-- dump date 20140619_235106 -- class Genbank::CDS -- table cds_note -- id note YP_001796946.1 KEGG: pnu:Pnuc_0001 chromosomal replication initiator protein DnaA; TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator DnaA domain; Chromosomal replication initiator DnaA; SMART: AAA ATPase YP_001796947.1 binds the polymerase to DNA and acts as a sliding clamp YP_001796948.1 KEGG: pnu:Pnuc_0003 DNA gyrase, B subunit; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase subunit B domain protein; ATP-binding region ATPase domain protein; TOPRIM domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II YP_001796949.1 PFAM: nuclear protein SET; KEGG: pnu:Pnuc_0004 nuclear protein SET YP_001796950.1 KEGG: pnu:Pnuc_0005 hypothetical protein YP_001796951.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_0006 ABC transporter YP_001796952.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_0007 ABC transporter YP_001796953.1 PFAM: Extracellular ligand-binding receptor; KEGG: azo:azo0119 probable ABC transporter substrate binding protein YP_001796954.1 PFAM: inner-membrane translocator; KEGG: eba:ebA3426 probable transmembrane ABC transporter protein YP_001796955.1 PFAM: inner-membrane translocator; KEGG: eba:ebA3425 possible ABC transporter, permease protein precursor YP_001796956.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001796957.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein; KEGG: pnu:Pnuc_0016 methyltransferase GidB YP_001796958.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: pnu:Pnuc_0017 cobyrinic acid a,c-diamide synthase YP_001796959.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: pnu:Pnuc_0018 ParB-like partition protein YP_001796960.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001796961.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001796962.1 TIGRFAM: ATP synthase F0, B subunit; PFAM: H+transporting two-sector ATPase B/B' subunit; KEGG: pnu:Pnuc_0022 ATP synthase F0, B subunit YP_001796963.1 TIGRFAM: ATP synthase F1, delta subunit; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; KEGG: pnu:Pnuc_0023 ATP synthase F1, delta subunit YP_001796964.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001796965.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001796966.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001796967.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001796968.1 KEGG: pnu:Pnuc_0028 uroporphyrinogen decarboxylase; TIGRFAM: uroporphyrinogen decarboxylase; PFAM: Uroporphyrinogen decarboxylase (URO-D) YP_001796969.1 KEGG: pnu:Pnuc_0029 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001796970.1 PFAM: glycine cleavage H-protein; KEGG: pnu:Pnuc_0030 glycine cleavage system H protein YP_001796971.1 PFAM: fatty acid desaturase; KEGG: pnu:Pnuc_0032 fatty acid desaturase YP_001796972.1 PFAM: cytochrome c class I; KEGG: pnu:Pnuc_0033 cytochrome c, class I YP_001796973.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pnu:Pnuc_0034 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001796974.1 TIGRFAM: phosphoheptose isomerase; PFAM: sugar isomerase (SIS); KEGG: pnu:Pnuc_0035 phosphoheptose isomerase YP_001796975.1 PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: pnu:Pnuc_0036 transport-associated YP_001796976.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pnu:Pnuc_0038 GCN5-related N-acetyltransferase YP_001796977.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001796978.1 TIGRFAM: preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; KEGG: pnu:Pnuc_0040 preprotein translocase, SecE subunit YP_001796979.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: KOW domain protein; NGN domain protein; KEGG: pnu:Pnuc_0041 NusG antitermination factor YP_001796980.1 binds directly to 23S ribosomal RNA YP_001796981.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001796982.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001796983.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001796984.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001796985.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001796987.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001796988.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001796989.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001796990.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001796991.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001796992.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001796993.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001796994.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001796995.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001796996.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001796997.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001796998.1 KEGG: pnu:Pnuc_0059 ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; KH type 2 domain protein; Ribosomal protein S3 domain; SMART: KH domain protein YP_001796999.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001797000.1 one of the stabilizing components for the large ribosomal subunit YP_001797001.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001797002.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001797003.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001797004.1 PFAM: ribosomal protein L5; KEGG: pnu:Pnuc_0065 ribosomal protein L5 YP_001797005.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001797006.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001797007.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001797008.1 binds 5S rRNA along with protein L5 and L25 YP_001797009.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001797010.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001797011.1 late assembly protein YP_001797012.1 TIGRFAM: preprotein translocase, SecY subunit; PFAM: SecY protein; KEGG: pnu:Pnuc_0073 preprotein translocase, SecY subunit YP_001797013.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001797014.1 PFAM: ribosomal protein L36; KEGG: rso:RSc2997 50S ribosomal protein L36 YP_001797015.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001797016.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001797017.1 PFAM: ribosomal protein S4; RNA-binding S4 domain protein; KEGG: pnu:Pnuc_0077 ribosomal protein S4 YP_001797018.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001797019.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001797020.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: pnu:Pnuc_0080 CutA1 divalent ion tolerance protein YP_001797021.1 PFAM: cytochrome c biogenesis protein transmembrane region; Thioredoxin domain; KEGG: pnu:Pnuc_0081 protein-disulfide reductase YP_001797022.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001797023.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001797024.1 PFAM: cytochrome c class I; KEGG: pnu:Pnuc_0085 cytochrome c553-like protein YP_001797025.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: pnu:Pnuc_0086 diaminopimelate decarboxylase YP_001797026.1 TIGRFAM: iron donor protein CyaY; PFAM: Frataxin family protein; KEGG: pnu:Pnuc_0087 frataxin family protein YP_001797027.1 PFAM: 3-dehydroquinate synthase; KEGG: pnu:Pnuc_0088 3-dehydroquinate synthase YP_001797028.1 PFAM: shikimate kinase; KEGG: pnu:Pnuc_0089 shikimate kinase YP_001797029.1 PFAM: type II and III secretion system protein; KEGG: pnu:Pnuc_0090 type II and III secretion system protein YP_001797030.1 KEGG: pnu:Pnuc_0092 penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase YP_001797031.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_0096 ABC transporter YP_001797032.1 PFAM: protein of unknown function DUF140; KEGG: pnu:Pnuc_0097 protein of unknown function DUF140 YP_001797033.1 PFAM: Mammalian cell entry related domain protein; KEGG: pnu:Pnuc_0098 mammalian cell entry related domain protein YP_001797034.1 PFAM: VacJ family lipoprotein; KEGG: pnu:Pnuc_0099 VacJ family lipoprotein YP_001797035.1 PFAM: toluene tolerance family protein; KEGG: pnu:Pnuc_0100 toluene tolerance family protein YP_001797036.1 KEGG: pnu:Pnuc_0101 sulfate transporter/antisigma-factor antagonist STAS YP_001797037.1 PFAM: BolA family protein; KEGG: pnu:Pnuc_0104 BolA family protein YP_001797038.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001797039.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001797040.1 PFAM: histidinol dehydrogenase; KEGG: pnu:Pnuc_0107 histidinol dehydrogenase YP_001797041.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001797042.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001797043.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001797044.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001797045.1 PFAM: phosphoribosyl-AMP cyclohydrolase; KEGG: pnu:Pnuc_0113 phosphoribosyl-AMP cyclohydrolase YP_001797046.1 TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: pnu:Pnuc_0114 phosphoribosyl-ATP pyrophosphohydrolase YP_001797047.1 PFAM: histidine triad (HIT) protein; KEGG: pnu:Pnuc_0115 histidine triad (HIT) protein YP_001797048.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001797049.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: pnu:Pnuc_0117 sec-independent translocase YP_001797050.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: pnu:Pnuc_0118 sec-independent protein translocase, TatC subunit YP_001797051.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: zmo:ZMO1969 hypothetical protein YP_001797052.1 PFAM: porin Gram-negative type; KEGG: pnu:Pnuc_0120 porin, gram-negative type YP_001797053.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pnu:Pnuc_0121 TPR repeat-containing protein YP_001797055.1 KEGG: pnu:Pnuc_0989 polar amino acid ABC transporter, inner membrane subunit YP_001797056.1 KEGG: pnu:Pnuc_0988 polar amino acid ABC transporter, inner membrane subunit YP_001797057.1 KEGG: pnu:Pnuc_0988 polar amino acid ABC transporter, inner membrane subunit YP_001797058.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: pnu:Pnuc_0123 peptidase S1 and S6, chymotrypsin/Hap YP_001797059.1 TIGRFAM: large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel; KEGG: pnu:Pnuc_0124 large conductance mechanosensitive channel protein YP_001797060.1 KEGG: pnu:Pnuc_0125 ubiquinol-cytochrome c reductase, iron-sulfur subunit; TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001797061.1 PFAM: Cytochrome b/b6 domain; KEGG: pnu:Pnuc_0126 cytochrome b/b6, N-terminal domain YP_001797062.1 PFAM: cytochrome c1; KEGG: pnu:Pnuc_0127 cytochrome c1 YP_001797063.1 PFAM: glutathione S-transferase domain; KEGG: pnu:Pnuc_0128 glutathione S-transferase, N-terminal domain YP_001797064.1 PFAM: Stringent starvation protein B; KEGG: pnu:Pnuc_0129 stringent starvation protein B YP_001797066.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: bxe:Bxe_A3016 putative TPR/sulfotransferase domain protein, FlbA-like YP_001797067.1 KEGG: pnu:Pnuc_0250 hypothetical protein YP_001797068.1 PFAM: protein of unknown function DUF195; KEGG: pnu:Pnuc_0133 protein of unknown function DUF195 YP_001797069.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: pnu:Pnuc_0134 glutaredoxin-like protein YP_001797070.1 TIGRFAM: modification methylase, HemK family; protein-(glutamine-N5) methyltransferase, release factor-specific; PFAM: methyltransferase small; KEGG: pnu:Pnuc_0135 modification methylase, HemK family YP_001797071.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001797072.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001797073.1 KEGG: azc:AZC_0588 hypothetical protein YP_001797074.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: pnu:Pnuc_0138 uracil-DNA glycosylase superfamily YP_001797075.1 PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: pnu:Pnuc_0139 peptidase M61 domain protein YP_001797076.1 KEGG: pnu:Pnuc_0140 putative thiol:disulfide interchange protein YP_001797077.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: pnu:Pnuc_0141 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001797078.1 TIGRFAM: GTP-binding protein YchF; PFAM: GTP-binding protein HSR1-related; Protein of unknown function DUF933; KEGG: pnu:Pnuc_0142 GTP-binding protein YchF YP_001797079.1 KEGG: pnu:Pnuc_0143 hypothetical protein YP_001797080.1 KEGG: pnu:Pnuc_0143 hypothetical protein YP_001797081.1 KEGG: pnu:Pnuc_0144 hypothetical protein YP_001797082.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001797083.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001797084.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pnu:Pnuc_0147 glutamine amidotransferase of anthranilate synthase YP_001797085.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001797086.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: pnu:Pnuc_0149 ribulose-phosphate 3-epimerase YP_001797087.1 protein associated with Co2+ and Mg2+ efflux YP_001797088.1 PFAM: MltA domain protein; 3D domain protein; KEGG: pnu:Pnuc_0151 MltA domain protein YP_001797089.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: reh:H16_A3307 putative enoyl-CoA hydratase YP_001797090.1 PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: pnu:Pnuc_0154 8-amino-7-oxononanoate synthase YP_001797091.1 KEGG: pnu:Pnuc_0157 putative ubiquinone biosynthesis protein YP_001797092.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: pnu:Pnuc_0159 S-adenosyl-methyltransferase MraW YP_001797093.1 PFAM: cell division protein FtsL; KEGG: pnu:Pnuc_0160 cell division protein FtsL YP_001797094.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: pnu:Pnuc_0161 peptidoglycan glycosyltransferase YP_001797095.1 TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pnu:Pnuc_0162 UDP-N-acetylmuramyl-tripeptide synthetase YP_001797096.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pnu:Pnuc_0163 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase YP_001797097.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001797098.1 TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pnu:Pnuc_0165 UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_001797099.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: pnu:Pnuc_0166 cell division protein FtsW YP_001797100.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001797101.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001797102.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001797103.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein FtsQ-type; KEGG: pnu:Pnuc_0170 polypeptide-transport-associated domain protein, FtsQ-type YP_001797104.1 PFAM: cell division protein FtsA; KEGG: pnu:Pnuc_0171 cell division protein FtsA YP_001797105.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001797106.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pnu:Pnuc_0173 redoxin domain protein YP_001797107.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001797108.1 KEGG: pnu:Pnuc_0175 hypothetical protein YP_001797109.1 TIGRFAM: preprotein translocase, SecA subunit; PFAM: SEC-C motif domain protein; SecA DEAD domain protein; SecA Wing and Scaffold; SecA preprotein cross-linking region; KEGG: pnu:Pnuc_0176 preprotein translocase, SecA subunit YP_001797110.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pna:Pnap_0050 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001797111.1 KEGG: rfr:Rfer_2847 hypothetical protein YP_001797112.1 KEGG: pnu:Pnuc_0179 arginine biosynthesis bifunctional protein ArgJ; TIGRFAM: arginine biosynthesis bifunctional protein ArgJ; PFAM: arginine biosynthesis protein ArgJ YP_001797113.1 PFAM: NUDIX hydrolase; KEGG: pnu:Pnuc_0181 NUDIX hydrolase YP_001797114.1 PFAM: protein of unknown function DUF1342; KEGG: pnu:Pnuc_0182 protein of unknown function DUF1342 YP_001797115.1 KEGG: pnu:Pnuc_0183 dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase YP_001797116.1 PFAM: peptidase A24A prepilin type IV; KEGG: pnu:Pnuc_0184 peptidase A24A, prepilin type IV YP_001797117.1 PFAM: type II secretion system protein; KEGG: pnu:Pnuc_0185 type II secretion system protein YP_001797118.1 PFAM: type II secretion system protein E; KEGG: pnu:Pnuc_0186 type II secretion system protein E YP_001797119.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: pnu:Pnuc_0187 protein of unknown function DUF21 YP_001797120.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: pnu:Pnuc_0188 methylated-DNA--protein-cysteine methyltransferase YP_001797121.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pnu:Pnuc_0192 fumarylacetoacetate (FAA) hydrolase YP_001797122.1 KEGG: bja:bll2566 hypothetical protein YP_001797123.1 PFAM: Polyprenyl synthetase; KEGG: pnu:Pnuc_0193 farnesyltranstransferase YP_001797124.1 PFAM: ribosomal protein L21; KEGG: pnu:Pnuc_0194 ribosomal protein L21 YP_001797125.1 involved in the peptidyltransferase reaction during translation YP_001797126.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001797127.1 KEGG: pnu:Pnuc_0197 glutamate 5-kinase; TIGRFAM: glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase YP_001797128.1 hydrolyzes diadenosine polyphosphate YP_001797129.1 TIGRFAM: prolyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; YbaK/prolyl-tRNA synthetase associated region; KEGG: pnu:Pnuc_0200 prolyl-tRNA synthetase YP_001797130.1 KEGG: pnu:Pnuc_0201 signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_001797131.1 PFAM: cytochrome c assembly protein; KEGG: pnu:Pnuc_0202 cytochrome c assembly protein YP_001797132.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: pnu:Pnuc_0203 N-acetyl-anhydromuranmyl-L-alanine amidase YP_001797133.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001797134.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001797135.1 KEGG: pnu:Pnuc_0206 hypothetical protein YP_001797136.1 PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0207 PfkB domain protein YP_001797137.1 KEGG: pnu:Pnuc_0208 ribosomal protein L11 methyltransferase YP_001797138.1 KEGG: pnu:Pnuc_0208 ribosomal protein L11 methyltransferase YP_001797139.1 TIGRFAM: ribosomal protein L11 methyltransferase; PFAM: ribosomal L11 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: pnu:Pnuc_0208 ribosomal protein L11 methyltransferase YP_001797140.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: pnu:Pnuc_0209 acetyl-CoA carboxylase, biotin carboxylase YP_001797141.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: pnu:Pnuc_0210 acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_001797142.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001797144.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pnu:Pnuc_0212 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001797145.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pnu:Pnuc_0213 UDP-N-acetylmuramate YP_001797146.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pnu:Pnuc_0214 short-chain dehydrogenase/reductase SDR YP_001797147.1 PFAM: ribonuclease II; KEGG: pnu:Pnuc_0215 ribonuclease II YP_001797148.1 KEGG: pnu:Pnuc_0216 TonB family protein YP_001797149.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: pnu:Pnuc_0217 shikimate 5-dehydrogenase YP_001797150.1 TIGRFAM: monofunctional biosynthetic peptidoglycan transglycosylase; PFAM: glycosyl transferase family 51; KEGG: pnu:Pnuc_0218 monofunctional biosynthetic peptidoglycan transglycosylase YP_001797151.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001797152.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: pnu:Pnuc_0220 magnesium and cobalt transport protein CorA YP_001797153.1 PFAM: CinA domain protein; KEGG: pnu:Pnuc_0221 CinA domain protein YP_001797154.1 KEGG: pnu:Pnuc_0221 CinA domain protein YP_001797155.1 PFAM: phosphatidylglycerophosphatase A; KEGG: pnu:Pnuc_0222 phosphatidylglycerophosphatase A YP_001797156.1 KEGG: pnu:Pnuc_0225 hypothetical protein YP_001797157.1 PFAM: protein of unknown function DUF558; KEGG: pnu:Pnuc_0226 protein of unknown function DUF558 YP_001797158.1 TIGRFAM: transketolase; PFAM: transketolase domain protein; transketolase central region; KEGG: pnu:Pnuc_0227 transketolase YP_001797159.1 KEGG: pnu:Pnuc_0228 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001797160.1 PFAM: ferric-uptake regulator; KEGG: pnu:Pnuc_0229 ferric uptake regulator, Fur family YP_001797161.1 PFAM: SmpA/OmlA domain protein; KEGG: pnu:Pnuc_0230 SmpA/OmlA domain protein YP_001797162.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001797163.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001797164.1 KEGG: pnu:Pnuc_0233 rare lipoprotein B precursor YP_001797165.1 TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: pnu:Pnuc_0234 DNA polymerase III, delta subunit YP_001797166.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001797167.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_0236 conserved hypothetical protein 701 YP_001797168.1 PFAM: putative RNA methylase; THUMP domain protein; KEGG: pnu:Pnuc_0237 putative RNA methylase YP_001797169.1 PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: pnu:Pnuc_0238 rubredoxin-type Fe(Cys)4 protein YP_001797170.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001797171.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001797172.1 PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: pnu:Pnuc_0241 deoxyribodipyrimidine photo-lyase YP_001797173.1 PFAM: protein of unknown function DUF179; KEGG: pnu:Pnuc_0243 protein of unknown function DUF179 YP_001797174.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001797175.1 PFAM: phosphoribosyltransferase; KEGG: pnu:Pnuc_0245 phosphoribosyltransferase YP_001797176.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001797177.1 KEGG: pnu:Pnuc_0247 hypothetical protein YP_001797178.1 KEGG: pnu:Pnuc_0248 hypothetical protein YP_001797179.1 KEGG: gdi:GDI2996 hypothetical protein YP_001797180.1 KEGG: pnu:Pnuc_0315 hypothetical protein YP_001797183.1 KEGG: bba:Bd1672 putative N-acetylglucosaminyltransferase YP_001797185.1 KEGG: sye:Syncc9902_0126 hypothetical protein YP_001797186.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: pnu:Pnuc_0253 dTDP-glucose 4,6-dehydratase YP_001797187.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: pnu:Pnuc_0254 dTDP-4-dehydrorhamnose reductase YP_001797188.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: pnu:Pnuc_0255 glucose-1-phosphate thymidylyltransferase YP_001797189.1 KEGG: pnu:Pnuc_0256 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_001797190.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: pnu:Pnuc_0257 lipopolysaccharide heptosyltransferase I YP_001797191.1 KEGG: pnu:Pnuc_0258 type I secretion outer membrane protein, TolC family YP_001797193.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001797194.1 KEGG: pnu:Pnuc_0260 hypothetical protein YP_001797195.1 KEGG: pnu:Pnuc_0262 tRNA (guanine-N(7)-)-methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: putative methyltransferase YP_001797196.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: pnu:Pnuc_0263 succinic semialdehyde dehydrogenase YP_001797197.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44; KEGG: pnu:Pnuc_0264 NusB antitermination factor YP_001797198.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001797199.1 TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: pnu:Pnuc_0266 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001797201.1 KEGG: pnu:Pnuc_0267 hypothetical protein YP_001797202.1 KEGG: pnu:Pnuc_0267 hypothetical protein YP_001797203.1 KEGG: pnu:Pnuc_0268 hypothetical protein YP_001797204.1 KEGG: pnu:Pnuc_0269 hypothetical protein YP_001797205.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: pnu:Pnuc_0270 riboflavin biosynthesis protein RibD YP_001797206.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001797207.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: pnu:Pnuc_0272 ExsB protein YP_001797208.1 TIGRFAM: tol-pal system protein YbgF; KEGG: pnu:Pnuc_0273 tetratricopeptide TPR_2 repeat protein YP_001797209.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: pnu:Pnuc_0274 OmpA/MotB domain protein YP_001797210.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001797211.1 TIGRFAM: TonB family protein; protein TolA; KEGG: pnu:Pnuc_0276 TonB, C-terminal domain YP_001797212.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: pnu:Pnuc_0277 biopolymer transport protein ExbD/TolR YP_001797213.1 TIGRFAM: protein TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: pnu:Pnuc_0278 MotA/TolQ/ExbB proton channel YP_001797214.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001797215.1 PFAM: ATP-cone domain protein; KEGG: pnu:Pnuc_0280 ATP-cone domain protein YP_001797216.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001797217.1 KEGG: pnu:Pnuc_0282 3-deoxy-D-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase YP_001797218.1 PFAM: protein of unknown function DUF343; KEGG: pnu:Pnuc_0283 protein of unknown function DUF343 YP_001797219.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001797220.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: pnu:Pnuc_0285 biopolymer transport protein ExbD/TolR YP_001797221.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: pnu:Pnuc_0286 MotA/TolQ/ExbB proton channel YP_001797222.1 KEGG: pnu:Pnuc_0287 exodeoxyribonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII large subunit; nucleic acid binding OB-fold tRNA/helicase-type YP_001797223.1 KEGG: syd:Syncc9605_0903 NHL repeat YP_001797224.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001797225.1 PFAM: protein of unknown function DUF520; KEGG: pnu:Pnuc_0290 protein of unknown function DUF520 YP_001797226.1 TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: pnu:Pnuc_0292 tyrosine recombinase XerD YP_001797227.1 PFAM: protein of unknown function DUF205; KEGG: pnu:Pnuc_0293 protein of unknown function DUF205 YP_001797228.1 KEGG: pnu:Pnuc_0294 membrane protein-like protein YP_001797233.1 PFAM: High potential iron-sulfur protein; Ergtoxin; KEGG: pnu:Pnuc_0296 high potential iron-sulfur protein YP_001797234.1 KEGG: pnu:Pnuc_0299 HPP family protein+B94 YP_001797235.1 KEGG: pnu:Pnuc_0300 hypothetical protein YP_001797236.1 KEGG: pnu:Pnuc_0301 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein YP_001797237.1 TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: tbd:Tbd_1881 alpha-D-glucose-1-phosphate cytidylyltransferase YP_001797238.1 TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; KEGG: eca:ECA1423 CDP-glucose 4,6-dehydratase YP_001797239.1 KEGG: ppf:Pput_1483 N-acetylneuraminic acid synthase, N-terminal domain YP_001797240.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rpa:RPA4051 possible oxo-acyl acyl carrier protein dehydrogenase YP_001797241.1 PFAM: 3-dehydroquinate synthase; KEGG: rpa:RPA4052 possible 3-dehydroquinate synthase YP_001797242.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: rpa:RPA4053 possible dTDPglucose 4,6-dehydratase YP_001797243.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rpa:RPA4054 possible acetolactate synthase large subunit YP_001797244.1 PFAM: GtrA family protein; KEGG: rpa:RPA4055 hypothetical protein YP_001797245.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: rpa:RPA4056 hypothetical protein YP_001797246.1 PFAM: glycosyl transferase family 2; KEGG: rpa:RPA4057 possible dolichol phosphate mannose synthase YP_001797248.1 KEGG: rpa:RPA4060 hypothetical protein YP_001797249.1 KEGG: rpa:RPA4063 hypothetical protein YP_001797250.1 KEGG: rpa:RPA4065 hypothetical protein YP_001797251.1 KEGG: rpa:RPA4064 hypothetical protein YP_001797252.1 KEGG: rpa:RPA4062 hypothetical protein YP_001797253.1 KEGG: tbd:Tbd_1883 hypothetical protein YP_001797254.1 PFAM: glycosyl transferase family 2; KEGG: net:Neut_0179 glycosyl transferase, family 2 YP_001797255.1 PFAM: glycosyl transferase family 4; KEGG: bam:Bamb_0767 glycosyl transferase, family 4 YP_001797257.1 KEGG: pnu:Pnuc_0355 extracellular ligand-binding receptor YP_001797258.1 KEGG: pnu:Pnuc_0359 hypothetical protein YP_001797259.1 PFAM: protein of unknown function DUF81; KEGG: pnu:Pnuc_0360 protein of unknown function DUF81 YP_001797260.1 PFAM: regulatory protein ArsR; KEGG: pnu:Pnuc_0793 regulatory protein, ArsR YP_001797261.1 KEGG: pnu:Pnuc_1566 hypothetical protein YP_001797262.1 KEGG: pnu:Pnuc_1566 hypothetical protein YP_001797263.1 PFAM: FMN-binding domain protein; KEGG: pnu:Pnuc_1564 FMN-binding domain protein YP_001797264.1 KEGG: pnu:Pnuc_0361 conserved hypothetical secreted protein YP_001797265.1 KEGG: pnu:Pnuc_0362 hypothetical protein YP_001797266.1 PFAM: DNA/RNA non-specific endonuclease; KEGG: pnu:Pnuc_0363 DNA/RNA non-specific endonuclease YP_001797267.1 PFAM: Lytic transglycosylase catalytic; KEGG: pnu:Pnuc_0364 lytic transglycosylase, catalytic YP_001797268.1 KEGG: pnu:Pnuc_0366 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type YP_001797269.1 PFAM: BLUF domain protein; KEGG: pnu:Pnuc_0367 BLUF domain protein YP_001797270.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001797271.1 PFAM: Lipocalin family protein; KEGG: pnu:Pnuc_0369 lipocalin family protein YP_001797273.1 KEGG: pnu:Pnuc_1533 hypothetical protein YP_001797274.1 KEGG: pnu:Pnuc_1533 hypothetical protein YP_001797275.1 KEGG: pnu:Pnuc_0374 hypothetical protein YP_001797276.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pnu:Pnuc_0375 pseudouridine synthase YP_001797277.1 PFAM: transcriptional coactivator/pterin dehydratase; KEGG: pnu:Pnuc_0376 transcriptional coactivator/pterin dehydratase YP_001797279.1 KEGG: pnu:Pnuc_0377 hypothetical protein YP_001797280.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: pnu:Pnuc_0379 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001797281.1 PFAM: dihydrofolate reductase region; KEGG: pnu:Pnuc_0380 dihydrofolate reductase YP_001797282.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001797283.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pnu:Pnuc_0382 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001797284.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pnu:Pnuc_0383 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001797285.1 KEGG: pnu:Pnuc_0385 hypothetical protein YP_001797286.1 PFAM: MoeA domain protein domain IV; KEGG: pnu:Pnuc_0386 molybdenum cofactor synthesis domain YP_001797287.1 KEGG: pnu:Pnuc_0387 molybdopterin-guanine dinucleotide biosynthesis protein A YP_001797288.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: pnu:Pnuc_0389 ribonuclease, Rne/Rng family YP_001797289.1 KEGG: pnu:Pnuc_0390 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001797290.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pnu:Pnuc_0391 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001797291.1 PFAM: peptidase S49; KEGG: pnu:Pnuc_0392 peptidase S49 YP_001797292.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pnu:Pnuc_0393 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001797293.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: pnu:Pnuc_0394 maf protein YP_001797294.1 PFAM: protein of unknown function DUF177; KEGG: pnu:Pnuc_0395 protein of unknown function DUF177 YP_001797295.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001797296.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001797297.1 KEGG: pnu:Pnuc_0398 3-oxoacyl-(acyl-carrier-protein) synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YP_001797298.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: pnu:Pnuc_0399 malonyl CoA-acyl carrier protein transacylase YP_001797299.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pnu:Pnuc_0400 3-oxoacyl-(acyl-carrier-protein) reductase YP_001797300.1 carries the fatty acid chain in fatty acid biosynthesis YP_001797301.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001797302.1 KEGG: pnu:Pnuc_0403 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001797303.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001797304.1 KEGG: pnu:Pnuc_0405 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein YP_001797305.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001797306.1 TIGRFAM: small GTP-binding protein; GTP-binding protein Era; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; KEGG: pnu:Pnuc_0407 GTP-binding protein Era YP_001797307.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001797308.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001797309.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: pnu:Pnuc_0411 glycoside hydrolase, family 3 domain protein YP_001797310.1 KEGG: pnu:Pnuc_0569 GCN5-related N-acetyltransferase YP_001797311.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001797312.1 KEGG: pnu:Pnuc_0414 hypothetical protein YP_001797313.1 KEGG: pnu:Pnuc_0415 excinuclease ABC, C subunit; TIGRFAM: excinuclease ABC, C subunit; PFAM: Excinuclease ABC C subunit domain protein; excinuclease ABC C subunit domain protein; UvrB/UvrC protein; SMART: Helix-hairpin-helix DNA-binding class 1 YP_001797314.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: pnu:Pnuc_0416 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001797315.1 KEGG: pnu:Pnuc_0418 SOS-response transcriptional repressor, LexA; TIGRFAM: LexA repressor; PFAM: LexA DNA-binding domain protein; peptidase S24 and S26 domain protein YP_001797316.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001797317.1 KEGG: pnu:Pnuc_0421 putative primosomal replication protein N, PriB YP_001797318.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001797319.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001797320.1 KEGG: rso:RSc1311 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SMART: AAA ATPase YP_001797322.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pnu:Pnuc_0429 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001797323.1 PFAM: polysaccharide deacetylase; KEGG: pnu:Pnuc_0430 polysaccharide deacetylase YP_001797324.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: pnu:Pnuc_0431 hypothetical protein YP_001797325.1 PFAM: formyl transferase domain protein; KEGG: pnu:Pnuc_0432 hypothetical protein YP_001797326.1 PFAM: glycosyl transferase family 2; KEGG: pnu:Pnuc_0433 glycosyl transferase, family 2 YP_001797327.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: pnu:Pnuc_0434 DegT/DnrJ/EryC1/StrS aminotransferase YP_001797328.1 PFAM: glycosyl transferase family 39; KEGG: pnu:Pnuc_0435 glycosyl transferase, family 39 YP_001797329.1 PFAM: protein of unknown function DUF498; KEGG: pnu:Pnuc_0436 protein of unknown function DUF498 YP_001797330.1 PFAM: aminotransferase class I and II; KEGG: pnu:Pnuc_0437 aminotransferase AlaT YP_001797331.1 PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: pnu:Pnuc_0438 homoserine dehydrogenase YP_001797332.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001797333.1 PFAM: MoeA domain protein domain I and II; KEGG: pnu:Pnuc_0440 molybdenum cofactor synthesis domain YP_001797334.1 KEGG: mms:mma_1315 molybdopterin converting factor subunit 1 YP_001797335.1 PFAM: molybdopterin biosynthesis MoaE protein; KEGG: pnu:Pnuc_0442 molybdopterin biosynthesis protein MoaE YP_001797336.1 PFAM: Excinuclease ABC C subunit domain protein; KEGG: pnu:Pnuc_0446 excinuclease ABC, C subunit domain protein YP_001797337.1 KEGG: pnu:Pnuc_0447 ATPase AAA-2 domain protein; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001797338.1 PFAM: histidine triad (HIT) protein; KEGG: pnu:Pnuc_1505 histidine triad (HIT) protein YP_001797339.1 KEGG: ddi:DDBDRAFT_0203031 hypothetical protein YP_001797342.1 KEGG: hch:HCH_00570 hypothetical protein YP_001797343.1 PFAM: Domain of unknown function DUF1841; KEGG: pnu:Pnuc_1500 hypothetical protein YP_001797344.1 KEGG: pnu:Pnuc_1499 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein YP_001797345.1 TIGRFAM: electron transport complex, RnfABCDGE type, B subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Fe-S cluster domain protein; KEGG: pnu:Pnuc_1498 electron transport complex, RnfABCDGE type, B subunit YP_001797346.1 TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein; KEGG: pnu:Pnuc_1497 polyhydroxyalkanoate depolymerase, intracellular YP_001797347.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001797348.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001797349.1 TIGRFAM: transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: pnu:Pnuc_1494 transcriptional regulator, BadM/Rrf2 family YP_001797350.1 TIGRFAM: cysteine desulfurase IscS; PFAM: aminotransferase class V; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: pnu:Pnuc_1493 cysteine desulfurase IscS YP_001797351.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: pnu:Pnuc_1492 FeS cluster assembly scaffold IscU YP_001797352.1 TIGRFAM: iron-sulfur cluster assembly protein IscA; iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: pnu:Pnuc_1491 iron-sulfur cluster assembly protein IscA YP_001797353.1 TIGRFAM: co-chaperone Hsc20; PFAM: heat shock protein DnaJ domain protein; HSC20 oligomerisation; KEGG: pnu:Pnuc_1490 co-chaperone Hsc20 YP_001797354.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001797355.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: pnu:Pnuc_1488 ferredoxin, 2Fe-2S type, ISC system YP_001797356.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001797357.1 PFAM: phosphoadenosine phosphosulfate reductase; KEGG: pnu:Pnuc_1481 adenylylsulfate reductase, thioredoxin dependent YP_001797358.1 KEGG: pnu:Pnuc_1481 adenylylsulfate reductase, thioredoxin dependent YP_001797359.1 KEGG: pnu:Pnuc_1480 protein of unknown function DUF81 YP_001797360.1 KEGG: pnu:Pnuc_1480 protein of unknown function DUF81 YP_001797362.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: pnu:Pnuc_1479 ferredoxin--NADP(+) reductase YP_001797363.1 PFAM: Disulphide bond formation protein DsbB; KEGG: pnu:Pnuc_1478 disulphide bond formation protein DsbB YP_001797364.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pnu:Pnuc_1476 cysteine synthase A YP_001797365.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001797366.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: pnu:Pnuc_1471 peptide chain release factor 2 YP_001797367.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: pnu:Pnuc_1470 single-stranded-DNA-specific exonuclease RecJ YP_001797368.1 KEGG: pnu:Pnuc_1469 hypothetical protein YP_001797369.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: pnu:Pnuc_1468 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001797370.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_1467 ABC transporter YP_001797371.1 PFAM: TatD-related deoxyribonuclease; KEGG: pnu:Pnuc_1466 TatD-related deoxyribonuclease YP_001797372.1 KEGG: pnu:Pnuc_1465 DNA internalization-related competence protein ComEC/Rec2 YP_001797373.1 KEGG: pnu:Pnuc_1464 hypothetical protein YP_001797374.1 KEGG: pnu:Pnuc_1462 hypothetical protein YP_001797375.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001797376.1 involved in methylation of ribosomal protein L3 YP_001797377.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001797378.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001797379.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain protein; KEGG: pnu:Pnuc_1457 chromosome segregation protein SMC YP_001797380.1 SMART: ZipA FtsZ-binding region; KEGG: pnu:Pnuc_1456 ZipA, C-terminal FtsZ-binding region YP_001797381.1 KEGG: pnu:Pnuc_1455 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: helix-hairpin-helix motif; BRCT domain protein; zinc-finger NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase OB-fold; NAD-dependent DNA ligase adenylation; SMART: Helix-hairpin-helix DNA-binding class 1; NAD-dependent DNA ligase YP_001797382.1 PFAM: NUDIX hydrolase; KEGG: rrj:RrIowa_1347 phosphohydrolase (MutT/NUDIX family protein) YP_001797383.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: pnu:Pnuc_1452 methionine aminopeptidase, type I YP_001797384.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001797385.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001797386.1 Catalyzes the phosphorylation of UMP to UDP YP_001797387.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001797388.1 KEGG: pnu:Pnuc_1447 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001797389.1 PFAM: phosphatidate cytidylyltransferase; KEGG: pnu:Pnuc_1446 phosphatidate cytidylyltransferase YP_001797390.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001797391.1 TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; KEGG: pnu:Pnuc_1444 putative membrane-associated zinc metalloprotease YP_001797392.1 TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: pnu:Pnuc_1443 surface antigen (D15) YP_001797393.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: pnu:Pnuc_1442 outer membrane chaperone Skp (OmpH) YP_001797394.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001797395.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001797396.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001797397.1 KEGG: pnu:Pnuc_1438 lipid-A-disaccharide synthase; TIGRFAM: lipid-A-disaccharide synthase; PFAM: glycosyl transferase family 19 YP_001797398.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001797399.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: pnu:Pnuc_1436 tRNA/rRNA methyltransferase (SpoU) YP_001797400.1 KEGG: pnu:Pnuc_1434 protein of unknown function DUF299 YP_001797401.1 KEGG: pnu:Pnuc_1434 protein of unknown function DUF299 YP_001797402.1 KEGG: pnu:Pnuc_1427 protein of unknown function DUF404 YP_001797403.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001797404.1 PFAM: cyclase/dehydrase; KEGG: pnu:Pnuc_1425 cyclase/dehydrase YP_001797405.1 PFAM: protein of unknown function UPF0125; KEGG: pnu:Pnuc_1424 protein of unknown function UPF0125 YP_001797406.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001797407.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001797408.1 PFAM: protein of unknown function DUF455; KEGG: pnu:Pnuc_1421 protein of unknown function DUF455 YP_001797409.1 KEGG: pnu:Pnuc_1420 radical SAM domain protein YP_001797410.1 KEGG: pnu:Pnuc_1419 hypothetical protein YP_001797411.1 KEGG: pnu:Pnuc_1419 hypothetical protein YP_001797412.1 KEGG: pnu:Pnuc_1419 hypothetical protein YP_001797413.1 KEGG: pnu:Pnuc_1419 hypothetical protein YP_001797414.1 KEGG: pnu:Pnuc_1419 hypothetical protein YP_001797415.1 PFAM: Radical SAM domain protein; KEGG: pnu:Pnuc_1418 radical SAM domain protein YP_001797416.1 KEGG: pnu:Pnuc_1417 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001797417.1 KEGG: pnu:Pnuc_1417 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001797418.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: pnu:Pnuc_1416 CMP/dCMP deaminase, zinc-binding YP_001797419.1 PFAM: peptidase U61 LD-carboxypeptidase A; KEGG: pnu:Pnuc_1415 muramoyltetrapeptide carboxypeptidase YP_001797420.1 KEGG: pnu:Pnuc_1414 SOUL heme-binding protein YP_001797421.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: pnu:Pnuc_1412 phosphoesterase, PA-phosphatase related YP_001797422.1 PFAM: glycosyl transferase family 9; KEGG: pnu:Pnuc_1411 glycosyl transferase, family 9 YP_001797423.1 KEGG: pnu:Pnuc_1410 hypothetical protein YP_001797424.1 KEGG: pnu:Pnuc_1409 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family-like protein YP_001797425.1 KEGG: pnu:Pnuc_1408 hypothetical protein YP_001797426.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; KEGG: pnu:Pnuc_1407 heavy metal translocating P-type ATPase YP_001797427.1 KEGG: pnu:Pnuc_1407 heavy metal translocating P-type ATPase YP_001797428.1 KEGG: pnu:Pnuc_1406 heavy metal transport/detoxification protein YP_001797429.1 PFAM: protein of unknown function DUF47; KEGG: pnu:Pnuc_1405 protein of unknown function DUF47 YP_001797430.1 PFAM: phosphate transporter; KEGG: pnu:Pnuc_1404 phosphate transporter YP_001797431.1 PFAM: protein of unknown function DUF59; KEGG: pnu:Pnuc_1403 protein of unknown function DUF59 YP_001797432.1 KEGG: pnu:Pnuc_1402 hypothetical protein YP_001797433.1 KEGG: pnu:Pnuc_1402 hypothetical protein YP_001797434.1 KEGG: pnu:Pnuc_1401 hypothetical protein YP_001797435.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pnu:Pnuc_1397 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001797436.1 KEGG: pnu:Pnuc_1396 hypothetical protein YP_001797437.1 KEGG: pnu:Pnuc_1395 formate dehydrogenase, gamma subunit YP_001797438.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_1393 ABC transporter YP_001797439.1 KEGG: pnu:Pnuc_1392 binding-protein-dependent transport systems inner membrane component YP_001797440.1 KEGG: pnu:Pnuc_1392 binding-protein-dependent transport systems inner membrane component YP_001797441.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: pnu:Pnuc_1391 endonuclease/exonuclease/phosphatase YP_001797442.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001797443.1 KEGG: pnu:Pnuc_1389 L-carnitine dehydratase/bile acid-inducible protein F YP_001797444.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pnu:Pnuc_1388 acyl-CoA dehydrogenase domain protein YP_001797445.1 KEGG: pnu:Pnuc_1387 hypothetical protein YP_001797446.1 TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pnu:Pnuc_1386 3-hydroxybutyrate dehydrogenase YP_001797447.1 KEGG: pnu:Pnuc_1384 hypothetical protein YP_001797448.1 KEGG: pnu:Pnuc_1378 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001797449.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pnu:Pnuc_1374 NADH:flavin oxidoreductase/NADH oxidase YP_001797451.1 KEGG: pnu:Pnuc_1373 cytochrome b561 YP_001797452.1 KEGG: pnu:Pnuc_1373 cytochrome b561 YP_001797453.1 KEGG: pnu:Pnuc_1372 hypothetical protein YP_001797454.1 KEGG: reu:Reut_B4705 hypothetical protein YP_001797455.1 PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: pnu:Pnuc_1364 protein of unknown function DUF6, transmembrane YP_001797456.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; KEGG: pnu:Pnuc_1363 carbohydrate kinase, YjeF related protein YP_001797457.1 SMART: extracellular solute-binding protein family 3; KEGG: pnu:Pnuc_1361 extracellular solute-binding protein, family 3 YP_001797458.1 KEGG: pnu:Pnuc_1360 hypothetical protein YP_001797459.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_1359 conserved hypothetical protein 730 YP_001797460.1 KEGG: pnu:Pnuc_1358 hypothetical protein YP_001797461.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; KEGG: pnu:Pnuc_1357 HI0933 family protein YP_001797463.1 PFAM: conserved hypothetical protein; KEGG: pol:Bpro_3470 uncharacterized protein UPF0065 YP_001797464.1 KEGG: pnu:Pnuc_1354 hypothetical protein YP_001797465.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_1353 hypothetical protein YP_001797466.1 KEGG: pnu:Pnuc_1351 fumarylacetoacetate (FAA) hydrolase YP_001797467.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_1349 uncharacterized protein UPF0065 YP_001797468.1 KEGG: pnu:Pnuc_1348 hypothetical protein YP_001797469.1 KEGG: pnu:Pnuc_1347 protein of unknown function DUF1330 YP_001797470.1 TIGRFAM: selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: pnu:Pnuc_1345 selenide, water dikinase YP_001797471.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pnu:Pnuc_1344 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001797472.1 KEGG: pnu:Pnuc_1341 hypothetical protein YP_001797473.1 PFAM: thioesterase superfamily protein; KEGG: pnu:Pnuc_1340 thioesterase superfamily protein YP_001797474.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pnu:Pnuc_1339 GCN5-related N-acetyltransferase YP_001797475.1 KEGG: pnu:Pnuc_1338 hypothetical protein YP_001797476.1 PFAM: TOBE domain protein; KEGG: pnu:Pnuc_1337 TOBE domain protein YP_001797477.1 KEGG: pnu:Pnuc_1336 putative sulfate transport system substrate-binding protein YP_001797479.1 KEGG: pnu:Pnuc_1335 transcriptional regulator of molybdate metabolism, LysR family YP_001797480.1 KEGG: pnu:Pnuc_1335 transcriptional regulator of molybdate metabolism, LysR family YP_001797481.1 KEGG: pnu:Pnuc_1333 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001797482.1 KEGG: pnu:Pnuc_1333 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001797483.1 PFAM: Negative transcriptional regulator; KEGG: pnu:Pnuc_1332 FMN-binding negative transcriptional regulator YP_001797484.1 PFAM: FeoA family protein; KEGG: pnu:Pnuc_1330 FeoA family protein YP_001797485.1 TIGRFAM: ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; KEGG: pnu:Pnuc_1329 ferrous iron transport protein B YP_001797486.1 KEGG: tbd:Tbd_0840 putative cytochrome c5 YP_001797487.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_1323 uncharacterized protein UPF0065 YP_001797488.1 KEGG: pnu:Pnuc_1322 hypothetical protein YP_001797489.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001797490.1 KEGG: pnu:Pnuc_1315 hypothetical protein YP_001797491.1 KEGG: pnu:Pnuc_1314 hypothetical protein YP_001797492.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: pnu:Pnuc_1313 membrane lipoprotein lipid attachment site YP_001797493.1 KEGG: pnu:Pnuc_1312 hypothetical protein YP_001797494.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: pnu:Pnuc_1311 MATE efflux family protein YP_001797495.1 KEGG: pnu:Pnuc_1310 putative inner membrane transmembrane protein YP_001797496.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001797497.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001797498.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pnu:Pnuc_1307 thioredoxin YP_001797499.1 KEGG: pnu:Pnuc_1306 inactivated superfamily I helicase-like protein YP_001797500.1 PFAM: UvrD/REP helicase; KEGG: pnu:Pnuc_1305 UvrD/REP helicase YP_001797501.1 KEGG: ajs:Ajs_3338 hypothetical protein YP_001797503.1 KEGG: pnu:Pnuc_0700 DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase YP_001797504.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_0701 conserved hypothetical protein 103 YP_001797505.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001797506.1 PFAM: Carbohydrate-selective porin OprB; KEGG: pnu:Pnuc_0703 carbohydrate-selective porin OprB YP_001797507.1 PFAM: outer membrane efflux protein; KEGG: pnu:Pnuc_1302 outer membrane efflux protein YP_001797508.1 KEGG: pnu:Pnuc_1301 efflux transporter, RND family, MFP subunit YP_001797509.1 KEGG: pnu:Pnuc_1298 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001797510.1 PFAM: peptidoglycan-binding LysM; peptidase M23; KEGG: pnu:Pnuc_1297 peptidase M23B YP_001797511.1 TIGRFAM: RNA methyltransferase, TrmA family; PFAM: protein of unknown function Met10; (Uracil-5)-methyltransferase; KEGG: pnu:Pnuc_1295 RNA methyltransferase, TrmA family YP_001797512.1 PFAM: protein of unknown function UPF0005; KEGG: pnu:Pnuc_1294 protein of unknown function UPF0005 YP_001797513.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001797514.1 TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein; KEGG: pnu:Pnuc_1292 radical SAM enzyme, Cfr family YP_001797515.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001797516.1 KEGG: pnu:Pnuc_1290 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein YP_001797517.1 KEGG: pnu:Pnuc_1289 hypothetical protein YP_001797518.1 TIGRFAM: outer membrane assembly lipoprotein YfgL; PFAM: Pyrrolo-quinoline quinone; KEGG: pnu:Pnuc_1288 pyrrolo-quinoline quinone YP_001797519.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001797520.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein core; KEGG: pnu:Pnuc_1286 RNA chaperone Hfq YP_001797522.1 KEGG: pnu:Pnuc_1285 GTP-binding protein, HSR1-related YP_001797523.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: pnu:Pnuc_1284 HflK protein YP_001797524.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: pnu:Pnuc_1283 HflC protein YP_001797525.1 PFAM: tRNA synthetase class II (G H P and S); KEGG: pnu:Pnuc_1282 tRNA synthetase, class II (G, H, P and S) YP_001797526.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001797527.1 KEGG: pnu:Pnuc_1280 malate synthase G YP_001797528.1 KEGG: pnu:Pnuc_1279 hypothetical protein YP_001797529.1 KEGG: pnu:Pnuc_1278 hypothetical protein YP_001797530.1 KEGG: pnu:Pnuc_1277 major facilitator superfamily MFS_1 YP_001797531.1 KEGG: pnu:Pnuc_1272 amino acid permease-associated region YP_001797532.1 KEGG: pnu:Pnuc_1271 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; Cold-shock protein DNA-binding; RNA binding S1 domain protein; Ribonuclease B OB region domain; SMART: Cold shock protein YP_001797533.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: pnu:Pnuc_1270 RNA methyltransferase, TrmH family, group 3 YP_001797534.1 KEGG: pnu:Pnuc_1269 hypothetical protein YP_001797535.1 KEGG: pnu:Pnuc_1265 transaldolase B; TIGRFAM: transaldolase; PFAM: transaldolase YP_001797536.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001797537.1 PFAM: Fe(II) trafficking protein YggX; KEGG: pnu:Pnuc_1263 hypothetical protein YP_001797538.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001797539.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: cytochrome d1 heme region; KEGG: pnu:Pnuc_1260 40-residue YVTN family beta-propeller repeat protein YP_001797540.1 KEGG: pnu:Pnuc_1257 putative transmembrane protein YP_001797541.1 PFAM: molybdopterin binding domain; KEGG: pnu:Pnuc_1256 molybdopterin binding domain YP_001797543.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: pnu:Pnuc_1255 glutamine synthetase, type I YP_001797544.1 PFAM: response regulator receiver; KEGG: pnu:Pnuc_1253 nitrogen metabolism transcriptional regulator, NtrC, fis family YP_001797545.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: pnu:Pnuc_1252 exodeoxyribonuclease III Xth YP_001797546.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: pnu:Pnuc_0730 oligopeptidase A YP_001797547.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001797548.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: pnu:Pnuc_0732 response regulator receiver protein YP_001797549.1 PFAM: ATP-binding region ATPase domain protein; KEGG: pnu:Pnuc_0733 multi-sensor signal transduction histidine kinase YP_001797550.1 KEGG: pnu:Pnuc_1578 arsenical-resistance protein YP_001797551.1 PFAM: conserved hypothetical protein; KEGG: reh:H16_A0198 probable extra-cytoplasmic solute receptor YP_001797552.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: pnu:Pnuc_1210 glutamate synthase (NADPH) YP_001797553.1 KEGG: pnu:Pnuc_1209 hypothetical protein YP_001797554.1 KEGG: pnu:Pnuc_2068 hypothetical protein YP_001797555.1 KEGG: pnu:Pnuc_1208 hypothetical protein YP_001797556.1 PFAM: regulatory protein LuxR; Helix-turn-helix type 11 domain protein; SMART: PAC repeat-containing protein; KEGG: pfo:Pfl_4555 response regulator receiver signal transduction histidine kinase YP_001797557.1 PFAM: ATP-binding region ATPase domain protein; KEGG: lpc:LPC_0355 sensor histidine kinase YP_001797558.1 KEGG: pca:Pcar_1011 two component signal transduction sensor lacking kinase domain YP_001797559.1 KEGG: pnu:Pnuc_1165 diguanylate cyclase YP_001797562.1 KEGG: pfl:PFL_5287 type IV pilus protein PilA YP_001797563.1 KEGG: bba:Bd1290 fimbrial protein PilA YP_001797564.1 KEGG: mta:Moth_1550 peptidase A24A-like YP_001797567.1 KEGG: gme:Gmet_0965 N-terminal methylation YP_001797568.1 KEGG: aeh:Mlg_0860 Tfp pilus assembly protein PilX-like protein YP_001797570.1 KEGG: pub:SAR11_0068 type II secretion PilY1 YP_001797571.1 KEGG: shm:Shewmr7_3032 type IV pilin biogenesis protein, putative YP_001797572.1 KEGG: pub:SAR11_0068 type II secretion PilY1 YP_001797573.1 PFAM: Fimbrial assembly family protein; KEGG: pub:SAR11_0063 type II secretion YP_001797574.1 KEGG: pub:SAR11_0062 type 4 fimbrial biogenesis protein PilO YP_001797575.1 PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB short domain; KEGG: pub:SAR11_0060 type II secretion PilQ YP_001797577.1 PFAM: type II secretion system protein; KEGG: pub:SAR11_0058 type II secretion system PilC YP_001797579.1 PFAM: dihydrouridine synthase DuS; KEGG: pnu:Pnuc_1177 tRNA-dihydrouridine synthase A YP_001797580.1 KEGG: pnu:Pnuc_1164 hypothetical protein YP_001797581.1 PFAM: gamma-glutamyltranspeptidase; KEGG: pnu:Pnuc_1163 gamma-glutamyltransferase YP_001797582.1 PFAM: LrgB family protein; KEGG: pnu:Pnuc_1161 LrgB family protein YP_001797583.1 KEGG: pnu:Pnuc_1151 hypothetical protein YP_001797584.1 PFAM: peptidase S45 penicillin amidase; KEGG: pnu:Pnuc_1150 penicillin amidase YP_001797585.1 KEGG: pnu:Pnuc_1144 hypothetical protein YP_001797586.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: pnu:Pnuc_1143 biopolymer transport protein ExbD/TolR YP_001797587.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: pnu:Pnuc_1142 MotA/TolQ/ExbB proton channel YP_001797588.1 TIGRFAM: TonB family protein; KEGG: pnu:Pnuc_1141 TonB family protein YP_001797589.1 KEGG: pnu:Pnuc_1140 glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/hydantoin racemase YP_001797590.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: pnu:Pnuc_1139 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit YP_001797591.1 TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: pnu:Pnuc_1138 acetate--CoA ligase YP_001797592.1 KEGG: rha:RHA1_ro04172 probable arylsulfatase YP_001797593.1 KEGG: rha:RHA1_ro04172 probable arylsulfatase YP_001797594.1 KEGG: rha:RHA1_ro04172 probable arylsulfatase YP_001797595.1 KEGG: pnu:Pnuc_1115 YciI-like protein YP_001797596.1 KEGG: pnu:Pnuc_1110 NADH dehydrogenase (quinone) YP_001797597.1 KEGG: pnu:Pnuc_1109 formate dehydrogenase, alpha subunit YP_001797598.1 KEGG: pnu:Pnuc_1106 L-aspartate oxidase; TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein YP_001797599.1 KEGG: pnu:Pnuc_1104 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001797600.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001797602.1 KEGG: pnu:Pnuc_1094 polypeptide-transport-associated domain protein, ShlB-type YP_001797603.1 KEGG: mms:mma_1544 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001797605.1 KEGG: pnu:Pnuc_1149 filamentous haemagglutinin family outer membrane protein YP_001797606.1 KEGG: azc:AZC_1915 hypothetical protein YP_001797607.1 KEGG: mmw:Mmwyl1_3062 filamentous haemagglutinin family outer membrane protein YP_001797608.1 KEGG: nar:Saro_0424 hypothetical protein YP_001797609.1 KEGG: gbe:GbCGDNIH1_1135 hemagglutinin-related protein YP_001797610.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pnu:Pnuc_1092 phosphomannomutase YP_001797611.1 PFAM: phosphoglucose isomerase (PGI); KEGG: pnu:Pnuc_1091 glucose-6-phosphate isomerase YP_001797612.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: pnu:Pnuc_0573 multiple antibiotic resistance (MarC)-related protein YP_001797613.1 KEGG: pnu:Pnuc_1082 putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001797614.1 KEGG: pnu:Pnuc_1081 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family YP_001797615.1 Essential for recycling GMP and indirectly, cGMP YP_001797616.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001797617.1 KEGG: pnu:Pnuc_1076 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region YP_001797618.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: pnu:Pnuc_1075 transcription elongation factor GreB YP_001797620.1 KEGG: pnu:Pnuc_1074 protein of unknown function DUF140 YP_001797621.1 PFAM: protein of unknown function DUF140; KEGG: pnu:Pnuc_1074 protein of unknown function DUF140 YP_001797622.1 KEGG: pnu:Pnuc_1073 ABC transporter YP_001797623.1 KEGG: pnu:Pnuc_1068 protein of unknown function DUF214 YP_001797624.1 KEGG: pnu:Pnuc_1068 protein of unknown function DUF214 YP_001797625.1 PFAM: RDD domain containing protein; KEGG: pnu:Pnuc_1067 RDD domain containing protein YP_001797626.1 KEGG: pnu:Pnuc_1066 hypothetical protein YP_001797627.1 KEGG: pnu:Pnuc_1065 putative transmembrane protein YP_001797628.1 KEGG: pnu:Pnuc_1064 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001797629.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pnu:Pnuc_1063 acetolactate synthase, large subunit, biosynthetic type YP_001797630.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001797631.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001797632.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001797633.1 KEGG: pnu:Pnuc_1059 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001797634.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001797635.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001797636.1 KEGG: pnu:Pnuc_1055 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein YP_001797637.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001797638.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: pnu:Pnuc_1052 preprotein translocase, SecG subunit YP_001797639.1 Catalyzes the transfer of electrons from NADH to quinone YP_001797640.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001797641.1 KEGG: pnu:Pnuc_1049 NADH (or F420H2) dehydrogenase, subunit C; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit YP_001797642.1 Catalyzes the transfer of electrons from NADH to quinone YP_001797643.1 TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: pnu:Pnuc_1047 NADH-quinone oxidoreductase, E subunit YP_001797644.1 KEGG: pnu:Pnuc_1046 NADH-quinone oxidoreductase, F subunit; TIGRFAM: NADH-quinone oxidoreductase, F subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit YP_001797645.1 TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: ferredoxin; molybdopterin oxidoreductase; KEGG: pnu:Pnuc_1045 NADH-quinone oxidoreductase, chain G YP_001797646.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: pnu:Pnuc_1044 respiratory-chain NADH dehydrogenase, subunit 1 YP_001797647.1 Catalyzes the transfer of electrons from NADH to quinone YP_001797648.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; KEGG: pnu:Pnuc_1042 NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_001797649.1 PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: pnu:Pnuc_1041 NADH-ubiquinone oxidoreductase, chain 4L YP_001797650.1 KEGG: pnu:Pnuc_1040 proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I) YP_001797651.1 KEGG: pnu:Pnuc_1039 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001797652.1 KEGG: pnu:Pnuc_1038 proton-translocating NADH-quinone oxidoreductase, chain N; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001797653.1 PFAM: NUDIX hydrolase; KEGG: pnu:Pnuc_1037 NUDIX hydrolase YP_001797654.1 KEGG: pnu:Pnuc_1036 protein of unknown function DUF1178 YP_001797655.1 KEGG: pnu:Pnuc_1034 NADH:flavin oxidoreductase/NADH oxidase YP_001797656.1 KEGG: pnu:Pnuc_1028 tartrate dehydrogenase YP_001797657.1 KEGG: pnu:Pnuc_1027 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease YP_001797658.1 KEGG: pnu:Pnuc_1026 acriflavin resistance protein YP_001797659.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001797660.1 PFAM: Methyltransferase type 11; KEGG: pnu:Pnuc_1023 methyltransferase type 11 YP_001797661.1 KEGG: pnu:Pnuc_1022 hydroxyacylglutathione hydrolase; TIGRFAM: hydroxyacylglutathione hydrolase; PFAM: beta-lactamase domain protein YP_001797662.1 KEGG: pnu:Pnuc_1022 hydroxyacylglutathione hydrolase YP_001797663.1 KEGG: pnu:Pnuc_1020 propionate--CoA ligase YP_001797664.1 TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: pnu:Pnuc_1019 carbamoyl-phosphate synthase, small subunit YP_001797665.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001797666.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: pnu:Pnuc_1017 transcription elongation factor GreA YP_001797667.1 KEGG: pnu:Pnuc_1016 conserved hypothetical membrane spanning protein YP_001797668.1 PFAM: protein of unknown function UPF0044; KEGG: pnu:Pnuc_1015 protein of unknown function UPF0044 YP_001797669.1 PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: pnu:Pnuc_1014 ribosomal RNA methyltransferase RrmJ/FtsJ YP_001797670.1 KEGG: pnu:Pnuc_1013 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; peptidase M41 FtsH extracellular; SMART: AAA ATPase YP_001797671.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001797672.1 KEGG: pnu:Pnuc_1010 TonB-dependent receptor YP_001797673.1 PFAM: TonB-dependent receptor plug; KEGG: pnu:Pnuc_1010 TonB-dependent receptor YP_001797674.1 KEGG: pnu:Pnuc_1009 hypothetical protein YP_001797675.1 KEGG: pnu:Pnuc_0986 hypothetical protein YP_001797676.1 KEGG: pnu:Pnuc_0985 putative lipoprotein YP_001797678.1 PFAM: FAD linked oxidase domain protein; KEGG: pnu:Pnuc_0982 FAD linked oxidase domain protein YP_001797679.1 KEGG: pnu:Pnuc_0981 membrane protein-like protein YP_001797680.1 TIGRFAM: flavoprotein WrbA; PFAM: flavodoxin/nitric oxide synthase; KEGG: pnu:Pnuc_0980 flavodoxin/nitric oxide synthase YP_001797681.1 KEGG: pnu:Pnuc_0979 putative ribonuclease BN YP_001797682.1 KEGG: pnu:Pnuc_0979 putative ribonuclease BN YP_001797683.1 PFAM: CBS domain containing protein; KEGG: pnu:Pnuc_0978 CBS domain containing protein YP_001797684.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001797685.1 PFAM: major facilitator superfamily MFS_1; KEGG: pnu:Pnuc_0976 major facilitator superfamily MFS_1 YP_001797686.1 KEGG: pnu:Pnuc_0975 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001797687.1 PFAM: BolA family protein; KEGG: pnu:Pnuc_0974 BolA family protein YP_001797688.1 Involved in cell division; probably involved in intracellular septation YP_001797689.1 PFAM: Methionine sulfoxide reductase B; KEGG: pnu:Pnuc_0972 methionine-R-sulfoxide reductase YP_001797690.1 KEGG: pnu:Pnuc_0971 protein of unknown function UPF0061 YP_001797691.1 PFAM: protein of unknown function UPF0061; KEGG: pnu:Pnuc_0971 protein of unknown function UPF0061 YP_001797692.1 KEGG: pnu:Pnuc_0970 thioesterase superfamily protein YP_001797693.1 PFAM: protein of unknown function DUF833; KEGG: pnu:Pnuc_0969 protein of unknown function DUF833 YP_001797694.1 KEGG: pnu:Pnuc_0968 glycine cleavage T protein (aminomethyl transferase) YP_001797695.1 PFAM: aminodeoxychorismate lyase; KEGG: pnu:Pnuc_0967 aminodeoxychorismate lyase YP_001797696.1 PFAM: thymidylate kinase; KEGG: pnu:Pnuc_0966 dTMP kinase YP_001797697.1 KEGG: pnu:Pnuc_0965 DNA-directed DNA polymerase YP_001797698.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: pnu:Pnuc_0964 hydrolase, TatD family YP_001797699.1 KEGG: pnu:Pnuc_0962 ion transport 2 domain protein YP_001797700.1 KEGG: pnu:Pnuc_0961 hypothetical protein YP_001797701.1 KEGG: pnu:Pnuc_0961 hypothetical protein YP_001797702.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: pnu:Pnuc_0960 HNH endonuclease YP_001797703.1 PFAM: protein of unknown function UPF0227; KEGG: pnu:Pnuc_0959 protein of unknown function UPF0227 YP_001797704.1 KEGG: pol:Bpro_4562 hydroxypyruvate isomerase YP_001797705.1 KEGG: pol:Bpro_4562 hydroxypyruvate isomerase YP_001797706.1 KEGG: dac:Daci_2118 hydroxypyruvate isomerase YP_001797707.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001797708.1 PFAM: Septum formation initiator; KEGG: pnu:Pnuc_0948 septum formation initiator YP_001797709.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001797710.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001797711.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001797712.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001797713.1 PFAM: Spermine synthase; KEGG: pnu:Pnuc_0941 hypothetical protein YP_001797714.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001797715.1 PFAM: ABC transporter; KEGG: pnu:Pnuc_0939 ABC transporter YP_001797716.1 KEGG: pnu:Pnuc_0938 arylesterase YP_001797717.1 KEGG: pnu:Pnuc_0937 hypothetical protein YP_001797718.1 KEGG: pnu:Pnuc_0936 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001797719.1 binds and unfolds substrates as part of the ClpXP protease YP_001797720.1 KEGG: pnu:Pnuc_0934 ATP-dependent Clp protease, proteolytic subunit ClpP; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: peptidase S14 ClpP YP_001797721.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001797722.1 KEGG: pnu:Pnuc_0931 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase YP_001797723.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: pnu:Pnuc_0930 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001797724.1 KEGG: pnu:Pnuc_0929 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001797725.1 KEGG: pnu:Pnuc_0928 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3 YP_001797726.1 catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA YP_001797727.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001797728.1 TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR; PFAM: PHB accumulation regulatory domain protein; PHA accumulation regulator DNA-binding protein; KEGG: pnu:Pnuc_0925 polyhydroxyalkonate synthesis repressor, PhaR YP_001797729.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pnu:Pnuc_0924 3-ketoacyl-(acyl-carrier-protein) reductase YP_001797731.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: pnu:Pnuc_0923 poly(R)-hydroxyalkanoic acid synthase, class I YP_001797732.1 PFAM: protein of unknown function DUF152; KEGG: pnu:Pnuc_0922 protein of unknown function DUF152 YP_001797733.1 KEGG: pnu:Pnuc_0921 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001797734.1 KEGG: pnu:Pnuc_0920 putative transmembrane protein YP_001797735.1 KEGG: pnu:Pnuc_0919 alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein YP_001797736.1 PFAM: major facilitator superfamily MFS_1; KEGG: pnu:Pnuc_0918 hypothetical protein YP_001797737.1 KEGG: pnu:Pnuc_0917 hypothetical protein YP_001797738.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pnu:Pnuc_0916 ribosomal-protein-alanine acetyltransferase YP_001797739.1 PFAM: peptidase M22 glycoprotease; KEGG: pnu:Pnuc_0915 peptidase M22, glycoprotease YP_001797740.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pnu:Pnuc_0914 lactoylglutathione lyase YP_001797741.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: pnu:Pnuc_0913 acetyl-CoA carboxylase, biotin carboxylase YP_001797742.1 PFAM: carboxyl transferase; KEGG: pnu:Pnuc_0912 carboxyl transferase YP_001797743.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_001797744.1 MDM; functions in conversion of succinate to propionate YP_001797745.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: pnu:Pnuc_0909 transcriptional regulator, GntR family YP_001797746.1 PFAM: cytochrome c class I; KEGG: pnu:Pnuc_0908 cytochrome c, class I YP_001797747.1 KEGG: pnu:Pnuc_0907 putative periplasmic cytochrome type-c oxidoreductase signal peptide protein YP_001797748.1 KEGG: pnu:Pnuc_0906 ATPase associated with various cellular activities, AAA_5 YP_001797749.1 PFAM: Endoribonuclease L-PSP; KEGG: pnu:Pnuc_0904 endoribonuclease L-PSP YP_001797750.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001797751.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001797752.1 PFAM: NUDIX hydrolase; KEGG: pnu:Pnuc_0897 NUDIX hydrolase YP_001797753.1 PFAM: FAD dependent oxidoreductase; KEGG: pnu:Pnuc_0895 FAD dependent oxidoreductase YP_001797754.1 PFAM: thiazole biosynthesis family protein; KEGG: pnu:Pnuc_0893 thiazole synthase YP_001797755.1 KEGG: pnu:Pnuc_0892 thiamine-phosphate pyrophosphorylase YP_001797756.1 KEGG: pnu:Pnuc_2043 alpha/beta hydrolase fold YP_001797757.1 PFAM: peptidase U32; KEGG: pnu:Pnuc_0887 peptidase U32 YP_001797758.1 KEGG: cvi:CV_3350 hypothetical protein YP_001797759.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: pnu:Pnuc_1866 phospholipid/glycerol acyltransferase YP_001797760.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: reh:H16_A0293 putative 2-nitropropane dioxygenase YP_001797761.1 PFAM: AMP-dependent synthetase and ligase; KEGG: pnu:Pnuc_0883 AMP-dependent synthetase and ligase YP_001797762.1 KEGG: pnu:Pnuc_0562 hypothetical protein YP_001797763.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: rso:RSc0473 putative acyl-CoA dehydrogenase oxidoreductase protein YP_001797764.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: reu:Reut_A0447 enoyl-CoA hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001797765.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: reu:Reut_A0448 acetyl-CoA acetyltransferase YP_001797767.1 KEGG: reh:H16_A3181 hypothetical protein YP_001797768.1 PFAM: phosphoribosyltransferase; KEGG: pnu:Pnuc_0881 adenine phosphoribosyltransferase YP_001797769.1 KEGG: pnu:Pnuc_0880 hypothetical protein YP_001797770.1 KEGG: pnu:Pnuc_0879 putative transmembrane protein YP_001797771.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: pnu:Pnuc_0878 protein of unknown function DUF883, ElaB YP_001797772.1 KEGG: pnu:Pnuc_0877 Smr protein/MutS2 YP_001797773.1 KEGG: dac:Daci_0797 hypothetical protein YP_001797775.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001797776.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; Protein of unkown function DUF1946 PP-loop ATpase; KEGG: pnu:Pnuc_0861 tRNA(Ile)-lysidine synthetase YP_001797777.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001797778.1 PFAM: HhH-GPD family protein; KEGG: pnu:Pnuc_0859 HhH-GPD family protein YP_001797779.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001797780.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pnu:Pnuc_0857 tetratricopeptide TPR_2 repeat protein YP_001797781.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: pnu:Pnuc_0856 peptidylprolyl isomerase YP_001797782.1 TIGRFAM: UDP-2,3-diacylglucosamine hydrolase; PFAM: metallophosphoesterase; KEGG: pnu:Pnuc_0855 UDP-2,3-diacylglucosamine hydrolase YP_001797783.1 PFAM: inositol monophosphatase; KEGG: pnu:Pnuc_0854 inositol monophosphatase YP_001797784.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: pnu:Pnuc_0853 RNA methyltransferase, TrmH family, group 1 YP_001797785.1 KEGG: pnu:Pnuc_0852 serine O-acetyltransferase YP_001797786.1 KEGG: pnu:Pnuc_0851 putative FkbP-type peptidyl-prolyl cis-trans isomerase YP_001797787.1 PFAM: Cupin 4 family protein; KEGG: pnu:Pnuc_0850 cupin 4 family protein YP_001797788.1 PFAM: NlpBDapX family lipoprotein; KEGG: pnu:Pnuc_0848 NlpBDapX family lipoprotein YP_001797789.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001797790.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001797791.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: pnu:Pnuc_0844 PHP C-terminal domain protein YP_001797792.1 PFAM: AFG1-family ATPase; KEGG: pnu:Pnuc_0843 AFG1-family ATPase YP_001797793.1 E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001797794.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: pnu:Pnuc_0841 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_001797795.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001797796.1 PFAM: thioesterase superfamily protein; KEGG: pnu:Pnuc_0837 thioesterase superfamily protein YP_001797797.1 KEGG: pnu:Pnuc_0836 putative transcriptional regulator, MerR family YP_001797798.1 KEGG: pnu:Pnuc_0836 putative transcriptional regulator, MerR family YP_001797799.1 TIGRFAM: integration host factor, alpha subunit; PFAM: histone family protein DNA-binding protein; KEGG: pnu:Pnuc_0835 integration host factor, alpha subunit YP_001797800.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001797801.1 TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG: pnu:Pnuc_0833 phenylalanyl-tRNA synthetase, alpha subunit YP_001797802.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001797803.1 PFAM: ribosomal protein L35; KEGG: pnu:Pnuc_0831 ribosomal protein L35 YP_001797804.1 TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3; KEGG: pnu:Pnuc_0830 translation initiation factor IF-3 YP_001797805.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001797806.1 PFAM: TGS domain protein; RelA/SpoT domain protein; KEGG: pnu:Pnuc_0828 (p)ppGpp synthetase I, SpoT/RelA YP_001797807.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: alpha/beta hydrolase fold; cation efflux protein; KEGG: pnu:Pnuc_0827 cation diffusion facilitator family transporter YP_001797808.1 KEGG: pnu:Pnuc_0826 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001797809.1 KEGG: pnu:Pnuc_0825 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001797810.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: pnu:Pnuc_0824 electron-transferring-flavoprotein dehydrogenase YP_001797811.1 KEGG: pnu:Pnuc_0822 protein of unknown function DUF482 YP_001797812.1 PFAM: protein of unknown function DUF1289; KEGG: pnu:Pnuc_0821 protein of unknown function DUF1289 YP_001797813.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pnu:Pnuc_0818 acyl-CoA dehydrogenase domain protein YP_001797814.1 TIGRFAM: tRNA 2-selenouridine synthase; SMART: Rhodanese domain protein; KEGG: pnu:Pnuc_0816 rhodanese domain protein YP_001797815.1 PFAM: protein of unknown function DUF442; KEGG: pnu:Pnuc_0814 protein of unknown function DUF442 YP_001797816.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: pnu:Pnuc_0812 protein of unknown function DUF395, YeeE/YedE YP_001797817.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: pnu:Pnuc_0811 protein of unknown function DUF395, YeeE/YedE YP_001797818.1 KEGG: pnu:Pnuc_0810 hypothetical protein YP_001797819.1 PFAM: beta-lactamase domain protein; KEGG: pnu:Pnuc_0809 beta-lactamase domain protein YP_001797820.1 PFAM: Domain of unknown function DUF1791; KEGG: pnu:Pnuc_0808 hypothetical protein YP_001797821.1 PFAM: 5'-Nucleotidase domain protein; KEGG: pnu:Pnuc_0807 5'-nucleotidase domain protein YP_001797822.1 KEGG: pnu:Pnuc_0806 hypothetical protein YP_001797823.1 KEGG: pnu:Pnuc_0805 hypothetical protein YP_001797824.1 PFAM: Sulphur oxidation protein SoxZ; KEGG: pnu:Pnuc_0804 sulfur oxidation protein (SoxZ) YP_001797825.1 KEGG: pnu:Pnuc_0803 twin-arginine translocation pathway signal YP_001797826.1 PFAM: cytochrome c class I; KEGG: pnu:Pnuc_0802 cytochrome c, class I YP_001797828.1 PFAM: High potential iron-sulfur protein; Ergtoxin; KEGG: pnu:Pnuc_0296 high potential iron-sulfur protein YP_001797829.1 PFAM: cyclic nucleotide-binding; KEGG: pnu:Pnuc_0796 cyclic nucleotide-binding protein YP_001797830.1 PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: pnu:Pnuc_0780 methyltransferase type 11 YP_001797831.1 catalyzes the conversion of O-succinylhomoserine into homocysteine YP_001797832.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001797833.1 PFAM: Colicin V production protein; KEGG: pnu:Pnuc_0777 colicin V production protein YP_001797834.1 PFAM: Sporulation domain protein; KEGG: pnu:Pnuc_0776 sporulation domain protein YP_001797835.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pnu:Pnuc_0775 FolC bifunctional protein YP_001797836.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit; KEGG: pnu:Pnuc_0774 acetyl-CoA carboxylase, carboxyl transferase, beta subunit YP_001797837.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001797838.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001797839.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: pnu:Pnuc_0771 phosphoribosylanthranilate isomerase YP_001797840.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001797841.1 KEGG: pnu:Pnuc_0769 Tfp pilus assembly protein FimV-like protein YP_001797842.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001797843.1 KEGG: pnu:Pnuc_0767 3-isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase YP_001797844.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001797845.1 KEGG: pnu:Pnuc_0765 hypothetical protein YP_001797846.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001797847.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001797848.1 PFAM: protein of unknown function DUF339; KEGG: pnu:Pnuc_0762 protein of unknown function DUF339 YP_001797849.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: pnu:Pnuc_0761 succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_001797850.1 KEGG: pnu:Pnuc_0760 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001797851.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: pnu:Pnuc_0759 succinate dehydrogenase, cytochrome b subunit YP_001797852.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: pnu:Pnuc_0758 succinate dehydrogenase, cytochrome b subunit YP_001797853.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: pnu:Pnuc_0757 transcriptional regulator, GntR family YP_001797854.1 catalyzes the oxidation of malate to oxaloacetate YP_001797855.1 KEGG: pnu:Pnuc_0755 hypothetical protein YP_001797856.1 KEGG: pnu:Pnuc_0754 hypothetical protein YP_001797857.1 PFAM: protein of unknown function DUF328; KEGG: pnu:Pnuc_0753 protein of unknown function DUF328 YP_001797858.1 KEGG: pnu:Pnuc_0752 aminotransferase, class I and II YP_001797859.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: pnu:Pnuc_0750 3-hydroxybutyryl-CoA dehydrogenase YP_001797860.1 KEGG: pnu:Pnuc_0749 hypothetical protein YP_001797861.1 KEGG: pnu:Pnuc_0748 recombination factor protein RarA YP_001797862.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: pnu:Pnuc_0746 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001797863.1 PFAM: Chorismate binding-like; KEGG: pnu:Pnuc_0745 anthranilate synthase component I and chorismate binding protein YP_001797864.1 KEGG: pnu:Pnuc_0745 anthranilate synthase component I and chorismate binding protein YP_001797865.1 PFAM: NUDIX hydrolase; KEGG: pnu:Pnuc_0744 NUDIX hydrolase YP_001797866.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001797867.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001797868.1 PFAM: dihydroorotate dehydrogenase; KEGG: pnu:Pnuc_0741 dihydroorotate oxidase YP_001797869.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; KEGG: pnu:Pnuc_0740 regulatory protein IclR YP_001797870.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: pnu:Pnuc_0739 peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 YP_001797871.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: pnu:Pnuc_0738 protein of unknown function DUF6, transmembrane YP_001797872.1 KEGG: pnu:Pnuc_0737 phasin family protein YP_001797873.1 KEGG: pnu:Pnuc_0737 phasin family protein YP_001797874.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: pnu:Pnuc_0736 dihydrolipoamide dehydrogenase YP_001797875.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: pnu:Pnuc_0735 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase YP_001797876.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001797877.1 KEGG: pnu:Pnuc_0733 multi-sensor signal transduction histidine kinase YP_001797878.1 TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; tRNA pseudouridine synthase B; KEGG: pnu:Pnuc_1225 tRNA pseudouridine synthase B YP_001797879.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001797880.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001797881.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001797882.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001797883.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pnu:Pnuc_1230 pseudouridine synthase YP_001797884.1 KEGG: pnu:Pnuc_1230 pseudouridine synthase YP_001797885.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: pnu:Pnuc_1231 putative transcriptional regulator YP_001797886.1 PFAM: Patatin; KEGG: pnu:Pnuc_1232 patatin YP_001797887.1 PFAM: NLP/P60 protein; KEGG: pnu:Pnuc_1233 NLP/P60 protein YP_001797888.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_1234 ABC transporter YP_001797889.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pnu:Pnuc_1235 binding-protein-dependent transport systems inner membrane component YP_001797890.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pnu:Pnuc_1236 binding-protein-dependent transport systems inner membrane component YP_001797891.1 PFAM: extracellular solute-binding protein family 5; KEGG: pnu:Pnuc_1237 extracellular solute-binding protein, family 5 YP_001797892.1 KEGG: pnu:Pnuc_1238 short-chain dehydrogenase/reductase SDR YP_001797893.1 PFAM: MmgE/PrpD family protein; KEGG: pnu:Pnuc_1242 MmgE/PrpD family protein YP_001797894.1 KEGG: pnu:Pnuc_1243 HpcH/HpaI aldolase YP_001797895.1 KEGG: pol:Bpro_0579 uncharacterized protein UPF0065 YP_001797896.1 KEGG: pnu:Pnuc_1245 hypothetical protein YP_001797897.1 KEGG: pnu:Pnuc_1246 BNR/Asp-box repeat protein YP_001797898.1 KEGG: pnu:Pnuc_1247 glycosyl transferase, family 39 YP_001797899.1 KEGG: pnu:Pnuc_0729 hypothetical protein YP_001797900.1 KEGG: eba:ebA1124 hypothetical protein YP_001797901.1 KEGG: pna:Pnap_2555 hypothetical protein YP_001797902.1 KEGG: vei:Veis_4017 hypothetical protein YP_001797903.1 KEGG: ajs:Ajs_1985 pirin domain protein YP_001797905.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: pnu:Pnuc_0723 heat shock protein DnaJ domain protein YP_001797906.1 KEGG: pnu:Pnuc_0722 hypothetical protein YP_001797907.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_0721 ABC transporter YP_001797908.1 PFAM: OmpW family protein; KEGG: pnu:Pnuc_0719 OmpW family protein YP_001797909.1 KEGG: pnu:Pnuc_0718 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001797910.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pnu:Pnuc_0717 FAD dependent oxidoreductase YP_001797911.1 PFAM: YaeQ family protein; KEGG: pnu:Pnuc_0716 YaeQ family protein YP_001797912.1 KEGG: pnu:Pnuc_0715 protein of unknown function DUF132 YP_001797914.1 PFAM: SlyX family protein; KEGG: pnu:Pnuc_0713 SlyX family protein YP_001797915.1 KEGG: pnu:Pnuc_0712 membrane protein of unknown function YP_001797916.1 KEGG: pnu:Pnuc_0711 AsmA family protein YP_001797917.1 KEGG: pnu:Pnuc_0711 AsmA family protein YP_001797918.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: pnu:Pnuc_0710 alkylphosphonate utilization operon protein PhnA YP_001797919.1 KEGG: pnu:Pnuc_0708 hypothetical protein YP_001797920.1 KEGG: pnu:Pnuc_0707 hypothetical protein YP_001797921.1 KEGG: syx:SynWH7803_0874 possible pectin lyase (parallel beta-helix repeat protein) YP_001797922.1 KEGG: syx:SynWH7803_0874 possible pectin lyase (parallel beta-helix repeat protein) YP_001797923.1 KEGG: syx:SynWH7803_0874 possible pectin lyase (parallel beta-helix repeat protein) YP_001797924.1 KEGG: pna:Pnap_2200 PAS/PAC sensor signal transduction histidine kinase YP_001797925.1 PFAM: histidine kinase A domain protein; KEGG: pnu:Pnuc_1596 integral membrane sensor signal transduction histidine kinase YP_001797926.1 PFAM: response regulator receiver; KEGG: pnu:Pnuc_1597 two component transcriptional regulator, winged helix family YP_001797927.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; KEGG: pnu:Pnuc_1598 phosphate uptake regulator, PhoU YP_001797928.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: pnu:Pnuc_1602 phosphate ABC transporter, periplasmic phosphate-binding protein YP_001797930.1 KEGG: pnu:Pnuc_2040 MltA-interacting MipA family protein YP_001797931.1 PFAM: MltA-interacting MipA family protein; KEGG: pnu:Pnuc_2040 MltA-interacting MipA family protein YP_001797932.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001797933.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: pnu:Pnuc_0691 outer membrane lipoprotein carrier protein LolA YP_001797934.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: pnu:Pnuc_0690 cell division FtsK/SpoIIIE YP_001797935.1 KEGG: pnu:Pnuc_0689 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001797936.1 PFAM: Inorganic pyrophosphatase; KEGG: pnu:Pnuc_0685 inorganic diphosphatase YP_001797937.1 KEGG: pnu:Pnuc_0684 NAD+ synthetase; TIGRFAM: NAD+ synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; NAD synthase YP_001797938.1 KEGG: pnu:Pnuc_0682 hypothetical protein YP_001797939.1 KEGG: pnu:Pnuc_0682 hypothetical protein YP_001797940.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001797941.1 PFAM: protein of unknown function DUF461; KEGG: pnu:Pnuc_0679 protein of unknown function DUF461 YP_001797942.1 KEGG: rfr:Rfer_2015 hypothetical protein YP_001797944.1 KEGG: azo:azo2157 conserved hypothetical secreted protein YP_001797945.1 KEGG: dvl:Dvul_1186 hypothetical protein YP_001797946.1 KEGG: hch:HCH_02842 hypothetical protein YP_001797947.1 KEGG: pnu:Pnuc_0675 conserved hypothetical secreted protein YP_001797948.1 PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: pnu:Pnuc_0669 inositol phosphatase/fructose-1,6-bisphosphatase YP_001797949.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: pnu:Pnuc_0668 aminopeptidase N YP_001797950.1 KEGG: pnu:Pnuc_0667 protein of unknown function UPF0016 YP_001797951.1 KEGG: pnu:Pnuc_0665 amino acid permease-associated region YP_001797952.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: pnu:Pnuc_0664 UBA/ThiF-type NAD/FAD binding protein YP_001797953.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: pnu:Pnuc_0663 pyridoxamine 5'-phosphate oxidase YP_001797955.1 KEGG: pnu:Pnuc_0660 lysine exporter protein (LysE/YggA) YP_001797956.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: pnu:Pnuc_0659 DEAD/DEAH box helicase domain protein YP_001797957.1 KEGG: pnu:Pnuc_0658 chorismate lyase YP_001797958.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pnu:Pnuc_0657 uroporphyrinogen III synthase HEM4 YP_001797959.1 KEGG: pnu:Pnuc_0656 porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase YP_001797960.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001797961.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: pnu:Pnuc_0654 tripartite ATP-independent periplasmic transporter, DctQ component YP_001797962.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: pnu:Pnuc_0653 TRAP dicarboxylate transporter, DctM subunit YP_001797963.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: pnu:Pnuc_0651 lysine decarboxylase YP_001797964.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001797965.1 KEGG: pnu:Pnuc_0648 formate dehydrogenase, subunit FdhD YP_001797966.1 TIGRFAM: methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); KEGG: pnu:Pnuc_0647 methionyl-tRNA synthetase YP_001797967.1 KEGG: pnu:Pnuc_0646 hypothetical protein YP_001797968.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: pnu:Pnuc_0645 chromosome segregation and condensation protein ScpA YP_001797969.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001797971.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: sun:SUN_1248 hypothetical protein YP_001797972.1 KEGG: pnu:Pnuc_0641 methionyl-tRNA formyltransferase YP_001797973.1 KEGG: pnu:Pnuc_0641 methionyl-tRNA formyltransferase YP_001797974.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: pnu:Pnuc_0640 formyl-coenzyme A transferase YP_001797975.1 KEGG: pnu:Pnuc_0638 formyl-coenzyme A transferase YP_001797976.1 PFAM: protein of unknown function DUF81; KEGG: pnu:Pnuc_0632 protein of unknown function DUF81 YP_001797977.1 KEGG: pnu:Pnuc_0631 malonyl-CoA synthase YP_001797978.1 PFAM: Malonyl-CoA decarboxylase; KEGG: pnu:Pnuc_0627 malonyl-CoA decarboxylase YP_001797979.1 KEGG: pnu:Pnuc_0626 transcriptional regulator, LysR family YP_001797980.1 PFAM: regulatory protein LysR; KEGG: pnu:Pnuc_0626 transcriptional regulator, LysR family YP_001797981.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001797982.1 PFAM: DNA polymerase III chi subunit HolC; KEGG: pnu:Pnuc_0624 DNA polymerase III chi subunit, HolC YP_001797983.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: pnu:Pnuc_0623 leucyl aminopeptidase YP_001797984.1 PFAM: permease YjgP/YjgQ family protein; KEGG: pnu:Pnuc_0622 permease YjgP/YjgQ family protein YP_001797985.1 PFAM: permease YjgP/YjgQ family protein; KEGG: pnu:Pnuc_0621 permease YjgP/YjgQ family protein YP_001797986.1 PFAM: regulatory protein LysR; KEGG: pnu:Pnuc_0620 transcriptional regulator CysB-like protein YP_001797987.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001797988.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001797989.1 KEGG: pnu:Pnuc_0615 nicotinate (nicotinamide) nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain protein; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_001797990.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: pnu:Pnuc_0614 iojap-like protein YP_001797991.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001797992.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: pnu:Pnuc_0612 maf protein YP_001797993.1 KEGG: pnu:Pnuc_0610 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter transmembrane region; ABC transporter; SMART: AAA ATPase YP_001797994.1 PFAM: glycosyl transferase family 2; KEGG: pnu:Pnuc_0609 glycosyl transferase, family 2 YP_001797995.1 PFAM: glycosyl transferase family 2; KEGG: pnu:Pnuc_0608 glycosyl transferase, family 2 YP_001797996.1 PFAM: glycosyl transferase family 9; KEGG: pnu:Pnuc_0607 glycosyl transferase, family 9 YP_001797997.1 KEGG: pnu:Pnuc_0606 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein YP_001797998.1 PFAM: glutamyl-tRNA synthetase class Ic; KEGG: pnu:Pnuc_0605 glutamate--tRNA ligase YP_001797999.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: pnu:Pnuc_0604 DEAD/DEAH box helicase domain protein YP_001798000.1 PFAM: protein of unknown function DUF336; KEGG: pnu:Pnuc_0603 protein of unknown function DUF336 YP_001798001.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: pnu:Pnuc_0601 transcriptional regulator, GntR family YP_001798002.1 KEGG: pnu:Pnuc_0599 hypothetical protein YP_001798003.1 KEGG: pnu:Pnuc_0598 AzlC family protein YP_001798004.1 PFAM: AzlC family protein; KEGG: pnu:Pnuc_0598 AzlC family protein YP_001798005.1 PFAM: protein of unknown function UPF0079; KEGG: pnu:Pnuc_0596 protein of unknown function UPF0079 YP_001798006.1 PFAM: cell wall hydrolase/autolysin; KEGG: pnu:Pnuc_0595 N-acetylmuramoyl-L-alanine amidase YP_001798008.1 KEGG: pnu:Pnuc_1608 deoxyribodipyrimidine photolyase-related protein YP_001798009.1 KEGG: pnu:Pnuc_1609 hypothetical protein YP_001798010.1 KEGG: pnu:Pnuc_1610 hypothetical protein YP_001798012.1 PFAM: sodium:dicarboxylate symporter; KEGG: pnu:Pnuc_1745 sodium:dicarboxylate symporter YP_001798013.1 KEGG: reh:H16_A1371 hypothetical membrane spanning protein YP_001798014.1 PFAM: phospholipase/Carboxylesterase; KEGG: pnu:Pnuc_0531 phospholipase/carboxylesterase YP_001798015.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: pnu:Pnuc_0528 TRAP dicarboxylate transporter-DctP subunit YP_001798016.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: pnu:Pnuc_0527 peptidase U62, modulator of DNA gyrase YP_001798017.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001798018.1 PFAM: peptidase M48 Ste24p; KEGG: pnu:Pnuc_0524 STE24 endopeptidase YP_001798019.1 TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; KEGG: pnu:Pnuc_0523 ribosome small subunit-dependent GTPase A YP_001798020.1 PFAM: cobalamin biosynthesis protein CbiB; KEGG: pnu:Pnuc_0522 cobalamin biosynthesis protein CbiB YP_001798021.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001798022.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001798023.1 TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; KEGG: pnu:Pnuc_0518 16S rRNA processing protein RimM YP_001798024.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001798025.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: pnu:Pnuc_0516 protein of unknown function DUF306, MetA and HslJ YP_001798026.1 KEGG: pnu:Pnuc_0515 putative transmembrane protein YP_001798027.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pnu:Pnuc_0514 acyl-CoA dehydrogenase domain protein YP_001798028.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: pnu:Pnuc_0513 electron transfer flavoprotein, alpha subunit YP_001798029.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: pnu:Pnuc_0512 electron transfer flavoprotein beta-subunit YP_001798030.1 PFAM: AMP-dependent synthetase and ligase; KEGG: pnu:Pnuc_0511 AMP-dependent synthetase and ligase YP_001798031.1 TIGRFAM: lytic murein transglycosylase B; KEGG: pnu:Pnuc_0509 lytic murein transglycosylase B YP_001798032.1 PFAM: helix-hairpin-helix motif; KEGG: pnu:Pnuc_0507 helix-hairpin-helix motif YP_001798033.1 KEGG: pnu:Pnuc_0506 hypothetical protein YP_001798036.1 KEGG: rpa:RPA3214 hypothetical protein YP_001798037.1 TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: pnu:Pnuc_0505 ADP-L-glycero-D-manno-heptose-6-epimerase YP_001798038.1 TIGRFAM: rfaE bifunctional protein; PFAM: PfkB domain protein; KEGG: pnu:Pnuc_0504 RfaE bifunctional protein YP_001798039.1 KEGG: pnu:Pnuc_0503 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase YP_001798040.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pnu:Pnuc_0502 hypothetical protein YP_001798041.1 PFAM: histone family protein DNA-binding protein; KEGG: pnu:Pnuc_0501 integration host factor, beta subunit YP_001798042.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001798043.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001798044.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001798045.1 PFAM: Prephenate dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pnu:Pnuc_0497 prephenate dehydrogenase YP_001798046.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001798047.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: pnu:Pnuc_0495 chorismate mutase YP_001798048.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001798049.1 negatively supercoils closed circular double-stranded DNA YP_001798050.1 PFAM: OmpA/MotB domain protein; KEGG: pnu:Pnuc_0492 OmpA/MotB domain protein YP_001798051.1 KEGG: pnu:Pnuc_0491 ubiquinone biosynthesis O-methyltransferase; TIGRFAM: ubiquinone biosynthesis O-methyltransferase; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001798052.1 KEGG: pnu:Pnuc_0490 phosphoglycolate phosphatase YP_001798053.1 KEGG: pnu:Pnuc_0489 TPR repeat-containing protein YP_001798054.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pnu:Pnuc_0489 TPR repeat-containing protein YP_001798055.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: pnu:Pnuc_0489 TPR repeat-containing protein YP_001798056.1 KEGG: pnu:Pnuc_0488 methyltransferase small YP_001798057.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_0485 uncharacterized protein UPF0065 YP_001798058.1 PFAM: Rhodanese domain protein; KEGG: pnu:Pnuc_0484 rhodanese domain protein YP_001798059.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_0483 uncharacterized protein UPF0065 YP_001798060.1 KEGG: pnu:Pnuc_0482 MmgE/PrpD family protein YP_001798061.1 KEGG: pnu:Pnuc_0481 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001798062.1 KEGG: pnu:Pnuc_0479 chromate transporter YP_001798063.1 KEGG: pnu:Pnuc_0479 chromate transporter YP_001798064.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_0478 uncharacterized protein UPF0065 YP_001798065.1 KEGG: pnu:Pnuc_0477 CrcB protein YP_001798066.1 PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: pnu:Pnuc_0476 extradiol ring-cleavage dioxygenase, class III enzyme, subunit B YP_001798069.1 PFAM: peptidase M50; KEGG: pnu:Pnuc_0475 peptidase M50 YP_001798070.1 PFAM: cytochrome c prime; KEGG: pnu:Pnuc_0474 cytochrome c, class II YP_001798071.1 PFAM: cytochrome B561; KEGG: pnu:Pnuc_0473 cytochrome b561 YP_001798072.1 PFAM: protein of unknown function DUF894 DitE; major facilitator superfamily MFS_1; KEGG: pnu:Pnuc_0472 major facilitator superfamily MFS_1 YP_001798073.1 KEGG: pnu:Pnuc_0469 dihydrodipicolinate synthetase YP_001798074.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: pnu:Pnuc_0468 TRAP transporter solute receptor, TAXI family YP_001798075.1 KEGG: pnu:Pnuc_0467 TRAP transporter, 4TM/12TM fusion protein YP_001798076.1 PFAM: peptidase M23; KEGG: pnu:Pnuc_0464 peptidase M23B YP_001798077.1 PFAM: UspA domain protein; KEGG: pnu:Pnuc_0463 UspA domain protein YP_001798078.1 KEGG: pnu:Pnuc_0462 hypothetical protein YP_001798079.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: mms:mma_1109 sulfate permease, SulP family YP_001798080.1 KEGG: pnu:Pnuc_0461 putative transmembrane protein YP_001798081.1 PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: pnu:Pnuc_0460 putative transcriptional regulator, Crp/Fnr family YP_001798082.1 KEGG: pnu:Pnuc_0459 putative transmembrane protein YP_001798083.1 KEGG: pnu:Pnuc_0458 hypothetical protein YP_001798084.1 TIGRFAM: cytochrome c oxidase accessory protein CcoG; KEGG: pnu:Pnuc_0457 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001798085.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c class I; KEGG: pnu:Pnuc_0456 cytochrome c oxidase, cbb3-type, subunit III YP_001798086.1 KEGG: pnu:Pnuc_0455 hypothetical protein YP_001798087.1 CcoO; FixO YP_001798088.1 CcoN; FixN YP_001798089.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: pnu:Pnuc_0452 cytochrome oxidase maturation protein, cbb3-type YP_001798090.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: pnu:Pnuc_0451 heavy metal translocating P-type ATPase YP_001798091.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_0449 uncharacterized protein UPF0065 YP_001798092.1 KEGG: aav:Aave_3391 hypothetical protein YP_001798093.1 KEGG: pnu:Pnuc_0448 hypothetical protein YP_001798094.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: pnu:Pnuc_1509 TRAP transporter solute receptor, TAXI family YP_001798095.1 TIGRFAM: cytochrome c-type biogenesis protein CcmI; PFAM: Tetratricopeptide TPR_3; KEGG: pnu:Pnuc_1510 TPR repeat YP_001798096.1 PFAM: cytochrome C biogenesis protein; KEGG: pnu:Pnuc_1511 cytochrome c biogenesis protein YP_001798097.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pnu:Pnuc_1512 periplasmic protein thiol--disulphide oxidoreductase DsbE YP_001798098.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: pnu:Pnuc_1513 cytochrome c-type biogenesis protein CcmF YP_001798099.1 PFAM: CcmE/CycJ protein; KEGG: pnu:Pnuc_1514 CcmE/CycJ protein YP_001798100.1 TIGRFAM: heme exporter protein CcmD; PFAM: Heme exporter protein D (CcmD); KEGG: pnu:Pnuc_1515 heme exporter protein D (CcmD) YP_001798101.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: pnu:Pnuc_1516 heme exporter protein CcmC YP_001798102.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: pnu:Pnuc_1517 heme exporter protein CcmB YP_001798103.1 KEGG: pnu:Pnuc_1518 heme exporter protein CcmA; TIGRFAM: heme exporter protein CcmA; PFAM: ABC transporter; SMART: AAA ATPase YP_001798104.1 PFAM: DoxX family protein; KEGG: ajs:Ajs_1986 DoxX family protein YP_001798105.1 PFAM: regulatory protein MarR; KEGG: pnu:Pnuc_1523 transcriptional regulator, MarR family YP_001798106.1 KEGG: pnu:Pnuc_1524 beta-lactamase domain protein YP_001798107.1 KEGG: pnu:Pnuc_1524 beta-lactamase domain protein YP_001798108.1 KEGG: pnu:Pnuc_1525 hypothetical protein YP_001798109.1 KEGG: pnu:Pnuc_1526 alcohol dehydrogenase, zinc-binding domain protein YP_001798110.1 KEGG: pnu:Pnuc_1528 hypothetical protein YP_001798111.1 PFAM: histone deacetylase superfamily; KEGG: pnu:Pnuc_1529 histone deacetylase superfamily YP_001798112.1 KEGG: pnu:Pnuc_1530 hypothetical protein YP_001798113.1 KEGG: pnu:Pnuc_1531 putative lipoprotein YP_001798115.1 PFAM: protein of unknown function DUF1345; KEGG: yen:YE0004 hypothetical protein YP_001798116.1 KEGG: pnu:Pnuc_1532 hypothetical protein YP_001798117.1 KEGG: pnu:Pnuc_1533 hypothetical protein YP_001798118.1 TIGRFAM: peroxiredoxin; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pnu:Pnuc_1534 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001798119.1 TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pnu:Pnuc_1535 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001798120.1 KEGG: pnu:Pnuc_1563 hypothetical protein YP_001798121.1 KEGG: pnu:Pnuc_1563 hypothetical protein YP_001798123.1 KEGG: pnu:Pnuc_0874 hypothetical protein YP_001798125.1 PFAM: nitroreductase; KEGG: rfr:Rfer_2142 nitroreductase YP_001798129.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 non-essential domain protein; sigma-70 region 1.2; KEGG: pnu:Pnuc_1698 RNA polymerase, sigma 70 subunit, RpoD YP_001798130.1 KEGG: pnu:Pnuc_1699 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger CHC2-family protein; TOPRIM domain protein; DNA primase catalytic core domain; SMART: Toprim sub domain protein YP_001798131.1 KEGG: pnu:Pnuc_1700 GatB/YqeY domain protein YP_001798132.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001798133.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001798134.1 PFAM: protein of unknown function DUF198; KEGG: pnu:Pnuc_1703 protein of unknown function DUF198 YP_001798135.1 TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: transketolase central region; transketolase domain protein; KEGG: pnu:Pnuc_1704 deoxyxylulose-5-phosphate synthase YP_001798136.1 PFAM: Polyprenyl synthetase; KEGG: pnu:Pnuc_1705 polyprenyl synthetase YP_001798137.1 PFAM: Exonuclease VII small subunit; KEGG: pnu:Pnuc_1706 exonuclease VII, small subunit YP_001798138.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: pnu:Pnuc_1707 Rieske (2Fe-2S) domain protein YP_001798139.1 PFAM: Rhodanese domain protein; KEGG: pnu:Pnuc_1708 3-mercaptopyruvate sulfurtransferase YP_001798140.1 PFAM: zinc/iron permease; KEGG: pnu:Pnuc_1709 zinc/iron permease YP_001798141.1 KEGG: pnu:Pnuc_1711 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein class 2 YP_001798142.1 KEGG: pnu:Pnuc_1712 putative transmembrane protein YP_001798143.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_001798144.1 KEGG: pnu:Pnuc_1714 putative transmembrane protein YP_001798145.1 PFAM: UvrD/REP helicase; KEGG: pnu:Pnuc_1715 UvrD/REP helicase YP_001798146.1 TIGRFAM: valyl-tRNA synthetase; KEGG: pnu:Pnuc_1716 valyl-tRNA synthetase YP_001798147.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: pnu:Pnuc_1717 UTP-glucose-1-phosphate uridylyltransferase GalU YP_001798148.1 PFAM: SirA family protein; KEGG: pnu:Pnuc_1718 SirA family protein YP_001798149.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001798150.1 PFAM: protein of unknown function DUF1468; KEGG: pnu:Pnuc_1720 protein of unknown function DUF1468 YP_001798151.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: pnu:Pnuc_1721 protein of unknown function DUF112, transmembrane YP_001798152.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001798153.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: pnu:Pnuc_1723 NAD-dependent epimerase/dehydratase YP_001798154.1 catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose YP_001798155.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001798156.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_1726 ABC transporter YP_001798157.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_1727 ABC transporter YP_001798158.1 KEGG: pnu:Pnuc_1731 hydroxymethylbutenyl pyrophosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein YP_001798159.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: pnu:Pnuc_1732 peptidylprolyl isomerase, FKBP-type YP_001798160.1 PFAM: DNA repair protein RadC; KEGG: pnu:Pnuc_1733 DNA repair protein RadC YP_001798161.1 required for 70S ribosome assembly YP_001798162.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001798163.1 PFAM: fatty acid desaturase; KEGG: pnu:Pnuc_1736 fatty acid desaturase YP_001798164.1 PFAM: Fmu (Sun) domain protein; KEGG: pnu:Pnuc_1737 Fmu (Sun) domain protein YP_001798165.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; KEGG: pnu:Pnuc_1738 phosphoribosylglycinamide formyltransferase YP_001798166.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001798167.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001798168.1 KEGG: pnu:Pnuc_1742 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001798169.1 catalyzes the formation of dUMP from dUTP YP_001798170.1 KEGG: pnu:Pnuc_1747 hypothetical protein YP_001798171.1 KEGG: pnu:Pnuc_1748 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001798172.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: pnu:Pnuc_1749 ATP-dependent Clp protease adaptor protein ClpS YP_001798173.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: pnu:Pnuc_1750 putative cold-shock DNA-binding domain protein YP_001798174.1 PFAM: protein of unknown function DUF192; KEGG: pnu:Pnuc_1751 protein of unknown function DUF192 YP_001798175.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001798176.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001798177.1 KEGG: pnu:Pnuc_1755 hypothetical protein YP_001798178.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001798179.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: pnu:Pnuc_1757 integral membrane protein MviN YP_001798180.1 KEGG: pnu:Pnuc_1758 hypothetical protein YP_001798181.1 PFAM: SNARE associated Golgi protein; KEGG: pnu:Pnuc_1759 DedA YP_001798182.1 KEGG: pnu:Pnuc_1760 tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; SMART: AAA ATPase YP_001798183.1 KEGG: pnu:Pnuc_1761 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001798184.1 PFAM: protein of unknown function UPF0118; KEGG: pnu:Pnuc_1762 protein of unknown function UPF0118 YP_001798185.1 PFAM: Chromosomal replication initiator DnaA; KEGG: pnu:Pnuc_1763 chromosomal replication initiator, DnaA YP_001798186.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; KEGG: pnu:Pnuc_1764 HAD-superfamily subfamily IB hydrolase, TIGR01490 YP_001798187.1 KEGG: pnu:Pnuc_1765 poly(A) polymerase; TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region YP_001798188.1 KEGG: pnu:Pnuc_1767 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase YP_001798189.1 TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: pnu:Pnuc_1768 chaperone protein DnaJ YP_001798190.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001798191.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001798192.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001798193.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001798194.1 PFAM: ATP-NAD/AcoX kinase; KEGG: pnu:Pnuc_1773 NAD(+) kinase YP_001798195.1 KEGG: pnu:Pnuc_1774 DNA repair protein RecN YP_001798196.1 KEGG: pnu:Pnuc_1774 DNA repair protein RecN YP_001798197.1 PFAM: glutamate-ammonia ligase adenylyltransferase; KEGG: pnu:Pnuc_1775 (glutamate--ammonia-ligase) adenylyltransferase YP_001798199.1 KEGG: pnu:Pnuc_1776 membrane protein-like protein YP_001798200.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: pnu:Pnuc_1778 peptidase U62, modulator of DNA gyrase YP_001798201.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001798202.1 TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: pnu:Pnuc_1780 ATP--cobalamin adenosyltransferase YP_001798203.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: pnu:Pnuc_1783 glycolate oxidase iron-sulfur subunit YP_001798204.1 KEGG: pnu:Pnuc_1785 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent YP_001798205.1 TIGRFAM: 4-hydroxybenzoate polyprenyl transferase; PFAM: UbiA prenyltransferase; KEGG: pnu:Pnuc_1786 4-hydroxybenzoate polyprenyl transferase YP_001798206.1 catalyzes branch migration in Holliday junction intermediates YP_001798207.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001798208.1 KEGG: pnu:Pnuc_1789 queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylase, various specificities; queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase YP_001798209.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: pnu:Pnuc_1790 preprotein translocase, YajC subunit YP_001798210.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecD; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: pnu:Pnuc_1791 protein-export membrane protein SecD YP_001798211.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001798212.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: pnu:Pnuc_1793 three-deoxy-D-manno-octulosonic-acid transferase domain protein YP_001798213.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001798214.1 PFAM: glutathione S-transferase domain; KEGG: pnu:Pnuc_1795 glutathione S-transferase, N-terminal domain YP_001798215.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001798216.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: pnu:Pnuc_1797 alanine dehydrogenase/PNT domain protein YP_001798217.1 KEGG: pnu:Pnuc_1798 putative transmembrane NAD(P) transhydrogenase transmembrane protein YP_001798218.1 PFAM: NAD(P) transhydrogenase beta subunit; KEGG: pnu:Pnuc_1799 NAD(P) transhydrogenase, beta subunit YP_001798219.1 KEGG: pnu:Pnuc_1804 hypothetical protein YP_001798220.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001798221.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001798222.1 KEGG: pnu:Pnuc_1807 putative diguanylate phosphodiesterase YP_001798223.1 KEGG: pnu:Pnuc_1807 putative diguanylate phosphodiesterase YP_001798224.1 KEGG: pnu:Pnuc_1809 histidine kinase YP_001798225.1 KEGG: pnu:Pnuc_1810 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase YP_001798226.1 KEGG: pnu:Pnuc_1812 phosphoribosylaminoimidazole carboxylase, ATPase subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase subunit; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp YP_001798227.1 KEGG: pnu:Pnuc_1813 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001798228.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001798229.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001798230.1 KEGG: pnu:Pnuc_1816 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta YP_001798231.1 PFAM: phosphoglycerate kinase; KEGG: pnu:Pnuc_1817 phosphoglycerate kinase YP_001798232.1 TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; KEGG: pnu:Pnuc_1818 branched-chain amino acid aminotransferase YP_001798233.1 KEGG: pnu:Pnuc_1819 hypothetical protein YP_001798234.1 TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; KEGG: pnu:Pnuc_1820 lipopolysaccharide heptosyltransferase II YP_001798235.1 KEGG: pnu:Pnuc_1821 hypothetical protein YP_001798236.1 PFAM: peptidase M48 Ste24p; KEGG: pnu:Pnuc_1823 peptidase M48, Ste24p YP_001798237.1 KEGG: pnu:Pnuc_1248 hypothetical protein YP_001798238.1 KEGG: pnu:Pnuc_0562 hypothetical protein YP_001798239.1 KEGG: hch:HCH_00360 predicted hydrolase or acyltransferase (alpha/beta hydrolase superfamily) YP_001798241.1 PFAM: Integral membrane protein TerC; KEGG: pnu:Pnuc_1829 integral membrane protein TerC YP_001798242.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001798243.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001798244.1 PFAM: regulatory protein RecX; KEGG: pnu:Pnuc_1832 regulatory protein RecX YP_001798245.1 KEGG: pnu:Pnuc_1833 RecA protein; TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: AAA ATPase YP_001798246.1 KEGG: pnu:Pnuc_1834 hypothetical protein YP_001798247.1 KEGG: pnu:Pnuc_1846 hypothetical protein YP_001798248.1 PFAM: protein of unknown function UPF0126; KEGG: pnu:Pnuc_1850 protein of unknown function UPF0126 YP_001798249.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: pnu:Pnuc_1852 transferase hexapeptide repeat YP_001798250.1 KEGG: pol:Bpro_4891 Rh-like protein/ammonium transporter YP_001798251.1 KEGG: pnu:Pnuc_1855 hypothetical protein YP_001798252.1 KEGG: pnu:Pnuc_1856 OsmC family protein YP_001798253.1 PFAM: Rhodanese domain protein; KEGG: pnu:Pnuc_1857 rhodanese domain protein YP_001798254.1 PFAM: protein of unknown function DUF1504; KEGG: pnu:Pnuc_1858 protein of unknown function DUF1504 YP_001798255.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001798256.1 PFAM: protein of unknown function UPF0054; KEGG: pnu:Pnuc_1860 protein of unknown function UPF0054 YP_001798257.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: pnu:Pnuc_1861 CBS domain containing protein YP_001798258.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pnu:Pnuc_1862 apolipoprotein N-acyltransferase YP_001798259.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001798260.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001798261.1 TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Polynucleotide kinase 3 phosphatase central region; KEGG: pnu:Pnuc_1865 histidinol-phosphate phosphatase family protein YP_001798262.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: pnu:Pnuc_1866 phospholipid/glycerol acyltransferase YP_001798263.1 TIGRFAM: dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; KEGG: pnu:Pnuc_1867 dimethyladenosine transferase YP_001798264.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: pnu:Pnuc_1869 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001798265.1 PFAM: OstA family protein; Organic solvent tolerance protein; KEGG: pnu:Pnuc_1870 organic solvent tolerance protein YP_001798266.1 PFAM: aminoglycoside phosphotransferase; KEGG: pnu:Pnuc_1871 aminoglycoside phosphotransferase YP_001798267.1 PFAM: Nucleotidyl transferase; KEGG: pnu:Pnuc_1872 nucleotidyl transferase YP_001798268.1 PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: pnu:Pnuc_1873 peptidase M24 YP_001798269.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: pnu:Pnuc_1874 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001798270.1 TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; dihydroorotate dehydrogenase; KEGG: pnu:Pnuc_1875 putative TIM-barrel protein, nifR3 family YP_001798271.1 PFAM: helix-turn-helix Fis-type; KEGG: pnu:Pnuc_1876 transcriptional regulator, fis family YP_001798272.1 involved in de novo purine biosynthesis YP_001798273.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001798274.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001798275.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001798276.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001798277.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001798278.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: pnu:Pnuc_1883 iron-sulfur cluster assembly accessory protein YP_001798279.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001798280.1 PFAM: ribosomal protein S9; KEGG: pnu:Pnuc_1885 ribosomal protein S9 YP_001798281.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001798282.1 PFAM: OsmC family protein; KEGG: pnu:Pnuc_1887 OsmC family protein YP_001798283.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001798284.1 PFAM: ABC transporter transmembrane region; ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_1890 ABC transporter YP_001798285.1 PFAM: NUDIX hydrolase; KEGG: pnu:Pnuc_1891 NUDIX hydrolase YP_001798286.1 TIGRFAM: aspartyl-tRNA synthetase; PFAM: GAD domain protein; tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: pnu:Pnuc_1892 aspartyl-tRNA synthetase YP_001798287.1 PFAM: protein of unknown function DUF502; KEGG: pnu:Pnuc_1893 protein of unknown function DUF502 YP_001798288.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: pnu:Pnuc_1894 2-polyprenylphenol 6-hydroxylase YP_001798289.1 KEGG: pnu:Pnuc_1895 protein of unknown function DUF1243 YP_001798290.1 PFAM: import inner membrane translocase subunit Tim44; KEGG: pnu:Pnuc_1896 import inner membrane translocase, subunit Tim44 YP_001798291.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: pnu:Pnuc_1897 ubiquinone/menaquinone biosynthesis methyltransferase YP_001798292.1 PFAM: protein of unknown function DUF971; KEGG: pnu:Pnuc_1898 protein of unknown function DUF971 YP_001798293.1 PFAM: FAD linked oxidase domain protein; KEGG: pnu:Pnuc_1899 FAD linked oxidase domain protein YP_001798294.1 TIGRFAM: threonine dehydratase, biosynthetic; PFAM: Threonine dehydratase domain protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pnu:Pnuc_1900 threonine dehydratase, biosynthetic YP_001798295.1 PFAM: 5-nucleotidase; KEGG: pnu:Pnuc_1901 5-nucleotidase YP_001798296.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: pnu:Pnuc_1903 single-strand binding protein YP_001798297.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: pnu:Pnuc_1904 major facilitator superfamily MFS_1 YP_001798298.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter; KEGG: pnu:Pnuc_1905 excinuclease ABC, A subunit YP_001798299.1 PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: pnu:Pnuc_1906 potassium efflux system protein YP_001798300.1 KEGG: pnu:Pnuc_1907 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001798301.1 TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: pnu:Pnuc_1908 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family YP_001798302.1 PFAM: protein of unknown function DUF1239; KEGG: pnu:Pnuc_1909 protein of unknown function DUF1239 YP_001798303.1 PFAM: OstA family protein; KEGG: pnu:Pnuc_1910 OstA family protein YP_001798304.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pnu:Pnuc_1911 ABC transporter YP_001798305.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: pnu:Pnuc_1912 sigma 54 modulation protein/ribosomal protein S30EA YP_001798306.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: pnu:Pnuc_1913 putative PTS IIA-like nitrogen-regulatory protein PtsN YP_001798307.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_001798308.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_1915 hypothetical protein YP_001798309.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; KEGG: pnu:Pnuc_1916 A/G-specific adenine glycosylase YP_001798310.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001798311.1 PFAM: outer membrane lipoprotein LolB; KEGG: pnu:Pnuc_1918 outer membrane lipoprotein LolB YP_001798312.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001798313.1 KEGG: pnu:Pnuc_1920 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_001798314.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001798315.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001798316.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pnu:Pnuc_1923 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001798317.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001798318.1 TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: pnu:Pnuc_1925 putative methyltransferase YP_001798319.1 PFAM: peptidase M16 domain protein; KEGG: pnu:Pnuc_1926 peptidase M16 domain protein YP_001798320.1 PFAM: peptidase M16 domain protein; KEGG: pnu:Pnuc_1927 peptidase M16 domain protein YP_001798321.1 KEGG: pnu:Pnuc_1928 signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_001798322.1 TIGRFAM: RNA polymerase sigma factor RpoH; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; KEGG: pnu:Pnuc_1929 RNA polymerase, sigma 32 subunit, RpoH YP_001798323.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; electron transport protein SCO1/SenC; KEGG: pnu:Pnuc_1930 electron transport protein SCO1/SenC YP_001798324.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001798325.1 PFAM: cytochrome oxidase assembly; KEGG: pnu:Pnuc_1932 cytochrome oxidase assembly YP_001798326.1 KEGG: pnu:Pnuc_1933 putative transmembrane protein YP_001798327.1 KEGG: pnu:Pnuc_1934 SURF1 family protein YP_001798328.1 KEGG: pnu:Pnuc_1935 hypothetical protein YP_001798329.1 PFAM: cytochrome c oxidase subunit III; KEGG: pnu:Pnuc_1936 cytochrome c oxidase, subunit III YP_001798330.1 KEGG: pnu:Pnuc_1937 putative transmembrane protein YP_001798331.1 PFAM: cytochrome c oxidase assembly protein CtaG/Cox11; KEGG: pnu:Pnuc_1938 cytochrome c oxidase assembly protein CtaG/Cox11 YP_001798332.1 KEGG: pnu:Pnuc_1939 cytochrome-c oxidase; TIGRFAM: cytochrome c oxidase, subunit I; PFAM: cytochrome c oxidase subunit I YP_001798333.1 TIGRFAM: cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; cytochrome C oxidase subunit II transmembrane region; KEGG: pnu:Pnuc_1940 cytochrome c oxidase, subunit II YP_001798334.1 PFAM: Methyltransferase type 11; KEGG: pnu:Pnuc_1941 methyltransferase type 11 YP_001798335.1 KEGG: pnu:Pnuc_1942 phosphoribosyltransferase YP_001798336.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: pnu:Pnuc_1943 RNA methyltransferase, TrmH family, group 2 YP_001798337.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001798338.1 TIGRFAM: protein-export protein SecB; PFAM: protein export chaperone SecB; KEGG: pnu:Pnuc_1945 protein-export protein SecB YP_001798339.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; KEGG: pnu:Pnuc_1946 glutaredoxin 3 YP_001798340.1 PFAM: Rhodanese domain protein; KEGG: pnu:Pnuc_1947 rhodanese domain protein YP_001798341.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001798342.1 KEGG: pnu:Pnuc_1949 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001798343.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: pnu:Pnuc_1951 phosphoenolpyruvate-protein phosphotransferase YP_001798344.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: pnu:Pnuc_1952 phosphotransferase system, phosphocarrier protein HPr YP_001798345.1 PFAM: PTS system fructose subfamily IIA component; KEGG: pnu:Pnuc_1953 PTS system fructose subfamily IIA component YP_001798346.1 TIGRFAM: glutamate--cysteine ligase; PFAM: glutamate--cysteine ligase GshA; KEGG: pnu:Pnuc_1955 glutamate--cysteine ligase YP_001798347.1 KEGG: pnu:Pnuc_1956 ammonium transporter YP_001798348.1 PFAM: nitrogen regulatory protein P-II; KEGG: pnu:Pnuc_1957 nitrogen regulatory protein P-II YP_001798349.1 PFAM: conserved hypothetical protein; KEGG: pnu:Pnuc_1958 putative signal peptide protein YP_001798350.1 PFAM: protein of unknown function DUF526; KEGG: pnu:Pnuc_1959 protein of unknown function DUF526 YP_001798351.1 KEGG: pnu:Pnuc_1960 hypothetical protein YP_001798352.1 KEGG: pnu:Pnuc_1960 hypothetical protein YP_001798353.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001798354.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism YP_001798355.1 PFAM: protein of unknown function DUF493; KEGG: pnu:Pnuc_1963 protein of unknown function DUF493 YP_001798356.1 KEGG: pnu:Pnuc_1964 hydrolase of the alpha/beta superfamily YP_001798357.1 KEGG: pnu:Pnuc_1965 putative ferredoxin 2fe-2s protein YP_001798358.1 KEGG: pnu:Pnuc_1966 VanZ family protein YP_001798359.1 TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: pnu:Pnuc_1967 biotin--acetyl-CoA-carboxylase ligase YP_001798360.1 TIGRFAM: transcriptional activator, Baf family; PFAM: Bvg accessory factor; KEGG: pnu:Pnuc_1968 putative transcriptional acitvator, Baf family YP_001798361.1 TIGRFAM: cytidyltransferase-related domain protein; rfaE bifunctional protein; PFAM: cytidylyltransferase; KEGG: pnu:Pnuc_1969 RfaE bifunctional protein YP_001798362.1 PFAM: glutathione peroxidase; KEGG: pnu:Pnuc_1970 glutathione peroxidase YP_001798363.1 KEGG: pnu:Pnuc_1972 protein of unknown function DUF1365 YP_001798364.1 KEGG: pnu:Pnuc_1972 protein of unknown function DUF1365 YP_001798365.1 PFAM: DSBA oxidoreductase; KEGG: pnu:Pnuc_1975 DsbA oxidoreductase YP_001798366.1 PFAM: Sporulation domain protein; KEGG: pnu:Pnuc_1976 sporulation domain protein YP_001798367.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001798368.1 PFAM: Domain of unknown function DUF1840; KEGG: pnu:Pnuc_1978 hypothetical protein YP_001798369.1 KEGG: pnu:Pnuc_1979 methionine synthase; TIGRFAM: methionine synthase; PFAM: dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; Vitamin B12 dependent methionine synthase activation region; cobalamin B12-binding domain protein YP_001798370.1 PFAM: homocysteine S-methyltransferase; KEGG: pnu:Pnuc_1980 methionine synthase YP_001798371.1 KEGG: reh:H16_A0141 hypothetical membrane associated protein YP_001798372.1 KEGG: pnu:Pnuc_1982 beta-lactamase domain protein YP_001798373.1 KEGG: pnu:Pnuc_1985 hypothetical protein YP_001798374.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: pnu:Pnuc_1986 flavin reductase domain protein, FMN-binding YP_001798375.1 KEGG: pnu:Pnuc_1990 RND efflux system, outer membrane lipoprotein, NodT family YP_001798379.1 TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: glutamine amidotransferase class-II; sugar isomerase (SIS); KEGG: pnu:Pnuc_1991 glucosamine--fructose-6-phosphate aminotransferase, isomerizing YP_001798380.1 TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: pnu:Pnuc_1992 UDP-N-acetylglucosamine pyrophosphorylase YP_001798381.1 PFAM: PP-loop domain protein; KEGG: pnu:Pnuc_1993 PP-loop domain protein YP_001798382.1 KEGG: pnu:Pnuc_1994 dihydroneopterin aldolase YP_001798383.1 related to short-chain alcohol dehydrogenase; KEGG: pnu:Pnuc_1995 short-chain dehydrogenase/reductase SDR YP_001798384.1 PFAM: protein of unknown function DUF185; KEGG: pnu:Pnuc_1996 protein of unknown function DUF185 YP_001798385.1 PFAM: Polynucleotide adenylyltransferase region; KEGG: pnu:Pnuc_1997 polynucleotide adenylyltransferase region YP_001798386.1 KEGG: pnu:Pnuc_1998 NAD-dependent epimerase/dehydratase YP_001798387.1 KEGG: pnu:Pnuc_1998 NAD-dependent epimerase/dehydratase YP_001798388.1 PFAM: Lytic transglycosylase catalytic; KEGG: pnu:Pnuc_1999 lytic transglycosylase, catalytic YP_001798389.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: pnu:Pnuc_2000 5-formyltetrahydrofolate cyclo-ligase YP_001798390.1 KEGG: pnu:Pnuc_2001 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_001798391.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001798392.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001798393.1 KEGG: pnu:Pnuc_2004 lipid A biosynthesis acyltransferase YP_001798394.1 KEGG: pnu:Pnuc_2004 lipid A biosynthesis acyltransferase YP_001798395.1 PFAM: lipid A biosynthesis acyltransferase; KEGG: pnu:Pnuc_2005 lipid A biosynthesis acyltransferase YP_001798396.1 PFAM: diaminopimelate epimerase; KEGG: pnu:Pnuc_2006 diaminopimelate epimerase YP_001798397.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001798398.1 KEGG: pnu:Pnuc_2008 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase YP_001798399.1 KEGG: pnu:Pnuc_2009 major facilitator superfamily MFS_1 YP_001798400.1 TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12; KEGG: pnu:Pnuc_2010 methionine biosynthesis protein MetW YP_001798401.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_001798402.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001798403.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001798404.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: pnu:Pnuc_2014 transcriptional regulator, TraR/DksA family YP_001798405.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: pnu:Pnuc_2015 cobalamin synthesis protein, P47K YP_001798406.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: pnu:Pnuc_2016 phage integrase family protein YP_001798407.1 PFAM: protein of unknown function DUF484; KEGG: pnu:Pnuc_2017 protein of unknown function DUF484 YP_001798408.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001798409.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001798410.1 TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; KEGG: pnu:Pnuc_2020 glutamyl-tRNA(Gln) amidotransferase, C subunit YP_001798411.1 functions in MreBCD complex in some organisms YP_001798412.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001798413.1 KEGG: pnu:Pnuc_2023 rod shape-determining protein MreD YP_001798414.1 KEGG: pnu:Pnuc_2024 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain YP_001798415.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: pnu:Pnuc_2025 rod shape-determining protein RodA YP_001798416.1 PFAM: histone family protein DNA-binding protein; KEGG: pnu:Pnuc_2026 histone family protein DNA-binding protein YP_001798417.1 KEGG: pnu:Pnuc_2027 hypothetical protein YP_001798418.1 KEGG: pnu:Pnuc_2028 aspartyl/asparaginyl beta-hydroxylase YP_001798419.1 PFAM: carbonic anhydrase; KEGG: pnu:Pnuc_2030 carbonate dehydratase YP_001798420.1 KEGG: pnu:Pnuc_2032 metallophosphoesterase YP_001798421.1 KEGG: pnu:Pnuc_2032 metallophosphoesterase YP_001798422.1 SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: pnu:Pnuc_2033 protein kinase YP_001798423.1 KEGG: pnu:Pnuc_2033 protein kinase YP_001798424.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pnu:Pnuc_2035 pseudouridine synthase YP_001798425.1 TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; KEGG: pnu:Pnuc_2036 peptide chain release factor 3 YP_001798426.1 KEGG: pnu:Pnuc_2037 hypothetical protein YP_001798427.1 KEGG: pnu:Pnuc_0082 MOSC domain containing protein YP_001798428.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pnu:Pnuc_2038 GCN5-related N-acetyltransferase YP_001798429.1 KEGG: mms:mma_1887 hypothetical protein YP_001798430.1 KEGG: bra:BRADO3283 hypothetical protein YP_001798431.1 KEGG: pnu:Pnuc_2042 hypothetical protein YP_001798432.1 PFAM: cytochrome B561; KEGG: bmu:Bmul_5867 cytochrome b561 YP_001798433.1 KEGG: pna:Pnap_1533 diheme cytochrome c YP_001798434.1 PFAM: Domain of unknown function DUF1924; KEGG: bmu:Bmul_5869 domain of unknown function DUF1924 YP_001798435.1 KEGG: pnu:Pnuc_2045 glutathione S-transfersae-related protein YP_001798436.1 KEGG: pnu:Pnuc_2046 haloacid dehalogenase, type II; TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001798437.1 KEGG: bxe:Bxe_B3014 hypothetical protein YP_001798439.1 PFAM: response regulator receiver; helix-turn-helix Fis-type; KEGG: pnu:Pnuc_2074 two component transcriptional regulator, fis family YP_001798440.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pnu:Pnuc_2075 integral membrane sensor signal transduction histidine kinase YP_001798441.1 KEGG: pnu:Pnuc_2076 putative periplasmic ligand-binding sensor protein YP_001798442.1 PFAM: Fmu (Sun) domain protein; KEGG: pnu:Pnuc_2077 sun protein YP_001798443.1 PFAM: peptidase M48 Ste24p; KEGG: reu:Reut_A3406 heat shock protein HtpX YP_001798444.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: pnu:Pnuc_2078 methionyl-tRNA formyltransferase YP_001798445.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001798446.1 PFAM: SMF family protein; KEGG: pnu:Pnuc_2080 DNA protecting protein DprA YP_001798447.1 decatenates replicating daughter chromosomes YP_001798448.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_001798449.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001798450.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: pnu:Pnuc_2085 60 kDa inner membrane insertion protein YP_001798451.1 PFAM: protein of unknown function DUF37; KEGG: pnu:Pnuc_2086 protein of unknown function DUF37 YP_001798452.1 TIGRFAM: ribonuclease P protein component; KEGG: pnu:Pnuc_2087 ribonuclease P protein component YP_001798453.1 in Escherichia coli transcription of this gene is enhanced by polyamines