265000082	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
243265000083	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
243265000084	glutaminase active site [active]
243265000085	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
243265000086	dimer interface [polypeptide binding]; other site
243265000087	active site
243265000088	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
243265000089	dimer interface [polypeptide binding]; other site
243265000090	active site
243265000091	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
243265000092	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
243265000093	Substrate binding site; other site
243265000094	Mg++ binding site; other site
243265000095	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
243265000096	active site
243265000097	substrate binding site [chemical binding]; other site
243265000098	CoA binding site [chemical binding]; other site
243265000099	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
243265000100	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
243265000101	gamma subunit interface [polypeptide binding]; other site
243265000102	epsilon subunit interface [polypeptide binding]; other site
243265000103	LBP interface [polypeptide binding]; other site
243265000104	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
243265000105	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
243265000106	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
243265000107	alpha subunit interaction interface [polypeptide binding]; other site
243265000108	Walker A motif; other site
243265000109	ATP binding site [chemical binding]; other site
243265000110	Walker B motif; other site
243265000111	inhibitor binding site; inhibition site
243265000112	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
243265000113	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
243265000114	core domain interface [polypeptide binding]; other site
243265000115	delta subunit interface [polypeptide binding]; other site
243265000116	epsilon subunit interface [polypeptide binding]; other site
243265000117	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
243265000118	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
243265000119	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
243265000120	beta subunit interaction interface [polypeptide binding]; other site
243265000121	Walker A motif; other site
243265000122	ATP binding site [chemical binding]; other site
243265000123	Walker B motif; other site
243265000124	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
243265000125	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
243265000126	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
243265000127	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
243265000128	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
243265000129	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
243265000130	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
243265000131	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
243265000132	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
243265000133	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
243265000134	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265000135	S-adenosylmethionine binding site [chemical binding]; other site
243265000136	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
243265000137	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
243265000138	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
243265000139	FMN-binding protein MioC; Provisional; Region: PRK09004
243265000140	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
243265000141	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
243265000142	putative DNA binding site [nucleotide binding]; other site
243265000143	putative Zn2+ binding site [ion binding]; other site
243265000144	AsnC family; Region: AsnC_trans_reg; pfam01037
243265000145	asparagine synthetase AsnA; Provisional; Region: PRK05425
243265000146	motif 1; other site
243265000147	dimer interface [polypeptide binding]; other site
243265000148	active site
243265000149	motif 2; other site
243265000150	motif 3; other site
243265000151	hypothetical protein; Provisional; Region: yieM; PRK10997
243265000152	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
243265000153	metal ion-dependent adhesion site (MIDAS); other site
243265000154	regulatory ATPase RavA; Provisional; Region: PRK13531
243265000155	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265000156	Walker A motif; other site
243265000157	ATP binding site [chemical binding]; other site
243265000158	Walker B motif; other site
243265000159	arginine finger; other site
243265000160	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
243265000161	D-ribose pyranase; Provisional; Region: PRK11797
243265000162	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
243265000163	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
243265000164	Walker A/P-loop; other site
243265000165	ATP binding site [chemical binding]; other site
243265000166	Q-loop/lid; other site
243265000167	ABC transporter signature motif; other site
243265000168	Walker B; other site
243265000169	D-loop; other site
243265000170	H-loop/switch region; other site
243265000171	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
243265000172	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
243265000173	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
243265000174	TM-ABC transporter signature motif; other site
243265000175	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
243265000176	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
243265000177	ligand binding site [chemical binding]; other site
243265000178	dimerization interface [polypeptide binding]; other site
243265000179	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
243265000180	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
243265000181	substrate binding site [chemical binding]; other site
243265000182	dimer interface [polypeptide binding]; other site
243265000183	ATP binding site [chemical binding]; other site
243265000184	transcriptional repressor RbsR; Provisional; Region: PRK10423
243265000185	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
243265000186	DNA binding site [nucleotide binding]
243265000187	domain linker motif; other site
243265000188	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
243265000189	dimerization interface [polypeptide binding]; other site
243265000190	ligand binding site [chemical binding]; other site
243265000191	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265000192	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265000193	Truncated gene. Similar to C-terminal region of GntR-family transcriptional regulator
243265000194	Truncated gene. Similar to N-terminal region of GntR-family transcriptional regulator
243265000195	Transposase; Region: HTH_Tnp_1; cl17663
243265000196	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
243265000197	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265000198	Truncated gene. Similar to Unknown protein encoded by ISEc8 in one prophage
243265000199	Truncated gene. Similar to Unknown protein encoded by ISEc8 in one prophage
243265000200	Truncated gene. Similar to the C-terminal part of a transposase
243265000201	Truncated gene. Similar to the N-terminal region of transposase
243265000202	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
243265000203	Sulfatase; Region: Sulfatase; pfam00884
243265000204	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
243265000205	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
243265000206	Na binding site [ion binding]; other site
243265000207	Predicted membrane protein [Function unknown]; Region: COG3162
243265000208	acetyl-CoA synthetase; Provisional; Region: PRK00174
243265000209	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
243265000210	active site
243265000211	CoA binding site [chemical binding]; other site
243265000212	acyl-activating enzyme (AAE) consensus motif; other site
243265000213	AMP binding site [chemical binding]; other site
243265000214	acetate binding site [chemical binding]; other site
243265000215	superoxide dismutase; Provisional; Region: PRK10925
243265000216	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
243265000217	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
243265000218	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
243265000219	MOSC domain; Region: MOSC; pfam03473
243265000220	3-alpha domain; Region: 3-alpha; pfam03475
243265000221	RNA polymerase sigma factor; Provisional; Region: PRK12544
243265000222	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265000223	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265000224	DNA binding residues [nucleotide binding]
243265000225	Putative zinc-finger; Region: zf-HC2; pfam13490
243265000226	Predicted membrane protein [Function unknown]; Region: COG2259
243265000227	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; pfam09836
243265000228	hypothetical protein; Provisional; Region: PRK05409
243265000229	Predicted integral membrane protein (DUF2282); Region: DUF2282; pfam10048
243265000230	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
243265000231	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
243265000232	active site
243265000233	HIGH motif; other site
243265000234	dimer interface [polypeptide binding]; other site
243265000235	KMSKS motif; other site
243265000236	phosphoglycolate phosphatase; Provisional; Region: PRK13222
243265000237	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265000238	motif II; other site
243265000239	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
243265000240	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
243265000241	substrate binding site [chemical binding]; other site
243265000242	hexamer interface [polypeptide binding]; other site
243265000243	metal binding site [ion binding]; metal-binding site
243265000244	DNA adenine methylase; Provisional; Region: PRK10904
243265000245	hypothetical protein; Reviewed; Region: PRK11901
243265000246	cell division protein DamX; Validated; Region: PRK10905
243265000247	cell division protein DamX; Validated; Region: PRK10905
243265000248	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
243265000249	active site
243265000250	dimer interface [polypeptide binding]; other site
243265000251	metal binding site [ion binding]; metal-binding site
243265000252	shikimate kinase; Reviewed; Region: aroK; PRK00131
243265000253	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
243265000254	ADP binding site [chemical binding]; other site
243265000255	magnesium binding site [ion binding]; other site
243265000256	putative shikimate binding site; other site
243265000257	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
243265000258	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
243265000259	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
243265000260	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
243265000261	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
243265000262	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
243265000263	Transglycosylase; Region: Transgly; pfam00912
243265000264	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
243265000265	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
243265000266	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
243265000267	ADP-ribose binding site [chemical binding]; other site
243265000268	dimer interface [polypeptide binding]; other site
243265000269	active site
243265000270	nudix motif; other site
243265000271	metal binding site [ion binding]; metal-binding site
243265000272	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
243265000273	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
243265000274	RNA binding surface [nucleotide binding]; other site
243265000275	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
243265000276	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
243265000277	dimerization interface [polypeptide binding]; other site
243265000278	domain crossover interface; other site
243265000279	redox-dependent activation switch; other site
243265000280	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
243265000281	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
243265000282	active site
243265000283	substrate-binding site [chemical binding]; other site
243265000284	metal-binding site [ion binding]
243265000285	ATP binding site [chemical binding]; other site
243265000286	Pirin-related protein [General function prediction only]; Region: COG1741
243265000287	Pirin; Region: Pirin; pfam02678
243265000288	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265000289	dimer interface [polypeptide binding]; other site
243265000290	phosphorylation site [posttranslational modification]
243265000291	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265000292	ATP binding site [chemical binding]; other site
243265000293	Mg2+ binding site [ion binding]; other site
243265000294	G-X-G motif; other site
243265000295	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
243265000296	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265000297	active site
243265000298	phosphorylation site [posttranslational modification]
243265000299	intermolecular recognition site; other site
243265000300	dimerization interface [polypeptide binding]; other site
243265000301	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265000302	DNA binding residues [nucleotide binding]
243265000303	dimerization interface [polypeptide binding]; other site
243265000304	Domain of unknown function (DUF336); Region: DUF336; pfam03928
243265000305	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
243265000306	carbohydrate binding site [chemical binding]; other site
243265000307	alpha-1,6-glucosidases, pullulanase-type; Region: pullul_strch; TIGR02103
243265000308	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
243265000309	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
243265000310	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
243265000311	active site
243265000312	active site
243265000313	catalytic site [active]
243265000314	Domain of unknown function (DUF3372); Region: DUF3372; pfam11852
243265000315	Protein of unknown function (DUF3375); Region: DUF3375; pfam11855
243265000316	Domain of unknown function (DUF4194); Region: DUF4194; pfam13835
243265000317	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4913
243265000318	P-loop containing region of AAA domain; Region: AAA_29; pfam13555
243265000319	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
243265000320	Uncharacterized protein conserved in bacteria N-term (DUF3322); Region: DUF3322; pfam11795
243265000321	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4924
243265000322	Uncharacterized protein conserved in bacteria C-term(DUF2220); Region: DUF2220; pfam09983
243265000323	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
243265000324	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265000325	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
243265000326	dimerization interface [polypeptide binding]; other site
243265000327	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
243265000328	active site clefts [active]
243265000329	zinc binding site [ion binding]; other site
243265000330	dimer interface [polypeptide binding]; other site
243265000331	cyanate hydratase; Validated; Region: PRK02866
243265000332	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
243265000333	oligomer interface [polypeptide binding]; other site
243265000334	active site
243265000335	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
243265000336	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265000337	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265000338	Predicted flavoproteins [General function prediction only]; Region: COG2081
243265000339	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265000340	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
243265000341	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
243265000342	universal stress protein UspB; Provisional; Region: PRK04960
243265000343	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
243265000344	Ligand Binding Site [chemical binding]; other site
243265000345	glutamate dehydrogenase; Provisional; Region: PRK09414
243265000346	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
243265000347	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
243265000348	NAD(P) binding site [chemical binding]; other site
243265000349	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265000350	S-adenosylmethionine binding site [chemical binding]; other site
243265000351	oligopeptidase A; Provisional; Region: PRK10911
243265000352	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
243265000353	active site
243265000354	Zn binding site [ion binding]; other site
243265000355	integrase; Provisional; Region: PRK09692
243265000356	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
243265000357	active site
243265000358	Int/Topo IB signature motif; other site
243265000359	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
243265000360	Transposase [DNA replication, recombination, and repair]; Region: COG5421
243265000361	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
243265000362	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
243265000363	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
243265000364	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265000365	Transposase [DNA replication, recombination, and repair]; Region: COG5433
243265000366	Transposase [DNA replication, recombination, and repair]; Region: COG5433
243265000367	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
243265000368	MPN+ (JAMM) motif; other site
243265000369	Zinc-binding site [ion binding]; other site
243265000370	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
243265000371	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
243265000372	Methyltransferase domain; Region: Methyltransf_27; pfam13708
243265000373	Virulence protein [General function prediction only]; Region: COG3943
243265000374	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
243265000375	Truncated gene. Similar to the central region of Unknown protein
243265000376	beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431
243265000377	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
243265000378	Bacterial transcriptional regulator; Region: IclR; pfam01614
243265000379	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
243265000380	Pseudomonas fluorescens 4-hydroxymuconic semialdehyde dehydrogenase-like; Region: ALDH_HMSADH_HapE; cd07115
243265000381	NAD(P) binding site [chemical binding]; other site
243265000382	catalytic residues [active]
243265000383	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
243265000384	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit [Lipid metabolism]; Region: AtoA; COG2057
243265000385	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
243265000386	Maleylacetate reductase is involved in many aromatic compounds degradation pathways of aerobic microbes; Region: MAR; cd08177
243265000387	active site
243265000388	dimer interface [polypeptide binding]; other site
243265000389	metal binding site [ion binding]; metal-binding site
243265000390	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
243265000391	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
243265000392	dimer interface [polypeptide binding]; other site
243265000393	active site
243265000394	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
243265000395	iron-sulfur cluster [ion binding]; other site
243265000396	[2Fe-2S] cluster binding site [ion binding]; other site
243265000397	Truncated gene. Some high similarities with Unknown protein of Photorhabdus
243265000398	Truncated gene. Some high similarities with Unknown protein of Photorhabdus
243265000399	Truncated gene. Weakly similar to the C-terminal region of hemagglutinin/hemolysin-related protein
243265000400	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265000401	ATP binding site [chemical binding]; other site
243265000402	putative Mg++ binding site [ion binding]; other site
243265000403	nucleotide binding region [chemical binding]; other site
243265000404	helicase superfamily c-terminal domain; Region: HELICc; smart00490
243265000405	ATP-binding site [chemical binding]; other site
243265000406	AlkA N-terminal domain; Region: AlkA_N; cl05528
243265000407	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
243265000408	endonuclease III; Region: ENDO3c; smart00478
243265000409	minor groove reading motif; other site
243265000410	helix-hairpin-helix signature motif; other site
243265000411	substrate binding pocket [chemical binding]; other site
243265000412	active site
243265000413	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
243265000414	Amidinotransferase; Region: Amidinotransf; cl12043
243265000415	Fatty acid desaturase; Region: FA_desaturase; pfam00487
243265000416	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cd01060
243265000417	putative di-iron ligands [ion binding]; other site
243265000418	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
243265000419	EamA-like transporter family; Region: EamA; pfam00892
243265000420	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
243265000421	Beta-lactamase; Region: Beta-lactamase; pfam00144
243265000422	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
243265000423	Beta-lactamase; Region: Beta-lactamase; pfam00144
243265000424	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
243265000425	Beta-lactamase; Region: Beta-lactamase; pfam00144
243265000426	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
243265000427	Beta-lactamase; Region: Beta-lactamase; pfam00144
243265000428	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
243265000429	Beta-lactamase; Region: Beta-lactamase; pfam00144
243265000430	hypothetical protein; Provisional; Region: PRK01184
243265000431	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
243265000432	catalytic motif [active]
243265000433	Zn binding site [ion binding]; other site
243265000434	mannonate dehydratase; Provisional; Region: PRK03906
243265000435	mannonate dehydratase; Region: uxuA; TIGR00695
243265000436	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
243265000437	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
243265000438	DNA-binding site [nucleotide binding]; DNA binding site
243265000439	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
243265000440	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
243265000441	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265000442	membrane-bound complex binding site; other site
243265000443	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
243265000444	DctM-like transporters; Region: DctM; pfam06808
243265000445	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
243265000446	D-mannonate oxidoreductase; Provisional; Region: PRK15037
243265000447	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
243265000448	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
243265000449	Glucuronate isomerase; Region: UxaC; pfam02614
243265000450	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
243265000451	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
243265000452	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
243265000453	substrate binding site [chemical binding]; other site
243265000454	ATP binding site [chemical binding]; other site
243265000455	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
243265000456	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
243265000457	active site
243265000458	intersubunit interface [polypeptide binding]; other site
243265000459	catalytic residue [active]
243265000460	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
243265000461	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
243265000462	Glutamine amidotransferases class-II (GATase) asparagine synthase_betaLS-type.  Carbapenam synthetase (CarA) is an ATP/Mg2+-dependent enzyme that catalyzes the formation of the beta-lactam ring in (5R)-carbapenem-3-carboxylic acid biosynthesis.  CarA is...; Region: betaLS_CarA_N; cd01909
243265000463	putative active site [active]
243265000464	Domain of unknown function (DUF1933); Region: DUF1933; pfam09147
243265000465	betaLS subunit interaction site [polypeptide binding]; other site
243265000466	CarA subunit interaction site; other site
243265000467	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
243265000468	Ligand Binding Site [chemical binding]; other site
243265000469	Molecular Tunnel; other site
243265000470	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
243265000471	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
243265000472	substrate binding site [chemical binding]; other site
243265000473	oxyanion hole (OAH) forming residues; other site
243265000474	trimer interface [polypeptide binding]; other site
243265000475	Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668
243265000476	Proline dehydrogenase; Region: Pro_dh; cl03282
243265000477	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
243265000478	catalytic loop [active]
243265000479	iron binding site [ion binding]; other site
243265000480	Uncharacterized conserved protein [Function unknown]; Region: COG1262
243265000481	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
243265000482	Truncated gene. Similar to transposase, IS5 ssgr IS427 family (ISPlu7-p)
243265000483	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
243265000484	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
243265000485	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
243265000486	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
243265000487	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
243265000488	intramembrane serine protease GlpG; Provisional; Region: PRK10907
243265000489	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
243265000490	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
243265000491	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
243265000492	active site residue [active]
243265000493	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
243265000494	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
243265000495	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
243265000496	DNA utilization protein GntX; Provisional; Region: PRK11595
243265000497	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265000498	active site
243265000499	Truncated gene. Some similarities with biotin biosynthesis protein BioH of Escherichia coli
243265000500	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
243265000501	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
243265000502	active site
243265000503	HIGH motif; other site
243265000504	dimer interface [polypeptide binding]; other site
243265000505	KMSKS motif; other site
243265000506	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
243265000507	putative transporter; Provisional; Region: PRK10054
243265000508	carboxylesterase BioH; Provisional; Region: PRK10349
243265000509	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
243265000510	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265000511	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265000512	non-specific DNA binding site [nucleotide binding]; other site
243265000513	salt bridge; other site
243265000514	sequence-specific DNA binding site [nucleotide binding]; other site
243265000515	FeoC like transcriptional regulator; Region: FeoC; pfam09012
243265000516	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
243265000517	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
243265000518	G1 box; other site
243265000519	GTP/Mg2+ binding site [chemical binding]; other site
243265000520	Switch I region; other site
243265000521	G2 box; other site
243265000522	G3 box; other site
243265000523	Switch II region; other site
243265000524	G4 box; other site
243265000525	G5 box; other site
243265000526	Nucleoside recognition; Region: Gate; pfam07670
243265000527	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
243265000528	Nucleoside recognition; Region: Gate; pfam07670
243265000529	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
243265000530	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
243265000531	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
243265000532	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
243265000533	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
243265000534	RNA binding site [nucleotide binding]; other site
243265000535	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
243265000536	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
243265000537	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
243265000538	osmolarity response regulator; Provisional; Region: ompR; PRK09468
243265000539	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265000540	active site
243265000541	phosphorylation site [posttranslational modification]
243265000542	intermolecular recognition site; other site
243265000543	dimerization interface [polypeptide binding]; other site
243265000544	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
243265000545	DNA binding site [nucleotide binding]
243265000546	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
243265000547	HAMP domain; Region: HAMP; pfam00672
243265000548	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265000549	dimer interface [polypeptide binding]; other site
243265000550	phosphorylation site [posttranslational modification]
243265000551	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265000552	ATP binding site [chemical binding]; other site
243265000553	Mg2+ binding site [ion binding]; other site
243265000554	G-X-G motif; other site
243265000555	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265000556	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
243265000557	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265000558	dimer interface [polypeptide binding]; other site
243265000559	conserved gate region; other site
243265000560	putative PBP binding loops; other site
243265000561	ABC-ATPase subunit interface; other site
243265000562	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
243265000563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265000564	dimer interface [polypeptide binding]; other site
243265000565	conserved gate region; other site
243265000566	putative PBP binding loops; other site
243265000567	ABC-ATPase subunit interface; other site
243265000568	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
243265000569	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
243265000570	Walker A/P-loop; other site
243265000571	ATP binding site [chemical binding]; other site
243265000572	Q-loop/lid; other site
243265000573	ABC transporter signature motif; other site
243265000574	Walker B; other site
243265000575	D-loop; other site
243265000576	H-loop/switch region; other site
243265000577	transcriptional regulator PhoU; Provisional; Region: PRK11115
243265000578	PhoU domain; Region: PhoU; pfam01895
243265000579	PhoU domain; Region: PhoU; pfam01895
243265000580	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
243265000581	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265000582	substrate binding pocket [chemical binding]; other site
243265000583	membrane-bound complex binding site; other site
243265000584	hinge residues; other site
243265000585	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265000586	dimer interface [polypeptide binding]; other site
243265000587	conserved gate region; other site
243265000588	putative PBP binding loops; other site
243265000589	ABC-ATPase subunit interface; other site
243265000590	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
243265000591	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265000592	dimer interface [polypeptide binding]; other site
243265000593	conserved gate region; other site
243265000594	putative PBP binding loops; other site
243265000595	ABC-ATPase subunit interface; other site
243265000596	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265000597	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265000598	Possible hemagglutinin (DUF637); Region: DUF637; pfam04830
243265000599	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
243265000600	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
243265000601	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
243265000602	Truncated gene. Some similarities with binding protein component of ABC transporter
243265000603	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
243265000604	Der GTPase activator; Provisional; Region: PRK05244
243265000605	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
243265000606	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265000607	FeS/SAM binding site; other site
243265000608	HemN C-terminal domain; Region: HemN_C; pfam06969
243265000609	Methyltransferase domain; Region: Methyltransf_26; pfam13659
243265000610	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
243265000611	Transposase; Region: DDE_Tnp_ISL3; pfam01610
243265000612	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
243265000613	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265000614	active site
243265000615	phosphorylation site [posttranslational modification]
243265000616	intermolecular recognition site; other site
243265000617	dimerization interface [polypeptide binding]; other site
243265000618	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265000619	Walker A motif; other site
243265000620	ATP binding site [chemical binding]; other site
243265000621	Walker B motif; other site
243265000622	arginine finger; other site
243265000623	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
243265000624	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
243265000625	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
243265000626	putative active site [active]
243265000627	heme pocket [chemical binding]; other site
243265000628	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265000629	dimer interface [polypeptide binding]; other site
243265000630	phosphorylation site [posttranslational modification]
243265000631	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265000632	ATP binding site [chemical binding]; other site
243265000633	Mg2+ binding site [ion binding]; other site
243265000634	G-X-G motif; other site
243265000635	glutamine synthetase; Provisional; Region: glnA; PRK09469
243265000636	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
243265000637	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
243265000638	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
243265000639	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
243265000640	G1 box; other site
243265000641	putative GEF interaction site [polypeptide binding]; other site
243265000642	GTP/Mg2+ binding site [chemical binding]; other site
243265000643	Switch I region; other site
243265000644	G2 box; other site
243265000645	G3 box; other site
243265000646	Switch II region; other site
243265000647	G4 box; other site
243265000648	G5 box; other site
243265000649	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
243265000650	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
243265000651	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
243265000652	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
243265000653	Carbon starvation protein CstA; Region: CstA; pfam02554
243265000654	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
243265000655	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
243265000656	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265000657	motif II; other site
243265000658	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
243265000659	putative active site [active]
243265000660	dimerization interface [polypeptide binding]; other site
243265000661	putative tRNAtyr binding site [nucleotide binding]; other site
243265000662	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265000663	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
243265000664	Coenzyme A binding pocket [chemical binding]; other site
243265000665	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
243265000666	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
243265000667	nudix motif; other site
243265000668	AsmA family; Region: AsmA; pfam05170
243265000669	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
243265000670	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
243265000671	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
243265000672	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
243265000673	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
243265000674	Methyltransferase domain; Region: Methyltransf_31; pfam13847
243265000675	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265000676	S-adenosylmethionine binding site [chemical binding]; other site
243265000677	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
243265000678	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
243265000679	Fic family protein [Function unknown]; Region: COG3177
243265000680	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
243265000681	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
243265000682	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
243265000683	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
243265000684	generic binding surface II; other site
243265000685	ssDNA binding site; other site
243265000686	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265000687	ATP binding site [chemical binding]; other site
243265000688	putative Mg++ binding site [ion binding]; other site
243265000689	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265000690	nucleotide binding region [chemical binding]; other site
243265000691	ATP-binding site [chemical binding]; other site
243265000692	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
243265000693	active site
243265000694	DNA binding site [nucleotide binding]
243265000695	Int/Topo IB signature motif; other site
243265000696	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265000697	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265000698	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265000699	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265000700	putative fimbrial protein StaE; Provisional; Region: PRK15263
243265000701	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265000702	Fimbrial protein; Region: Fimbrial; pfam00419
243265000703	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265000704	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265000705	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265000706	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265000707	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265000708	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265000709	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
243265000710	PapC N-terminal domain; Region: PapC_N; pfam13954
243265000711	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
243265000712	PapC C-terminal domain; Region: PapC_C; pfam13953
243265000713	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
243265000714	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
243265000715	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
243265000716	Zn2+ binding site [ion binding]; other site
243265000717	Mg2+ binding site [ion binding]; other site
243265000718	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
243265000719	synthetase active site [active]
243265000720	NTP binding site [chemical binding]; other site
243265000721	metal binding site [ion binding]; metal-binding site
243265000722	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
243265000723	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
243265000724	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
243265000725	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
243265000726	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
243265000727	catalytic site [active]
243265000728	G-X2-G-X-G-K; other site
243265000729	Truncated gene. Some similarities with transposase, IS605 family
243265000730	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
243265000731	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
243265000732	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265000733	non-specific DNA binding site [nucleotide binding]; other site
243265000734	salt bridge; other site
243265000735	sequence-specific DNA binding site [nucleotide binding]; other site
243265000736	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
243265000737	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
243265000738	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
243265000739	nucleotide binding pocket [chemical binding]; other site
243265000740	K-X-D-G motif; other site
243265000741	catalytic site [active]
243265000742	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
243265000743	Predicted membrane protein [Function unknown]; Region: COG2860
243265000744	UPF0126 domain; Region: UPF0126; pfam03458
243265000745	UPF0126 domain; Region: UPF0126; pfam03458
243265000746	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
243265000747	hypothetical protein; Provisional; Region: PRK11616
243265000748	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
243265000749	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265000750	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265000751	homodimer interface [polypeptide binding]; other site
243265000752	catalytic residue [active]
243265000753	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
243265000754	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
243265000755	dimer interface [polypeptide binding]; other site
243265000756	motif 1; other site
243265000757	active site
243265000758	motif 2; other site
243265000759	motif 3; other site
243265000760	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
243265000761	DALR anticodon binding domain; Region: DALR_1; pfam05746
243265000762	Truncated gene. Some similarities with Unknown protein
243265000763	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
243265000764	Cytochrome P450; Region: p450; cl12078
243265000765	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
243265000766	catalytic residue [active]
243265000767	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
243265000768	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
243265000769	peptide binding site [polypeptide binding]; other site
243265000770	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
243265000771	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265000772	dimer interface [polypeptide binding]; other site
243265000773	conserved gate region; other site
243265000774	putative PBP binding loops; other site
243265000775	ABC-ATPase subunit interface; other site
243265000776	dipeptide transporter; Provisional; Region: PRK10913
243265000777	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265000778	putative PBP binding loops; other site
243265000779	dimer interface [polypeptide binding]; other site
243265000780	ABC-ATPase subunit interface; other site
243265000781	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
243265000782	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
243265000783	Walker A/P-loop; other site
243265000784	ATP binding site [chemical binding]; other site
243265000785	Q-loop/lid; other site
243265000786	ABC transporter signature motif; other site
243265000787	Walker B; other site
243265000788	D-loop; other site
243265000789	H-loop/switch region; other site
243265000790	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
243265000791	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
243265000792	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
243265000793	Walker A/P-loop; other site
243265000794	ATP binding site [chemical binding]; other site
243265000795	Q-loop/lid; other site
243265000796	ABC transporter signature motif; other site
243265000797	Walker B; other site
243265000798	D-loop; other site
243265000799	H-loop/switch region; other site
243265000800	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
243265000801	biofilm formation regulator HmsP; Provisional; Region: PRK11829
243265000802	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
243265000803	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
243265000804	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
243265000805	active site 1 [active]
243265000806	dimer interface [polypeptide binding]; other site
243265000807	hexamer interface [polypeptide binding]; other site
243265000808	active site 2 [active]
243265000809	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
243265000810	Homeodomain-like domain; Region: HTH_23; pfam13384
243265000811	Winged helix-turn helix; Region: HTH_29; pfam13551
243265000812	Winged helix-turn helix; Region: HTH_33; pfam13592
243265000813	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265000814	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265000815	Transposase IS200 like; Region: Y1_Tnp; pfam01797
243265000816	Truncated transposase, IS4 family
243265000817	Truncated transposase, IS4 family
243265000818	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265000819	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265000820	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265000821	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265000822	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265000823	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
243265000824	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
243265000825	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
243265000826	Inclusion body protein; Region: PixA; pfam12306
243265000827	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
243265000828	Transposase [DNA replication, recombination, and repair]; Region: COG5421
243265000829	Autoinducer binding domain; Region: Autoind_bind; pfam03472
243265000830	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265000831	DNA binding residues [nucleotide binding]
243265000832	dimerization interface [polypeptide binding]; other site
243265000833	Truncated gene. Some similarities with PTS system, maltose and glucose-specific II ABC
243265000834	Homeodomain-like domain; Region: HTH_23; pfam13384
243265000835	Winged helix-turn helix; Region: HTH_29; pfam13551
243265000836	Winged helix-turn helix; Region: HTH_33; pfam13592
243265000837	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265000838	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265000839	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265000840	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265000841	Some high similarities with Unknown protein of Photorhabdus.  truncated gene.
243265000842	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
243265000843	active site
243265000844	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265000845	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
243265000846	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
243265000847	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
243265000848	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
243265000849	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
243265000850	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
243265000851	DNA cytosine methylase; Provisional; Region: PRK10458
243265000852	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
243265000853	cofactor binding site; other site
243265000854	DNA binding site [nucleotide binding]
243265000855	substrate interaction site [chemical binding]; other site
243265000856	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
243265000857	additional DNA contacts [nucleotide binding]; other site
243265000858	mismatch recognition site; other site
243265000859	active site
243265000860	zinc binding site [ion binding]; other site
243265000861	DNA intercalation site [nucleotide binding]; other site
243265000862	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
243265000863	A nuclease of the HNH/ENDO VII superfamily with conserved LHH; Region: LHH; pfam14411
243265000864	Homeodomain-like domain; Region: HTH_23; pfam13384
243265000865	Winged helix-turn helix; Region: HTH_29; pfam13551
243265000866	Winged helix-turn helix; Region: HTH_33; pfam13592
243265000867	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265000868	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265000869	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
243265000870	Domain of unknown function (DUF4150); Region: DUF4150; pfam13665
243265000871	PAAR motif; Region: PAAR_motif; pfam05488
243265000872	RHS Repeat; Region: RHS_repeat; pfam05593
243265000873	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265000874	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
243265000875	RHS Repeat; Region: RHS_repeat; pfam05593
243265000876	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
243265000877	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265000878	Domain of unknown function (DUF1795); Region: DUF1795; pfam08786
243265000879	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
243265000880	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265000881	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265000883	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265000885	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
243265000886	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
243265000887	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
243265000888	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
243265000889	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
243265000890	Protein of unknown function (DUF3121); Region: DUF3121; pfam11319
243265000891	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
243265000892	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
243265000893	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265000894	Walker A motif; other site
243265000895	ATP binding site [chemical binding]; other site
243265000896	Walker B motif; other site
243265000897	arginine finger; other site
243265000898	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265000899	Walker A motif; other site
243265000900	ATP binding site [chemical binding]; other site
243265000901	Walker B motif; other site
243265000902	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
243265000903	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
243265000904	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
243265000905	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
243265000906	type VI secretion lipoprotein, VC_A0113 family; Region: VI_chp_3; TIGR03352
243265000907	type VI secretion system FHA domain protein; Region: VI_FHA; TIGR03354
243265000908	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
243265000909	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
243265000910	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
243265000911	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
243265000912	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
243265000913	Protein of unknown function (DUF877); Region: DUF877; pfam05943
243265000914	Protein of unknown function (DUF770); Region: DUF770; pfam05591
243265000915	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265000916	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
243265000917	glutathione reductase; Validated; Region: PRK06116
243265000918	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265000919	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
243265000920	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
243265000921	Domain of unknown function (DUF4297); Region: DUF4297; pfam14130
243265000922	AAA domain; Region: AAA_23; pfam13476
243265000923	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
243265000924	Walker A motif; other site
243265000925	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
243265000926	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
243265000927	GTP binding site; other site
243265000928	serine/threonine protein kinase; Provisional; Region: PRK11768
243265000929	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
243265000930	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
243265000931	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
243265000932	catalytic residues [active]
243265000933	hinge region; other site
243265000934	alpha helical domain; other site
243265000935	Divergent AAA domain; Region: AAA_4; pfam04326
243265000936	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
243265000937	PHP domain; Region: PHP; pfam02811
243265000938	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
243265000939	active site
243265000940	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265000941	AAA domain; Region: AAA_23; pfam13476
243265000942	Walker A/P-loop; other site
243265000943	ATP binding site [chemical binding]; other site
243265000944	Homeodomain-like domain; Region: HTH_23; pfam13384
243265000945	Winged helix-turn helix; Region: HTH_29; pfam13551
243265000946	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265000947	DNA polymerase I; Provisional; Region: PRK05755
243265000948	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
243265000949	active site
243265000950	metal binding site 1 [ion binding]; metal-binding site
243265000951	putative 5' ssDNA interaction site; other site
243265000952	metal binding site 3; metal-binding site
243265000953	metal binding site 2 [ion binding]; metal-binding site
243265000954	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
243265000955	putative DNA binding site [nucleotide binding]; other site
243265000956	putative metal binding site [ion binding]; other site
243265000957	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
243265000958	active site
243265000959	catalytic site [active]
243265000960	substrate binding site [chemical binding]; other site
243265000961	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
243265000962	active site
243265000963	DNA binding site [nucleotide binding]
243265000964	catalytic site [active]
243265000965	Truncated gene. Some similarities with Unknown protein
243265000966	Truncated gene. Some similarities with Unknown protein
243265000967	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
243265000968	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
243265000969	G1 box; other site
243265000970	GTP/Mg2+ binding site [chemical binding]; other site
243265000971	Switch I region; other site
243265000972	G2 box; other site
243265000973	G3 box; other site
243265000974	Switch II region; other site
243265000975	G4 box; other site
243265000976	G5 box; other site
243265000977	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
243265000978	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
243265000979	active site
243265000980	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
243265000981	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
243265000982	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
243265000983	glutamine binding [chemical binding]; other site
243265000984	catalytic triad [active]
243265000985	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
243265000986	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265000987	inhibitor-cofactor binding pocket; inhibition site
243265000988	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265000989	catalytic residue [active]
243265000990	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
243265000991	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
243265000992	ligand binding site [chemical binding]; other site
243265000993	flexible hinge region; other site
243265000994	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
243265000995	putative switch regulator; other site
243265000996	non-specific DNA interactions [nucleotide binding]; other site
243265000997	DNA binding site [nucleotide binding]
243265000998	sequence specific DNA binding site [nucleotide binding]; other site
243265000999	putative cAMP binding site [chemical binding]; other site
243265001000	hypothetical protein; Provisional; Region: PRK10738
243265001001	phosphoribulokinase; Provisional; Region: PRK15453
243265001002	hypothetical protein; Provisional; Region: PRK04966
243265001003	putative hydrolase; Provisional; Region: PRK10985
243265001004	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265001005	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265001006	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
243265001007	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
243265001008	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
243265001009	active site turn [active]
243265001010	phosphorylation site [posttranslational modification]
243265001011	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
243265001012	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
243265001013	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
243265001014	putative active site [active]
243265001015	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265001016	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
243265001017	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
243265001018	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
243265001019	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265001020	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265001021	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
243265001022	dimerization interface [polypeptide binding]; other site
243265001023	Protein of unknown function (DUF2968); Region: DUF2968; pfam11180
243265001024	Fimbrial protein; Region: Fimbrial; cl01416
243265001025	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
243265001026	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265001027	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265001028	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
243265001029	PapC N-terminal domain; Region: PapC_N; pfam13954
243265001030	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
243265001031	PapC C-terminal domain; Region: PapC_C; pfam13953
243265001032	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265001033	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265001034	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
243265001035	Int/Topo IB signature motif; other site
243265001036	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
243265001037	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265001038	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265001039	ABC transporter; Region: ABC_tran_2; pfam12848
243265001040	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265001041	Probable metal-binding protein (DUF2387); Region: DUF2387; pfam09526
243265001042	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
243265001043	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
243265001044	phi X174 lysis protein; Provisional; Region: PRK02793
243265001045	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
243265001046	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
243265001047	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
243265001048	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
243265001049	YheO-like PAS domain; Region: PAS_6; pfam08348
243265001050	HTH domain; Region: HTH_22; pfam13309
243265001051	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
243265001052	sulfur relay protein TusC; Validated; Region: PRK00211
243265001053	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
243265001054	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
243265001055	S17 interaction site [polypeptide binding]; other site
243265001056	S8 interaction site; other site
243265001057	16S rRNA interaction site [nucleotide binding]; other site
243265001058	streptomycin interaction site [chemical binding]; other site
243265001059	23S rRNA interaction site [nucleotide binding]; other site
243265001060	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
243265001061	30S ribosomal protein S7; Validated; Region: PRK05302
243265001062	elongation factor G; Reviewed; Region: PRK00007
243265001063	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
243265001064	G1 box; other site
243265001065	putative GEF interaction site [polypeptide binding]; other site
243265001066	GTP/Mg2+ binding site [chemical binding]; other site
243265001067	Switch I region; other site
243265001068	G2 box; other site
243265001069	G3 box; other site
243265001070	Switch II region; other site
243265001071	G4 box; other site
243265001072	G5 box; other site
243265001073	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
243265001074	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
243265001075	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
243265001076	elongation factor Tu; Reviewed; Region: PRK00049
243265001077	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
243265001078	G1 box; other site
243265001079	GEF interaction site [polypeptide binding]; other site
243265001080	GTP/Mg2+ binding site [chemical binding]; other site
243265001081	Switch I region; other site
243265001082	G2 box; other site
243265001083	G3 box; other site
243265001084	Switch II region; other site
243265001085	G4 box; other site
243265001086	G5 box; other site
243265001087	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
243265001088	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
243265001089	Antibiotic Binding Site [chemical binding]; other site
243265001090	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
243265001091	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
243265001092	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
243265001093	putative homodimer interface [polypeptide binding]; other site
243265001094	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
243265001095	heterodimer interface [polypeptide binding]; other site
243265001096	homodimer interface [polypeptide binding]; other site
243265001097	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
243265001098	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
243265001099	23S rRNA interface [nucleotide binding]; other site
243265001100	L7/L12 interface [polypeptide binding]; other site
243265001101	putative thiostrepton binding site; other site
243265001102	L25 interface [polypeptide binding]; other site
243265001103	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
243265001104	mRNA/rRNA interface [nucleotide binding]; other site
243265001105	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
243265001106	23S rRNA interface [nucleotide binding]; other site
243265001107	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
243265001108	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
243265001109	core dimer interface [polypeptide binding]; other site
243265001110	peripheral dimer interface [polypeptide binding]; other site
243265001111	L10 interface [polypeptide binding]; other site
243265001112	L11 interface [polypeptide binding]; other site
243265001113	putative EF-Tu interaction site [polypeptide binding]; other site
243265001114	putative EF-G interaction site [polypeptide binding]; other site
243265001115	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
243265001116	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
243265001117	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
243265001118	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
243265001119	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
243265001120	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
243265001121	RPB3 interaction site [polypeptide binding]; other site
243265001122	RPB1 interaction site [polypeptide binding]; other site
243265001123	RPB11 interaction site [polypeptide binding]; other site
243265001124	RPB10 interaction site [polypeptide binding]; other site
243265001125	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
243265001126	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
243265001127	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
243265001128	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
243265001129	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
243265001130	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
243265001131	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
243265001132	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
243265001133	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
243265001134	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
243265001135	DNA binding site [nucleotide binding]
243265001136	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
243265001137	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
243265001138	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
243265001139	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265001140	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265001141	non-specific DNA binding site [nucleotide binding]; other site
243265001142	salt bridge; other site
243265001143	sequence-specific DNA binding site [nucleotide binding]; other site
243265001144	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
243265001145	Protein similar to CwfJ C-terminus 2; Region: CwfJ_C_2; pfam04676
243265001146	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
243265001147	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
243265001148	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265001149	catalytic residue [active]
243265001150	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
243265001151	active site
243265001152	nucleotide binding site [chemical binding]; other site
243265001153	HIGH motif; other site
243265001154	KMSKS motif; other site
243265001155	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
243265001156	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
243265001157	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
243265001158	putative ADP-binding pocket [chemical binding]; other site
243265001159	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
243265001160	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
243265001161	maltose regulon periplasmic protein; Provisional; Region: PRK10564
243265001162	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
243265001163	trimer interface; other site
243265001164	sugar binding site [chemical binding]; other site
243265001165	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
243265001166	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
243265001167	Walker A/P-loop; other site
243265001168	ATP binding site [chemical binding]; other site
243265001169	Q-loop/lid; other site
243265001170	ABC transporter signature motif; other site
243265001171	Walker B; other site
243265001172	D-loop; other site
243265001173	H-loop/switch region; other site
243265001174	TOBE domain; Region: TOBE_2; pfam08402
243265001175	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
243265001176	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
243265001177	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265001178	dimer interface [polypeptide binding]; other site
243265001179	conserved gate region; other site
243265001180	putative PBP binding loops; other site
243265001181	ABC-ATPase subunit interface; other site
243265001182	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
243265001183	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265001184	dimer interface [polypeptide binding]; other site
243265001185	conserved gate region; other site
243265001186	putative PBP binding loops; other site
243265001187	ABC-ATPase subunit interface; other site
243265001188	Sulfatase; Region: Sulfatase; cl17466
243265001189	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
243265001190	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265001191	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265001192	This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990
243265001193	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
243265001194	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
243265001195	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
243265001196	PAAR motif; Region: PAAR_motif; pfam05488
243265001197	Homeodomain-like domain; Region: HTH_23; pfam13384
243265001198	Winged helix-turn helix; Region: HTH_29; pfam13551
243265001199	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265001200	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265001201	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
243265001202	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
243265001203	maltodextrin phosphorylase; Provisional; Region: PRK14985
243265001204	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
243265001205	active site pocket [active]
243265001206	transcriptional regulator MalT; Provisional; Region: PRK04841
243265001207	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
243265001208	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265001209	DNA binding residues [nucleotide binding]
243265001210	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265001211	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
243265001212	putative substrate translocation pore; other site
243265001213	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
243265001214	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265001215	inhibitor-cofactor binding pocket; inhibition site
243265001216	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265001217	catalytic residue [active]
243265001218	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
243265001219	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
243265001220	NAD(P) binding site [chemical binding]; other site
243265001221	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
243265001222	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265001223	active site
243265001224	motif I; other site
243265001225	motif II; other site
243265001226	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265001227	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265001228	putative substrate translocation pore; other site
243265001229	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
243265001230	Homeodomain-like domain; Region: HTH_23; pfam13384
243265001231	Winged helix-turn helix; Region: HTH_29; pfam13551
243265001232	Winged helix-turn helix; Region: HTH_33; pfam13592
243265001233	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265001234	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265001235	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
243265001236	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
243265001237	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265001238	FeS/SAM binding site; other site
243265001239	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
243265001240	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
243265001241	ThiS interaction site; other site
243265001242	putative active site [active]
243265001243	tetramer interface [polypeptide binding]; other site
243265001244	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
243265001245	thiS-thiF/thiG interaction site; other site
243265001246	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
243265001247	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
243265001248	ATP binding site [chemical binding]; other site
243265001249	substrate interface [chemical binding]; other site
243265001250	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
243265001251	thiamine phosphate binding site [chemical binding]; other site
243265001252	active site
243265001253	pyrophosphate binding site [ion binding]; other site
243265001254	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
243265001255	ThiC-associated domain; Region: ThiC-associated; pfam13667
243265001256	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
243265001257	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
243265001258	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
243265001259	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
243265001260	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
243265001261	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
243265001262	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
243265001263	putative NADH binding site [chemical binding]; other site
243265001264	putative active site [active]
243265001265	nudix motif; other site
243265001266	putative metal binding site [ion binding]; other site
243265001267	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
243265001268	substrate binding site [chemical binding]; other site
243265001269	active site
243265001270	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
243265001271	Active_site [active]
243265001272	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
243265001273	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
243265001274	IHF dimer interface [polypeptide binding]; other site
243265001275	IHF - DNA interface [nucleotide binding]; other site
243265001276	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
243265001277	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
243265001278	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
243265001279	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
243265001280	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
243265001281	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
243265001282	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
243265001283	purine monophosphate binding site [chemical binding]; other site
243265001284	dimer interface [polypeptide binding]; other site
243265001285	putative catalytic residues [active]
243265001286	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
243265001287	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
243265001288	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
243265001289	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
243265001290	DNA binding site [nucleotide binding]
243265001291	domain linker motif; other site
243265001292	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
243265001293	putative ligand binding site [chemical binding]; other site
243265001294	putative dimerization interface [polypeptide binding]; other site
243265001295	Shikimate kinase; Region: SKI; pfam01202
243265001296	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
243265001297	low affinity gluconate transporter; Provisional; Region: PRK10472
243265001298	gluconate transporter; Region: gntP; TIGR00791
243265001299	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
243265001300	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
243265001301	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
243265001302	oxyanion hole [active]
243265001303	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
243265001304	active site
243265001305	oxyanion hole [active]
243265001306	catalytic triad [active]
243265001307	SGNH_peri2; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri2; cd01829
243265001308	active site
243265001309	catalytic triad [active]
243265001310	oxyanion hole [active]
243265001311	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
243265001312	hypothetical protein; Provisional; Region: PRK10356
243265001313	Fimbrial protein; Region: Fimbrial; pfam00419
243265001314	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
243265001315	PapC N-terminal domain; Region: PapC_N; pfam13954
243265001316	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
243265001317	PapC C-terminal domain; Region: PapC_C; pfam13953
243265001318	fimbrial chaperone protein PefD; Provisional; Region: PRK15211
243265001319	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265001320	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265001321	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265001322	Protein of unknown function (DUF4056); Region: DUF4056; pfam13265
243265001323	Surface antigen; Region: Bac_surface_Ag; pfam01103
243265001324	benzoate transporter; Region: benE; TIGR00843
243265001325	Benzoate membrane transport protein; Region: BenE; pfam03594
243265001326	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
243265001327	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
243265001328	Family description; Region: VCBS; pfam13517
243265001329	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
243265001330	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
243265001331	Truncated gene. Highly similar to the C-terminal region of insecticidal toxin complex protein TcaA and TcaB
243265001332	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
243265001333	active site
243265001334	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
243265001335	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
243265001336	Zn2+ binding site [ion binding]; other site
243265001337	Mg2+ binding site [ion binding]; other site
243265001338	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
243265001339	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
243265001340	Nucleoside recognition; Region: Gate; pfam07670
243265001341	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
243265001342	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
243265001343	intersubunit interface [polypeptide binding]; other site
243265001344	active site
243265001345	catalytic residue [active]
243265001346	phosphopentomutase; Provisional; Region: PRK05362
243265001347	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
243265001348	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
243265001349	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
243265001350	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
243265001351	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
243265001352	homodimer interface [polypeptide binding]; other site
243265001353	substrate-cofactor binding pocket; other site
243265001354	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265001355	catalytic residue [active]
243265001356	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
243265001357	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
243265001358	dimer interface [polypeptide binding]; other site
243265001359	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265001360	catalytic residue [active]
243265001361	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
243265001362	FOG: CBS domain [General function prediction only]; Region: COG0517
243265001363	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
243265001364	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265001365	Coenzyme A binding pocket [chemical binding]; other site
243265001366	Protein of unknown function (DUF692); Region: DUF692; cl01263
243265001367	Protein of unknown function (DUF692); Region: DUF692; cl01263
243265001368	Truncated transposase, IS5 family (ISPlu14-p)
243265001369	Truncated gene. Similar to C-terminal region of transposase
243265001370	Probable transposase; Region: OrfB_IS605; pfam01385
243265001371	Uncharacterized protein conserved in bacteria (DUF2247); Region: DUF2247; cl01763
243265001372	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265001373	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
243265001374	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
243265001375	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
243265001376	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265001377	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265001378	active site
243265001379	Int/Topo IB signature motif; other site
243265001380	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265001381	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265001382	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265001383	interdomain interaction site; other site
243265001384	active site
243265001385	metal binding site [ion binding]; metal-binding site
243265001386	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265001387	non-specific DNA binding site [nucleotide binding]; other site
243265001388	salt bridge; other site
243265001389	sequence-specific DNA binding site [nucleotide binding]; other site
243265001390	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265001391	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
243265001392	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265001393	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
243265001394	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265001395	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265001396	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
243265001397	A nuclease of the HNH/ENDO VII superfamily with conserved LHH; Region: LHH; pfam14411
243265001398	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
243265001399	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
243265001400	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
243265001401	hypothetical protein; Provisional; Region: PRK11246
243265001402	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
243265001403	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
243265001404	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265001405	motif II; other site
243265001406	DNA repair protein RadA; Region: sms; TIGR00416
243265001407	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
243265001408	Walker A motif/ATP binding site; other site
243265001409	ATP binding site [chemical binding]; other site
243265001410	Walker B motif; other site
243265001411	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
243265001412	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265001413	non-specific DNA binding site [nucleotide binding]; other site
243265001414	salt bridge; other site
243265001415	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
243265001416	sequence-specific DNA binding site [nucleotide binding]; other site
243265001417	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
243265001418	active site
243265001419	nucleotide binding site [chemical binding]; other site
243265001420	HIGH motif; other site
243265001421	KMSKS motif; other site
243265001422	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
243265001423	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265001424	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
243265001425	Walker A/P-loop; other site
243265001426	ATP binding site [chemical binding]; other site
243265001427	Q-loop/lid; other site
243265001428	ABC transporter signature motif; other site
243265001429	Walker B; other site
243265001430	D-loop; other site
243265001431	H-loop/switch region; other site
243265001432	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
243265001433	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265001434	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265001435	ABC transporter; Region: ABC_tran_2; pfam12848
243265001436	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265001437	lytic murein transglycosylase; Provisional; Region: PRK11619
243265001438	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
243265001439	N-acetyl-D-glucosamine binding site [chemical binding]; other site
243265001440	catalytic residue [active]
243265001441	Trp operon repressor; Provisional; Region: PRK01381
243265001442	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
243265001443	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
243265001444	catalytic core [active]
243265001445	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
243265001446	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265001447	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
243265001448	hypothetical protein; Provisional; Region: PRK10756
243265001449	CreA protein; Region: CreA; pfam05981
243265001450	two-component response regulator; Provisional; Region: PRK11173
243265001451	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265001452	active site
243265001453	phosphorylation site [posttranslational modification]
243265001454	intermolecular recognition site; other site
243265001455	dimerization interface [polypeptide binding]; other site
243265001456	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
243265001457	DNA binding site [nucleotide binding]
243265001458	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
243265001459	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
243265001460	putative catalytic residues [active]
243265001461	putative nucleotide binding site [chemical binding]; other site
243265001462	putative aspartate binding site [chemical binding]; other site
243265001463	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
243265001464	dimer interface [polypeptide binding]; other site
243265001465	putative threonine allosteric regulatory site; other site
243265001466	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
243265001467	putative threonine allosteric regulatory site; other site
243265001468	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
243265001469	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
243265001470	homoserine kinase; Provisional; Region: PRK01212
243265001471	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
243265001472	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
243265001473	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
243265001474	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
243265001475	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265001476	catalytic residue [active]
243265001477	hypothetical protein; Validated; Region: PRK02101
243265001478	H+ Antiporter protein; Region: 2A0121; TIGR00900
243265001479	transaldolase-like protein; Provisional; Region: PTZ00411
243265001480	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
243265001481	active site
243265001482	dimer interface [polypeptide binding]; other site
243265001483	catalytic residue [active]
243265001484	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
243265001485	MPT binding site; other site
243265001486	trimer interface [polypeptide binding]; other site
243265001487	chorismate mutase; Provisional; Region: PRK08055
243265001488	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
243265001489	ATPase family associated with various cellular activities (AAA); Region: AAA; pfam00004
243265001490	Walker B motif; other site
243265001491	arginine finger; other site
243265001492	Truncated gene. Similar to the N-terminal region of Unknown protein
243265001493	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265001494	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265001495	Truncated gene. Similar to the C-terminal region of Unknown protein
243265001496	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
243265001497	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
243265001498	dimer interface [polypeptide binding]; other site
243265001499	active site
243265001500	galactokinase; Provisional; Region: PRK05101
243265001501	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
243265001502	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
243265001503	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
243265001504	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
243265001505	active site
243265001506	catalytic residues [active]
243265001507	hypothetical protein; Provisional; Region: PRK10659
243265001508	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
243265001509	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
243265001510	nucleotide binding site [chemical binding]; other site
243265001511	chaperone protein DnaJ; Provisional; Region: PRK10767
243265001512	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
243265001513	HSP70 interaction site [polypeptide binding]; other site
243265001514	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
243265001515	substrate binding site [polypeptide binding]; other site
243265001516	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
243265001517	Zn binding sites [ion binding]; other site
243265001518	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
243265001519	dimer interface [polypeptide binding]; other site
243265001520	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
243265001521	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
243265001522	beta-galactosidase; Region: BGL; TIGR03356
243265001523	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
243265001524	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
243265001525	active site turn [active]
243265001526	phosphorylation site [posttranslational modification]
243265001527	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
243265001528	transcriptional antiterminator BglG; Provisional; Region: PRK09772
243265001529	CAT RNA binding domain; Region: CAT_RBD; smart01061
243265001530	PRD domain; Region: PRD; pfam00874
243265001531	PRD domain; Region: PRD; pfam00874
243265001532	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
243265001533	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
243265001534	active site turn [active]
243265001535	phosphorylation site [posttranslational modification]
243265001536	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
243265001537	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
243265001538	HPr interaction site; other site
243265001539	glycerol kinase (GK) interaction site [polypeptide binding]; other site
243265001540	active site
243265001541	phosphorylation site [posttranslational modification]
243265001542	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
243265001543	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
243265001544	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265001545	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
243265001546	putative dimerization interface [polypeptide binding]; other site
243265001547	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
243265001548	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
243265001549	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
243265001550	active site
243265001551	Riboflavin kinase; Region: Flavokinase; smart00904
243265001552	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
243265001553	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
243265001554	active site
243265001555	HIGH motif; other site
243265001556	nucleotide binding site [chemical binding]; other site
243265001557	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
243265001558	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
243265001559	active site
243265001560	KMSKS motif; other site
243265001561	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
243265001562	tRNA binding surface [nucleotide binding]; other site
243265001563	anticodon binding site; other site
243265001564	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
243265001565	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
243265001566	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
243265001567	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
243265001568	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
243265001569	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
243265001570	Truncated gene. Similar to transposase, IS982 family
243265001571	Truncated gene. Weakly similar to prophage cp4-57 regulatory protein AlpA
243265001572	Viral (Superfamily 1) RNA helicase; Region: Viral_helicase1; pfam01443
243265001573	AAA ATPase domain; Region: AAA_15; pfam13175
243265001574	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265001575	Walker A/P-loop; other site
243265001576	ATP binding site [chemical binding]; other site
243265001577	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
243265001578	putative active site [active]
243265001579	putative metal-binding site [ion binding]; other site
243265001580	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
243265001581	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
243265001582	cofactor binding site; other site
243265001583	DNA binding site [nucleotide binding]
243265001584	substrate interaction site [chemical binding]; other site
243265001585	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
243265001586	dihydrodipicolinate reductase; Provisional; Region: PRK00048
243265001587	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
243265001588	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
243265001589	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
243265001590	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
243265001591	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
243265001592	catalytic site [active]
243265001593	subunit interface [polypeptide binding]; other site
243265001594	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
243265001595	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
243265001596	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
243265001597	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
243265001598	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
243265001599	ATP-grasp domain; Region: ATP-grasp_4; cl17255
243265001600	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
243265001601	IMP binding site; other site
243265001602	dimer interface [polypeptide binding]; other site
243265001603	interdomain contacts; other site
243265001604	partial ornithine binding site; other site
243265001605	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
243265001606	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
243265001607	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
243265001608	folate binding site [chemical binding]; other site
243265001609	NADP+ binding site [chemical binding]; other site
243265001610	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
243265001611	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
243265001612	active site
243265001613	metal binding site [ion binding]; metal-binding site
243265001614	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
243265001615	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
243265001616	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265001617	S-adenosylmethionine binding site [chemical binding]; other site
243265001618	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
243265001619	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
243265001620	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
243265001621	SurA N-terminal domain; Region: SurA_N; pfam09312
243265001622	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
243265001623	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
243265001624	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
243265001625	OstA-like protein; Region: OstA; pfam03968
243265001626	Organic solvent tolerance protein; Region: OstA_C; pfam04453
243265001627	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
243265001628	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
243265001629	putative metal binding site [ion binding]; other site
243265001630	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
243265001631	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
243265001632	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
243265001633	active site
243265001634	ATP-dependent helicase HepA; Validated; Region: PRK04914
243265001635	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265001636	ATP binding site [chemical binding]; other site
243265001637	putative Mg++ binding site [ion binding]; other site
243265001638	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265001639	nucleotide binding region [chemical binding]; other site
243265001640	ATP-binding site [chemical binding]; other site
243265001641	Some similarities with DNA polymerase II
243265001642	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
243265001643	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265001644	Walker A/P-loop; other site
243265001645	ATP binding site [chemical binding]; other site
243265001646	Q-loop/lid; other site
243265001647	ABC transporter signature motif; other site
243265001648	Walker B; other site
243265001649	D-loop; other site
243265001650	H-loop/switch region; other site
243265001651	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
243265001652	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265001653	dimer interface [polypeptide binding]; other site
243265001654	conserved gate region; other site
243265001655	putative PBP binding loops; other site
243265001656	ABC-ATPase subunit interface; other site
243265001657	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265001658	dimer interface [polypeptide binding]; other site
243265001659	conserved gate region; other site
243265001660	putative PBP binding loops; other site
243265001661	ABC-ATPase subunit interface; other site
243265001662	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
243265001663	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
243265001664	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
243265001665	putative active site [active]
243265001666	Ap4A binding site [chemical binding]; other site
243265001667	nudix motif; other site
243265001668	putative metal binding site [ion binding]; other site
243265001669	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
243265001670	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
243265001671	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
243265001672	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
243265001673	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
243265001674	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
243265001675	thymidylate synthase; Reviewed; Region: thyA; PRK01827
243265001676	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
243265001677	dimerization interface [polypeptide binding]; other site
243265001678	active site
243265001679	hypothetical protein; Provisional; Region: PRK10506
243265001680	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
243265001681	hypothetical protein; Provisional; Region: PRK10557
243265001682	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
243265001683	Protein of unknown function (DUF2509); Region: DUF2509; pfam10713
243265001684	hypothetical protein; Provisional; Region: PRK10332
243265001685	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
243265001686	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
243265001687	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
243265001688	protease3; Provisional; Region: PRK15101
243265001689	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
243265001690	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
243265001691	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
243265001692	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
243265001693	Family description; Region: UvrD_C_2; pfam13538
243265001694	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
243265001695	AAA domain; Region: AAA_30; pfam13604
243265001696	Family description; Region: UvrD_C_2; pfam13538
243265001697	A sub-family of peptidase C39 which contains Cyclolysin and Hemolysin processing peptidases.  Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine...; Region: Peptidase_C39_likeA; cd02417
243265001698	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
243265001699	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265001700	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265001701	Walker A/P-loop; other site
243265001702	ATP binding site [chemical binding]; other site
243265001703	Q-loop/lid; other site
243265001704	ABC transporter signature motif; other site
243265001705	Walker B; other site
243265001706	D-loop; other site
243265001707	H-loop/switch region; other site
243265001708	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
243265001709	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265001710	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265001711	Peptidase S8 family domain in Protein convertases; Region: Peptidases_S8_Protein_convertases_Kexins_Furin-lik; cd04059
243265001712	calcium binding site 1 [ion binding]; other site
243265001713	active site
243265001714	catalytic triad [active]
243265001715	calcium binding site 2 [ion binding]; other site
243265001716	calcium binding site 3 [ion binding]; other site
243265001717	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
243265001718	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
243265001719	N-acetylglutamate synthase; Validated; Region: PRK05279
243265001720	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
243265001721	putative feedback inhibition sensing region; other site
243265001722	putative nucleotide binding site [chemical binding]; other site
243265001723	putative substrate binding site [chemical binding]; other site
243265001724	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265001725	Coenzyme A binding pocket [chemical binding]; other site
243265001726	AMIN domain; Region: AMIN; pfam11741
243265001727	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
243265001728	active site
243265001729	metal binding site [ion binding]; metal-binding site
243265001730	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
243265001731	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
243265001732	murein transglycosylase A; Provisional; Region: mltA; PRK11162
243265001733	MltA specific insert domain; Region: MltA; pfam03562
243265001734	3D domain; Region: 3D; pfam06725
243265001735	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
243265001736	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
243265001737	putative ATP binding site [chemical binding]; other site
243265001738	putative substrate interface [chemical binding]; other site
243265001739	cysteine desulfurase, sulfur acceptor subunit CsdE; Region: FeS_syn_CsdE; TIGR03391
243265001740	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
243265001741	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
243265001742	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265001743	catalytic residue [active]
243265001744	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
243265001745	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265001746	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
243265001747	dimerization interface [polypeptide binding]; other site
243265001748	substrate binding pocket [chemical binding]; other site
243265001749	hypothetical protein; Provisional; Region: PRK10873
243265001750	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
243265001751	FtsJ-like methyltransferase; Region: FtsJ; cl17430
243265001752	Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria. They may be secreted into the medium via a mechanism found in gram-negative bacteria, that does not...; Region: ZnMc_serralysin_like; cd04277
243265001753	active site
243265001754	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
243265001755	Protease inhibitor Inh; Region: Inh; pfam02974
243265001756	ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only]; Region: ArpD; COG4618
243265001757	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
243265001758	Walker A/P-loop; other site
243265001759	ATP binding site [chemical binding]; other site
243265001760	Q-loop/lid; other site
243265001761	ABC transporter signature motif; other site
243265001762	Walker B; other site
243265001763	D-loop; other site
243265001764	H-loop/switch region; other site
243265001765	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
243265001766	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265001767	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265001768	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
243265001769	flap endonuclease-like protein; Provisional; Region: PRK09482
243265001770	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
243265001771	active site
243265001772	metal binding site 1 [ion binding]; metal-binding site
243265001773	putative 5' ssDNA interaction site; other site
243265001774	metal binding site 3; metal-binding site
243265001775	metal binding site 2 [ion binding]; metal-binding site
243265001776	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
243265001777	putative DNA binding site [nucleotide binding]; other site
243265001778	putative metal binding site [ion binding]; other site
243265001779	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
243265001780	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
243265001781	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
243265001782	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
243265001783	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
243265001784	SecY interacting protein Syd; Provisional; Region: PRK04968
243265001785	tRNA pseudouridine synthase C; Region: DUF446; pfam04287
243265001786	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
243265001787	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
243265001788	probable active site [active]
243265001789	flavodoxin; Provisional; Region: PRK08105
243265001790	hypothetical protein; Provisional; Region: PRK13677
243265001791	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
243265001792	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
243265001793	trimer interface [polypeptide binding]; other site
243265001794	active site
243265001795	substrate binding site [chemical binding]; other site
243265001796	CoA binding site [chemical binding]; other site
243265001797	PII uridylyl-transferase; Provisional; Region: PRK05007
243265001798	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
243265001799	metal binding triad; other site
243265001800	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
243265001801	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
243265001802	Zn2+ binding site [ion binding]; other site
243265001803	Mg2+ binding site [ion binding]; other site
243265001804	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
243265001805	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
243265001806	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
243265001807	active site
243265001808	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
243265001809	rRNA interaction site [nucleotide binding]; other site
243265001810	S8 interaction site; other site
243265001811	putative laminin-1 binding site; other site
243265001812	elongation factor Ts; Provisional; Region: tsf; PRK09377
243265001813	UBA/TS-N domain; Region: UBA; pfam00627
243265001814	Elongation factor TS; Region: EF_TS; pfam00889
243265001815	Elongation factor TS; Region: EF_TS; pfam00889
243265001816	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
243265001817	putative nucleotide binding site [chemical binding]; other site
243265001818	uridine monophosphate binding site [chemical binding]; other site
243265001819	homohexameric interface [polypeptide binding]; other site
243265001820	ribosome recycling factor; Reviewed; Region: frr; PRK00083
243265001821	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
243265001822	hinge region; other site
243265001823	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
243265001824	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
243265001825	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
243265001826	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
243265001827	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
243265001828	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
243265001829	catalytic residue [active]
243265001830	putative FPP diphosphate  binding site; other site
243265001831	putative FPP binding hydrophobic cleft; other site
243265001832	dimer interface [polypeptide binding]; other site
243265001833	putative IPP diphosphate binding site; other site
243265001834	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
243265001835	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
243265001836	zinc metallopeptidase RseP; Provisional; Region: PRK10779
243265001837	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
243265001838	active site
243265001839	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
243265001840	protein binding site [polypeptide binding]; other site
243265001841	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
243265001842	protein binding site [polypeptide binding]; other site
243265001843	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
243265001844	putative substrate binding region [chemical binding]; other site
243265001845	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
243265001846	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
243265001847	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
243265001848	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
243265001849	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
243265001850	Surface antigen; Region: Bac_surface_Ag; pfam01103
243265001851	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
243265001852	periplasmic chaperone; Provisional; Region: PRK10780
243265001853	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
243265001854	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
243265001855	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
243265001856	trimer interface [polypeptide binding]; other site
243265001857	active site
243265001858	UDP-GlcNAc binding site [chemical binding]; other site
243265001859	lipid binding site [chemical binding]; lipid-binding site
243265001860	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
243265001861	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
243265001862	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
243265001863	active site
243265001864	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
243265001865	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
243265001866	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
243265001867	RNA/DNA hybrid binding site [nucleotide binding]; other site
243265001868	active site
243265001869	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
243265001870	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
243265001871	putative active site [active]
243265001872	putative PHP Thumb interface [polypeptide binding]; other site
243265001873	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
243265001874	generic binding surface II; other site
243265001875	generic binding surface I; other site
243265001876	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
243265001877	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
243265001878	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
243265001879	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
243265001880	Ligand Binding Site [chemical binding]; other site
243265001881	TilS substrate binding domain; Region: TilS; pfam09179
243265001882	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
243265001883	Rho-binding antiterminator; Provisional; Region: PRK11625
243265001884	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
243265001885	NlpE N-terminal domain; Region: NlpE; pfam04170
243265001886	prolyl-tRNA synthetase; Provisional; Region: PRK09194
243265001887	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
243265001888	dimer interface [polypeptide binding]; other site
243265001889	motif 1; other site
243265001890	active site
243265001891	motif 2; other site
243265001892	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
243265001893	putative deacylase active site [active]
243265001894	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
243265001895	active site
243265001896	motif 3; other site
243265001897	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
243265001898	anticodon binding site; other site
243265001899	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
243265001900	homodimer interaction site [polypeptide binding]; other site
243265001901	cofactor binding site; other site
243265001902	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
243265001903	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
243265001904	lipoprotein, YaeC family; Region: TIGR00363
243265001905	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265001906	dimer interface [polypeptide binding]; other site
243265001907	conserved gate region; other site
243265001908	ABC-ATPase subunit interface; other site
243265001909	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
243265001910	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
243265001911	Walker A/P-loop; other site
243265001912	ATP binding site [chemical binding]; other site
243265001913	Q-loop/lid; other site
243265001914	ABC transporter signature motif; other site
243265001915	Walker B; other site
243265001916	D-loop; other site
243265001917	H-loop/switch region; other site
243265001918	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
243265001919	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
243265001920	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265001921	active site
243265001922	motif I; other site
243265001923	motif II; other site
243265001924	hypothetical protein; Provisional; Region: PRK05421
243265001925	putative catalytic site [active]
243265001926	putative metal binding site [ion binding]; other site
243265001927	putative phosphate binding site [ion binding]; other site
243265001928	putative catalytic site [active]
243265001929	putative phosphate binding site [ion binding]; other site
243265001930	putative metal binding site [ion binding]; other site
243265001931	putative proline-specific permease; Provisional; Region: proY; PRK10580
243265001932	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
243265001933	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
243265001934	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
243265001935	active site
243265001936	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
243265001937	Flavodoxin; Region: Flavodoxin_1; pfam00258
243265001938	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
243265001939	FAD binding pocket [chemical binding]; other site
243265001940	FAD binding motif [chemical binding]; other site
243265001941	catalytic residues [active]
243265001942	NAD binding pocket [chemical binding]; other site
243265001943	phosphate binding motif [ion binding]; other site
243265001944	beta-alpha-beta structure motif; other site
243265001945	sulfite reductase subunit beta; Provisional; Region: PRK13504
243265001946	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
243265001947	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
243265001948	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
243265001949	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
243265001950	Active Sites [active]
243265001951	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
243265001952	HicB family; Region: HicB; pfam05534
243265001953	siroheme synthase; Provisional; Region: cysG; PRK10637
243265001954	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
243265001955	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
243265001956	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
243265001957	active site
243265001958	SAM binding site [chemical binding]; other site
243265001959	homodimer interface [polypeptide binding]; other site
243265001960	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
243265001961	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
243265001962	Active Sites [active]
243265001963	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
243265001964	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
243265001965	CysD dimerization site [polypeptide binding]; other site
243265001966	G1 box; other site
243265001967	putative GEF interaction site [polypeptide binding]; other site
243265001968	GTP/Mg2+ binding site [chemical binding]; other site
243265001969	Switch I region; other site
243265001970	G2 box; other site
243265001971	G3 box; other site
243265001972	Switch II region; other site
243265001973	G4 box; other site
243265001974	G5 box; other site
243265001975	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
243265001976	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
243265001977	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
243265001978	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
243265001979	ligand-binding site [chemical binding]; other site
243265001980	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
243265001981	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
243265001982	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
243265001983	substrate binding site; other site
243265001984	dimer interface; other site
243265001985	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
243265001986	homotrimer interaction site [polypeptide binding]; other site
243265001987	zinc binding site [ion binding]; other site
243265001988	CDP-binding sites; other site
243265001989	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
243265001990	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
243265001991	Permutation of conserved domain; other site
243265001992	active site
243265001993	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
243265001994	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
243265001995	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
243265001996	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265001997	S-adenosylmethionine binding site [chemical binding]; other site
243265001998	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
243265001999	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
243265002000	Peptidase family M23; Region: Peptidase_M23; pfam01551
243265002001	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
243265002002	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
243265002003	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265002004	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
243265002005	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265002006	DNA binding residues [nucleotide binding]
243265002007	Homeodomain-like domain; Region: HTH_23; pfam13384
243265002008	Winged helix-turn helix; Region: HTH_29; pfam13551
243265002009	Winged helix-turn helix; Region: HTH_33; pfam13592
243265002010	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265002011	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265002012	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
243265002013	active site
243265002014	dinuclear metal binding site [ion binding]; other site
243265002015	dimerization interface [polypeptide binding]; other site
243265002016	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
243265002017	MutS domain I; Region: MutS_I; pfam01624
243265002018	MutS domain II; Region: MutS_II; pfam05188
243265002019	MutS domain III; Region: MutS_III; pfam05192
243265002020	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
243265002021	Walker A/P-loop; other site
243265002022	ATP binding site [chemical binding]; other site
243265002023	Q-loop/lid; other site
243265002024	ABC transporter signature motif; other site
243265002025	Walker B; other site
243265002026	D-loop; other site
243265002027	H-loop/switch region; other site
243265002028	Protein of unknwon function (DUF2893); Region: DUF2893; pfam11459
243265002029	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; cl00973
243265002030	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
243265002031	polyol permease family; Region: 2A0118; TIGR00897
243265002032	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002033	putative substrate translocation pore; other site
243265002034	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265002035	Neisseria PilC beta-propeller domain; Region: Neisseria_PilC; pfam05567
243265002036	Homeodomain-like domain; Region: HTH_23; pfam13384
243265002037	Winged helix-turn helix; Region: HTH_29; pfam13551
243265002038	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265002039	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265002040	Secretin and TonB N terminus short domain; Region: STN; smart00965
243265002041	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
243265002042	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
243265002043	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
243265002044	fec operon regulator FecR; Reviewed; Region: PRK09774
243265002045	FecR protein; Region: FecR; pfam04773
243265002046	RNA polymerase sigma factor; Provisional; Region: PRK12528
243265002047	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265002048	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265002049	DNA binding residues [nucleotide binding]
243265002050	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
243265002051	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cl17426
243265002052	folate binding site [chemical binding]; other site
243265002053	NADP+ binding site [chemical binding]; other site
243265002054	Fic/DOC family; Region: Fic; pfam02661
243265002055	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
243265002056	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
243265002057	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
243265002058	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
243265002059	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
243265002060	CT1975-like protein; Region: Cas_CT1975; pfam09344
243265002061	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
243265002062	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
243265002063	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
243265002064	pyridoxal-dependent decarboxylase, exosortase A system-associated; Region: dCO2ase_PEP1; TIGR03099
243265002065	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Btrk Decarboxylase; Region: PLPDE_III_Btrk_like; cd06839
243265002066	dimer interface [polypeptide binding]; other site
243265002067	active site
243265002068	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
243265002069	catalytic residues [active]
243265002070	substrate binding site [chemical binding]; other site
243265002071	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
243265002072	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
243265002073	dimer interface [polypeptide binding]; other site
243265002074	active site
243265002075	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
243265002076	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
243265002077	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
243265002078	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
243265002079	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
243265002080	AMP-binding enzyme; Region: AMP-binding; pfam00501
243265002081	acyl-activating enzyme (AAE) consensus motif; other site
243265002082	AMP binding site [chemical binding]; other site
243265002083	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
243265002084	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
243265002085	dimer interface [polypeptide binding]; other site
243265002086	active site
243265002087	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
243265002088	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
243265002089	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265002090	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
243265002091	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265002092	acyl-activating enzyme (AAE) consensus motif; other site
243265002093	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_6; cd05922
243265002094	acyl-activating enzyme (AAE) consensus motif; other site
243265002095	putative AMP binding site [chemical binding]; other site
243265002096	putative active site [active]
243265002097	putative CoA binding site [chemical binding]; other site
243265002098	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
243265002099	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
243265002100	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
243265002101	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
243265002102	active site
243265002103	Phosphopantetheine attachment site; Region: PP-binding; cl09936
243265002104	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
243265002105	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
243265002106	Int/Topo IB signature motif; other site
243265002107	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265002108	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265002109	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
243265002110	PapC N-terminal domain; Region: PapC_N; pfam13954
243265002111	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
243265002112	PapC C-terminal domain; Region: PapC_C; pfam13953
243265002113	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
243265002114	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265002115	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265002116	Fimbrial protein; Region: Fimbrial; cl01416
243265002117	Fimbrial protein; Region: Fimbrial; pfam00419
243265002118	Fimbrial protein; Region: Fimbrial; cl01416
243265002119	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265002120	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265002121	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265002122	non-specific DNA binding site [nucleotide binding]; other site
243265002123	salt bridge; other site
243265002124	sequence-specific DNA binding site [nucleotide binding]; other site
243265002125	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265002126	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265002127	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265002128	Fimbrial protein; Region: Fimbrial; pfam00419
243265002129	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265002130	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265002131	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265002132	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
243265002133	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265002134	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265002135	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
243265002136	PapC N-terminal domain; Region: PapC_N; pfam13954
243265002137	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
243265002138	PapC C-terminal domain; Region: PapC_C; pfam13953
243265002139	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265002140	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265002141	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265002142	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265002143	Fimbrial protein; Region: Fimbrial; pfam00419
243265002144	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265002145	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265002146	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265002147	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265002148	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265002149	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265002150	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
243265002151	PapC N-terminal domain; Region: PapC_N; pfam13954
243265002152	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
243265002153	PapC C-terminal domain; Region: PapC_C; pfam13953
243265002154	hypothetical protein; Provisional; Region: PRK15301
243265002155	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
243265002156	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
243265002157	nudix motif; other site
243265002158	nudix motif; other site
243265002159	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
243265002160	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
243265002161	GDP-binding site [chemical binding]; other site
243265002162	ACT binding site; other site
243265002163	IMP binding site; other site
243265002164	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
243265002165	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265002166	active site
243265002167	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
243265002168	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
243265002169	catalytic residues [active]
243265002170	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
243265002171	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
243265002172	tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; Region: tnaA; PRK13238
243265002173	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
243265002174	substrate binding site [chemical binding]; other site
243265002175	tetramer interface [polypeptide binding]; other site
243265002176	catalytic residue [active]
243265002177	tryptophan permease; Provisional; Region: PRK10483
243265002178	aromatic amino acid transport protein; Region: araaP; TIGR00837
243265002179	hypothetical protein; Provisional; Region: PRK02399
243265002180	Uncharacterized protein family (UPF0261); Region: UPF0261; pfam06792
243265002181	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
243265002182	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
243265002183	DNA-binding interface [nucleotide binding]; DNA binding site
243265002184	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
243265002185	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
243265002186	tetramer interface [polypeptide binding]; other site
243265002187	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265002188	catalytic residue [active]
243265002189	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
243265002190	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
243265002191	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
243265002192	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
243265002193	non-specific DNA binding site [nucleotide binding]; other site
243265002194	salt bridge; other site
243265002195	sequence-specific DNA binding site [nucleotide binding]; other site
243265002196	ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432
243265002197	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
243265002198	Walker A/P-loop; other site
243265002199	ATP binding site [chemical binding]; other site
243265002200	Q-loop/lid; other site
243265002201	ABC transporter signature motif; other site
243265002202	Walker B; other site
243265002203	D-loop; other site
243265002204	H-loop/switch region; other site
243265002205	TOBE domain; Region: TOBE_2; pfam08402
243265002206	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
243265002207	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265002208	dimer interface [polypeptide binding]; other site
243265002209	conserved gate region; other site
243265002210	putative PBP binding loops; other site
243265002211	ABC-ATPase subunit interface; other site
243265002212	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265002213	dimer interface [polypeptide binding]; other site
243265002214	conserved gate region; other site
243265002215	putative PBP binding loops; other site
243265002216	ABC-ATPase subunit interface; other site
243265002217	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
243265002218	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
243265002219	regulatory protein UhpC; Provisional; Region: PRK11663
243265002220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002221	putative substrate translocation pore; other site
243265002222	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
243265002223	MASE1; Region: MASE1; pfam05231
243265002224	Histidine kinase; Region: HisKA_3; pfam07730
243265002225	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265002226	ATP binding site [chemical binding]; other site
243265002227	Mg2+ binding site [ion binding]; other site
243265002228	G-X-G motif; other site
243265002229	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002230	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265002231	active site
243265002232	phosphorylation site [posttranslational modification]
243265002233	intermolecular recognition site; other site
243265002234	dimerization interface [polypeptide binding]; other site
243265002235	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002236	DNA binding residues [nucleotide binding]
243265002237	dimerization interface [polypeptide binding]; other site
243265002238	PAAR motif; Region: PAAR_motif; pfam05488
243265002239	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
243265002240	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
243265002241	This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990
243265002242	Truncated gene. Highly similar in N terminal to VgrG and VgrE related protein of Photorhabdus
243265002243	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
243265002244	active site
243265002245	conformational flexibility of ligand binding pocket; other site
243265002246	ADP-ribosylating toxin turn-turn motif; other site
243265002247	Truncated gene. Some high similarities with gp31 related protein of Photorhabdus luminescens
243265002248	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
243265002249	This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990
243265002250	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
243265002251	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265002252	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265002253	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733
243265002254	Tir chaperone protein (CesT) family; Region: CesT; cl08444
243265002255	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cd00741
243265002256	nucleophilic elbow; other site
243265002257	catalytic triad; other site
243265002258	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
243265002259	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
243265002260	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
243265002261	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
243265002262	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
243265002263	Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; pfam08013
243265002264	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
243265002265	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
243265002266	dimer interface [polypeptide binding]; other site
243265002267	active site
243265002268	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
243265002269	putative active site [active]
243265002270	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
243265002271	active site
243265002272	phosphorylation site [posttranslational modification]
243265002273	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
243265002274	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
243265002275	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
243265002276	active pocket/dimerization site; other site
243265002277	active site
243265002278	phosphorylation site [posttranslational modification]
243265002279	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
243265002280	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
243265002281	intersubunit interface [polypeptide binding]; other site
243265002282	active site
243265002283	zinc binding site [ion binding]; other site
243265002284	Na+ binding site [ion binding]; other site
243265002285	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
243265002286	Isochorismatase family; Region: Isochorismatase; pfam00857
243265002287	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
243265002288	catalytic triad [active]
243265002289	conserved cis-peptide bond; other site
243265002290	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
243265002291	spermidine synthase; Provisional; Region: PRK00811
243265002292	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265002293	S-adenosylmethionine binding site [chemical binding]; other site
243265002294	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
243265002295	multicopper oxidase; Provisional; Region: PRK10965
243265002296	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
243265002297	Multicopper oxidase; Region: Cu-oxidase; pfam00394
243265002298	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
243265002299	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
243265002300	Probable truncated integrase
243265002301	Truncated gene. Weakly similar to  integrase
243265002302	Winged helix-turn helix; Region: HTH_29; pfam13551
243265002303	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
243265002304	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
243265002305	putative active site [active]
243265002306	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265002307	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
243265002308	Walker A/P-loop; other site
243265002309	ATP binding site [chemical binding]; other site
243265002310	Q-loop/lid; other site
243265002311	ABC transporter signature motif; other site
243265002312	Walker B; other site
243265002313	D-loop; other site
243265002314	H-loop/switch region; other site
243265002315	Truncated gene. Similar to C-terminal region of colicin V secretion protein
243265002316	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
243265002317	Helix-turn-helix domain; Region: HTH_38; pfam13936
243265002318	Homeodomain-like domain; Region: HTH_32; pfam13565
243265002319	Integrase core domain; Region: rve; pfam00665
243265002320	Truncated gene. Similar to N-terminal region of colicin V secretion protein
243265002321	Cupin superfamily protein; Region: Cupin_4; pfam08007
243265002322	Cupin-like domain; Region: Cupin_8; pfam13621
243265002323	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265002324	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265002325	active site
243265002326	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
243265002327	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265002328	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
243265002329	Coenzyme A binding pocket [chemical binding]; other site
243265002330	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
243265002331	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265002332	active site
243265002333	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
243265002334	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265002335	salt bridge; other site
243265002336	non-specific DNA binding site [nucleotide binding]; other site
243265002337	sequence-specific DNA binding site [nucleotide binding]; other site
243265002338	Plasmid maintenance system killer protein; Region: Plasmid_killer; pfam05015
243265002339	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
243265002340	active site clefts [active]
243265002341	zinc binding site [ion binding]; other site
243265002342	dimer interface [polypeptide binding]; other site
243265002343	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
243265002344	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
243265002345	Walker A/P-loop; other site
243265002346	ATP binding site [chemical binding]; other site
243265002347	Q-loop/lid; other site
243265002348	ABC transporter signature motif; other site
243265002349	Walker B; other site
243265002350	D-loop; other site
243265002351	H-loop/switch region; other site
243265002352	inner membrane transport permease; Provisional; Region: PRK15066
243265002353	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
243265002354	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
243265002355	tetramerization interface [polypeptide binding]; other site
243265002356	active site
243265002357	Pantoate-beta-alanine ligase; Region: PanC; cd00560
243265002358	pantoate--beta-alanine ligase; Region: panC; TIGR00018
243265002359	active site
243265002360	ATP-binding site [chemical binding]; other site
243265002361	pantoate-binding site; other site
243265002362	HXXH motif; other site
243265002363	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
243265002364	oligomerization interface [polypeptide binding]; other site
243265002365	active site
243265002366	metal binding site [ion binding]; metal-binding site
243265002367	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
243265002368	catalytic center binding site [active]
243265002369	ATP binding site [chemical binding]; other site
243265002370	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
243265002371	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
243265002372	active site
243265002373	NTP binding site [chemical binding]; other site
243265002374	metal binding triad [ion binding]; metal-binding site
243265002375	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
243265002376	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
243265002377	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
243265002378	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
243265002379	active site
243265002380	HIGH motif; other site
243265002381	nucleotide binding site [chemical binding]; other site
243265002382	active site
243265002383	KMSKS motif; other site
243265002384	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
243265002385	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
243265002386	Truncated gene. Weakly similar to  transposase B
243265002387	Uncharacterized conserved protein [Function unknown]; Region: COG1262
243265002388	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
243265002389	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
243265002390	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265002391	ATP binding site [chemical binding]; other site
243265002392	putative Mg++ binding site [ion binding]; other site
243265002393	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265002394	nucleotide binding region [chemical binding]; other site
243265002395	ATP-binding site [chemical binding]; other site
243265002396	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
243265002397	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
243265002398	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
243265002399	Transglycosylase; Region: Transgly; pfam00912
243265002400	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
243265002401	PAAR motif; Region: PAAR_motif; pfam05488
243265002402	S-type Pyocin; Region: Pyocin_S; pfam06958
243265002403	Similar to C-terminal region of klebicin B, pyocin S2 and the killer protein of pyocin S1
243265002404	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
243265002405	Similar to killer protein of pyocin S3
243265002406	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
243265002407	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265002408	non-specific DNA binding site [nucleotide binding]; other site
243265002409	salt bridge; other site
243265002410	sequence-specific DNA binding site [nucleotide binding]; other site
243265002411	HipA N-terminal domain; Region: Couple_hipA; pfam13657
243265002412	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
243265002413	HipA-like N-terminal domain; Region: HipA_N; pfam07805
243265002414	HipA-like C-terminal domain; Region: HipA_C; pfam07804
243265002415	Condensation domain; Region: Condensation; pfam00668
243265002416	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265002417	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265002418	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265002419	acyl-activating enzyme (AAE) consensus motif; other site
243265002420	AMP binding site [chemical binding]; other site
243265002421	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265002422	Condensation domain; Region: Condensation; pfam00668
243265002423	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265002424	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265002425	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265002426	acyl-activating enzyme (AAE) consensus motif; other site
243265002427	AMP binding site [chemical binding]; other site
243265002428	Methyltransferase domain; Region: Methyltransf_31; pfam13847
243265002429	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265002430	S-adenosylmethionine binding site [chemical binding]; other site
243265002431	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265002432	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265002433	Condensation domain; Region: Condensation; pfam00668
243265002434	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265002435	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265002436	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265002437	acyl-activating enzyme (AAE) consensus motif; other site
243265002438	AMP binding site [chemical binding]; other site
243265002439	Methyltransferase domain; Region: Methyltransf_31; pfam13847
243265002440	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265002441	S-adenosylmethionine binding site [chemical binding]; other site
243265002442	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265002443	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265002444	Condensation domain; Region: Condensation; pfam00668
243265002445	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265002446	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265002447	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265002448	non-specific DNA binding site [nucleotide binding]; other site
243265002449	salt bridge; other site
243265002450	sequence-specific DNA binding site [nucleotide binding]; other site
243265002451	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
243265002452	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
243265002453	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265002454	inhibitor-cofactor binding pocket; inhibition site
243265002455	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265002456	catalytic residue [active]
243265002457	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
243265002458	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
243265002459	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
243265002460	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
243265002461	cobalamin binding residues [chemical binding]; other site
243265002462	putative BtuC binding residues; other site
243265002463	dimer interface [polypeptide binding]; other site
243265002464	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
243265002465	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
243265002466	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
243265002467	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
243265002468	Zn2+ binding site [ion binding]; other site
243265002469	Mg2+ binding site [ion binding]; other site
243265002470	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
243265002471	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
243265002472	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
243265002473	dimerization interface [polypeptide binding]; other site
243265002474	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
243265002475	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265002476	dimer interface [polypeptide binding]; other site
243265002477	phosphorylation site [posttranslational modification]
243265002478	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265002479	ATP binding site [chemical binding]; other site
243265002480	Mg2+ binding site [ion binding]; other site
243265002481	G-X-G motif; other site
243265002482	Response regulator receiver domain; Region: Response_reg; pfam00072
243265002483	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265002484	active site
243265002485	phosphorylation site [posttranslational modification]
243265002486	intermolecular recognition site; other site
243265002487	dimerization interface [polypeptide binding]; other site
243265002488	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
243265002489	putative binding surface; other site
243265002490	active site
243265002491	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
243265002492	TRAM domain; Region: TRAM; pfam01938
243265002493	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
243265002494	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265002495	S-adenosylmethionine binding site [chemical binding]; other site
243265002496	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
243265002497	HD domain; Region: HD_4; pfam13328
243265002498	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
243265002499	synthetase active site [active]
243265002500	NTP binding site [chemical binding]; other site
243265002501	metal binding site [ion binding]; metal-binding site
243265002502	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
243265002503	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
243265002504	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
243265002505	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
243265002506	homodimer interface [polypeptide binding]; other site
243265002507	metal binding site [ion binding]; metal-binding site
243265002508	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
243265002509	homodimer interface [polypeptide binding]; other site
243265002510	active site
243265002511	putative chemical substrate binding site [chemical binding]; other site
243265002512	metal binding site [ion binding]; metal-binding site
243265002513	CTP synthetase; Validated; Region: pyrG; PRK05380
243265002514	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
243265002515	Catalytic site [active]
243265002516	active site
243265002517	UTP binding site [chemical binding]; other site
243265002518	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
243265002519	active site
243265002520	putative oxyanion hole; other site
243265002521	catalytic triad [active]
243265002522	enolase; Provisional; Region: eno; PRK00077
243265002523	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
243265002524	dimer interface [polypeptide binding]; other site
243265002525	metal binding site [ion binding]; metal-binding site
243265002526	substrate binding pocket [chemical binding]; other site
243265002527	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
243265002528	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
243265002529	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265002530	catalytic residue [active]
243265002531	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002532	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265002533	putative substrate translocation pore; other site
243265002534	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265002535	PAS fold; Region: PAS_4; pfam08448
243265002536	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002537	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002538	DNA binding residues [nucleotide binding]
243265002539	dimerization interface [polypeptide binding]; other site
243265002540	PAS fold; Region: PAS_4; pfam08448
243265002541	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002542	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002543	DNA binding residues [nucleotide binding]
243265002544	dimerization interface [polypeptide binding]; other site
243265002545	PAS fold; Region: PAS_4; pfam08448
243265002546	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002547	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002548	DNA binding residues [nucleotide binding]
243265002549	dimerization interface [polypeptide binding]; other site
243265002550	PAS fold; Region: PAS_4; pfam08448
243265002551	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002552	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002553	DNA binding residues [nucleotide binding]
243265002554	dimerization interface [polypeptide binding]; other site
243265002555	PAS fold; Region: PAS_4; pfam08448
243265002556	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002557	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002558	DNA binding residues [nucleotide binding]
243265002559	dimerization interface [polypeptide binding]; other site
243265002560	PAS fold; Region: PAS_4; pfam08448
243265002561	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002562	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002563	DNA binding residues [nucleotide binding]
243265002564	dimerization interface [polypeptide binding]; other site
243265002565	PAS fold; Region: PAS_4; pfam08448
243265002566	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002567	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002568	DNA binding residues [nucleotide binding]
243265002569	dimerization interface [polypeptide binding]; other site
243265002570	PAS fold; Region: PAS_4; pfam08448
243265002571	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265002572	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265002573	DNA binding residues [nucleotide binding]
243265002574	dimerization interface [polypeptide binding]; other site
243265002575	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
243265002576	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
243265002577	transmembrane helices; other site
243265002578	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
243265002579	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002580	putative substrate translocation pore; other site
243265002581	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
243265002582	PIN domains of VapC and Smg6 ribonucleases, ribosome assembly factor NOB1, Archaeoglobus fulgidus AF0591 protein and homologs; Region: PIN_VapC-Smg6-like; cd09855
243265002583	putative active site [active]
243265002584	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
243265002585	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
243265002586	metal binding triad [ion binding]; metal-binding site
243265002587	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
243265002588	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
243265002589	active site
243265002590	radical SAM protein, MSMEG_0568 family; Region: rSAM_MSMEG_0568; TIGR04043
243265002591	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
243265002592	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265002593	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
243265002594	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
243265002595	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
243265002596	N-acetyl-D-glucosamine binding site [chemical binding]; other site
243265002597	catalytic residue [active]
243265002598	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
243265002599	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
243265002600	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
243265002601	Methyltransferase domain; Region: Methyltransf_11; pfam08241
243265002602	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
243265002603	RNA/DNA hybrid binding site [nucleotide binding]; other site
243265002604	active site
243265002605	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
243265002606	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
243265002607	active site
243265002608	catalytic site [active]
243265002609	substrate binding site [chemical binding]; other site
243265002610	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265002611	PAS fold; Region: PAS_4; pfam08448
243265002612	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
243265002613	DNA binding residues [nucleotide binding]
243265002614	transketolase; Reviewed; Region: PRK12753
243265002615	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
243265002616	TPP-binding site [chemical binding]; other site
243265002617	dimer interface [polypeptide binding]; other site
243265002618	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
243265002619	PYR/PP interface [polypeptide binding]; other site
243265002620	dimer interface [polypeptide binding]; other site
243265002621	TPP binding site [chemical binding]; other site
243265002622	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
243265002623	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
243265002624	Transcriptional regulators [Transcription]; Region: MarR; COG1846
243265002625	MarR family; Region: MarR_2; pfam12802
243265002626	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
243265002627	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
243265002628	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
243265002629	FAD binding domain; Region: FAD_binding_4; pfam01565
243265002630	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
243265002631	Cupin domain; Region: Cupin_2; cl17218
243265002632	Some similaruties with transporter
243265002633	Weakly similar to probable short-chain dehydrogenase
243265002634	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
243265002635	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
243265002636	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
243265002637	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
243265002638	Phosphoglycerate kinase; Region: PGK; pfam00162
243265002639	substrate binding site [chemical binding]; other site
243265002640	hinge regions; other site
243265002641	ADP binding site [chemical binding]; other site
243265002642	catalytic site [active]
243265002643	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
243265002644	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
243265002645	active site
243265002646	intersubunit interface [polypeptide binding]; other site
243265002647	zinc binding site [ion binding]; other site
243265002648	Na+ binding site [ion binding]; other site
243265002649	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265002650	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
243265002651	Coenzyme A binding pocket [chemical binding]; other site
243265002652	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
243265002653	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265002654	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265002655	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
243265002656	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
243265002657	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
243265002658	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
243265002659	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265002660	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265002661	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265002662	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265002663	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
243265002664	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265002665	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265002666	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265002667	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265002668	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
243265002669	Family description; Region: VCBS; pfam13517
243265002670	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
243265002671	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
243265002672	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
243265002673	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
243265002674	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265002675	S-adenosylmethionine binding site [chemical binding]; other site
243265002676	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
243265002677	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002678	putative substrate translocation pore; other site
243265002679	POT family; Region: PTR2; pfam00854
243265002680	Flavin Reductases; Region: FlaRed; cl00801
243265002681	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
243265002682	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
243265002683	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265002684	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265002685	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
243265002686	classical (c) SDRs; Region: SDR_c; cd05233
243265002687	NAD(P) binding site [chemical binding]; other site
243265002688	active site
243265002689	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
243265002690	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
243265002691	Cupin domain; Region: Cupin_2; cl17218
243265002692	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265002693	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002694	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
243265002695	putative substrate translocation pore; other site
243265002696	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
243265002697	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
243265002698	succinic semialdehyde dehydrogenase; Region: PLN02278
243265002699	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
243265002700	tetramerization interface [polypeptide binding]; other site
243265002701	NAD(P) binding site [chemical binding]; other site
243265002702	catalytic residues [active]
243265002703	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002704	putative substrate translocation pore; other site
243265002705	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
243265002706	putative substrate binding pocket [chemical binding]; other site
243265002707	trimer interface [polypeptide binding]; other site
243265002708	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
243265002709	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
243265002710	putative active site [active]
243265002711	putative metal binding site [ion binding]; other site
243265002712	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
243265002713	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
243265002714	NAD binding site [chemical binding]; other site
243265002715	catalytic residues [active]
243265002716	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
243265002717	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
243265002718	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
243265002719	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
243265002720	Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977
243265002721	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
243265002722	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265002723	Fimbrial protein; Region: Fimbrial; cl01416
243265002724	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
243265002725	PapC N-terminal domain; Region: PapC_N; pfam13954
243265002726	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
243265002727	PapC C-terminal domain; Region: PapC_C; pfam13953
243265002728	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265002729	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265002730	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265002731	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265002732	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
243265002733	Cupin domain; Region: Cupin_2; pfam07883
243265002734	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
243265002735	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
243265002736	iron-sulfur cluster [ion binding]; other site
243265002737	[2Fe-2S] cluster binding site [ion binding]; other site
243265002738	C-terminal catalytic domain of the large/alpha subunit (ahdA1c) of a ring-hydroxylating dioxygenase from Sphingomonas sp. strain P2 and related proteins; Region: RHO_alpha_C_ahdA1c-like; cd08880
243265002739	putative alpha subunit interface [polypeptide binding]; other site
243265002740	putative active site [active]
243265002741	putative substrate binding site [chemical binding]; other site
243265002742	Fe binding site [ion binding]; other site
243265002743	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
243265002744	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
243265002745	CoA-transferase family III; Region: CoA_transf_3; pfam02515
243265002746	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002747	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
243265002748	putative substrate translocation pore; other site
243265002749	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
243265002750	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
243265002751	benzoate transport; Region: 2A0115; TIGR00895
243265002752	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265002753	putative substrate translocation pore; other site
243265002754	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
243265002755	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
243265002756	TIM-barrel signal transduction protein; Region: TIM-br_sig_trns; pfam09370
243265002757	hypothetical protein; Provisional; Region: PRK02399
243265002758	Uncharacterized protein family (UPF0261); Region: UPF0261; pfam06792
243265002759	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
243265002760	Truncated gene. Some high similarities with Unknown protein
243265002761	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265002762	non-specific DNA binding site [nucleotide binding]; other site
243265002763	salt bridge; other site
243265002764	sequence-specific DNA binding site [nucleotide binding]; other site
243265002765	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
243265002766	Truncated gene. Some similarities with Unknown protein
243265002767	Truncated gene. Some similarities with C-terminal region of RetA protein
243265002768	Truncated gene. Similar to central region of RetA protein
243265002769	Truncated gene. Some similarities with N-terminal region of RetA protein
243265002770	Transposase; Region: HTH_Tnp_1; cl17663
243265002771	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
243265002772	Transposase; Region: HTH_Tnp_1; pfam01527
243265002773	HTH-like domain; Region: HTH_21; pfam13276
243265002774	Integrase core domain; Region: rve; pfam00665
243265002775	Integrase core domain; Region: rve_3; cl15866
243265002776	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
243265002777	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
243265002778	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
243265002779	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
243265002780	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
243265002781	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
243265002782	active site
243265002783	catalytic residues [active]
243265002784	DNA binding site [nucleotide binding]
243265002785	Int/Topo IB signature motif; other site
243265002786	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
243265002787	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
243265002788	P-loop; other site
243265002789	Magnesium ion binding site [ion binding]; other site
243265002790	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
243265002791	replicative DNA helicase; Region: DnaB; TIGR00665
243265002792	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
243265002793	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
243265002794	Walker A motif; other site
243265002795	ATP binding site [chemical binding]; other site
243265002796	Walker B motif; other site
243265002797	DNA binding loops [nucleotide binding]
243265002798	integrating conjugative element, PFGI_1 class, ParB family protein; Region: ICE_PFGI_1_parB; TIGR03764
243265002799	ParB-like nuclease domain; Region: ParBc; pfam02195
243265002800	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
243265002801	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
243265002802	integrating conjugative element protein, PFL_4669 family; Region: ICE_PFL4669; TIGR03761
243265002803	DNA topoisomerase III; Provisional; Region: PRK07726
243265002804	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
243265002805	active site
243265002806	putative interdomain interaction site [polypeptide binding]; other site
243265002807	putative metal-binding site [ion binding]; other site
243265002808	putative nucleotide binding site [chemical binding]; other site
243265002809	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
243265002810	domain I; other site
243265002811	DNA binding groove [nucleotide binding]
243265002812	phosphate binding site [ion binding]; other site
243265002813	domain II; other site
243265002814	domain III; other site
243265002815	nucleotide binding site [chemical binding]; other site
243265002816	catalytic site [active]
243265002817	domain IV; other site
243265002818	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
243265002819	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
243265002820	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
243265002821	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
243265002822	dimer interface [polypeptide binding]; other site
243265002823	ssDNA binding site [nucleotide binding]; other site
243265002824	tetramer (dimer of dimers) interface [polypeptide binding]; other site
243265002825	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
243265002826	active site
243265002827	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
243265002828	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
243265002829	Protein of unknown function (DUF1162); Region: DUF1162; pfam06650
243265002830	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
243265002831	Abi-like protein; Region: Abi_2; pfam07751
243265002832	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
243265002833	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
243265002834	PilM; Region: PilM; pfam07419
243265002835	type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520
243265002836	Secretin N-terminal domain; Region: Secretin_N_2; pfam07655
243265002837	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
243265002838	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
243265002839	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
243265002840	Type II/IV secretion system protein; Region: T2SE; pfam00437
243265002841	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
243265002842	Walker A motif; other site
243265002843	ATP binding site [chemical binding]; other site
243265002844	Walker B motif; other site
243265002845	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
243265002846	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
243265002847	PilS N terminal; Region: PilS; pfam08805
243265002848	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
243265002849	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
243265002850	Transposase; Region: HTH_Tnp_1; cl17663
243265002851	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
243265002852	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265002853	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
243265002854	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265002855	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
243265002856	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
243265002857	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
243265002858	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
243265002859	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
243265002860	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
243265002861	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
243265002862	N-acetyl-D-glucosamine binding site [chemical binding]; other site
243265002863	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
243265002864	Similar to N terminal part of Unknown protein
243265002865	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265002866	Similar to C terminal part of Unknown protein
243265002867	integrating conjugative element membrane protein, PFL_4697 family; Region: conj_TIGR03747
243265002868	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
243265002869	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
243265002870	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
243265002871	Truncated gene. Similar to C-terminal part of transposon resolvase
243265002872	Truncated gene. Similar to N-terminal part of transposon resolvase
243265002873	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
243265002874	Protein of unknown function (DUF3262); Region: DUF3262; pfam11660
243265002875	integrating conjugative element membrane protein, PFL_4702 family; Region: conj_TIGR03745
243265002876	conjugative transfer region protein, TIGR03750 family; Region: conj_TIGR03750
243265002877	Protein of unknown function (DUF3438); Region: DUF3438; pfam11920
243265002878	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
243265002879	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
243265002880	conjugative transfer ATPase, PFL_4706 family; Region: traC_PFL_4706; TIGR03744
243265002881	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
243265002882	integrating conjugative element protein, PFL_4709 family; Region: conj_TIGR03757
243265002883	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
243265002884	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
243265002885	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
243265002886	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
243265002887	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265002889	Truncated gene. Some similarities with transposase, IS21 family
243265002890	Truncated gene. Some similarities with transposase, IS21 family
243265002891	Truncated gene. Some similarities with peptide synthetase
243265002892	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
243265002893	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
243265002894	active site
243265002895	metal binding site [ion binding]; metal-binding site
243265002896	aminotransferase A; Validated; Region: PRK07683
243265002897	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265002898	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265002899	homodimer interface [polypeptide binding]; other site
243265002900	catalytic residue [active]
243265002901	glycolate oxidase; Region: PLN02535
243265002902	Mandelate dehydrogenase (MDH)-like FMN-binding domain.  MDH is part of a widespread family of homologous FMN-dependent a-hydroxy acid oxidizing enzymes that oxidizes (S)-mandelate to phenylglyoxalate. MDH is an enzyme in the mandelate pathway that occurs...; Region: MDH_FMN; cd04736
243265002903	active site
243265002904	substrate binding site [chemical binding]; other site
243265002905	FMN binding site [chemical binding]; other site
243265002906	catalytic residues [active]
243265002907	Truncated transposase, IS5 Familly
243265002908	Truncated gene. Some similarities with N-terminal part of RetA protein
243265002909	Truncated gene. Similar to central part of RetA protein
243265002910	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
243265002911	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
243265002912	putative active site [active]
243265002913	putative NTP binding site [chemical binding]; other site
243265002914	putative nucleic acid binding site [nucleotide binding]; other site
243265002915	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
243265002916	Truncated gene. Some similarities with C-terminal part of RetA protein
243265002917	Truncated gene. Similar to peptide synthetase
243265002918	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265002919	Truncated gene. Similar to peptide synthetase
243265002920	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265002921	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265002922	Truncated gene. Similar to C terminal part of peptide synthetase
243265002923	Truncated gene. Some similarities with hypothetical proteins encoded in ISEc8
243265002924	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
243265002925	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265002926	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265002927	active site
243265002928	Int/Topo IB signature motif; other site
243265002929	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265002930	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265002931	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265002932	interdomain interaction site; other site
243265002933	active site
243265002934	metal binding site [ion binding]; metal-binding site
243265002935	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265002936	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265002937	non-specific DNA binding site [nucleotide binding]; other site
243265002938	salt bridge; other site
243265002939	sequence-specific DNA binding site [nucleotide binding]; other site
243265002940	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265002941	flagellar biosynthesis regulatory protein FlaF; Reviewed; Region: flaF; PRK12793
243265002942	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265002943	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265002944	active site
243265002945	Int/Topo IB signature motif; other site
243265002946	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265002947	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265002948	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265002949	interdomain interaction site; other site
243265002950	active site
243265002951	metal binding site [ion binding]; metal-binding site
243265002952	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265002953	non-specific DNA binding site [nucleotide binding]; other site
243265002954	salt bridge; other site
243265002955	sequence-specific DNA binding site [nucleotide binding]; other site
243265002956	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265002957	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
243265002958	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
243265002959	A nuclease of the HNH/ENDO VII superfamily with conserved LHH; Region: LHH; pfam14411
243265002960	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265002961	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265002962	active site
243265002963	Int/Topo IB signature motif; other site
243265002964	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265002965	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265002966	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265002967	interdomain interaction site; other site
243265002968	active site
243265002969	metal binding site [ion binding]; metal-binding site
243265002970	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265002971	non-specific DNA binding site [nucleotide binding]; other site
243265002972	salt bridge; other site
243265002973	sequence-specific DNA binding site [nucleotide binding]; other site
243265002974	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265002975	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
243265002976	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
243265002977	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265002978	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
243265002979	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265002980	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265002981	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265002982	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
243265002983	A nuclease of the HNH/ENDO VII superfamily with conserved LHH; Region: LHH; pfam14411
243265002984	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
243265002985	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
243265002986	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
243265002987	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
243265002988	Integrase; Region: Integrase_1; pfam12835
243265002989	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
243265002990	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
243265002991	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
243265002992	Protein of unknown function (DUF3085); Region: DUF3085; pfam11284
243265002993	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
243265002994	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
243265002995	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
243265002996	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
243265002997	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
243265002998	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
243265002999	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
243265003000	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
243265003001	active site
243265003002	catalytic residues [active]
243265003003	DNA binding site [nucleotide binding]
243265003004	Int/Topo IB signature motif; other site
243265003005	murein transglycosylase C; Provisional; Region: mltC; PRK11671
243265003006	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
243265003007	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
243265003008	N-acetyl-D-glucosamine binding site [chemical binding]; other site
243265003009	catalytic residue [active]
243265003010	oxidative damage protection protein; Provisional; Region: PRK05408
243265003011	adenine DNA glycosylase; Provisional; Region: PRK10880
243265003012	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
243265003013	minor groove reading motif; other site
243265003014	helix-hairpin-helix signature motif; other site
243265003015	substrate binding pocket [chemical binding]; other site
243265003016	active site
243265003017	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
243265003018	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
243265003019	DNA binding and oxoG recognition site [nucleotide binding]
243265003020	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
243265003021	hypothetical protein; Provisional; Region: PRK11702
243265003022	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
243265003023	glutaminase; Provisional; Region: PRK00971
243265003024	hypothetical protein; Provisional; Region: PRK10626
243265003025	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
243265003026	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
243265003027	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
243265003028	putative ligand binding residues [chemical binding]; other site
243265003029	HemN family oxidoreductase; Provisional; Region: PRK05660
243265003030	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265003031	FeS/SAM binding site; other site
243265003032	HemN C-terminal domain; Region: HemN_C; pfam06969
243265003033	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
243265003034	active site
243265003035	dimerization interface [polypeptide binding]; other site
243265003036	YGGT family; Region: YGGT; pfam02325
243265003037	YGGT family; Region: YGGT; pfam02325
243265003038	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
243265003039	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
243265003040	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
243265003041	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
243265003042	catalytic residue [active]
243265003043	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
243265003044	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
243265003045	Walker A motif; other site
243265003046	ATP binding site [chemical binding]; other site
243265003047	Walker B motif; other site
243265003048	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
243265003049	hypothetical protein; Validated; Region: PRK00228
243265003050	glutathione synthetase; Provisional; Region: PRK05246
243265003051	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
243265003052	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
243265003053	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
243265003054	RNA methyltransferase, RsmE family; Region: TIGR00046
243265003055	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
243265003056	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
243265003057	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
243265003058	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
243265003059	catalytic residues [active]
243265003060	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
243265003061	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265003062	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265003063	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
243265003064	putative effector binding pocket; other site
243265003065	dimerization interface [polypeptide binding]; other site
243265003066	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
243265003067	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265003068	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
243265003069	dimerization interface [polypeptide binding]; other site
243265003070	diaminopimelate decarboxylase; Provisional; Region: PRK11165
243265003071	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
243265003072	active site
243265003073	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
243265003074	substrate binding site [chemical binding]; other site
243265003075	catalytic residues [active]
243265003076	dimer interface [polypeptide binding]; other site
243265003077	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
243265003078	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
243265003079	active site
243265003080	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
243265003081	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
243265003082	dimer interface [polypeptide binding]; other site
243265003083	active site
243265003084	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
243265003085	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
243265003086	putative active site [active]
243265003087	putative dimer interface [polypeptide binding]; other site
243265003088	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
243265003089	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
243265003090	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
243265003091	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
243265003092	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
243265003093	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
243265003094	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
243265003095	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
243265003096	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
243265003097	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
243265003098	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
243265003099	catalytic loop [active]
243265003100	iron binding site [ion binding]; other site
243265003101	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
243265003102	FAD binding pocket [chemical binding]; other site
243265003103	FAD binding motif [chemical binding]; other site
243265003104	phosphate binding motif [ion binding]; other site
243265003105	beta-alpha-beta structure motif; other site
243265003106	NAD binding pocket [chemical binding]; other site
243265003107	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
243265003108	ApbE family; Region: ApbE; pfam02424
243265003109	Protein of unknown function (DUF539); Region: DUF539; cl01129
243265003110	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
243265003111	KilA-N domain; Region: KilA-N; pfam04383
243265003112	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
243265003113	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
243265003114	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
243265003115	Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668
243265003116	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265003117	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265003118	acyl-activating enzyme (AAE) consensus motif; other site
243265003119	AMP binding site [chemical binding]; other site
243265003120	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265003121	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
243265003122	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
243265003123	active site
243265003124	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265003125	Condensation domain; Region: Condensation; pfam00668
243265003126	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265003127	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265003128	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265003129	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265003130	acyl-activating enzyme (AAE) consensus motif; other site
243265003131	AMP binding site [chemical binding]; other site
243265003132	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265003133	Condensation domain; Region: Condensation; pfam00668
243265003134	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
243265003135	Condensation domain; Region: Condensation; pfam00668
243265003136	non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261
243265003137	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
243265003138	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265003139	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265003140	Walker A/P-loop; other site
243265003141	ATP binding site [chemical binding]; other site
243265003142	Q-loop/lid; other site
243265003143	ABC transporter signature motif; other site
243265003144	Walker B; other site
243265003145	D-loop; other site
243265003146	H-loop/switch region; other site
243265003147	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
243265003148	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265003149	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265003150	Walker A/P-loop; other site
243265003151	ATP binding site [chemical binding]; other site
243265003152	Q-loop/lid; other site
243265003153	ABC transporter signature motif; other site
243265003154	Walker B; other site
243265003155	D-loop; other site
243265003156	H-loop/switch region; other site
243265003157	MbtH-like protein; Region: MbtH; pfam03621
243265003158	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
243265003159	MbtH-like protein; Region: MbtH; cl01279
243265003160	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265003161	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
243265003162	Cytochrome P450; Region: p450; cl12078
243265003163	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265003164	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265003165	acyl-activating enzyme (AAE) consensus motif; other site
243265003166	AMP binding site [chemical binding]; other site
243265003167	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265003168	Condensation domain; Region: Condensation; pfam00668
243265003169	Truncated gene. Some similarities with diaminobutyrate--pyruvate aminotransferase
243265003170	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
243265003171	Transposase; Region: DEDD_Tnp_IS110; pfam01548
243265003172	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
243265003173	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265003174	non-specific DNA binding site [nucleotide binding]; other site
243265003175	sequence-specific DNA binding site [nucleotide binding]; other site
243265003176	salt bridge; other site
243265003177	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
243265003178	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
243265003179	Transposase; Region: DEDD_Tnp_IS110; pfam01548
243265003180	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
243265003181	flavin-dependent oxidoreductase, MSMEG_0569 family; Region: MSMEG_0569_nitr; TIGR04046
243265003182	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
243265003183	MSMEG_0570 family protein; Region: MSMEG_0570_fam; TIGR04042
243265003184	AIR synthase-related protein, sll0787 family; Region: AIR_rel_sll0787; TIGR04049
243265003185	AIR synthase (PurM) related protein, subgroup 3 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two...; Region: PurM-like3; cd02192
243265003186	dimerization interface [polypeptide binding]; other site
243265003187	putative ATP binding site [chemical binding]; other site
243265003188	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265003189	Coenzyme A binding pocket [chemical binding]; other site
243265003190	radical SAM protein, MSMEG_0568 family; Region: rSAM_MSMEG_0568; TIGR04043
243265003191	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265003192	FeS/SAM binding site; other site
243265003193	Predicted amidohydrolase [General function prediction only]; Region: COG0388
243265003194	Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564
243265003195	putative active site [active]
243265003196	catalytic triad [active]
243265003197	putative dimer interface [polypeptide binding]; other site
243265003198	MSMEG_0572 family protein; Region: MSMEG_0572_fam; TIGR04044
243265003199	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
243265003200	PAS domain; Region: PAS_9; pfam13426
243265003201	putative active site [active]
243265003202	heme pocket [chemical binding]; other site
243265003203	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
243265003204	PAS domain; Region: PAS_9; pfam13426
243265003205	putative active site [active]
243265003206	heme pocket [chemical binding]; other site
243265003207	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265003208	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
243265003209	Walker A motif; other site
243265003210	ATP binding site [chemical binding]; other site
243265003211	Walker B motif; other site
243265003212	arginine finger; other site
243265003213	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
243265003214	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial protein Rv2277c and similar proteins; Region: GDPD_Rv2277c_like; cd08580
243265003215	putative active site [active]
243265003216	catalytic site [active]
243265003217	putative metal binding site [ion binding]; other site
243265003218	RNA polymerase sigma factor; Provisional; Region: PRK12528
243265003219	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265003220	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265003221	DNA binding residues [nucleotide binding]
243265003222	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
243265003223	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
243265003224	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265003225	N-terminal plug; other site
243265003226	ligand-binding site [chemical binding]; other site
243265003227	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
243265003228	active site
243265003229	DNA polymerase IV; Validated; Region: PRK02406
243265003230	DNA binding site [nucleotide binding]
243265003231	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
243265003232	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
243265003233	metal binding site [ion binding]; metal-binding site
243265003234	dimer interface [polypeptide binding]; other site
243265003235	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265003236	active site
243265003237	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
243265003238	gamma-glutamyl kinase; Provisional; Region: PRK05429
243265003239	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
243265003240	nucleotide binding site [chemical binding]; other site
243265003241	homotetrameric interface [polypeptide binding]; other site
243265003242	putative phosphate binding site [ion binding]; other site
243265003243	putative allosteric binding site; other site
243265003244	PUA domain; Region: PUA; pfam01472
243265003245	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
243265003246	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
243265003247	putative catalytic cysteine [active]
243265003248	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
243265003249	Shikimate kinase; Region: SKI; pfam01202
243265003250	ADP binding site [chemical binding]; other site
243265003251	magnesium binding site [ion binding]; other site
243265003252	putative shikimate binding site; other site
243265003253	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
243265003254	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
243265003255	putative acyl-acceptor binding pocket; other site
243265003256	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265003257	AMP-binding enzyme; Region: AMP-binding; pfam00501
243265003258	acyl-activating enzyme (AAE) consensus motif; other site
243265003259	active site
243265003260	AMP binding site [chemical binding]; other site
243265003261	CoA binding site [chemical binding]; other site
243265003262	lysophospholipid transporter LplT; Provisional; Region: PRK11195
243265003263	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265003264	putative substrate translocation pore; other site
243265003265	hypothetical protein; Validated; Region: PRK03661
243265003266	recombinase A; Provisional; Region: recA; PRK09354
243265003267	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
243265003268	hexamer interface [polypeptide binding]; other site
243265003269	Walker A motif; other site
243265003270	ATP binding site [chemical binding]; other site
243265003271	Walker B motif; other site
243265003272	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
243265003273	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
243265003274	motif 1; other site
243265003275	active site
243265003276	motif 2; other site
243265003277	motif 3; other site
243265003278	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
243265003279	DHHA1 domain; Region: DHHA1; pfam02272
243265003280	carbon storage regulator; Provisional; Region: PRK01712
243265003281	glutamate--cysteine ligase; Provisional; Region: PRK02107
243265003282	S-ribosylhomocysteinase; Provisional; Region: PRK02260
243265003283	hypothetical protein; Provisional; Region: PRK11573
243265003284	Domain of unknown function DUF21; Region: DUF21; pfam01595
243265003285	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
243265003286	Transporter associated domain; Region: CorC_HlyC; smart01091
243265003287	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
243265003288	signal recognition particle protein; Provisional; Region: PRK10867
243265003289	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
243265003290	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
243265003291	P loop; other site
243265003292	GTP binding site [chemical binding]; other site
243265003293	Signal peptide binding domain; Region: SRP_SPB; pfam02978
243265003294	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
243265003295	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
243265003296	RimM N-terminal domain; Region: RimM; pfam01782
243265003297	PRC-barrel domain; Region: PRC; pfam05239
243265003298	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
243265003299	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
243265003300	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
243265003301	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
243265003302	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
243265003303	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
243265003304	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
243265003305	Chorismate mutase type II; Region: CM_2; cl00693
243265003306	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
243265003307	prephenate dehydrogenase; Validated; Region: PRK08507
243265003308	H-NS histone family; Region: Histone_HNS; pfam00816
243265003309	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
243265003310	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
243265003311	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
243265003312	Prephenate dehydratase; Region: PDT; pfam00800
243265003313	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
243265003314	putative L-Phe binding site [chemical binding]; other site
243265003315	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
243265003316	30S subunit binding site; other site
243265003317	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
243265003318	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
243265003319	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
243265003320	RNA binding surface [nucleotide binding]; other site
243265003321	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
243265003322	active site
243265003323	hypothetical protein; Provisional; Region: PRK10723
243265003324	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
243265003325	protein disaggregation chaperone; Provisional; Region: PRK10865
243265003326	Clp amino terminal domain; Region: Clp_N; pfam02861
243265003327	Clp amino terminal domain; Region: Clp_N; pfam02861
243265003328	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265003329	Walker A motif; other site
243265003330	ATP binding site [chemical binding]; other site
243265003331	Walker B motif; other site
243265003332	arginine finger; other site
243265003333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265003334	Walker A motif; other site
243265003335	ATP binding site [chemical binding]; other site
243265003336	Walker B motif; other site
243265003337	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
243265003338	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
243265003339	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
243265003340	domain interface [polypeptide binding]; other site
243265003341	putative active site [active]
243265003342	catalytic site [active]
243265003343	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
243265003344	domain interface [polypeptide binding]; other site
243265003345	putative active site [active]
243265003346	catalytic site [active]
243265003347	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
243265003348	CoA binding domain; Region: CoA_binding_2; pfam13380
243265003349	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
243265003350	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
243265003351	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
243265003352	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
243265003353	putative methyltransferase; Provisional; Region: PRK10864
243265003354	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
243265003355	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
243265003356	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
243265003357	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265003358	putative substrate translocation pore; other site
243265003359	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265003360	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
243265003361	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265003362	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265003363	transcriptional repressor MprA; Provisional; Region: PRK10870
243265003364	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
243265003365	putative L-valine exporter; Provisional; Region: PRK10408
243265003366	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
243265003367	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
243265003368	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265003369	putative substrate translocation pore; other site
243265003370	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
243265003371	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
243265003372	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
243265003373	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265003374	dimer interface [polypeptide binding]; other site
243265003375	conserved gate region; other site
243265003376	putative PBP binding loops; other site
243265003377	ABC-ATPase subunit interface; other site
243265003378	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
243265003379	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
243265003380	Walker A/P-loop; other site
243265003381	ATP binding site [chemical binding]; other site
243265003382	Q-loop/lid; other site
243265003383	ABC transporter signature motif; other site
243265003384	Walker B; other site
243265003385	D-loop; other site
243265003386	H-loop/switch region; other site
243265003387	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
243265003388	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
243265003389	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
243265003390	dimer interface [polypeptide binding]; other site
243265003391	putative radical transfer pathway; other site
243265003392	diiron center [ion binding]; other site
243265003393	tyrosyl radical; other site
243265003394	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
243265003395	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
243265003396	Class I ribonucleotide reductase; Region: RNR_I; cd01679
243265003397	active site
243265003398	dimer interface [polypeptide binding]; other site
243265003399	catalytic residues [active]
243265003400	effector binding site; other site
243265003401	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
243265003402	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
243265003403	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
243265003404	catalytic residues [active]
243265003405	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
243265003406	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
243265003407	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
243265003408	DNA binding site [nucleotide binding]
243265003409	active site
243265003410	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
243265003411	DNA-binding site [nucleotide binding]; DNA binding site
243265003412	RNA-binding motif; other site
243265003413	chromosome condensation membrane protein; Provisional; Region: PRK14196
243265003414	lipoyl synthase; Provisional; Region: PRK05481
243265003415	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265003416	FeS/SAM binding site; other site
243265003417	lipoate-protein ligase B; Provisional; Region: PRK14342
243265003418	hypothetical protein; Provisional; Region: PRK04998
243265003419	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
243265003420	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
243265003421	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
243265003422	rare lipoprotein A; Provisional; Region: PRK10672
243265003423	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
243265003424	Sporulation related domain; Region: SPOR; pfam05036
243265003425	cell wall shape-determining protein; Provisional; Region: PRK10794
243265003426	penicillin-binding protein 2; Provisional; Region: PRK10795
243265003427	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
243265003428	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
243265003429	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
243265003430	ribosome-associated protein; Provisional; Region: PRK11538
243265003431	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
243265003432	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
243265003433	active site
243265003434	(T/H)XGH motif; other site
243265003435	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
243265003436	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
243265003437	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
243265003438	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
243265003439	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
243265003440	HIGH motif; other site
243265003441	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
243265003442	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
243265003443	active site
243265003444	KMSKS motif; other site
243265003445	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
243265003446	tRNA binding surface [nucleotide binding]; other site
243265003447	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
243265003448	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
243265003449	Walker A/P-loop; other site
243265003450	ATP binding site [chemical binding]; other site
243265003451	Q-loop/lid; other site
243265003452	ABC transporter signature motif; other site
243265003453	Walker B; other site
243265003454	D-loop; other site
243265003455	H-loop/switch region; other site
243265003456	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265003457	dimer interface [polypeptide binding]; other site
243265003458	conserved gate region; other site
243265003459	putative PBP binding loops; other site
243265003460	ABC-ATPase subunit interface; other site
243265003461	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
243265003462	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265003463	dimer interface [polypeptide binding]; other site
243265003464	conserved gate region; other site
243265003465	putative PBP binding loops; other site
243265003466	ABC-ATPase subunit interface; other site
243265003467	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
243265003468	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265003469	substrate binding pocket [chemical binding]; other site
243265003470	membrane-bound complex binding site; other site
243265003471	hinge residues; other site
243265003472	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
243265003473	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
243265003474	putative active site [active]
243265003475	catalytic triad [active]
243265003476	putative dimer interface [polypeptide binding]; other site
243265003477	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
243265003478	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
243265003479	Transporter associated domain; Region: CorC_HlyC; smart01091
243265003480	metal-binding heat shock protein; Provisional; Region: PRK00016
243265003481	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
243265003482	PhoH-like protein; Region: PhoH; pfam02562
243265003483	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
243265003484	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
243265003485	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265003486	FeS/SAM binding site; other site
243265003487	TRAM domain; Region: TRAM; pfam01938
243265003488	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
243265003489	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
243265003490	MarR family; Region: MarR; pfam01047
243265003491	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
243265003492	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
243265003493	nucleotide binding site [chemical binding]; other site
243265003494	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
243265003495	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
243265003496	active site
243265003497	dimer interface [polypeptide binding]; other site
243265003498	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
243265003499	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
243265003500	active site
243265003501	trimer interface [polypeptide binding]; other site
243265003502	allosteric site; other site
243265003503	active site lid [active]
243265003504	hexamer (dimer of trimers) interface [polypeptide binding]; other site
243265003505	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
243265003506	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl17885
243265003507	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
243265003508	active site turn [active]
243265003509	phosphorylation site [posttranslational modification]
243265003510	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
243265003511	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
243265003512	active site
243265003513	HIGH motif; other site
243265003514	nucleotide binding site [chemical binding]; other site
243265003515	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
243265003516	KMSKS motif; other site
243265003517	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
243265003518	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265003519	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265003520	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_7; cd08476
243265003521	putative dimerization interface [polypeptide binding]; other site
243265003522	putative effector binding pocket; other site
243265003523	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
243265003524	hypothetical protein; Provisional; Region: PRK06126
243265003525	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
243265003526	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
243265003527	Cupin domain; Region: Cupin_2; pfam07883
243265003528	Putative carbohydrate binding domain; Region: CHB_HEX; smart01081
243265003529	N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]; Region: Chb; COG3525
243265003530	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
243265003531	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a...; Region: GH20_Sm-chitobiase-like; cd06569
243265003532	active site
243265003533	C-terminal Early set domain associated with the catalytic domain of chitobiase (also called N-acetylglucosaminidase); Region: E_set_Chitobiase_C; cd02847
243265003534	addiction module antitoxin, RelB/DinJ family; Region: RelB_DinJ; TIGR02384
243265003535	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
243265003536	ferric uptake regulator; Provisional; Region: fur; PRK09462
243265003537	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
243265003538	metal binding site 2 [ion binding]; metal-binding site
243265003539	putative DNA binding helix; other site
243265003540	metal binding site 1 [ion binding]; metal-binding site
243265003541	dimer interface [polypeptide binding]; other site
243265003542	structural Zn2+ binding site [ion binding]; other site
243265003543	flavodoxin FldA; Validated; Region: PRK09267
243265003544	LexA regulated protein; Provisional; Region: PRK11675
243265003545	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
243265003546	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
243265003547	conserved cys residue [active]
243265003548	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265003549	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
243265003550	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265003551	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39_likeD; cd02421
243265003552	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
243265003553	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265003554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265003555	Walker A/P-loop; other site
243265003556	ATP binding site [chemical binding]; other site
243265003557	Q-loop/lid; other site
243265003558	ABC transporter signature motif; other site
243265003559	Walker B; other site
243265003560	D-loop; other site
243265003561	H-loop/switch region; other site
243265003562	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
243265003563	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265003564	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
243265003565	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
243265003566	putative active site [active]
243265003567	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265003568	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265003569	Walker A/P-loop; other site
243265003570	ATP binding site [chemical binding]; other site
243265003571	Q-loop/lid; other site
243265003572	ABC transporter signature motif; other site
243265003573	Walker B; other site
243265003574	D-loop; other site
243265003575	H-loop/switch region; other site
243265003576	RTX toxin acyltransferase family; Region: HlyC; cl01131
243265003577	Truncated gene. Highly similar to N-terminal region of RTX toxin RtxA
243265003578	Truncated gene. Highly similar to C-terminal region of RTX toxin RtxA
243265003579	Transposase IS200 like; Region: Y1_Tnp; pfam01797
243265003580	Truncated gene. Highly similar to N-terminal region of RTX toxin RtxA
243265003581	Truncated gene. Highly similar to C-terminal region of RTX toxin RtxA
243265003582	choice-of-anchor C domain; Region: choice_anch_C; TIGR04362
243265003583	Peptidase C80 family; Region: Peptidase_C80; pfam11713
243265003584	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
243265003585	Truncated gene. Similar to N-terminal region of RTX toxin RtxA.
243265003586	Truncated gene. Similar to C-terminal region of RTX toxin RtxA.
243265003587	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
243265003588	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
243265003589	Peptidase C80 family; Region: Peptidase_C80; pfam11713
243265003590	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
243265003591	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265003592	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265003593	Truncated gene. Some similarities with Unknown protein of Photorhabdus
243265003594	Some similarities with Unknown protein of Photorhabdus
243265003595	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265003596	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265003597	active site
243265003598	Int/Topo IB signature motif; other site
243265003599	Truncated gene. Some similarities with C-terminal region of DNA primase
243265003600	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265003601	Truncated gene. Weakly similar to N-terminal region of DNA primase
243265003602	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265003603	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265003604	non-specific DNA binding site [nucleotide binding]; other site
243265003605	salt bridge; other site
243265003606	sequence-specific DNA binding site [nucleotide binding]; other site
243265003607	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265003608	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
243265003609	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265003610	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
243265003611	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265003612	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265003613	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265003614	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
243265003615	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
243265003616	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
243265003617	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
243265003618	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
243265003619	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
243265003620	MG2 domain; Region: A2M_N; pfam01835
243265003621	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
243265003622	surface patch; other site
243265003623	thioester region; other site
243265003624	specificity defining residues; other site
243265003625	penicillin-binding protein 1C; Provisional; Region: PRK11240
243265003626	Transglycosylase; Region: Transgly; pfam00912
243265003627	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
243265003628	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
243265003629	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
243265003630	active site
243265003631	multimer interface [polypeptide binding]; other site
243265003632	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
243265003633	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265003634	FeS/SAM binding site; other site
243265003635	TPR repeat; Region: TPR_11; pfam13414
243265003636	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
243265003637	binding surface
243265003638	TPR motif; other site
243265003639	cytoskeletal protein RodZ; Provisional; Region: PRK10856
243265003640	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265003641	non-specific DNA binding site [nucleotide binding]; other site
243265003642	salt bridge; other site
243265003643	sequence-specific DNA binding site [nucleotide binding]; other site
243265003644	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
243265003645	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
243265003646	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
243265003647	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
243265003648	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
243265003649	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
243265003650	dimer interface [polypeptide binding]; other site
243265003651	motif 1; other site
243265003652	active site
243265003653	motif 2; other site
243265003654	motif 3; other site
243265003655	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
243265003656	anticodon binding site; other site
243265003657	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
243265003658	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
243265003659	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
243265003660	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
243265003661	Trp docking motif [polypeptide binding]; other site
243265003662	GTP-binding protein Der; Reviewed; Region: PRK00093
243265003663	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
243265003664	G1 box; other site
243265003665	GTP/Mg2+ binding site [chemical binding]; other site
243265003666	Switch I region; other site
243265003667	G2 box; other site
243265003668	Switch II region; other site
243265003669	G3 box; other site
243265003670	G4 box; other site
243265003671	G5 box; other site
243265003672	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
243265003673	G1 box; other site
243265003674	GTP/Mg2+ binding site [chemical binding]; other site
243265003675	Switch I region; other site
243265003676	G2 box; other site
243265003677	G3 box; other site
243265003678	Switch II region; other site
243265003679	G4 box; other site
243265003680	G5 box; other site
243265003681	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
243265003682	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
243265003683	active site
243265003684	Zn binding site [ion binding]; other site
243265003685	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
243265003686	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
243265003687	putative acetyltransferase; Provisional; Region: PRK03624
243265003688	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265003689	Coenzyme A binding pocket [chemical binding]; other site
243265003690	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
243265003691	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
243265003692	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
243265003693	thiosulfate transporter subunit; Provisional; Region: PRK10852
243265003694	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
243265003695	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
243265003696	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265003697	dimer interface [polypeptide binding]; other site
243265003698	conserved gate region; other site
243265003699	putative PBP binding loops; other site
243265003700	ABC-ATPase subunit interface; other site
243265003701	sulfate transport protein; Provisional; Region: cysT; CHL00187
243265003702	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265003703	dimer interface [polypeptide binding]; other site
243265003704	conserved gate region; other site
243265003705	putative PBP binding loops; other site
243265003706	ABC-ATPase subunit interface; other site
243265003707	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
243265003708	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
243265003709	Walker A/P-loop; other site
243265003710	ATP binding site [chemical binding]; other site
243265003711	Q-loop/lid; other site
243265003712	ABC transporter signature motif; other site
243265003713	Walker B; other site
243265003714	D-loop; other site
243265003715	H-loop/switch region; other site
243265003716	TOBE-like domain; Region: TOBE_3; pfam12857
243265003717	cysteine synthase B; Region: cysM; TIGR01138
243265003718	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
243265003719	dimer interface [polypeptide binding]; other site
243265003720	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265003721	catalytic residue [active]
243265003722	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
243265003723	HPr interaction site; other site
243265003724	glycerol kinase (GK) interaction site [polypeptide binding]; other site
243265003725	active site
243265003726	phosphorylation site [posttranslational modification]
243265003727	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
243265003728	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
243265003729	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
243265003730	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
243265003731	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
243265003732	dimerization domain swap beta strand [polypeptide binding]; other site
243265003733	regulatory protein interface [polypeptide binding]; other site
243265003734	active site
243265003735	regulatory phosphorylation site [posttranslational modification]; other site
243265003736	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
243265003737	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
243265003738	dimer interface [polypeptide binding]; other site
243265003739	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265003740	catalytic residue [active]
243265003741	putative sulfate transport protein CysZ; Validated; Region: PRK04949
243265003742	cell division protein ZipA; Provisional; Region: PRK03427
243265003743	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
243265003744	FtsZ protein binding site [polypeptide binding]; other site
243265003745	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
243265003746	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
243265003747	nucleotide binding pocket [chemical binding]; other site
243265003748	K-X-D-G motif; other site
243265003749	catalytic site [active]
243265003750	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
243265003751	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
243265003752	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
243265003753	Dimer interface [polypeptide binding]; other site
243265003754	BRCT sequence motif; other site
243265003755	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
243265003756	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
243265003757	Nucleoside recognition; Region: Gate; pfam07670
243265003758	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
243265003759	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
243265003760	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
243265003761	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
243265003762	active site
243265003763	HIGH motif; other site
243265003764	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
243265003765	active site
243265003766	KMSKS motif; other site
243265003767	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265003768	non-specific DNA binding site [nucleotide binding]; other site
243265003769	salt bridge; other site
243265003770	sequence-specific DNA binding site [nucleotide binding]; other site
243265003771	Truncated gene. Some similarities with Unknown protein
243265003772	Truncated gene. Some similarities with Unknown protein
243265003773	glucokinase, proteobacterial type; Region: glk; TIGR00749
243265003774	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
243265003775	nucleotide binding site [chemical binding]; other site
243265003776	replication initiation regulator SeqA; Provisional; Region: PRK11187
243265003777	phosphoglucomutase; Validated; Region: PRK07564
243265003778	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
243265003779	active site
243265003780	substrate binding site [chemical binding]; other site
243265003781	metal binding site [ion binding]; metal-binding site
243265003782	Predicted membrane protein [Function unknown]; Region: COG2510
243265003783	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265003784	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265003785	putative substrate translocation pore; other site
243265003786	ParB-like nuclease domain; Region: ParBc; pfam02195
243265003787	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
243265003788	active site
243265003789	metal-binding site
243265003790	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
243265003791	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265003792	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265003793	homodimer interface [polypeptide binding]; other site
243265003794	catalytic residue [active]
243265003795	Formyltransferase, catalytic core domain; Region: FMT_core; cd08369
243265003796	active site
243265003797	substrate binding site [chemical binding]; other site
243265003798	cosubstrate binding site; other site
243265003799	catalytic site [active]
243265003800	putative hydrolase; Provisional; Region: PRK10976
243265003801	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265003802	active site
243265003803	motif I; other site
243265003804	motif II; other site
243265003805	Domain of unknown function (DUF3369); Region: DUF3369; pfam11849
243265003806	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
243265003807	MAC/Perforin domain; Region: MACPF; cl02616
243265003808	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
243265003809	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265003810	active site
243265003811	phosphorylation site [posttranslational modification]
243265003812	intermolecular recognition site; other site
243265003813	dimerization interface [polypeptide binding]; other site
243265003814	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
243265003815	DNA binding site [nucleotide binding]
243265003816	sensor protein KdpD; Provisional; Region: PRK10490
243265003817	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
243265003818	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
243265003819	Ligand Binding Site [chemical binding]; other site
243265003820	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
243265003821	GAF domain; Region: GAF_3; pfam13492
243265003822	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265003823	dimer interface [polypeptide binding]; other site
243265003824	phosphorylation site [posttranslational modification]
243265003825	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265003826	ATP binding site [chemical binding]; other site
243265003827	Mg2+ binding site [ion binding]; other site
243265003828	G-X-G motif; other site
243265003829	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
243265003830	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
243265003831	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
243265003832	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
243265003833	Homeodomain-like domain; Region: HTH_23; pfam13384
243265003834	Winged helix-turn helix; Region: HTH_29; pfam13551
243265003835	Winged helix-turn helix; Region: HTH_33; pfam13592
243265003836	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265003837	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265003838	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
243265003839	Uncharacterized conserved protein [Function unknown]; Region: COG0327
243265003840	metal-binding protein; Provisional; Region: PRK10799
243265003841	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
243265003842	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
243265003843	dimer interface [polypeptide binding]; other site
243265003844	active site
243265003845	citrylCoA binding site [chemical binding]; other site
243265003846	NADH binding [chemical binding]; other site
243265003847	cationic pore residues; other site
243265003848	oxalacetate/citrate binding site [chemical binding]; other site
243265003849	coenzyme A binding site [chemical binding]; other site
243265003850	catalytic triad [active]
243265003851	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
243265003852	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
243265003853	SdhC subunit interface [polypeptide binding]; other site
243265003854	proximal heme binding site [chemical binding]; other site
243265003855	cardiolipin binding site; other site
243265003856	Iron-sulfur protein interface; other site
243265003857	proximal quinone binding site [chemical binding]; other site
243265003858	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
243265003859	L-aspartate oxidase; Provisional; Region: PRK06175
243265003860	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
243265003861	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
243265003862	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
243265003863	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
243265003864	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
243265003865	TPP-binding site [chemical binding]; other site
243265003866	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
243265003867	dimer interface [polypeptide binding]; other site
243265003868	PYR/PP interface [polypeptide binding]; other site
243265003869	TPP binding site [chemical binding]; other site
243265003870	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
243265003871	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
243265003872	E3 interaction surface; other site
243265003873	lipoyl attachment site [posttranslational modification]; other site
243265003874	e3 binding domain; Region: E3_binding; pfam02817
243265003875	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
243265003876	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
243265003877	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
243265003878	CoA-ligase; Region: Ligase_CoA; pfam00549
243265003879	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
243265003880	CoA binding domain; Region: CoA_binding; smart00881
243265003881	CoA-ligase; Region: Ligase_CoA; pfam00549
243265003882	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
243265003883	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
243265003884	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
243265003885	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
243265003886	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265003887	catalytic residue [active]
243265003888	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
243265003889	FAD-dependent oxidoreductase; Provisional; Region: PRK08132
243265003890	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
243265003891	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
243265003892	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
243265003893	substrate-cofactor binding pocket; other site
243265003894	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265003895	homodimer interface [polypeptide binding]; other site
243265003896	catalytic residue [active]
243265003897	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
243265003898	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265003899	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265003900	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265003901	H+ Antiporter protein; Region: 2A0121; TIGR00900
243265003902	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
243265003903	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265003904	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265003905	homodimer interface [polypeptide binding]; other site
243265003906	catalytic residue [active]
243265003907	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
243265003908	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
243265003909	active site
243265003910	metal binding site [ion binding]; metal-binding site
243265003911	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
243265003912	Truncated gene. Some similarities with Unknown protein of Photorhabdus
243265003913	Truncated gene. Some similarities with Unknown protein of Photorhabdus
243265003914	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
243265003915	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
243265003916	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
243265003917	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
243265003918	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
243265003919	active site
243265003920	colicin uptake protein TolQ; Provisional; Region: PRK10801
243265003921	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
243265003922	colicin uptake protein TolR; Provisional; Region: PRK11024
243265003923	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
243265003924	TolA C-terminal; Region: TolA; pfam06519
243265003925	translocation protein TolB; Provisional; Region: tolB; PRK03629
243265003926	TolB amino-terminal domain; Region: TolB_N; pfam04052
243265003927	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
243265003928	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
243265003929	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
243265003930	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
243265003931	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
243265003932	ligand binding site [chemical binding]; other site
243265003933	tol-pal system protein YbgF; Provisional; Region: PRK10803
243265003934	Tetratricopeptide repeat; Region: TPR_6; pfam13174
243265003935	Tetratricopeptide repeat; Region: TPR_6; pfam13174
243265003936	Streptomycin adenylyltransferase; Region: Adenyl_transf; pfam04439
243265003937	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265003938	Phage Tail Collar Domain; Region: Collar; pfam07484
243265003939	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
243265003940	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265003941	Phage Tail Collar Domain; Region: Collar; pfam07484
243265003942	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265003943	Phage Tail Collar Domain; Region: Collar; pfam07484
243265003944	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
243265003945	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
243265003946	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
243265003947	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265003948	Walker A/P-loop; other site
243265003949	ATP binding site [chemical binding]; other site
243265003950	Q-loop/lid; other site
243265003951	ABC transporter signature motif; other site
243265003952	Walker B; other site
243265003953	D-loop; other site
243265003954	H-loop/switch region; other site
243265003955	quinolinate synthetase; Provisional; Region: PRK09375
243265003956	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
243265003957	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
243265003958	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
243265003959	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
243265003960	catalytic core [active]
243265003961	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
243265003962	CAAX protease self-immunity; Region: Abi; pfam02517
243265003963	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
243265003964	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
243265003965	Walker A/P-loop; other site
243265003966	ATP binding site [chemical binding]; other site
243265003967	Q-loop/lid; other site
243265003968	ABC transporter signature motif; other site
243265003969	Walker B; other site
243265003970	D-loop; other site
243265003971	H-loop/switch region; other site
243265003972	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265003973	Walker A/P-loop; other site
243265003974	ATP binding site [chemical binding]; other site
243265003975	Q-loop/lid; other site
243265003976	ABC transporter signature motif; other site
243265003977	Walker B; other site
243265003978	D-loop; other site
243265003979	H-loop/switch region; other site
243265003980	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
243265003981	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
243265003982	molybdenum-pterin binding domain; Region: Mop; TIGR00638
243265003983	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
243265003984	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
243265003985	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
243265003986	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
243265003987	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265003988	dimer interface [polypeptide binding]; other site
243265003989	conserved gate region; other site
243265003990	putative PBP binding loops; other site
243265003991	ABC-ATPase subunit interface; other site
243265003992	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
243265003993	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265003994	Walker A/P-loop; other site
243265003995	ATP binding site [chemical binding]; other site
243265003996	Q-loop/lid; other site
243265003997	ABC transporter signature motif; other site
243265003998	Walker B; other site
243265003999	D-loop; other site
243265004000	H-loop/switch region; other site
243265004001	TOBE domain; Region: TOBE; cl01440
243265004002	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
243265004003	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265004004	active site
243265004005	motif I; other site
243265004006	motif II; other site
243265004007	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265004008	6-phosphogluconolactonase; Provisional; Region: PRK11028
243265004009	Truncated transposase, IS605 family
243265004010	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
243265004011	RES domain; Region: RES; smart00953
243265004012	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
243265004013	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265004014	inhibitor-cofactor binding pocket; inhibition site
243265004015	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265004016	catalytic residue [active]
243265004017	biotin synthase; Provisional; Region: PRK15108
243265004018	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265004019	FeS/SAM binding site; other site
243265004020	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
243265004021	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
243265004022	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
243265004023	substrate-cofactor binding pocket; other site
243265004024	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265004025	catalytic residue [active]
243265004026	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
243265004027	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265004028	S-adenosylmethionine binding site [chemical binding]; other site
243265004029	AAA domain; Region: AAA_26; pfam13500
243265004030	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
243265004031	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
243265004032	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265004033	non-specific DNA binding site [nucleotide binding]; other site
243265004034	salt bridge; other site
243265004035	sequence-specific DNA binding site [nucleotide binding]; other site
243265004036	excinuclease ABC subunit B; Provisional; Region: PRK05298
243265004037	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265004038	ATP binding site [chemical binding]; other site
243265004039	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265004040	nucleotide binding region [chemical binding]; other site
243265004041	ATP-binding site [chemical binding]; other site
243265004042	Ultra-violet resistance protein B; Region: UvrB; pfam12344
243265004043	UvrB/uvrC motif; Region: UVR; pfam02151
243265004044	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
243265004045	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265004046	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265004047	This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990
243265004048	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
243265004049	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
243265004050	PAAR motif; Region: PAAR_motif; pfam05488
243265004051	Homeodomain-like domain; Region: HTH_23; pfam13384
243265004052	Winged helix-turn helix; Region: HTH_29; pfam13551
243265004053	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265004054	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265004055	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
243265004056	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
243265004057	phosphate binding site [ion binding]; other site
243265004058	putative substrate binding pocket [chemical binding]; other site
243265004059	dimer interface [polypeptide binding]; other site
243265004060	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
243265004061	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265004062	FeS/SAM binding site; other site
243265004063	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
243265004064	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
243265004065	trimer interface [polypeptide binding]; other site
243265004066	dimer interface [polypeptide binding]; other site
243265004067	putative active site [active]
243265004068	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
243265004069	MoaE interaction surface [polypeptide binding]; other site
243265004070	MoeB interaction surface [polypeptide binding]; other site
243265004071	thiocarboxylated glycine; other site
243265004072	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
243265004073	MoaE homodimer interface [polypeptide binding]; other site
243265004074	MoaD interaction [polypeptide binding]; other site
243265004075	active site residues [active]
243265004076	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
243265004077	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
243265004078	hypothetical protein; Provisional; Region: PRK07505
243265004079	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
243265004080	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265004081	catalytic residue [active]
243265004082	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
243265004083	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265004084	putative substrate translocation pore; other site
243265004085	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
243265004086	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
243265004087	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
243265004088	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
243265004089	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
243265004090	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
243265004091	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
243265004092	Walker A/P-loop; other site
243265004093	ATP binding site [chemical binding]; other site
243265004094	Q-loop/lid; other site
243265004095	ABC transporter signature motif; other site
243265004096	Walker B; other site
243265004097	D-loop; other site
243265004098	H-loop/switch region; other site
243265004099	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
243265004100	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
243265004101	Walker A/P-loop; other site
243265004102	ATP binding site [chemical binding]; other site
243265004103	Q-loop/lid; other site
243265004104	ABC transporter signature motif; other site
243265004105	Walker B; other site
243265004106	D-loop; other site
243265004107	H-loop/switch region; other site
243265004108	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
243265004109	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265004110	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265004111	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
243265004112	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
243265004113	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
243265004114	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
243265004115	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
243265004116	ATP binding site [chemical binding]; other site
243265004117	Mg++ binding site [ion binding]; other site
243265004118	motif III; other site
243265004119	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265004120	nucleotide binding region [chemical binding]; other site
243265004121	ATP-binding site [chemical binding]; other site
243265004122	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
243265004123	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
243265004124	FMN binding site [chemical binding]; other site
243265004125	active site
243265004126	catalytic residues [active]
243265004127	substrate binding site [chemical binding]; other site
243265004128	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
243265004129	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265004130	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265004131	putative substrate translocation pore; other site
243265004132	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
243265004133	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
243265004134	ATP binding site [chemical binding]; other site
243265004135	substrate interface [chemical binding]; other site
243265004136	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
243265004137	active site flap/lid [active]
243265004138	nucleophilic elbow; other site
243265004139	catalytic triad [active]
243265004140	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
243265004141	active site flap/lid [active]
243265004142	nucleophilic elbow; other site
243265004143	catalytic triad [active]
243265004144	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
243265004145	active site flap/lid [active]
243265004146	nucleophilic elbow; other site
243265004147	catalytic triad [active]
243265004148	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
243265004149	active site flap/lid [active]
243265004150	nucleophilic elbow; other site
243265004151	catalytic triad [active]
243265004152	Truncated gene. Similar to C-terminal region of transposase
243265004153	Truncated gene. Similar to N-terminal region of transposase
243265004154	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
243265004155	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
243265004156	active site residue [active]
243265004157	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
243265004158	active site residue [active]
243265004159	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
243265004160	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
243265004161	DEAD_2; Region: DEAD_2; pfam06733
243265004162	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
243265004163	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265004164	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265004165	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
243265004166	putative effector binding pocket; other site
243265004167	dimerization interface [polypeptide binding]; other site
243265004168	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
243265004169	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
243265004170	FMN binding site [chemical binding]; other site
243265004171	active site
243265004172	substrate binding site [chemical binding]; other site
243265004173	catalytic residue [active]
243265004174	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
243265004175	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
243265004176	active site
243265004177	catalytic tetrad [active]
243265004178	Truncated gene. Some similarities with transposase
243265004179	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
243265004180	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
243265004181	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
243265004182	inhibitor site; inhibition site
243265004183	active site
243265004184	dimer interface [polypeptide binding]; other site
243265004185	catalytic residue [active]
243265004186	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
243265004187	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
243265004188	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
243265004189	TAP-like protein; Region: Abhydrolase_4; pfam08386
243265004190	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
243265004191	PhnA protein; Region: PhnA; pfam03831
243265004192	Truncated gene. Some high similarities with DNA-binding protein, starvation-inducible Dsp protein of Escherichia coli
243265004193	threonine and homoserine efflux system; Provisional; Region: PRK10532
243265004194	EamA-like transporter family; Region: EamA; pfam00892
243265004195	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
243265004196	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
243265004197	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265004198	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265004199	ABC transporter; Region: ABC_tran_2; pfam12848
243265004200	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265004201	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
243265004202	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
243265004203	ATP binding site [chemical binding]; other site
243265004204	substrate interface [chemical binding]; other site
243265004205	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
243265004206	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
243265004207	dimer interface [polypeptide binding]; other site
243265004208	putative functional site; other site
243265004209	putative MPT binding site; other site
243265004210	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
243265004211	classical (c) SDRs; Region: SDR_c; cd05233
243265004212	NAD(P) binding site [chemical binding]; other site
243265004213	active site
243265004214	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265004215	putative substrate translocation pore; other site
243265004216	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
243265004217	GTP cyclohydrolase I; Provisional; Region: PLN03044
243265004218	active site
243265004219	hypothetical protein; Provisional; Region: PRK10835
243265004220	Predicted membrane protein [Function unknown]; Region: COG2311
243265004221	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
243265004222	putative active site [active]
243265004223	malate dehydrogenase; Provisional; Region: PRK13529
243265004224	Malic enzyme, N-terminal domain; Region: malic; pfam00390
243265004225	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
243265004226	NAD(P) binding site [chemical binding]; other site
243265004227	cytidine deaminase; Provisional; Region: PRK09027
243265004228	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
243265004229	active site
243265004230	catalytic motif [active]
243265004231	Zn binding site [ion binding]; other site
243265004232	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
243265004233	active site
243265004234	catalytic motif [active]
243265004235	Zn binding site [ion binding]; other site
243265004236	hypothetical protein; Provisional; Region: PRK10711
243265004237	hypothetical protein; Provisional; Region: PRK01821
243265004238	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
243265004239	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265004240	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
243265004241	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
243265004242	active site
243265004243	HIGH motif; other site
243265004244	KMSKS motif; other site
243265004245	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
243265004246	tRNA binding surface [nucleotide binding]; other site
243265004247	anticodon binding site; other site
243265004248	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
243265004249	dimer interface [polypeptide binding]; other site
243265004250	putative tRNA-binding site [nucleotide binding]; other site
243265004251	antiporter inner membrane protein; Provisional; Region: PRK11670
243265004252	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
243265004253	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
243265004254	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
243265004255	ATP-binding site [chemical binding]; other site
243265004256	Sugar specificity; other site
243265004257	Pyrimidine base specificity; other site
243265004258	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
243265004259	trimer interface [polypeptide binding]; other site
243265004260	active site
243265004261	putative assembly protein; Provisional; Region: PRK10833
243265004262	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
243265004263	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
243265004264	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
243265004265	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
243265004266	Transporter associated domain; Region: CorC_HlyC; smart01091
243265004267	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
243265004268	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
243265004269	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
243265004270	Protein of unkown function (DUF1881); Region: DUF1881; pfam08964
243265004271	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
243265004272	putative deacylase active site [active]
243265004273	putative alcohol dehydrogenase; Provisional; Region: PRK09860
243265004274	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
243265004275	dimer interface [polypeptide binding]; other site
243265004276	active site
243265004277	metal binding site [ion binding]; metal-binding site
243265004278	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
243265004279	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
243265004280	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
243265004281	metal binding site [ion binding]; metal-binding site
243265004282	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
243265004283	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
243265004284	substrate binding site [chemical binding]; other site
243265004285	glutamase interaction surface [polypeptide binding]; other site
243265004286	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
243265004287	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
243265004288	catalytic residues [active]
243265004289	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
243265004290	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
243265004291	putative active site [active]
243265004292	oxyanion strand; other site
243265004293	catalytic triad [active]
243265004294	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
243265004295	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265004296	active site
243265004297	motif I; other site
243265004298	motif II; other site
243265004299	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
243265004300	putative active site pocket [active]
243265004301	4-fold oligomerization interface [polypeptide binding]; other site
243265004302	metal binding residues [ion binding]; metal-binding site
243265004303	3-fold/trimer interface [polypeptide binding]; other site
243265004304	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
243265004305	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
243265004306	NAD binding site [chemical binding]; other site
243265004307	dimerization interface [polypeptide binding]; other site
243265004308	product binding site; other site
243265004309	substrate binding site [chemical binding]; other site
243265004310	zinc binding site [ion binding]; other site
243265004311	catalytic residues [active]
243265004312	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
243265004313	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265004314	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265004315	homodimer interface [polypeptide binding]; other site
243265004316	catalytic residue [active]
243265004317	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
243265004318	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
243265004319	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
243265004320	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
243265004321	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
243265004322	putative NAD(P) binding site [chemical binding]; other site
243265004323	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
243265004324	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
243265004325	putative C-terminal domain interface [polypeptide binding]; other site
243265004326	putative GSH binding site (G-site) [chemical binding]; other site
243265004327	putative dimer interface [polypeptide binding]; other site
243265004328	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
243265004329	putative N-terminal domain interface [polypeptide binding]; other site
243265004330	putative dimer interface [polypeptide binding]; other site
243265004331	putative substrate binding pocket (H-site) [chemical binding]; other site
243265004332	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
243265004333	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
243265004334	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
243265004335	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
243265004336	serine transporter; Region: stp; TIGR00814
243265004337	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
243265004338	active site
243265004339	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
243265004340	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
243265004341	GSH binding site [chemical binding]; other site
243265004342	catalytic residues [active]
243265004343	hypothetical protein; Provisional; Region: PRK10591
243265004344	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
243265004345	23S rRNA methyluridine methyltransferase; Reviewed; Region: rumB; PRK03522
243265004346	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265004347	S-adenosylmethionine binding site [chemical binding]; other site
243265004348	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265004349	dimer interface [polypeptide binding]; other site
243265004350	conserved gate region; other site
243265004351	putative PBP binding loops; other site
243265004352	ABC-ATPase subunit interface; other site
243265004353	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
243265004354	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265004355	dimer interface [polypeptide binding]; other site
243265004356	conserved gate region; other site
243265004357	putative PBP binding loops; other site
243265004358	ABC-ATPase subunit interface; other site
243265004359	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
243265004360	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265004361	substrate binding pocket [chemical binding]; other site
243265004362	membrane-bound complex binding site; other site
243265004363	hinge residues; other site
243265004364	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
243265004365	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265004366	Walker A/P-loop; other site
243265004367	ATP binding site [chemical binding]; other site
243265004368	Q-loop/lid; other site
243265004369	ABC transporter signature motif; other site
243265004370	Walker B; other site
243265004371	D-loop; other site
243265004372	H-loop/switch region; other site
243265004373	Predicted membrane protein [Function unknown]; Region: COG2431
243265004374	macrolide transporter subunit MacA; Provisional; Region: PRK11578
243265004375	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265004376	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265004377	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
243265004378	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
243265004379	Walker A/P-loop; other site
243265004380	ATP binding site [chemical binding]; other site
243265004381	Q-loop/lid; other site
243265004382	ABC transporter signature motif; other site
243265004383	Walker B; other site
243265004384	D-loop; other site
243265004385	H-loop/switch region; other site
243265004386	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
243265004387	FtsX-like permease family; Region: FtsX; pfam02687
243265004388	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
243265004389	DNA-binding site [nucleotide binding]; DNA binding site
243265004390	RNA-binding motif; other site
243265004391	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
243265004392	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
243265004393	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265004394	Walker A motif; other site
243265004395	ATP binding site [chemical binding]; other site
243265004396	Walker B motif; other site
243265004397	arginine finger; other site
243265004398	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265004399	Walker A motif; other site
243265004400	ATP binding site [chemical binding]; other site
243265004401	Walker B motif; other site
243265004402	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
243265004403	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
243265004404	rRNA binding site [nucleotide binding]; other site
243265004405	predicted 30S ribosome binding site; other site
243265004406	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
243265004407	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
243265004408	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265004409	Walker A/P-loop; other site
243265004410	ATP binding site [chemical binding]; other site
243265004411	Q-loop/lid; other site
243265004412	ABC transporter signature motif; other site
243265004413	Walker B; other site
243265004414	D-loop; other site
243265004415	H-loop/switch region; other site
243265004416	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
243265004417	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265004418	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265004419	Walker A/P-loop; other site
243265004420	ATP binding site [chemical binding]; other site
243265004421	Q-loop/lid; other site
243265004422	ABC transporter signature motif; other site
243265004423	Walker B; other site
243265004424	D-loop; other site
243265004425	H-loop/switch region; other site
243265004426	thioredoxin reductase; Provisional; Region: PRK10262
243265004427	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265004428	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
243265004429	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
243265004430	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
243265004431	putative DNA binding site [nucleotide binding]; other site
243265004432	putative Zn2+ binding site [ion binding]; other site
243265004433	AsnC family; Region: AsnC_trans_reg; pfam01037
243265004434	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
243265004435	DNA translocase FtsK; Provisional; Region: PRK10263
243265004436	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
243265004437	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
243265004438	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
243265004439	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
243265004440	recombination factor protein RarA; Reviewed; Region: PRK13342
243265004441	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265004442	Walker A motif; other site
243265004443	ATP binding site [chemical binding]; other site
243265004444	Walker B motif; other site
243265004445	arginine finger; other site
243265004446	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
243265004447	seryl-tRNA synthetase; Provisional; Region: PRK05431
243265004448	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
243265004449	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
243265004450	dimer interface [polypeptide binding]; other site
243265004451	active site
243265004452	motif 1; other site
243265004453	motif 2; other site
243265004454	motif 3; other site
243265004455	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
243265004456	Transposase [DNA replication, recombination, and repair]; Region: COG5421
243265004457	Truncated gene. Similar to C-terminal region of Unknown protein
243265004458	Truncated gene. Similar to N-terminal region of Unknown protein
243265004459	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
243265004460	Helix-turn-helix domain; Region: HTH_38; pfam13936
243265004461	Homeodomain-like domain; Region: HTH_32; pfam13565
243265004462	Integrase core domain; Region: rve; pfam00665
243265004463	Protein of unknown function (DUF796); Region: DUF796; cl01226
243265004464	putative transposase; Provisional; Region: PRK09857
243265004465	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265004466	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
243265004467	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265004468	FeS/SAM binding site; other site
243265004469	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
243265004470	Pyruvate formate lyase 1; Region: PFL1; cd01678
243265004471	coenzyme A binding site [chemical binding]; other site
243265004472	active site
243265004473	catalytic residues [active]
243265004474	glycine loop; other site
243265004475	formate transporter; Provisional; Region: PRK10805
243265004476	uncharacterized domain; Region: TIGR00702
243265004477	YcaO-like family; Region: YcaO; pfam02624
243265004478	L-asparaginase II; Provisional; Region: ansB; PRK11096
243265004479	homodimer interface [polypeptide binding]; other site
243265004480	active site
243265004481	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
243265004482	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
243265004483	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265004484	Coenzyme A binding pocket [chemical binding]; other site
243265004485	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
243265004486	homodimer interface [polypeptide binding]; other site
243265004487	substrate-cofactor binding pocket; other site
243265004488	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265004489	catalytic residue [active]
243265004490	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
243265004491	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
243265004492	hinge; other site
243265004493	active site
243265004494	cytidylate kinase; Provisional; Region: cmk; PRK00023
243265004495	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
243265004496	CMP-binding site; other site
243265004497	The sites determining sugar specificity; other site
243265004498	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
243265004499	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
243265004500	RNA binding site [nucleotide binding]; other site
243265004501	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
243265004502	RNA binding site [nucleotide binding]; other site
243265004503	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
243265004504	RNA binding site [nucleotide binding]; other site
243265004505	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
243265004506	RNA binding site [nucleotide binding]; other site
243265004507	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
243265004508	RNA binding site [nucleotide binding]; other site
243265004509	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
243265004510	RNA binding site [nucleotide binding]; other site
243265004511	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
243265004512	IHF dimer interface [polypeptide binding]; other site
243265004513	IHF - DNA interface [nucleotide binding]; other site
243265004514	Truncated gene. Some similarities with Unknown protein
243265004515	LysE type translocator; Region: LysE; cl00565
243265004516	ComEC family competence protein; Provisional; Region: PRK11539
243265004517	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
243265004518	Competence protein; Region: Competence; pfam03772
243265004519	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
243265004520	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
243265004521	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265004522	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
243265004523	Walker A/P-loop; other site
243265004524	ATP binding site [chemical binding]; other site
243265004525	Q-loop/lid; other site
243265004526	ABC transporter signature motif; other site
243265004527	Walker B; other site
243265004528	D-loop; other site
243265004529	H-loop/switch region; other site
243265004530	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
243265004531	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
243265004532	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
243265004533	DNA-binding site [nucleotide binding]; DNA binding site
243265004534	RNA-binding motif; other site
243265004535	Trm112p-like protein; Region: Trm112p; cl01066
243265004536	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
243265004537	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
243265004538	Ligand binding site; other site
243265004539	oligomer interface; other site
243265004540	Uncharacterized conserved protein [Function unknown]; Region: COG1434
243265004541	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
243265004542	putative active site [active]
243265004543	Methyltransferase domain; Region: Methyltransf_31; pfam13847
243265004544	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265004545	S-adenosylmethionine binding site [chemical binding]; other site
243265004546	condesin subunit F; Provisional; Region: PRK05260
243265004547	condesin subunit E; Provisional; Region: PRK05256
243265004548	cell division protein MukB; Provisional; Region: mukB; PRK04863
243265004549	P-loop containing region of AAA domain; Region: AAA_29; cl17516
243265004550	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
243265004551	RES domain; Region: RES; pfam08808
243265004552	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
243265004553	putative transposase; Provisional; Region: PRK09857
243265004554	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265004555	Truncated gene. Some similarities with transposase
243265004556	Truncated gene, similar to photopexin A and B
243265004557	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265004558	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265004559	Truncated gene, similar to photopexin A and B
243265004560	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
243265004561	Phage Tail Collar Domain; Region: Collar; pfam07484
243265004562	Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: LeuS; COG0495
243265004563	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
243265004564	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
243265004565	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265004566	Walker A motif; other site
243265004567	ATP binding site [chemical binding]; other site
243265004568	Walker B motif; other site
243265004569	Phage Tail Collar Domain; Region: Collar; pfam07484
243265004570	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
243265004571	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265004572	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265004573	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265004574	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
243265004575	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004576	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004577	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
243265004578	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004579	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; cl17313
243265004580	putative transposase; Provisional; Region: PRK09857
243265004581	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265004582	Truncated gene. Some similarities with Unknown protein
243265004583	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK14869
243265004584	Truncated gene. Highly similar to Cterm of Unknown protein of Photorhabdus
243265004585	Truncated gene. Highly similar to Nterm of Unknown protein of Photorhabdus
243265004586	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
243265004587	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265004588	Walker A motif; other site
243265004589	ATP binding site [chemical binding]; other site
243265004590	Walker B motif; other site
243265004591	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
243265004592	Phage Tail Collar Domain; Region: Collar; pfam07484
243265004593	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
243265004594	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
243265004595	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265004596	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265004597	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
243265004598	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004599	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004600	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004601	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; cl17313
243265004602	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
243265004603	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
243265004604	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265004605	Walker A motif; other site
243265004606	ATP binding site [chemical binding]; other site
243265004607	Walker B motif; other site
243265004608	arginine finger; other site
243265004609	Homeodomain-like domain; Region: HTH_23; pfam13384
243265004610	Winged helix-turn helix; Region: HTH_29; pfam13551
243265004611	Winged helix-turn helix; Region: HTH_33; pfam13592
243265004612	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265004613	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265004614	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
243265004615	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
243265004616	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265004617	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265004618	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
243265004619	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004620	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004621	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004622	conserved hypothetical phage tail region protein; Region: TIGR02241
243265004623	Truncated gene. Weakly similar to  transposase
243265004624	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265004625	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
243265004626	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
243265004627	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
243265004628	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265004629	Walker A motif; other site
243265004630	ATP binding site [chemical binding]; other site
243265004631	Walker B motif; other site
243265004632	Phage Tail Collar Domain; Region: Collar; pfam07484
243265004633	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
243265004634	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
243265004635	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265004636	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265004637	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
243265004638	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004639	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004640	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265004641	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; cl17313
243265004642	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
243265004643	protein-splicing catalytic site; other site
243265004644	thioester formation/cholesterol transfer; other site
243265004645	PilS N terminal; Region: PilS; pfam08805
243265004646	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
243265004647	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
243265004648	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
243265004649	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
243265004650	type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520
243265004651	Secretin N-terminal domain; Region: Secretin_N_2; pfam07655
243265004652	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
243265004653	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
243265004654	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
243265004655	Type II/IV secretion system protein; Region: T2SE; pfam00437
243265004656	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
243265004657	Walker A motif; other site
243265004658	ATP binding site [chemical binding]; other site
243265004659	Walker B motif; other site
243265004660	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
243265004661	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
243265004662	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
243265004663	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
243265004664	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
243265004665	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
243265004666	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
243265004667	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
243265004668	Truncated gene. Similar to N-terminal part of amidase YcbB precursor of Escherichia coli
243265004669	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
243265004670	Transposase [DNA replication, recombination, and repair]; Region: COG5421
243265004671	Truncated gene. Similar to C-terminal part of amidase YcbB precursor of Escherichia coli
243265004672	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
243265004673	Peptidase M15; Region: Peptidase_M15_3; cl01194
243265004674	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
243265004675	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
243265004676	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265004677	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265004678	homodimer interface [polypeptide binding]; other site
243265004679	catalytic residue [active]
243265004680	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
243265004681	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
243265004682	trimer interface [polypeptide binding]; other site
243265004683	eyelet of channel; other site
243265004684	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
243265004685	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
243265004686	trimer interface [polypeptide binding]; other site
243265004687	eyelet of channel; other site
243265004688	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
243265004689	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
243265004690	putative dimer interface [polypeptide binding]; other site
243265004691	putative anticodon binding site; other site
243265004692	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
243265004693	homodimer interface [polypeptide binding]; other site
243265004694	motif 1; other site
243265004695	motif 2; other site
243265004696	active site
243265004697	motif 3; other site
243265004698	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
243265004699	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
243265004700	active site
243265004701	aminopeptidase N; Provisional; Region: pepN; PRK14015
243265004702	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
243265004703	active site
243265004704	Zn binding site [ion binding]; other site
243265004705	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
243265004706	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
243265004707	quinone interaction residues [chemical binding]; other site
243265004708	active site
243265004709	catalytic residues [active]
243265004710	FMN binding site [chemical binding]; other site
243265004711	substrate binding site [chemical binding]; other site
243265004712	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
243265004713	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
243265004714	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
243265004715	active site
243265004716	TDP-binding site; other site
243265004717	acceptor substrate-binding pocket; other site
243265004718	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265004719	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265004720	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
243265004721	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
243265004722	active site
243265004723	TDP-binding site; other site
243265004724	acceptor substrate-binding pocket; other site
243265004725	homodimer interface [polypeptide binding]; other site
243265004726	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
243265004727	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
243265004728	MOSC domain; Region: MOSC; pfam03473
243265004729	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
243265004730	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
243265004731	catalytic loop [active]
243265004732	iron binding site [ion binding]; other site
243265004733	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
243265004734	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
243265004735	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
243265004736	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265004737	S-adenosylmethionine binding site [chemical binding]; other site
243265004738	ABC transporter ATPase component; Reviewed; Region: PRK11147
243265004739	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265004740	Walker A/P-loop; other site
243265004741	ATP binding site [chemical binding]; other site
243265004742	Q-loop/lid; other site
243265004743	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265004744	ABC transporter signature motif; other site
243265004745	Walker B; other site
243265004746	ABC transporter; Region: ABC_tran_2; pfam12848
243265004747	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265004748	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
243265004749	Paraquat-inducible protein A; Region: PqiA; pfam04403
243265004750	Paraquat-inducible protein A; Region: PqiA; pfam04403
243265004751	paraquat-inducible protein B; Provisional; Region: PRK10807
243265004752	mce related protein; Region: MCE; pfam02470
243265004753	mce related protein; Region: MCE; pfam02470
243265004754	mce related protein; Region: MCE; pfam02470
243265004755	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
243265004756	Protein of unknown function (DUF330); Region: DUF330; pfam03886
243265004757	ribosome modulation factor; Provisional; Region: PRK14563
243265004758	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
243265004759	active site 1 [active]
243265004760	dimer interface [polypeptide binding]; other site
243265004761	active site 2 [active]
243265004762	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
243265004763	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
243265004764	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
243265004765	outer membrane protein A; Reviewed; Region: PRK10808
243265004766	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
243265004767	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
243265004768	ligand binding site [chemical binding]; other site
243265004769	SOS cell division inhibitor; Provisional; Region: PRK10595
243265004770	TfoX N-terminal domain; Region: TfoX_N; pfam04993
243265004771	TfoX C-terminal domain; Region: TfoX_C; pfam04994
243265004772	TIGR01666 family membrane protein; Region: YCCS
243265004773	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
243265004774	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
243265004775	DNA helicase IV; Provisional; Region: helD; PRK11054
243265004776	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
243265004777	Part of AAA domain; Region: AAA_19; pfam13245
243265004778	Family description; Region: UvrD_C_2; pfam13538
243265004779	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
243265004780	active site
243265004781	dimer interfaces [polypeptide binding]; other site
243265004782	catalytic residues [active]
243265004783	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
243265004784	heat shock protein HspQ; Provisional; Region: PRK14129
243265004785	Acylphosphatase; Region: Acylphosphatase; cl00551
243265004786	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
243265004787	sulfur relay protein, TusE/DsrC/DsvC family; Region: dsrC_tusE_dsvC; TIGR03342
243265004788	Homeodomain-like domain; Region: HTH_23; pfam13384
243265004789	Winged helix-turn helix; Region: HTH_29; pfam13551
243265004790	Winged helix-turn helix; Region: HTH_33; pfam13592
243265004791	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265004792	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265004793	Truncated gene, similar to C terminal part of Unknown protein
243265004794	CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673
243265004795	CRISPR-associated helicase Cas3, subtype I-F/YPEST; Region: cas3_yersinia; TIGR02562
243265004796	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
243265004797	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cd09735
243265004798	CRISPR/Cas system-associated RAMP superfamily protein Csy2; Region: Csy2_I-F; cd09736
243265004799	CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cd09737
243265004800	CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cd09739
243265004801	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
243265004802	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
243265004803	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
243265004804	DNA interaction; other site
243265004805	Metal-binding active site; metal-binding site
243265004806	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
243265004807	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
243265004808	substrate binding site [chemical binding]; other site
243265004809	ATP binding site [chemical binding]; other site
243265004810	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
243265004811	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
243265004812	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
243265004813	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
243265004814	putative transporter; Provisional; Region: PRK10484
243265004815	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
243265004816	Na binding site [ion binding]; other site
243265004817	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
243265004818	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
243265004819	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
243265004820	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
243265004821	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
243265004822	PYR/PP interface [polypeptide binding]; other site
243265004823	dimer interface [polypeptide binding]; other site
243265004824	TPP binding site [chemical binding]; other site
243265004825	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
243265004826	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
243265004827	TPP-binding site; other site
243265004828	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
243265004829	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
243265004830	tetrameric interface [polypeptide binding]; other site
243265004831	NAD binding site [chemical binding]; other site
243265004832	catalytic residues [active]
243265004833	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
243265004834	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
243265004835	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
243265004836	putative active site [active]
243265004837	HrcA protein C terminal domain; Region: HrcA; pfam01628
243265004838	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
243265004839	dimer interface [polypeptide binding]; other site
243265004840	putative tRNA-binding site [nucleotide binding]; other site
243265004841	Cupin domain; Region: Cupin_2; cl17218
243265004842	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
243265004843	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265004844	Plasmid maintenance system killer protein [General function prediction only]; Region: HigB; COG3549
243265004845	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
243265004846	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265004847	sequence-specific DNA binding site [nucleotide binding]; other site
243265004848	salt bridge; other site
243265004849	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
243265004850	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265004851	putative substrate translocation pore; other site
243265004852	POT family; Region: PTR2; cl17359
243265004853	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
243265004854	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
243265004855	putative acyl-acceptor binding pocket; other site
243265004856	DinI-like family; Region: DinI; cl11630
243265004857	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
243265004858	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
243265004859	active site residue [active]
243265004860	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265004861	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265004862	DNA binding residues [nucleotide binding]
243265004863	dimerization interface [polypeptide binding]; other site
243265004864	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
243265004865	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
243265004866	active site
243265004867	substrate binding pocket [chemical binding]; other site
243265004868	dimer interface [polypeptide binding]; other site
243265004869	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265004870	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265004871	bacteriocin maturation radical SAM protein 1; Region: rSAM_ocin_1; TIGR03975
243265004872	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
243265004873	Helix-turn-helix domain; Region: HTH_38; pfam13936
243265004874	Homeodomain-like domain; Region: HTH_32; pfam13565
243265004875	Integrase core domain; Region: rve; pfam00665
243265004876	Truncated transposase, IS4 familly (ISPlu9-p)
243265004877	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
243265004878	MobA/MobL family; Region: MobA_MobL; pfam03389
243265004879	Conjugal transfer protein TraD; Region: TraD; pfam06412
243265004880	Domain of unknown function (DUF4297); Region: DUF4297; pfam14130
243265004881	Truncated gene. Similar to C-terminal region of pathogenicity island integrase
243265004882	Truncated gene. Similar to N-terminal region of integrase
243265004883	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
243265004884	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
243265004885	DNA-binding site [nucleotide binding]; DNA binding site
243265004886	RNA-binding motif; other site
243265004887	magnesium transport protein MgtC; Provisional; Region: PRK15385
243265004888	MgtC family; Region: MgtC; pfam02308
243265004889	Truncated gene. Some similarities with Mg(2+) transport ATPase B
243265004890	Truncated gene. Some similarities with Mg(2+) transport ATPase B
243265004891	transcriptional activator FlhD; Provisional; Region: PRK02909
243265004892	transcriptional activator FlhC; Provisional; Region: PRK12722
243265004893	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
243265004894	flagellar motor protein MotA; Validated; Region: PRK09110
243265004895	flagellar motor protein MotB; Validated; Region: motB; PRK09041
243265004896	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
243265004897	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
243265004898	ligand binding site [chemical binding]; other site
243265004899	chemotaxis protein CheA; Provisional; Region: PRK10547
243265004900	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
243265004901	putative binding surface; other site
243265004902	active site
243265004903	CheY binding; Region: CheY-binding; pfam09078
243265004904	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
243265004905	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265004906	ATP binding site [chemical binding]; other site
243265004907	Mg2+ binding site [ion binding]; other site
243265004908	G-X-G motif; other site
243265004909	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
243265004910	purine-binding chemotaxis protein; Provisional; Region: PRK10612
243265004911	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
243265004912	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
243265004913	dimer interface [polypeptide binding]; other site
243265004914	ligand binding site [chemical binding]; other site
243265004915	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
243265004916	dimerization interface [polypeptide binding]; other site
243265004917	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
243265004918	dimer interface [polypeptide binding]; other site
243265004919	putative CheW interface [polypeptide binding]; other site
243265004920	methyl-accepting protein IV; Provisional; Region: PRK09793
243265004921	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
243265004922	dimer interface [polypeptide binding]; other site
243265004923	ligand binding site [chemical binding]; other site
243265004924	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
243265004925	dimerization interface [polypeptide binding]; other site
243265004926	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
243265004927	dimer interface [polypeptide binding]; other site
243265004928	putative CheW interface [polypeptide binding]; other site
243265004929	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
243265004930	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
243265004931	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265004932	S-adenosylmethionine binding site [chemical binding]; other site
243265004933	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
243265004934	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265004935	active site
243265004936	phosphorylation site [posttranslational modification]
243265004937	intermolecular recognition site; other site
243265004938	dimerization interface [polypeptide binding]; other site
243265004939	CheB methylesterase; Region: CheB_methylest; pfam01339
243265004940	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
243265004941	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265004942	active site
243265004943	phosphorylation site [posttranslational modification]
243265004944	intermolecular recognition site; other site
243265004945	dimerization interface [polypeptide binding]; other site
243265004946	chemotaxis regulator CheZ; Provisional; Region: PRK11166
243265004947	Transposase IS200 like; Region: Y1_Tnp; pfam01797
243265004948	Truncated transposase, IS110 family
243265004949	Truncated gene. Similar to transposase, IS110 family
243265004950	Truncated gene. Similar to transposase, IS110 family
243265004951	Members of the ICL/PEPM_KPHMT enzyme superfamily catalyze the formation and cleavage of either P-C or C-C bonds. Typical members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate...; Region: ICL_KPHMT; cl00435
243265004952	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
243265004953	active site
243265004954	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
243265004955	tetramer interface [polypeptide binding]; other site
243265004956	Mg2+/Mn2+ binding site [ion binding]; other site
243265004957	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
243265004958	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
243265004959	active site
243265004960	non-prolyl cis peptide bond; other site
243265004961	Truncated gene, similar to N-terminal of homocitrate synthase
243265004962	Truncated gene, similar to C-terminal of homocitrate synthase
243265004963	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
243265004964	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
243265004965	substrate binding site [chemical binding]; other site
243265004966	ligand binding site [chemical binding]; other site
243265004967	3-isopropylmalate dehydratase, small subunit; Region: LEUD_arch; TIGR02087
243265004968	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
243265004969	substrate binding site [chemical binding]; other site
243265004970	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265004971	S-adenosylmethionine binding site [chemical binding]; other site
243265004972	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265004973	Coenzyme A binding pocket [chemical binding]; other site
243265004974	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265004975	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265004976	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265004977	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265004978	putative substrate translocation pore; other site
243265004979	SnoaL-like domain; Region: SnoaL_2; pfam12680
243265004980	Condensation domain; Region: Condensation; pfam00668
243265004981	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265004982	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265004983	acyl-activating enzyme (AAE) consensus motif; other site
243265004984	AMP binding site [chemical binding]; other site
243265004985	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265004986	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265004987	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265004988	putative substrate translocation pore; other site
243265004989	Condensation domain; Region: Condensation; pfam00668
243265004990	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265004991	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265004992	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265004993	acyl-activating enzyme (AAE) consensus motif; other site
243265004994	AMP binding site [chemical binding]; other site
243265004995	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265004996	Condensation domain; Region: Condensation; pfam00668
243265004997	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265004998	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265004999	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265005000	acyl-activating enzyme (AAE) consensus motif; other site
243265005001	AMP binding site [chemical binding]; other site
243265005002	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265005003	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
243265005004	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
243265005005	active site
243265005006	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
243265005007	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
243265005008	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
243265005009	putative NADP binding site [chemical binding]; other site
243265005010	KR domain; Region: KR; pfam08659
243265005011	active site
243265005012	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265005013	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
243265005014	Biofilm formation and stress response factor; Region: BsmA; pfam10014
243265005015	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
243265005016	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
243265005017	tetramer interface [polypeptide binding]; other site
243265005018	TPP-binding site [chemical binding]; other site
243265005019	heterodimer interface [polypeptide binding]; other site
243265005020	phosphorylation loop region [posttranslational modification]
243265005021	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
243265005022	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
243265005023	PYR/PP interface [polypeptide binding]; other site
243265005024	dimer interface [polypeptide binding]; other site
243265005025	TPP binding site [chemical binding]; other site
243265005026	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
243265005027	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
243265005028	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
243265005029	E3 interaction surface; other site
243265005030	lipoyl attachment site [posttranslational modification]; other site
243265005031	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
243265005032	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
243265005033	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK06333
243265005034	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
243265005035	active site
243265005036	Ectoine synthase; Region: Ectoine_synth; cl17598
243265005037	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
243265005038	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
243265005039	Some high similarities with Unknown protein of Photorhabdus and with killer protein of pyocin S3
243265005040	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
243265005041	PAAR motif; Region: PAAR_motif; pfam05488
243265005042	S-type Pyocin; Region: Pyocin_S; pfam06958
243265005043	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
243265005044	active site
243265005045	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK12468
243265005046	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
243265005047	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
243265005048	FHIPEP family; Region: FHIPEP; pfam00771
243265005049	Homeodomain-like domain; Region: HTH_23; pfam13384
243265005050	Winged helix-turn helix; Region: HTH_29; pfam13551
243265005051	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265005052	FG-GAP repeat; Region: FG-GAP_2; pfam14312
243265005053	FG-GAP repeat; Region: FG-GAP_2; pfam14312
243265005054	Glucuronate isomerase; Region: UxaC; cl00829
243265005055	FlgN protein; Region: FlgN; cl09176
243265005056	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
243265005057	SAF-like; Region: SAF_2; pfam13144
243265005058	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
243265005059	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
243265005060	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
243265005061	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
243265005062	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
243265005063	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
243265005064	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
243265005065	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
243265005066	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
243265005067	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
243265005068	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
243265005069	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
243265005070	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
243265005071	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
243265005072	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
243265005073	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
243265005074	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
243265005075	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
243265005076	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
243265005077	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
243265005078	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
243265005079	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
243265005080	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
243265005081	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
243265005082	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
243265005083	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
243265005084	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
243265005085	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
243265005086	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
243265005087	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
243265005088	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
243265005089	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
243265005090	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265005091	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265005092	Domain of unknown function (DUF4123); Region: DUF4123; pfam13503
243265005093	Uncharacterized conserved protein [Function unknown]; Region: COG4104
243265005094	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265005095	salt bridge; other site
243265005096	non-specific DNA binding site [nucleotide binding]; other site
243265005097	sequence-specific DNA binding site [nucleotide binding]; other site
243265005098	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
243265005099	Predicted transcriptional regulator [Transcription]; Region: COG3905
243265005100	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
243265005101	Protein of unknown function (DUF1156); Region: DUF1156; pfam06634
243265005102	DNA methylase; Region: N6_N4_Mtase; cl17433
243265005103	Methyltransferase domain; Region: Methyltransf_26; pfam13659
243265005104	DNA methylase; Region: N6_N4_Mtase; cl17433
243265005105	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
243265005106	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
243265005107	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
243265005108	Flagellar biosynthesis protein, FliO; Region: FliO; cl01247
243265005109	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
243265005110	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
243265005111	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
243265005112	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
243265005113	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
243265005114	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
243265005115	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
243265005116	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
243265005117	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
243265005118	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
243265005119	Walker A motif/ATP binding site; other site
243265005120	Walker B motif; other site
243265005121	flagellar assembly protein H; Validated; Region: fliH; PRK05687
243265005122	Flagellar assembly protein FliH; Region: FliH; pfam02108
243265005123	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
243265005124	FliG C-terminal domain; Region: FliG_C; pfam01706
243265005125	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
243265005126	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
243265005127	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
243265005128	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
243265005129	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
243265005130	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
243265005131	flagellar protein FliS; Validated; Region: fliS; PRK05685
243265005132	flagellar capping protein; Reviewed; Region: fliD; PRK08032
243265005133	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
243265005134	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
243265005135	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
243265005136	flagellin; Validated; Region: PRK06819
243265005137	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
243265005138	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
243265005139	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
243265005140	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265005141	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
243265005142	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265005143	DNA binding residues [nucleotide binding]
243265005144	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
243265005145	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
243265005146	Predicted transcriptional regulator [Transcription]; Region: COG3905
243265005147	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
243265005148	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
243265005149	Glutamate binding site [chemical binding]; other site
243265005150	NAD binding site [chemical binding]; other site
243265005151	catalytic residues [active]
243265005152	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
243265005153	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
243265005154	Na binding site [ion binding]; other site
243265005155	D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_1; cd07809
243265005156	N- and C-terminal domain interface [polypeptide binding]; other site
243265005157	D-xylulose kinase; Region: XylB; TIGR01312
243265005158	active site
243265005159	MgATP binding site [chemical binding]; other site
243265005160	catalytic site [active]
243265005161	metal binding site [ion binding]; metal-binding site
243265005162	xylulose binding site [chemical binding]; other site
243265005163	putative homodimer interface [polypeptide binding]; other site
243265005164	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
243265005165	L-idonate 5-dehydrogenase; Region: PLN02702
243265005166	inhibitor binding site; inhibition site
243265005167	catalytic Zn binding site [ion binding]; other site
243265005168	structural Zn binding site [ion binding]; other site
243265005169	NADP binding site [chemical binding]; other site
243265005170	tetramer interface [polypeptide binding]; other site
243265005171	Weakly similar to transposase
243265005172	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
243265005173	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
243265005174	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
243265005175	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
243265005176	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
243265005177	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265005178	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
243265005179	dimerization interface [polypeptide binding]; other site
243265005180	substrate binding pocket [chemical binding]; other site
243265005181	permease DsdX; Provisional; Region: PRK09921
243265005182	gluconate transporter; Region: gntP; TIGR00791
243265005183	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
243265005184	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
243265005185	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265005186	catalytic residue [active]
243265005187	Putative catalytic domain, repeat 1, of Yersinia pestis murine toxin-like proteins; Region: PLDc_Ymt_1; cd09150
243265005188	putative active site [active]
243265005189	catalytic site [active]
243265005190	Putative catalytic domain, repeat 2, of Yersinia pestis murine toxin-like proteins; Region: PLDc_Ymt_2; cd09151
243265005191	PLD-like domain; Region: PLDc_2; pfam13091
243265005192	putative active site [active]
243265005193	catalytic site [active]
243265005194	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
243265005195	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
243265005196	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
243265005197	FMN binding site [chemical binding]; other site
243265005198	active site
243265005199	substrate binding site [chemical binding]; other site
243265005200	catalytic residue [active]
243265005201	Ketosteroid isomerase-related protein [General function prediction only]; Region: COG3631
243265005202	Rrf2 family protein; Region: rrf2_super; TIGR00738
243265005203	Transcriptional regulator; Region: Rrf2; pfam02082
243265005204	Transcriptional regulators [Transcription]; Region: PurR; COG1609
243265005205	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
243265005206	DNA binding site [nucleotide binding]
243265005207	domain linker motif; other site
243265005208	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
243265005209	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
243265005210	active site
243265005211	phosphorylation site [posttranslational modification]
243265005212	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
243265005213	active site
243265005214	P-loop; other site
243265005215	phosphorylation site [posttranslational modification]
243265005216	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
243265005217	PAS fold; Region: PAS_4; pfam08448
243265005218	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005219	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005220	DNA binding residues [nucleotide binding]
243265005221	dimerization interface [polypeptide binding]; other site
243265005222	Truncated gene. Weakly similar to transcription regulator LuxR family
243265005223	Truncated gene. Weakly similar to transcription regulator LuxR family
243265005224	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
243265005225	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
243265005226	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
243265005227	putative active site [active]
243265005228	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
243265005229	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
243265005230	NAD binding site [chemical binding]; other site
243265005231	sugar binding site [chemical binding]; other site
243265005232	divalent metal binding site [ion binding]; other site
243265005233	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
243265005234	dimer interface [polypeptide binding]; other site
243265005235	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
243265005236	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
243265005237	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
243265005238	active site turn [active]
243265005239	phosphorylation site [posttranslational modification]
243265005240	Some similarities with Unknown protein YhfS of Escherichia coli
243265005241	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
243265005242	active site
243265005243	DNA binding site [nucleotide binding]
243265005244	Int/Topo IB signature motif; other site
243265005245	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
243265005246	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
243265005247	active site
243265005248	phosphorylation site [posttranslational modification]
243265005249	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
243265005250	dimerization domain swap beta strand [polypeptide binding]; other site
243265005251	regulatory protein interface [polypeptide binding]; other site
243265005252	active site
243265005253	regulatory phosphorylation site [posttranslational modification]; other site
243265005254	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
243265005255	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
243265005256	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
243265005257	active site
243265005258	P-loop; other site
243265005259	phosphorylation site [posttranslational modification]
243265005260	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
243265005261	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
243265005262	DNA-binding site [nucleotide binding]; DNA binding site
243265005263	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
243265005264	dimer interface [polypeptide binding]; other site
243265005265	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
243265005266	active site
243265005267	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
243265005268	substrate binding site [chemical binding]; other site
243265005269	catalytic residue [active]
243265005270	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
243265005271	active site
243265005272	substrate binding pocket [chemical binding]; other site
243265005273	homodimer interaction site [polypeptide binding]; other site
243265005274	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
243265005275	Protein of unknown function; Region: YhfT; pfam10797
243265005276	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
243265005277	PAS fold; Region: PAS_4; pfam08448
243265005278	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005279	DNA binding residues [nucleotide binding]
243265005280	dimerization interface [polypeptide binding]; other site
243265005281	PAS fold; Region: PAS_4; pfam08448
243265005282	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005283	DNA binding residues [nucleotide binding]
243265005284	dimerization interface [polypeptide binding]; other site
243265005285	PAS fold; Region: PAS_4; pfam08448
243265005286	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005287	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005288	DNA binding residues [nucleotide binding]
243265005289	dimerization interface [polypeptide binding]; other site
243265005290	PAS fold; Region: PAS_4; pfam08448
243265005291	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005292	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005293	DNA binding residues [nucleotide binding]
243265005294	dimerization interface [polypeptide binding]; other site
243265005295	PAS fold; Region: PAS_4; pfam08448
243265005296	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005297	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005298	DNA binding residues [nucleotide binding]
243265005299	dimerization interface [polypeptide binding]; other site
243265005300	PAS fold; Region: PAS_4; pfam08448
243265005301	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005302	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005303	DNA binding residues [nucleotide binding]
243265005304	dimerization interface [polypeptide binding]; other site
243265005305	PAS fold; Region: PAS_4; pfam08448
243265005306	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005307	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005308	DNA binding residues [nucleotide binding]
243265005309	dimerization interface [polypeptide binding]; other site
243265005310	PAS fold; Region: PAS_4; pfam08448
243265005311	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005312	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005313	DNA binding residues [nucleotide binding]
243265005314	dimerization interface [polypeptide binding]; other site
243265005315	PAS fold; Region: PAS_4; pfam08448
243265005316	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005317	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005318	DNA binding residues [nucleotide binding]
243265005319	dimerization interface [polypeptide binding]; other site
243265005320	PAS fold; Region: PAS_4; pfam08448
243265005321	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005322	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005323	DNA binding residues [nucleotide binding]
243265005324	dimerization interface [polypeptide binding]; other site
243265005325	PAS fold; Region: PAS_4; pfam08448
243265005326	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005327	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005328	DNA binding residues [nucleotide binding]
243265005329	dimerization interface [polypeptide binding]; other site
243265005330	PAS fold; Region: PAS_4; pfam08448
243265005331	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005332	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005333	DNA binding residues [nucleotide binding]
243265005334	dimerization interface [polypeptide binding]; other site
243265005335	PAS fold; Region: PAS_4; pfam08448
243265005336	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005337	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005338	DNA binding residues [nucleotide binding]
243265005339	dimerization interface [polypeptide binding]; other site
243265005340	Truncated gene. Some similarities with probable transcriptional regulator, LuxR family protein of Photorhabdus
243265005341	PAS fold; Region: PAS_4; pfam08448
243265005342	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005343	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005344	DNA binding residues [nucleotide binding]
243265005345	dimerization interface [polypeptide binding]; other site
243265005346	PAS fold; Region: PAS_4; pfam08448
243265005347	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
243265005348	DNA binding residues [nucleotide binding]
243265005349	Truncated gene. Some similarities with killer protein of pyocin S3-like of Photorhabdus luminescens
243265005350	PAS fold; Region: PAS_4; pfam08448
243265005351	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005352	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005353	DNA binding residues [nucleotide binding]
243265005354	dimerization interface [polypeptide binding]; other site
243265005355	PAS fold; Region: PAS_4; pfam08448
243265005356	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265005357	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005358	DNA binding residues [nucleotide binding]
243265005359	dimerization interface [polypeptide binding]; other site
243265005360	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
243265005361	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
243265005362	trimer interface [polypeptide binding]; other site
243265005363	active site
243265005364	substrate binding site [chemical binding]; other site
243265005365	CoA binding site [chemical binding]; other site
243265005366	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265005367	Phage Tail Collar Domain; Region: Collar; pfam07484
243265005368	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265005369	Phage Tail Collar Domain; Region: Collar; pfam07484
243265005370	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265005371	Phage Tail Collar Domain; Region: Collar; pfam07484
243265005372	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
243265005373	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
243265005374	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
243265005375	GIY-YIG motif/motif A; other site
243265005376	active site
243265005377	catalytic site [active]
243265005378	putative DNA binding site [nucleotide binding]; other site
243265005379	metal binding site [ion binding]; metal-binding site
243265005380	UvrB/uvrC motif; Region: UVR; pfam02151
243265005381	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
243265005382	response regulator; Provisional; Region: PRK09483
243265005383	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265005384	active site
243265005385	phosphorylation site [posttranslational modification]
243265005386	intermolecular recognition site; other site
243265005387	dimerization interface [polypeptide binding]; other site
243265005388	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265005389	DNA binding residues [nucleotide binding]
243265005390	dimerization interface [polypeptide binding]; other site
243265005391	Protein of unknown function (DUF2594); Region: DUF2594; pfam10769
243265005392	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
243265005393	Ligand Binding Site [chemical binding]; other site
243265005394	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
243265005395	Ligand Binding Site [chemical binding]; other site
243265005396	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
243265005397	amphipathic channel; other site
243265005398	Asn-Pro-Ala signature motifs; other site
243265005399	Phage Tail Collar Domain; Region: Collar; pfam07484
243265005400	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265005401	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265005402	DNA-specific endonuclease I; Provisional; Region: PRK15137
243265005403	Endonuclease I; Region: Endonuclease_1; pfam04231
243265005404	hypothetical protein; Provisional; Region: PRK10536
243265005405	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
243265005406	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
243265005407	FAD binding pocket [chemical binding]; other site
243265005408	FAD binding motif [chemical binding]; other site
243265005409	phosphate binding motif [ion binding]; other site
243265005410	NAD binding pocket [chemical binding]; other site
243265005411	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
243265005412	Histidine kinase; Region: HisKA_3; pfam07730
243265005413	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265005414	ATP binding site [chemical binding]; other site
243265005415	Mg2+ binding site [ion binding]; other site
243265005416	G-X-G motif; other site
243265005417	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
243265005418	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
243265005419	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
243265005420	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
243265005421	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
243265005422	DNA-binding site [nucleotide binding]; DNA binding site
243265005423	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265005424	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265005425	homodimer interface [polypeptide binding]; other site
243265005426	catalytic residue [active]
243265005427	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
243265005428	Homeodomain-like domain; Region: HTH_23; pfam13384
243265005429	Winged helix-turn helix; Region: HTH_29; pfam13551
243265005430	Winged helix-turn helix; Region: HTH_33; pfam13592
243265005431	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265005432	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265005433	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265005434	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
243265005435	putative active site [active]
243265005436	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
243265005437	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265005438	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
243265005439	GTP-binding protein YchF; Reviewed; Region: PRK09601
243265005440	YchF GTPase; Region: YchF; cd01900
243265005441	G1 box; other site
243265005442	GTP/Mg2+ binding site [chemical binding]; other site
243265005443	Switch I region; other site
243265005444	G2 box; other site
243265005445	Switch II region; other site
243265005446	G3 box; other site
243265005447	G4 box; other site
243265005448	G5 box; other site
243265005449	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
243265005450	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
243265005451	putative active site [active]
243265005452	catalytic residue [active]
243265005453	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265005454	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
243265005455	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
243265005456	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
243265005457	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
243265005458	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
243265005459	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
243265005460	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
243265005461	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
243265005462	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
243265005463	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
243265005464	Protein of unknown function (DUF2583); Region: DUF2583; pfam10762
243265005465	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
243265005466	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
243265005467	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265005468	active site
243265005469	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
243265005470	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
243265005471	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
243265005472	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
243265005473	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
243265005474	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
243265005475	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
243265005476	tRNA; other site
243265005477	putative tRNA binding site [nucleotide binding]; other site
243265005478	putative NADP binding site [chemical binding]; other site
243265005479	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
243265005480	peptide chain release factor 1; Validated; Region: prfA; PRK00591
243265005481	This domain is found in peptide chain release factors; Region: PCRF; smart00937
243265005482	RF-1 domain; Region: RF-1; pfam00472
243265005483	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
243265005484	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265005485	hypothetical protein; Provisional; Region: PRK10941
243265005486	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
243265005487	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
243265005488	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
243265005489	putative transporter; Provisional; Region: PRK11660
243265005490	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
243265005491	Sulfate transporter family; Region: Sulfate_transp; pfam00916
243265005492	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
243265005493	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
243265005494	classical (c) SDRs; Region: SDR_c; cd05233
243265005495	NAD(P) binding site [chemical binding]; other site
243265005496	active site
243265005497	Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192
243265005498	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
243265005499	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
243265005500	Acyl-CoA reductase (LuxC); Region: LuxC; pfam05893
243265005501	Acyl-CoA reductase LuxC; Region: ALDH_Acyl-CoA-Red_LuxC; cd07080
243265005502	putative catalytic cysteine [active]
243265005503	acyl transferase; Provisional; Region: luxD; PRK13604
243265005504	Acyl transferase; Region: Acyl_transf_2; pfam02273
243265005505	Alkanal monooxygenase are flavin monoxygenases. Molecular oxygen is activated by reaction with reduced flavin mononucleotide (FMNH2) and reacts with an aldehyde to yield the carboxylic acid, oxidized flavin (FMN) and a blue-green light. Bacterial...; Region: Alkanal_monooxygenase; cd01096
243265005506	Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296
243265005507	dimer interface [polypeptide binding]; other site
243265005508	non-prolyl cis peptide bond; other site
243265005509	active site
243265005510	Alkanal monooxygenase are flavin monoxygenases. Molecular oxygen is activated by reaction with reduced flavin mononucleotide (FMNH2) and reacts with an aldehyde to yield the carboxylic acid, oxidized flavin (FMN) and a blue-green light. Bacterial...; Region: Alkanal_monooxygenase; cd01096
243265005511	Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296
243265005512	dimer interface [polypeptide binding]; other site
243265005513	non-prolyl cis peptide bond; other site
243265005514	active site
243265005515	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
243265005516	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
243265005517	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265005518	non-specific DNA binding site [nucleotide binding]; other site
243265005519	salt bridge; other site
243265005520	sequence-specific DNA binding site [nucleotide binding]; other site
243265005521	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
243265005522	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
243265005523	putative ligand binding site [chemical binding]; other site
243265005524	NAD binding site [chemical binding]; other site
243265005525	dimerization interface [polypeptide binding]; other site
243265005526	catalytic site [active]
243265005527	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
243265005528	lipoprotein; Provisional; Region: PRK10598
243265005529	multidrug resistance protein MdtH; Provisional; Region: PRK11646
243265005530	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265005531	putative substrate translocation pore; other site
243265005532	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
243265005533	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
243265005534	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
243265005535	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
243265005536	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
243265005537	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
243265005538	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
243265005539	active site
243265005540	HIGH motif; other site
243265005541	KMSK motif region; other site
243265005542	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
243265005543	tRNA binding surface [nucleotide binding]; other site
243265005544	anticodon binding site; other site
243265005545	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
243265005546	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
243265005547	hypothetical protein; Provisional; Region: PRK03757
243265005548	PA-IL-like protein; Region: PA-IL; pfam07828
243265005549	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
243265005550	putative metal binding site [ion binding]; other site
243265005551	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265005552	non-specific DNA binding site [nucleotide binding]; other site
243265005553	salt bridge; other site
243265005554	sequence-specific DNA binding site [nucleotide binding]; other site
243265005555	Truncated gene. Some similarities with Unknown protein YecM of Escherichia coli
243265005556	copper homeostasis protein CutC; Provisional; Region: PRK11572
243265005557	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265005558	S-adenosylmethionine binding site [chemical binding]; other site
243265005559	Methyltransferase domain; Region: Methyltransf_31; pfam13847
243265005560	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265005561	S-adenosylmethionine binding site [chemical binding]; other site
243265005562	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
243265005563	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
243265005564	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
243265005565	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
243265005566	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
243265005567	dimer interface [polypeptide binding]; other site
243265005568	anticodon binding site; other site
243265005569	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
243265005570	homodimer interface [polypeptide binding]; other site
243265005571	motif 1; other site
243265005572	active site
243265005573	motif 2; other site
243265005574	GAD domain; Region: GAD; pfam02938
243265005575	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
243265005576	active site
243265005577	motif 3; other site
243265005578	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
243265005579	nudix motif; other site
243265005580	hypothetical protein; Validated; Region: PRK00110
243265005581	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
243265005582	active site
243265005583	putative DNA-binding cleft [nucleotide binding]; other site
243265005584	dimer interface [polypeptide binding]; other site
243265005585	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
243265005586	RuvA N terminal domain; Region: RuvA_N; pfam01330
243265005587	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
243265005588	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
243265005589	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265005590	Walker A motif; other site
243265005591	ATP binding site [chemical binding]; other site
243265005592	Walker B motif; other site
243265005593	arginine finger; other site
243265005594	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
243265005595	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
243265005596	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265005597	ABC-ATPase subunit  interface; other site
243265005598	dimer interface [polypeptide binding]; other site
243265005599	putative PBP binding regions; other site
243265005600	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
243265005601	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
243265005602	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
243265005603	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
243265005604	metal binding site [ion binding]; metal-binding site
243265005605	putative peptidase; Provisional; Region: PRK11649
243265005606	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
243265005607	Peptidase family M23; Region: Peptidase_M23; pfam01551
243265005608	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
243265005609	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
243265005610	putative acyl-acceptor binding pocket; other site
243265005611	pyruvate kinase; Provisional; Region: PRK05826
243265005612	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
243265005613	domain interfaces; other site
243265005614	active site
243265005615	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265005616	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265005617	Phage Tail Collar Domain; Region: Collar; pfam07484
243265005618	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
243265005619	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
243265005620	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
243265005621	putative active site [active]
243265005622	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
243265005623	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
243265005624	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
243265005625	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
243265005626	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
243265005627	HipA-like C-terminal domain; Region: HipA_C; pfam07804
243265005628	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265005629	non-specific DNA binding site [nucleotide binding]; other site
243265005630	salt bridge; other site
243265005631	sequence-specific DNA binding site [nucleotide binding]; other site
243265005632	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
243265005633	homotrimer interaction site [polypeptide binding]; other site
243265005634	putative active site [active]
243265005635	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
243265005636	DEAD/DEAH box helicase; Region: DEAD; pfam00270
243265005637	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
243265005638	Protein of unknown function (DUF1044); Region: DUF1044; pfam06296
243265005639	Predicted transcriptional regulator [Transcription]; Region: COG2944
243265005640	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265005641	non-specific DNA binding site [nucleotide binding]; other site
243265005642	salt bridge; other site
243265005643	sequence-specific DNA binding site [nucleotide binding]; other site
243265005644	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
243265005645	Glycoprotease family; Region: Peptidase_M22; pfam00814
243265005646	Outer membrane lipoprotein Slp family; Region: Slp; pfam03843
243265005647	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
243265005648	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265005649	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
243265005650	acyl-activating enzyme (AAE) consensus motif; other site
243265005651	putative AMP binding site [chemical binding]; other site
243265005652	putative active site [active]
243265005653	putative CoA binding site [chemical binding]; other site
243265005654	ribonuclease D; Provisional; Region: PRK10829
243265005655	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
243265005656	catalytic site [active]
243265005657	putative active site [active]
243265005658	putative substrate binding site [chemical binding]; other site
243265005659	HRDC domain; Region: HRDC; pfam00570
243265005660	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
243265005661	cell division inhibitor MinD; Provisional; Region: PRK10818
243265005662	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
243265005663	Switch I; other site
243265005664	Switch II; other site
243265005665	septum formation inhibitor; Reviewed; Region: minC; PRK03511
243265005666	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
243265005667	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
243265005668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
243265005669	hypothetical protein; Provisional; Region: PRK10691
243265005670	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
243265005671	hypothetical protein; Provisional; Region: PRK05170
243265005672	heat-inducible protein; Provisional; Region: PRK10449
243265005673	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
243265005674	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
243265005675	putative ligand binding site [chemical binding]; other site
243265005676	putative NAD binding site [chemical binding]; other site
243265005677	catalytic site [active]
243265005678	hypothetical protein; Provisional; Region: PRK10695
243265005679	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
243265005680	Protein of unknown function (DUF1318); Region: DUF1318; pfam07027
243265005681	azoreductase; Reviewed; Region: PRK00170
243265005682	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
243265005683	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
243265005684	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265005685	ATP binding site [chemical binding]; other site
243265005686	putative Mg++ binding site [ion binding]; other site
243265005687	This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  This...; Region: NifX_NifB; cl00252
243265005688	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265005689	nucleotide binding region [chemical binding]; other site
243265005690	ATP-binding site [chemical binding]; other site
243265005691	Helicase associated domain (HA2); Region: HA2; pfam04408
243265005692	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
243265005693	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
243265005694	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
243265005695	Post-segregation antitoxin CcdA; Region: CcdA; cl02188
243265005696	CcdB protein; Region: CcdB; cl03380
243265005697	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
243265005698	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
243265005699	PapC N-terminal domain; Region: PapC_N; pfam13954
243265005700	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
243265005701	PapC C-terminal domain; Region: PapC_C; pfam13953
243265005702	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
243265005703	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265005704	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265005705	Fimbrial protein; Region: Fimbrial; cl01416
243265005706	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
243265005707	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
243265005708	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK06816
243265005709	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
243265005710	dimer interface [polypeptide binding]; other site
243265005711	active site
243265005712	acyl carrier protein; Provisional; Region: acpP; PRK00982
243265005713	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
243265005714	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
243265005715	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
243265005716	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
243265005717	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
243265005718	ligand binding site [chemical binding]; other site
243265005719	homodimer interface [polypeptide binding]; other site
243265005720	NAD(P) binding site [chemical binding]; other site
243265005721	trimer interface B [polypeptide binding]; other site
243265005722	trimer interface A [polypeptide binding]; other site
243265005723	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
243265005724	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
243265005725	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
243265005726	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
243265005727	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
243265005728	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
243265005729	alpha-gamma subunit interface [polypeptide binding]; other site
243265005730	beta-gamma subunit interface [polypeptide binding]; other site
243265005731	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
243265005732	alpha-beta subunit interface [polypeptide binding]; other site
243265005733	urease subunit alpha; Reviewed; Region: ureC; PRK13309
243265005734	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
243265005735	subunit interactions [polypeptide binding]; other site
243265005736	active site
243265005737	flap region; other site
243265005738	urease accessory protein UreE; Provisional; Region: ureE; PRK14711
243265005739	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
243265005740	dimer interface [polypeptide binding]; other site
243265005741	catalytic residues [active]
243265005742	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
243265005743	UreF; Region: UreF; pfam01730
243265005744	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
243265005745	UreD urease accessory protein; Region: UreD; pfam01774
243265005746	universal stress protein UspE; Provisional; Region: PRK11175
243265005747	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
243265005748	Ligand Binding Site [chemical binding]; other site
243265005749	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
243265005750	Ligand Binding Site [chemical binding]; other site
243265005751	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
243265005752	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
243265005753	ligand binding site [chemical binding]; other site
243265005754	flexible hinge region; other site
243265005755	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
243265005756	putative switch regulator; other site
243265005757	non-specific DNA interactions [nucleotide binding]; other site
243265005758	DNA binding site [nucleotide binding]
243265005759	sequence specific DNA binding site [nucleotide binding]; other site
243265005760	putative cAMP binding site [chemical binding]; other site
243265005761	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265005762	active site
243265005763	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
243265005764	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
243265005765	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265005766	motif II; other site
243265005767	Protein of unknown function, DUF606; Region: DUF606; pfam04657
243265005768	Protein of unknown function, DUF606; Region: DUF606; pfam04657
243265005769	Protein of unknown function (DUF4243); Region: DUF4243; pfam14027
243265005770	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265005771	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265005772	acyl-activating enzyme (AAE) consensus motif; other site
243265005773	AMP binding site [chemical binding]; other site
243265005774	This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142
243265005775	putative FMN binding site [chemical binding]; other site
243265005776	NADPH bind site [chemical binding]; other site
243265005777	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265005778	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265005779	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
243265005780	Truncated gene. Some similarities with probable kfr protein of Escherichia coli
243265005781	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265005782	non-specific DNA binding site [nucleotide binding]; other site
243265005783	salt bridge; other site
243265005784	sequence-specific DNA binding site [nucleotide binding]; other site
243265005785	Truncated gene. Some similarities with N-terminal region of 2-hydroxypenta-2,4-dienoate hydratase
243265005786	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
243265005787	diaminobutyrate--2-oxoglutarate aminotransferase; Validated; Region: PRK09264
243265005788	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265005789	inhibitor-cofactor binding pocket; inhibition site
243265005790	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265005791	catalytic residue [active]
243265005792	A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; cl17448
243265005793	molybdopterin synthase sulfurylase MoeB; Region: moeB; TIGR02355
243265005794	ThiF family; Region: ThiF; pfam00899
243265005795	ATP binding site [chemical binding]; other site
243265005796	substrate interface [chemical binding]; other site
243265005797	Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668
243265005798	active site
243265005799	iron coordination sites [ion binding]; other site
243265005800	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265005801	Coenzyme A binding pocket [chemical binding]; other site
243265005802	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
243265005803	metal binding site [ion binding]; metal-binding site
243265005804	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
243265005805	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
243265005806	putative active site [active]
243265005807	putative metal binding site [ion binding]; other site
243265005808	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265005809	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
243265005810	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
243265005811	ATP-grasp domain; Region: ATP-grasp_4; cl17255
243265005812	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
243265005813	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265005814	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265005815	putative substrate translocation pore; other site
243265005816	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265005817	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
243265005818	Amidase; Region: Amidase; cl11426
243265005819	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
243265005820	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
243265005821	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
243265005822	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
243265005823	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265005824	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
243265005825	putative dimerization interface [polypeptide binding]; other site
243265005826	putative substrate binding pocket [chemical binding]; other site
243265005827	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
243265005828	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
243265005829	iron-sulfur cluster [ion binding]; other site
243265005830	[2Fe-2S] cluster binding site [ion binding]; other site
243265005831	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
243265005832	beta subunit interface [polypeptide binding]; other site
243265005833	alpha subunit interface [polypeptide binding]; other site
243265005834	active site
243265005835	substrate binding site [chemical binding]; other site
243265005836	Fe binding site [ion binding]; other site
243265005837	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
243265005838	inter-subunit interface; other site
243265005839	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
243265005840	[2Fe-2S] cluster binding site [ion binding]; other site
243265005841	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
243265005842	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
243265005843	NAD binding site [chemical binding]; other site
243265005844	active site
243265005845	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
243265005846	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
243265005847	putative active site [active]
243265005848	Fe(II) binding site [ion binding]; other site
243265005849	putative dimer interface [polypeptide binding]; other site
243265005850	putative tetramer interface [polypeptide binding]; other site
243265005851	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
243265005852	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
243265005853	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
243265005854	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
243265005855	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
243265005856	peptide binding site [polypeptide binding]; other site
243265005857	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
243265005858	Walker A/P-loop; other site
243265005859	ATP binding site [chemical binding]; other site
243265005860	ABC transporter signature motif; other site
243265005861	Walker B; other site
243265005862	D-loop; other site
243265005863	H-loop/switch region; other site
243265005864	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
243265005865	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
243265005866	dimer interface [polypeptide binding]; other site
243265005867	active site
243265005868	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
243265005869	Phosphopantetheine attachment site; Region: PP-binding; cl09936
243265005870	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265005871	RHS Repeat; Region: RHS_repeat; cl11982
243265005872	RHS Repeat; Region: RHS_repeat; cl11982
243265005873	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265005874	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265005875	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265005876	putative substrate translocation pore; other site
243265005877	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265005878	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265005879	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
243265005880	dimerization interface [polypeptide binding]; other site
243265005881	substrate binding pocket [chemical binding]; other site
243265005882	MarR family; Region: MarR_2; cl17246
243265005883	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
243265005884	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
243265005885	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
243265005886	AAA domain; Region: AAA_26; pfam13500
243265005887	Truncated transposase, IS630 family (ISPlu3-p)
243265005888	Aegerolysin; Region: Aegerolysin; pfam06355
243265005889	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
243265005890	active site
243265005891	metal binding site [ion binding]; metal-binding site
243265005892	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
243265005893	hypothetical protein; Provisional; Region: PRK13659
243265005894	malonic semialdehyde reductase; Provisional; Region: PRK10538
243265005895	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
243265005896	putative NAD(P) binding site [chemical binding]; other site
243265005897	homodimer interface [polypeptide binding]; other site
243265005898	homotetramer interface [polypeptide binding]; other site
243265005899	active site
243265005900	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
243265005901	active sites [active]
243265005902	tetramer interface [polypeptide binding]; other site
243265005903	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
243265005904	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
243265005905	active site
243265005906	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
243265005907	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
243265005908	aromatic chitin/cellulose binding site residues [chemical binding]; other site
243265005909	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
243265005910	hypothetical protein; Provisional; Region: PRK06847
243265005911	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
243265005912	Methyltransferase domain; Region: Methyltransf_31; pfam13847
243265005913	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265005914	S-adenosylmethionine binding site [chemical binding]; other site
243265005915	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
243265005916	nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of...; Region: nylC_like; cd02252
243265005917	putative active site pocket [active]
243265005918	cleavage site
243265005919	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
243265005920	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
243265005921	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510
243265005922	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
243265005923	hydroxyproline-2-epimerase; Provisional; Region: PRK13970
243265005924	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
243265005925	PAS fold; Region: PAS_4; pfam08448
243265005926	Helix-turn-helix domain; Region: HTH_18; pfam12833
243265005927	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265005928	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
243265005929	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
243265005930	inhibitor site; inhibition site
243265005931	active site
243265005932	dimer interface [polypeptide binding]; other site
243265005933	catalytic residue [active]
243265005934	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
243265005935	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
243265005936	dimer interface [polypeptide binding]; other site
243265005937	NADP binding site [chemical binding]; other site
243265005938	catalytic residues [active]
243265005939	amino acid transporter; Region: 2A0306; TIGR00909
243265005940	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
243265005941	active site clefts [active]
243265005942	zinc binding site [ion binding]; other site
243265005943	dimer interface [polypeptide binding]; other site
243265005944	Cupin domain; Region: Cupin_2; cl17218
243265005945	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
243265005946	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
243265005947	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
243265005948	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265005949	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265005950	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
243265005951	L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253
243265005952	homodimer interface [polypeptide binding]; other site
243265005953	homotetramer interface [polypeptide binding]; other site
243265005954	active site pocket [active]
243265005955	cleavage site
243265005956	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
243265005957	beta alanine--pyruvate transaminase; Provisional; Region: PRK09221
243265005958	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265005959	inhibitor-cofactor binding pocket; inhibition site
243265005960	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265005961	catalytic residue [active]
243265005962	The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members...; Region: MopB_Acetylene-hydratase; cd02759
243265005963	putative [Fe4-S4] binding site [ion binding]; other site
243265005964	putative molybdopterin cofactor binding site [chemical binding]; other site
243265005965	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
243265005966	The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members...; Region: MopB_Acetylene-hydratase; cd02759
243265005967	The MopB_CT_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. This...; Region: MopB_CT_Acetylene-hydratase; cd02781
243265005968	putative molybdopterin cofactor binding site; other site
243265005969	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
243265005970	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
243265005971	FAD binding pocket [chemical binding]; other site
243265005972	FAD binding motif [chemical binding]; other site
243265005973	phosphate binding motif [ion binding]; other site
243265005974	beta-alpha-beta structure motif; other site
243265005975	NAD binding pocket [chemical binding]; other site
243265005976	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
243265005977	catalytic loop [active]
243265005978	iron binding site [ion binding]; other site
243265005979	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
243265005980	active site
243265005981	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
243265005982	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
243265005983	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
243265005984	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
243265005985	substrate binding pocket [chemical binding]; other site
243265005986	DNA binding domain, excisionase family; Region: excise; TIGR01764
243265005987	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
243265005988	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
243265005989	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
243265005990	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
243265005991	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
243265005992	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
243265005993	beta-galactosidase; Region: BGL; TIGR03356
243265005994	Transcriptional regulators [Transcription]; Region: PurR; COG1609
243265005995	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
243265005996	putative dimerization interface [polypeptide binding]; other site
243265005997	putative ligand binding site [chemical binding]; other site
243265005998	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
243265005999	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265006000	xylose isomerase; Provisional; Region: PRK05474
243265006001	xylose isomerase; Region: xylose_isom_A; TIGR02630
243265006002	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_11; cd07261
243265006003	putative dimer interface [polypeptide binding]; other site
243265006004	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
243265006005	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
243265006006	CcdB protein; Region: CcdB; pfam01845
243265006007	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
243265006008	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
243265006009	Helix-turn-helix domain; Region: HTH_38; pfam13936
243265006010	Homeodomain-like domain; Region: HTH_32; pfam13565
243265006011	Integrase core domain; Region: rve; pfam00665
243265006012	Protein of unknown function (DUF1778); Region: DUF1778; cl01845
243265006013	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265006014	substrate binding pocket [chemical binding]; other site
243265006015	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
243265006016	membrane-bound complex binding site; other site
243265006017	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265006018	substrate binding pocket [chemical binding]; other site
243265006019	membrane-bound complex binding site; other site
243265006020	hinge residues; other site
243265006021	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265006022	dimer interface [polypeptide binding]; other site
243265006023	phosphorylation site [posttranslational modification]
243265006024	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265006025	ATP binding site [chemical binding]; other site
243265006026	Mg2+ binding site [ion binding]; other site
243265006027	G-X-G motif; other site
243265006028	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265006029	active site
243265006030	phosphorylation site [posttranslational modification]
243265006031	intermolecular recognition site; other site
243265006032	dimerization interface [polypeptide binding]; other site
243265006033	Hpt domain; Region: Hpt; pfam01627
243265006034	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265006035	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265006036	active site
243265006037	phosphorylation site [posttranslational modification]
243265006038	intermolecular recognition site; other site
243265006039	dimerization interface [polypeptide binding]; other site
243265006040	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265006041	DNA binding residues [nucleotide binding]
243265006042	dimerization interface [polypeptide binding]; other site
243265006043	MASE1; Region: MASE1; cl17823
243265006044	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
243265006045	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265006046	Walker A motif; other site
243265006047	ATP binding site [chemical binding]; other site
243265006048	Walker B motif; other site
243265006049	arginine finger; other site
243265006050	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265006051	Walker A motif; other site
243265006052	ATP binding site [chemical binding]; other site
243265006053	Walker B motif; other site
243265006054	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
243265006055	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
243265006056	type IV / VI secretion system protein, DotU family; Region: IV_VI_DotU; TIGR03349
243265006057	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
243265006058	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
243265006059	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
243265006060	type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363
243265006061	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
243265006062	PAAR motif; Region: PAAR_motif; pfam05488
243265006063	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
243265006064	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265006065	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265006066	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
243265006067	type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359
243265006068	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
243265006069	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
243265006070	Protein of unknown function (DUF796); Region: DUF796; pfam05638
243265006071	type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355
243265006072	Protein of unknown function (DUF877); Region: DUF877; pfam05943
243265006073	type VI secretion protein, VC_A0107 family; Region: VI_chp_5; TIGR03358
243265006074	Phage Tail Collar Domain; Region: Collar; pfam07484
243265006075	Truncated gene. Some similarities with plasmid stability-like protein
243265006076	Predicted transcriptional regulator [Transcription]; Region: COG3905
243265006077	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
243265006078	Truncated gene. Some weak similarities with plasmid stability-like protein
243265006079	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265006080	non-specific DNA binding site [nucleotide binding]; other site
243265006081	sequence-specific DNA binding site [nucleotide binding]; other site
243265006082	salt bridge; other site
243265006083	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
243265006084	Truncated gene. Some similarities with C-terminal region of DNA-invertase/resolvase
243265006085	Truncated gene. Some similarities with N-terminal region of  recombinase, resolvase
243265006086	Truncated gene. Some similarities with beta-lactamase of Yersinia enterocolitica
243265006087	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
243265006088	nucleophilic elbow; other site
243265006089	catalytic triad; other site
243265006090	Homeodomain-like domain; Region: HTH_23; pfam13384
243265006091	Winged helix-turn helix; Region: HTH_29; pfam13551
243265006092	Winged helix-turn helix; Region: HTH_33; pfam13592
243265006093	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265006094	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265006095	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
243265006096	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265006097	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
243265006098	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265006099	N-terminal plug; other site
243265006100	ligand-binding site [chemical binding]; other site
243265006101	siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718
243265006102	muropeptide transporter; Validated; Region: ampG; cl17669
243265006103	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
243265006104	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265006105	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265006106	Walker A/P-loop; other site
243265006107	ATP binding site [chemical binding]; other site
243265006108	Q-loop/lid; other site
243265006109	ABC transporter signature motif; other site
243265006110	Walker B; other site
243265006111	D-loop; other site
243265006112	H-loop/switch region; other site
243265006113	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265006114	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265006115	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
243265006116	Walker A/P-loop; other site
243265006117	ATP binding site [chemical binding]; other site
243265006118	Q-loop/lid; other site
243265006119	ABC transporter signature motif; other site
243265006120	Walker B; other site
243265006121	D-loop; other site
243265006122	H-loop/switch region; other site
243265006123	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
243265006124	Condensation domain; Region: Condensation; pfam00668
243265006125	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265006126	Nonribosomal peptide synthase; Region: NRPS; pfam08415
243265006127	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
243265006128	acyl-activating enzyme (AAE) consensus motif; other site
243265006129	AMP binding site [chemical binding]; other site
243265006130	Methyltransferase domain; Region: Methyltransf_12; pfam08242
243265006131	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265006132	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265006133	Condensation domain; Region: Condensation; pfam00668
243265006134	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265006135	Nonribosomal peptide synthase; Region: NRPS; pfam08415
243265006136	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265006137	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
243265006138	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
243265006139	active site
243265006140	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
243265006141	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
243265006142	ketoreductase (KR) and fatty acid synthase (FAS), complex (x) SDRs; Region: KR_FAS_SDR_x; cd05274
243265006143	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
243265006144	NADP binding site [chemical binding]; other site
243265006145	active site
243265006146	Condensation domain; Region: Condensation; pfam00668
243265006147	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265006148	Nonribosomal peptide synthase; Region: NRPS; pfam08415
243265006149	Methyltransferase domain; Region: Methyltransf_23; pfam13489
243265006150	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265006151	S-adenosylmethionine binding site [chemical binding]; other site
243265006152	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265006153	Condensation domain; Region: Condensation; pfam00668
243265006154	Nonribosomal peptide synthase; Region: NRPS; pfam08415
243265006155	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
243265006156	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265006157	acyl-activating enzyme (AAE) consensus motif; other site
243265006158	AMP binding site [chemical binding]; other site
243265006159	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265006160	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
243265006161	thiazolinyl imide reductase; Region: thiaz-red; TIGR01761
243265006162	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
243265006163	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
243265006164	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
243265006165	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
243265006166	acyl-activating enzyme (AAE) consensus motif; other site
243265006167	active site
243265006168	AMP binding site [chemical binding]; other site
243265006169	substrate binding site [chemical binding]; other site
243265006170	salicylate synthase; Region: salicyl_syn; TIGR03494
243265006171	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
243265006172	Cupin; Region: Cupin_1; smart00835
243265006173	Thermophilic glucose-6-phosphate isomerase and related metalloenzymes [Carbohydrate transport and metabolism / General function prediction only]; Region: COG2140
243265006174	Cupin; Region: Cupin_1; smart00835
243265006175	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
243265006176	Acyltransferase family; Region: Acyl_transf_3; pfam01757
243265006177	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
243265006178	active site
243265006179	catalytic triad [active]
243265006180	oxyanion hole [active]
243265006181	Truncated gene. N-terminal region weakly similar to transposase
243265006182	Antitoxin ParD; Region: ParD; pfam09386
243265006183	Truncated gene. Similar to N-terminal region of plasmid stabilization protein ParE
243265006184	Truncated gene. Highly similar to C-terminal region of plasmid stabilization protein ParE
243265006185	Truncated gene. Weakly similar to N-terminal region of insecticidal toxin complex protein TccB from Photorhabdus luminescens
243265006186	Truncated gene. Similar to central region of insecticidal toxin complex protein TccB from Photorhabdus luminescens
243265006187	Truncated gene. Similar to C-terminal region of insecticidal toxin complex protein TccB from Photorhabdus luminescens
243265006188	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
243265006189	active site
243265006190	OsmC-like protein; Region: OsmC; pfam02566
243265006191	Domain of unknown function DUF29; Region: DUF29; pfam01724
243265006192	tyrosine transporter TyrP; Provisional; Region: PRK15132
243265006193	aromatic amino acid transport protein; Region: araaP; TIGR00837
243265006194	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
243265006195	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265006196	catalytic residue [active]
243265006197	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
243265006198	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
243265006199	NAD(P) binding site [chemical binding]; other site
243265006200	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
243265006201	classical (c) SDRs; Region: SDR_c; cd05233
243265006202	NAD(P) binding site [chemical binding]; other site
243265006203	active site
243265006204	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
243265006205	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
243265006206	Protein of unknown function (DUF805); Region: DUF805; pfam05656
243265006207	4-aminobutyrate aminotransferase; Provisional; Region: PRK07495
243265006208	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265006209	inhibitor-cofactor binding pocket; inhibition site
243265006210	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265006211	catalytic residue [active]
243265006212	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
243265006213	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
243265006214	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
243265006215	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
243265006216	tetrameric interface [polypeptide binding]; other site
243265006217	NAD binding site [chemical binding]; other site
243265006218	catalytic residues [active]
243265006219	substrate binding site [chemical binding]; other site
243265006220	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
243265006221	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
243265006222	peptide binding site [polypeptide binding]; other site
243265006223	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
243265006224	NADH(P)-binding; Region: NAD_binding_10; pfam13460
243265006225	NADP binding site [chemical binding]; other site
243265006226	Chitin binding domain; Region: Chitin_bind_3; pfam03067
243265006227	Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_1; cd09996
243265006228	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
243265006229	active site
243265006230	Zn binding site [ion binding]; other site
243265006231	DNA replication terminus site-binding protein; Region: rep_term_tus; TIGR02648
243265006232	Protein of unknown function (DUF2384); Region: DUF2384; cl17718
243265006233	putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293
243265006234	RES domain; Region: RES; cl02411
243265006235	fumarate hydratase; Reviewed; Region: fumC; PRK00485
243265006236	Class II fumarases; Region: Fumarase_classII; cd01362
243265006237	active site
243265006238	tetramer interface [polypeptide binding]; other site
243265006239	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
243265006240	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
243265006241	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
243265006242	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
243265006243	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
243265006244	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
243265006245	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
243265006246	active site
243265006247	purine riboside binding site [chemical binding]; other site
243265006248	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
243265006249	PemK-like protein; Region: PemK; cl00995
243265006250	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
243265006251	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: VapC; COG1487
243265006252	putative active site [active]
243265006253	Uncharacterized protein conserved in bacteria (DUF2191); Region: DUF2191; pfam09957
243265006254	Truncated transposase.
243265006255	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
243265006256	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
243265006257	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
243265006258	putative oxidoreductase; Provisional; Region: PRK11579
243265006259	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
243265006260	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
243265006261	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
243265006262	electron transport complex protein RsxA; Provisional; Region: PRK05151
243265006263	electron transport complex protein RnfB; Provisional; Region: PRK05113
243265006264	Putative Fe-S cluster; Region: FeS; pfam04060
243265006265	4Fe-4S binding domain; Region: Fer4; pfam00037
243265006266	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
243265006267	SLBB domain; Region: SLBB; pfam10531
243265006268	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
243265006269	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
243265006270	electron transport complex protein RnfG; Validated; Region: PRK01908
243265006271	electron transport complex RsxE subunit; Provisional; Region: PRK12405
243265006272	endonuclease III; Provisional; Region: PRK10702
243265006273	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
243265006274	minor groove reading motif; other site
243265006275	helix-hairpin-helix signature motif; other site
243265006276	substrate binding pocket [chemical binding]; other site
243265006277	active site
243265006278	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
243265006279	exoribonuclease II; Provisional; Region: PRK05054
243265006280	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
243265006281	RNB domain; Region: RNB; pfam00773
243265006282	S1 RNA binding domain; Region: S1; pfam00575
243265006283	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; cl17313
243265006284	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265006285	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265006286	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265006287	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
243265006288	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
243265006289	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265006290	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265006291	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265006292	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
243265006293	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
243265006294	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
243265006295	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265006296	Walker A motif; other site
243265006297	ATP binding site [chemical binding]; other site
243265006298	Walker B motif; other site
243265006299	arginine finger; other site
243265006300	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
243265006301	C-terminal region of Pasteurella multocida toxin residues 569-1285; Region: PMT_C; pfam11647
243265006302	Yersinia/Haemophilus virulence surface antigen; Region: Peptidase_C58; pfam03543
243265006303	Truncated gene. Highly similar to C-terminal region of transposase
243265006304	Nucleoside diphosphate kinase; Region: NDK; pfam00334
243265006305	active site
243265006306	multimer interface [polypeptide binding]; other site
243265006307	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
243265006308	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
243265006309	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265006310	catalytic residue [active]
243265006311	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
243265006312	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265006313	acyl-activating enzyme (AAE) consensus motif; other site
243265006314	AMP binding site [chemical binding]; other site
243265006315	active site
243265006316	CoA binding site [chemical binding]; other site
243265006317	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
243265006318	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
243265006319	active site
243265006321	Homeodomain-like domain; Region: HTH_23; pfam13384
243265006322	Winged helix-turn helix; Region: HTH_29; pfam13551
243265006323	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265006325	Truncated gene. Weakly similar to transposase
243265006326	Truncated gene. Weakly similar to transposase
243265006327	Homeodomain-like domain; Region: HTH_23; pfam13384
243265006328	Winged helix-turn helix; Region: HTH_29; pfam13551
243265006329	Winged helix-turn helix; Region: HTH_33; pfam13592
243265006330	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265006331	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265006332	Fic family protein [Function unknown]; Region: COG3177
243265006333	Fic/DOC family; Region: Fic; pfam02661
243265006334	HipA N-terminal domain; Region: Couple_hipA; pfam13657
243265006335	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
243265006336	HipA-like N-terminal domain; Region: HipA_N; pfam07805
243265006337	HipA-like C-terminal domain; Region: HipA_C; pfam07804
243265006338	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558
243265006339	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
243265006340	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
243265006341	translation initiation factor Sui1; Validated; Region: PRK06824
243265006342	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
243265006343	putative rRNA binding site [nucleotide binding]; other site
243265006344	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
243265006345	active site
243265006346	dimer interface [polypeptide binding]; other site
243265006347	tetratricopeptide repeat protein; Provisional; Region: PRK11788
243265006348	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
243265006349	binding surface
243265006350	TPR motif; other site
243265006351	Predicted membrane protein [Function unknown]; Region: COG3771
243265006352	Truncated gene. Some similarities with phosphatidylglycerophosphatase B
243265006353	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
243265006354	dimerization interface [polypeptide binding]; other site
243265006355	active site
243265006356	aconitate hydratase; Validated; Region: PRK09277
243265006357	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
243265006358	substrate binding site [chemical binding]; other site
243265006359	ligand binding site [chemical binding]; other site
243265006360	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
243265006361	substrate binding site [chemical binding]; other site
243265006362	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
243265006363	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265006364	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
243265006365	dimerization interface [polypeptide binding]; other site
243265006366	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
243265006367	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
243265006368	active site
243265006369	interdomain interaction site; other site
243265006370	putative metal-binding site [ion binding]; other site
243265006371	nucleotide binding site [chemical binding]; other site
243265006372	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
243265006373	domain I; other site
243265006374	DNA binding groove [nucleotide binding]
243265006375	phosphate binding site [ion binding]; other site
243265006376	domain II; other site
243265006377	domain III; other site
243265006378	nucleotide binding site [chemical binding]; other site
243265006379	catalytic site [active]
243265006380	domain IV; other site
243265006381	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
243265006382	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
243265006383	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
243265006384	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
243265006385	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
243265006386	putative inner membrane peptidase; Provisional; Region: PRK11778
243265006387	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
243265006388	tandem repeat interface [polypeptide binding]; other site
243265006389	oligomer interface [polypeptide binding]; other site
243265006390	active site residues [active]
243265006391	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265006392	RHS Repeat; Region: RHS_repeat; pfam05593
243265006393	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265006394	Inclusion body protein; Region: PixA; pfam12306
243265006395	Truncated gene. Similar to N-terminal region of transposase, IS110 family (ISPlu13-p)
243265006396	Truncated gene. Similar to C-terminal region of transposase, IS110 family (ISPlu13-p)
243265006397	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
243265006398	Transposase; Region: DEDD_Tnp_IS110; pfam01548
243265006399	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
243265006400	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
243265006401	Chloramphenicol acetyltransferase; Region: CAT; pfam00302
243265006402	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
243265006403	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
243265006404	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
243265006405	NADP binding site [chemical binding]; other site
243265006406	homodimer interface [polypeptide binding]; other site
243265006407	active site
243265006408	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
243265006409	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
243265006410	homodimer interface [polypeptide binding]; other site
243265006411	Walker A motif; other site
243265006412	ATP binding site [chemical binding]; other site
243265006413	hydroxycobalamin binding site [chemical binding]; other site
243265006414	Walker B motif; other site
243265006415	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
243265006416	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
243265006417	RNA binding surface [nucleotide binding]; other site
243265006418	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
243265006419	probable active site [active]
243265006420	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265006421	Possible hemagglutinin (DUF637); Region: DUF637; pfam04830
243265006422	Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; Region: CysPc; cl00051
243265006423	catalytic site [active]
243265006424	hypothetical protein; Provisional; Region: PRK11630
243265006425	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
243265006426	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
243265006427	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
243265006428	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
243265006429	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
243265006430	active site
243265006431	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
243265006432	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
243265006433	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
243265006434	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
243265006435	active site
243265006436	anthranilate synthase component I; Provisional; Region: PRK13564
243265006437	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
243265006438	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
243265006439	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
243265006440	Glutamine amidotransferase class-I; Region: GATase; pfam00117
243265006441	glutamine binding [chemical binding]; other site
243265006442	catalytic triad [active]
243265006443	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
243265006444	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
243265006445	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
243265006446	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
243265006447	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
243265006448	active site
243265006449	ribulose/triose binding site [chemical binding]; other site
243265006450	phosphate binding site [ion binding]; other site
243265006451	substrate (anthranilate) binding pocket [chemical binding]; other site
243265006452	product (indole) binding pocket [chemical binding]; other site
243265006453	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
243265006454	active site
243265006455	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
243265006456	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
243265006457	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265006458	catalytic residue [active]
243265006459	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
243265006460	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
243265006461	substrate binding site [chemical binding]; other site
243265006462	active site
243265006463	catalytic residues [active]
243265006464	heterodimer interface [polypeptide binding]; other site
243265006465	FOG: WD40 repeat [General function prediction only]; Region: COG2319
243265006466	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
243265006467	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265006468	Walker A/P-loop; other site
243265006469	ATP binding site [chemical binding]; other site
243265006470	Q-loop/lid; other site
243265006471	ABC transporter signature motif; other site
243265006472	Walker B; other site
243265006473	D-loop; other site
243265006474	H-loop/switch region; other site
243265006475	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
243265006476	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
243265006477	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
243265006478	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
243265006479	Homeodomain-like domain; Region: HTH_23; pfam13384
243265006480	Winged helix-turn helix; Region: HTH_29; pfam13551
243265006481	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265006482	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265006483	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
243265006484	dimerization interface [polypeptide binding]; other site
243265006485	active site
243265006486	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
243265006487	structural tetrad; other site
243265006488	FOG: WD40 repeat [General function prediction only]; Region: COG2319
243265006489	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
243265006490	structural tetrad; other site
243265006491	Uncharacterized conserved protein [Function unknown]; Region: COG1262
243265006492	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
243265006493	Truncated gene. Some similarities with truncated transposase, IS4 family of Photorhabdus
243265006494	outer membrane protein W; Provisional; Region: PRK10959
243265006495	hypothetical protein; Provisional; Region: PRK02868
243265006496	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
243265006497	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
243265006498	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
243265006499	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
243265006500	Sulfate transporter family; Region: Sulfate_transp; pfam00916
243265006501	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
243265006502	intracellular septation protein A; Reviewed; Region: PRK00259
243265006503	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
243265006504	transport protein TonB; Provisional; Region: PRK10819
243265006505	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
243265006506	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
243265006507	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
243265006508	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
243265006509	putative active site [active]
243265006510	catalytic site [active]
243265006511	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
243265006512	putative active site [active]
243265006513	catalytic site [active]
243265006514	dsDNA-mimic protein; Reviewed; Region: PRK05094
243265006515	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
243265006516	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
243265006517	Walker A/P-loop; other site
243265006518	ATP binding site [chemical binding]; other site
243265006519	Q-loop/lid; other site
243265006520	ABC transporter signature motif; other site
243265006521	Walker B; other site
243265006522	D-loop; other site
243265006523	H-loop/switch region; other site
243265006524	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
243265006525	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
243265006526	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
243265006527	Walker A/P-loop; other site
243265006528	ATP binding site [chemical binding]; other site
243265006529	Q-loop/lid; other site
243265006530	ABC transporter signature motif; other site
243265006531	Walker B; other site
243265006532	D-loop; other site
243265006533	H-loop/switch region; other site
243265006534	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
243265006535	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
243265006536	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
243265006537	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265006538	dimer interface [polypeptide binding]; other site
243265006539	conserved gate region; other site
243265006540	putative PBP binding loops; other site
243265006541	ABC-ATPase subunit interface; other site
243265006542	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
243265006543	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265006544	dimer interface [polypeptide binding]; other site
243265006545	conserved gate region; other site
243265006546	putative PBP binding loops; other site
243265006547	ABC-ATPase subunit interface; other site
243265006548	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
243265006549	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
243265006550	peptide binding site [polypeptide binding]; other site
243265006551	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
243265006552	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
243265006553	peptide binding site [polypeptide binding]; other site
243265006554	hypothetical protein; Provisional; Region: PRK11111
243265006555	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
243265006556	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
243265006557	putative catalytic cysteine [active]
243265006558	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
243265006559	putative active site [active]
243265006560	metal binding site [ion binding]; metal-binding site
243265006561	thymidine kinase; Provisional; Region: PRK04296
243265006562	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
243265006563	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
243265006564	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
243265006565	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
243265006566	putative NAD(P) binding site [chemical binding]; other site
243265006567	active site
243265006568	putative substrate binding site [chemical binding]; other site
243265006569	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
243265006570	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
243265006571	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
243265006572	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
243265006573	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
243265006574	active site
243265006575	tetramer interface; other site
243265006576	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265006577	active site
243265006578	response regulator of RpoS; Provisional; Region: PRK10693
243265006579	phosphorylation site [posttranslational modification]
243265006580	intermolecular recognition site; other site
243265006581	dimerization interface [polypeptide binding]; other site
243265006582	SEC-C motif; Region: SEC-C; pfam02810
243265006583	hypothetical protein; Provisional; Region: PRK04233
243265006584	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
243265006585	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
243265006586	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
243265006587	putative active site [active]
243265006588	putative substrate binding site [chemical binding]; other site
243265006589	putative cosubstrate binding site; other site
243265006590	catalytic site [active]
243265006591	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
243265006592	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
243265006593	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
243265006594	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
243265006595	putative aldolase; Validated; Region: PRK08130
243265006596	intersubunit interface [polypeptide binding]; other site
243265006597	active site
243265006598	Zn2+ binding site [ion binding]; other site
243265006599	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
243265006600	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
243265006601	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
243265006602	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
243265006603	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
243265006604	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
243265006605	putative NAD(P) binding site [chemical binding]; other site
243265006606	active site
243265006607	putative substrate binding site [chemical binding]; other site
243265006608	GntP family permease; Region: GntP_permease; pfam02447
243265006609	fructuronate transporter; Provisional; Region: PRK10034; cl15264
243265006610	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
243265006611	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
243265006612	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265006613	Walker A motif; other site
243265006614	ATP binding site [chemical binding]; other site
243265006615	Walker B motif; other site
243265006616	arginine finger; other site
243265006617	Phage Tail Collar Domain; Region: Collar; pfam07484
243265006618	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
243265006619	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265006620	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265006621	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265006622	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
243265006623	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265006624	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265006625	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
243265006626	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
243265006627	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
243265006628	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
243265006629	DNA binding site [nucleotide binding]
243265006630	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
243265006631	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
243265006632	DNA binding site [nucleotide binding]
243265006633	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265006634	non-specific DNA binding site [nucleotide binding]; other site
243265006635	salt bridge; other site
243265006636	sequence-specific DNA binding site [nucleotide binding]; other site
243265006637	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
243265006638	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
243265006639	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265006640	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
243265006641	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
243265006642	Toxin YafO, type II toxin-antitoxin system; Region: YafO_toxin; cl08066
243265006643	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265006644	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265006645	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
243265006646	putative catalytic site [active]
243265006647	putative phosphate binding site [ion binding]; other site
243265006648	active site
243265006649	metal binding site A [ion binding]; metal-binding site
243265006650	DNA binding site [nucleotide binding]
243265006651	putative AP binding site [nucleotide binding]; other site
243265006652	putative metal binding site B [ion binding]; other site
243265006653	DNA topoisomerase III; Provisional; Region: PRK07726
243265006654	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
243265006655	active site
243265006656	putative interdomain interaction site [polypeptide binding]; other site
243265006657	putative metal-binding site [ion binding]; other site
243265006658	putative nucleotide binding site [chemical binding]; other site
243265006659	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
243265006660	domain I; other site
243265006661	DNA binding groove [nucleotide binding]
243265006662	phosphate binding site [ion binding]; other site
243265006663	domain II; other site
243265006664	domain III; other site
243265006665	nucleotide binding site [chemical binding]; other site
243265006666	catalytic site [active]
243265006667	domain IV; other site
243265006668	selenophosphate synthetase; Provisional; Region: PRK00943
243265006669	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
243265006670	dimerization interface [polypeptide binding]; other site
243265006671	putative ATP binding site [chemical binding]; other site
243265006672	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
243265006673	putative FMN binding site [chemical binding]; other site
243265006674	protease 4; Provisional; Region: PRK10949
243265006675	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
243265006676	tandem repeat interface [polypeptide binding]; other site
243265006677	oligomer interface [polypeptide binding]; other site
243265006678	active site residues [active]
243265006679	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
243265006680	tandem repeat interface [polypeptide binding]; other site
243265006681	oligomer interface [polypeptide binding]; other site
243265006682	active site residues [active]
243265006683	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
243265006684	active site
243265006685	homodimer interface [polypeptide binding]; other site
243265006686	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
243265006687	Isochorismatase family; Region: Isochorismatase; pfam00857
243265006688	catalytic triad [active]
243265006689	metal binding site [ion binding]; metal-binding site
243265006690	conserved cis-peptide bond; other site
243265006691	Protein of unknown function (DUF1315); Region: DUF1315; pfam07023
243265006692	methionine sulfoxide reductase B; Provisional; Region: PRK00222
243265006693	SelR domain; Region: SelR; pfam01641
243265006694	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
243265006695	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
243265006696	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
243265006697	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
243265006698	alanine racemase; Reviewed; Region: dadX; PRK03646
243265006699	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
243265006700	active site
243265006701	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
243265006702	substrate binding site [chemical binding]; other site
243265006703	catalytic residues [active]
243265006704	dimer interface [polypeptide binding]; other site
243265006705	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
243265006706	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
243265006707	fatty acid metabolism regulator; Provisional; Region: PRK04984
243265006708	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
243265006709	DNA-binding site [nucleotide binding]; DNA binding site
243265006710	FadR C-terminal domain; Region: FadR_C; pfam07840
243265006711	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
243265006712	disulfide bond formation protein B; Provisional; Region: PRK01749
243265006713	Domain of unknown function (DUF333); Region: DUF333; pfam03891
243265006714	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
243265006715	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265006716	Truncated gene. Similar to Unknown Hcp-like protein
243265006717	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
243265006718	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
243265006719	Ligand Binding Site [chemical binding]; other site
243265006720	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
243265006721	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
243265006722	Cl binding site [ion binding]; other site
243265006723	oligomer interface [polypeptide binding]; other site
243265006724	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
243265006725	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
243265006726	peptide binding site [polypeptide binding]; other site
243265006727	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
243265006728	dimer interface [polypeptide binding]; other site
243265006729	catalytic triad [active]
243265006730	peroxidatic and resolving cysteines [active]
243265006731	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
243265006732	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
243265006733	putative aromatic amino acid binding site; other site
243265006734	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
243265006735	putative active site [active]
243265006736	heme pocket [chemical binding]; other site
243265006737	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265006738	Walker A motif; other site
243265006739	ATP binding site [chemical binding]; other site
243265006740	Walker B motif; other site
243265006741	arginine finger; other site
243265006742	hypothetical protein; Provisional; Region: PRK05415
243265006743	Domain of unknown function (DUF697); Region: DUF697; cl12064
243265006744	Predicted ATPase [General function prediction only]; Region: COG3106
243265006745	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
243265006746	phage shock protein C; Region: phageshock_pspC; TIGR02978
243265006747	phage shock protein B; Provisional; Region: pspB; PRK09458
243265006748	phage shock protein PspA; Provisional; Region: PRK10698
243265006749	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
243265006750	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265006751	Walker A motif; other site
243265006752	ATP binding site [chemical binding]; other site
243265006753	Walker B motif; other site
243265006754	arginine finger; other site
243265006755	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
243265006756	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
243265006757	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
243265006758	peptide binding site [polypeptide binding]; other site
243265006759	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
243265006760	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265006761	dimer interface [polypeptide binding]; other site
243265006762	conserved gate region; other site
243265006763	putative PBP binding loops; other site
243265006764	ABC-ATPase subunit interface; other site
243265006765	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
243265006766	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
243265006767	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265006768	dimer interface [polypeptide binding]; other site
243265006769	conserved gate region; other site
243265006770	putative PBP binding loops; other site
243265006771	ABC-ATPase subunit interface; other site
243265006772	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
243265006773	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
243265006774	Walker A/P-loop; other site
243265006775	ATP binding site [chemical binding]; other site
243265006776	Q-loop/lid; other site
243265006777	ABC transporter signature motif; other site
243265006778	Walker B; other site
243265006779	D-loop; other site
243265006780	H-loop/switch region; other site
243265006781	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
243265006782	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
243265006783	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
243265006784	Walker A/P-loop; other site
243265006785	ATP binding site [chemical binding]; other site
243265006786	Q-loop/lid; other site
243265006787	ABC transporter signature motif; other site
243265006788	Walker B; other site
243265006789	D-loop; other site
243265006790	H-loop/switch region; other site
243265006791	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
243265006792	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
243265006793	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
243265006794	NAD binding site [chemical binding]; other site
243265006795	homotetramer interface [polypeptide binding]; other site
243265006796	homodimer interface [polypeptide binding]; other site
243265006797	substrate binding site [chemical binding]; other site
243265006798	active site
243265006799	glutathionine S-transferase; Provisional; Region: PRK10542
243265006800	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
243265006801	C-terminal domain interface [polypeptide binding]; other site
243265006802	GSH binding site (G-site) [chemical binding]; other site
243265006803	dimer interface [polypeptide binding]; other site
243265006804	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
243265006805	dimer interface [polypeptide binding]; other site
243265006806	N-terminal domain interface [polypeptide binding]; other site
243265006807	substrate binding pocket (H-site) [chemical binding]; other site
243265006808	pyridoxamine kinase; Validated; Region: PRK05756
243265006809	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
243265006810	dimer interface [polypeptide binding]; other site
243265006811	pyridoxal binding site [chemical binding]; other site
243265006812	ATP binding site [chemical binding]; other site
243265006813	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
243265006814	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
243265006815	active site
243265006816	HIGH motif; other site
243265006817	dimer interface [polypeptide binding]; other site
243265006818	KMSKS motif; other site
243265006819	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
243265006820	RNA binding surface [nucleotide binding]; other site
243265006821	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
243265006822	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
243265006823	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
243265006824	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
243265006825	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
243265006826	transcriptional regulator SlyA; Provisional; Region: PRK03573
243265006827	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
243265006828	Predicted Fe-S protein [General function prediction only]; Region: COG3313
243265006829	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
243265006830	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
243265006831	dimer interface [polypeptide binding]; other site
243265006832	active site
243265006833	metal binding site [ion binding]; metal-binding site
243265006834	glutathione binding site [chemical binding]; other site
243265006835	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
243265006836	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
243265006837	dimer interface [polypeptide binding]; other site
243265006838	catalytic site [active]
243265006839	putative active site [active]
243265006840	putative substrate binding site [chemical binding]; other site
243265006841	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
243265006842	putative GSH binding site [chemical binding]; other site
243265006843	catalytic residues [active]
243265006844	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
243265006845	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
243265006846	DNA binding site [nucleotide binding]
243265006847	domain linker motif; other site
243265006848	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
243265006849	dimerization interface [polypeptide binding]; other site
243265006850	ligand binding site [chemical binding]; other site
243265006851	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
243265006852	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265006853	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
243265006854	dimerization interface [polypeptide binding]; other site
243265006855	putative transporter; Provisional; Region: PRK11043
243265006856	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265006857	putative substrate translocation pore; other site
243265006858	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
243265006859	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
243265006860	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265006861	S-adenosylmethionine binding site [chemical binding]; other site
243265006862	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
243265006863	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
243265006864	Lumazine binding domain; Region: Lum_binding; pfam00677
243265006865	Lumazine binding domain; Region: Lum_binding; pfam00677
243265006866	multidrug efflux protein; Reviewed; Region: PRK01766
243265006867	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
243265006868	cation binding site [ion binding]; other site
243265006869	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14265
243265006870	pyruvate kinase; Provisional; Region: PRK09206
243265006871	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
243265006872	domain interfaces; other site
243265006873	active site
243265006874	enoyl-CoA hydratase; Provisional; Region: PRK06142
243265006875	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
243265006876	substrate binding site [chemical binding]; other site
243265006877	oxyanion hole (OAH) forming residues; other site
243265006878	trimer interface [polypeptide binding]; other site
243265006879	murein lipoprotein; Provisional; Region: PRK15396
243265006880	L,D-transpeptidase; Provisional; Region: PRK10190
243265006881	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
243265006882	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
243265006883	cysteine desufuration protein SufE; Provisional; Region: PRK09296
243265006884	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
243265006885	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
243265006886	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265006887	catalytic residue [active]
243265006888	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
243265006889	FeS assembly protein SufD; Region: sufD; TIGR01981
243265006890	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
243265006891	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
243265006892	Walker A/P-loop; other site
243265006893	ATP binding site [chemical binding]; other site
243265006894	Q-loop/lid; other site
243265006895	ABC transporter signature motif; other site
243265006896	Walker B; other site
243265006897	D-loop; other site
243265006898	H-loop/switch region; other site
243265006899	putative ABC transporter; Region: ycf24; CHL00085
243265006900	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
243265006901	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
243265006902	Protein of unknown function DUF262; Region: DUF262; pfam03235
243265006903	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
243265006904	CoenzymeA binding site [chemical binding]; other site
243265006905	subunit interaction site [polypeptide binding]; other site
243265006906	PHB binding site; other site
243265006907	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
243265006908	FAD binding domain; Region: FAD_binding_4; pfam01565
243265006909	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
243265006910	putative inner membrane protein; Provisional; Region: PRK10983
243265006911	Domain of unknown function DUF20; Region: UPF0118; pfam01594
243265006912	phosphoenolpyruvate synthase; Validated; Region: PRK06464
243265006913	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
243265006914	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
243265006915	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
243265006916	PEP synthetase regulatory protein; Provisional; Region: PRK05339
243265006917	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
243265006918	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
243265006919	Hemin uptake protein hemP; Region: hemP; pfam10636
243265006920	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
243265006921	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265006922	N-terminal plug; other site
243265006923	ligand-binding site [chemical binding]; other site
243265006924	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
243265006925	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
243265006926	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
243265006927	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
243265006928	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
243265006929	putative hemin binding site; other site
243265006930	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
243265006931	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265006932	ABC-ATPase subunit  interface; other site
243265006933	dimer interface [polypeptide binding]; other site
243265006934	putative PBP binding regions; other site
243265006935	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
243265006936	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
243265006937	Walker A/P-loop; other site
243265006938	ATP binding site [chemical binding]; other site
243265006939	Q-loop/lid; other site
243265006940	ABC transporter signature motif; other site
243265006941	Walker B; other site
243265006942	D-loop; other site
243265006943	H-loop/switch region; other site
243265006944	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
243265006945	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265006946	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265006947	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265006948	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_7; cd08476
243265006949	putative effector binding pocket; other site
243265006950	putative dimerization interface [polypeptide binding]; other site
243265006951	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265006952	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265006953	acyl-activating enzyme (AAE) consensus motif; other site
243265006954	AMP binding site [chemical binding]; other site
243265006955	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265006956	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
243265006957	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
243265006958	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265006959	putative substrate translocation pore; other site
243265006960	N-terminal formyl transferase catalytic core domain of NRPS_like proteins, one of the proteins involved in the synthesis of Oxazolomycin; Region: FMT_core_NRPS_like; cd08649
243265006961	putative active site [active]
243265006962	putative substrate binding site [chemical binding]; other site
243265006963	putative cosubstrate binding site; other site
243265006964	catalytic site [active]
243265006965	C-terminal subdomain of the Formyltransferase-like domain found in OzmH-like proteins; Region: FMT_C_OzmH_like; cd08700
243265006966	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
243265006967	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265006968	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265006969	Outer membrane efflux protein; Region: OEP; pfam02321
243265006970	Outer membrane efflux protein; Region: OEP; pfam02321
243265006971	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
243265006972	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
243265006973	FtsX-like permease family; Region: FtsX; pfam02687
243265006974	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
243265006975	Walker A/P-loop; other site
243265006976	ATP binding site [chemical binding]; other site
243265006977	ABC transporter; Region: ABC_tran; pfam00005
243265006978	Q-loop/lid; other site
243265006979	ABC transporter signature motif; other site
243265006980	Walker B; other site
243265006981	D-loop; other site
243265006982	H-loop/switch region; other site
243265006983	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
243265006984	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
243265006985	NlpC/P60 family; Region: NLPC_P60; pfam00877
243265006986	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
243265006987	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
243265006988	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
243265006989	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
243265006990	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
243265006991	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
243265006992	putative active site [active]
243265006993	putative catalytic site [active]
243265006994	putative Zn binding site [ion binding]; other site
243265006995	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
243265006996	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
243265006997	active site
243265006998	substrate binding site [chemical binding]; other site
243265006999	cosubstrate binding site; other site
243265007000	catalytic site [active]
243265007001	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
243265007002	active site
243265007003	hexamer interface [polypeptide binding]; other site
243265007004	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
243265007005	NAD binding site [chemical binding]; other site
243265007006	substrate binding site [chemical binding]; other site
243265007007	active site
243265007008	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
243265007009	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
243265007010	Ligand binding site; other site
243265007011	Putative Catalytic site; other site
243265007012	DXD motif; other site
243265007013	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
243265007014	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
243265007015	inhibitor-cofactor binding pocket; inhibition site
243265007016	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265007017	catalytic residue [active]
243265007018	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
243265007019	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
243265007020	Walker A/P-loop; other site
243265007021	ATP binding site [chemical binding]; other site
243265007022	Q-loop/lid; other site
243265007023	ABC transporter signature motif; other site
243265007024	Walker B; other site
243265007025	D-loop; other site
243265007026	H-loop/switch region; other site
243265007027	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
243265007028	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265007029	ABC-ATPase subunit  interface; other site
243265007030	dimer interface [polypeptide binding]; other site
243265007031	putative PBP binding regions; other site
243265007032	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
243265007033	IHF dimer interface [polypeptide binding]; other site
243265007034	IHF - DNA interface [nucleotide binding]; other site
243265007035	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
243265007036	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
243265007037	putative tRNA-binding site [nucleotide binding]; other site
243265007038	B3/4 domain; Region: B3_4; pfam03483
243265007039	tRNA synthetase B5 domain; Region: B5; smart00874
243265007040	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
243265007041	dimer interface [polypeptide binding]; other site
243265007042	motif 1; other site
243265007043	motif 3; other site
243265007044	motif 2; other site
243265007045	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
243265007046	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
243265007047	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
243265007048	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
243265007049	dimer interface [polypeptide binding]; other site
243265007050	motif 1; other site
243265007051	active site
243265007052	motif 2; other site
243265007053	motif 3; other site
243265007054	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
243265007055	23S rRNA binding site [nucleotide binding]; other site
243265007056	L21 binding site [polypeptide binding]; other site
243265007057	L13 binding site [polypeptide binding]; other site
243265007058	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
243265007059	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
243265007060	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
243265007061	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
243265007062	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
243265007063	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
243265007064	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
243265007065	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
243265007066	active site
243265007067	dimer interface [polypeptide binding]; other site
243265007068	motif 1; other site
243265007069	motif 2; other site
243265007070	motif 3; other site
243265007071	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
243265007072	anticodon binding site; other site
243265007073	N-terminal formyl transferase catalytic core domain of NRPS_like proteins, one of the proteins involved in the synthesis of Oxazolomycin; Region: FMT_core_NRPS_like; cd08649
243265007074	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
243265007075	putative active site [active]
243265007076	putative substrate binding site [chemical binding]; other site
243265007077	putative cosubstrate binding site; other site
243265007078	catalytic site [active]
243265007079	C-terminal subdomain of the Formyltransferase-like domain found in OzmH-like proteins; Region: FMT_C_OzmH_like; cd08700
243265007080	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265007081	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007082	acyl-activating enzyme (AAE) consensus motif; other site
243265007083	AMP binding site [chemical binding]; other site
243265007084	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007085	Condensation domain; Region: Condensation; pfam00668
243265007086	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Saframycin A gene cluster from Streptomyces lavendulae; Region: A_NRPS_Sfm_like; cd12115
243265007087	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007088	acyl-activating enzyme (AAE) consensus motif; other site
243265007089	AMP binding site [chemical binding]; other site
243265007090	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007091	Condensation domain; Region: Condensation; pfam00668
243265007092	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265007093	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265007094	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265007095	acyl-activating enzyme (AAE) consensus motif; other site
243265007096	AMP binding site [chemical binding]; other site
243265007097	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007098	Condensation domain; Region: Condensation; pfam00668
243265007099	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265007100	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007101	acyl-activating enzyme (AAE) consensus motif; other site
243265007102	AMP binding site [chemical binding]; other site
243265007103	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007104	Condensation domain; Region: Condensation; pfam00668
243265007105	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265007106	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265007107	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265007108	acyl-activating enzyme (AAE) consensus motif; other site
243265007109	AMP binding site [chemical binding]; other site
243265007110	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007111	Condensation domain; Region: Condensation; pfam00668
243265007112	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265007113	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007114	acyl-activating enzyme (AAE) consensus motif; other site
243265007115	AMP binding site [chemical binding]; other site
243265007116	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007117	Condensation domain; Region: Condensation; pfam00668
243265007118	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265007119	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265007120	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265007121	acyl-activating enzyme (AAE) consensus motif; other site
243265007122	AMP binding site [chemical binding]; other site
243265007123	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007124	Condensation domain; Region: Condensation; pfam00668
243265007125	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265007126	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007127	acyl-activating enzyme (AAE) consensus motif; other site
243265007128	AMP binding site [chemical binding]; other site
243265007129	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007130	Condensation domain; Region: Condensation; pfam00668
243265007131	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265007132	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007133	acyl-activating enzyme (AAE) consensus motif; other site
243265007134	AMP binding site [chemical binding]; other site
243265007135	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007136	Condensation domain; Region: Condensation; pfam00668
243265007137	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265007138	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265007139	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265007140	acyl-activating enzyme (AAE) consensus motif; other site
243265007141	AMP binding site [chemical binding]; other site
243265007142	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007143	Condensation domain; Region: Condensation; pfam00668
243265007144	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265007145	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007146	acyl-activating enzyme (AAE) consensus motif; other site
243265007147	AMP binding site [chemical binding]; other site
243265007148	Condensation domain; Region: Condensation; pfam00668
243265007149	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265007150	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265007151	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265007152	acyl-activating enzyme (AAE) consensus motif; other site
243265007153	AMP binding site [chemical binding]; other site
243265007154	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007155	Condensation domain; Region: Condensation; pfam00668
243265007156	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265007157	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007158	acyl-activating enzyme (AAE) consensus motif; other site
243265007159	AMP binding site [chemical binding]; other site
243265007160	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007161	Condensation domain; Region: Condensation; pfam00668
243265007162	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265007163	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265007164	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265007165	acyl-activating enzyme (AAE) consensus motif; other site
243265007166	AMP binding site [chemical binding]; other site
243265007167	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007168	Condensation domain; Region: Condensation; pfam00668
243265007169	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265007170	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265007171	acyl-activating enzyme (AAE) consensus motif; other site
243265007172	AMP binding site [chemical binding]; other site
243265007173	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007174	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
243265007175	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
243265007176	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
243265007177	N-acetyl-D-glucosamine binding site [chemical binding]; other site
243265007178	catalytic residue [active]
243265007179	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
243265007180	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
243265007181	metal binding site [ion binding]; metal-binding site
243265007182	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
243265007183	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
243265007184	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
243265007185	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265007186	ABC-ATPase subunit  interface; other site
243265007187	dimer interface [polypeptide binding]; other site
243265007188	putative PBP binding regions; other site
243265007189	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
243265007190	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265007191	ABC-ATPase subunit  interface; other site
243265007192	dimer interface [polypeptide binding]; other site
243265007193	putative PBP binding regions; other site
243265007194	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
243265007195	Phosphotransferase enzyme family; Region: APH; pfam01636
243265007196	active site
243265007197	ATP binding site [chemical binding]; other site
243265007198	YniB-like protein; Region: YniB; pfam14002
243265007199	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
243265007200	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
243265007201	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265007202	motif II; other site
243265007203	inner membrane protein; Provisional; Region: PRK11648
243265007204	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
243265007205	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
243265007206	heat shock protein HtpX; Provisional; Region: PRK05457
243265007207	carboxy-terminal protease; Provisional; Region: PRK11186
243265007208	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
243265007209	protein binding site [polypeptide binding]; other site
243265007210	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
243265007211	Catalytic dyad [active]
243265007212	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
243265007213	ProP expression regulator; Provisional; Region: PRK04950
243265007214	ProQ/FINO family; Region: ProQ; pfam04352
243265007215	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
243265007216	GAF domain; Region: GAF_2; pfam13185
243265007217	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
243265007218	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
243265007219	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
243265007220	Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only]; Region: CopC; COG2372
243265007221	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
243265007222	Ferritin-like domain; Region: Ferritin; pfam00210
243265007223	ferroxidase diiron center [ion binding]; other site
243265007224	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
243265007225	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
243265007226	hypothetical protein; Provisional; Region: PRK13680
243265007227	hypothetical protein; Provisional; Region: PRK05114
243265007228	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
243265007229	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
243265007230	chorismate binding enzyme; Region: Chorismate_bind; cl10555
243265007231	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
243265007232	putative active site [active]
243265007233	putative CoA binding site [chemical binding]; other site
243265007234	nudix motif; other site
243265007235	metal binding site [ion binding]; metal-binding site
243265007236	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
243265007237	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
243265007238	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
243265007239	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
243265007240	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
243265007241	active pocket/dimerization site; other site
243265007242	active site
243265007243	phosphorylation site [posttranslational modification]
243265007244	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
243265007245	active site
243265007246	phosphorylation site [posttranslational modification]
243265007247	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
243265007248	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
243265007249	hypothetical protein; Provisional; Region: PRK02913
243265007250	Predicted membrane protein [Function unknown]; Region: COG1971
243265007251	Domain of unknown function DUF; Region: DUF204; pfam02659
243265007252	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
243265007253	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265007254	S-adenosylmethionine binding site [chemical binding]; other site
243265007255	Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIR2-like; cd01406
243265007256	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265007257	non-specific DNA binding site [nucleotide binding]; other site
243265007258	sequence-specific DNA binding site [nucleotide binding]; other site
243265007259	salt bridge; other site
243265007260	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265007261	non-specific DNA binding site [nucleotide binding]; other site
243265007262	salt bridge; other site
243265007263	sequence-specific DNA binding site [nucleotide binding]; other site
243265007264	Abortive infection C-terminus; Region: Abi_C; pfam14355
243265007265	Restriction endonuclease XhoI; Region: XhoI; pfam04555
243265007266	Methyltransferase domain; Region: Methyltransf_26; pfam13659
243265007267	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
243265007268	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
243265007269	Truncated gene. Similar to DNA invertase or resolvase
243265007270	GMP synthase; Reviewed; Region: guaA; PRK00074
243265007271	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
243265007272	AMP/PPi binding site [chemical binding]; other site
243265007273	candidate oxyanion hole; other site
243265007274	catalytic triad [active]
243265007275	potential glutamine specificity residues [chemical binding]; other site
243265007276	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
243265007277	ATP Binding subdomain [chemical binding]; other site
243265007278	Ligand Binding sites [chemical binding]; other site
243265007279	Dimerization subdomain; other site
243265007280	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
243265007281	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
243265007282	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
243265007283	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
243265007284	active site
243265007285	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
243265007286	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
243265007287	generic binding surface II; other site
243265007288	generic binding surface I; other site
243265007289	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
243265007290	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
243265007291	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
243265007292	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
243265007293	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
243265007294	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
243265007295	Protein of unknown function, DUF399; Region: DUF399; pfam04187
243265007296	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
243265007297	Malic enzyme, N-terminal domain; Region: malic; pfam00390
243265007298	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
243265007299	putative NAD(P) binding site [chemical binding]; other site
243265007300	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
243265007301	transcriptional regulator NarP; Provisional; Region: PRK10403
243265007302	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265007303	active site
243265007304	phosphorylation site [posttranslational modification]
243265007305	intermolecular recognition site; other site
243265007306	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265007307	DNA binding residues [nucleotide binding]
243265007308	dimerization interface [polypeptide binding]; other site
243265007309	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
243265007310	ArsC family; Region: ArsC; pfam03960
243265007311	putative catalytic residues [active]
243265007312	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
243265007313	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
243265007314	metal binding site [ion binding]; metal-binding site
243265007315	dimer interface [polypeptide binding]; other site
243265007316	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
243265007317	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
243265007318	Uncharacterized protein family (UPF0370); Region: UPF0370; pfam13980
243265007319	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
243265007320	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
243265007321	Helicase; Region: Helicase_RecD; pfam05127
243265007322	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
243265007323	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
243265007324	Predicted membrane protein [Function unknown]; Region: COG2707
243265007325	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
243265007326	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
243265007327	putative NAD(P) binding site [chemical binding]; other site
243265007328	active site
243265007329	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
243265007330	Isochorismatase family; Region: Isochorismatase; pfam00857
243265007331	catalytic triad [active]
243265007332	conserved cis-peptide bond; other site
243265007333	2,3-dihydroxybenzoate-AMP ligase; Region: DHB_AMP_lig; TIGR02275
243265007334	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
243265007335	acyl-activating enzyme (AAE) consensus motif; other site
243265007336	active site
243265007337	AMP binding site [chemical binding]; other site
243265007338	substrate binding site [chemical binding]; other site
243265007339	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265007340	peptide modification radical SAM enzyme, YydG family; Region: rSAM_yydG; TIGR04078
243265007341	FeS/SAM binding site; other site
243265007342	Condensation domain; Region: Condensation; pfam00668
243265007343	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265007344	AMP-binding enzyme; Region: AMP-binding; pfam00501
243265007345	acyl-activating enzyme (AAE) consensus motif; other site
243265007346	active site
243265007347	AMP binding site [chemical binding]; other site
243265007348	CoA binding site [chemical binding]; other site
243265007349	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007350	Condensation domain; Region: Condensation; pfam00668
243265007351	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265007352	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
243265007353	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265007354	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265007355	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
243265007356	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
243265007357	Walker A/P-loop; other site
243265007358	ATP binding site [chemical binding]; other site
243265007359	Q-loop/lid; other site
243265007360	ABC transporter signature motif; other site
243265007361	Walker B; other site
243265007362	D-loop; other site
243265007363	H-loop/switch region; other site
243265007364	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
243265007365	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
243265007366	FtsX-like permease family; Region: FtsX; pfam02687
243265007367	Phosphopantetheine attachment site; Region: PP-binding; cl09936
243265007368	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
243265007369	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
243265007370	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265007371	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265007372	Walker A/P-loop; other site
243265007373	ATP binding site [chemical binding]; other site
243265007374	Q-loop/lid; other site
243265007375	ABC transporter signature motif; other site
243265007376	Walker B; other site
243265007377	D-loop; other site
243265007378	H-loop/switch region; other site
243265007379	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
243265007380	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265007381	Walker A/P-loop; other site
243265007382	ATP binding site [chemical binding]; other site
243265007383	Q-loop/lid; other site
243265007384	ABC transporter signature motif; other site
243265007385	Walker B; other site
243265007386	D-loop; other site
243265007387	H-loop/switch region; other site
243265007388	Homeodomain-like domain; Region: HTH_23; pfam13384
243265007389	Winged helix-turn helix; Region: HTH_29; pfam13551
243265007390	Winged helix-turn helix; Region: HTH_33; pfam13592
243265007391	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265007392	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265007393	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
243265007394	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
243265007395	ATP binding site [chemical binding]; other site
243265007396	active site
243265007397	substrate binding site [chemical binding]; other site
243265007398	lipoprotein; Provisional; Region: PRK11679
243265007399	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
243265007400	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
243265007401	dihydrodipicolinate synthase; Region: dapA; TIGR00674
243265007402	dimer interface [polypeptide binding]; other site
243265007403	active site
243265007404	catalytic residue [active]
243265007405	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
243265007406	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
243265007407	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
243265007408	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
243265007409	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
243265007410	catalytic triad [active]
243265007411	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
243265007412	Domain of unknown function DUF20; Region: UPF0118; pfam01594
243265007413	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
243265007414	Peptidase family M48; Region: Peptidase_M48; pfam01435
243265007415	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
243265007416	TPR motif; other site
243265007417	binding surface
243265007418	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
243265007419	ArsC family; Region: ArsC; pfam03960
243265007420	catalytic residues [active]
243265007421	DNA replication initiation factor; Provisional; Region: PRK08084
243265007422	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
243265007423	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
243265007424	active site
243265007425	P-loop; other site
243265007426	phosphorylation site [posttranslational modification]
243265007427	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
243265007428	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
243265007429	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
243265007430	methionine cluster; other site
243265007431	active site
243265007432	phosphorylation site [posttranslational modification]
243265007433	metal binding site [ion binding]; metal-binding site
243265007434	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
243265007435	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
243265007436	NAD binding site [chemical binding]; other site
243265007437	sugar binding site [chemical binding]; other site
243265007438	divalent metal binding site [ion binding]; other site
243265007439	tetramer (dimer of dimers) interface [polypeptide binding]; other site
243265007440	dimer interface [polypeptide binding]; other site
243265007441	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
243265007442	HicB family; Region: HicB; pfam05534
243265007443	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265007444	active site
243265007445	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
243265007446	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
243265007447	dimerization interface [polypeptide binding]; other site
243265007448	putative ATP binding site [chemical binding]; other site
243265007449	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
243265007450	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
243265007451	active site
243265007452	substrate binding site [chemical binding]; other site
243265007453	cosubstrate binding site; other site
243265007454	catalytic site [active]
243265007455	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
243265007456	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
243265007457	Coenzyme A binding pocket [chemical binding]; other site
243265007458	polyphosphate kinase; Provisional; Region: PRK05443
243265007459	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
243265007460	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
243265007461	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
243265007462	domain interface [polypeptide binding]; other site
243265007463	active site
243265007464	catalytic site [active]
243265007465	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
243265007466	domain interface [polypeptide binding]; other site
243265007467	active site
243265007468	catalytic site [active]
243265007469	exopolyphosphatase; Provisional; Region: PRK10854
243265007470	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
243265007471	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265007472	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_6; cd06154
243265007473	homotrimer interaction site [polypeptide binding]; other site
243265007474	putative active site [active]
243265007475	5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; Region: AroA; COG0128
243265007476	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
243265007477	putative active site [active]
243265007478	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
243265007479	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
243265007480	hinge; other site
243265007481	active site
243265007482	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
243265007483	active site
243265007484	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
243265007485	dimer interface [polypeptide binding]; other site
243265007486	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
243265007487	Ligand Binding Site [chemical binding]; other site
243265007488	Molecular Tunnel; other site
243265007489	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
243265007490	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
243265007491	ligand binding site [chemical binding]; other site
243265007492	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
243265007493	putative switch regulator; other site
243265007494	non-specific DNA interactions [nucleotide binding]; other site
243265007495	DNA binding site [nucleotide binding]
243265007496	sequence specific DNA binding site [nucleotide binding]; other site
243265007497	putative cAMP binding site [chemical binding]; other site
243265007498	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
243265007499	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
243265007500	active site
243265007501	purine riboside binding site [chemical binding]; other site
243265007502	nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans.  Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base; Region: nuc_hydro_CeIAG; cd02649
243265007503	active site
243265007504	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
243265007505	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265007506	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265007507	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
243265007508	Protein export membrane protein; Region: SecD_SecF; cl14618
243265007509	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
243265007510	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
243265007511	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
243265007512	dimerization interface [polypeptide binding]; other site
243265007513	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265007514	dimer interface [polypeptide binding]; other site
243265007515	phosphorylation site [posttranslational modification]
243265007516	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265007517	ATP binding site [chemical binding]; other site
243265007518	Mg2+ binding site [ion binding]; other site
243265007519	G-X-G motif; other site
243265007520	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
243265007521	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265007522	active site
243265007523	phosphorylation site [posttranslational modification]
243265007524	intermolecular recognition site; other site
243265007525	dimerization interface [polypeptide binding]; other site
243265007526	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
243265007527	DNA binding site [nucleotide binding]
243265007528	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
243265007529	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
243265007530	putative protease; Provisional; Region: PRK15452
243265007531	Peptidase family U32; Region: Peptidase_U32; pfam01136
243265007532	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
243265007533	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
243265007534	putative active site; other site
243265007535	catalytic residue [active]
243265007536	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
243265007537	substrate binding site [chemical binding]; other site
243265007538	dimer interface [polypeptide binding]; other site
243265007539	ATP binding site [chemical binding]; other site
243265007540	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
243265007541	DNA-binding site [nucleotide binding]; DNA binding site
243265007542	RNA-binding motif; other site
243265007543	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
243265007544	aromatic amino acid transporter; Provisional; Region: PRK10238
243265007545	MgrB protein; Region: MgrB; pfam13998
243265007546	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
243265007547	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265007548	Predicted small integral membrane protein (DUF2165); Region: DUF2165; pfam09933
243265007549	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
243265007550	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
243265007551	amidase catalytic site [active]
243265007552	Zn binding residues [ion binding]; other site
243265007553	substrate binding site [chemical binding]; other site
243265007554	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
243265007555	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
243265007556	amino acid carrier protein; Region: agcS; TIGR00835
243265007557	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265007558	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265007559	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
243265007560	dimerization interface [polypeptide binding]; other site
243265007561	substrate binding pocket [chemical binding]; other site
243265007562	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
243265007563	GTP cyclohydrolase I; Provisional; Region: PLN03044
243265007564	active site
243265007565	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
243265007566	active site
243265007567	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
243265007568	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
243265007569	tetramer interface [polypeptide binding]; other site
243265007570	TPP-binding site [chemical binding]; other site
243265007571	heterodimer interface [polypeptide binding]; other site
243265007572	phosphorylation loop region [posttranslational modification]
243265007573	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
243265007574	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
243265007575	alpha subunit interface [polypeptide binding]; other site
243265007576	TPP binding site [chemical binding]; other site
243265007577	heterodimer interface [polypeptide binding]; other site
243265007578	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
243265007579	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
243265007580	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
243265007581	E3 interaction surface; other site
243265007582	lipoyl attachment site [posttranslational modification]; other site
243265007583	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
243265007584	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265007585	Condensation domain; Region: Condensation; pfam00668
243265007586	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265007587	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265007588	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
243265007589	TPR motif; other site
243265007590	binding surface
243265007591	Tetratricopeptide repeat; Region: TPR_12; pfam13424
243265007592	pteridine reductase; Provisional; Region: PRK09135
243265007593	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
243265007594	NADP binding site [chemical binding]; other site
243265007595	substrate binding pocket [chemical binding]; other site
243265007596	active site
243265007597	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
243265007598	catalytic center binding site [active]
243265007599	ATP binding site [chemical binding]; other site
243265007600	isocitrate dehydrogenase; Validated; Region: PRK07362
243265007601	isocitrate dehydrogenase; Reviewed; Region: PRK07006
243265007602	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
243265007603	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
243265007604	probable active site [active]
243265007605	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
243265007606	nudix motif; other site
243265007607	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
243265007608	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
243265007609	putative lysogenization regulator; Reviewed; Region: PRK00218
243265007610	adenylosuccinate lyase; Provisional; Region: PRK09285
243265007611	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
243265007612	tetramer interface [polypeptide binding]; other site
243265007613	active site
243265007614	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
243265007615	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265007616	active site
243265007617	phosphorylation site [posttranslational modification]
243265007618	intermolecular recognition site; other site
243265007619	dimerization interface [polypeptide binding]; other site
243265007620	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
243265007621	DNA binding site [nucleotide binding]
243265007622	sensor protein PhoQ; Provisional; Region: PRK10815
243265007623	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
243265007624	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
243265007625	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265007626	dimer interface [polypeptide binding]; other site
243265007627	phosphorylation site [posttranslational modification]
243265007628	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265007629	ATP binding site [chemical binding]; other site
243265007630	Mg2+ binding site [ion binding]; other site
243265007631	G-X-G motif; other site
243265007632	Uncharacterized conserved protein [Function unknown]; Region: COG2850
243265007633	peptidase T; Region: peptidase-T; TIGR01882
243265007634	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
243265007635	metal binding site [ion binding]; metal-binding site
243265007636	dimer interface [polypeptide binding]; other site
243265007637	NAD-dependent deacetylase; Provisional; Region: PRK00481
243265007638	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
243265007639	NAD+ binding site [chemical binding]; other site
243265007640	substrate binding site [chemical binding]; other site
243265007641	Zn binding site [ion binding]; other site
243265007642	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
243265007643	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
243265007644	FtsX-like permease family; Region: FtsX; pfam02687
243265007645	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
243265007646	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
243265007647	Walker A/P-loop; other site
243265007648	ATP binding site [chemical binding]; other site
243265007649	Q-loop/lid; other site
243265007650	ABC transporter signature motif; other site
243265007651	Walker B; other site
243265007652	D-loop; other site
243265007653	H-loop/switch region; other site
243265007654	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
243265007655	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
243265007656	FtsX-like permease family; Region: FtsX; pfam02687
243265007657	transcription-repair coupling factor; Provisional; Region: PRK10689
243265007658	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
243265007659	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265007660	ATP binding site [chemical binding]; other site
243265007661	putative Mg++ binding site [ion binding]; other site
243265007662	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265007663	nucleotide binding region [chemical binding]; other site
243265007664	ATP-binding site [chemical binding]; other site
243265007665	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
243265007666	Pyoverdine/dityrosine biosynthesis protein [Secondary metabolites biosynthesis, transport, and catabolism]; Region: DIT1; COG3207
243265007667	Pyoverdine/dityrosine biosynthesis protein; Region: DIT1_PvcA; pfam05141
243265007668	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
243265007669	Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668
243265007670	substrate binding pocket [chemical binding]; other site
243265007671	active site
243265007672	iron coordination sites [ion binding]; other site
243265007673	Ham1 family; Region: Ham1p_like; pfam01725
243265007674	putative active site [active]
243265007675	Peptidase S8 family domain, uncharacterized subfamily 11; Region: Peptidases_S8_11; cd04843
243265007676	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
243265007677	putative active site [active]
243265007678	putative catalytic triad [active]
243265007679	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
243265007680	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
243265007681	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
243265007682	beta-hexosaminidase; Provisional; Region: PRK05337
243265007683	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
243265007684	thiamine kinase; Region: ycfN_thiK; TIGR02721
243265007685	active site
243265007686	substrate binding site [chemical binding]; other site
243265007687	ATP binding site [chemical binding]; other site
243265007688	uncharacterized proteobacterial lipoprotein; Region: lp_; TIGR02722
243265007689	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
243265007690	nucleotide binding site/active site [active]
243265007691	HIT family signature motif; other site
243265007692	catalytic residue [active]
243265007693	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
243265007694	active site
243265007695	DNA polymerase III subunit delta'; Validated; Region: PRK07993
243265007696	DNA polymerase III subunit delta'; Validated; Region: PRK08485
243265007697	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
243265007698	thymidylate kinase; Validated; Region: tmk; PRK00698
243265007699	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
243265007700	TMP-binding site; other site
243265007701	ATP-binding site [chemical binding]; other site
243265007702	YceG-like family; Region: YceG; pfam02618
243265007703	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
243265007704	dimerization interface [polypeptide binding]; other site
243265007705	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
243265007706	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
243265007707	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265007708	catalytic residue [active]
243265007709	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
243265007710	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
243265007711	dimer interface [polypeptide binding]; other site
243265007712	active site
243265007713	acyl carrier protein; Provisional; Region: acpP; PRK00982
243265007714	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
243265007715	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
243265007716	NAD(P) binding site [chemical binding]; other site
243265007717	homotetramer interface [polypeptide binding]; other site
243265007718	homodimer interface [polypeptide binding]; other site
243265007719	active site
243265007720	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
243265007721	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
243265007722	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
243265007723	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
243265007724	dimer interface [polypeptide binding]; other site
243265007725	active site
243265007726	CoA binding pocket [chemical binding]; other site
243265007727	putative phosphate acyltransferase; Provisional; Region: PRK05331
243265007728	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
243265007729	hypothetical protein; Provisional; Region: PRK11193
243265007730	Maf-like protein; Region: Maf; pfam02545
243265007731	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
243265007732	active site
243265007733	dimer interface [polypeptide binding]; other site
243265007734	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
243265007735	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
243265007736	RNA binding surface [nucleotide binding]; other site
243265007737	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
243265007738	active site
243265007739	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
243265007740	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
243265007741	homodimer interface [polypeptide binding]; other site
243265007742	oligonucleotide binding site [chemical binding]; other site
243265007743	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
243265007744	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
243265007745	NADH(P)-binding; Region: NAD_binding_10; pfam13460
243265007746	NAD(P) binding site [chemical binding]; other site
243265007747	putative active site [active]
243265007748	hypothetical protein; Provisional; Region: PRK05423
243265007749	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
243265007750	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265007751	non-specific DNA binding site [nucleotide binding]; other site
243265007752	salt bridge; other site
243265007753	sequence-specific DNA binding site [nucleotide binding]; other site
243265007754	exonuclease I; Provisional; Region: sbcB; PRK11779
243265007755	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
243265007756	active site
243265007757	catalytic site [active]
243265007758	substrate binding site [chemical binding]; other site
243265007759	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
243265007760	D-lactate dehydrogenase; Provisional; Region: PRK11183
243265007761	FAD binding domain; Region: FAD_binding_4; pfam01565
243265007762	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
243265007763	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
243265007764	putative outer membrane receptor; Provisional; Region: PRK13513
243265007765	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265007766	N-terminal plug; other site
243265007767	ligand-binding site [chemical binding]; other site
243265007768	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
243265007769	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
243265007770	Walker A/P-loop; other site
243265007771	ATP binding site [chemical binding]; other site
243265007772	Q-loop/lid; other site
243265007773	ABC transporter signature motif; other site
243265007774	Walker B; other site
243265007775	D-loop; other site
243265007776	H-loop/switch region; other site
243265007777	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
243265007778	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265007779	ABC-ATPase subunit  interface; other site
243265007780	dimer interface [polypeptide binding]; other site
243265007781	putative PBP binding regions; other site
243265007782	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
243265007783	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
243265007784	putative ligand binding residues [chemical binding]; other site
243265007785	lysine transporter; Provisional; Region: PRK10836
243265007786	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
243265007787	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265007788	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
243265007789	putative dimerization interface [polypeptide binding]; other site
243265007790	Predicted membrane protein [Function unknown]; Region: COG2855
243265007791	endonuclease IV; Provisional; Region: PRK01060
243265007792	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
243265007793	AP (apurinic/apyrimidinic) site pocket; other site
243265007794	DNA interaction; other site
243265007795	Metal-binding active site; metal-binding site
243265007796	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
243265007797	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
243265007798	putative substrate binding site [chemical binding]; other site
243265007799	putative ATP binding site [chemical binding]; other site
243265007800	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_19; cd04678
243265007801	nudix motif; other site
243265007802	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
243265007803	aromatic amino acid transport protein; Region: araaP; TIGR00837
243265007804	elongation factor P; Provisional; Region: PRK04542
243265007805	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
243265007806	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
243265007807	RNA binding site [nucleotide binding]; other site
243265007808	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
243265007809	RNA binding site [nucleotide binding]; other site
243265007810	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
243265007811	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
243265007812	active site
243265007813	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
243265007814	NlpC/P60 family; Region: NLPC_P60; pfam00877
243265007815	hypothetical protein; Provisional; Region: PRK11835
243265007816	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
243265007817	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265007818	putative substrate translocation pore; other site
243265007819	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
243265007820	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
243265007821	RNA binding surface [nucleotide binding]; other site
243265007822	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
243265007823	active site
243265007824	uracil binding [chemical binding]; other site
243265007825	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
243265007826	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265007827	ATP binding site [chemical binding]; other site
243265007828	putative Mg++ binding site [ion binding]; other site
243265007829	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265007830	nucleotide binding region [chemical binding]; other site
243265007831	ATP-binding site [chemical binding]; other site
243265007832	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
243265007833	5S rRNA interface [nucleotide binding]; other site
243265007834	CTC domain interface [polypeptide binding]; other site
243265007835	L16 interface [polypeptide binding]; other site
243265007836	nucleoid-associated protein NdpA; Validated; Region: PRK00378
243265007837	Nucleoid-associated protein [General function prediction only]; Region: COG3081
243265007838	hypothetical protein; Provisional; Region: PRK13689
243265007839	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
243265007840	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
243265007841	Sulfatase; Region: Sulfatase; cl17466
243265007842	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265007843	Phage Tail Collar Domain; Region: Collar; pfam07484
243265007844	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
243265007845	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
243265007846	Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812
243265007847	Hok/gef family; Region: HOK_GEF; pfam01848
243265007848	BRO family, N-terminal domain; Region: Bro-N; smart01040
243265007849	Arc-like DNA binding domain; Region: Arc; pfam03869
243265007850	Phage-related protein [Function unknown]; Region: COG5412
243265007851	Protein of unknown function (DUF2669); Region: DUF2669; pfam10876
243265007852	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
243265007853	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
243265007854	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
243265007855	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834
243265007856	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
243265007857	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
243265007858	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3566
243265007859	Uncharacterized protein, homolog of phage Mu protein gp30 [Function unknown]; Region: COG2369
243265007860	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
243265007861	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
243265007862	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
243265007863	Phage terminase large subunit; Region: Terminase_3; cl12054
243265007864	Terminase-like family; Region: Terminase_6; pfam03237
243265007865	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
243265007866	virion protein; Provisional; Region: V; PHA02564
243265007867	Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106
243265007868	Antitermination protein; Region: Antiterm; pfam03589
243265007869	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
243265007870	Protein of unknown function (DUF2591); Region: DUF2591; pfam10765
243265007871	hypothetical protein; Provisional; Region: PRK09741
243265007872	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
243265007873	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
243265007874	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
243265007875	active site
243265007876	metal binding site [ion binding]; metal-binding site
243265007877	interdomain interaction site; other site
243265007878	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
243265007879	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265007880	ATP binding site [chemical binding]; other site
243265007881	putative Mg++ binding site [ion binding]; other site
243265007882	nucleotide binding region [chemical binding]; other site
243265007883	helicase superfamily c-terminal domain; Region: HELICc; smart00490
243265007884	ATP-binding site [chemical binding]; other site
243265007885	helix_turn_helix, Arsenical Resistance Operon Repressor; Region: HTH_ARSR; smart00418
243265007886	Bacteriophage CII protein; Region: Phage_CII; pfam05269
243265007887	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265007888	non-specific DNA binding site [nucleotide binding]; other site
243265007889	salt bridge; other site
243265007890	sequence-specific DNA binding site [nucleotide binding]; other site
243265007891	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265007892	non-specific DNA binding site [nucleotide binding]; other site
243265007893	salt bridge; other site
243265007894	Predicted transcriptional regulator [Transcription]; Region: COG2932
243265007895	sequence-specific DNA binding site [nucleotide binding]; other site
243265007896	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
243265007897	Catalytic site [active]
243265007898	excinuclease ABC, B subunit; Region: uvrb; TIGR00631
243265007899	RecT family; Region: RecT; pfam03837
243265007900	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
243265007901	Protein of unknown function (DUF1317); Region: DUF1317; pfam07026
243265007902	Protein of unknown function (DUF3268); Region: DUF3268; pfam11672
243265007903	MT-A70; Region: MT-A70; cl01947
243265007904	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
243265007905	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
243265007906	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
243265007907	dimer interface [polypeptide binding]; other site
243265007908	active site
243265007909	Int/Topo IB signature motif; other site
243265007910	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265007911	YcfA-like protein; Region: YcfA; cl00752
243265007912	Prophage antirepressor [Transcription]; Region: COG3617
243265007913	BRO family, N-terminal domain; Region: Bro-N; smart01040
243265007914	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
243265007915	Homeodomain-like domain; Region: HTH_23; pfam13384
243265007916	Winged helix-turn helix; Region: HTH_29; pfam13551
243265007917	Winged helix-turn helix; Region: HTH_33; pfam13592
243265007918	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265007919	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265007920	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
243265007921	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265007922	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265007923	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265007924	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
243265007925	trimer interface [polypeptide binding]; other site
243265007926	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
243265007927	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
243265007928	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
243265007929	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
243265007930	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
243265007931	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
243265007932	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265007933	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265007934	homodimer interface [polypeptide binding]; other site
243265007935	catalytic residue [active]
243265007936	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
243265007937	active site
243265007938	SAM binding site [chemical binding]; other site
243265007939	homodimer interface [polypeptide binding]; other site
243265007940	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
243265007941	ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067
243265007942	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
243265007943	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
243265007944	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
243265007945	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265007946	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
243265007947	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
243265007948	putative dimer interface [polypeptide binding]; other site
243265007949	active site pocket [active]
243265007950	putative cataytic base [active]
243265007951	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
243265007952	catalytic core [active]
243265007953	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
243265007954	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265007955	non-specific DNA binding site [nucleotide binding]; other site
243265007956	salt bridge; other site
243265007957	sequence-specific DNA binding site [nucleotide binding]; other site
243265007958	cobalamin synthase; Reviewed; Region: cobS; PRK00235
243265007959	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
243265007960	homotrimer interface [polypeptide binding]; other site
243265007961	Walker A motif; other site
243265007962	GTP binding site [chemical binding]; other site
243265007963	Walker B motif; other site
243265007964	cobyric acid synthase; Provisional; Region: PRK00784
243265007965	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
243265007966	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
243265007967	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
243265007968	catalytic triad [active]
243265007969	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
243265007970	active site
243265007971	SAM binding site [chemical binding]; other site
243265007972	homodimer interface [polypeptide binding]; other site
243265007973	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
243265007974	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
243265007975	active site
243265007976	C-terminal domain interface [polypeptide binding]; other site
243265007977	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
243265007978	active site
243265007979	N-terminal domain interface [polypeptide binding]; other site
243265007980	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
243265007981	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
243265007982	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
243265007983	active site
243265007984	SAM binding site [chemical binding]; other site
243265007985	homodimer interface [polypeptide binding]; other site
243265007986	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
243265007987	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
243265007988	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
243265007989	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
243265007990	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
243265007991	active site
243265007992	SAM binding site [chemical binding]; other site
243265007993	homodimer interface [polypeptide binding]; other site
243265007994	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
243265007995	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265007996	S-adenosylmethionine binding site [chemical binding]; other site
243265007997	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
243265007998	active site
243265007999	putative homodimer interface [polypeptide binding]; other site
243265008000	SAM binding site [chemical binding]; other site
243265008001	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
243265008002	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
243265008003	Precorrin-8X methylmutase; Region: CbiC; pfam02570
243265008004	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
243265008005	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
243265008006	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
243265008007	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
243265008008	catalytic triad [active]
243265008009	Truncated gene. Some similarities with Unknown protein YnfI precursor of Escherichia coli
243265008010	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
243265008011	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
243265008012	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265008013	non-specific DNA binding site [nucleotide binding]; other site
243265008014	salt bridge; other site
243265008015	sequence-specific DNA binding site [nucleotide binding]; other site
243265008016	Truncated gene. Some similaries with transposase, IS4 family
243265008017	long tail fiber, proximal subunit; Provisional; Region: 34; PHA02584
243265008018	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265008019	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265008020	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
243265008021	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
243265008022	Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219
243265008023	Sulfatase; Region: Sulfatase; pfam00884
243265008024	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265008025	Phage Tail Collar Domain; Region: Collar; pfam07484
243265008026	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
243265008027	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
243265008028	active site
243265008029	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
243265008030	Helix-turn-helix domain; Region: HTH_38; pfam13936
243265008031	Homeodomain-like domain; Region: HTH_32; pfam13565
243265008032	Integrase core domain; Region: rve; pfam00665
243265008033	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
243265008034	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
243265008035	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
243265008036	active site
243265008037	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
243265008038	Uncharacterized protein family (UPF0150); Region: UPF0150; cl00691
243265008039	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265008040	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265008041	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265008042	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265008043	Phage Tail Collar Domain; Region: Collar; pfam07484
243265008044	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
243265008045	Baseplate J-like protein; Region: Baseplate_J; cl01294
243265008046	Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812
243265008047	virion protein; Provisional; Region: V; PHA02564
243265008048	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
243265008049	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
243265008050	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
243265008051	Stress responsive A/B Barrel Domain; Region: Dabb; pfam07876
243265008052	Protein of unknown function (DUF2000); Region: DUF2000; cl02074
243265008053	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
243265008054	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265008055	acyl-activating enzyme (AAE) consensus motif; other site
243265008056	AMP binding site [chemical binding]; other site
243265008057	active site
243265008058	CoA binding site [chemical binding]; other site
243265008059	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
243265008060	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
243265008061	homodimer interface [polypeptide binding]; other site
243265008062	substrate-cofactor binding pocket; other site
243265008063	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265008064	catalytic residue [active]
243265008065	Prephenate dehydratase; Region: PDT; pfam00800
243265008066	Uncharacterized conserved protein [Function unknown]; Region: COG2128
243265008067	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
243265008068	Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423
243265008069	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
243265008070	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
243265008071	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
243265008072	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265008073	ATP binding site [chemical binding]; other site
243265008074	Mg2+ binding site [ion binding]; other site
243265008075	G-X-G motif; other site
243265008076	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
243265008077	putative binding surface; other site
243265008078	active site
243265008079	transcriptional regulator RcsB; Provisional; Region: PRK10840
243265008080	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265008081	active site
243265008082	phosphorylation site [posttranslational modification]
243265008083	intermolecular recognition site; other site
243265008084	dimerization interface [polypeptide binding]; other site
243265008085	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265008086	DNA binding residues [nucleotide binding]
243265008087	dimerization interface [polypeptide binding]; other site
243265008088	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
243265008089	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265008090	dimer interface [polypeptide binding]; other site
243265008091	phosphorylation site [posttranslational modification]
243265008092	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265008093	ATP binding site [chemical binding]; other site
243265008094	Mg2+ binding site [ion binding]; other site
243265008095	G-X-G motif; other site
243265008096	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
243265008097	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265008098	active site
243265008099	phosphorylation site [posttranslational modification]
243265008100	intermolecular recognition site; other site
243265008101	dimerization interface [polypeptide binding]; other site
243265008102	DNA gyrase subunit A; Validated; Region: PRK05560
243265008103	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
243265008104	CAP-like domain; other site
243265008105	active site
243265008106	primary dimer interface [polypeptide binding]; other site
243265008107	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
243265008108	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
243265008109	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
243265008110	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
243265008111	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
243265008112	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
243265008113	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
243265008114	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265008115	S-adenosylmethionine binding site [chemical binding]; other site
243265008116	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
243265008117	ATP cone domain; Region: ATP-cone; pfam03477
243265008118	Class I ribonucleotide reductase; Region: RNR_I; cd01679
243265008119	active site
243265008120	dimer interface [polypeptide binding]; other site
243265008121	catalytic residues [active]
243265008122	effector binding site; other site
243265008123	R2 peptide binding site; other site
243265008124	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
243265008125	dimer interface [polypeptide binding]; other site
243265008126	putative radical transfer pathway; other site
243265008127	diiron center [ion binding]; other site
243265008128	tyrosyl radical; other site
243265008129	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
243265008130	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
243265008131	catalytic loop [active]
243265008132	iron binding site [ion binding]; other site
243265008133	Toxin YafO, type II toxin-antitoxin system; Region: YafO_toxin; pfam13957
243265008134	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
243265008135	oligomeric interface; other site
243265008136	putative active site [active]
243265008137	homodimer interface [polypeptide binding]; other site
243265008138	Plasmid stability protein [General function prediction only]; Region: StbC; COG4691
243265008139	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
243265008140	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
243265008141	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
243265008142	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265008143	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265008144	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265008145	Possible hemagglutinin (DUF637); Region: DUF637; pfam04830
243265008146	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
243265008147	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
243265008148	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
243265008149	tyrosine transporter TyrP; Provisional; Region: PRK15132
243265008150	aromatic amino acid transport protein; Region: araaP; TIGR00837
243265008151	YfaZ precursor; Region: YfaZ; pfam07437
243265008152	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
243265008153	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
243265008154	tetramer interface [polypeptide binding]; other site
243265008155	heme binding pocket [chemical binding]; other site
243265008156	NADPH binding site [chemical binding]; other site
243265008157	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
243265008158	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
243265008159	acyl-activating enzyme (AAE) consensus motif; other site
243265008160	putative AMP binding site [chemical binding]; other site
243265008161	putative active site [active]
243265008162	putative CoA binding site [chemical binding]; other site
243265008163	O-succinylbenzoate synthase; Provisional; Region: PRK05105
243265008164	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
243265008165	active site
243265008166	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
243265008167	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
243265008168	substrate binding site [chemical binding]; other site
243265008169	oxyanion hole (OAH) forming residues; other site
243265008170	trimer interface [polypeptide binding]; other site
243265008171	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
243265008172	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
243265008173	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
243265008174	dimer interface [polypeptide binding]; other site
243265008175	tetramer interface [polypeptide binding]; other site
243265008176	PYR/PP interface [polypeptide binding]; other site
243265008177	TPP binding site [chemical binding]; other site
243265008178	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
243265008179	TPP-binding site; other site
243265008180	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
243265008181	chorismate binding enzyme; Region: Chorismate_bind; cl10555
243265008182	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
243265008183	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
243265008184	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
243265008185	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
243265008186	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
243265008187	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
243265008188	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
243265008189	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
243265008190	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
243265008191	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
243265008192	4Fe-4S binding domain; Region: Fer4; pfam00037
243265008193	4Fe-4S binding domain; Region: Fer4; pfam00037
243265008194	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
243265008195	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
243265008196	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
243265008197	catalytic loop [active]
243265008198	iron binding site [ion binding]; other site
243265008199	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
243265008200	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
243265008201	[4Fe-4S] binding site [ion binding]; other site
243265008202	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
243265008203	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
243265008204	SLBB domain; Region: SLBB; pfam10531
243265008205	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
243265008206	NADH dehydrogenase subunit E; Validated; Region: PRK07539
243265008207	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
243265008208	putative dimer interface [polypeptide binding]; other site
243265008209	[2Fe-2S] cluster binding site [ion binding]; other site
243265008210	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
243265008211	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
243265008212	NADH dehydrogenase subunit D; Validated; Region: PRK06075
243265008213	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
243265008214	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
243265008215	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
243265008216	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265008217	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
243265008218	putative dimerization interface [polypeptide binding]; other site
243265008219	aminotransferase AlaT; Validated; Region: PRK09265
243265008220	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265008221	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265008222	homodimer interface [polypeptide binding]; other site
243265008223	catalytic residue [active]
243265008224	5'-nucleotidase; Provisional; Region: PRK03826
243265008225	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
243265008226	transmembrane helices; other site
243265008227	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
243265008228	TrkA-C domain; Region: TrkA_C; pfam02080
243265008229	TrkA-C domain; Region: TrkA_C; pfam02080
243265008230	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
243265008231	hypothetical protein; Provisional; Region: PRK01816
243265008232	propionate/acetate kinase; Provisional; Region: PRK12379
243265008233	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
243265008234	phosphate acetyltransferase; Reviewed; Region: PRK05632
243265008235	DRTGG domain; Region: DRTGG; pfam07085
243265008236	phosphate acetyltransferase; Region: pta; TIGR00651
243265008237	Homeodomain-like domain; Region: HTH_23; pfam13384
243265008238	Winged helix-turn helix; Region: HTH_29; pfam13551
243265008239	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265008240	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265008241	Methyltransferase domain; Region: Methyltransf_31; pfam13847
243265008242	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265008243	S-adenosylmethionine binding site [chemical binding]; other site
243265008244	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
243265008245	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
243265008246	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265008247	catalytic residue [active]
243265008248	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
243265008249	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
243265008250	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
243265008251	putative active site [active]
243265008252	Zn binding site [ion binding]; other site
243265008253	succinylarginine dihydrolase; Provisional; Region: PRK13281
243265008254	succinylglutamic semialdehyde dehydrogenase; Region: arg_catab_astD; TIGR03240
243265008255	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
243265008256	NAD(P) binding site [chemical binding]; other site
243265008257	catalytic residues [active]
243265008258	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
243265008259	arginine N-succinyltransferase; Region: arg_catab_AstA; TIGR03244
243265008260	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
243265008261	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265008262	inhibitor-cofactor binding pocket; inhibition site
243265008263	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265008264	catalytic residue [active]
243265008265	Transposase; Region: HTH_Tnp_1; cl17663
243265008266	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
243265008267	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265008268	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
243265008269	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265008270	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
243265008271	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
243265008272	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
243265008273	PAAR motif; Region: PAAR_motif; pfam05488
243265008274	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265008275	RHS Repeat; Region: RHS_repeat; cl11982
243265008276	RHS Repeat; Region: RHS_repeat; cl11982
243265008277	RHS Repeat; Region: RHS_repeat; pfam05593
243265008278	RHS Repeat; Region: RHS_repeat; pfam05593
243265008279	RHS Repeat; Region: RHS_repeat; pfam05593
243265008280	RHS Repeat; Region: RHS_repeat; pfam05593
243265008281	RHS Repeat; Region: RHS_repeat; cl11982
243265008282	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265008283	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008284	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008285	acyl-activating enzyme (AAE) consensus motif; other site
243265008286	AMP binding site [chemical binding]; other site
243265008287	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008288	Condensation domain; Region: Condensation; pfam00668
243265008289	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265008290	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008291	acyl-activating enzyme (AAE) consensus motif; other site
243265008292	AMP binding site [chemical binding]; other site
243265008293	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008294	Condensation domain; Region: Condensation; pfam00668
243265008295	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008296	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008297	acyl-activating enzyme (AAE) consensus motif; other site
243265008298	AMP binding site [chemical binding]; other site
243265008299	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008300	Condensation domain; Region: Condensation; pfam00668
243265008301	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265008302	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008303	acyl-activating enzyme (AAE) consensus motif; other site
243265008304	AMP binding site [chemical binding]; other site
243265008305	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008306	Condensation domain; Region: Condensation; pfam00668
243265008307	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008308	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008309	acyl-activating enzyme (AAE) consensus motif; other site
243265008310	AMP binding site [chemical binding]; other site
243265008311	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008312	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
243265008313	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cd02259
243265008314	putative active site [active]
243265008315	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
243265008316	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265008317	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265008318	Walker A/P-loop; other site
243265008319	ATP binding site [chemical binding]; other site
243265008320	Q-loop/lid; other site
243265008321	ABC transporter signature motif; other site
243265008322	Walker B; other site
243265008323	D-loop; other site
243265008324	H-loop/switch region; other site
243265008325	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
243265008326	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265008327	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265008328	A sub-family of peptidase C39 which contains Cyclolysin and Hemolysin processing peptidases.  Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine...; Region: Peptidase_C39_likeA; cd02417
243265008329	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
243265008330	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265008331	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265008332	Walker A/P-loop; other site
243265008333	ATP binding site [chemical binding]; other site
243265008334	Q-loop/lid; other site
243265008335	ABC transporter signature motif; other site
243265008336	Walker B; other site
243265008337	D-loop; other site
243265008338	H-loop/switch region; other site
243265008339	TcdA/TcdB pore forming domain; Region: TcdA_TcdB_pore; pfam12920
243265008340	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008341	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008342	acyl-activating enzyme (AAE) consensus motif; other site
243265008343	AMP binding site [chemical binding]; other site
243265008344	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008345	Condensation domain; Region: Condensation; pfam00668
243265008346	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008347	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008348	acyl-activating enzyme (AAE) consensus motif; other site
243265008349	AMP binding site [chemical binding]; other site
243265008350	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008351	Condensation domain; Region: Condensation; pfam00668
243265008352	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008353	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008354	acyl-activating enzyme (AAE) consensus motif; other site
243265008355	AMP binding site [chemical binding]; other site
243265008356	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008357	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
243265008358	putative transposase; Provisional; Region: PRK09857
243265008359	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265008360	Truncated gene. Some similarities with the C-terminal region of  transposase
243265008361	benzoate transport; Region: 2A0115; TIGR00895
243265008362	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265008363	putative substrate translocation pore; other site
243265008364	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265008365	putative substrate translocation pore; other site
243265008366	acyl-CoA synthetase; Validated; Region: PRK08162
243265008367	Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles and Arabidopsis; Region: ttLC_FACS_AEE21_like; cd12118
243265008368	acyl-activating enzyme (AAE) consensus motif; other site
243265008369	putative active site [active]
243265008370	AMP binding site [chemical binding]; other site
243265008371	putative CoA binding site [chemical binding]; other site
243265008372	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265008373	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265008374	putative substrate translocation pore; other site
243265008375	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
243265008376	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
243265008377	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
243265008378	Citrate synthase; Region: Citrate_synt; pfam00285
243265008379	oxalacetate binding site [chemical binding]; other site
243265008380	citrylCoA binding site [chemical binding]; other site
243265008381	coenzyme A binding site [chemical binding]; other site
243265008382	catalytic triad [active]
243265008383	Homeodomain-like domain; Region: HTH_23; pfam13384
243265008384	Winged helix-turn helix; Region: HTH_29; pfam13551
243265008385	Winged helix-turn helix; Region: HTH_33; pfam13592
243265008386	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265008387	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265008388	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
243265008389	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
243265008390	putative N- and C-terminal domain interface [polypeptide binding]; other site
243265008391	putative active site [active]
243265008392	putative MgATP binding site [chemical binding]; other site
243265008393	catalytic site [active]
243265008394	metal binding site [ion binding]; metal-binding site
243265008395	putative carbohydrate binding site [chemical binding]; other site
243265008396	transcriptional regulator LsrR; Provisional; Region: PRK15418
243265008397	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
243265008398	non-specific DNA interactions [nucleotide binding]; other site
243265008399	DNA binding site [nucleotide binding]
243265008400	sequence specific DNA binding site [nucleotide binding]; other site
243265008401	putative cAMP binding site [chemical binding]; other site
243265008402	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
243265008403	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
243265008404	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
243265008405	Walker A/P-loop; other site
243265008406	ATP binding site [chemical binding]; other site
243265008407	Q-loop/lid; other site
243265008408	ABC transporter signature motif; other site
243265008409	Walker B; other site
243265008410	D-loop; other site
243265008411	H-loop/switch region; other site
243265008412	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
243265008413	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
243265008414	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
243265008415	TM-ABC transporter signature motif; other site
243265008416	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
243265008417	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
243265008418	TM-ABC transporter signature motif; other site
243265008419	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
243265008420	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
243265008421	ligand binding site [chemical binding]; other site
243265008422	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
243265008423	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
243265008424	putative active site; other site
243265008425	catalytic residue [active]
243265008426	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
243265008427	Transposase IS200 like; Region: Y1_Tnp; pfam01797
243265008428	putative toxin YafO; Provisional; Region: PRK09885
243265008429	primosomal protein DnaI; Provisional; Region: PRK02854
243265008430	Truncated gene. Some similarities with transposase
243265008431	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265008432	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
243265008433	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265008434	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
243265008435	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
243265008436	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
243265008437	nudix motif; other site
243265008438	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
243265008439	active site flap/lid [active]
243265008440	nucleophilic elbow; other site
243265008441	catalytic triad [active]
243265008442	Homeodomain-like domain; Region: HTH_23; pfam13384
243265008443	Winged helix-turn helix; Region: HTH_29; pfam13551
243265008444	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265008445	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265008446	Tir chaperone protein (CesT) family; Region: CesT; cl08444
243265008447	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
243265008448	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
243265008449	C-terminal domain interface [polypeptide binding]; other site
243265008450	GSH binding site (G-site) [chemical binding]; other site
243265008451	dimer interface [polypeptide binding]; other site
243265008452	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
243265008453	N-terminal domain interface [polypeptide binding]; other site
243265008454	putative dimer interface [polypeptide binding]; other site
243265008455	active site
243265008456	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
243265008457	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
243265008458	putative NAD(P) binding site [chemical binding]; other site
243265008459	putative active site [active]
243265008460	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
243265008461	Flavoprotein; Region: Flavoprotein; pfam02441
243265008462	amidophosphoribosyltransferase; Provisional; Region: PRK09246
243265008463	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
243265008464	active site
243265008465	tetramer interface [polypeptide binding]; other site
243265008466	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265008467	active site
243265008468	colicin V production protein; Provisional; Region: PRK10845
243265008469	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
243265008470	cell division protein DedD; Provisional; Region: PRK11633
243265008471	Sporulation related domain; Region: SPOR; pfam05036
243265008472	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
243265008473	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
243265008474	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
243265008475	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
243265008476	hypothetical protein; Provisional; Region: PRK10847
243265008477	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
243265008478	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
243265008479	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
243265008480	dimerization interface 3.5A [polypeptide binding]; other site
243265008481	active site
243265008482	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
243265008483	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
243265008484	Pleckstrin homology-like domain; Region: PH-like; cl17171
243265008485	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
243265008486	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
243265008487	ligand binding site [chemical binding]; other site
243265008488	NAD binding site [chemical binding]; other site
243265008489	catalytic site [active]
243265008490	homodimer interface [polypeptide binding]; other site
243265008491	Truncated gene. Similar to insecticidal toxin complex protein TccZ from Photorhabdus luminescens
243265008492	EamA-like transporter family; Region: EamA; pfam00892
243265008493	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
243265008494	EamA-like transporter family; Region: EamA; pfam00892
243265008495	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
243265008496	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265008497	dimer interface [polypeptide binding]; other site
243265008498	phosphorylation site [posttranslational modification]
243265008499	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265008500	ATP binding site [chemical binding]; other site
243265008501	Mg2+ binding site [ion binding]; other site
243265008502	G-X-G motif; other site
243265008503	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
243265008504	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265008505	active site
243265008506	phosphorylation site [posttranslational modification]
243265008507	intermolecular recognition site; other site
243265008508	dimerization interface [polypeptide binding]; other site
243265008509	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
243265008510	DNA binding site [nucleotide binding]
243265008511	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
243265008512	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
243265008513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
243265008514	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
243265008515	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
243265008516	dimer interface [polypeptide binding]; other site
243265008517	active site
243265008518	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
243265008519	Uncharacterized conserved protein [Function unknown]; Region: COG4121
243265008520	YfcL protein; Region: YfcL; pfam08891
243265008521	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
243265008522	hypothetical protein; Provisional; Region: PRK10621
243265008523	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
243265008524	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
243265008525	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
243265008526	Tetramer interface [polypeptide binding]; other site
243265008527	active site
243265008528	FMN-binding site [chemical binding]; other site
243265008529	HemK family putative methylases; Region: hemK_fam; TIGR00536
243265008530	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265008531	S-adenosylmethionine binding site [chemical binding]; other site
243265008532	putative proline-specific permease; Provisional; Region: proY; PRK10580
243265008533	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
243265008534	active sites [active]
243265008535	tetramer interface [polypeptide binding]; other site
243265008536	urocanate hydratase; Provisional; Region: PRK05414
243265008537	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
243265008538	histidine utilization repressor; Provisional; Region: PRK14999
243265008539	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
243265008540	DNA-binding site [nucleotide binding]; DNA binding site
243265008541	UTRA domain; Region: UTRA; pfam07702
243265008542	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
243265008543	putative active site [active]
243265008544	putative metal binding site [ion binding]; other site
243265008545	imidazolonepropionase; Validated; Region: PRK09356
243265008546	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
243265008547	active site
243265008548	hypothetical protein; Provisional; Region: PRK04946
243265008549	Smr domain; Region: Smr; pfam01713
243265008550	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
243265008551	catalytic core [active]
243265008552	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
243265008553	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
243265008554	substrate binding site [chemical binding]; other site
243265008555	oxyanion hole (OAH) forming residues; other site
243265008556	trimer interface [polypeptide binding]; other site
243265008557	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
243265008558	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
243265008559	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
243265008560	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
243265008561	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
243265008562	dimer interface [polypeptide binding]; other site
243265008563	active site
243265008564	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
243265008565	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
243265008566	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
243265008567	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
243265008568	acyl-CoA esterase; Provisional; Region: PRK10673
243265008569	PGAP1-like protein; Region: PGAP1; pfam07819
243265008570	Truncated gene. Highly similar to the C-terminal region of RtxA toxin.
243265008571	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265008572	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265008573	Truncated gene. Highy similar to the N-terminal region of RtxA toxin.
243265008574	Protein of unknown function (DUF2384); Region: DUF2384; cl17718
243265008575	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
243265008576	putative transposase; Provisional; Region: PRK09857
243265008577	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265008578	formamidase; Provisional; Region: amiF; PRK13287
243265008579	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
243265008580	multimer interface [polypeptide binding]; other site
243265008581	active site
243265008582	catalytic triad [active]
243265008583	dimer interface [polypeptide binding]; other site
243265008584	Fic family protein [Function unknown]; Region: COG3177
243265008585	Fic/DOC family; Region: Fic; pfam02661
243265008586	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
243265008587	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
243265008588	Peptidase C80 family; Region: Peptidase_C80; pfam11713
243265008589	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
243265008590	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
243265008591	PAS fold; Region: PAS_4; pfam08448
243265008592	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
243265008593	DNA binding residues [nucleotide binding]
243265008594	PAS fold; Region: PAS_4; pfam08448
243265008595	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265008596	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265008597	DNA binding residues [nucleotide binding]
243265008598	dimerization interface [polypeptide binding]; other site
243265008599	PAS fold; Region: PAS_4; pfam08448
243265008600	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265008601	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265008602	DNA binding residues [nucleotide binding]
243265008603	dimerization interface [polypeptide binding]; other site
243265008604	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
243265008605	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
243265008606	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
243265008607	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
243265008608	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
243265008609	Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994
243265008610	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
243265008611	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
243265008612	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00097
243265008613	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
243265008614	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
243265008615	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
243265008616	PGAP1-like protein; Region: PGAP1; pfam07819
243265008617	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265008618	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265008619	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265008620	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
243265008621	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
243265008622	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
243265008623	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
243265008624	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
243265008625	PAAR motif; Region: PAAR_motif; pfam05488
243265008626	Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994
243265008627	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
243265008628	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
243265008629	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
243265008630	Domain of unknown function (DUF4123); Region: DUF4123; pfam13503
243265008631	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265008632	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265008633	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265008634	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
243265008635	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
243265008636	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00097
243265008637	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
243265008638	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
243265008639	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
243265008640	PGAP1-like protein; Region: PGAP1; pfam07819
243265008641	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265008642	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265008643	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265008644	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
243265008645	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
243265008646	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265008647	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
243265008648	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
243265008649	ligand binding site [chemical binding]; other site
243265008650	Transposase; Region: HTH_Tnp_1; cl17663
243265008651	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
243265008652	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265008653	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
243265008654	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265008655	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
243265008656	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
243265008657	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
243265008658	Truncated gene. Some similarities with Unknown protein
243265008659	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
243265008660	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
243265008661	type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355
243265008662	Protein of unknown function (DUF877); Region: DUF877; pfam05943
243265008663	Protein of unknown function (DUF770); Region: DUF770; pfam05591
243265008664	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117
243265008665	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008666	acyl-activating enzyme (AAE) consensus motif; other site
243265008667	AMP binding site [chemical binding]; other site
243265008668	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008669	Condensation domain; Region: Condensation; pfam00668
243265008670	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008671	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008672	acyl-activating enzyme (AAE) consensus motif; other site
243265008673	AMP binding site [chemical binding]; other site
243265008674	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008675	Condensation domain; Region: Condensation; pfam00668
243265008676	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265008677	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265008678	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008679	acyl-activating enzyme (AAE) consensus motif; other site
243265008680	AMP binding site [chemical binding]; other site
243265008681	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008682	Condensation domain; Region: Condensation; pfam00668
243265008683	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008684	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265008685	acyl-activating enzyme (AAE) consensus motif; other site
243265008686	AMP binding site [chemical binding]; other site
243265008687	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008688	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
243265008689	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265008690	acyl-activating enzyme (AAE) consensus motif; other site
243265008691	AMP binding site [chemical binding]; other site
243265008692	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265008693	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
243265008694	Truncated gene. Highly similar to C-terminal region of alkaline metalloproteinase PrtA precursor
243265008695	Homeodomain-like domain; Region: HTH_23; pfam13384
243265008696	Winged helix-turn helix; Region: HTH_29; pfam13551
243265008697	Winged helix-turn helix; Region: HTH_33; pfam13592
243265008698	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265008699	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265008700	Truncated gene. Similar to the N-terminal region of alkaline metalloproteinase PrtA precursor
243265008701	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
243265008702	Transposase [DNA replication, recombination, and repair]; Region: COG5421
243265008703	Homeodomain-like domain; Region: HTH_23; pfam13384
243265008704	Winged helix-turn helix; Region: HTH_29; pfam13551
243265008705	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265008706	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265008707	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
243265008708	Predicted ATPase [General function prediction only]; Region: COG5293
243265008709	Uncharacterized protein conserved in bacteria (DUF2326); Region: DUF2326; pfam10088
243265008710	SseB protein; Region: SseB; cl06279
243265008711	aminopeptidase B; Provisional; Region: PRK05015
243265008712	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
243265008713	interface (dimer of trimers) [polypeptide binding]; other site
243265008714	Substrate-binding/catalytic site; other site
243265008715	Zn-binding sites [ion binding]; other site
243265008716	hypothetical protein; Provisional; Region: PRK10721
243265008717	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
243265008718	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
243265008719	catalytic loop [active]
243265008720	iron binding site [ion binding]; other site
243265008721	chaperone protein HscA; Provisional; Region: hscA; PRK05183
243265008722	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
243265008723	nucleotide binding site [chemical binding]; other site
243265008724	putative NEF/HSP70 interaction site [polypeptide binding]; other site
243265008725	SBD interface [polypeptide binding]; other site
243265008726	co-chaperone HscB; Provisional; Region: hscB; PRK05014
243265008727	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
243265008728	HSP70 interaction site [polypeptide binding]; other site
243265008729	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
243265008730	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
243265008731	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
243265008732	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
243265008733	trimerization site [polypeptide binding]; other site
243265008734	active site
243265008735	cysteine desulfurase; Provisional; Region: PRK14012
243265008736	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
243265008737	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265008738	catalytic residue [active]
243265008739	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
243265008740	Rrf2 family protein; Region: rrf2_super; TIGR00738
243265008741	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
243265008742	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
243265008743	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
243265008744	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
243265008745	active site
243265008746	dimerization interface [polypeptide binding]; other site
243265008747	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
243265008748	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
243265008749	Ca binding site [ion binding]; other site
243265008750	active site
243265008751	catalytic site [active]
243265008752	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
243265008753	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
243265008754	active site turn [active]
243265008755	phosphorylation site [posttranslational modification]
243265008756	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
243265008757	trehalose operon repressor, proteobacterial; Region: trehalos_R_Ecol; TIGR02405
243265008758	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
243265008759	DNA binding site [nucleotide binding]
243265008760	domain linker motif; other site
243265008761	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
243265008762	dimerization interface [polypeptide binding]; other site
243265008763	ligand binding site [chemical binding]; other site
243265008764	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
243265008765	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265008766	putative substrate translocation pore; other site
243265008767	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
243265008768	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
243265008769	dimer interface [polypeptide binding]; other site
243265008770	active site
243265008771	glycine-pyridoxal phosphate binding site [chemical binding]; other site
243265008772	folate binding site [chemical binding]; other site
243265008773	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
243265008774	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
243265008775	heme-binding site [chemical binding]; other site
243265008776	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
243265008777	FAD binding pocket [chemical binding]; other site
243265008778	FAD binding motif [chemical binding]; other site
243265008779	phosphate binding motif [ion binding]; other site
243265008780	beta-alpha-beta structure motif; other site
243265008781	NAD binding pocket [chemical binding]; other site
243265008782	Heme binding  pocket [chemical binding]; other site
243265008783	recombination regulator RecX; Reviewed; Region: recX; PRK00117
243265008784	multiple promoter invertase; Provisional; Region: mpi; PRK13413
243265008785	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
243265008786	catalytic residues [active]
243265008787	catalytic nucleophile [active]
243265008788	Presynaptic Site I dimer interface [polypeptide binding]; other site
243265008789	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
243265008790	Synaptic Flat tetramer interface [polypeptide binding]; other site
243265008791	Synaptic Site I dimer interface [polypeptide binding]; other site
243265008792	DNA binding site [nucleotide binding]
243265008793	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
243265008794	DNA-binding interface [nucleotide binding]; DNA binding site
243265008795	Domain of unknown function (DUF3846); Region: DUF3846; pfam12957
243265008796	Truncated gene. Some similarities with transposase, IS982 family
243265008797	Homeodomain-like domain; Region: HTH_23; pfam13384
243265008798	Winged helix-turn helix; Region: HTH_29; pfam13551
243265008799	Winged helix-turn helix; Region: HTH_33; pfam13592
243265008800	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265008801	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265008802	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
243265008803	Predicted ATPase [General function prediction only]; Region: COG4637
243265008804	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265008805	ABC transporter signature motif; other site
243265008806	Walker B; other site
243265008807	D-loop; other site
243265008808	H-loop/switch region; other site
243265008809	Truncated gene. Similar to the N-terminal region of VgrG proteins
243265008810	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
243265008811	NAD(P) binding site [chemical binding]; other site
243265008812	catalytic residues [active]
243265008813	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265008814	active site
243265008815	AMP binding site [chemical binding]; other site
243265008816	acyl-activating enzyme (AAE) consensus motif; other site
243265008817	CoA binding site [chemical binding]; other site
243265008818	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265008819	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265008820	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
243265008821	Nitrogen regulatory protein P-II; Region: P-II; smart00938
243265008822	NAD synthetase; Provisional; Region: PRK13981
243265008823	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
243265008824	multimer interface [polypeptide binding]; other site
243265008825	active site
243265008826	catalytic triad [active]
243265008827	protein interface 1 [polypeptide binding]; other site
243265008828	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
243265008829	homodimer interface [polypeptide binding]; other site
243265008830	NAD binding pocket [chemical binding]; other site
243265008831	ATP binding pocket [chemical binding]; other site
243265008832	Mg binding site [ion binding]; other site
243265008833	active-site loop [active]
243265008834	response regulator GlrR; Provisional; Region: PRK15115
243265008835	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265008836	active site
243265008837	phosphorylation site [posttranslational modification]
243265008838	intermolecular recognition site; other site
243265008839	dimerization interface [polypeptide binding]; other site
243265008840	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265008841	Walker A motif; other site
243265008842	ATP binding site [chemical binding]; other site
243265008843	Walker B motif; other site
243265008844	arginine finger; other site
243265008845	hypothetical protein; Provisional; Region: PRK10722
243265008846	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
243265008847	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265008848	dimer interface [polypeptide binding]; other site
243265008849	phosphorylation site [posttranslational modification]
243265008850	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265008851	ATP binding site [chemical binding]; other site
243265008852	Mg2+ binding site [ion binding]; other site
243265008853	G-X-G motif; other site
243265008854	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
243265008855	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
243265008856	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
243265008857	dimerization interface [polypeptide binding]; other site
243265008858	ATP binding site [chemical binding]; other site
243265008859	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
243265008860	dimerization interface [polypeptide binding]; other site
243265008861	ATP binding site [chemical binding]; other site
243265008862	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
243265008863	putative active site [active]
243265008864	catalytic triad [active]
243265008865	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
243265008866	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265008867	substrate binding pocket [chemical binding]; other site
243265008868	membrane-bound complex binding site; other site
243265008869	hinge residues; other site
243265008870	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
243265008871	N-acetyl-D-glucosamine binding site [chemical binding]; other site
243265008872	catalytic residue [active]
243265008873	arginine decarboxylase; Provisional; Region: PRK15029
243265008874	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
243265008875	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
243265008876	homodimer interface [polypeptide binding]; other site
243265008877	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265008878	catalytic residue [active]
243265008879	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
243265008880	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
243265008881	nucleoside/Zn binding site; other site
243265008882	dimer interface [polypeptide binding]; other site
243265008883	catalytic motif [active]
243265008884	Weakly similar to Unknown protein from prophage CP-933H
243265008885	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
243265008886	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265008887	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
243265008888	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
243265008889	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
243265008890	Peptidase C80 family; Region: Peptidase_C80; pfam11713
243265008891	RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2931
243265008892	Phage Tail Collar Domain; Region: Collar; pfam07484
243265008893	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265008894	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265008895	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265008896	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265008897	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265008898	Truncated gene. Some similarities with tail fiber assembly protein from bacteriophage
243265008899	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
243265008900	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
243265008901	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
243265008902	active site
243265008903	hydrophilic channel; other site
243265008904	dimerization interface [polypeptide binding]; other site
243265008905	catalytic residues [active]
243265008906	active site lid [active]
243265008907	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
243265008908	Recombination protein O N terminal; Region: RecO_N; pfam11967
243265008909	Recombination protein O C terminal; Region: RecO_C; pfam02565
243265008910	GTPase Era; Reviewed; Region: era; PRK00089
243265008911	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
243265008912	G1 box; other site
243265008913	GTP/Mg2+ binding site [chemical binding]; other site
243265008914	Switch I region; other site
243265008915	G2 box; other site
243265008916	Switch II region; other site
243265008917	G3 box; other site
243265008918	G4 box; other site
243265008919	G5 box; other site
243265008920	KH domain; Region: KH_2; pfam07650
243265008921	ribonuclease III; Reviewed; Region: rnc; PRK00102
243265008922	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
243265008923	dimerization interface [polypeptide binding]; other site
243265008924	active site
243265008925	metal binding site [ion binding]; metal-binding site
243265008926	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
243265008927	dsRNA binding site [nucleotide binding]; other site
243265008928	signal peptidase I; Provisional; Region: PRK10861
243265008929	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
243265008930	Catalytic site [active]
243265008931	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
243265008932	Catalytic site [active]
243265008933	GTP-binding protein LepA; Provisional; Region: PRK05433
243265008934	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
243265008935	G1 box; other site
243265008936	putative GEF interaction site [polypeptide binding]; other site
243265008937	GTP/Mg2+ binding site [chemical binding]; other site
243265008938	Switch I region; other site
243265008939	G2 box; other site
243265008940	G3 box; other site
243265008941	Switch II region; other site
243265008942	G4 box; other site
243265008943	G5 box; other site
243265008944	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
243265008945	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
243265008946	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
243265008947	SoxR reducing system protein RseC; Provisional; Region: PRK10862
243265008948	anti-sigma E factor; Provisional; Region: rseB; PRK09455
243265008949	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
243265008950	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
243265008951	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
243265008952	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
243265008953	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
243265008954	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265008955	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265008956	DNA binding residues [nucleotide binding]
243265008957	L-aspartate oxidase; Provisional; Region: PRK09077
243265008958	L-aspartate oxidase; Provisional; Region: PRK06175
243265008959	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
243265008960	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
243265008961	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265008962	S-adenosylmethionine binding site [chemical binding]; other site
243265008963	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
243265008964	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
243265008965	ATP binding site [chemical binding]; other site
243265008966	Mg++ binding site [ion binding]; other site
243265008967	motif III; other site
243265008968	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265008969	nucleotide binding region [chemical binding]; other site
243265008970	ATP-binding site [chemical binding]; other site
243265008971	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
243265008972	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265008973	Truncated gene. Some similarities with C-terminal region of ABC transporter
243265008974	Homeodomain-like domain; Region: HTH_23; pfam13384
243265008975	Winged helix-turn helix; Region: HTH_29; pfam13551
243265008976	Winged helix-turn helix; Region: HTH_33; pfam13592
243265008977	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265008978	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265008979	Truncated gene. Some similarities with N-terminal region of ABC transporter
243265008980	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
243265008981	Homeodomain-like domain; Region: HTH_23; pfam13384
243265008982	Winged helix-turn helix; Region: HTH_29; pfam13551
243265008983	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265008984	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265008985	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
243265008986	active site
243265008987	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
243265008988	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
243265008989	active site
243265008990	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
243265008991	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
243265008992	putative ADP-binding pocket [chemical binding]; other site
243265008993	Rhomboid family; Region: Rhomboid; cl11446
243265008994	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
243265008995	FAD binding domain; Region: FAD_binding_4; pfam01565
243265008996	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
243265008997	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
243265008998	active site
243265008999	metal binding site [ion binding]; metal-binding site
243265009000	nudix motif; other site
243265009001	PcrB_like proteins. One member of this family, a protein from Archaeoglobus fulgidus, has been characterized as a (S)-3-O-geranylgeranylglyceryl phosphate synthase (AfGGGPS). AfGGGPS catalyzes the formation of an ether linkage between...; Region: PcrB_like; cd02812
243265009002	substrate binding site [chemical binding]; other site
243265009003	putative active site [active]
243265009004	dimer interface [polypeptide binding]; other site
243265009005	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265009006	FeS/SAM binding site; other site
243265009007	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
243265009008	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
243265009009	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
243265009010	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
243265009011	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
243265009012	ligand binding site [chemical binding]; other site
243265009013	active site
243265009014	UGI interface [polypeptide binding]; other site
243265009015	catalytic site [active]
243265009016	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
243265009017	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
243265009018	dimer interface [polypeptide binding]; other site
243265009019	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
243265009020	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
243265009021	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
243265009022	recombination and repair protein; Provisional; Region: PRK10869
243265009023	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
243265009024	Walker A/P-loop; other site
243265009025	ATP binding site [chemical binding]; other site
243265009026	Q-loop/lid; other site
243265009027	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
243265009028	ABC transporter signature motif; other site
243265009029	Walker B; other site
243265009030	D-loop; other site
243265009031	H-loop/switch region; other site
243265009032	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
243265009033	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
243265009034	hypothetical protein; Validated; Region: PRK01777
243265009035	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
243265009036	putative coenzyme Q binding site [chemical binding]; other site
243265009037	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
243265009038	SmpB-tmRNA interface; other site
243265009039	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
243265009040	non-specific DNA binding site [nucleotide binding]; other site
243265009041	salt bridge; other site
243265009042	sequence-specific DNA binding site [nucleotide binding]; other site
243265009043	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265009044	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265009045	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265009046	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
243265009047	Baseplate J-like protein; Region: Baseplate_J; cl01294
243265009048	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
243265009049	N-acetyl-D-glucosamine binding site [chemical binding]; other site
243265009050	catalytic residue [active]
243265009051	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
243265009052	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
243265009053	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
243265009054	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
243265009055	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
243265009056	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
243265009057	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
243265009058	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
243265009059	Phage terminase large subunit; Region: Terminase_3; cl12054
243265009060	Terminase small subunit; Region: Terminase_2; cl01513
243265009061	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
243265009062	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265009063	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
243265009064	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
243265009065	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
243265009066	catalytic residues [active]
243265009067	hypothetical protein; Provisional; Region: PRK10039
243265009068	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
243265009069	DNA methylase; Region: N6_N4_Mtase; pfam01555
243265009070	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009071	non-specific DNA binding site [nucleotide binding]; other site
243265009072	salt bridge; other site
243265009073	sequence-specific DNA binding site [nucleotide binding]; other site
243265009074	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009075	non-specific DNA binding site [nucleotide binding]; other site
243265009076	salt bridge; other site
243265009077	sequence-specific DNA binding site [nucleotide binding]; other site
243265009078	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265009079	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265009080	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
243265009081	Baseplate J-like protein; Region: Baseplate_J; cl01294
243265009082	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
243265009083	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
243265009084	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
243265009085	Phage protein D [General function prediction only]; Region: COG3500
243265009086	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
243265009087	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
243265009088	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
243265009089	Phage tail tube protein FII; Region: Phage_tube; cl01390
243265009090	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
243265009091	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
243265009092	Gp37 protein; Region: Gp37; pfam09646
243265009093	Protein of unknown function (DUF1320); Region: DUF1320; pfam07030
243265009094	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
243265009095	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
243265009096	Protein of unknown function (DUF935); Region: DUF935; pfam06074
243265009097	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
243265009098	Protein of unknown function (DUF3486); Region: DUF3486; pfam11985
243265009099	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
243265009100	N-acetyl-D-glucosamine binding site [chemical binding]; other site
243265009101	catalytic residue [active]
243265009102	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
243265009103	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
243265009104	Peptidase M50B-like; Region: Peptidase_M50B; pfam13398
243265009105	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009106	sequence-specific DNA binding site [nucleotide binding]; other site
243265009107	salt bridge; other site
243265009108	phage-associated protein, BcepMu gp16 family; Region: BcepMu_gp16; TIGR04111
243265009109	IclR helix-turn-helix domain; Region: HTH_IclR; pfam09339
243265009110	Integrase core domain; Region: rve; pfam00665
243265009111	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
243265009112	AAA domain; Region: AAA_22; pfam13401
243265009113	Walker A motif; other site
243265009114	ATP binding site [chemical binding]; other site
243265009115	Walker B motif; other site
243265009116	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
243265009117	Mor transcription activator family; Region: Mor; pfam08765
243265009118	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
243265009119	DNA methylase; Region: N6_N4_Mtase; pfam01555
243265009120	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
243265009121	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
243265009122	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
243265009123	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009124	non-specific DNA binding site [nucleotide binding]; other site
243265009125	salt bridge; other site
243265009126	sequence-specific DNA binding site [nucleotide binding]; other site
243265009127	Predicted Zn peptidase [Amino acid transport and metabolism]; Region: COG2856
243265009128	replicative DNA helicase; Region: DnaB; TIGR00665
243265009129	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
243265009130	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
243265009131	Walker A motif; other site
243265009132	ATP binding site [chemical binding]; other site
243265009133	Walker B motif; other site
243265009134	DNA binding loops [nucleotide binding]
243265009135	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
243265009136	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265009137	Walker A motif; other site
243265009138	ATP binding site [chemical binding]; other site
243265009139	Walker B motif; other site
243265009140	Helix-turn-helix domain; Region: HTH_36; pfam13730
243265009141	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
243265009142	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
243265009143	transcriptional repressor DicA; Reviewed; Region: PRK09706
243265009144	Homeodomain-like domain; Region: HTH_23; pfam13384
243265009145	Winged helix-turn helix; Region: HTH_29; pfam13551
243265009146	Winged helix-turn helix; Region: HTH_33; pfam13592
243265009147	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265009148	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265009149	Siphovirus Gp157; Region: Sipho_Gp157; pfam05565
243265009150	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
243265009151	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
243265009152	Int/Topo IB signature motif; other site
243265009153	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265009154	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
243265009155	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
243265009156	sequence-specific DNA binding site [nucleotide binding]; other site
243265009157	salt bridge; other site
243265009158	YcfA-like protein; Region: YcfA; pfam07927
243265009159	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265009160	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265009161	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
243265009162	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
243265009163	DNA binding residues [nucleotide binding]
243265009164	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
243265009165	Protein of unknown function (DUF2938); Region: DUF2938; pfam11158
243265009166	Protein of unknown function (DUF1375); Region: DUF1375; cl11456
243265009167	Fic/DOC family; Region: Fic; cl00960
243265009168	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
243265009169	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
243265009170	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
243265009171	Fimbrial protein; Region: Fimbrial; cl01416
243265009172	FaeA-like protein; Region: FaeA; pfam04703
243265009173	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265009174	Coenzyme A binding pocket [chemical binding]; other site
243265009175	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
243265009176	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
243265009177	active site
243265009178	catalytic triad [active]
243265009179	oxyanion hole [active]
243265009180	Autotransporter beta-domain; Region: Autotransporter; cl17461
243265009181	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
243265009182	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
243265009183	Coenzyme A binding pocket [chemical binding]; other site
243265009184	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
243265009185	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
243265009186	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
243265009187	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
243265009188	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
243265009189	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
243265009190	Tetratricopeptide repeat; Region: TPR_16; pfam13432
243265009191	binding surface
243265009192	TPR motif; other site
243265009193	Protein of unknown function (DUF560); Region: DUF560; pfam04575
243265009194	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
243265009195	multidrug efflux protein; Reviewed; Region: PRK01766
243265009196	cation binding site [ion binding]; other site
243265009197	O-acetylhomoserine aminocarboxypropyltransferase; Validated; Region: PRK06084
243265009198	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
243265009199	homodimer interface [polypeptide binding]; other site
243265009200	substrate-cofactor binding pocket; other site
243265009201	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265009202	catalytic residue [active]
243265009203	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cd00413
243265009204	active site
243265009205	catalytic residues [active]
243265009206	TonB-dependent copper receptor; Region: TonB-copper; TIGR01778
243265009207	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265009208	N-terminal plug; other site
243265009209	ligand-binding site [chemical binding]; other site
243265009210	Protein of unknown function (DUF2946); Region: DUF2946; pfam11162
243265009211	Predicted ATPase [General function prediction only]; Region: COG5293
243265009212	Uncharacterized protein conserved in bacteria (DUF2326); Region: DUF2326; pfam10088
243265009213	Cupin-like domain; Region: Cupin_8; pfam13621
243265009214	Penicillin amidase; Region: Penicil_amidase; pfam01804
243265009215	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
243265009216	Cephalosporin acylase (CA) belongs to a family of beta-lactam acylases that includes penicillin G acylase (PGA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_CA; cd01936
243265009217	active site
243265009218	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
243265009219	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
243265009220	substrate binding pocket [chemical binding]; other site
243265009221	active site
243265009222	iron coordination sites [ion binding]; other site
243265009223	Aspartyl/Asparaginyl beta-hydroxylase; Region: Asp_Arg_Hydrox; cl17820
243265009224	ABC-type siderophore export system, fused ATPase and permease components [Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism]; Region: PvdE; COG4615
243265009225	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265009226	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265009227	Walker A/P-loop; other site
243265009228	ATP binding site [chemical binding]; other site
243265009229	Q-loop/lid; other site
243265009230	ABC transporter signature motif; other site
243265009231	Walker B; other site
243265009232	D-loop; other site
243265009233	H-loop/switch region; other site
243265009234	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
243265009235	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265009236	S-adenosylmethionine binding site [chemical binding]; other site
243265009237	Condensation domain; Region: Condensation; pfam00668
243265009238	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265009239	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265009240	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265009241	acyl-activating enzyme (AAE) consensus motif; other site
243265009242	AMP binding site [chemical binding]; other site
243265009243	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009244	Condensation domain; Region: Condensation; pfam00668
243265009245	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265009246	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265009247	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265009248	acyl-activating enzyme (AAE) consensus motif; other site
243265009249	AMP binding site [chemical binding]; other site
243265009250	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009251	Condensation domain; Region: Condensation; pfam00668
243265009252	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265009253	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265009254	acyl-activating enzyme (AAE) consensus motif; other site
243265009255	AMP binding site [chemical binding]; other site
243265009256	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009257	Condensation domain; Region: Condensation; pfam00668
243265009258	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265009259	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265009260	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265009261	acyl-activating enzyme (AAE) consensus motif; other site
243265009262	AMP binding site [chemical binding]; other site
243265009263	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009264	Condensation domain; Region: Condensation; pfam00668
243265009265	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265009266	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265009267	The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116
243265009268	acyl-activating enzyme (AAE) consensus motif; other site
243265009269	AMP binding site [chemical binding]; other site
243265009270	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009271	Condensation domain; Region: Condensation; pfam00668
243265009272	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265009273	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265009274	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265009275	acyl-activating enzyme (AAE) consensus motif; other site
243265009276	AMP binding site [chemical binding]; other site
243265009277	Condensation domain; Region: Condensation; pfam00668
243265009278	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265009279	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265009280	acyl-activating enzyme (AAE) consensus motif; other site
243265009281	AMP binding site [chemical binding]; other site
243265009282	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009283	Condensation domain; Region: Condensation; pfam00668
243265009284	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265009285	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265009286	acyl-activating enzyme (AAE) consensus motif; other site
243265009287	AMP binding site [chemical binding]; other site
243265009288	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009289	Condensation domain; Region: Condensation; pfam00668
243265009290	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
243265009291	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
243265009292	acyl-activating enzyme (AAE) consensus motif; other site
243265009293	AMP binding site [chemical binding]; other site
243265009294	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009295	Condensation domain; Region: Condensation; pfam00668
243265009296	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265009297	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265009298	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265009299	acyl-activating enzyme (AAE) consensus motif; other site
243265009300	AMP binding site [chemical binding]; other site
243265009301	active site
243265009302	CoA binding site [chemical binding]; other site
243265009303	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265009304	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265009305	Coenzyme A binding pocket [chemical binding]; other site
243265009306	Cupin-like domain; Region: Cupin_8; pfam13621
243265009307	diaminobutyrate--2-oxoglutarate aminotransferase; Region: ectoine_ectB; TIGR02407
243265009308	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265009309	inhibitor-cofactor binding pocket; inhibition site
243265009310	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265009311	catalytic residue [active]
243265009312	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
243265009313	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265009314	acyl-activating enzyme (AAE) consensus motif; other site
243265009315	AMP binding site [chemical binding]; other site
243265009316	active site
243265009317	CoA binding site [chemical binding]; other site
243265009318	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
243265009319	2-methylcitrate dehydratase; Region: prpD; TIGR02330
243265009320	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
243265009321	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
243265009322	dimer interface [polypeptide binding]; other site
243265009323	active site
243265009324	citrylCoA binding site [chemical binding]; other site
243265009325	oxalacetate/citrate binding site [chemical binding]; other site
243265009326	coenzyme A binding site [chemical binding]; other site
243265009327	catalytic triad [active]
243265009328	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
243265009329	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
243265009330	tetramer interface [polypeptide binding]; other site
243265009331	active site
243265009332	Mg2+/Mn2+ binding site [ion binding]; other site
243265009333	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
243265009334	Propionate catabolism activator; Region: PrpR_N; pfam06506
243265009335	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265009336	Walker A motif; other site
243265009337	ATP binding site [chemical binding]; other site
243265009338	Walker B motif; other site
243265009339	arginine finger; other site
243265009340	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
243265009341	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
243265009342	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
243265009343	conserved cys residue [active]
243265009344	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
243265009345	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
243265009346	conserved cys residue [active]
243265009347	putative transposase; Provisional; Region: PRK09857
243265009348	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265009349	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
243265009350	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
243265009351	trimer interface [polypeptide binding]; other site
243265009352	active site
243265009353	substrate binding site [chemical binding]; other site
243265009354	CoA binding site [chemical binding]; other site
243265009355	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
243265009356	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
243265009357	dimer interface [polypeptide binding]; other site
243265009358	putative anticodon binding site; other site
243265009359	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
243265009360	motif 1; other site
243265009361	active site
243265009362	motif 2; other site
243265009363	motif 3; other site
243265009364	This domain is found in peptide chain release factors; Region: PCRF; smart00937
243265009365	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
243265009366	RF-1 domain; Region: RF-1; pfam00472
243265009367	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
243265009368	DHH family; Region: DHH; pfam01368
243265009369	DHHA1 domain; Region: DHHA1; pfam02272
243265009370	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
243265009371	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
243265009372	dimerization domain [polypeptide binding]; other site
243265009373	dimer interface [polypeptide binding]; other site
243265009374	catalytic residues [active]
243265009375	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
243265009376	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265009377	active site
243265009378	Int/Topo IB signature motif; other site
243265009379	flavodoxin FldB; Provisional; Region: PRK12359
243265009380	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
243265009381	hypothetical protein; Provisional; Region: PRK10878
243265009382	putative global regulator; Reviewed; Region: PRK09559
243265009383	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
243265009384	HD domain; Region: HD_3; pfam13023
243265009385	Truncated gene. Some similarities with  proton antiporter efflux pump of Photorhabdus
243265009386	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
243265009387	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265009388	putative substrate translocation pore; other site
243265009389	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
243265009390	prephenate dehydrogenase; Validated; Region: PRK08507
243265009391	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
243265009392	Glutamine amidotransferase class-I; Region: GATase; pfam00117
243265009393	glutamine binding [chemical binding]; other site
243265009394	catalytic triad [active]
243265009395	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
243265009396	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
243265009397	chorismate binding enzyme; Region: Chorismate_bind; cl10555
243265009398	Chorismate mutase type II; Region: CM_2; smart00830
243265009399	hypothetical protein; Provisional; Region: PRK07505
243265009400	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
243265009401	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265009402	catalytic residue [active]
243265009403	Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890
243265009404	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265009405	S-adenosylmethionine binding site [chemical binding]; other site
243265009406	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
243265009407	Homeodomain-like domain; Region: HTH_23; pfam13384
243265009408	Winged helix-turn helix; Region: HTH_29; pfam13551
243265009409	Winged helix-turn helix; Region: HTH_33; pfam13592
243265009410	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265009411	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265009412	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
243265009413	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
243265009414	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
243265009415	Truncated gene. Some similarities with Unknown protein of Photorhabdus
243265009416	Truncated gene. Some similarities with Unknown protein of Photorhabdus
243265009417	Domain of unknown function (DUF4279); Region: DUF4279; pfam14106
243265009418	Truncated gene. Some similarities wioth MafB-related protein
243265009419	Possible hemagglutinin (DUF637); Region: DUF637; pfam04830
243265009420	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265009421	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265009422	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265009423	active site
243265009424	Int/Topo IB signature motif; other site
243265009425	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265009426	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265009427	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265009428	active site
243265009429	metal binding site [ion binding]; metal-binding site
243265009430	interdomain interaction site; other site
243265009431	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265009432	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009433	non-specific DNA binding site [nucleotide binding]; other site
243265009434	salt bridge; other site
243265009435	sequence-specific DNA binding site [nucleotide binding]; other site
243265009436	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265009437	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265009438	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265009439	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265009440	active site
243265009441	Int/Topo IB signature motif; other site
243265009442	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265009443	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265009444	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265009445	active site
243265009446	metal binding site [ion binding]; metal-binding site
243265009447	interdomain interaction site; other site
243265009448	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265009449	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009450	non-specific DNA binding site [nucleotide binding]; other site
243265009451	salt bridge; other site
243265009452	sequence-specific DNA binding site [nucleotide binding]; other site
243265009453	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265009454	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265009455	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265009456	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265009457	Truncated gene. Some similarities with hemolysin secretion/activation protein
243265009458	glycine dehydrogenase; Provisional; Region: PRK05367
243265009459	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
243265009460	tetramer interface [polypeptide binding]; other site
243265009461	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265009462	catalytic residue [active]
243265009463	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
243265009464	tetramer interface [polypeptide binding]; other site
243265009465	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265009466	catalytic residue [active]
243265009467	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
243265009468	lipoyl attachment site [posttranslational modification]; other site
243265009469	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
243265009470	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
243265009471	oxidoreductase; Provisional; Region: PRK08013
243265009472	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
243265009473	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
243265009474	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
243265009475	proline aminopeptidase P II; Provisional; Region: PRK10879
243265009476	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
243265009477	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
243265009478	active site
243265009479	hypothetical protein; Reviewed; Region: PRK01736
243265009480	Z-ring-associated protein; Provisional; Region: PRK10972
243265009481	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
243265009482	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
243265009483	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
243265009484	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
243265009485	ligand binding site [chemical binding]; other site
243265009486	NAD binding site [chemical binding]; other site
243265009487	tetramer interface [polypeptide binding]; other site
243265009488	catalytic site [active]
243265009489	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
243265009490	L-serine binding site [chemical binding]; other site
243265009491	ACT domain interface; other site
243265009492	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
243265009493	tetramer (dimer of dimers) interface [polypeptide binding]; other site
243265009494	active site
243265009495	dimer interface [polypeptide binding]; other site
243265009496	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
243265009497	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265009498	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
243265009499	putative dimerization interface [polypeptide binding]; other site
243265009500	Uncharacterized conserved protein [Function unknown]; Region: COG2968
243265009501	oxidative stress defense protein; Provisional; Region: PRK11087
243265009502	arginine exporter protein; Provisional; Region: PRK09304
243265009503	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
243265009504	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265009505	FeS/SAM binding site; other site
243265009506	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
243265009507	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
243265009508	mechanosensitive channel MscS; Provisional; Region: PRK10334
243265009509	Mechanosensitive ion channel; Region: MS_channel; pfam00924
243265009510	hypothetical protein; Provisional; Region: PRK05248
243265009511	Stress responsive A/B Barrel Domain; Region: Dabb; cl17744
243265009512	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
243265009513	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
243265009514	substrate binding site [chemical binding]; other site
243265009515	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
243265009516	substrate binding site [chemical binding]; other site
243265009517	ligand binding site [chemical binding]; other site
243265009518	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
243265009519	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265009520	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
243265009521	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
243265009522	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
243265009523	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
243265009524	E3 interaction surface; other site
243265009525	lipoyl attachment site [posttranslational modification]; other site
243265009526	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
243265009527	E3 interaction surface; other site
243265009528	lipoyl attachment site [posttranslational modification]; other site
243265009529	e3 binding domain; Region: E3_binding; pfam02817
243265009530	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
243265009531	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
243265009532	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
243265009533	dimer interface [polypeptide binding]; other site
243265009534	TPP-binding site [chemical binding]; other site
243265009535	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
243265009536	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
243265009537	DNA-binding site [nucleotide binding]; DNA binding site
243265009538	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
243265009539	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009540	non-specific DNA binding site [nucleotide binding]; other site
243265009541	salt bridge; other site
243265009542	sequence-specific DNA binding site [nucleotide binding]; other site
243265009543	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
243265009544	Fimbrial protein; Region: Fimbrial; cl01416
243265009545	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
243265009546	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
243265009547	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
243265009550	Similar to the N-terminal region of outer membrane usher protein precursor
243265009551	Some high similarities with Unknown protein of Photorhabdus
243265009552	regulatory protein AmpE; Provisional; Region: PRK10987
243265009553	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
243265009554	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
243265009555	dimerization interface [polypeptide binding]; other site
243265009556	active site
243265009557	putative major pilin subunit; Provisional; Region: PRK10574
243265009558	hypothetical protein; Provisional; Region: PRK10436
243265009559	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
243265009560	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
243265009561	Walker A motif; other site
243265009562	ATP binding site [chemical binding]; other site
243265009563	Walker B motif; other site
243265009564	type IV pilin biogenesis protein; Provisional; Region: PRK10573
243265009565	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
243265009566	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
243265009567	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
243265009568	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
243265009569	CoA-binding site [chemical binding]; other site
243265009570	ATP-binding [chemical binding]; other site
243265009571	hypothetical protein; Provisional; Region: PRK05287
243265009572	DNA gyrase inhibitor; Reviewed; Region: PRK00418
243265009573	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
243265009574	active site
243265009575	8-oxo-dGMP binding site [chemical binding]; other site
243265009576	nudix motif; other site
243265009577	metal binding site [ion binding]; metal-binding site
243265009578	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
243265009579	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
243265009580	SEC-C motif; Region: SEC-C; pfam02810
243265009581	SecA regulator SecM; Provisional; Region: PRK02943
243265009582	Protein of unknown function (DUF721); Region: DUF721; cl02324
243265009583	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
243265009584	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
243265009585	cell division protein FtsZ; Validated; Region: PRK09330
243265009586	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
243265009587	nucleotide binding site [chemical binding]; other site
243265009588	SulA interaction site; other site
243265009589	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
243265009590	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
243265009591	Cell division protein FtsA; Region: FtsA; pfam14450
243265009592	cell division protein FtsQ; Provisional; Region: PRK10775
243265009593	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
243265009594	Cell division protein FtsQ; Region: FtsQ; pfam03799
243265009595	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
243265009596	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
243265009597	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
243265009598	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
243265009599	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
243265009600	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
243265009601	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
243265009602	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
243265009603	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
243265009604	active site
243265009605	homodimer interface [polypeptide binding]; other site
243265009606	cell division protein FtsW; Provisional; Region: PRK10774
243265009607	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
243265009608	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
243265009609	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
243265009610	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
243265009611	Mg++ binding site [ion binding]; other site
243265009612	putative catalytic motif [active]
243265009613	putative substrate binding site [chemical binding]; other site
243265009614	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
243265009615	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
243265009616	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
243265009617	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
243265009618	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
243265009619	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
243265009620	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
243265009621	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
243265009622	Domain of unknown function (DUF1704); Region: DUF1704; cl06858
243265009623	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
243265009624	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
243265009625	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
243265009626	cell division protein FtsL; Provisional; Region: PRK10772
243265009627	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
243265009628	MraW methylase family; Region: Methyltransf_5; pfam01795
243265009629	cell division protein MraZ; Reviewed; Region: PRK00326
243265009630	MraZ protein; Region: MraZ; pfam02381
243265009631	MraZ protein; Region: MraZ; pfam02381
243265009632	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
243265009633	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
243265009634	DNA binding site [nucleotide binding]
243265009635	domain linker motif; other site
243265009636	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
243265009637	dimerization interface [polypeptide binding]; other site
243265009638	ligand binding site [chemical binding]; other site
243265009639	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
243265009640	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
243265009641	putative valine binding site [chemical binding]; other site
243265009642	dimer interface [polypeptide binding]; other site
243265009643	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
243265009644	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
243265009645	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
243265009646	PYR/PP interface [polypeptide binding]; other site
243265009647	dimer interface [polypeptide binding]; other site
243265009648	TPP binding site [chemical binding]; other site
243265009649	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
243265009650	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
243265009651	TPP-binding site [chemical binding]; other site
243265009652	dimer interface [polypeptide binding]; other site
243265009653	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
243265009654	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
243265009655	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
243265009656	binding surface
243265009657	Sel1-like repeats; Region: SEL1; smart00671
243265009658	Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545
243265009659	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
243265009660	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
243265009661	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
243265009662	acyl-activating enzyme (AAE) consensus motif; other site
243265009663	putative AMP binding site [chemical binding]; other site
243265009664	putative active site [active]
243265009665	putative CoA binding site [chemical binding]; other site
243265009666	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
243265009667	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265009668	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
243265009669	putative substrate binding pocket [chemical binding]; other site
243265009670	putative dimerization interface [polypeptide binding]; other site
243265009671	2-isopropylmalate synthase; Validated; Region: PRK00915
243265009672	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
243265009673	active site
243265009674	catalytic residues [active]
243265009675	metal binding site [ion binding]; metal-binding site
243265009676	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
243265009677	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
243265009678	tartrate dehydrogenase; Region: TTC; TIGR02089
243265009679	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
243265009680	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
243265009681	substrate binding site [chemical binding]; other site
243265009682	ligand binding site [chemical binding]; other site
243265009683	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
243265009684	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
243265009685	substrate binding site [chemical binding]; other site
243265009686	transcriptional regulator SgrR; Provisional; Region: PRK13626
243265009687	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
243265009688	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
243265009689	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
243265009690	putative DNA-binding cleft [nucleotide binding]; other site
243265009691	putative DNA clevage site; other site
243265009692	molecular lever; other site
243265009693	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
243265009694	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
243265009695	agmatinase; Region: agmatinase; TIGR01230
243265009696	oligomer interface [polypeptide binding]; other site
243265009697	putative active site [active]
243265009698	Mn binding site [ion binding]; other site
243265009699	arginine decarboxylase; Provisional; Region: PRK05354
243265009700	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
243265009701	dimer interface [polypeptide binding]; other site
243265009702	active site
243265009703	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
243265009704	catalytic residues [active]
243265009705	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
243265009706	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
243265009707	S-adenosylmethionine synthetase; Validated; Region: PRK05250
243265009708	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
243265009709	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
243265009710	hypothetical protein; Provisional; Region: PRK04860
243265009711	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
243265009712	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265009713	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265009714	active site
243265009715	Int/Topo IB signature motif; other site
243265009716	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265009717	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265009718	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265009719	interdomain interaction site; other site
243265009720	active site
243265009721	metal binding site [ion binding]; metal-binding site
243265009722	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265009723	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009724	non-specific DNA binding site [nucleotide binding]; other site
243265009725	salt bridge; other site
243265009726	sequence-specific DNA binding site [nucleotide binding]; other site
243265009727	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265009728	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265009729	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265009730	active site
243265009731	Int/Topo IB signature motif; other site
243265009732	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265009733	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265009734	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265009735	interdomain interaction site; other site
243265009736	active site
243265009737	metal binding site [ion binding]; metal-binding site
243265009738	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265009739	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009740	non-specific DNA binding site [nucleotide binding]; other site
243265009741	salt bridge; other site
243265009742	sequence-specific DNA binding site [nucleotide binding]; other site
243265009743	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265009744	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265009745	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265009746	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265009747	active site
243265009748	Int/Topo IB signature motif; other site
243265009749	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265009750	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265009751	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265009752	interdomain interaction site; other site
243265009753	active site
243265009754	metal binding site [ion binding]; metal-binding site
243265009755	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009756	non-specific DNA binding site [nucleotide binding]; other site
243265009757	salt bridge; other site
243265009758	sequence-specific DNA binding site [nucleotide binding]; other site
243265009759	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265009760	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265009761	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK01287
243265009762	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
243265009763	active site
243265009764	Int/Topo IB signature motif; other site
243265009765	CHC2 zinc finger; Region: zf-CHC2; cl17510
243265009766	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265009767	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265009768	interdomain interaction site; other site
243265009769	active site
243265009770	metal binding site [ion binding]; metal-binding site
243265009771	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265009772	non-specific DNA binding site [nucleotide binding]; other site
243265009773	salt bridge; other site
243265009774	sequence-specific DNA binding site [nucleotide binding]; other site
243265009775	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
243265009776	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
243265009777	haemagglutination activity domain; Region: Haemagg_act; pfam05860
243265009778	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
243265009779	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265009780	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265009781	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
243265009782	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
243265009783	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
243265009784	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
243265009785	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
243265009786	PAS fold; Region: PAS_4; pfam08448
243265009787	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265009788	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265009789	DNA binding residues [nucleotide binding]
243265009790	dimerization interface [polypeptide binding]; other site
243265009791	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
243265009792	PAS fold; Region: PAS_4; pfam08448
243265009793	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
243265009794	DNA binding residues [nucleotide binding]
243265009795	Homeodomain-like domain; Region: HTH_23; pfam13384
243265009796	Winged helix-turn helix; Region: HTH_29; pfam13551
243265009797	Winged helix-turn helix; Region: HTH_33; pfam13592
243265009798	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265009799	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265009800	Truncated gene. Some similarities with probable transcriptional regulator, LuxR family
243265009801	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
243265009802	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
243265009803	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
243265009804	amidohydrolase; Region: amidohydrolases; TIGR01891
243265009805	putative metal binding site [ion binding]; other site
243265009806	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
243265009807	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
243265009808	putative metal binding site [ion binding]; other site
243265009809	dimer interface [polypeptide binding]; other site
243265009810	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
243265009811	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265009812	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
243265009813	dimerization interface [polypeptide binding]; other site
243265009814	Homeodomain-like domain; Region: HTH_23; pfam13384
243265009815	Winged helix-turn helix; Region: HTH_29; pfam13551
243265009816	Winged helix-turn helix; Region: HTH_33; pfam13592
243265009817	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265009818	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265009819	PAS fold; Region: PAS_4; pfam08448
243265009820	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265009821	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
243265009822	DNA binding residues [nucleotide binding]
243265009823	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265009824	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
243265009825	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265009826	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265009827	homodimer interface [polypeptide binding]; other site
243265009828	catalytic residue [active]
243265009829	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
243265009830	Transcriptional regulators [Transcription]; Region: PurR; COG1609
243265009831	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
243265009832	DNA binding site [nucleotide binding]
243265009833	domain linker motif; other site
243265009834	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
243265009835	dimerization interface (closed form) [polypeptide binding]; other site
243265009836	ligand binding site [chemical binding]; other site
243265009837	PAS fold; Region: PAS_4; pfam08448
243265009838	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265009839	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265009840	DNA binding residues [nucleotide binding]
243265009841	dimerization interface [polypeptide binding]; other site
243265009842	PAS fold; Region: PAS_4; pfam08448
243265009843	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265009844	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
243265009845	DNA binding residues [nucleotide binding]
243265009846	dimerization interface [polypeptide binding]; other site
243265009847	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
243265009848	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
243265009849	Divalent cation transporter; Region: MgtE; pfam01769
243265009850	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
243265009851	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
243265009852	putative ligand binding residues [chemical binding]; other site
243265009853	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
243265009854	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
243265009855	NAD(P) binding site [chemical binding]; other site
243265009856	catalytic residues [active]
243265009857	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
243265009858	amino acid carrier protein; Region: agcS; TIGR00835
243265009859	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
243265009860	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
243265009861	N- and C-terminal domain interface [polypeptide binding]; other site
243265009862	active site
243265009863	MgATP binding site [chemical binding]; other site
243265009864	catalytic site [active]
243265009865	metal binding site [ion binding]; metal-binding site
243265009866	carbohydrate binding site [chemical binding]; other site
243265009867	putative homodimer interface [polypeptide binding]; other site
243265009868	tellurite resistance protein TehB; Provisional; Region: PRK12335
243265009869	Domain of unknown function (DUF1971); Region: DUF1971; pfam09313
243265009870	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265009871	S-adenosylmethionine binding site [chemical binding]; other site
243265009872	tyrosine kinase; Provisional; Region: PRK11519
243265009873	Chain length determinant protein; Region: Wzz; pfam02706
243265009874	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
243265009875	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
243265009876	Low molecular weight phosphatase family; Region: LMWPc; cd00115
243265009877	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
243265009878	active site
243265009879	polysaccharide export protein Wza; Provisional; Region: PRK15078
243265009880	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
243265009881	SLBB domain; Region: SLBB; pfam10531
243265009882	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
243265009883	active site
243265009884	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
243265009885	virion protein; Provisional; Region: V; PHA02564
243265009886	Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106
243265009887	putative glycosyl transferase; Provisional; Region: PRK10073
243265009888	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
243265009889	active site
243265009890	type III secretion system chaperone YscW; Region: YscW; TIGR02567
243265009891	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
243265009892	YopD protein; Region: YopD; pfam05844
243265009893	Secretion system effector C (SseC) like family; Region: SseC; pfam04888
243265009894	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
243265009895	binding surface
243265009896	TPR repeat; Region: TPR_11; pfam13414
243265009897	TPR motif; other site
243265009898	V antigen (LcrV) protein; Region: LcrV; pfam04792
243265009899	type III secretion protein LcrG; Region: LcrG_PcrG; TIGR02573
243265009900	type III secretion system regulator LcrR; Region: LcrR; TIGR02572
243265009901	type III secretion protein, HrcV family; Region: hrcV; TIGR01399
243265009902	FHIPEP family; Region: FHIPEP; pfam00771
243265009903	FHIPEP family; Region: FHIPEP; pfam00771
243265009904	type III secretion protein, YscX family; Region: type_III_YscX; TIGR02502
243265009905	type III secretion chaperone SycN; Region: type_III_SycN; TIGR02503
243265009906	TyeA; Region: TyeA; pfam09059
243265009907	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
243265009908	type III secretion system ATPase; Provisional; Region: PRK06936
243265009909	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
243265009910	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
243265009911	Walker A motif/ATP binding site; other site
243265009912	Walker B motif; other site
243265009913	Type III secretion protein YscO; Region: YscO; pfam07321
243265009914	type III secretion system needle length determinant; Region: type_III_yscP; TIGR02514
243265009915	type III secretion system protein; Validated; Region: PRK06933
243265009916	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
243265009917	type III secretion system protein YscR; Provisional; Region: PRK12797
243265009918	Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794
243265009919	Type III secretory pathway, component EscT [Intracellular trafficking and secretion]; Region: EscT; COG4791
243265009920	Type III secretory pathway, component EscU [Intracellular trafficking and secretion]; Region: EscU; COG4792
243265009921	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
243265009922	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265009923	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
243265009924	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
243265009925	cell division protein MukB; Provisional; Region: mukB; PRK04863
243265009926	type III secretion system chaperone, YscB family; Region: type_III_yscB; TIGR02513
243265009927	type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516
243265009928	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
243265009929	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
243265009930	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
243265009931	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
243265009932	type III secretion system protein SsaD; Provisional; Region: PRK15367
243265009933	Protein of unknown function (DUF1895); Region: DUF1895; pfam08988
243265009934	Type III secretion needle MxiH like; Region: MxiH; cl09641
243265009935	type III secretion protein, YscG family; Region: type_III_yscG; TIGR02508
243265009936	YopR Core; Region: YopR_core; pfam09025
243265009937	Type III secretion needle MxiH like; Region: MxiH; cl09641
243265009938	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
243265009939	YOP proteins translocation protein K (YscK); Region: YscK; pfam06578
243265009940	type III secretion system protein; Reviewed; Region: PRK06937
243265009941	Flagellar assembly protein FliH; Region: FliH; pfam02108
243265009942	Yersinia/Haemophilus virulence surface antigen; Region: Peptidase_C58; pfam03543
243265009943	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
243265009944	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
243265009945	DNA-binding site [nucleotide binding]; DNA binding site
243265009946	RNA-binding motif; other site
243265009947	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
243265009948	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265009949	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
243265009950	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265009951	Walker A motif; other site
243265009952	ATP binding site [chemical binding]; other site
243265009953	acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920
243265009954	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
243265009955	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
243265009956	active site
243265009957	iron coordination sites [ion binding]; other site
243265009958	substrate binding pocket [chemical binding]; other site
243265009959	Predicted permeases [General function prediction only]; Region: COG0679
243265009960	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265009961	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
243265009962	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
243265009963	active site
243265009964	HIGH motif; other site
243265009965	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
243265009966	KMSKS motif; other site
243265009967	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
243265009968	tRNA binding surface [nucleotide binding]; other site
243265009969	anticodon binding site; other site
243265009970	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
243265009971	substrate binding site [chemical binding]; other site
243265009972	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
243265009973	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
243265009974	putative active site [active]
243265009975	putative metal binding site [ion binding]; other site
243265009976	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
243265009977	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
243265009978	ATP-grasp domain; Region: ATP-grasp; pfam02222
243265009979	Truncated gene. Similar to transposase, IS630 family (ISPlu10-p)
243265009980	Truncated gene. Similar to transposase
243265009981	putative transposase; Provisional; Region: PRK09857
243265009982	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265009983	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
243265009984	Lumazine binding domain; Region: Lum_binding; pfam00677
243265009985	Lumazine binding domain; Region: Lum_binding; pfam00677
243265009986	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; cl04114
243265009987	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265009988	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265009989	putative substrate translocation pore; other site
243265009990	pyrimidine utilization protein A; Region: RutA; TIGR03612
243265009991	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
243265009992	active site
243265009993	dimer interface [polypeptide binding]; other site
243265009994	non-prolyl cis peptide bond; other site
243265009995	insertion regions; other site
243265009996	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
243265009997	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
243265009998	FtsX-like permease family; Region: FtsX; pfam02687
243265009999	FtsX-like permease family; Region: FtsX; pfam02687
243265010000	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
243265010001	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
243265010002	Walker A/P-loop; other site
243265010003	ATP binding site [chemical binding]; other site
243265010004	Q-loop/lid; other site
243265010005	ABC transporter signature motif; other site
243265010006	Walker B; other site
243265010007	D-loop; other site
243265010008	H-loop/switch region; other site
243265010009	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
243265010010	active site
243265010011	catalytic triad [active]
243265010012	oxyanion hole [active]
243265010013	switch loop; other site
243265010014	oxidoreductase; Provisional; Region: PRK08017
243265010015	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
243265010016	NADP binding site [chemical binding]; other site
243265010017	active site
243265010018	steroid binding site; other site
243265010019	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
243265010020	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
243265010021	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
243265010022	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
243265010023	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
243265010024	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
243265010025	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
243265010026	DNA binding residues [nucleotide binding]
243265010027	dimer interface [polypeptide binding]; other site
243265010028	copper binding site [ion binding]; other site
243265010029	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
243265010030	metal-binding site [ion binding]
243265010031	copper exporting ATPase; Provisional; Region: copA; PRK10671
243265010032	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
243265010033	metal-binding site [ion binding]
243265010034	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
243265010035	metal-binding site [ion binding]
243265010036	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
243265010037	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265010038	motif II; other site
243265010039	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
243265010040	TraB family; Region: TraB; cl12050
243265010041	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
243265010042	putative deacylase active site [active]
243265010043	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
243265010044	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
243265010045	active site
243265010046	metal binding site [ion binding]; metal-binding site
243265010047	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
243265010048	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010049	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265010050	putative substrate translocation pore; other site
243265010051	putative cation:proton antiport protein; Provisional; Region: PRK10669
243265010052	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
243265010053	TrkA-N domain; Region: TrkA_N; pfam02254
243265010054	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
243265010055	inosine/guanosine kinase; Provisional; Region: PRK15074
243265010056	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
243265010057	substrate binding site [chemical binding]; other site
243265010058	ATP binding site [chemical binding]; other site
243265010059	LPS O-antigen length regulator; Provisional; Region: PRK10381
243265010060	Chain length determinant protein; Region: Wzz; pfam02706
243265010061	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
243265010062	ferrochelatase; Reviewed; Region: hemH; PRK00035
243265010063	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
243265010064	C-terminal domain interface [polypeptide binding]; other site
243265010065	active site
243265010066	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
243265010067	active site
243265010068	N-terminal domain interface [polypeptide binding]; other site
243265010069	adenylate kinase; Reviewed; Region: adk; PRK00279
243265010070	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
243265010071	AMP-binding site [chemical binding]; other site
243265010072	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
243265010073	heat shock protein 90; Provisional; Region: PRK05218
243265010074	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265010075	ATP binding site [chemical binding]; other site
243265010076	Mg2+ binding site [ion binding]; other site
243265010077	G-X-G motif; other site
243265010078	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
243265010079	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265010080	N-terminal plug; other site
243265010081	ligand-binding site [chemical binding]; other site
243265010082	recombination protein RecR; Reviewed; Region: recR; PRK00076
243265010083	RecR protein; Region: RecR; pfam02132
243265010084	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
243265010085	putative active site [active]
243265010086	putative metal-binding site [ion binding]; other site
243265010087	tetramer interface [polypeptide binding]; other site
243265010088	hypothetical protein; Validated; Region: PRK00153
243265010089	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
243265010090	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265010091	Walker A motif; other site
243265010092	ATP binding site [chemical binding]; other site
243265010093	Walker B motif; other site
243265010094	DNA polymerase III subunit delta'; Validated; Region: PRK08485
243265010095	arginine finger; other site
243265010096	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
243265010097	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
243265010098	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
243265010099	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265010100	active site
243265010101	Primosomal replication protein priB and priC; Region: priB_priC; pfam07445
243265010102	hypothetical protein; Provisional; Region: PRK11038
243265010103	Protein of unknown function (DUF1284); Region: DUF1284; cl01419
243265010104	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; cl17304
243265010105	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
243265010106	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
243265010107	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
243265010108	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
243265010109	Walker A/P-loop; other site
243265010110	ATP binding site [chemical binding]; other site
243265010111	Q-loop/lid; other site
243265010112	ABC transporter signature motif; other site
243265010113	Walker B; other site
243265010114	D-loop; other site
243265010115	H-loop/switch region; other site
243265010116	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
243265010117	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
243265010118	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
243265010119	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
243265010120	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265010121	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265010122	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
243265010123	Protein export membrane protein; Region: SecD_SecF; cl14618
243265010124	gene expression modulator; Provisional; Region: PRK10945
243265010125	Type III secretion system lipoprotein chaperone (YscW); Region: YscW; cl15825
243265010126	acyl-CoA thioesterase II; Provisional; Region: PRK10526
243265010127	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
243265010128	active site
243265010129	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
243265010130	catalytic triad [active]
243265010131	dimer interface [polypeptide binding]; other site
243265010132	ammonium transporter; Provisional; Region: PRK10666
243265010133	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
243265010134	Nitrogen regulatory protein P-II; Region: P-II; smart00938
243265010135	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
243265010136	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265010137	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
243265010138	Walker A/P-loop; other site
243265010139	ATP binding site [chemical binding]; other site
243265010140	Q-loop/lid; other site
243265010141	ABC transporter signature motif; other site
243265010142	Walker B; other site
243265010143	D-loop; other site
243265010144	H-loop/switch region; other site
243265010145	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
243265010146	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
243265010147	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265010148	Walker A/P-loop; other site
243265010149	ATP binding site [chemical binding]; other site
243265010150	Q-loop/lid; other site
243265010151	ABC transporter signature motif; other site
243265010152	Walker B; other site
243265010153	D-loop; other site
243265010154	H-loop/switch region; other site
243265010155	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
243265010156	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
243265010157	putative DNA binding site [nucleotide binding]; other site
243265010158	putative Zn2+ binding site [ion binding]; other site
243265010159	AsnC family; Region: AsnC_trans_reg; pfam01037
243265010160	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
243265010161	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
243265010162	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265010163	catalytic residue [active]
243265010164	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
243265010165	Ligand Binding Site [chemical binding]; other site
243265010166	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
243265010167	active site
243265010168	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
243265010169	periplasmic folding chaperone; Provisional; Region: PRK10788
243265010170	SurA N-terminal domain; Region: SurA_N_3; cl07813
243265010171	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
243265010172	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
243265010173	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
243265010174	IHF dimer interface [polypeptide binding]; other site
243265010175	IHF - DNA interface [nucleotide binding]; other site
243265010176	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
243265010177	Found in ATP-dependent protease La (LON); Region: LON; smart00464
243265010178	Found in ATP-dependent protease La (LON); Region: LON; smart00464
243265010179	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265010180	Walker A motif; other site
243265010181	ATP binding site [chemical binding]; other site
243265010182	Walker B motif; other site
243265010183	arginine finger; other site
243265010184	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
243265010185	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
243265010186	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
243265010187	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265010188	Walker A motif; other site
243265010189	ATP binding site [chemical binding]; other site
243265010190	Walker B motif; other site
243265010191	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
243265010192	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
243265010193	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
243265010194	oligomer interface [polypeptide binding]; other site
243265010195	active site residues [active]
243265010196	trigger factor; Provisional; Region: tig; PRK01490
243265010197	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
243265010198	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
243265010199	transcriptional regulator BolA; Provisional; Region: PRK11628
243265010200	hypothetical protein; Provisional; Region: PRK11627
243265010201	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
243265010202	muropeptide transporter; Reviewed; Region: ampG; PRK11902
243265010203	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010204	putative substrate translocation pore; other site
243265010205	hypothetical protein; Provisional; Region: PRK11528
243265010206	cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433
243265010207	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
243265010208	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
243265010209	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
243265010210	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
243265010211	D-pathway; other site
243265010212	Putative ubiquinol binding site [chemical binding]; other site
243265010213	Low-spin heme (heme b) binding site [chemical binding]; other site
243265010214	Putative water exit pathway; other site
243265010215	Binuclear center (heme o3/CuB) [ion binding]; other site
243265010216	K-pathway; other site
243265010217	Putative proton exit pathway; other site
243265010218	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
243265010219	Subunit I/III interface [polypeptide binding]; other site
243265010220	Subunit III/IV interface [polypeptide binding]; other site
243265010221	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
243265010222	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
243265010223	UbiA prenyltransferase family; Region: UbiA; pfam01040
243265010224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010225	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265010226	putative substrate translocation pore; other site
243265010227	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
243265010228	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
243265010229	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
243265010230	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
243265010231	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
243265010232	Truncated gene. Highly similar to the N-terminal region of 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme ThiJ
243265010233	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
243265010234	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
243265010235	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
243265010236	Ligand Binding Site [chemical binding]; other site
243265010237	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
243265010238	active site residue [active]
243265010239	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
243265010240	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
243265010241	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
243265010242	substrate binding pocket [chemical binding]; other site
243265010243	chain length determination region; other site
243265010244	substrate-Mg2+ binding site; other site
243265010245	catalytic residues [active]
243265010246	aspartate-rich region 1; other site
243265010247	active site lid residues [active]
243265010248	aspartate-rich region 2; other site
243265010249	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
243265010250	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
243265010251	TPP-binding site; other site
243265010252	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
243265010253	PYR/PP interface [polypeptide binding]; other site
243265010254	dimer interface [polypeptide binding]; other site
243265010255	TPP binding site [chemical binding]; other site
243265010256	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
243265010257	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
243265010258	Truncated gene. Similar to N-terminal region of transposase, IS982 family (ISPlu6-p/ISPlu11-p)
243265010259	Truncated gene. Similar to C-terminal region of transposase, IS982 family (ISPlu6-p/ISPlu11-p)
243265010260	Truncated gene. Some similarities with Unknown protein
243265010261	RelB antitoxin; Region: RelB; cl01171
243265010262	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
243265010263	tetramer interfaces [polypeptide binding]; other site
243265010264	binuclear metal-binding site [ion binding]; other site
243265010265	thiamine monophosphate kinase; Provisional; Region: PRK05731
243265010266	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
243265010267	ATP binding site [chemical binding]; other site
243265010268	dimerization interface [polypeptide binding]; other site
243265010269	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
243265010270	putative RNA binding site [nucleotide binding]; other site
243265010271	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
243265010272	homopentamer interface [polypeptide binding]; other site
243265010273	active site
243265010274	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
243265010275	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
243265010276	catalytic motif [active]
243265010277	Zn binding site [ion binding]; other site
243265010278	RibD C-terminal domain; Region: RibD_C; cl17279
243265010279	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
243265010280	ATP cone domain; Region: ATP-cone; pfam03477
243265010281	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
243265010282	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
243265010283	Protein export membrane protein; Region: SecD_SecF; pfam02355
243265010284	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
243265010285	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
243265010286	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
243265010287	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
243265010288	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
243265010289	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
243265010290	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
243265010291	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
243265010292	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
243265010293	Protein of unknown function, DUF479; Region: DUF479; cl01203
243265010294	peroxidase; Provisional; Region: PRK15000
243265010295	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
243265010296	dimer interface [polypeptide binding]; other site
243265010297	decamer (pentamer of dimers) interface [polypeptide binding]; other site
243265010298	catalytic triad [active]
243265010299	peroxidatic and resolving cysteines [active]
243265010300	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
243265010301	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
243265010302	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
243265010303	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
243265010304	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
243265010305	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
243265010306	putative active site [active]
243265010307	heme pocket [chemical binding]; other site
243265010308	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265010309	dimer interface [polypeptide binding]; other site
243265010310	phosphorylation site [posttranslational modification]
243265010311	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265010312	ATP binding site [chemical binding]; other site
243265010313	Mg2+ binding site [ion binding]; other site
243265010314	G-X-G motif; other site
243265010315	transcriptional regulator PhoB; Provisional; Region: PRK10161
243265010316	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265010317	active site
243265010318	phosphorylation site [posttranslational modification]
243265010319	intermolecular recognition site; other site
243265010320	dimerization interface [polypeptide binding]; other site
243265010321	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
243265010322	DNA binding site [nucleotide binding]
243265010323	exonuclease subunit SbcD; Provisional; Region: PRK10966
243265010324	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
243265010325	active site
243265010326	metal binding site [ion binding]; metal-binding site
243265010327	DNA binding site [nucleotide binding]
243265010328	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
243265010329	exonuclease subunit SbcC; Provisional; Region: PRK10246
243265010330	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265010331	Walker A/P-loop; other site
243265010332	ATP binding site [chemical binding]; other site
243265010333	Q-loop/lid; other site
243265010334	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265010335	ABC transporter signature motif; other site
243265010336	Walker B; other site
243265010337	D-loop; other site
243265010338	H-loop/switch region; other site
243265010339	putative transposase; Provisional; Region: PRK09857
243265010340	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265010341	Creatinine amidohydrolase; Region: Creatininase; pfam02633
243265010342	Dihydroorotate dehydrogenase (DHOD) and Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the...; Region: DHOD_DHPD_FMN; cd02810
243265010343	active site
243265010344	FMN binding site [chemical binding]; other site
243265010345	substrate binding site [chemical binding]; other site
243265010346	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; cl17818
243265010347	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
243265010348	Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Region: HemL; COG0001
243265010349	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265010350	inhibitor-cofactor binding pocket; inhibition site
243265010351	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265010352	catalytic residue [active]
243265010353	Truncated gene. Some similarities with polyketide synthase type I
243265010354	Condensation domain; Region: Condensation; pfam00668
243265010355	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
243265010356	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
243265010357	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265010358	CoA binding site [chemical binding]; other site
243265010359	peptide synthase; Provisional; Region: PRK12467
243265010360	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
243265010361	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010362	putative substrate translocation pore; other site
243265010363	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010364	Protein of unknown function (DUF1062); Region: DUF1062; pfam06353
243265010365	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2; cl00208
243265010366	CAS motifs; other site
243265010367	active site
243265010368	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
243265010369	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
243265010370	active site
243265010371	metal binding site [ion binding]; metal-binding site
243265010372	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
243265010373	tRNA synthetases class I (K); Region: tRNA-synt_1f; pfam01921
243265010374	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
243265010375	active site
243265010376	nucleotide binding site [chemical binding]; other site
243265010377	HIGH motif; other site
243265010378	KMSKS motif; other site
243265010379	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
243265010380	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
243265010381	NAD(P) binding site [chemical binding]; other site
243265010382	catalytic residues [active]
243265010383	recombination associated protein; Reviewed; Region: rdgC; PRK00321
243265010384	Fic family protein [Function unknown]; Region: COG3177
243265010385	Fic/DOC family; Region: Fic; pfam02661
243265010386	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
243265010387	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
243265010388	Domain of unknown function DUF29; Region: DUF29; pfam01724
243265010389	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
243265010390	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
243265010391	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265010392	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265010393	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
243265010394	putative effector binding pocket; other site
243265010395	dimerization interface [polypeptide binding]; other site
243265010396	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
243265010397	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010398	putative substrate translocation pore; other site
243265010399	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265010400	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265010401	non-specific DNA binding site [nucleotide binding]; other site
243265010402	salt bridge; other site
243265010403	sequence-specific DNA binding site [nucleotide binding]; other site
243265010404	Domain of unknown function (DUF955); Region: DUF955; cl01076
243265010405	biopolymer transport protein ExbD; Provisional; Region: PRK11267
243265010406	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
243265010407	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
243265010408	cystathionine beta-lyase; Provisional; Region: PRK08114
243265010409	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
243265010410	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265010411	catalytic residue [active]
243265010412	putative regulator PrlF; Provisional; Region: PRK09974
243265010413	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
243265010414	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
243265010415	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
243265010416	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
243265010417	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
243265010418	active site
243265010419	catalytic tetrad [active]
243265010420	FtsI repressor; Provisional; Region: PRK10883
243265010421	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
243265010422	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
243265010423	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
243265010424	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
243265010425	putative acyl-acceptor binding pocket; other site
243265010426	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
243265010427	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
243265010428	CAP-like domain; other site
243265010429	active site
243265010430	primary dimer interface [polypeptide binding]; other site
243265010431	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
243265010432	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265010433	ATP binding site [chemical binding]; other site
243265010434	Mg2+ binding site [ion binding]; other site
243265010435	G-X-G motif; other site
243265010436	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
243265010437	anchoring element; other site
243265010438	dimer interface [polypeptide binding]; other site
243265010439	ATP binding site [chemical binding]; other site
243265010440	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
243265010441	active site
243265010442	metal binding site [ion binding]; metal-binding site
243265010443	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
243265010444	esterase YqiA; Provisional; Region: PRK11071
243265010445	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
243265010446	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
243265010447	active site
243265010448	metal binding site [ion binding]; metal-binding site
243265010449	hexamer interface [polypeptide binding]; other site
243265010450	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
243265010451	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
243265010452	dimer interface [polypeptide binding]; other site
243265010453	ADP-ribose binding site [chemical binding]; other site
243265010454	active site
243265010455	nudix motif; other site
243265010456	metal binding site [ion binding]; metal-binding site
243265010457	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
243265010458	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
243265010459	hypothetical protein; Provisional; Region: PRK11653
243265010460	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
243265010461	Homeodomain-like domain; Region: HTH_23; pfam13384
243265010462	Winged helix-turn helix; Region: HTH_29; pfam13551
243265010463	Winged helix-turn helix; Region: HTH_33; pfam13592
243265010464	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265010465	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265010466	Predicted transcriptional regulator [Transcription]; Region: COG3905
243265010467	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
243265010468	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
243265010469	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
243265010470	putative active site [active]
243265010471	metal binding site [ion binding]; metal-binding site
243265010472	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
243265010473	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
243265010474	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
243265010475	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4380
243265010476	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4259
243265010477	Uncharacterized protein involved in formation of curli polymers [Cell envelope biogenesis, outer membrane]; Region: CsgG; COG1462
243265010478	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
243265010479	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
243265010480	putative ribose interaction site [chemical binding]; other site
243265010481	putative ADP binding site [chemical binding]; other site
243265010482	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
243265010483	active site
243265010484	nucleotide binding site [chemical binding]; other site
243265010485	HIGH motif; other site
243265010486	KMSKS motif; other site
243265010487	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
243265010488	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
243265010489	metal binding triad; other site
243265010490	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
243265010491	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
243265010492	metal binding triad; other site
243265010493	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
243265010494	Uncharacterized conserved protein [Function unknown]; Region: COG3025
243265010495	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
243265010496	putative active site [active]
243265010497	putative metal binding residues [ion binding]; other site
243265010498	signature motif; other site
243265010499	putative triphosphate binding site [ion binding]; other site
243265010500	Bacterial SH3 domain homologues; Region: SH3b; smart00287
243265010501	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
243265010502	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
243265010503	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
243265010504	active site
243265010505	NTP binding site [chemical binding]; other site
243265010506	metal binding triad [ion binding]; metal-binding site
243265010507	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
243265010508	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
243265010509	Zn2+ binding site [ion binding]; other site
243265010510	Mg2+ binding site [ion binding]; other site
243265010511	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
243265010512	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
243265010513	homooctamer interface [polypeptide binding]; other site
243265010514	active site
243265010515	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
243265010516	UGMP family protein; Validated; Region: PRK09604
243265010517	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
243265010518	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
243265010519	DNA primase; Validated; Region: dnaG; PRK05667
243265010520	CHC2 zinc finger; Region: zf-CHC2; pfam01807
243265010521	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
243265010522	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
243265010523	active site
243265010524	metal binding site [ion binding]; metal-binding site
243265010525	interdomain interaction site; other site
243265010526	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
243265010527	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
243265010528	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
243265010529	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
243265010530	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
243265010531	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
243265010532	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265010533	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
243265010534	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265010535	DNA binding residues [nucleotide binding]
243265010536	Prophage antirepressor [Transcription]; Region: COG3617
243265010537	BRO family, N-terminal domain; Region: Bro-N; smart01040
243265010538	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
243265010539	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265010540	non-specific DNA binding site [nucleotide binding]; other site
243265010541	salt bridge; other site
243265010542	sequence-specific DNA binding site [nucleotide binding]; other site
243265010543	Methyltransferase domain; Region: Methyltransf_23; pfam13489
243265010544	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265010545	S-adenosylmethionine binding site [chemical binding]; other site
243265010546	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
243265010547	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
243265010548	active site
243265010549	metal binding site [ion binding]; metal-binding site
243265010550	nudix motif; other site
243265010551	Protein of unknown function (DUF535); Region: DUF535; pfam04393
243265010552	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
243265010553	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
243265010554	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
243265010555	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
243265010556	active site
243265010557	FMN binding site [chemical binding]; other site
243265010558	2,4-decadienoyl-CoA binding site; other site
243265010559	catalytic residue [active]
243265010560	4Fe-4S cluster binding site [ion binding]; other site
243265010561	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
243265010562	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265010563	serine/threonine transporter SstT; Provisional; Region: PRK13628
243265010564	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
243265010565	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
243265010566	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
243265010567	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
243265010568	Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957
243265010569	Predicted membrane protein [Function unknown]; Region: COG5393
243265010570	YqjK-like protein; Region: YqjK; pfam13997
243265010571	Predicted membrane protein [Function unknown]; Region: COG2259
243265010572	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265010573	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
243265010574	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
243265010575	dimerization interface [polypeptide binding]; other site
243265010576	Pirin-related protein [General function prediction only]; Region: COG1741
243265010577	Pirin; Region: Pirin; pfam02678
243265010578	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
243265010579	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
243265010580	putative SAM binding site [chemical binding]; other site
243265010581	putative homodimer interface [polypeptide binding]; other site
243265010582	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
243265010583	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
243265010584	putative ligand binding site [chemical binding]; other site
243265010585	hypothetical protein; Reviewed; Region: PRK12497
243265010586	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
243265010587	dimer interface [polypeptide binding]; other site
243265010588	active site
243265010589	outer membrane lipoprotein; Provisional; Region: PRK11023
243265010590	BON domain; Region: BON; pfam04972
243265010591	BON domain; Region: BON; pfam04972
243265010592	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
243265010593	Transglycosylase; Region: Transgly; cl17702
243265010594	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
243265010595	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
243265010596	conserved cys residue [active]
243265010597	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
243265010598	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
243265010599	putative active site [active]
243265010600	heme pocket [chemical binding]; other site
243265010601	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265010602	dimer interface [polypeptide binding]; other site
243265010603	phosphorylation site [posttranslational modification]
243265010604	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265010605	ATP binding site [chemical binding]; other site
243265010606	Mg2+ binding site [ion binding]; other site
243265010607	G-X-G motif; other site
243265010608	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265010609	active site
243265010610	phosphorylation site [posttranslational modification]
243265010611	intermolecular recognition site; other site
243265010612	dimerization interface [polypeptide binding]; other site
243265010613	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
243265010614	putative binding surface; other site
243265010615	active site
243265010616	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
243265010617	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
243265010618	active site
243265010619	dimer interface [polypeptide binding]; other site
243265010620	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
243265010621	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
243265010622	active site
243265010623	FMN binding site [chemical binding]; other site
243265010624	substrate binding site [chemical binding]; other site
243265010625	3Fe-4S cluster binding site [ion binding]; other site
243265010626	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
243265010627	domain interface; other site
243265010628	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
243265010629	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
243265010630	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265010631	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
243265010632	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
243265010633	stringent starvation protein A; Provisional; Region: sspA; PRK09481
243265010634	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
243265010635	C-terminal domain interface [polypeptide binding]; other site
243265010636	putative GSH binding site (G-site) [chemical binding]; other site
243265010637	dimer interface [polypeptide binding]; other site
243265010638	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
243265010639	dimer interface [polypeptide binding]; other site
243265010640	N-terminal domain interface [polypeptide binding]; other site
243265010641	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
243265010642	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
243265010643	23S rRNA interface [nucleotide binding]; other site
243265010644	L3 interface [polypeptide binding]; other site
243265010645	Predicted ATPase [General function prediction only]; Region: COG1485
243265010646	hypothetical protein; Provisional; Region: PRK11677
243265010647	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
243265010648	serine endoprotease; Provisional; Region: PRK10139
243265010649	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
243265010650	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
243265010651	protein binding site [polypeptide binding]; other site
243265010652	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
243265010653	Truncated transposase. Similar to C-terminal region of transposase
243265010654	Truncated transposase. Similar to N-terminal region of transposase
243265010655	Truncated gene, similar to virulence-associated protein
243265010656	serine endoprotease; Provisional; Region: PRK10898
243265010657	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
243265010658	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
243265010659	protein binding site [polypeptide binding]; other site
243265010660	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
243265010661	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
243265010662	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265010663	Walker A/P-loop; other site
243265010664	ATP binding site [chemical binding]; other site
243265010665	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
243265010666	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
243265010667	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
243265010668	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
243265010669	hinge; other site
243265010670	active site
243265010671	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
243265010672	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
243265010673	anti sigma factor interaction site; other site
243265010674	regulatory phosphorylation site [posttranslational modification]; other site
243265010675	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
243265010676	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
243265010677	mce related protein; Region: MCE; pfam02470
243265010678	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
243265010679	conserved hypothetical integral membrane protein; Region: TIGR00056
243265010680	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
243265010681	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
243265010682	Walker A/P-loop; other site
243265010683	ATP binding site [chemical binding]; other site
243265010684	Q-loop/lid; other site
243265010685	ABC transporter signature motif; other site
243265010686	Walker B; other site
243265010687	D-loop; other site
243265010688	H-loop/switch region; other site
243265010689	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
243265010690	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
243265010691	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
243265010692	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
243265010693	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
243265010694	putative active site [active]
243265010695	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
243265010696	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
243265010697	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
243265010698	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
243265010699	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
243265010700	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
243265010701	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
243265010702	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
243265010703	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
243265010704	Walker A/P-loop; other site
243265010705	ATP binding site [chemical binding]; other site
243265010706	Q-loop/lid; other site
243265010707	ABC transporter signature motif; other site
243265010708	Walker B; other site
243265010709	D-loop; other site
243265010710	H-loop/switch region; other site
243265010711	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
243265010712	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
243265010713	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
243265010714	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
243265010715	30S subunit binding site; other site
243265010716	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
243265010717	active site
243265010718	phosphorylation site [posttranslational modification]
243265010719	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
243265010720	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
243265010721	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
243265010722	dimerization domain swap beta strand [polypeptide binding]; other site
243265010723	regulatory protein interface [polypeptide binding]; other site
243265010724	active site
243265010725	regulatory phosphorylation site [posttranslational modification]; other site
243265010726	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
243265010727	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
243265010728	Similar to the N-terminal region of Ner-like protein.  truncated protein
243265010729	Truncated gene. Some similarities with the C-terminal region of Ner-like DNA-binding protein.
243265010730	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265010731	Truncated gene. Some similarities with the C-terminal region of Unknown protein of Photorhabdus luminescens
243265010732	Truncated gene. Some similarities with the C-terminal region of bacteriophage protein
243265010733	Truncated gene. Some similarities with the N-terminal region of bacteriophage protein
243265010734	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
243265010735	peptidase PmbA; Provisional; Region: PRK11040
243265010736	hypothetical protein; Provisional; Region: PRK05255
243265010737	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
243265010738	RNAase interaction site [polypeptide binding]; other site
243265010739	microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential  for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th,  Pb, N1, and Ms) and...; Region: microbial_RNases; cl00212
243265010740	active site
243265010741	protease TldD; Provisional; Region: tldD; PRK10735
243265010742	nitrilase; Region: PLN02798
243265010743	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
243265010744	putative active site [active]
243265010745	catalytic triad [active]
243265010746	dimer interface [polypeptide binding]; other site
243265010747	hypothetical protein; Provisional; Region: PRK10899
243265010748	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
243265010749	ribonuclease G; Provisional; Region: PRK11712
243265010750	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
243265010751	homodimer interface [polypeptide binding]; other site
243265010752	oligonucleotide binding site [chemical binding]; other site
243265010753	Maf-like protein; Region: Maf; pfam02545
243265010754	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
243265010755	active site
243265010756	dimer interface [polypeptide binding]; other site
243265010757	rod shape-determining protein MreD; Provisional; Region: PRK11060
243265010758	rod shape-determining protein MreC; Region: mreC; TIGR00219
243265010759	rod shape-determining protein MreC; Region: MreC; pfam04085
243265010760	rod shape-determining protein MreB; Provisional; Region: PRK13927
243265010761	MreB and similar proteins; Region: MreB_like; cd10225
243265010762	nucleotide binding site [chemical binding]; other site
243265010763	Mg binding site [ion binding]; other site
243265010764	putative protofilament interaction site [polypeptide binding]; other site
243265010765	RodZ interaction site [polypeptide binding]; other site
243265010766	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
243265010767	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
243265010768	NADP binding site [chemical binding]; other site
243265010769	dimer interface [polypeptide binding]; other site
243265010770	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
243265010771	Dehydroquinase class II; Region: DHquinase_II; pfam01220
243265010772	active site
243265010773	trimer interface [polypeptide binding]; other site
243265010774	dimer interface [polypeptide binding]; other site
243265010775	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
243265010776	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
243265010777	carboxyltransferase (CT) interaction site; other site
243265010778	biotinylation site [posttranslational modification]; other site
243265010779	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
243265010780	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
243265010781	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
243265010782	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
243265010783	Homeodomain-like domain; Region: HTH_23; pfam13384
243265010784	Winged helix-turn helix; Region: HTH_29; pfam13551
243265010785	Winged helix-turn helix; Region: HTH_33; pfam13592
243265010786	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265010787	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265010788	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
243265010789	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
243265010790	tartrate dehydrogenase; Region: TTC; TIGR02089
243265010791	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Region: CinA; COG1058
243265010792	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
243265010793	putative MPT binding site; other site
243265010794	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
243265010795	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
243265010796	active site
243265010797	metal binding site [ion binding]; metal-binding site
243265010798	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
243265010799	Transposase [DNA replication, recombination, and repair]; Region: COG5421
243265010800	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
243265010801	catalytic residues [active]
243265010802	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
243265010803	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010804	putative substrate translocation pore; other site
243265010805	hypothetical protein; Provisional; Region: PRK10633
243265010806	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
243265010807	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
243265010808	Na binding site [ion binding]; other site
243265010809	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
243265010810	Methyltransferase domain; Region: Methyltransf_18; pfam12847
243265010811	S-adenosylmethionine binding site [chemical binding]; other site
243265010812	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
243265010813	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
243265010814	FMN binding site [chemical binding]; other site
243265010815	active site
243265010816	catalytic residues [active]
243265010817	substrate binding site [chemical binding]; other site
243265010818	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
243265010819	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
243265010820	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010821	putative substrate translocation pore; other site
243265010822	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
243265010823	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
243265010824	delta endotoxin, N-terminal domain; Region: Endotoxin_N; pfam03945
243265010825	Jacalin-like lectin domain; Region: Jacalin_like; cd09302
243265010826	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
243265010827	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
243265010828	Walker A/P-loop; other site
243265010829	ATP binding site [chemical binding]; other site
243265010830	Q-loop/lid; other site
243265010831	ABC transporter signature motif; other site
243265010832	Walker B; other site
243265010833	D-loop; other site
243265010834	H-loop/switch region; other site
243265010835	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
243265010836	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
243265010837	Walker A/P-loop; other site
243265010838	ATP binding site [chemical binding]; other site
243265010839	Q-loop/lid; other site
243265010840	ABC transporter signature motif; other site
243265010841	Walker B; other site
243265010842	D-loop; other site
243265010843	H-loop/switch region; other site
243265010844	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
243265010845	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
243265010846	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
243265010847	TM-ABC transporter signature motif; other site
243265010848	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
243265010849	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
243265010850	TM-ABC transporter signature motif; other site
243265010851	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
243265010852	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
243265010853	dimerization interface [polypeptide binding]; other site
243265010854	ligand binding site [chemical binding]; other site
243265010855	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
243265010856	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
243265010857	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
243265010858	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265010859	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265010860	DNA binding residues [nucleotide binding]
243265010861	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
243265010862	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
243265010863	cell division protein FtsE; Provisional; Region: PRK10908
243265010864	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265010865	Walker A/P-loop; other site
243265010866	ATP binding site [chemical binding]; other site
243265010867	Q-loop/lid; other site
243265010868	ABC transporter signature motif; other site
243265010869	Walker B; other site
243265010870	D-loop; other site
243265010871	H-loop/switch region; other site
243265010872	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
243265010873	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
243265010874	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
243265010875	P loop; other site
243265010876	GTP binding site [chemical binding]; other site
243265010877	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
243265010878	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265010879	S-adenosylmethionine binding site [chemical binding]; other site
243265010880	hypothetical protein; Provisional; Region: PRK10910
243265010881	Predicted membrane protein [Function unknown]; Region: COG3714
243265010882	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
243265010883	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
243265010884	metal-binding site [ion binding]
243265010885	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
243265010886	Soluble P-type ATPase [General function prediction only]; Region: COG4087
243265010887	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
243265010888	CPxP  motif; other site
243265010889	hypothetical protein; Provisional; Region: PRK11212
243265010890	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265010891	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265010892	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
243265010893	Truncated gene. Similar to the C-terminal region of L-fuculokinase
243265010894	Truncated gene. Weakly similar to the central region of L-fuculokinase.
243265010895	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
243265010896	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
243265010897	dimer interface [polypeptide binding]; other site
243265010898	active site
243265010899	metal binding site [ion binding]; metal-binding site
243265010900	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
243265010901	Domain of unknown function DUF29; Region: DUF29; pfam01724
243265010902	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
243265010903	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265010904	putative substrate translocation pore; other site
243265010905	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
243265010906	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
243265010907	active site
243265010908	catalytic site [active]
243265010909	metal binding site [ion binding]; metal-binding site
243265010910	poxB regulator PoxA; Provisional; Region: PRK09350
243265010911	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
243265010912	motif 1; other site
243265010913	dimer interface [polypeptide binding]; other site
243265010914	active site
243265010915	motif 2; other site
243265010916	motif 3; other site
243265010917	Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; Region: Fascin; cl00187
243265010918	PKC phosphorylation site [posttranslational modification]; other site
243265010919	Homeodomain-like domain; Region: HTH_23; pfam13384
243265010920	Winged helix-turn helix; Region: HTH_29; pfam13551
243265010921	Winged helix-turn helix; Region: HTH_33; pfam13592
243265010922	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265010923	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265010924	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
243265010925	L-aspartate oxidase; Provisional; Region: PRK06175
243265010926	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
243265010927	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
243265010928	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
243265010929	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
243265010930	D-subunit interface [polypeptide binding]; other site
243265010931	Iron-sulfur protein interface; other site
243265010932	proximal quinone binding site [chemical binding]; other site
243265010933	distal quinone binding site [chemical binding]; other site
243265010934	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
243265010935	Iron-sulfur protein interface; other site
243265010936	proximal quinone binding site [chemical binding]; other site
243265010937	C-subunit interface; other site
243265010938	distal quinone binding site; other site
243265010939	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265010940	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265010941	multidrug efflux system protein; Provisional; Region: PRK11431
243265010942	elongation factor P; Validated; Region: PRK00529
243265010943	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
243265010944	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
243265010945	RNA binding site [nucleotide binding]; other site
243265010946	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
243265010947	RNA binding site [nucleotide binding]; other site
243265010948	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
243265010949	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265010950	FeS/SAM binding site; other site
243265010951	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
243265010952	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265010953	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265010954	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
243265010955	dimerization interface [polypeptide binding]; other site
243265010956	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
243265010957	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
243265010958	ring oligomerisation interface [polypeptide binding]; other site
243265010959	ATP/Mg binding site [chemical binding]; other site
243265010960	stacking interactions; other site
243265010961	hinge regions; other site
243265010962	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
243265010963	oligomerisation interface [polypeptide binding]; other site
243265010964	mobile loop; other site
243265010965	roof hairpin; other site
243265010966	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
243265010967	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
243265010968	Aspartase; Region: Aspartase; cd01357
243265010969	active sites [active]
243265010970	tetramer interface [polypeptide binding]; other site
243265010971	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
243265010972	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
243265010973	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
243265010974	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
243265010975	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
243265010976	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
243265010977	DsbD alpha interface [polypeptide binding]; other site
243265010978	catalytic residues [active]
243265010979	putative transcriptional regulator; Provisional; Region: PRK11640
243265010980	CheD chemotactic sensory transduction; Region: CheD; cl00810
243265010981	TcdA/TcdB pore forming domain; Region: TcdA_TcdB_pore; pfam12920
243265010982	Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011
243265010983	active site
243265010984	metal binding site [ion binding]; metal-binding site
243265010985	Cupin-like domain; Region: Cupin_8; pfam13621
243265010986	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
243265010987	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265010988	Walker A/P-loop; other site
243265010989	ATP binding site [chemical binding]; other site
243265010990	Q-loop/lid; other site
243265010991	ABC transporter signature motif; other site
243265010992	Walker B; other site
243265010993	D-loop; other site
243265010994	H-loop/switch region; other site
243265010995	Truncated gene. Some similarities with Unknown protein of Photorhabdus luminescens
243265010996	Homeodomain-like domain; Region: HTH_23; pfam13384
243265010997	Winged helix-turn helix; Region: HTH_29; pfam13551
243265010998	Winged helix-turn helix; Region: HTH_33; pfam13592
243265010999	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265011000	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265011001	Truncated gene. Similar to N terminal region of Unknown protein of Photorhabdus luminescens
243265011002	Truncated gene. Similar to C terminal region of Unknown protein of Photorhabdus luminescens
243265011003	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
243265011004	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
243265011005	putative DNA binding site [nucleotide binding]; other site
243265011006	putative Zn2+ binding site [ion binding]; other site
243265011007	AsnC family; Region: AsnC_trans_reg; pfam01037
243265011008	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
243265011009	Truncated gene. Similar to the C-terminal region of histidine decarboxylase
243265011010	Transposase IS200 like; Region: Y1_Tnp; pfam01797
243265011011	Truncated gene. Similar to the N-terminal region of histidine decarboxylase
243265011012	Transposase IS200 like; Region: Y1_Tnp; pfam01797
243265011013	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
243265011014	Truncated gene. Highly similar to the N-terminal region of insecticidal toxin complex protein TccZ, disruption of the gene tccZ in TT01 genome compared to W14
243265011015	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
243265011016	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265011017	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
243265011018	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
243265011019	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
243265011020	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
243265011021	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
243265011022	Transposase; Region: HTH_Tnp_1; cl17663
243265011023	Truncated gene. Highly similar to the C-terminal region of insecticidal toxin complex protein TccZ, disruption of the gene tccZ in TT01 genome compared to W14
243265011024	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265011025	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265011026	Protein of unknown function (DUF3584); Region: DUF3584; pfam12128
243265011027	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
243265011028	PAAR motif; Region: PAAR_motif; pfam05488
243265011029	S-type Pyocin; Region: Pyocin_S; pfam06958
243265011030	Acetyltransferase (GNAT) domain; Region: Acetyltransf_4; pfam13420
243265011031	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265011032	Coenzyme A binding pocket [chemical binding]; other site
243265011033	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
243265011034	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265011035	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265011036	Acyl-CoA reductase LuxC; Region: ALDH_Acyl-CoA-Red_LuxC; cd07080
243265011037	Acyl-CoA reductase (LuxC); Region: LuxC; pfam05893
243265011038	putative catalytic cysteine [active]
243265011039	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265011040	active site
243265011041	AMP binding site [chemical binding]; other site
243265011042	acyl-activating enzyme (AAE) consensus motif; other site
243265011043	CoA binding site [chemical binding]; other site
243265011044	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
243265011045	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265011046	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265011047	YwqJ-like deaminase; Region: YwqJ-deaminase; pfam14431
243265011048	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
243265011049	Cytochrome P450; Region: p450; cl12078
243265011050	Predicted transcriptional regulator [Transcription]; Region: COG2378
243265011051	HTH domain; Region: HTH_11; pfam08279
243265011052	WYL domain; Region: WYL; cl14852
243265011053	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
243265011054	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
243265011055	hydrophobic ligand binding site; other site
243265011056	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
243265011057	hydrophobic ligand binding site; other site
243265011058	Polyketide cyclase / dehydrase and lipid transport; Region: Polyketide_cyc; pfam03364
243265011059	hydrophobic ligand binding site; other site
243265011060	AMP-binding enzyme; Region: AMP-binding; pfam00501
243265011061	Adenylate forming domain, Class I; Region: AFD_class_I; cd04433
243265011062	acyl-activating enzyme (AAE) consensus motif; other site
243265011063	AMP binding site [chemical binding]; other site
243265011064	active site
243265011065	CoA binding site [chemical binding]; other site
243265011066	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
243265011067	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
243265011068	active site
243265011069	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
243265011070	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
243265011071	dimer interface [polypeptide binding]; other site
243265011072	active site
243265011073	Putative cyclase; Region: Cyclase; pfam04199
243265011074	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
243265011075	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
243265011076	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
243265011077	NAD(P) binding site [chemical binding]; other site
243265011078	active site
243265011079	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011080	non-specific DNA binding site [nucleotide binding]; other site
243265011081	salt bridge; other site
243265011082	sequence-specific DNA binding site [nucleotide binding]; other site
243265011083	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
243265011084	BsuBI/PstI restriction endonuclease C-terminus; Region: BsuBI_PstI_RE; pfam06616
243265011085	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
243265011086	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
243265011087	ImpA domain protein; Region: DUF3702; pfam12486
243265011088	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
243265011089	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
243265011090	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
243265011091	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
243265011092	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
243265011093	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
243265011094	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
243265011095	chromosome segregation protein SMC, primarily archaeal type; Region: SMC_prok_A; TIGR02169
243265011096	Truncated gene. Similar to the C-terminal part of Unknown proteins of Photorhabdus luminescens
243265011097	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265011098	Truncated gene. Similar to the N terminal part of Unknown proteins of Photorhabdus luminescens
243265011099	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
243265011100	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
243265011101	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
243265011102	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
243265011103	PAAR motif; Region: PAAR_motif; pfam05488
243265011104	Domain of unknown function (DUF4123); Region: DUF4123; pfam13503
243265011105	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
243265011106	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265011107	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265011108	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
243265011109	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
243265011110	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
243265011111	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265011112	Walker A motif; other site
243265011113	ATP binding site [chemical binding]; other site
243265011114	Walker B motif; other site
243265011115	arginine finger; other site
243265011116	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265011117	Walker A motif; other site
243265011118	ATP binding site [chemical binding]; other site
243265011119	Walker B motif; other site
243265011120	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
243265011121	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
243265011122	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
243265011123	ligand binding site [chemical binding]; other site
243265011124	type IV / VI secretion system protein, DotU family; Region: IV_VI_DotU; TIGR03349
243265011125	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
243265011126	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
243265011127	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
243265011128	Protein of unknown function (DUF877); Region: DUF877; pfam05943
243265011129	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265011130	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265011131	putative substrate translocation pore; other site
243265011132	Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472
243265011133	Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; Region: HX; cl02471
243265011134	Metal binding sites [ion binding]; metal-binding site
243265011135	Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472
243265011136	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
243265011137	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265011138	Rhomboid family; Region: Rhomboid; cl11446
243265011139	Truncated gene. Some similarities with C-terminal region of truncated transposase, IS630 family
243265011140	C-terminal region of truncated transposase, IS630 family
243265011141	C-terminal region of truncated transposase, IS630 family
243265011142	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
243265011143	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
243265011144	Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472
243265011145	N-Terminal Domain Of Bc2l-C Lectin; Region: Bc2l-C_N; cd12211
243265011146	trimer interface [polypeptide binding]; other site
243265011147	ligand binding site [chemical binding]; other site
243265011148	Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; Region: HX; cl02471
243265011149	Metal binding sites [ion binding]; metal-binding site
243265011150	Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; Region: HX; cl02471
243265011151	Metal binding sites [ion binding]; metal-binding site
243265011152	Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472
243265011153	Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; Region: HX; cl02471
243265011154	Metal binding sites [ion binding]; metal-binding site
243265011155	Fucose-binding lectin II (PA-IIL); Region: PA-IIL; pfam07472
243265011156	Truncated transposase
243265011157	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
243265011158	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
243265011159	active site
243265011160	nucleophile elbow; other site
243265011161	periplasmic protein; Provisional; Region: PRK10568
243265011162	BON domain; Region: BON; pfam04972
243265011163	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
243265011164	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
243265011165	G1 box; other site
243265011166	putative GEF interaction site [polypeptide binding]; other site
243265011167	GTP/Mg2+ binding site [chemical binding]; other site
243265011168	Switch I region; other site
243265011169	G2 box; other site
243265011170	G3 box; other site
243265011171	Switch II region; other site
243265011172	G4 box; other site
243265011173	G5 box; other site
243265011174	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
243265011175	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
243265011176	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265011177	Coenzyme A binding pocket [chemical binding]; other site
243265011178	DNA polymerase III subunit psi; Validated; Region: PRK06856
243265011179	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
243265011180	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
243265011181	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265011182	S-adenosylmethionine binding site [chemical binding]; other site
243265011183	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265011184	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265011185	putative substrate translocation pore; other site
243265011186	alkaline phosphatase; Provisional; Region: PRK10518
243265011187	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
243265011188	dimer interface [polypeptide binding]; other site
243265011189	active site
243265011190	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
243265011191	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
243265011192	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
243265011193	Aromatic ring hydroxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2368
243265011194	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
243265011195	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
243265011196	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
243265011197	C-terminal domain interface [polypeptide binding]; other site
243265011198	GSH binding site (G-site) [chemical binding]; other site
243265011199	dimer interface [polypeptide binding]; other site
243265011200	C-terminal, alpha helical domain of Ure2p and related Glutathione S-transferase-like proteins; Region: GST_C_Ure2p_like; cd03178
243265011201	dimer interface [polypeptide binding]; other site
243265011202	N-terminal domain interface [polypeptide binding]; other site
243265011203	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
243265011204	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265011205	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
243265011206	dimerization interface [polypeptide binding]; other site
243265011207	substrate binding pocket [chemical binding]; other site
243265011208	luciferase-type oxidoreductase, BA3436 family; Region: lucif_BA3436; TIGR03571
243265011209	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
243265011210	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
243265011211	L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434
243265011212	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265011213	diaminobutyrate--2-oxoglutarate aminotransferase; Provisional; Region: PRK06938
243265011214	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265011215	inhibitor-cofactor binding pocket; inhibition site
243265011216	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265011217	catalytic residue [active]
243265011218	Cupin domain; Region: Cupin_2; pfam07883
243265011219	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
243265011220	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
243265011221	active site
243265011222	nucleotide binding site [chemical binding]; other site
243265011223	HIGH motif; other site
243265011224	KMSKS motif; other site
243265011225	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
243265011226	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265011227	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
243265011228	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
243265011229	ligand binding site [chemical binding]; other site
243265011230	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
243265011231	tyrosine decarboxylase MnfA; Region: tyr_de_CO2_Arch; TIGR03812
243265011232	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
243265011233	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265011234	catalytic residue [active]
243265011235	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
243265011236	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
243265011237	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
243265011238	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265011239	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265011240	DNA binding residues [nucleotide binding]
243265011241	dimerization interface [polypeptide binding]; other site
243265011242	Truncated gene. Some similarities with Rhs-family protein of Photorhabdus
243265011243	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265011244	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265011245	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265011246	PAAR motif; Region: PAAR_motif; pfam05488
243265011247	RHS Repeat; Region: RHS_repeat; cl11982
243265011248	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265011249	RHS Repeat; Region: RHS_repeat; cl11982
243265011250	RHS protein; Region: RHS; pfam03527
243265011251	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265011252	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
243265011253	Domain of unknown function (DUF1795); Region: DUF1795; pfam08786
243265011254	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
243265011255	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
243265011256	Fic family protein [Function unknown]; Region: COG3177
243265011257	Domain of unknown function (DUF4172); Region: DUF4172; pfam13776
243265011258	Fic/DOC family; Region: Fic; pfam02661
243265011259	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
243265011260	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
243265011261	NAD(P) binding site [chemical binding]; other site
243265011262	catalytic residues [active]
243265011263	Protein of unknown function (DUF861); Region: Cupin_3; cl17594
243265011264	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
243265011265	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
243265011266	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
243265011267	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265011268	DNA binding residues [nucleotide binding]
243265011269	dimerization interface [polypeptide binding]; other site
243265011270	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
243265011271	active site
243265011272	tetramer interface [polypeptide binding]; other site
243265011273	putative glycosyl transferase; Provisional; Region: PRK10073
243265011274	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
243265011275	active site
243265011276	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
243265011277	catalytic motif [active]
243265011278	Catalytic residue [active]
243265011279	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
243265011280	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265011281	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011282	non-specific DNA binding site [nucleotide binding]; other site
243265011283	salt bridge; other site
243265011284	sequence-specific DNA binding site [nucleotide binding]; other site
243265011285	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
243265011286	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
243265011287	CcdB protein; Region: CcdB; cl03380
243265011288	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
243265011289	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
243265011290	conserved cys residue [active]
243265011291	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
243265011292	Zn2+ binding site [ion binding]; other site
243265011293	Mg2+ binding site [ion binding]; other site
243265011294	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265011295	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011296	non-specific DNA binding site [nucleotide binding]; other site
243265011297	salt bridge; other site
243265011298	sequence-specific DNA binding site [nucleotide binding]; other site
243265011299	Transcriptional regulators [Transcription]; Region: GntR; COG1802
243265011300	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
243265011301	DNA-binding site [nucleotide binding]; DNA binding site
243265011302	FCD domain; Region: FCD; pfam07729
243265011303	Protein of unknown function (DUF969); Region: DUF969; pfam06149
243265011304	Predicted membrane protein [Function unknown]; Region: COG3817
243265011305	Protein of unknown function (DUF979); Region: DUF979; pfam06166
243265011306	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
243265011307	putative substrate binding pocket [chemical binding]; other site
243265011308	AC domain interface; other site
243265011309	catalytic triad [active]
243265011310	AB domain interface; other site
243265011311	interchain disulfide; other site
243265011312	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
243265011313	putative active site [active]
243265011314	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
243265011315	Allophanate hydrolase subunit 1; Region: AHS1; smart00796
243265011316	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
243265011317	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
243265011318	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
243265011319	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
243265011320	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
243265011321	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
243265011322	carboxyltransferase (CT) interaction site; other site
243265011323	biotinylation site [posttranslational modification]; other site
243265011324	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
243265011325	hypothetical protein; Reviewed; Region: PRK09588
243265011326	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
243265011327	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
243265011328	Protein of unknown function (DUF1190); Region: DUF1190; cl10031
243265011329	Predicted membrane protein [Function unknown]; Region: COG3766
243265011330	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
243265011331	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
243265011332	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
243265011333	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
243265011334	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
243265011335	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265011336	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265011337	S4 domain; Region: S4_2; cl17325
243265011338	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
243265011339	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
243265011340	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
243265011341	homodimer interface [polypeptide binding]; other site
243265011342	NADP binding site [chemical binding]; other site
243265011343	substrate binding site [chemical binding]; other site
243265011344	Truncated gene. Similar to the central region of integrase
243265011345	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
243265011346	HsdM N-terminal domain; Region: HsdM_N; pfam12161
243265011347	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265011348	S-adenosylmethionine binding site [chemical binding]; other site
243265011349	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
243265011350	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
243265011351	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
243265011352	AAA domain; Region: AAA_13; pfam13166
243265011353	AAA domain; Region: AAA_13; pfam13166
243265011354	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
243265011355	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
243265011356	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265011357	ATP binding site [chemical binding]; other site
243265011358	putative Mg++ binding site [ion binding]; other site
243265011359	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
243265011360	Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIR2-like; cd01406
243265011361	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
243265011362	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
243265011363	active site
243265011364	Protein of unknown function (DUF3732); Region: DUF3732; pfam12532
243265011365	Ribosomal protein S19; Region: Ribosomal_S19; cl00350
243265011366	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
243265011367	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
243265011368	substrate binding site [chemical binding]; other site
243265011369	catalytic Zn binding site [ion binding]; other site
243265011370	NAD binding site [chemical binding]; other site
243265011371	structural Zn binding site [ion binding]; other site
243265011372	dimer interface [polypeptide binding]; other site
243265011373	S-formylglutathione hydrolase; Region: PLN02442
243265011374	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
243265011375	Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3670
243265011376	Retinal pigment epithelial membrane protein; Region: RPE65; pfam03055
243265011377	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
243265011378	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
243265011379	substrate binding pocket [chemical binding]; other site
243265011380	substrate-Mg2+ binding site; other site
243265011381	aspartate-rich region 1; other site
243265011382	aspartate-rich region 2; other site
243265011383	Truncated gene. Similar to the N-terminal region of isopentenyl-diphosphate delta-isomerase
243265011384	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265011385	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265011386	Truncated gene. Similar to the C-terminal region of isopentenyl-diphosphate delta-isomerase
243265011387	Lycopene cyclase protein; Region: Lycopene_cycl; pfam05834
243265011388	lycopene cyclase; Region: lycopene_cycl; TIGR01789
243265011389	phytoene desaturase; Region: crtI_fam; TIGR02734
243265011390	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265011391	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
243265011392	active site lid residues [active]
243265011393	substrate binding pocket [chemical binding]; other site
243265011394	catalytic residues [active]
243265011395	substrate-Mg2+ binding site; other site
243265011396	aspartate-rich region 1; other site
243265011397	aspartate-rich region 2; other site
243265011398	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265011399	AAA domain; Region: AAA_23; pfam13476
243265011400	Walker A/P-loop; other site
243265011401	ATP binding site [chemical binding]; other site
243265011402	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265011403	Walker B; other site
243265011404	D-loop; other site
243265011405	H-loop/switch region; other site
243265011406	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
243265011407	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
243265011408	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
243265011409	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
243265011410	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
243265011411	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
243265011412	dimer interface [polypeptide binding]; other site
243265011413	ssDNA binding site [nucleotide binding]; other site
243265011414	tetramer (dimer of dimers) interface [polypeptide binding]; other site
243265011415	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
243265011416	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
243265011417	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
243265011418	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
243265011419	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
243265011420	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
243265011421	putative kinase; Provisional; Region: PRK09954
243265011422	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
243265011423	putative DNA binding site [nucleotide binding]; other site
243265011424	putative Zn2+ binding site [ion binding]; other site
243265011425	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
243265011426	substrate binding site [chemical binding]; other site
243265011427	ATP binding site [chemical binding]; other site
243265011428	YcfA-like protein; Region: YcfA; pfam07927
243265011429	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
243265011430	Cloacin immunity protein; Region: Cloacin_immun; pfam03513
243265011431	Homeodomain-like domain; Region: HTH_23; pfam13384
243265011432	Winged helix-turn helix; Region: HTH_29; pfam13551
243265011433	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265011434	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
243265011435	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
243265011436	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265011437	homodimer interface [polypeptide binding]; other site
243265011438	catalytic residue [active]
243265011439	alanine racemase; Reviewed; Region: alr; PRK00053
243265011440	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
243265011441	active site
243265011442	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
243265011443	substrate binding site [chemical binding]; other site
243265011444	catalytic residues [active]
243265011445	dimer interface [polypeptide binding]; other site
243265011446	replicative DNA helicase; Provisional; Region: PRK08006
243265011447	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
243265011448	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
243265011449	Walker A motif; other site
243265011450	ATP binding site [chemical binding]; other site
243265011451	Walker B motif; other site
243265011452	DNA binding loops [nucleotide binding]
243265011453	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
243265011454	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
243265011455	NADP binding site [chemical binding]; other site
243265011456	dimer interface [polypeptide binding]; other site
243265011457	Uncharacterized conserved protein [Function unknown]; Region: COG4933
243265011458	Homeodomain-like domain; Region: HTH_23; pfam13384
243265011459	Winged helix-turn helix; Region: HTH_29; pfam13551
243265011460	Winged helix-turn helix; Region: HTH_33; pfam13592
243265011461	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265011462	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265011463	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
243265011464	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
243265011465	FMN binding site [chemical binding]; other site
243265011466	active site
243265011467	catalytic residues [active]
243265011468	substrate binding site [chemical binding]; other site
243265011469	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011470	non-specific DNA binding site [nucleotide binding]; other site
243265011471	salt bridge; other site
243265011472	sequence-specific DNA binding site [nucleotide binding]; other site
243265011473	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
243265011474	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011475	non-specific DNA binding site [nucleotide binding]; other site
243265011476	salt bridge; other site
243265011477	sequence-specific DNA binding site [nucleotide binding]; other site
243265011478	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
243265011479	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
243265011480	active site
243265011481	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
243265011482	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
243265011483	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
243265011484	teramer interface [polypeptide binding]; other site
243265011485	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
243265011486	active site
243265011487	FMN binding site [chemical binding]; other site
243265011488	catalytic residues [active]
243265011489	hypothetical protein; Provisional; Region: PRK11380
243265011490	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
243265011491	metal binding site 2 [ion binding]; metal-binding site
243265011492	putative DNA binding helix; other site
243265011493	metal binding site 1 [ion binding]; metal-binding site
243265011494	dimer interface [polypeptide binding]; other site
243265011495	structural Zn2+ binding site [ion binding]; other site
243265011496	LexA repressor; Validated; Region: PRK00215
243265011497	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
243265011498	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
243265011499	Catalytic site [active]
243265011500	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
243265011501	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
243265011502	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
243265011503	putative acyl-acceptor binding pocket; other site
243265011504	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
243265011505	UbiA prenyltransferase family; Region: UbiA; pfam01040
243265011506	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
243265011507	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
243265011508	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
243265011509	active site
243265011510	dimer interface [polypeptide binding]; other site
243265011511	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
243265011512	dimer interface [polypeptide binding]; other site
243265011513	active site
243265011514	aspartate kinase III; Validated; Region: PRK09084
243265011515	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
243265011516	nucleotide binding site [chemical binding]; other site
243265011517	substrate binding site [chemical binding]; other site
243265011518	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
243265011519	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
243265011520	dimer interface [polypeptide binding]; other site
243265011521	Phosphopantetheine attachment site; Region: PP-binding; cl09936
243265011522	D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092
243265011523	DltD C-terminal region; Region: DltD_C; pfam04914
243265011524	MBOAT, membrane-bound O-acyltransferase family; Region: MBOAT; cl00738
243265011525	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
243265011526	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
243265011527	acyl-activating enzyme (AAE) consensus motif; other site
243265011528	AMP binding site [chemical binding]; other site
243265011529	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
243265011530	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
243265011531	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
243265011532	inhibitor-cofactor binding pocket; inhibition site
243265011533	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265011534	catalytic residue [active]
243265011535	Predicted dehydrogenase [General function prediction only]; Region: COG5322
243265011536	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
243265011537	NAD(P) binding pocket [chemical binding]; other site
243265011538	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
243265011539	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
243265011540	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
243265011541	nucleophilic elbow; other site
243265011542	catalytic triad; other site
243265011543	M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1; Region: M28_Fxna_like; cd03875
243265011544	Peptidase family M28; Region: Peptidase_M28; pfam04389
243265011545	metal binding site [ion binding]; metal-binding site
243265011546	transcriptional repressor IclR; Provisional; Region: PRK11569
243265011547	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
243265011548	Bacterial transcriptional regulator; Region: IclR; pfam01614
243265011549	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
243265011550	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
243265011551	isocitrate lyase; Provisional; Region: PRK15063
243265011552	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
243265011553	tetramer interface [polypeptide binding]; other site
243265011554	active site
243265011555	Mg2+/Mn2+ binding site [ion binding]; other site
243265011556	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
243265011557	malate synthase A; Region: malate_syn_A; TIGR01344
243265011558	active site
243265011559	homoserine O-succinyltransferase; Provisional; Region: PRK05368
243265011560	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
243265011561	proposed active site lysine [active]
243265011562	conserved cys residue [active]
243265011563	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
243265011564	potassium transporter; Provisional; Region: PRK10750
243265011565	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
243265011566	hypothetical protein; Provisional; Region: PRK11568
243265011567	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
243265011568	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
243265011569	proline dipeptidase; Provisional; Region: PRK13607
243265011570	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
243265011571	active site
243265011572	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
243265011573	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
243265011574	substrate binding site [chemical binding]; other site
243265011575	oxyanion hole (OAH) forming residues; other site
243265011576	trimer interface [polypeptide binding]; other site
243265011577	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
243265011578	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
243265011579	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
243265011580	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
243265011581	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
243265011582	dimer interface [polypeptide binding]; other site
243265011583	active site
243265011584	FMN reductase; Validated; Region: fre; PRK08051
243265011585	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
243265011586	FAD binding pocket [chemical binding]; other site
243265011587	FAD binding motif [chemical binding]; other site
243265011588	phosphate binding motif [ion binding]; other site
243265011589	beta-alpha-beta structure motif; other site
243265011590	NAD binding pocket [chemical binding]; other site
243265011591	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
243265011592	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
243265011593	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
243265011594	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
243265011595	dimer interface [polypeptide binding]; other site
243265011596	allosteric magnesium binding site [ion binding]; other site
243265011597	active site
243265011598	aspartate-rich active site metal binding site; other site
243265011599	Schiff base residues; other site
243265011600	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
243265011601	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
243265011602	twin arginine translocase protein A; Provisional; Region: tatA; PRK04598
243265011603	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
243265011604	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
243265011605	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
243265011606	SCP-2 sterol transfer family; Region: SCP2; pfam02036
243265011607	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
243265011608	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265011609	S-adenosylmethionine binding site [chemical binding]; other site
243265011610	RmuC family; Region: RmuC; pfam02646
243265011611	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
243265011612	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
243265011613	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
243265011614	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
243265011615	uridine phosphorylase; Provisional; Region: PRK11178
243265011616	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
243265011617	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
243265011618	putative substrate binding pocket [chemical binding]; other site
243265011619	AC domain interface; other site
243265011620	catalytic triad [active]
243265011621	AB domain interface; other site
243265011622	interchain disulfide; other site
243265011623	TAT (twin-arginine translocation) pathway signal sequence; Region: TAT_signal; pfam10518
243265011624	Intradiol dioxygenase supgroup. Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. They break the catechol C1-C2 bond and utilize Fe3+, as opposed to  the...; Region: intradiol_dioxygenase_like; cd03457
243265011625	putative active site [active]
243265011626	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
243265011627	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
243265011628	THF binding site; other site
243265011629	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
243265011630	substrate binding site [chemical binding]; other site
243265011631	THF binding site; other site
243265011632	zinc-binding site [ion binding]; other site
243265011633	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
243265011634	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265011635	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
243265011636	putative dimerization interface [polypeptide binding]; other site
243265011637	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
243265011638	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
243265011639	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
243265011640	Major Facilitator Superfamily; Region: MFS_1; pfam07690
243265011641	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265011642	putative substrate translocation pore; other site
243265011643	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
243265011644	Truncated gene. Highly similar to the N-terminal region of transposase
243265011645	Truncated gene. Highly similar to the central region of transposase
243265011646	Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480
243265011647	Truncated gene. Similar to central part of RetA protein
243265011648	Truncated gene. Some similarities with N-terminal part of RetA protein
243265011649	Homeodomain-like domain; Region: HTH_23; pfam13384
243265011650	Winged helix-turn helix; Region: HTH_29; pfam13551
243265011651	Winged helix-turn helix; Region: HTH_33; pfam13592
243265011652	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265011653	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265011654	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
243265011655	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
243265011656	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
243265011657	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
243265011658	DNA binding site [nucleotide binding]
243265011659	Homeodomain-like domain; Region: HTH_23; pfam13384
243265011660	Winged helix-turn helix; Region: HTH_29; pfam13551
243265011661	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265011662	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265011663	Truncated transposase, IS30 family (ISPlu1-p)
243265011664	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
243265011665	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
243265011666	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
243265011667	DNA binding residues [nucleotide binding]
243265011668	fec operon regulator FecR; Reviewed; Region: PRK09774
243265011669	FecR protein; Region: FecR; pfam04773
243265011670	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
243265011671	Secretin and TonB N terminus short domain; Region: STN; smart00965
243265011672	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265011673	N-terminal plug; other site
243265011674	ligand-binding site [chemical binding]; other site
243265011675	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
243265011676	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
243265011677	siderophore binding site; other site
243265011678	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
243265011679	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265011680	ABC-ATPase subunit  interface; other site
243265011681	dimer interface [polypeptide binding]; other site
243265011682	putative PBP binding regions; other site
243265011683	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
243265011684	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265011685	ABC-ATPase subunit  interface; other site
243265011686	dimer interface [polypeptide binding]; other site
243265011687	putative PBP binding regions; other site
243265011688	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
243265011689	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
243265011690	Walker A/P-loop; other site
243265011691	ATP binding site [chemical binding]; other site
243265011692	Q-loop/lid; other site
243265011693	ABC transporter signature motif; other site
243265011694	Walker B; other site
243265011695	D-loop; other site
243265011696	H-loop/switch region; other site
243265011697	Part of AAA domain; Region: AAA_19; pfam13245
243265011698	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
243265011699	AAA domain; Region: AAA_12; pfam13087
243265011700	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
243265011701	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265011702	ATP binding site [chemical binding]; other site
243265011703	putative Mg++ binding site [ion binding]; other site
243265011704	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265011705	nucleotide binding region [chemical binding]; other site
243265011706	ATP-binding site [chemical binding]; other site
243265011707	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265011708	active site
243265011709	DNA protecting protein DprA; Region: dprA; TIGR00732
243265011710	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
243265011711	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
243265011712	Truncated transposase, IS630 family (ISPlu8-p)
243265011713	Truncated gene. Some similarities with the N-terminal region of Unknown protein.
243265011714	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265011715	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
243265011716	Walker A motif; other site
243265011717	ATP binding site [chemical binding]; other site
243265011718	Walker B motif; other site
243265011719	arginine finger; other site
243265011720	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
243265011721	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
243265011722	active site
243265011723	catalytic triad [active]
243265011724	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
243265011725	integrase; Provisional; Region: PRK09692
243265011726	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
243265011727	active site
243265011728	Int/Topo IB signature motif; other site
243265011729	Predicted transcriptional regulator [Transcription]; Region: COG2944
243265011730	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011731	non-specific DNA binding site [nucleotide binding]; other site
243265011732	salt bridge; other site
243265011733	sequence-specific DNA binding site [nucleotide binding]; other site
243265011734	Protein of unknown function (DUF1044); Region: DUF1044; pfam06296
243265011735	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
243265011736	Integrase; Region: Integrase_1; pfam12835
243265011737	AAA domain; Region: AAA_25; pfam13481
243265011738	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
243265011739	Walker A motif; other site
243265011740	ATP binding site [chemical binding]; other site
243265011741	Walker B motif; other site
243265011742	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265011743	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011744	non-specific DNA binding site [nucleotide binding]; other site
243265011745	salt bridge; other site
243265011746	sequence-specific DNA binding site [nucleotide binding]; other site
243265011747	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
243265011748	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
243265011749	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
243265011750	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011751	non-specific DNA binding site [nucleotide binding]; other site
243265011752	salt bridge; other site
243265011753	sequence-specific DNA binding site [nucleotide binding]; other site
243265011754	integrase; Provisional; Region: PRK09692
243265011755	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
243265011756	active site
243265011757	Int/Topo IB signature motif; other site
243265011758	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
243265011759	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
243265011760	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
243265011761	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
243265011762	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
243265011763	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
243265011764	multifunctional aminopeptidase A; Provisional; Region: PRK00913
243265011765	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
243265011766	interface (dimer of trimers) [polypeptide binding]; other site
243265011767	Substrate-binding/catalytic site; other site
243265011768	Zn-binding sites [ion binding]; other site
243265011769	DNA polymerase III subunit chi; Validated; Region: PRK05728
243265011770	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
243265011771	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
243265011772	HIGH motif; other site
243265011773	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
243265011774	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
243265011775	active site
243265011776	KMSKS motif; other site
243265011777	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
243265011778	tRNA binding surface [nucleotide binding]; other site
243265011779	anticodon binding site; other site
243265011780	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
243265011781	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
243265011782	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265011783	substrate binding pocket [chemical binding]; other site
243265011784	membrane-bound complex binding site; other site
243265011785	hinge residues; other site
243265011786	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
243265011787	dimer interface [polypeptide binding]; other site
243265011788	conserved gate region; other site
243265011789	putative PBP binding loops; other site
243265011790	ABC-ATPase subunit interface; other site
243265011791	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
243265011792	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
243265011793	Walker A/P-loop; other site
243265011794	ATP binding site [chemical binding]; other site
243265011795	Q-loop/lid; other site
243265011796	ABC transporter signature motif; other site
243265011797	Walker B; other site
243265011798	D-loop; other site
243265011799	H-loop/switch region; other site
243265011800	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
243265011801	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
243265011802	substrate binding pocket [chemical binding]; other site
243265011803	membrane-bound complex binding site; other site
243265011804	hinge residues; other site
243265011805	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
243265011806	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
243265011807	RNase E inhibitor protein; Provisional; Region: PRK11191
243265011808	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
243265011809	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
243265011810	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
243265011811	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
243265011812	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
243265011813	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
243265011814	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
243265011815	Transposase Tn5 dimerisation domain; Region: Dimer_Tnp_Tn5; pfam02281
243265011816	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
243265011817	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
243265011818	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
243265011819	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
243265011820	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
243265011821	homotrimer interaction site [polypeptide binding]; other site
243265011822	putative active site [active]
243265011823	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
243265011824	ATP cone domain; Region: ATP-cone; pfam03477
243265011825	Class III ribonucleotide reductase; Region: RNR_III; cd01675
243265011826	effector binding site; other site
243265011827	active site
243265011828	Zn binding site [ion binding]; other site
243265011829	glycine loop; other site
243265011830	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
243265011831	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
243265011832	FeS/SAM binding site; other site
243265011833	hypothetical protein; Provisional; Region: PRK03467
243265011834	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
243265011835	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
243265011836	GIY-YIG motif/motif A; other site
243265011837	putative active site [active]
243265011838	putative metal binding site [ion binding]; other site
243265011839	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
243265011840	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265011841	Coenzyme A binding pocket [chemical binding]; other site
243265011842	SCP-2 sterol transfer family; Region: SCP2; cl01225
243265011843	prenyltransferase; Reviewed; Region: ubiA; PRK05951
243265011844	UbiA prenyltransferase family; Region: UbiA; pfam01040
243265011845	Class I hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classI; cd00643
243265011846	tetramerization interface [polypeptide binding]; other site
243265011847	substrate binding pocket [chemical binding]; other site
243265011848	catalytic residues [active]
243265011849	inhibitor binding sites; inhibition site
243265011850	NADP(H) binding site [chemical binding]; other site
243265011851	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
243265011852	Phosphotransferase enzyme family; Region: APH; pfam01636
243265011853	substrate binding site [chemical binding]; other site
243265011854	phosphoenolpyruvate synthase; Validated; Region: PRK06241
243265011855	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
243265011856	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
243265011857	peptide synthase; Provisional; Region: PRK09274
243265011858	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
243265011859	acyl-activating enzyme (AAE) consensus motif; other site
243265011860	AMP binding site [chemical binding]; other site
243265011861	active site
243265011862	CoA binding site [chemical binding]; other site
243265011863	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
243265011864	Putative integral membrane protein DUF46; Region: DUF46; cl17511
243265011865	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265011866	salt bridge; other site
243265011867	non-specific DNA binding site [nucleotide binding]; other site
243265011868	sequence-specific DNA binding site [nucleotide binding]; other site
243265011869	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
243265011870	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
243265011871	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
243265011872	ABC-2 type transporter; Region: ABC2_membrane; cl17235
243265011873	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265011874	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265011875	Highly similar to the N-terminal region of Unknown protein.
243265011876	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265011877	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
243265011878	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
243265011879	Highly similar to the C-terminal region of Unknown protein.
243265011880	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
243265011881	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265011882	active site
243265011883	phosphorylation site [posttranslational modification]
243265011884	intermolecular recognition site; other site
243265011885	dimerization interface [polypeptide binding]; other site
243265011886	LytTr DNA-binding domain; Region: LytTR; pfam04397
243265011887	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
243265011888	Carbon starvation protein CstA; Region: CstA; pfam02554
243265011889	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
243265011890	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
243265011891	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
243265011892	ATP binding site [chemical binding]; other site
243265011893	Mg++ binding site [ion binding]; other site
243265011894	motif III; other site
243265011895	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265011896	nucleotide binding region [chemical binding]; other site
243265011897	ATP-binding site [chemical binding]; other site
243265011898	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
243265011899	putative RNA binding site [nucleotide binding]; other site
243265011900	lipoprotein NlpI; Provisional; Region: PRK11189
243265011901	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
243265011902	binding surface
243265011903	TPR motif; other site
243265011904	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
243265011905	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
243265011906	RNase E interface [polypeptide binding]; other site
243265011907	trimer interface [polypeptide binding]; other site
243265011908	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
243265011909	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
243265011910	RNase E interface [polypeptide binding]; other site
243265011911	trimer interface [polypeptide binding]; other site
243265011912	active site
243265011913	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
243265011914	putative nucleic acid binding region [nucleotide binding]; other site
243265011915	G-X-X-G motif; other site
243265011916	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
243265011917	RNA binding site [nucleotide binding]; other site
243265011918	domain interface; other site
243265011919	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
243265011920	16S/18S rRNA binding site [nucleotide binding]; other site
243265011921	S13e-L30e interaction site [polypeptide binding]; other site
243265011922	25S rRNA binding site [nucleotide binding]; other site
243265011923	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
243265011924	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
243265011925	RNA binding site [nucleotide binding]; other site
243265011926	active site
243265011927	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
243265011928	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
243265011929	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
243265011930	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
243265011931	translation initiation factor IF-2; Region: IF-2; TIGR00487
243265011932	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
243265011933	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
243265011934	G1 box; other site
243265011935	putative GEF interaction site [polypeptide binding]; other site
243265011936	GTP/Mg2+ binding site [chemical binding]; other site
243265011937	Switch I region; other site
243265011938	G2 box; other site
243265011939	G3 box; other site
243265011940	Switch II region; other site
243265011941	G4 box; other site
243265011942	G5 box; other site
243265011943	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
243265011944	Translation-initiation factor 2; Region: IF-2; pfam11987
243265011945	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
243265011946	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
243265011947	NusA N-terminal domain; Region: NusA_N; pfam08529
243265011948	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
243265011949	RNA binding site [nucleotide binding]; other site
243265011950	homodimer interface [polypeptide binding]; other site
243265011951	NusA-like KH domain; Region: KH_5; pfam13184
243265011952	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
243265011953	G-X-X-G motif; other site
243265011954	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
243265011955	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
243265011956	ribosome maturation protein RimP; Reviewed; Region: PRK00092
243265011957	Sm and related proteins; Region: Sm_like; cl00259
243265011958	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
243265011959	putative oligomer interface [polypeptide binding]; other site
243265011960	putative RNA binding site [nucleotide binding]; other site
243265011961	Preprotein translocase SecG subunit; Region: SecG; pfam03840
243265011962	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
243265011963	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
243265011964	active site
243265011965	substrate binding site [chemical binding]; other site
243265011966	metal binding site [ion binding]; metal-binding site
243265011967	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
243265011968	dihydropteroate synthase; Region: DHPS; TIGR01496
243265011969	substrate binding pocket [chemical binding]; other site
243265011970	dimer interface [polypeptide binding]; other site
243265011971	inhibitor binding site; inhibition site
243265011972	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
243265011973	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265011974	Walker A motif; other site
243265011975	ATP binding site [chemical binding]; other site
243265011976	Walker B motif; other site
243265011977	arginine finger; other site
243265011978	Peptidase family M41; Region: Peptidase_M41; pfam01434
243265011979	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
243265011980	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265011981	S-adenosylmethionine binding site [chemical binding]; other site
243265011982	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; cl00663
243265011983	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
243265011984	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
243265011985	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
243265011986	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
243265011987	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
243265011988	GTPase CgtA; Reviewed; Region: obgE; PRK12298
243265011989	GTP1/OBG; Region: GTP1_OBG; pfam01018
243265011990	Obg GTPase; Region: Obg; cd01898
243265011991	G1 box; other site
243265011992	GTP/Mg2+ binding site [chemical binding]; other site
243265011993	Switch I region; other site
243265011994	G2 box; other site
243265011995	G3 box; other site
243265011996	Switch II region; other site
243265011997	G4 box; other site
243265011998	G5 box; other site
243265011999	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
243265012000	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
243265012001	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
243265012002	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
243265012003	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
243265012004	substrate binding pocket [chemical binding]; other site
243265012005	chain length determination region; other site
243265012006	substrate-Mg2+ binding site; other site
243265012007	catalytic residues [active]
243265012008	aspartate-rich region 1; other site
243265012009	active site lid residues [active]
243265012010	aspartate-rich region 2; other site
243265012011	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
243265012012	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
243265012013	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
243265012014	malate dehydrogenase; Provisional; Region: PRK05086
243265012015	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
243265012016	NAD binding site [chemical binding]; other site
243265012017	dimerization interface [polypeptide binding]; other site
243265012018	Substrate binding site [chemical binding]; other site
243265012019	arginine repressor; Provisional; Region: PRK05066
243265012020	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
243265012021	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
243265012022	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
243265012023	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
243265012024	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
243265012025	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
243265012026	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
243265012027	AMP binding site [chemical binding]; other site
243265012028	metal binding site [ion binding]; metal-binding site
243265012029	active site
243265012030	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
243265012031	dimer interface [polypeptide binding]; other site
243265012032	substrate binding site [chemical binding]; other site
243265012033	metal binding sites [ion binding]; metal-binding site
243265012034	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
243265012035	putative active site pocket [active]
243265012036	dimerization interface [polypeptide binding]; other site
243265012037	putative catalytic residue [active]
243265012038	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
243265012039	Family of unknown function (DUF490); Region: DUF490; pfam04357
243265012040	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
243265012041	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
243265012042	Surface antigen; Region: Bac_surface_Ag; pfam01103
243265012043	methionine sulfoxide reductase A; Provisional; Region: PRK00058
243265012044	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
243265012045	Domain of unknown function DUF21; Region: DUF21; pfam01595
243265012046	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
243265012047	Transporter associated domain; Region: CorC_HlyC; smart01091
243265012048	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
243265012049	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
243265012050	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
243265012051	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
243265012052	active site
243265012053	Homeodomain-like domain; Region: HTH_23; pfam13384
243265012054	Winged helix-turn helix; Region: HTH_29; pfam13551
243265012055	Winged helix-turn helix; Region: HTH_33; pfam13592
243265012056	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265012057	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265012058	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
243265012059	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
243265012060	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
243265012061	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
243265012062	DNA binding residues [nucleotide binding]
243265012063	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
243265012064	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265012065	H+ Antiporter protein; Region: 2A0121; TIGR00900
243265012066	putative substrate translocation pore; other site
243265012067	Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192
243265012068	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
243265012069	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
243265012070	Amidinotransferase; Region: Amidinotransf; cl12043
243265012071	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
243265012072	argininosuccinate synthase; Provisional; Region: PRK13820
243265012073	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
243265012074	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
243265012075	dimer interface [polypeptide binding]; other site
243265012076	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012077	catalytic residue [active]
243265012078	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
243265012079	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
243265012080	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
243265012081	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
243265012082	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
243265012083	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
243265012084	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
243265012085	dimer interface [polypeptide binding]; other site
243265012086	ssDNA binding site [nucleotide binding]; other site
243265012087	tetramer (dimer of dimers) interface [polypeptide binding]; other site
243265012088	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
243265012089	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
243265012090	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
243265012091	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
243265012092	exoribonuclease R; Provisional; Region: PRK11642
243265012093	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
243265012094	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
243265012095	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
243265012096	RNB domain; Region: RNB; pfam00773
243265012097	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
243265012098	RNA binding site [nucleotide binding]; other site
243265012099	transcriptional repressor NsrR; Provisional; Region: PRK11014
243265012100	Predicted transcriptional regulator [Transcription]; Region: COG1959
243265012101	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
243265012102	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
243265012103	GDP-binding site [chemical binding]; other site
243265012104	ACT binding site; other site
243265012105	IMP binding site; other site
243265012106	FtsH protease regulator HflC; Provisional; Region: PRK11029
243265012107	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
243265012108	FtsH protease regulator HflK; Provisional; Region: PRK10930
243265012109	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
243265012110	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
243265012111	GTPase HflX; Provisional; Region: PRK11058
243265012112	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
243265012113	HflX GTPase family; Region: HflX; cd01878
243265012114	G1 box; other site
243265012115	GTP/Mg2+ binding site [chemical binding]; other site
243265012116	Switch I region; other site
243265012117	G2 box; other site
243265012118	G3 box; other site
243265012119	Switch II region; other site
243265012120	G4 box; other site
243265012121	G5 box; other site
243265012122	bacterial Hfq-like; Region: Hfq; cd01716
243265012123	hexamer interface [polypeptide binding]; other site
243265012124	Sm1 motif; other site
243265012125	RNA binding site [nucleotide binding]; other site
243265012126	Sm2 motif; other site
243265012127	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
243265012128	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
243265012129	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
243265012130	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265012131	ATP binding site [chemical binding]; other site
243265012132	Mg2+ binding site [ion binding]; other site
243265012133	G-X-G motif; other site
243265012134	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
243265012135	ATP binding site [chemical binding]; other site
243265012136	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
243265012137	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
243265012138	AMIN domain; Region: AMIN; pfam11741
243265012139	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
243265012140	active site
243265012141	metal binding site [ion binding]; metal-binding site
243265012142	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
243265012143	epoxyqueuosine reductase; Region: TIGR00276
243265012144	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
243265012145	Transcriptional regulator [Transcription]; Region: LysR; COG0583
243265012146	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265012147	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
243265012148	dimerization interface [polypeptide binding]; other site
243265012149	StaR_like; a well-conserved protein found in bacteria, plants, and animals. A family member from Streptomyces toyocaensis, StaR is part of a gene cluster involved in the biosynthesis of glycopeptide antibiotics (GPAs), specifically A47934. It has been...; Region: StaR_like; cd05804
243265012150	EamA-like transporter family; Region: EamA; pfam00892
243265012151	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
243265012152	EamA-like transporter family; Region: EamA; pfam00892
243265012153	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265012154	non-specific DNA binding site [nucleotide binding]; other site
243265012155	salt bridge; other site
243265012156	sequence-specific DNA binding site [nucleotide binding]; other site
243265012157	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
243265012158	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
243265012159	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
243265012160	catalytic site [active]
243265012161	putative active site [active]
243265012162	putative substrate binding site [chemical binding]; other site
243265012163	dimer interface [polypeptide binding]; other site
243265012164	GTPase RsgA; Reviewed; Region: PRK12288
243265012165	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
243265012166	RNA binding site [nucleotide binding]; other site
243265012167	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
243265012168	GTPase/Zn-binding domain interface [polypeptide binding]; other site
243265012169	GTP/Mg2+ binding site [chemical binding]; other site
243265012170	G4 box; other site
243265012171	G5 box; other site
243265012172	G1 box; other site
243265012173	Switch I region; other site
243265012174	G2 box; other site
243265012175	G3 box; other site
243265012176	Switch II region; other site
243265012177	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
243265012178	putative mechanosensitive channel protein; Provisional; Region: PRK10929
243265012179	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
243265012180	Mechanosensitive ion channel; Region: MS_channel; pfam00924
243265012181	PAAR motif; Region: PAAR_motif; pfam05488
243265012182	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
243265012183	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
243265012184	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
243265012185	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
243265012186	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
243265012187	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733
243265012188	Domain of unknown function (DUF4123); Region: DUF4123; pfam13503
243265012189	acetylornithine deacetylase; Validated; Region: PRK06915
243265012190	PAAR motif; Region: PAAR_motif; pfam05488
243265012191	PAAR motif; Region: PAAR_motif; pfam05488
243265012192	C-terminal region of truncated transposase, IS4 family
243265012193	N-terminal region of truncated transposase, IS4 family
243265012194	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
243265012195	putative catalytic site [active]
243265012196	putative metal binding site [ion binding]; other site
243265012197	putative phosphate binding site [ion binding]; other site
243265012198	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
243265012199	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
243265012200	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
243265012201	Transposase IS200 like; Region: Y1_Tnp; pfam01797
243265012202	putative hydrolase; Provisional; Region: PRK10976
243265012203	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265012204	active site
243265012205	motif I; other site
243265012206	motif II; other site
243265012207	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265012208	lysophospholipase L2; Provisional; Region: PRK10749
243265012209	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
243265012210	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
243265012211	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265012212	ATP binding site [chemical binding]; other site
243265012213	putative Mg++ binding site [ion binding]; other site
243265012214	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265012215	nucleotide binding region [chemical binding]; other site
243265012216	ATP-binding site [chemical binding]; other site
243265012217	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
243265012218	HRDC domain; Region: HRDC; pfam00570
243265012219	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
243265012220	IucA / IucC family; Region: IucA_IucC; pfam04183
243265012221	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
243265012222	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773
243265012223	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265012224	N-terminal plug; other site
243265012225	ligand-binding site [chemical binding]; other site
243265012226	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
243265012227	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
243265012228	siderophore binding site; other site
243265012229	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
243265012230	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265012231	ABC-ATPase subunit  interface; other site
243265012232	dimer interface [polypeptide binding]; other site
243265012233	putative PBP binding regions; other site
243265012234	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
243265012235	ABC-ATPase subunit  interface; other site
243265012236	dimer interface [polypeptide binding]; other site
243265012237	putative PBP binding regions; other site
243265012238	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
243265012239	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
243265012240	Walker A/P-loop; other site
243265012241	ATP binding site [chemical binding]; other site
243265012242	Q-loop/lid; other site
243265012243	ABC transporter signature motif; other site
243265012244	Walker B; other site
243265012245	D-loop; other site
243265012246	H-loop/switch region; other site
243265012247	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
243265012248	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
243265012249	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
243265012250	tyrosine decarboxylase; Region: PLN02880
243265012251	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
243265012252	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012253	catalytic residue [active]
243265012254	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
243265012255	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265012256	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265012257	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
243265012258	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
243265012259	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
243265012260	IucA / IucC family; Region: IucA_IucC; pfam04183
243265012261	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
243265012262	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
243265012263	CoenzymeA binding site [chemical binding]; other site
243265012264	subunit interaction site [polypeptide binding]; other site
243265012265	PHB binding site; other site
243265012266	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
243265012267	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265012268	Coenzyme A binding pocket [chemical binding]; other site
243265012269	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
243265012270	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
243265012271	Cl binding site [ion binding]; other site
243265012272	oligomer interface [polypeptide binding]; other site
243265012273	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
243265012274	Part of AAA domain; Region: AAA_19; pfam13245
243265012275	Family description; Region: UvrD_C_2; pfam13538
243265012276	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
243265012277	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265012278	motif II; other site
243265012279	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
243265012280	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
243265012281	active site
243265012282	DNA binding site [nucleotide binding]
243265012283	Int/Topo IB signature motif; other site
243265012284	hypothetical protein; Provisional; Region: PRK10963
243265012285	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
243265012286	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
243265012287	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
243265012288	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; cl02361
243265012289	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
243265012290	putative iron binding site [ion binding]; other site
243265012291	adenylate cyclase; Provisional; Region: cyaA; PRK09450
243265012292	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
243265012293	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
243265012294	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
243265012295	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
243265012296	domain interfaces; other site
243265012297	active site
243265012298	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
243265012299	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
243265012300	active site
243265012301	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
243265012302	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
243265012303	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
243265012304	HemY protein N-terminus; Region: HemY_N; pfam07219
243265012305	Predicted membrane protein [Function unknown]; Region: XynA; COG2314
243265012306	Domain of unknown function (DUF4277); Region: DUF4277; pfam14104
243265012307	Transposase [DNA replication, recombination, and repair]; Region: COG5421
243265012308	putative transport protein YifK; Provisional; Region: PRK10746
243265012309	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
243265012310	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
243265012311	putative common antigen polymerase; Provisional; Region: PRK02975
243265012312	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
243265012313	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
243265012314	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
243265012315	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
243265012316	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
243265012317	inhibitor-cofactor binding pocket; inhibition site
243265012318	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012319	catalytic residue [active]
243265012320	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
243265012321	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
243265012322	Coenzyme A binding pocket [chemical binding]; other site
243265012323	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
243265012324	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
243265012325	substrate binding site; other site
243265012326	tetramer interface; other site
243265012327	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
243265012328	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
243265012329	NAD binding site [chemical binding]; other site
243265012330	substrate binding site [chemical binding]; other site
243265012331	homodimer interface [polypeptide binding]; other site
243265012332	active site
243265012333	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
243265012334	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
243265012335	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
243265012336	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
243265012337	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
243265012338	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
243265012339	active site
243265012340	homodimer interface [polypeptide binding]; other site
243265012341	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
243265012342	Chain length determinant protein; Region: Wzz; pfam02706
243265012343	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
243265012344	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
243265012345	Mg++ binding site [ion binding]; other site
243265012346	putative catalytic motif [active]
243265012347	substrate binding site [chemical binding]; other site
243265012348	transcription termination factor Rho; Provisional; Region: rho; PRK09376
243265012349	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
243265012350	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
243265012351	RNA binding site [nucleotide binding]; other site
243265012352	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
243265012353	multimer interface [polypeptide binding]; other site
243265012354	Walker A motif; other site
243265012355	ATP binding site [chemical binding]; other site
243265012356	Walker B motif; other site
243265012357	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
243265012358	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
243265012359	catalytic residues [active]
243265012360	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
243265012361	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
243265012362	ATP binding site [chemical binding]; other site
243265012363	Mg++ binding site [ion binding]; other site
243265012364	motif III; other site
243265012365	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
243265012366	nucleotide binding region [chemical binding]; other site
243265012367	ATP-binding site [chemical binding]; other site
243265012368	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
243265012369	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
243265012370	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
243265012371	Part of AAA domain; Region: AAA_19; pfam13245
243265012372	Family description; Region: UvrD_C_2; pfam13538
243265012373	ketol-acid reductoisomerase; Validated; Region: PRK05225
243265012374	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
243265012375	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
243265012376	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
243265012377	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265012378	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
243265012379	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
243265012380	putative dimerization interface [polypeptide binding]; other site
243265012381	Helix-turn-helix domain; Region: HTH_18; pfam12833
243265012382	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
243265012383	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
243265012384	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
243265012385	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
243265012386	trimerization site [polypeptide binding]; other site
243265012387	active site
243265012388	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
243265012389	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
243265012390	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265012391	catalytic residue [active]
243265012392	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
243265012393	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
243265012394	dimer interface [polypeptide binding]; other site
243265012395	active site
243265012396	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
243265012397	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
243265012398	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
243265012399	NAD(P) binding site [chemical binding]; other site
243265012400	active site
243265012401	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
243265012402	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
243265012403	Nse4; Region: Nse4; pfam08743
243265012404	HlyD family secretion protein; Region: HlyD_3; pfam13437
243265012405	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
243265012406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265012407	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265012408	threonine dehydratase; Reviewed; Region: PRK09224
243265012409	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
243265012410	tetramer interface [polypeptide binding]; other site
243265012411	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012412	catalytic residue [active]
243265012413	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
243265012414	putative Ile/Val binding site [chemical binding]; other site
243265012415	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
243265012416	putative Ile/Val binding site [chemical binding]; other site
243265012417	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
243265012418	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
243265012419	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
243265012420	homodimer interface [polypeptide binding]; other site
243265012421	substrate-cofactor binding pocket; other site
243265012422	catalytic residue [active]
243265012423	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
243265012424	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
243265012425	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
243265012426	PYR/PP interface [polypeptide binding]; other site
243265012427	dimer interface [polypeptide binding]; other site
243265012428	TPP binding site [chemical binding]; other site
243265012429	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
243265012430	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
243265012431	TPP-binding site [chemical binding]; other site
243265012432	dimer interface [polypeptide binding]; other site
243265012433	putative ATP-dependent protease; Provisional; Region: PRK09862
243265012434	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
243265012435	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
243265012436	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
243265012437	hypothetical protein; Provisional; Region: PRK11027
243265012438	transcriptional regulator HdfR; Provisional; Region: PRK03601
243265012439	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265012440	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
243265012441	dimerization interface [polypeptide binding]; other site
243265012442	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
243265012443	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
243265012444	trimer interface [polypeptide binding]; other site
243265012445	putative metal binding site [ion binding]; other site
243265012446	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
243265012447	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
243265012448	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
243265012449	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
243265012450	NAD(P) binding site [chemical binding]; other site
243265012451	shikimate binding site; other site
243265012452	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
243265012453	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
243265012454	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
243265012455	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
243265012456	hypothetical protein; Provisional; Region: PRK10736
243265012457	DNA protecting protein DprA; Region: dprA; TIGR00732
243265012458	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
243265012459	active site
243265012460	catalytic residues [active]
243265012461	metal binding site [ion binding]; metal-binding site
243265012462	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
243265012463	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
243265012464	putative active site [active]
243265012465	substrate binding site [chemical binding]; other site
243265012466	putative cosubstrate binding site; other site
243265012467	catalytic site [active]
243265012468	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
243265012469	substrate binding site [chemical binding]; other site
243265012470	16S rRNA methyltransferase B; Provisional; Region: PRK10901
243265012471	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
243265012472	putative RNA binding site [nucleotide binding]; other site
243265012473	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265012474	S-adenosylmethionine binding site [chemical binding]; other site
243265012475	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
243265012476	TrkA-N domain; Region: TrkA_N; pfam02254
243265012477	TrkA-C domain; Region: TrkA_C; pfam02080
243265012478	TrkA-N domain; Region: TrkA_N; pfam02254
243265012479	TrkA-C domain; Region: TrkA_C; pfam02080
243265012480	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
243265012481	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
243265012482	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
243265012483	DNA binding residues [nucleotide binding]
243265012484	dimer interface [polypeptide binding]; other site
243265012485	metal binding site [ion binding]; metal-binding site
243265012486	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
243265012487	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
243265012488	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
243265012489	alphaNTD homodimer interface [polypeptide binding]; other site
243265012490	alphaNTD - beta interaction site [polypeptide binding]; other site
243265012491	alphaNTD - beta' interaction site [polypeptide binding]; other site
243265012492	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
243265012493	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
243265012494	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
243265012495	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
243265012496	RNA binding surface [nucleotide binding]; other site
243265012497	30S ribosomal protein S11; Validated; Region: PRK05309
243265012498	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
243265012499	30S ribosomal protein S13; Region: bact_S13; TIGR03631
243265012500	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
243265012501	SecY translocase; Region: SecY; pfam00344
243265012502	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
243265012503	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
243265012504	23S rRNA binding site [nucleotide binding]; other site
243265012505	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
243265012506	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
243265012507	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
243265012508	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
243265012509	5S rRNA interface [nucleotide binding]; other site
243265012510	23S rRNA interface [nucleotide binding]; other site
243265012511	L5 interface [polypeptide binding]; other site
243265012512	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
243265012513	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
243265012514	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
243265012515	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
243265012516	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
243265012517	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
243265012518	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
243265012519	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
243265012520	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
243265012521	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
243265012522	RNA binding site [nucleotide binding]; other site
243265012523	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
243265012524	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
243265012525	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
243265012526	23S rRNA interface [nucleotide binding]; other site
243265012527	putative translocon interaction site; other site
243265012528	signal recognition particle (SRP54) interaction site; other site
243265012529	L23 interface [polypeptide binding]; other site
243265012530	trigger factor interaction site; other site
243265012531	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
243265012532	23S rRNA interface [nucleotide binding]; other site
243265012533	5S rRNA interface [nucleotide binding]; other site
243265012534	putative antibiotic binding site [chemical binding]; other site
243265012535	L25 interface [polypeptide binding]; other site
243265012536	L27 interface [polypeptide binding]; other site
243265012537	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
243265012538	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
243265012539	G-X-X-G motif; other site
243265012540	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
243265012541	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
243265012542	protein-rRNA interface [nucleotide binding]; other site
243265012543	putative translocon binding site; other site
243265012544	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
243265012545	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
243265012546	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
243265012547	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
243265012548	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
243265012549	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
243265012550	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
243265012551	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
243265012552	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
243265012553	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
243265012554	heme binding site [chemical binding]; other site
243265012555	ferroxidase pore; other site
243265012556	ferroxidase diiron center [ion binding]; other site
243265012557	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
243265012558	elongation factor Tu; Reviewed; Region: PRK00049
243265012559	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
243265012560	G1 box; other site
243265012561	GEF interaction site [polypeptide binding]; other site
243265012562	GTP/Mg2+ binding site [chemical binding]; other site
243265012563	Switch I region; other site
243265012564	G2 box; other site
243265012565	G3 box; other site
243265012566	Switch II region; other site
243265012567	G4 box; other site
243265012568	G5 box; other site
243265012569	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
243265012570	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
243265012571	Antibiotic Binding Site [chemical binding]; other site
243265012572	pantothenate kinase; Provisional; Region: PRK05439
243265012573	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
243265012574	ATP-binding site [chemical binding]; other site
243265012575	CoA-binding site [chemical binding]; other site
243265012576	Mg2+-binding site [ion binding]; other site
243265012577	Biotin operon repressor [Transcription]; Region: BirA; COG1654
243265012578	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
243265012579	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
243265012580	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
243265012581	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
243265012582	FAD binding domain; Region: FAD_binding_4; pfam01565
243265012583	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
243265012584	glutamate racemase; Provisional; Region: PRK00865
243265012585	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
243265012586	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
243265012587	N-terminal plug; other site
243265012588	ligand-binding site [chemical binding]; other site
243265012589	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
243265012590	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265012591	S-adenosylmethionine binding site [chemical binding]; other site
243265012592	hypothetical protein; Provisional; Region: PRK11056
243265012593	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
243265012594	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
243265012595	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
243265012596	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
243265012597	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
243265012598	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
243265012599	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
243265012600	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
243265012601	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
243265012602	dimerization interface [polypeptide binding]; other site
243265012603	argininosuccinate lyase; Provisional; Region: PRK04833
243265012604	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
243265012605	active sites [active]
243265012606	tetramer interface [polypeptide binding]; other site
243265012607	argininosuccinate synthase; Provisional; Region: PRK13820
243265012608	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
243265012609	ANP binding site [chemical binding]; other site
243265012610	Substrate Binding Site II [chemical binding]; other site
243265012611	Substrate Binding Site I [chemical binding]; other site
243265012612	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
243265012613	nucleotide binding site [chemical binding]; other site
243265012614	N-acetyl-L-glutamate binding site [chemical binding]; other site
243265012615	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
243265012616	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
243265012617	acetylornithine deacetylase; Provisional; Region: PRK05111
243265012618	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
243265012619	metal binding site [ion binding]; metal-binding site
243265012620	putative dimer interface [polypeptide binding]; other site
243265012621	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
243265012622	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
243265012623	Tir chaperone protein (CesT) family; Region: CesT; cl08444
243265012624	Homeodomain-like domain; Region: HTH_23; pfam13384
243265012625	Winged helix-turn helix; Region: HTH_29; pfam13551
243265012626	Winged helix-turn helix; Region: HTH_33; pfam13592
243265012627	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265012628	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265012629	Truncated gene. Similar to the C-terminal region of transposase, IS630 family (ISPlu3-p)
243265012630	Truncated gene. Similar to the N-terminal region of transposase, IS630 family (ISPlu3-p)
243265012631	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
243265012632	FAD binding site [chemical binding]; other site
243265012633	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
243265012634	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
243265012635	putative catalytic residues [active]
243265012636	putative nucleotide binding site [chemical binding]; other site
243265012637	putative aspartate binding site [chemical binding]; other site
243265012638	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
243265012639	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
243265012640	cystathionine gamma-synthase; Provisional; Region: PRK08045
243265012641	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
243265012642	homodimer interface [polypeptide binding]; other site
243265012643	substrate-cofactor binding pocket; other site
243265012644	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012645	catalytic residue [active]
243265012646	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
243265012647	dimerization interface [polypeptide binding]; other site
243265012648	DNA binding site [nucleotide binding]
243265012649	corepressor binding sites; other site
243265012650	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
243265012651	primosome assembly protein PriA; Validated; Region: PRK05580
243265012652	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
243265012653	ATP binding site [chemical binding]; other site
243265012654	putative Mg++ binding site [ion binding]; other site
243265012655	helicase superfamily c-terminal domain; Region: HELICc; smart00490
243265012656	ATP-binding site [chemical binding]; other site
243265012657	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
243265012658	DNA binding site [nucleotide binding]
243265012659	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
243265012660	domain linker motif; other site
243265012661	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
243265012662	dimerization interface [polypeptide binding]; other site
243265012663	ligand binding site [chemical binding]; other site
243265012664	Sporulation related domain; Region: SPOR; cl10051
243265012665	cell division protein FtsN; Provisional; Region: PRK12757
243265012666	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
243265012667	active site
243265012668	HslU subunit interaction site [polypeptide binding]; other site
243265012669	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
243265012670	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265012671	Walker A motif; other site
243265012672	ATP binding site [chemical binding]; other site
243265012673	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
243265012674	Walker B motif; other site
243265012675	arginine finger; other site
243265012676	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
243265012677	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
243265012678	UbiA prenyltransferase family; Region: UbiA; pfam01040
243265012679	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
243265012680	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3074
243265012681	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
243265012682	amphipathic channel; other site
243265012683	Asn-Pro-Ala signature motifs; other site
243265012684	glycerol kinase; Provisional; Region: glpK; PRK00047
243265012685	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
243265012686	N- and C-terminal domain interface [polypeptide binding]; other site
243265012687	active site
243265012688	MgATP binding site [chemical binding]; other site
243265012689	catalytic site [active]
243265012690	metal binding site [ion binding]; metal-binding site
243265012691	glycerol binding site [chemical binding]; other site
243265012692	homotetramer interface [polypeptide binding]; other site
243265012693	homodimer interface [polypeptide binding]; other site
243265012694	FBP binding site [chemical binding]; other site
243265012695	protein IIAGlc interface [polypeptide binding]; other site
243265012696	ferredoxin-NADP reductase; Provisional; Region: PRK10926
243265012697	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
243265012698	FAD binding pocket [chemical binding]; other site
243265012699	FAD binding motif [chemical binding]; other site
243265012700	phosphate binding motif [ion binding]; other site
243265012701	beta-alpha-beta structure motif; other site
243265012702	NAD binding pocket [chemical binding]; other site
243265012703	Predicted membrane protein [Function unknown]; Region: COG3152
243265012704	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
243265012705	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
243265012706	triosephosphate isomerase; Provisional; Region: PRK14567
243265012707	substrate binding site [chemical binding]; other site
243265012708	dimer interface [polypeptide binding]; other site
243265012709	catalytic triad [active]
243265012710	sulfate transporter subunit; Provisional; Region: PRK10752
243265012711	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
243265012712	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
243265012713	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
243265012714	active site
243265012715	ADP/pyrophosphate binding site [chemical binding]; other site
243265012716	dimerization interface [polypeptide binding]; other site
243265012717	allosteric effector site; other site
243265012718	fructose-1,6-bisphosphate binding site; other site
243265012719	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
243265012720	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
243265012721	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
243265012722	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
243265012723	putative acyl-acceptor binding pocket; other site
243265012724	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
243265012725	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
243265012726	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265012727	non-specific DNA binding site [nucleotide binding]; other site
243265012728	salt bridge; other site
243265012729	sequence-specific DNA binding site [nucleotide binding]; other site
243265012730	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
243265012731	Phage-related protein [Function unknown]; Region: COG4679
243265012732	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
243265012733	Uncharacterized protein family (UPF0156); Region: RHH_2; pfam03693
243265012734	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
243265012735	Truncated gene. Highly similar to the N-terminal region of the proteic killer suppression protein HigA
243265012736	Truncated gene. Similar to the C-terminal region of proteic killer suppression protein HigA.
243265012737	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265012738	non-specific DNA binding site [nucleotide binding]; other site
243265012739	salt bridge; other site
243265012740	sequence-specific DNA binding site [nucleotide binding]; other site
243265012741	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
243265012742	active site
243265012743	DNA binding site [nucleotide binding]
243265012744	Int/Topo IB signature motif; other site
243265012745	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
243265012746	HicB family; Region: HicB; pfam05534
243265012747	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
243265012748	DNA binding site [nucleotide binding]
243265012749	Int/Topo IB signature motif; other site
243265012750	active site
243265012751	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
243265012752	dimer interface [polypeptide binding]; other site
243265012753	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
243265012754	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
243265012755	active site
243265012756	phosphorylation site [posttranslational modification]
243265012757	intermolecular recognition site; other site
243265012758	dimerization interface [polypeptide binding]; other site
243265012759	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
243265012760	DNA binding site [nucleotide binding]
243265012761	two-component sensor protein; Provisional; Region: cpxA; PRK09470
243265012762	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
243265012763	dimerization interface [polypeptide binding]; other site
243265012764	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
243265012765	dimer interface [polypeptide binding]; other site
243265012766	phosphorylation site [posttranslational modification]
243265012767	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
243265012768	ATP binding site [chemical binding]; other site
243265012769	Mg2+ binding site [ion binding]; other site
243265012770	G-X-G motif; other site
243265012771	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
243265012772	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
243265012773	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
243265012774	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
243265012775	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
243265012776	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
243265012777	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
243265012778	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
243265012779	putative trimer interface [polypeptide binding]; other site
243265012780	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
243265012781	putative CoA binding site [chemical binding]; other site
243265012782	putative trimer interface [polypeptide binding]; other site
243265012783	putative active site [active]
243265012784	putative substrate binding site [chemical binding]; other site
243265012785	putative CoA binding site [chemical binding]; other site
243265012786	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
243265012787	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
243265012788	inhibitor-cofactor binding pocket; inhibition site
243265012789	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012790	catalytic residue [active]
243265012791	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
243265012792	D-glucuronyl C5-epimerase C-terminus; Region: C5-epim_C; pfam06662
243265012793	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265012794	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
243265012795	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
243265012796	active site
243265012797	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
243265012798	homodimer interface [polypeptide binding]; other site
243265012799	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
243265012800	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
243265012801	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265012802	ExoA is involved in the biosynthesis of succinoglycan; Region: Succinoglycan_BP_ExoA; cd02525
243265012803	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
243265012804	Ligand binding site; other site
243265012805	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
243265012806	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
243265012807	inhibitor-cofactor binding pocket; inhibition site
243265012808	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012809	catalytic residue [active]
243265012810	Bacterial sugar transferase; Region: Bac_transf; pfam02397
243265012811	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
243265012812	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
243265012813	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
243265012814	NAD(P) binding site [chemical binding]; other site
243265012815	homodimer interface [polypeptide binding]; other site
243265012816	substrate binding site [chemical binding]; other site
243265012817	active site
243265012818	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
243265012819	EamA-like transporter family; Region: EamA; cl17759
243265012820	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
243265012821	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
243265012822	substrate binding site; other site
243265012823	tetramer interface; other site
243265012824	WxcM-like, C-terminal; Region: FdtA; pfam05523
243265012825	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
243265012826	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
243265012827	inhibitor-cofactor binding pocket; inhibition site
243265012828	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012829	catalytic residue [active]
243265012830	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
243265012831	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
243265012832	Homeodomain-like domain; Region: HTH_23; pfam13384
243265012833	Winged helix-turn helix; Region: HTH_29; pfam13551
243265012834	Winged helix-turn helix; Region: HTH_33; pfam13592
243265012835	DDE superfamily endonuclease; Region: DDE_3; pfam13358
243265012836	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
243265012837	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
243265012838	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
243265012839	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
243265012840	active site
243265012841	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
243265012842	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265012843	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
243265012844	Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only]; Region: COG2605
243265012845	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
243265012846	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
243265012847	dimer interface [polypeptide binding]; other site
243265012848	active site
243265012849	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
243265012850	WcbM_like is a subfamily of nucleotidyl transferases; Region: NTP_transferase_WcbM_like; cd06915
243265012851	Substrate binding site; other site
243265012852	Mg++ binding site; other site
243265012853	metal-binding site
243265012854	Mg++ binding site; other site
243265012855	metal-binding site
243265012856	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
243265012857	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
243265012858	active site
243265012859	motif I; other site
243265012860	motif II; other site
243265012861	Similar to the N-terminal region of transposase, IS110 family
243265012862	Similar to the central region of transposase, IS110 family
243265012863	Similar to C-terminal region of transposase, IS110 family
243265012864	Truncated gene. Similar to the N-terminal region of transposase, IS30 family
243265012865	Formyltransferase, catalytic core domain; Region: FMT_core; cd08369
243265012866	active site
243265012867	substrate binding site [chemical binding]; other site
243265012868	cosubstrate binding site; other site
243265012869	catalytic site [active]
243265012870	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
243265012871	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
243265012872	UDP-glucose 4-epimerase; Region: PLN02240
243265012873	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
243265012874	NAD binding site [chemical binding]; other site
243265012875	homodimer interface [polypeptide binding]; other site
243265012876	active site
243265012877	substrate binding site [chemical binding]; other site
243265012878	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
243265012879	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
243265012880	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265012881	S-adenosylmethionine binding site [chemical binding]; other site
243265012882	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
243265012883	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
243265012884	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265012885	S-adenosylmethionine binding site [chemical binding]; other site
243265012886	serine acetyltransferase; Provisional; Region: cysE; PRK11132
243265012887	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
243265012888	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
243265012889	trimer interface [polypeptide binding]; other site
243265012890	active site
243265012891	substrate binding site [chemical binding]; other site
243265012892	CoA binding site [chemical binding]; other site
243265012893	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
243265012894	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
243265012895	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
243265012896	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
243265012897	SecA binding site; other site
243265012898	Preprotein binding site; other site
243265012899	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
243265012900	active site residue [active]
243265012901	AmiB activator; Provisional; Region: PRK11637
243265012902	Peptidase family M23; Region: Peptidase_M23; pfam01551
243265012903	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
243265012904	NodB motif; other site
243265012905	putative active site [active]
243265012906	putative catalytic site [active]
243265012907	Zn binding site [ion binding]; other site
243265012908	Transposase IS200 like; Region: Y1_Tnp; pfam01797
243265012909	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
243265012910	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
243265012911	dimer interface [polypeptide binding]; other site
243265012912	active site
243265012913	CoA binding pocket [chemical binding]; other site
243265012914	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
243265012915	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
243265012916	NAD(P) binding site [chemical binding]; other site
243265012917	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
243265012918	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
243265012919	substrate-cofactor binding pocket; other site
243265012920	pyridoxal 5'-phosphate binding site [chemical binding]; other site
243265012921	catalytic residue [active]
243265012922	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
243265012923	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
243265012924	NADP binding site [chemical binding]; other site
243265012925	homopentamer interface [polypeptide binding]; other site
243265012926	substrate binding site [chemical binding]; other site
243265012927	active site
243265012928	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
243265012929	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
243265012930	putative active site [active]
243265012931	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
243265012932	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
243265012933	putative active site [active]
243265012934	Putative catalytic domain of lipopolysaccharide biosynthesis protein WalW and its bacterial homologs; Region: CE4_WalW; cd10935
243265012935	putative active site [active]
243265012936	putative catalytic site [active]
243265012937	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265012938	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
243265012939	putative ADP-binding pocket [chemical binding]; other site
243265012940	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265012941	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
243265012942	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
243265012943	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
243265012944	putative active site [active]
243265012945	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
243265012946	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
243265012947	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
243265012948	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
243265012949	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
243265012950	putative metal binding site; other site
243265012951	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
243265012952	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
243265012953	active site
243265012954	(T/H)XGH motif; other site
243265012955	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
243265012956	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
243265012957	DNA binding site [nucleotide binding]
243265012958	catalytic residue [active]
243265012959	H2TH interface [polypeptide binding]; other site
243265012960	putative catalytic residues [active]
243265012961	turnover-facilitating residue; other site
243265012962	intercalation triad [nucleotide binding]; other site
243265012963	8OG recognition residue [nucleotide binding]; other site
243265012964	putative reading head residues; other site
243265012965	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
243265012966	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
243265012967	O-antigen ligase RfaL; Provisional; Region: PRK15487
243265012968	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
243265012969	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265012970	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
243265012971	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265012972	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
243265012973	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
243265012974	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
243265012975	putative active site [active]
243265012976	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
243265012977	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
243265012978	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
243265012979	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
243265012980	hypothetical protein; Reviewed; Region: PRK00024
243265012981	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
243265012982	MPN+ (JAMM) motif; other site
243265012983	Zinc-binding site [ion binding]; other site
243265012984	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
243265012985	Flavoprotein; Region: Flavoprotein; pfam02441
243265012986	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
243265012987	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
243265012988	trimer interface [polypeptide binding]; other site
243265012989	active site
243265012990	division inhibitor protein; Provisional; Region: slmA; PRK09480
243265012991	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
243265012992	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
243265012993	active site
243265012994	ribonuclease PH; Reviewed; Region: rph; PRK00173
243265012995	Ribonuclease PH; Region: RNase_PH_bact; cd11362
243265012996	hexamer interface [polypeptide binding]; other site
243265012997	active site
243265012998	hypothetical protein; Provisional; Region: PRK11820
243265012999	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
243265013000	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
243265013001	Probable truncated gene
243265013002	HicB family; Region: HicB; pfam05534
243265013003	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
243265013004	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
243265013005	putative active site [active]
243265013006	putative NTP binding site [chemical binding]; other site
243265013007	putative nucleic acid binding site [nucleotide binding]; other site
243265013008	Fic family protein [Function unknown]; Region: COG3177
243265013009	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
243265013010	Fic/DOC family; Region: Fic; pfam02661
243265013011	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
243265013012	H+ Antiporter protein; Region: 2A0121; TIGR00900
243265013013	putative substrate translocation pore; other site
243265013014	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
243265013015	YegV-like sugar kinase.  Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YegV_kinase_like; cd01944
243265013016	substrate binding site [chemical binding]; other site
243265013017	ATP binding site [chemical binding]; other site
243265013018	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
243265013019	Truncated gene, N-terminal region of FdoG
243265013020	Truncated gene, N-terminal region of FdoG
243265013021	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
243265013022	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
243265013023	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
243265013024	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
243265013025	O-methyltransferase; Region: Methyltransf_2; pfam00891
243265013026	Methyltransferase domain; Region: Methyltransf_23; pfam13489
243265013027	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265013028	S-adenosylmethionine binding site [chemical binding]; other site
243265013029	Methyltransferase domain; Region: Methyltransf_23; pfam13489
243265013030	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265013031	S-adenosylmethionine binding site [chemical binding]; other site
243265013032	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
243265013033	Helix-turn-helix domain; Region: HTH_38; pfam13936
243265013034	Homeodomain-like domain; Region: HTH_32; pfam13565
243265013035	Integrase core domain; Region: rve; pfam00665
243265013036	Methyltransferase domain; Region: Methyltransf_23; pfam13489
243265013037	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
243265013038	S-adenosylmethionine binding site [chemical binding]; other site
243265013039	O-methyltransferase; Region: Methyltransf_2; pfam00891
243265013040	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
243265013041	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
243265013042	selenocysteine synthase; Provisional; Region: PRK04311
243265013043	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
243265013044	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
243265013045	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
243265013046	catalytic residue [active]
243265013047	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
243265013048	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
243265013049	G1 box; other site
243265013050	putative GEF interaction site [polypeptide binding]; other site
243265013051	GTP/Mg2+ binding site [chemical binding]; other site
243265013052	Switch I region; other site
243265013053	G2 box; other site
243265013054	G3 box; other site
243265013055	Switch II region; other site
243265013056	G4 box; other site
243265013057	G5 box; other site
243265013058	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
243265013059	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
243265013060	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
243265013061	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
243265013062	Sulfatase; Region: Sulfatase; cl17466
243265013063	HipA N-terminal domain; Region: Couple_hipA; pfam13657
243265013064	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
243265013065	HipA-like N-terminal domain; Region: HipA_N; pfam07805
243265013066	HipA-like C-terminal domain; Region: HipA_C; pfam07804
243265013067	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
243265013068	non-specific DNA binding site [nucleotide binding]; other site
243265013069	salt bridge; other site
243265013070	sequence-specific DNA binding site [nucleotide binding]; other site
243265013071	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
243265013072	AAA domain; Region: AAA_23; pfam13476
243265013073	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
243265013074	Walker A/P-loop; other site
243265013075	ATP binding site [chemical binding]; other site
243265013076	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
243265013077	Divergent AAA domain; Region: AAA_4; pfam04326
243265013078	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
243265013079	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
243265013080	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
243265013081	trmE is a tRNA modification GTPase; Region: trmE; cd04164
243265013082	G1 box; other site
243265013083	GTP/Mg2+ binding site [chemical binding]; other site
243265013084	Switch I region; other site
243265013085	G2 box; other site
243265013086	Switch II region; other site
243265013087	G3 box; other site
243265013088	G4 box; other site
243265013089	G5 box; other site
243265013090	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
243265013091	membrane protein insertase; Provisional; Region: PRK01318
243265013092	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
243265013093	hypothetical protein; Validated; Region: PRK00041
243265013094	ribonuclease P; Reviewed; Region: rnpA; PRK01732
243265013095	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399