-- dump date   	20140619_235249
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1030843000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1030843000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1030843000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843000004	Walker A motif; other site
1030843000005	ATP binding site [chemical binding]; other site
1030843000006	Walker B motif; other site
1030843000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1030843000008	DnaA box-binding interface [nucleotide binding]; other site
1030843000009	putative trimer interface [polypeptide binding]; other site
1030843000010	Bacterial transferase hexapeptide (six repeats); Region: Hexapep; pfam00132
1030843000011	putative CoA binding site [chemical binding]; other site
1030843000012	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
1030843000013	putative trimer interface [polypeptide binding]; other site
1030843000014	putative active site [active]
1030843000015	putative substrate binding site [chemical binding]; other site
1030843000016	putative CoA binding site [chemical binding]; other site
1030843000017	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1030843000018	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1030843000019	NAD-dependent deacetylase; Provisional; Region: PRK00481
1030843000020	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1030843000021	NAD+ binding site [chemical binding]; other site
1030843000022	substrate binding site [chemical binding]; other site
1030843000023	Zn binding site [ion binding]; other site
1030843000024	phosphodiesterase YaeI; Provisional; Region: PRK11340
1030843000025	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1030843000026	putative active site [active]
1030843000027	putative metal binding site [ion binding]; other site
1030843000028	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1030843000029	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1030843000030	potential protein location (hypothetical protein PGTDC60_0007 [Porphyromonas gingivalis TDC60]) that overlaps RNA (tRNA-N)
1030843000031	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
1030843000032	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843000033	Walker A motif; other site
1030843000034	ATP binding site [chemical binding]; other site
1030843000035	Walker B motif; other site
1030843000036	arginine finger; other site
1030843000037	UvrB/uvrC motif; Region: UVR; pfam02151
1030843000038	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843000039	Walker A motif; other site
1030843000040	ATP binding site [chemical binding]; other site
1030843000041	Walker B motif; other site
1030843000042	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1030843000043	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1030843000044	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1030843000045	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1030843000046	Beta-lactamase; Region: Beta-lactamase; pfam00144
1030843000047	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
1030843000048	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1030843000049	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843000050	homodimer interface [polypeptide binding]; other site
1030843000051	catalytic residue [active]
1030843000052	2-phosphosulpholactate phosphatase; Region: 2-ph_phosp; pfam04029
1030843000053	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1030843000054	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1030843000055	active site
1030843000056	phosphorylation site [posttranslational modification]
1030843000057	intermolecular recognition site; other site
1030843000058	dimerization interface [polypeptide binding]; other site
1030843000059	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843000060	Walker A motif; other site
1030843000061	ATP binding site [chemical binding]; other site
1030843000062	Walker B motif; other site
1030843000063	arginine finger; other site
1030843000064	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1030843000065	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1030843000066	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843000067	ATP binding site [chemical binding]; other site
1030843000068	Mg2+ binding site [ion binding]; other site
1030843000069	G-X-G motif; other site
1030843000070	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1030843000071	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1030843000072	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1030843000073	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1030843000074	FMN binding site [chemical binding]; other site
1030843000075	active site
1030843000076	catalytic residues [active]
1030843000077	substrate binding site [chemical binding]; other site
1030843000078	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1030843000079	putative transporter; Provisional; Region: PRK11660
1030843000080	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1030843000081	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1030843000082	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1030843000083	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1030843000084	CoA binding domain; Region: CoA_binding; smart00881
1030843000085	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1030843000086	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1030843000087	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
1030843000088	active site
1030843000089	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1030843000090	homotrimer interaction site [polypeptide binding]; other site
1030843000091	zinc binding site [ion binding]; other site
1030843000092	CDP-binding sites; other site
1030843000093	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1030843000094	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1030843000095	active site
1030843000096	catalytic motif [active]
1030843000097	Zn binding site [ion binding]; other site
1030843000098	partial ROK family transcriptional repressor with glucose kinase domain; similar to nr, gi|188994244|ref|YP_001928496.1| partial ROK family transcriptional repressor with glucose kinase domain [Porphyromonas gingivalis ATCC 33277] partial ROK family transcriptional repressor with glucose kinase domain [Porphyromonas gingivalis ATCC 33277], percent identity 93.3 in 30 aa, BLASTP E(): 2e-8
1030843000099	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1030843000100	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
1030843000101	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1030843000102	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1030843000103	RmuC family; Region: RmuC; pfam02646
1030843000104	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1030843000105	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1030843000106	catalytic residues [active]
1030843000107	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1030843000108	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1030843000109	active site
1030843000110	PHP Thumb interface [polypeptide binding]; other site
1030843000111	metal binding site [ion binding]; metal-binding site
1030843000112	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1030843000113	generic binding surface II; other site
1030843000114	generic binding surface I; other site
1030843000115	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1030843000116	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1030843000117	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1030843000118	dimer interface [polypeptide binding]; other site
1030843000119	active site
1030843000120	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1030843000121	folate binding site [chemical binding]; other site
1030843000122	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
1030843000123	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
1030843000124	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
1030843000125	active site
1030843000126	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
1030843000127	PA14 domain; Region: PA14; pfam07691
1030843000128	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843000129	heat shock protein 90; Provisional; Region: PRK05218
1030843000130	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843000131	ATP binding site [chemical binding]; other site
1030843000132	Mg2+ binding site [ion binding]; other site
1030843000133	G-X-G motif; other site
1030843000134	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1030843000135	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1030843000136	FtsH Extracellular; Region: FtsH_ext; pfam06480
1030843000137	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1030843000138	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843000139	Walker A motif; other site
1030843000140	ATP binding site [chemical binding]; other site
1030843000141	Walker B motif; other site
1030843000142	arginine finger; other site
1030843000143	Peptidase family M41; Region: Peptidase_M41; pfam01434
1030843000144	GTP-binding protein YchF; Reviewed; Region: PRK09601
1030843000145	YchF GTPase; Region: YchF; cd01900
1030843000146	G1 box; other site
1030843000147	GTP/Mg2+ binding site [chemical binding]; other site
1030843000148	Switch I region; other site
1030843000149	G2 box; other site
1030843000150	Switch II region; other site
1030843000151	G3 box; other site
1030843000152	G4 box; other site
1030843000153	G5 box; other site
1030843000154	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1030843000155	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1030843000156	Peptidase family M23; Region: Peptidase_M23; pfam01551
1030843000157	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1030843000158	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1030843000159	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843000160	Walker A/P-loop; other site
1030843000161	ATP binding site [chemical binding]; other site
1030843000162	Q-loop/lid; other site
1030843000163	ABC transporter signature motif; other site
1030843000164	Walker B; other site
1030843000165	D-loop; other site
1030843000166	H-loop/switch region; other site
1030843000167	aspartate kinase III; Validated; Region: PRK09084
1030843000168	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
1030843000169	putative catalytic residues [active]
1030843000170	nucleotide binding site [chemical binding]; other site
1030843000171	aspartate binding site [chemical binding]; other site
1030843000172	ACT domains located C-terminal to the catalytic domain of  the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC-like_1; cd04912
1030843000173	dimer interface [polypeptide binding]; other site
1030843000174	allosteric regulatory binding pocket; other site
1030843000175	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1030843000176	dimer interface [polypeptide binding]; other site
1030843000177	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1030843000178	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1030843000179	active site
1030843000180	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1030843000181	substrate binding site [chemical binding]; other site
1030843000182	catalytic residues [active]
1030843000183	dimer interface [polypeptide binding]; other site
1030843000184	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1030843000185	UbiA prenyltransferase family; Region: UbiA; pfam01040
1030843000186	Penicillinase repressor; Region: Pencillinase_R; pfam03965
1030843000187	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1030843000188	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1030843000189	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1030843000190	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843000191	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843000192	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843000193	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843000194	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843000195	Domain of unknown function (DUF2436); Region: DUF2436; pfam10365
1030843000196	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000197	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000198	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000199	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000200	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000201	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000202	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000203	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000204	nucleoside transporter; Region: 2A0110; TIGR00889
1030843000205	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
1030843000206	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
1030843000207	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843000208	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1030843000209	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1030843000210	ATP binding site [chemical binding]; other site
1030843000211	putative Mg++ binding site [ion binding]; other site
1030843000212	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843000213	nucleotide binding region [chemical binding]; other site
1030843000214	ATP-binding site [chemical binding]; other site
1030843000215	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1030843000216	AMP-binding enzyme; Region: AMP-binding; pfam00501
1030843000217	acyl-activating enzyme (AAE) consensus motif; other site
1030843000218	putative AMP binding site [chemical binding]; other site
1030843000219	putative active site [active]
1030843000220	putative CoA binding site [chemical binding]; other site
1030843000221	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1030843000222	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1030843000223	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1030843000224	DNA binding residues [nucleotide binding]
1030843000225	Protein of unknown function (DUF1232); Region: DUF1232; cl01318
1030843000226	enolase; Provisional; Region: eno; PRK00077
1030843000227	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1030843000228	dimer interface [polypeptide binding]; other site
1030843000229	metal binding site [ion binding]; metal-binding site
1030843000230	substrate binding pocket [chemical binding]; other site
1030843000231	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1030843000232	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
1030843000233	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1030843000234	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1030843000235	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
1030843000236	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1030843000237	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1030843000238	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1030843000239	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1030843000240	Ligand binding site; other site
1030843000241	oligomer interface; other site
1030843000242	DNA primase, catalytic core; Region: dnaG; TIGR01391
1030843000243	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1030843000244	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1030843000245	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1030843000246	active site
1030843000247	metal binding site [ion binding]; metal-binding site
1030843000248	interdomain interaction site; other site
1030843000249	Ferredoxin [Energy production and conversion]; Region: COG1146
1030843000250	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
1030843000251	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1030843000252	dimer interface [polypeptide binding]; other site
1030843000253	PYR/PP interface [polypeptide binding]; other site
1030843000254	TPP binding site [chemical binding]; other site
1030843000255	substrate binding site [chemical binding]; other site
1030843000256	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1030843000257	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
1030843000258	TPP-binding site [chemical binding]; other site
1030843000259	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
1030843000260	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
1030843000261	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1030843000262	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1030843000263	Zn2+ binding site [ion binding]; other site
1030843000264	Mg2+ binding site [ion binding]; other site
1030843000265	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1030843000266	synthetase active site [active]
1030843000267	NTP binding site [chemical binding]; other site
1030843000268	metal binding site [ion binding]; metal-binding site
1030843000269	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1030843000270	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1030843000271	V-type ATP synthase subunit K; Validated; Region: PRK06558
1030843000272	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
1030843000273	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
1030843000274	V-type ATP synthase subunit I; Validated; Region: PRK05771
1030843000275	V-type ATP synthase subunit D; Provisional; Region: PRK02195
1030843000276	V-type ATP synthase subunit B; Provisional; Region: PRK02118
1030843000277	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1030843000278	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
1030843000279	Walker A motif homologous position; other site
1030843000280	Walker B motif; other site
1030843000281	V-type ATP synthase subunit A; Provisional; Region: PRK04192
1030843000282	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1030843000283	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
1030843000284	Walker A motif/ATP binding site; other site
1030843000285	Walker B motif; other site
1030843000286	Protein of unknown function (DUF2764); Region: DUF2764; pfam10962
1030843000287	V-type ATP synthase subunit E; Provisional; Region: PRK01558
1030843000288	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843000289	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843000290	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843000291	binding surface
1030843000292	TPR motif; other site
1030843000293	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843000294	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1030843000295	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1030843000296	dimer interface [polypeptide binding]; other site
1030843000297	phosphorylation site [posttranslational modification]
1030843000298	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843000299	ATP binding site [chemical binding]; other site
1030843000300	Mg2+ binding site [ion binding]; other site
1030843000301	G-X-G motif; other site
1030843000302	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1030843000303	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1030843000304	active site
1030843000305	phosphorylation site [posttranslational modification]
1030843000306	intermolecular recognition site; other site
1030843000307	dimerization interface [polypeptide binding]; other site
1030843000308	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1030843000309	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1030843000310	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843000311	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843000312	DNA polymerase I; Provisional; Region: PRK05755
1030843000313	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1030843000314	active site
1030843000315	metal binding site 1 [ion binding]; metal-binding site
1030843000316	putative 5' ssDNA interaction site; other site
1030843000317	metal binding site 3; metal-binding site
1030843000318	metal binding site 2 [ion binding]; metal-binding site
1030843000319	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1030843000320	putative DNA binding site [nucleotide binding]; other site
1030843000321	putative metal binding site [ion binding]; other site
1030843000322	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1030843000323	active site
1030843000324	catalytic site [active]
1030843000325	substrate binding site [chemical binding]; other site
1030843000326	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1030843000327	active site
1030843000328	DNA binding site [nucleotide binding]
1030843000329	catalytic site [active]
1030843000330	N-terminal Early set domain associated with the catalytic domain of eukaryotic glycogen branching enzyme (also called 1,4 alpha glucan branching enzyme); Region: E_set_GBE_euk_N; cd02854
1030843000331	1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism]; Region: GlgB; COG0296
1030843000332	Alpha amylase catalytic domain found in bacterial and eukaryotic branching enzymes; Region: AmyAc_bac_euk_BE; cd11321
1030843000333	active site
1030843000334	catalytic site [active]
1030843000335	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1030843000336	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1030843000337	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1030843000338	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
1030843000339	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
1030843000340	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1030843000341	active site
1030843000342	Zn binding site [ion binding]; other site
1030843000343	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cl00298
1030843000344	active site
1030843000345	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1030843000346	homotrimer interaction site [polypeptide binding]; other site
1030843000347	putative active site [active]
1030843000348	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1030843000349	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1030843000350	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1030843000351	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1030843000352	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1030843000353	Walker A/P-loop; other site
1030843000354	ATP binding site [chemical binding]; other site
1030843000355	Q-loop/lid; other site
1030843000356	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1030843000357	ABC transporter signature motif; other site
1030843000358	Walker B; other site
1030843000359	D-loop; other site
1030843000360	H-loop/switch region; other site
1030843000361	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1030843000362	Flavoprotein; Region: Flavoprotein; pfam02441
1030843000363	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1030843000364	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1030843000365	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1030843000366	active site
1030843000367	catalytic site [active]
1030843000368	substrate binding site [chemical binding]; other site
1030843000369	DNA polymerase III subunit beta; Validated; Region: PRK05643
1030843000370	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1030843000371	putative DNA binding surface [nucleotide binding]; other site
1030843000372	dimer interface [polypeptide binding]; other site
1030843000373	beta-clamp/clamp loader binding surface; other site
1030843000374	beta-clamp/translesion DNA polymerase binding surface; other site
1030843000375	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843000376	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843000377	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1030843000378	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1030843000379	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1030843000380	C-terminal peptidase (prc); Region: prc; TIGR00225
1030843000381	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1030843000382	protein binding site [polypeptide binding]; other site
1030843000383	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1030843000384	Catalytic dyad [active]
1030843000385	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
1030843000386	catalytic motif [active]
1030843000387	Zn binding site [ion binding]; other site
1030843000388	Protein of unknown function (DUF2023); Region: DUF2023; pfam09633
1030843000389	flavodoxin FldA; Validated; Region: PRK09267
1030843000390	glycerate kinase; Region: TIGR00045
1030843000391	AAA domain; Region: AAA_14; pfam13173
1030843000392	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1030843000393	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1030843000394	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000395	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000396	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1030843000397	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000398	Leucine-rich repeats; other site
1030843000399	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000400	Substrate binding site [chemical binding]; other site
1030843000401	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000402	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000403	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000404	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000405	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1030843000406	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000407	Leucine-rich repeats; other site
1030843000408	Substrate binding site [chemical binding]; other site
1030843000409	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843000410	Leucine rich repeat; Region: LRR_8; pfam13855
1030843000411	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1030843000412	G1 box; other site
1030843000413	GTP/Mg2+ binding site [chemical binding]; other site
1030843000414	G2 box; other site
1030843000415	Switch I region; other site
1030843000416	G3 box; other site
1030843000417	Switch II region; other site
1030843000418	TIR domain; Region: TIR_2; pfam13676
1030843000419	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1755
1030843000420	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843000421	S-adenosylmethionine binding site [chemical binding]; other site
1030843000422	urocanate hydratase; Provisional; Region: PRK05414
1030843000423	hypothetical protein; Reviewed; Region: PRK12497
1030843000424	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1030843000425	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
1030843000426	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1030843000427	putative acyl-acceptor binding pocket; other site
1030843000428	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
1030843000429	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1030843000430	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1030843000431	active site
1030843000432	HIGH motif; other site
1030843000433	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1030843000434	KMSKS motif; other site
1030843000435	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1030843000436	tRNA binding surface [nucleotide binding]; other site
1030843000437	anticodon binding site; other site
1030843000438	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
1030843000439	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1030843000440	active site
1030843000441	nucleophile elbow; other site
1030843000442	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1030843000443	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1030843000444	active site
1030843000445	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1030843000446	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1030843000447	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
1030843000448	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1030843000449	polyphosphate kinase; Provisional; Region: PRK05443
1030843000450	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1030843000451	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1030843000452	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
1030843000453	domain interface [polypeptide binding]; other site
1030843000454	active site
1030843000455	catalytic site [active]
1030843000456	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1030843000457	domain interface [polypeptide binding]; other site
1030843000458	active site
1030843000459	catalytic site [active]
1030843000460	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1030843000461	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1030843000462	HflX GTPase family; Region: HflX; cd01878
1030843000463	G1 box; other site
1030843000464	GTP/Mg2+ binding site [chemical binding]; other site
1030843000465	Switch I region; other site
1030843000466	G2 box; other site
1030843000467	G3 box; other site
1030843000468	Switch II region; other site
1030843000469	G4 box; other site
1030843000470	G5 box; other site
1030843000471	tRNA 2-selenouridine synthase; Region: tRNA_sel_U_synt; TIGR03167
1030843000472	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1030843000473	active site residue [active]
1030843000474	SirA-like protein; Region: SirA; pfam01206
1030843000475	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
1030843000476	DsrE/DsrF-like family; Region: DrsE; pfam02635
1030843000477	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843000478	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
1030843000479	Family description; Region: VCBS; pfam13517
1030843000480	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1030843000481	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1030843000482	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1030843000483	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1030843000484	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1030843000485	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1030843000486	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1030843000487	Thiamine pyrophosphokinase; Region: TPK; cd07995
1030843000488	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
1030843000489	active site
1030843000490	dimerization interface [polypeptide binding]; other site
1030843000491	thiamine binding site [chemical binding]; other site
1030843000492	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
1030843000493	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1030843000494	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843000495	GTPase RsgA; Reviewed; Region: PRK00098
1030843000496	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1030843000497	RNA binding site [nucleotide binding]; other site
1030843000498	homodimer interface [polypeptide binding]; other site
1030843000499	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1030843000500	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1030843000501	GTP/Mg2+ binding site [chemical binding]; other site
1030843000502	G4 box; other site
1030843000503	G5 box; other site
1030843000504	G1 box; other site
1030843000505	Switch I region; other site
1030843000506	G2 box; other site
1030843000507	G3 box; other site
1030843000508	Switch II region; other site
1030843000509	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1030843000510	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1030843000511	hinge region; other site
1030843000512	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1030843000513	putative nucleotide binding site [chemical binding]; other site
1030843000514	uridine monophosphate binding site [chemical binding]; other site
1030843000515	homohexameric interface [polypeptide binding]; other site
1030843000516	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843000517	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843000518	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843000519	GLPGLI family protein; Region: GLPGLI; TIGR01200
1030843000520	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843000521	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843000522	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843000523	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1030843000524	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1030843000525	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1030843000526	alphaNTD - beta interaction site [polypeptide binding]; other site
1030843000527	alphaNTD homodimer interface [polypeptide binding]; other site
1030843000528	alphaNTD - beta' interaction site [polypeptide binding]; other site
1030843000529	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1030843000530	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1030843000531	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1030843000532	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1030843000533	RNA binding surface [nucleotide binding]; other site
1030843000534	30S ribosomal protein S11; Validated; Region: PRK05309
1030843000535	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1030843000536	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1030843000537	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1030843000538	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1030843000539	rRNA binding site [nucleotide binding]; other site
1030843000540	predicted 30S ribosome binding site; other site
1030843000541	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1030843000542	active site
1030843000543	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1030843000544	SecY translocase; Region: SecY; pfam00344
1030843000545	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1030843000546	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1030843000547	23S rRNA binding site [nucleotide binding]; other site
1030843000548	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1030843000549	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1030843000550	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1030843000551	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1030843000552	5S rRNA interface [nucleotide binding]; other site
1030843000553	L27 interface [polypeptide binding]; other site
1030843000554	23S rRNA interface [nucleotide binding]; other site
1030843000555	L5 interface [polypeptide binding]; other site
1030843000556	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1030843000557	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1030843000558	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1030843000559	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1030843000560	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1030843000561	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1030843000562	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1030843000563	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1030843000564	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1030843000565	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1030843000566	RNA binding site [nucleotide binding]; other site
1030843000567	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1030843000568	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1030843000569	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1030843000570	23S rRNA interface [nucleotide binding]; other site
1030843000571	putative translocon interaction site; other site
1030843000572	signal recognition particle (SRP54) interaction site; other site
1030843000573	L23 interface [polypeptide binding]; other site
1030843000574	trigger factor interaction site; other site
1030843000575	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1030843000576	23S rRNA interface [nucleotide binding]; other site
1030843000577	5S rRNA interface [nucleotide binding]; other site
1030843000578	putative antibiotic binding site [chemical binding]; other site
1030843000579	L25 interface [polypeptide binding]; other site
1030843000580	L27 interface [polypeptide binding]; other site
1030843000581	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1030843000582	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1030843000583	G-X-X-G motif; other site
1030843000584	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1030843000585	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1030843000586	putative translocon binding site; other site
1030843000587	protein-rRNA interface [nucleotide binding]; other site
1030843000588	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1030843000589	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1030843000590	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1030843000591	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1030843000592	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1030843000593	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1030843000594	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1030843000595	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1030843000596	elongation factor G; Reviewed; Region: PRK12739
1030843000597	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1030843000598	G1 box; other site
1030843000599	putative GEF interaction site [polypeptide binding]; other site
1030843000600	GTP/Mg2+ binding site [chemical binding]; other site
1030843000601	Switch I region; other site
1030843000602	G2 box; other site
1030843000603	G3 box; other site
1030843000604	Switch II region; other site
1030843000605	G4 box; other site
1030843000606	G5 box; other site
1030843000607	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1030843000608	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1030843000609	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1030843000610	30S ribosomal protein S7; Validated; Region: PRK05302
1030843000611	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1030843000612	S17 interaction site [polypeptide binding]; other site
1030843000613	S8 interaction site; other site
1030843000614	16S rRNA interaction site [nucleotide binding]; other site
1030843000615	streptomycin interaction site [chemical binding]; other site
1030843000616	23S rRNA interaction site [nucleotide binding]; other site
1030843000617	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1030843000618	Protein of unknown function (DUF3667); Region: DUF3667; pfam12412
1030843000619	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1030843000620	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
1030843000621	putative active site [active]
1030843000622	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1030843000623	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1030843000624	ABC-ATPase subunit  interface; other site
1030843000625	dimer interface [polypeptide binding]; other site
1030843000626	putative PBP binding regions; other site
1030843000627	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1030843000628	binding surface
1030843000629	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1030843000630	TPR motif; other site
1030843000631	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1030843000632	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1030843000633	Malate/lactate dehydrogenases [Energy production and conversion]; Region: Mdh; COG0039
1030843000634	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1030843000635	NAD(P) binding site [chemical binding]; other site
1030843000636	LDH/MDH dimer interface [polypeptide binding]; other site
1030843000637	substrate binding site [chemical binding]; other site
1030843000638	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1030843000639	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1030843000640	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1030843000641	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1030843000642	active site
1030843000643	HIGH motif; other site
1030843000644	nucleotide binding site [chemical binding]; other site
1030843000645	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1030843000646	KMSKS motif; other site
1030843000647	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1030843000648	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1030843000649	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1030843000650	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1030843000651	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1030843000652	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1030843000653	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1030843000654	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1030843000655	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1030843000656	NAD(P) binding site [chemical binding]; other site
1030843000657	active site
1030843000658	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
1030843000659	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1030843000660	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1030843000661	Domain of unknown function (DUF4295); Region: DUF4295; pfam14128
1030843000662	ribosomal protein L33; Region: rpl33; CHL00104
1030843000663	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1030843000664	Phosphate transporter family; Region: PHO4; cl00396
1030843000665	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843000666	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1030843000667	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1030843000668	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1030843000669	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1030843000670	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1030843000671	Cl- selectivity filter; other site
1030843000672	Cl- binding residues [ion binding]; other site
1030843000673	pore gating glutamate residue; other site
1030843000674	dimer interface [polypeptide binding]; other site
1030843000675	FOG: CBS domain [General function prediction only]; Region: COG0517
1030843000676	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc2; cd04613
1030843000677	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1030843000678	TPR repeat; Region: TPR_11; pfam13414
1030843000679	TPR repeat; Region: TPR_11; pfam13414
1030843000680	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843000681	binding surface
1030843000682	TPR motif; other site
1030843000683	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843000684	binding surface
1030843000685	TPR motif; other site
1030843000686	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843000687	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1030843000688	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
1030843000689	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
1030843000690	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1030843000691	putative active site [active]
1030843000692	putative NTP binding site [chemical binding]; other site
1030843000693	putative nucleic acid binding site [nucleotide binding]; other site
1030843000694	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cd09634
1030843000695	CRISPR/Cas system-associated RAMP superfamily protein Cmr6; Region: Cmr6_III-B; cd09661
1030843000696	CRISPR/Cas system-associated RAMP superfamily protein Cmr4; Region: Cmr4_III-B; cd09682
1030843000697	CRISPR/Cas system-associated RAMP superfamily protein Cmr3; Region: Cmr3_III-B; cl12075
1030843000698	CRISPR-associated protein (Cas_Cmr3); Region: Cas_Cmr3; pfam09700
1030843000699	CRISPR-associated protein Cas10/Cmr2, subtype III-B; Region: cas_TM1794_Cmr2; TIGR02577
1030843000700	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cl13853
1030843000701	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1030843000702	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1030843000703	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1030843000704	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1030843000705	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1030843000706	GIY-YIG motif/motif A; other site
1030843000707	active site
1030843000708	catalytic site [active]
1030843000709	putative DNA binding site [nucleotide binding]; other site
1030843000710	metal binding site [ion binding]; metal-binding site
1030843000711	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1030843000712	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1030843000713	putative active site [active]
1030843000714	dimerization interface [polypeptide binding]; other site
1030843000715	putative tRNAtyr binding site [nucleotide binding]; other site
1030843000716	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
1030843000717	homodimer interface [polypeptide binding]; other site
1030843000718	metal binding site [ion binding]; metal-binding site
1030843000719	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1030843000720	intersubunit interface [polypeptide binding]; other site
1030843000721	active site
1030843000722	catalytic residue [active]
1030843000723	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1030843000724	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1030843000725	substrate binding pocket [chemical binding]; other site
1030843000726	chain length determination region; other site
1030843000727	substrate-Mg2+ binding site; other site
1030843000728	catalytic residues [active]
1030843000729	aspartate-rich region 1; other site
1030843000730	active site lid residues [active]
1030843000731	aspartate-rich region 2; other site
1030843000732	WbqC-like protein family; Region: WbqC; pfam08889
1030843000733	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cd06462
1030843000734	Catalytic site [active]
1030843000735	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1030843000736	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
1030843000737	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1030843000738	Catalytic site [active]
1030843000739	conjugal transfer peptidase TraF; Provisional; Region: PRK13884
1030843000740	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1030843000741	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1030843000742	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1030843000743	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1030843000744	deoxyguanosinetriphosphate triphosphohydrolase, putative; Region: dGTP_triPase; TIGR01353
1030843000745	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1030843000746	Predicted membrane protein [Function unknown]; Region: COG2855
1030843000747	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843000748	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1030843000749	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1030843000750	N-terminal plug; other site
1030843000751	ligand-binding site [chemical binding]; other site
1030843000752	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1030843000753	Recombination protein O N terminal; Region: RecO_N; pfam11967
1030843000754	Recombination protein O C terminal; Region: RecO_C; pfam02565
1030843000755	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1030843000756	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1030843000757	active site
1030843000758	substrate binding site [chemical binding]; other site
1030843000759	metal binding site [ion binding]; metal-binding site
1030843000760	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843000761	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843000762	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843000763	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843000764	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843000765	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843000766	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
1030843000767	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-B; cd09722
1030843000768	Domain of unknown function DUF83; Region: Cas_Cas4; pfam01930
1030843000769	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1030843000770	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
1030843000771	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
1030843000772	CRISPR-associated autoregulator DevR family; Region: cas_MJ0381; TIGR01875
1030843000773	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I; cd09717
1030843000774	CRISPR/Cas system-associated protein Cas8c; Region: Csp2_I-U; cl11894
1030843000775	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cd09716
1030843000776	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
1030843000777	Sulfatase; Region: Sulfatase; pfam00884
1030843000778	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
1030843000779	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1030843000780	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1030843000781	putative active site [active]
1030843000782	substrate binding site [chemical binding]; other site
1030843000783	putative cosubstrate binding site; other site
1030843000784	catalytic site [active]
1030843000785	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1030843000786	substrate binding site [chemical binding]; other site
1030843000787	Propeptide_C25; Region: Propeptide_C25; pfam08126
1030843000788	gingipain subgroup of the Peptidase C25 family N-terminal domain; Region: Peptidase_C25_N_gingipain; cd10913
1030843000789	active site
1030843000790	Peptidase family C25, C terminal ig-like domain; Region: Peptidase_C25_C; pfam03785
1030843000791	Domain of unknown function (DUF2436); Region: DUF2436; pfam10365
1030843000792	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000793	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843000794	Domain of unknown function (DUF2436); Region: DUF2436; pfam10365
1030843000795	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843000796	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1030843000797	catalytic core [active]
1030843000798	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1030843000799	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1030843000800	putative deacylase active site [active]
1030843000801	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
1030843000802	active site
1030843000803	Domain of unknown function (DUF4294); Region: DUF4294; pfam14127
1030843000804	hydrophobic ligand binding site; other site
1030843000805	Activator of Hsp90 ATPase homolog 1-like protein; Region: AHSA1; pfam08327
1030843000806	primosome assembly protein PriA; Validated; Region: PRK05580
1030843000807	putative oxidoreductase; Provisional; Region: PRK12831
1030843000808	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1030843000809	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1030843000810	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1030843000811	ferredoxin-NADP(+) reductase subunit alpha; Reviewed; Region: PRK06222
1030843000812	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219
1030843000813	FAD binding pocket [chemical binding]; other site
1030843000814	FAD binding motif [chemical binding]; other site
1030843000815	phosphate binding motif [ion binding]; other site
1030843000816	beta-alpha-beta structure motif; other site
1030843000817	NAD binding pocket [chemical binding]; other site
1030843000818	Iron coordination center [ion binding]; other site
1030843000819	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1030843000820	Ion transport protein; Region: Ion_trans; pfam00520
1030843000821	Ion channel; Region: Ion_trans_2; pfam07885
1030843000822	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1030843000823	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1030843000824	amidase catalytic site [active]
1030843000825	Zn binding residues [ion binding]; other site
1030843000826	substrate binding site [chemical binding]; other site
1030843000827	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843000828	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1030843000829	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1030843000830	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1030843000831	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1030843000832	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1030843000833	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
1030843000834	Putative zinc ribbon domain; Region: DUF164; pfam02591
1030843000835	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1030843000836	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1030843000837	Ligand Binding Site [chemical binding]; other site
1030843000838	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1030843000839	PIF1-like helicase; Region: PIF1; pfam05970
1030843000840	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843000841	Walker A motif; other site
1030843000842	ATP binding site [chemical binding]; other site
1030843000843	Walker B motif; other site
1030843000844	Family description; Region: UvrD_C_2; pfam13538
1030843000845	Dehydratase family; Region: ILVD_EDD; cl00340
1030843000846	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1030843000847	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1030843000848	dimer interface [polypeptide binding]; other site
1030843000849	active site
1030843000850	catalytic residue [active]
1030843000851	AAA domain; Region: AAA_26; pfam13500
1030843000852	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1030843000853	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1030843000854	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1030843000855	ligand binding site [chemical binding]; other site
1030843000856	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK07565
1030843000857	Dihydroorotate dehydrogenase (DHOD) like proteins. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD...; Region: DHOD_like; cd04739
1030843000858	putative active site [active]
1030843000859	putative FMN binding site [chemical binding]; other site
1030843000860	putative substrate binding site [chemical binding]; other site
1030843000861	partial transposase in ISPg2; similar to nr, gi|188995258|ref|YP_001929510.1| transposase in ISPg2 [Porphyromonas gingivalis ATCC 33277] transposase in ISPg2 [Porphyromonas gingivalis ATCC 33277], percent identity 47.7 in 88 aa, BLASTP E(): 3e-13
1030843000862	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1030843000863	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843000864	ATP binding site [chemical binding]; other site
1030843000865	Mg2+ binding site [ion binding]; other site
1030843000866	G-X-G motif; other site
1030843000867	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1030843000868	DHH family; Region: DHH; pfam01368
1030843000869	DHHA1 domain; Region: DHHA1; pfam02272
1030843000870	PspC domain; Region: PspC; pfam04024
1030843000871	DivIVA protein; Region: DivIVA; pfam05103
1030843000872	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1030843000873	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1030843000874	active site
1030843000875	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1030843000876	nicotinate (nicotinamide) nucleotide adenylyltransferase; Region: TIGR00482
1030843000877	active site
1030843000878	(T/H)XGH motif; other site
1030843000879	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
1030843000880	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
1030843000881	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1030843000882	PIF1-like helicase; Region: PIF1; pfam05970
1030843000883	AAA domain; Region: AAA_30; pfam13604
1030843000884	Family description; Region: UvrD_C_2; pfam13538
1030843000885	TPR repeat; Region: TPR_11; pfam13414
1030843000886	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843000887	TPR motif; other site
1030843000888	binding surface
1030843000889	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1030843000890	Outer membrane efflux protein; Region: OEP; pfam02321
1030843000891	Outer membrane efflux protein; Region: OEP; pfam02321
1030843000892	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1030843000893	Protein export membrane protein; Region: SecD_SecF; cl14618
1030843000894	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1030843000895	HlyD family secretion protein; Region: HlyD_3; pfam13437
1030843000896	putative carbohydrate kinase; Provisional; Region: PRK10565
1030843000897	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
1030843000898	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1030843000899	putative substrate binding site [chemical binding]; other site
1030843000900	putative ATP binding site [chemical binding]; other site
1030843000901	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1030843000902	acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Region: lipid_A_lpxA; TIGR01852
1030843000903	active site
1030843000904	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
1030843000905	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1030843000906	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1030843000907	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1030843000908	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1030843000909	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1030843000910	trimer interface [polypeptide binding]; other site
1030843000911	active site
1030843000912	UDP-GlcNAc binding site [chemical binding]; other site
1030843000913	lipid binding site [chemical binding]; lipid-binding site
1030843000914	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1030843000915	active site
1030843000916	dimer interface [polypeptide binding]; other site
1030843000917	Protein of unknown function (DUF327); Region: DUF327; cl00753
1030843000918	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1030843000919	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1030843000920	RF-1 domain; Region: RF-1; pfam00472
1030843000921	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1030843000922	dimerization interface [polypeptide binding]; other site
1030843000923	ATP binding site [chemical binding]; other site
1030843000924	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
1030843000925	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1030843000926	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1030843000927	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1030843000928	RloB-like protein; Region: RloB; pfam13707
1030843000929	Bacterial Ig-like domain; Region: Big_5; pfam13205
1030843000930	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1030843000931	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
1030843000932	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1030843000933	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1030843000934	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1030843000935	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1030843000936	alpha-galactosidase; Region: PLN02808; cl17638
1030843000937	potential frameshift: common BLAST hit: gi|34539956|ref|NP_904435.1| DEAD-box ATP dependent DNA helicase
1030843000938	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
1030843000939	RNA binding site [nucleotide binding]; other site
1030843000940	helicase 45; Provisional; Region: PTZ00424
1030843000941	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1030843000942	ATP binding site [chemical binding]; other site
1030843000943	Mg++ binding site [ion binding]; other site
1030843000944	motif III; other site
1030843000945	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843000946	nucleotide binding region [chemical binding]; other site
1030843000947	ATP-binding site [chemical binding]; other site
1030843000948	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1030843000949	putative active site [active]
1030843000950	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1030843000951	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1030843000952	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1030843000953	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1030843000954	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1030843000955	dimerization interface [polypeptide binding]; other site
1030843000956	DPS ferroxidase diiron center [ion binding]; other site
1030843000957	ion pore; other site
1030843000958	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1030843000959	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1030843000960	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1030843000961	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1030843000962	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1030843000963	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1030843000964	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1030843000965	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1030843000966	HlyD family secretion protein; Region: HlyD_3; pfam13437
1030843000967	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1030843000968	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1030843000969	MutS domain I; Region: MutS_I; pfam01624
1030843000970	MutS domain II; Region: MutS_II; pfam05188
1030843000971	MutS domain III; Region: MutS_III; pfam05192
1030843000972	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1030843000973	Walker A/P-loop; other site
1030843000974	ATP binding site [chemical binding]; other site
1030843000975	Q-loop/lid; other site
1030843000976	ABC transporter signature motif; other site
1030843000977	Walker B; other site
1030843000978	D-loop; other site
1030843000979	H-loop/switch region; other site
1030843000980	hypothetical protein; Provisional; Region: PRK12378
1030843000981	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1030843000982	putative tRNA-binding site [nucleotide binding]; other site
1030843000983	Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Region: PheT; COG0072
1030843000984	B3/4 domain; Region: B3_4; pfam03483
1030843000985	tRNA synthetase B5 domain; Region: B5; pfam03484
1030843000986	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1030843000987	dimer interface [polypeptide binding]; other site
1030843000988	motif 1; other site
1030843000989	motif 3; other site
1030843000990	motif 2; other site
1030843000991	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1030843000992	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843000993	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843000994	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843000995	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843000996	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843000997	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
1030843000998	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1030843000999	active site
1030843001000	putative interdomain interaction site [polypeptide binding]; other site
1030843001001	putative metal-binding site [ion binding]; other site
1030843001002	putative nucleotide binding site [chemical binding]; other site
1030843001003	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1030843001004	domain I; other site
1030843001005	DNA binding groove [nucleotide binding]
1030843001006	phosphate binding site [ion binding]; other site
1030843001007	domain II; other site
1030843001008	domain III; other site
1030843001009	nucleotide binding site [chemical binding]; other site
1030843001010	catalytic site [active]
1030843001011	domain IV; other site
1030843001012	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1030843001013	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1030843001014	Mg++ binding site [ion binding]; other site
1030843001015	putative catalytic motif [active]
1030843001016	substrate binding site [chemical binding]; other site
1030843001017	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1030843001018	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1030843001019	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1030843001020	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1030843001021	active site
1030843001022	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1030843001023	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1030843001024	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
1030843001025	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1030843001026	acyl-activating enzyme (AAE) consensus motif; other site
1030843001027	active site
1030843001028	AMP binding site [chemical binding]; other site
1030843001029	CoA binding site [chemical binding]; other site
1030843001030	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843001031	putative acyl transferase; Provisional; Region: PRK10191
1030843001032	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1030843001033	active site
1030843001034	substrate binding site [chemical binding]; other site
1030843001035	trimer interface [polypeptide binding]; other site
1030843001036	CoA binding site [chemical binding]; other site
1030843001037	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
1030843001038	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1030843001039	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1030843001040	active site
1030843001041	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1030843001042	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1030843001043	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1030843001044	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1030843001045	active site
1030843001046	homodimer interface [polypeptide binding]; other site
1030843001047	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1030843001048	IHF - DNA interface [nucleotide binding]; other site
1030843001049	IHF dimer interface [polypeptide binding]; other site
1030843001050	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1030843001051	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1030843001052	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1030843001053	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1030843001054	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
1030843001055	ferrochelatase; Reviewed; Region: hemH; PRK00035
1030843001056	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1030843001057	C-terminal domain interface [polypeptide binding]; other site
1030843001058	active site
1030843001059	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1030843001060	active site
1030843001061	N-terminal domain interface [polypeptide binding]; other site
1030843001062	Lipopolysaccharide kinase (Kdo/WaaP) family; Region: Kdo; cl17488
1030843001063	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1030843001064	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1030843001065	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1030843001066	catalytic core [active]
1030843001067	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1030843001068	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1030843001069	MgtE intracellular N domain; Region: MgtE_N; smart00924
1030843001070	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1030843001071	Divalent cation transporter; Region: MgtE; pfam01769
1030843001072	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1030843001073	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1030843001074	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1030843001075	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1030843001076	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1030843001077	metal binding site [ion binding]; metal-binding site
1030843001078	dimer interface [polypeptide binding]; other site
1030843001079	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1030843001080	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1030843001081	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1030843001082	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1030843001083	catalytic residue [active]
1030843001084	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1030843001085	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1030843001086	ParB-like nuclease domain; Region: ParBc; pfam02195
1030843001087	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1030843001088	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1030843001089	P-loop; other site
1030843001090	Magnesium ion binding site [ion binding]; other site
1030843001091	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1030843001092	Magnesium ion binding site [ion binding]; other site
1030843001093	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
1030843001094	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
1030843001095	putative active site; other site
1030843001096	catalytic triad [active]
1030843001097	putative dimer interface [polypeptide binding]; other site
1030843001098	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1030843001099	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
1030843001100	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1030843001101	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843001102	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1030843001103	Walker A motif; other site
1030843001104	ATP binding site [chemical binding]; other site
1030843001105	Walker B motif; other site
1030843001106	arginine finger; other site
1030843001107	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1030843001108	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1030843001109	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
1030843001110	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1030843001111	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843001112	FeS/SAM binding site; other site
1030843001113	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1030843001114	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1030843001115	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1030843001116	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
1030843001117	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
1030843001118	dimer interface [polypeptide binding]; other site
1030843001119	active site
1030843001120	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1030843001121	catalytic residues [active]
1030843001122	substrate binding site [chemical binding]; other site
1030843001123	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1030843001124	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1030843001125	dimer interface [polypeptide binding]; other site
1030843001126	anticodon binding site; other site
1030843001127	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1030843001128	homodimer interface [polypeptide binding]; other site
1030843001129	motif 1; other site
1030843001130	active site
1030843001131	motif 2; other site
1030843001132	GAD domain; Region: GAD; pfam02938
1030843001133	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1030843001134	motif 3; other site
1030843001135	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1030843001136	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1030843001137	catalytic motif [active]
1030843001138	Zn binding site [ion binding]; other site
1030843001139	RibD C-terminal domain; Region: RibD_C; pfam01872
1030843001140	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1030843001141	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843001142	S-adenosylmethionine binding site [chemical binding]; other site
1030843001143	RecX family; Region: RecX; pfam02631
1030843001144	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1030843001145	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1030843001146	active site
1030843001147	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1030843001148	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1030843001149	active site
1030843001150	Zn binding site [ion binding]; other site
1030843001151	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1030843001152	active site
1030843001153	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1030843001154	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1030843001155	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1030843001156	DNA binding residues [nucleotide binding]
1030843001157	diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional; Region: PRK07085
1030843001158	pyrophosphate-dependent phosphofructokinase; Region: PLN02251
1030843001159	active site
1030843001160	ADP/pyrophosphate binding site [chemical binding]; other site
1030843001161	dimerization interface [polypeptide binding]; other site
1030843001162	allosteric effector site; other site
1030843001163	fructose-1,6-bisphosphate binding site; other site
1030843001164	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
1030843001165	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1030843001166	RNA binding surface [nucleotide binding]; other site
1030843001167	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1030843001168	putative active site [active]
1030843001169	catalytic residue [active]
1030843001170	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1030843001171	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1030843001172	5S rRNA interface [nucleotide binding]; other site
1030843001173	CTC domain interface [polypeptide binding]; other site
1030843001174	L16 interface [polypeptide binding]; other site
1030843001175	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1030843001176	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1030843001177	active site
1030843001178	HIGH motif; other site
1030843001179	KMSKS motif; other site
1030843001180	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1030843001181	tRNA binding surface [nucleotide binding]; other site
1030843001182	anticodon binding site; other site
1030843001183	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1030843001184	dimer interface [polypeptide binding]; other site
1030843001185	putative tRNA-binding site [nucleotide binding]; other site
1030843001186	2',3'-cyclic-nucleotide 2'-phosphodiesterase; Region: CycNucDiestase; TIGR01390
1030843001187	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1030843001188	active site
1030843001189	metal binding site [ion binding]; metal-binding site
1030843001190	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1030843001191	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1030843001192	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1030843001193	active site
1030843001194	catalytic site [active]
1030843001195	substrate binding site [chemical binding]; other site
1030843001196	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1030843001197	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
1030843001198	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1030843001199	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1030843001200	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1030843001201	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
1030843001202	active site residue [active]
1030843001203	SirA_RHOD_Pry_redox.    SirA-like domain located within a multidomain protein of unknown function. Other domains include RHOD (rhodanese homology domain), and Pry_redox (pyridine nucleotide-disulphide oxidoreductase) as well as a C-terminal domain that...; Region: SirA_RHOD_Pry_redox; cd03420
1030843001204	CPxP  motif; other site
1030843001205	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
1030843001206	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
1030843001207	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
1030843001208	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
1030843001209	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
1030843001210	Chordopoxvirus A20R protein; Region: Chordopox_A20R; pfam05941
1030843001211	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
1030843001212	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843001213	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1030843001214	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
1030843001215	starch binding outer membrane protein SusD; Region: SusD; cd08977
1030843001216	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14836
1030843001217	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1030843001218	catalytic residue [active]
1030843001219	putative FPP diphosphate  binding site; other site
1030843001220	putative FPP binding hydrophobic cleft; other site
1030843001221	dimer interface [polypeptide binding]; other site
1030843001222	putative IPP diphosphate binding site; other site
1030843001223	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
1030843001224	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1030843001225	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1030843001226	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1030843001227	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1030843001228	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1030843001229	Surface antigen; Region: Bac_surface_Ag; pfam01103
1030843001230	periplasmic chaperone; Provisional; Region: PRK10780
1030843001231	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1030843001232	periplasmic chaperone; Provisional; Region: PRK10780
1030843001233	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1030843001234	Rubrerythrin [Energy production and conversion]; Region: COG1592
1030843001235	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1030843001236	binuclear metal center [ion binding]; other site
1030843001237	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
1030843001238	iron binding site [ion binding]; other site
1030843001239	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1030843001240	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1030843001241	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1030843001242	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1030843001243	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1030843001244	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1030843001245	active site
1030843001246	hypothetical protein; Validated; Region: PRK00041
1030843001247	ribonuclease P; Reviewed; Region: rnpA; PRK01903
1030843001248	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1030843001249	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1030843001250	active site
1030843001251	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
1030843001252	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1030843001253	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1030843001254	G1 box; other site
1030843001255	putative GEF interaction site [polypeptide binding]; other site
1030843001256	GTP/Mg2+ binding site [chemical binding]; other site
1030843001257	Switch I region; other site
1030843001258	G2 box; other site
1030843001259	G3 box; other site
1030843001260	Switch II region; other site
1030843001261	G4 box; other site
1030843001262	G5 box; other site
1030843001263	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1030843001264	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1030843001265	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; cl00922
1030843001266	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1030843001267	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1030843001268	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1030843001269	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1030843001270	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1030843001271	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1030843001272	active site
1030843001273	SAM binding site [chemical binding]; other site
1030843001274	homodimer interface [polypeptide binding]; other site
1030843001275	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1030843001276	active site
1030843001277	putative homodimer interface [polypeptide binding]; other site
1030843001278	SAM binding site [chemical binding]; other site
1030843001279	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1030843001280	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843001281	S-adenosylmethionine binding site [chemical binding]; other site
1030843001282	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1030843001283	active site
1030843001284	SAM binding site [chemical binding]; other site
1030843001285	homodimer interface [polypeptide binding]; other site
1030843001286	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
1030843001287	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1030843001288	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1030843001289	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1030843001290	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1030843001291	DNA binding residues [nucleotide binding]
1030843001292	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
1030843001293	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
1030843001294	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843001295	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843001296	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843001297	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843001298	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
1030843001299	active site
1030843001300	catalytic site [active]
1030843001301	substrate binding site [chemical binding]; other site
1030843001302	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
1030843001303	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1030843001304	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1030843001305	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1030843001306	DNA repair protein RadA; Provisional; Region: PRK11823
1030843001307	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1030843001308	Walker A motif/ATP binding site; other site
1030843001309	ATP binding site [chemical binding]; other site
1030843001310	Walker B motif; other site
1030843001311	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1030843001312	N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism]; Region: COG1834
1030843001313	Amidinotransferase; Region: Amidinotransf; cl12043
1030843001314	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1030843001315	active site
1030843001316	intersubunit interactions; other site
1030843001317	catalytic residue [active]
1030843001318	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
1030843001319	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1030843001320	active site
1030843001321	Zn binding site [ion binding]; other site
1030843001322	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
1030843001323	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1030843001324	FOG: PKD repeat [General function prediction only]; Region: COG3291
1030843001325	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1030843001326	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1030843001327	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843001328	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1030843001329	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1030843001330	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1030843001331	protein binding site [polypeptide binding]; other site
1030843001332	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1030843001333	Catalytic dyad [active]
1030843001334	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1030843001335	ligand binding site [chemical binding]; other site
1030843001336	active site
1030843001337	UGI interface [polypeptide binding]; other site
1030843001338	catalytic site [active]
1030843001339	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
1030843001340	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843001341	motif II; other site
1030843001342	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1030843001343	Predicted methyltransferases [General function prediction only]; Region: COG0313
1030843001344	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1030843001345	putative SAM binding site [chemical binding]; other site
1030843001346	putative homodimer interface [polypeptide binding]; other site
1030843001347	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
1030843001348	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1030843001349	Ligand Binding Site [chemical binding]; other site
1030843001350	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1030843001351	Ligand Binding Site [chemical binding]; other site
1030843001352	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1030843001353	putative rRNA binding site [nucleotide binding]; other site
1030843001354	Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion]; Region: COG5016
1030843001355	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
1030843001356	active site
1030843001357	catalytic residues [active]
1030843001358	metal binding site [ion binding]; metal-binding site
1030843001359	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843001360	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843001361	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843001362	hypothetical protein; Validated; Region: PRK02001
1030843001363	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1030843001364	NusA N-terminal domain; Region: NusA_N; pfam08529
1030843001365	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1030843001366	RNA binding site [nucleotide binding]; other site
1030843001367	homodimer interface [polypeptide binding]; other site
1030843001368	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1030843001369	G-X-X-G motif; other site
1030843001370	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1030843001371	G-X-X-G motif; other site
1030843001372	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1030843001373	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1030843001374	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1030843001375	G1 box; other site
1030843001376	putative GEF interaction site [polypeptide binding]; other site
1030843001377	GTP/Mg2+ binding site [chemical binding]; other site
1030843001378	Switch I region; other site
1030843001379	G2 box; other site
1030843001380	G3 box; other site
1030843001381	Switch II region; other site
1030843001382	G4 box; other site
1030843001383	G5 box; other site
1030843001384	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1030843001385	Translation-initiation factor 2; Region: IF-2; pfam11987
1030843001386	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1030843001387	Colicin V production protein; Region: Colicin_V; pfam02674
1030843001388	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1030843001389	putative ABC transporter; Region: ycf24; CHL00085
1030843001390	FeS assembly ATPase SufC; Region: sufC; TIGR01978
1030843001391	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1030843001392	Walker A/P-loop; other site
1030843001393	ATP binding site [chemical binding]; other site
1030843001394	Q-loop/lid; other site
1030843001395	ABC transporter signature motif; other site
1030843001396	Walker B; other site
1030843001397	D-loop; other site
1030843001398	H-loop/switch region; other site
1030843001399	FeS assembly protein SufD; Region: sufD; TIGR01981
1030843001400	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
1030843001401	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1030843001402	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1030843001403	active site
1030843001404	HIGH motif; other site
1030843001405	dimer interface [polypeptide binding]; other site
1030843001406	KMSKS motif; other site
1030843001407	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1030843001408	RNA binding surface [nucleotide binding]; other site
1030843001409	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1030843001410	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1030843001411	Probable Catalytic site; other site
1030843001412	metal-binding site
1030843001413	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1030843001414	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1030843001415	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1030843001416	active site
1030843001417	HIGH motif; other site
1030843001418	nucleotide binding site [chemical binding]; other site
1030843001419	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1030843001420	KMSK motif region; other site
1030843001421	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1030843001422	tRNA binding surface [nucleotide binding]; other site
1030843001423	anticodon binding site; other site
1030843001424	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1030843001425	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1030843001426	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
1030843001427	putative active site [active]
1030843001428	putative catalytic site [active]
1030843001429	putative DNA binding site [nucleotide binding]; other site
1030843001430	putative phosphate binding site [ion binding]; other site
1030843001431	metal binding site A [ion binding]; metal-binding site
1030843001432	putative AP binding site [nucleotide binding]; other site
1030843001433	putative metal binding site B [ion binding]; other site
1030843001434	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1030843001435	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1030843001436	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1030843001437	dimerization interface [polypeptide binding]; other site
1030843001438	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1030843001439	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1030843001440	dimer interface [polypeptide binding]; other site
1030843001441	ssDNA binding site [nucleotide binding]; other site
1030843001442	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1030843001443	Domain of unknown function DUF21; Region: DUF21; pfam01595
1030843001444	gliding motility-associated protein GldE; Region: GldE; TIGR03520
1030843001445	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1030843001446	Transporter associated domain; Region: CorC_HlyC; smart01091
1030843001447	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1030843001448	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1030843001449	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1030843001450	catalytic residues [active]
1030843001451	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1030843001452	Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK); Region: UMPK_like; cd02028
1030843001453	active site
1030843001454	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1030843001455	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1030843001456	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1030843001457	Aspartase; Region: Aspartase; cd01357
1030843001458	active sites [active]
1030843001459	tetramer interface [polypeptide binding]; other site
1030843001460	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1030843001461	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1030843001462	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
1030843001463	active site
1030843001464	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1030843001465	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1030843001466	nucleotide binding site [chemical binding]; other site
1030843001467	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1030843001468	nudix motif; other site
1030843001469	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1030843001470	Family of unknown function (DUF695); Region: DUF695; pfam05117
1030843001471	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1030843001472	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1030843001473	active site
1030843001474	Int/Topo IB signature motif; other site
1030843001475	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1030843001476	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1030843001477	trimer interface [polypeptide binding]; other site
1030843001478	active site
1030843001479	dimer interface [polypeptide binding]; other site
1030843001480	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1030843001481	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843001482	S-adenosylmethionine binding site [chemical binding]; other site
1030843001483	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1030843001484	dimer interface [polypeptide binding]; other site
1030843001485	catalytic triad [active]
1030843001486	peroxidatic and resolving cysteines [active]
1030843001487	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1030843001488	nucleoside/Zn binding site; other site
1030843001489	dimer interface [polypeptide binding]; other site
1030843001490	catalytic motif [active]
1030843001491	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1030843001492	S1 domain; Region: S1_2; pfam13509
1030843001493	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1030843001494	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
1030843001495	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1030843001496	Competence-damaged protein; Region: CinA; pfam02464
1030843001497	UGMP family protein; Validated; Region: PRK09604
1030843001498	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1030843001499	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1030843001500	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843001501	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843001502	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843001503	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843001504	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843001505	ribonuclease R; Region: RNase_R; TIGR02063
1030843001506	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1030843001507	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1030843001508	RNB domain; Region: RNB; pfam00773
1030843001509	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1030843001510	RNA binding site [nucleotide binding]; other site
1030843001511	GH3 auxin-responsive promoter; Region: GH3; pfam03321
1030843001512	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1030843001513	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1030843001514	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1030843001515	Walker A/P-loop; other site
1030843001516	ATP binding site [chemical binding]; other site
1030843001517	Q-loop/lid; other site
1030843001518	ABC transporter signature motif; other site
1030843001519	Walker B; other site
1030843001520	D-loop; other site
1030843001521	H-loop/switch region; other site
1030843001522	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843001523	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843001524	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
1030843001525	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1030843001526	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1030843001527	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1030843001528	active site residue [active]
1030843001529	alpha-1,2-mannosidase, putative; Region: aman2_put; TIGR01180
1030843001530	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1030843001531	alpha-1,2-mannosidase, putative; Region: aman2_put; TIGR01180
1030843001532	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1030843001533	Septum formation initiator; Region: DivIC; cl17659
1030843001534	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
1030843001535	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1030843001536	RNA binding surface [nucleotide binding]; other site
1030843001537	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1030843001538	active site
1030843001539	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
1030843001540	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1030843001541	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1030843001542	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
1030843001543	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1030843001544	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1030843001545	homodimer interface [polypeptide binding]; other site
1030843001546	metal binding site [ion binding]; metal-binding site
1030843001547	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1030843001548	homodimer interface [polypeptide binding]; other site
1030843001549	active site
1030843001550	putative chemical substrate binding site [chemical binding]; other site
1030843001551	metal binding site [ion binding]; metal-binding site
1030843001552	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1030843001553	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843001554	ATP binding site [chemical binding]; other site
1030843001555	Mg2+ binding site [ion binding]; other site
1030843001556	G-X-G motif; other site
1030843001557	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1030843001558	anchoring element; other site
1030843001559	dimer interface [polypeptide binding]; other site
1030843001560	ATP binding site [chemical binding]; other site
1030843001561	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1030843001562	active site
1030843001563	putative metal-binding site [ion binding]; other site
1030843001564	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1030843001565	Peptidase C26; Region: Peptidase_C26; pfam07722
1030843001566	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1030843001567	catalytic triad [active]
1030843001568	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1030843001569	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1030843001570	active site
1030843001571	dimer interface [polypeptide binding]; other site
1030843001572	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1030843001573	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1030843001574	ATP binding site [chemical binding]; other site
1030843001575	putative Mg++ binding site [ion binding]; other site
1030843001576	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1030843001577	YceG-like family; Region: YceG; pfam02618
1030843001578	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1030843001579	dimerization interface [polypeptide binding]; other site
1030843001580	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1030843001581	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1030843001582	putative ATP binding site [chemical binding]; other site
1030843001583	putative substrate interface [chemical binding]; other site
1030843001584	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1030843001585	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1030843001586	Walker A/P-loop; other site
1030843001587	ATP binding site [chemical binding]; other site
1030843001588	Q-loop/lid; other site
1030843001589	ABC transporter signature motif; other site
1030843001590	Walker B; other site
1030843001591	D-loop; other site
1030843001592	H-loop/switch region; other site
1030843001593	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1030843001594	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1030843001595	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1030843001596	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1030843001597	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1030843001598	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1030843001599	nucleotide binding site/active site [active]
1030843001600	HIT family signature motif; other site
1030843001601	catalytic residue [active]
1030843001602	N-terminal catalytic domain of a thermoactive alpha-amylase from Methanococcus jannaschii and similar proteins; glycoside hydrolase family 57 (GH57); Region: GH57N_MJA1_like; cd10795
1030843001603	Glycosyl hydrolase family 57; Region: Glyco_hydro_57; pfam03065
1030843001604	putative active site [active]
1030843001605	catalytic site [active]
1030843001606	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1030843001607	glycogen synthase, Corynebacterium family; Region: glgA_Coryne; TIGR02149
1030843001608	Glycogen debranching enzyme N terminal; Region: GDE_N; pfam12439
1030843001609	glycogen debranching enzyme, archaeal type, putative; Region: gde_arch; TIGR01561
1030843001610	Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202
1030843001611	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1030843001612	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1030843001613	Walker A/P-loop; other site
1030843001614	ATP binding site [chemical binding]; other site
1030843001615	Q-loop/lid; other site
1030843001616	ABC transporter signature motif; other site
1030843001617	Walker B; other site
1030843001618	D-loop; other site
1030843001619	H-loop/switch region; other site
1030843001620	Phosphoglycerate kinase; Region: PGK; pfam00162
1030843001621	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1030843001622	substrate binding site [chemical binding]; other site
1030843001623	hinge regions; other site
1030843001624	ADP binding site [chemical binding]; other site
1030843001625	catalytic site [active]
1030843001626	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1030843001627	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1030843001628	active site
1030843001629	substrate-binding site [chemical binding]; other site
1030843001630	metal-binding site [ion binding]
1030843001631	ATP binding site [chemical binding]; other site
1030843001632	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1030843001633	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1030843001634	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1030843001635	HlyD family secretion protein; Region: HlyD_3; pfam13437
1030843001636	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1030843001637	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1030843001638	FtsX-like permease family; Region: FtsX; pfam02687
1030843001639	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1030843001640	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1030843001641	FtsX-like permease family; Region: FtsX; pfam02687
1030843001642	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1030843001643	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1030843001644	Walker A/P-loop; other site
1030843001645	ATP binding site [chemical binding]; other site
1030843001646	Q-loop/lid; other site
1030843001647	ABC transporter signature motif; other site
1030843001648	Walker B; other site
1030843001649	D-loop; other site
1030843001650	H-loop/switch region; other site
1030843001651	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
1030843001652	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1030843001653	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1030843001654	DNA binding residues [nucleotide binding]
1030843001655	partial transposase in ISPg5; similar to RefSeq{20100916}, gi|188993976|ref|YP_001928228.1| partial transposase Orf1 in ISPg5 [Porphyromonas gingivalis ATCC 33277]|, percent identity 85 in 60 aa, BLASTP E(): 5e-21
1030843001656	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
1030843001657	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
1030843001658	active site
1030843001659	substrate binding site [chemical binding]; other site
1030843001660	coenzyme B12 binding site [chemical binding]; other site
1030843001661	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1030843001662	B12 binding site [chemical binding]; other site
1030843001663	cobalt ligand [ion binding]; other site
1030843001664	methylmalonyl-CoA mutase, heterodimeric type, beta chain; Region: mmCoA_mut_beta; TIGR00642
1030843001665	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta...; Region: MM_CoA_mutase_beta; cd03677
1030843001666	heterodimer interface [polypeptide binding]; other site
1030843001667	substrate interaction site [chemical binding]; other site
1030843001668	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1030843001669	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843001670	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843001671	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
1030843001672	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843001673	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1030843001674	active site
1030843001675	motif I; other site
1030843001676	motif II; other site
1030843001677	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843001678	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1030843001679	CoenzymeA binding site [chemical binding]; other site
1030843001680	subunit interaction site [polypeptide binding]; other site
1030843001681	PHB binding site; other site
1030843001682	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843001683	binding surface
1030843001684	TPR motif; other site
1030843001685	TPR repeat; Region: TPR_11; pfam13414
1030843001686	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843001687	binding surface
1030843001688	TPR motif; other site
1030843001689	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
1030843001690	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1030843001691	HD domain; Region: HD_4; pfam13328
1030843001692	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1030843001693	synthetase active site [active]
1030843001694	NTP binding site [chemical binding]; other site
1030843001695	metal binding site [ion binding]; metal-binding site
1030843001696	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1030843001697	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1030843001698	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1030843001699	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1030843001700	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1030843001701	putative active site [active]
1030843001702	catalytic site [active]
1030843001703	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1030843001704	putative active site [active]
1030843001705	catalytic site [active]
1030843001706	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843001707	Protein of unknown function (DUF452); Region: DUF452; cl01062
1030843001708	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1030843001709	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1030843001710	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843001711	S-adenosylmethionine binding site [chemical binding]; other site
1030843001712	Interphotoreceptor retinoid-binding protein; serine protease family S41; Region: Peptidase_S41_IRBP; cd07563
1030843001713	active site triad [active]
1030843001714	Protein of unknown function (DUF3316); Region: DUF3316; pfam11777
1030843001715	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
1030843001716	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
1030843001717	CAP-like domain; other site
1030843001718	active site
1030843001719	primary dimer interface [polypeptide binding]; other site
1030843001720	FMN-binding domain; Region: FMN_bind; pfam04205
1030843001721	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1030843001722	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1030843001723	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1030843001724	partial transposase in ISPg4; similar to nr, gi|188994342|ref|YP_001928594.1| partial transposase in ISPg4 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg4 [Porphyromonas gingivalis ATCC 33277], percent identity 92.9 in 56 aa, BLASTP E(): 7e-24
1030843001725	partial transposase in ISPg4; similar to RefSeq{20100916}, gi|188994344|ref|YP_001928596.1| partial transposase in ISPg4 [Porphyromonas gingivalis ATCC 33277]|, percent identity 93.5 in 62 aa, BLASTP E(): 1e-27
1030843001726	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1030843001727	active site
1030843001728	catalytic residues [active]
1030843001729	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1030843001730	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
1030843001731	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1030843001732	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1030843001733	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1030843001734	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1030843001735	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1030843001736	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
1030843001737	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1030843001738	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1030843001739	catalytic residues [active]
1030843001740	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1030843001741	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1030843001742	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1030843001743	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1030843001744	active site
1030843001745	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1030843001746	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1030843001747	metal-binding site [ion binding]
1030843001748	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1030843001749	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843001750	motif II; other site
1030843001751	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1030843001752	metal-binding site [ion binding]
1030843001753	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
1030843001754	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
1030843001755	proximal heme binding site [chemical binding]; other site
1030843001756	distal heme binding site [chemical binding]; other site
1030843001757	putative dimer interface [polypeptide binding]; other site
1030843001758	putative Iron-sulfur protein interface [polypeptide binding]; other site
1030843001759	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
1030843001760	L-aspartate oxidase; Provisional; Region: PRK06175
1030843001761	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1030843001762	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
1030843001763	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1030843001764	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1030843001765	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
1030843001766	dimer interface [polypeptide binding]; other site
1030843001767	substrate binding site [chemical binding]; other site
1030843001768	metal binding site [ion binding]; metal-binding site
1030843001769	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
1030843001770	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1030843001771	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1030843001772	Lamin Tail Domain; Region: LTD; pfam00932
1030843001773	putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK05641
1030843001774	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1030843001775	carboxyltransferase (CT) interaction site; other site
1030843001776	biotinylation site [posttranslational modification]; other site
1030843001777	Na+-transporting oxaloacetate decarboxylase beta subunit; Region: OAD_beta; cl00816
1030843001778	partial transposase in ISPg1; similar to nr, gi|188994872|ref|YP_001929124.1| partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277], percent identity 100 in 48 aa, BLASTP E(): 5e-20
1030843001779	Domain of unknown function (DUF4372); Region: DUF4372; pfam14294
1030843001780	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1030843001781	Zn2+ binding site [ion binding]; other site
1030843001782	Mg2+ binding site [ion binding]; other site
1030843001783	Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; Region: Peptidase_C1B; cd00585
1030843001784	trimer interface [polypeptide binding]; other site
1030843001785	active site
1030843001786	G bulge; other site
1030843001787	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1030843001788	active site
1030843001789	dimerization interface [polypeptide binding]; other site
1030843001790	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1030843001791	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1030843001792	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1030843001793	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1030843001794	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1030843001795	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
1030843001796	lipoprotein signal peptidase; Provisional; Region: PRK14788
1030843001797	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1030843001798	isoleucyl-tRNA synthetase; Region: ileS; TIGR00392
1030843001799	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1030843001800	HIGH motif; other site
1030843001801	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1030843001802	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1030843001803	active site
1030843001804	KMSKS motif; other site
1030843001805	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1030843001806	tRNA binding surface [nucleotide binding]; other site
1030843001807	anticodon binding site; other site
1030843001808	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1030843001809	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1030843001810	substrate binding site [chemical binding]; other site
1030843001811	hexamer interface [polypeptide binding]; other site
1030843001812	metal binding site [ion binding]; metal-binding site
1030843001813	Competence protein; Region: Competence; pfam03772
1030843001814	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1030843001815	Shikimate kinase; Region: SKI; pfam01202
1030843001816	ADP binding site [chemical binding]; other site
1030843001817	magnesium binding site [ion binding]; other site
1030843001818	putative shikimate binding site; other site
1030843001819	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
1030843001820	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1030843001821	Zn2+ binding site [ion binding]; other site
1030843001822	Mg2+ binding site [ion binding]; other site
1030843001823	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1030843001824	dihydropteroate synthase; Region: DHPS; TIGR01496
1030843001825	substrate binding pocket [chemical binding]; other site
1030843001826	dimer interface [polypeptide binding]; other site
1030843001827	inhibitor binding site; inhibition site
1030843001828	Uncharacterized conserved protein [Function unknown]; Region: COG1624
1030843001829	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1030843001830	PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_4; cd03395
1030843001831	active site
1030843001832	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1030843001833	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843001834	TPR motif; other site
1030843001835	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1030843001836	Oxygen tolerance; Region: BatD; pfam13584
1030843001837	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1030843001838	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843001839	TPR motif; other site
1030843001840	binding surface
1030843001841	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
1030843001842	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1030843001843	metal ion-dependent adhesion site (MIDAS); other site
1030843001844	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
1030843001845	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
1030843001846	metal ion-dependent adhesion site (MIDAS); other site
1030843001847	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1030843001848	Protein of unknown function DUF58; Region: DUF58; pfam01882
1030843001849	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1030843001850	metal ion-dependent adhesion site (MIDAS); other site
1030843001851	MoxR-like ATPases [General function prediction only]; Region: COG0714
1030843001852	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843001853	Walker A motif; other site
1030843001854	ATP binding site [chemical binding]; other site
1030843001855	Walker B motif; other site
1030843001856	arginine finger; other site
1030843001857	Quinolinate synthetase A protein; Region: NadA; pfam02445
1030843001858	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1030843001859	nicotinate-nucleotide pyrophosphorylase; Region: nadC; TIGR00078
1030843001860	dimerization interface [polypeptide binding]; other site
1030843001861	active site
1030843001862	L-aspartate oxidase; Provisional; Region: PRK06175
1030843001863	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
1030843001864	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1030843001865	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1030843001866	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1030843001867	ligand binding site [chemical binding]; other site
1030843001868	flexible hinge region; other site
1030843001869	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1030843001870	non-specific DNA interactions [nucleotide binding]; other site
1030843001871	DNA binding site [nucleotide binding]
1030843001872	sequence specific DNA binding site [nucleotide binding]; other site
1030843001873	putative cAMP binding site [chemical binding]; other site
1030843001874	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1030843001875	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1030843001876	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1030843001877	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1030843001878	active site residue [active]
1030843001879	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1030843001880	active site residue [active]
1030843001881	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843001882	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843001883	partial transposase in ISPg2; similar to RefSeq{20100916}, gi|188994406|ref|YP_001928658.1| partial transposase in ISPg2 [Porphyromonas gingivalis ATCC 33277]|, percent identity 95.4 in 65 aa, BLASTP E(): 6e-28
1030843001884	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1030843001885	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1030843001886	HIGH motif; other site
1030843001887	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1030843001888	active site
1030843001889	KMSKS motif; other site
1030843001890	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
1030843001891	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1030843001892	Sulfatase; Region: Sulfatase; cl17466
1030843001893	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1030843001894	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1030843001895	substrate binding site; other site
1030843001896	tetramer interface; other site
1030843001897	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
1030843001898	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1030843001899	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
1030843001900	NADP binding site [chemical binding]; other site
1030843001901	active site
1030843001902	putative substrate binding site [chemical binding]; other site
1030843001903	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1030843001904	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1030843001905	NAD binding site [chemical binding]; other site
1030843001906	substrate binding site [chemical binding]; other site
1030843001907	homodimer interface [polypeptide binding]; other site
1030843001908	active site
1030843001909	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1030843001910	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1030843001911	Uncharacterized conserved protein (DUF2149); Region: DUF2149; pfam09919
1030843001912	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1030843001913	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
1030843001914	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
1030843001915	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
1030843001916	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
1030843001917	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
1030843001918	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1030843001919	N-terminal plug; other site
1030843001920	ligand-binding site [chemical binding]; other site
1030843001921	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
1030843001922	Peptidase C10 family; Region: Peptidase_C10; pfam01640
1030843001923	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843001924	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1030843001925	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1030843001926	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1030843001927	hypothetical protein; Validated; Region: PRK02101
1030843001928	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1030843001929	active site
1030843001930	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1030843001931	Peptidase family U32; Region: Peptidase_U32; pfam01136
1030843001932	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1030843001933	catalytic center binding site [active]
1030843001934	ATP binding site [chemical binding]; other site
1030843001935	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1030843001936	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1030843001937	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1030843001938	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
1030843001939	RNA binding site [nucleotide binding]; other site
1030843001940	active site
1030843001941	Bacitracin resistance protein BacA; Region: BacA; pfam02673
1030843001942	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
1030843001943	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1030843001944	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1030843001945	non-specific DNA binding site [nucleotide binding]; other site
1030843001946	salt bridge; other site
1030843001947	sequence-specific DNA binding site [nucleotide binding]; other site
1030843001948	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843001949	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1030843001950	active site
1030843001951	metal binding site [ion binding]; metal-binding site
1030843001952	interdomain interaction site; other site
1030843001953	AAA domain; Region: AAA_25; pfam13481
1030843001954	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1030843001955	Walker A motif; other site
1030843001956	ATP binding site [chemical binding]; other site
1030843001957	Walker B motif; other site
1030843001958	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1030843001959	DNA binding residues [nucleotide binding]
1030843001960	potential frameshift: common BLAST hit: gi|29349845|ref|NP_813348.1| transposase
1030843001961	partial transposase in ISPg10; similar to RefSeq{20100916}, gi|254883144|ref|ZP_05255854.1| transposase [Bacteroides sp. 4_3_47FAA]|, percent identity 77 in 74 aa, BLASTP E(): 1e-28
1030843001962	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1030843001963	partial transposase in ISPg10; similar to RefSeq{20100916}, gi|254883144|ref|ZP_05255854.1| transposase [Bacteroides sp. 4_3_47FAA]|, percent identity 82.4 in 102 aa, BLASTP E(): 4e-42
1030843001964	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1030843001965	synthetase active site [active]
1030843001966	NTP binding site [chemical binding]; other site
1030843001967	metal binding site [ion binding]; metal-binding site
1030843001968	NACHT domain; Region: NACHT; pfam05729
1030843001969	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1030843001970	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1030843001971	AAA domain; Region: AAA_14; pfam13173
1030843001972	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1030843001973	DNA binding residues [nucleotide binding]
1030843001974	Divergent AAA domain; Region: AAA_4; pfam04326
1030843001975	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1030843001976	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1030843001977	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Region: menD; TIGR00173
1030843001978	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1030843001979	dimer interface [polypeptide binding]; other site
1030843001980	tetramer interface [polypeptide binding]; other site
1030843001981	PYR/PP interface [polypeptide binding]; other site
1030843001982	TPP binding site [chemical binding]; other site
1030843001983	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1030843001984	TPP-binding site; other site
1030843001985	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1030843001986	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1030843001987	substrate binding site [chemical binding]; other site
1030843001988	oxyanion hole (OAH) forming residues; other site
1030843001989	trimer interface [polypeptide binding]; other site
1030843001990	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1030843001991	o-succinylbenzoate synthase; Region: menC_gamma/gm+; TIGR01927
1030843001992	active site
1030843001993	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1030843001994	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1030843001995	AMP binding site [chemical binding]; other site
1030843001996	active site
1030843001997	acyl-activating enzyme (AAE) consensus motif; other site
1030843001998	CoA binding site [chemical binding]; other site
1030843001999	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1030843002000	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1030843002001	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1030843002002	active site
1030843002003	Int/Topo IB signature motif; other site
1030843002004	DNA binding site [nucleotide binding]
1030843002005	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
1030843002006	RteC protein; Region: RteC; pfam09357
1030843002007	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1030843002008	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1030843002009	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1030843002010	Helix-turn-helix domain; Region: HTH_18; pfam12833
1030843002011	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1030843002012	Protein of unknown function with HXXEE motif; Region: HXXEE; pfam13787
1030843002013	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843002014	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
1030843002015	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1030843002016	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843002017	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843002018	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843002019	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1030843002020	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1030843002021	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1030843002022	G1 box; other site
1030843002023	GTP/Mg2+ binding site [chemical binding]; other site
1030843002024	Switch I region; other site
1030843002025	G2 box; other site
1030843002026	Switch II region; other site
1030843002027	G3 box; other site
1030843002028	G4 box; other site
1030843002029	G5 box; other site
1030843002030	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1030843002031	gliding motility-associated lipoprotein GldB; Region: GldB_lipo; TIGR03514
1030843002032	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843002033	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843002034	Homologues of TraJ from Bacteroides conjugative transposon; Region: CtnDOT_TraJ; pfam07863
1030843002035	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1030843002036	catalytic triad [active]
1030843002037	recombinase A; Provisional; Region: recA; PRK09354
1030843002038	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1030843002039	hexamer interface [polypeptide binding]; other site
1030843002040	Walker A motif; other site
1030843002041	ATP binding site [chemical binding]; other site
1030843002042	Walker B motif; other site
1030843002043	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1030843002044	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u7; cd10931
1030843002045	putative active site [active]
1030843002046	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1030843002047	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1030843002048	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
1030843002049	Chorismate mutase type II; Region: CM_2; smart00830
1030843002050	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cl00233
1030843002051	catalytic center binding site [active]
1030843002052	ATP binding site [chemical binding]; other site
1030843002053	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; cl09920
1030843002054	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1030843002055	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1030843002056	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1030843002057	active site
1030843002058	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
1030843002059	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
1030843002060	active site
1030843002061	dimer interface [polypeptide binding]; other site
1030843002062	hybrid cluster protein; Provisional; Region: PRK05290
1030843002063	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1030843002064	ACS interaction site; other site
1030843002065	CODH interaction site; other site
1030843002066	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1030843002067	hybrid metal cluster; other site
1030843002068	hypothetical protein; Reviewed; Region: PRK00024
1030843002069	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1030843002070	MPN+ (JAMM) motif; other site
1030843002071	Zinc-binding site [ion binding]; other site
1030843002072	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1030843002073	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1030843002074	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1030843002075	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1030843002076	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1030843002077	Alpha amylase catalytic domain found in an uncharacterized protein family; Region: AmyAc_3; cd11349
1030843002078	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1030843002079	active site
1030843002080	catalytic site [active]
1030843002081	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1030843002082	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
1030843002083	active site
1030843002084	nucleophile elbow; other site
1030843002085	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1030843002086	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1030843002087	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1030843002088	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1030843002089	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1030843002090	alpha-1,2-mannosidase, putative; Region: aman2_put; TIGR01180
1030843002091	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1030843002092	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); Region: PvlArgDC; cl00849
1030843002093	NlpE N-terminal domain; Region: NlpE; pfam04170
1030843002094	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
1030843002095	putative active site [active]
1030843002096	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1030843002097	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1030843002098	phosphopeptide binding site; other site
1030843002099	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1030843002100	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843002101	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843002102	potential protein location (hypothetical protein PGTDC60_0840 [Porphyromonas gingivalis TDC60]) that overlaps RNA (tRNA-A)
1030843002103	Predicted membrane protein [Function unknown]; Region: COG2246
1030843002104	GtrA-like protein; Region: GtrA; pfam04138
1030843002105	dihydroorotase; Reviewed; Region: PRK09236
1030843002106	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1030843002107	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
1030843002108	active site
1030843002109	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
1030843002110	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
1030843002111	Ligand binding site; other site
1030843002112	Putative Catalytic site; other site
1030843002113	DXD motif; other site
1030843002114	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1030843002115	FtsX-like permease family; Region: FtsX; pfam02687
1030843002116	Ribosome-binding factor A; Region: RBFA; pfam02033
1030843002117	5'-nucleotidase, lipoprotein e(P4) family; Region: lipo_e_P4; TIGR01533
1030843002118	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
1030843002119	thymidine kinase; Provisional; Region: PRK04296
1030843002120	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1030843002121	Response regulator receiver domain; Region: Response_reg; pfam00072
1030843002122	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1030843002123	active site
1030843002124	phosphorylation site [posttranslational modification]
1030843002125	intermolecular recognition site; other site
1030843002126	dimerization interface [polypeptide binding]; other site
1030843002127	PglZ domain; Region: PglZ; pfam08665
1030843002128	AAA domain; Region: AAA_14; pfam13173
1030843002129	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1030843002130	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843002131	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
1030843002132	Predicted metal-binding protein (DUF2103); Region: DUF2103; cl01651
1030843002133	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1030843002134	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
1030843002135	elongation factor G; Reviewed; Region: PRK12740
1030843002136	G1 box; other site
1030843002137	putative GEF interaction site [polypeptide binding]; other site
1030843002138	GTP/Mg2+ binding site [chemical binding]; other site
1030843002139	Switch I region; other site
1030843002140	G2 box; other site
1030843002141	G3 box; other site
1030843002142	Switch II region; other site
1030843002143	G4 box; other site
1030843002144	G5 box; other site
1030843002145	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1030843002146	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1030843002147	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1030843002148	hypothetical protein; Provisional; Region: PRK00955
1030843002149	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1030843002150	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1030843002151	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14609
1030843002152	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1030843002153	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1030843002154	LytTr DNA-binding domain; Region: LytTR; cl04498
1030843002155	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1030843002156	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1030843002157	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1030843002158	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1030843002159	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843002160	motif II; other site
1030843002161	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1030843002162	partial transposase in ISPg1; similar to RefSeq{20100916}, gi|188994872|ref|YP_001929124.1| partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277]|, percent identity 96.9 in 192 aa, BLASTP E(): 1e-106
1030843002163	partial transposase in ISPg3; similar to nr, gi|188993971|ref|YP_001928223.1| partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277], percent identity 95.8 in 24 aa, BLASTP E(): 9e-6
1030843002164	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843002165	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843002166	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843002167	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1030843002168	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1030843002169	ATP-binding cassette domain of an uncharacterized transporter; Region: ABC_putative_ATPase; cd03269
1030843002170	Walker A/P-loop; other site
1030843002171	ATP binding site [chemical binding]; other site
1030843002172	Q-loop/lid; other site
1030843002173	ABC transporter signature motif; other site
1030843002174	Walker B; other site
1030843002175	D-loop; other site
1030843002176	H-loop/switch region; other site
1030843002177	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1030843002178	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
1030843002179	AMP nucleosidase; Provisional; Region: PRK07115
1030843002180	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1030843002181	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1030843002182	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1030843002183	lipoyl attachment site [posttranslational modification]; other site
1030843002184	AIR carboxylase; Region: AIRC; pfam00731
1030843002185	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional; Region: PRK02048
1030843002186	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1030843002187	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1030843002188	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1030843002189	trimer interface [polypeptide binding]; other site
1030843002190	active site
1030843002191	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002192	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843002193	binding surface
1030843002194	TPR motif; other site
1030843002195	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1030843002196	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002197	TPR motif; other site
1030843002198	binding surface
1030843002199	TPR repeat; Region: TPR_11; pfam13414
1030843002200	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002201	binding surface
1030843002202	TPR motif; other site
1030843002203	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
1030843002204	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
1030843002205	Peptidase family M23; Region: Peptidase_M23; pfam01551
1030843002206	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1030843002207	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1030843002208	active site
1030843002209	Riboflavin kinase; Region: Flavokinase; pfam01687
1030843002210	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1030843002211	Domain of unknown function DUF59; Region: DUF59; pfam01883
1030843002212	cell division ATPase MinD, archaeal; Region: minD_arch; TIGR01969
1030843002213	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1030843002214	Walker A motif; other site
1030843002215	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843002216	S-adenosylmethionine binding site [chemical binding]; other site
1030843002217	prolyl-tRNA synthetase; Provisional; Region: PRK08661
1030843002218	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
1030843002219	dimer interface [polypeptide binding]; other site
1030843002220	motif 1; other site
1030843002221	active site
1030843002222	motif 2; other site
1030843002223	motif 3; other site
1030843002224	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
1030843002225	anticodon binding site; other site
1030843002226	zinc-binding site [ion binding]; other site
1030843002227	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1030843002228	CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473
1030843002229	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
1030843002230	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
1030843002231	Mrr N-terminal domain; Region: Mrr_N; pfam14338
1030843002232	Restriction endonuclease; Region: Mrr_cat; pfam04471
1030843002233	Queuosine biosynthesis protein; Region: Queuosine_synth; cl00523
1030843002234	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1030843002235	alpha-1,2-mannosidase, putative; Region: aman2_put; TIGR01180
1030843002236	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1030843002237	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1030843002238	PhoH-like protein; Region: PhoH; pfam02562
1030843002239	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
1030843002240	ATP binding site [chemical binding]; other site
1030843002241	active site
1030843002242	substrate binding site [chemical binding]; other site
1030843002243	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1030843002244	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843002245	S-adenosylmethionine binding site [chemical binding]; other site
1030843002246	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
1030843002247	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1030843002248	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1030843002249	shikimate binding site; other site
1030843002250	NAD(P) binding site [chemical binding]; other site
1030843002251	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1030843002252	Surface antigen; Region: Bac_surface_Ag; pfam01103
1030843002253	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1030843002254	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1030843002255	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1030843002256	DNA binding residues [nucleotide binding]
1030843002257	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
1030843002258	partial transposase in ISPg1; similar to RefSeq{20100916}, gi|188994831|ref|YP_001929083.1| partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277]|, percent identity 95 in 141 aa, BLASTP E(): 8e-74
1030843002259	partial transposase in ISPg1; similar to RefSeq{20100916}, gi|188994830|ref|YP_001929082.1| partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277]|, percent identity 98.2 in 166 aa, BLASTP E(): 5e-91
1030843002260	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1030843002261	23S rRNA binding site [nucleotide binding]; other site
1030843002262	L21 binding site [polypeptide binding]; other site
1030843002263	L13 binding site [polypeptide binding]; other site
1030843002264	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1030843002265	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1030843002266	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1030843002267	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1030843002268	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1030843002269	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1030843002270	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1030843002271	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1030843002272	active site
1030843002273	dimer interface [polypeptide binding]; other site
1030843002274	motif 1; other site
1030843002275	motif 2; other site
1030843002276	motif 3; other site
1030843002277	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1030843002278	anticodon binding site; other site
1030843002279	partial transposase in ISPg2; similar to nr, gi|34540119|ref|NP_904598.1| ISPg2, transposase [Porphyromonas gingivalis W83] ISPg2, transposase [Porphyromonas gingivalis W83] ISPg2, transposase [Porphyromonas gingivalis W83] ISPg2, transposase [Porphyromonas gingivalis W83] ISPg2, transposase [Porphyromonas gingivalis W83] putative transposase [Porphyromonas gingivalis] ISPg2, transposase [Porphyromonas gingivalis W83] ISPg2, transposase [Porphyromonas gingivalis W83] ISPg2, transposase [Porphyromonas gingivalis W83] ISPg2, transposase [Porphyromonas gingivalis W83] ISPg2, transposase [Porphyromonas gingivalis W83], percent identity 44.3 in 61 aa, BLASTP E(): 9e-6
1030843002280	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1030843002281	TIGR01777 family protein; Region: yfcH
1030843002282	putative NAD(P) binding site [chemical binding]; other site
1030843002283	putative active site [active]
1030843002284	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843002285	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843002286	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843002287	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1030843002288	non-specific DNA binding site [nucleotide binding]; other site
1030843002289	salt bridge; other site
1030843002290	sequence-specific DNA binding site [nucleotide binding]; other site
1030843002291	Protein of unknown function with HXXEE motif; Region: HXXEE; pfam13787
1030843002292	A new structural DNA glycosylase; Region: AlkD_like; cl11434
1030843002293	active site
1030843002294	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
1030843002295	hypothetical protein; Provisional; Region: PRK14851
1030843002296	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1030843002297	dimer interface [polypeptide binding]; other site
1030843002298	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1030843002299	dimer interface [polypeptide binding]; other site
1030843002300	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1030843002301	Domain of unknown function (DUF4403); Region: DUF4403; pfam14356
1030843002302	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1030843002303	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1030843002304	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843002305	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1030843002306	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843002307	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1030843002308	DNA-binding site [nucleotide binding]; DNA binding site
1030843002309	envelope glycoprotein E; Provisional; Region: PHA03283
1030843002310	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1030843002311	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843002312	Walker A/P-loop; other site
1030843002313	ATP binding site [chemical binding]; other site
1030843002314	Q-loop/lid; other site
1030843002315	ABC transporter signature motif; other site
1030843002316	Walker B; other site
1030843002317	D-loop; other site
1030843002318	H-loop/switch region; other site
1030843002319	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
1030843002320	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1030843002321	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843002322	FeS/SAM binding site; other site
1030843002323	TRAM domain; Region: TRAM; pfam01938
1030843002324	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
1030843002325	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1030843002326	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1030843002327	SIR2-like domain; Region: SIR2_2; pfam13289
1030843002328	TPR repeat; Region: TPR_11; pfam13414
1030843002329	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002330	TPR motif; other site
1030843002331	binding surface
1030843002332	TPR repeat; Region: TPR_11; pfam13414
1030843002333	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002334	binding surface
1030843002335	TPR motif; other site
1030843002336	TPR repeat; Region: TPR_11; pfam13414
1030843002337	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002338	TPR motif; other site
1030843002339	pyruvate phosphate dikinase; Provisional; Region: PRK09279
1030843002340	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1030843002341	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1030843002342	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1030843002343	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843002344	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1030843002345	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1030843002346	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1030843002347	substrate-cofactor binding pocket; other site
1030843002348	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843002349	catalytic residue [active]
1030843002350	para-aminobenzoate synthase component I; Validated; Region: PRK07093
1030843002351	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1030843002352	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1030843002353	Walker A/P-loop; other site
1030843002354	ATP binding site [chemical binding]; other site
1030843002355	Q-loop/lid; other site
1030843002356	ABC transporter signature motif; other site
1030843002357	Walker B; other site
1030843002358	D-loop; other site
1030843002359	H-loop/switch region; other site
1030843002360	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1030843002361	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843002362	Walker A/P-loop; other site
1030843002363	ATP binding site [chemical binding]; other site
1030843002364	Q-loop/lid; other site
1030843002365	ABC transporter signature motif; other site
1030843002366	Walker B; other site
1030843002367	D-loop; other site
1030843002368	H-loop/switch region; other site
1030843002369	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1030843002370	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1030843002371	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1030843002372	TM-ABC transporter signature motif; other site
1030843002373	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1030843002374	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1030843002375	TM-ABC transporter signature motif; other site
1030843002376	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002377	binding surface
1030843002378	TPR motif; other site
1030843002379	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843002380	Permease; Region: Permease; pfam02405
1030843002381	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1030843002382	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1030843002383	Walker A/P-loop; other site
1030843002384	ATP binding site [chemical binding]; other site
1030843002385	Q-loop/lid; other site
1030843002386	ABC transporter signature motif; other site
1030843002387	Walker B; other site
1030843002388	D-loop; other site
1030843002389	H-loop/switch region; other site
1030843002390	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1030843002391	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1030843002392	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1030843002393	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1030843002394	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1030843002395	SWIM zinc finger; Region: SWIM; pfam04434
1030843002396	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1030843002397	Part of AAA domain; Region: AAA_19; pfam13245
1030843002398	Family description; Region: UvrD_C_2; pfam13538
1030843002399	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1030843002400	Sulfatase; Region: Sulfatase; cl17466
1030843002401	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1030843002402	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
1030843002403	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1030843002404	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1030843002405	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1030843002406	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1030843002407	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1030843002408	G1 box; other site
1030843002409	GTP/Mg2+ binding site [chemical binding]; other site
1030843002410	Switch I region; other site
1030843002411	G2 box; other site
1030843002412	G3 box; other site
1030843002413	Switch II region; other site
1030843002414	G4 box; other site
1030843002415	G5 box; other site
1030843002416	Nucleoside recognition; Region: Gate; pfam07670
1030843002417	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1030843002418	Nucleoside recognition; Region: Gate; pfam07670
1030843002419	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
1030843002420	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1030843002421	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1030843002422	This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; Region: FeoA; smart00899
1030843002423	FeoA domain; Region: FeoA; pfam04023
1030843002424	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1030843002425	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1030843002426	active site
1030843002427	metal binding site [ion binding]; metal-binding site
1030843002428	Sporulation related domain; Region: SPOR; cl10051
1030843002429	virulence factor Mce family protein; Region: Mtu_fam_mce; TIGR00996
1030843002430	mce related protein; Region: MCE; pfam02470
1030843002431	O-Antigen ligase; Region: Wzy_C; pfam04932
1030843002432	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
1030843002433	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1030843002434	DNA binding residues [nucleotide binding]
1030843002435	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1030843002436	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1030843002437	ligand binding site [chemical binding]; other site
1030843002438	flexible hinge region; other site
1030843002439	helix_turn_helix, cAMP Regulatory protein; Region: HTH_CRP; smart00419
1030843002440	Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; Region: CysPc; cl00051
1030843002441	catalytic site [active]
1030843002442	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1030843002443	active site
1030843002444	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1030843002445	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843002446	FeS/SAM binding site; other site
1030843002447	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1030843002448	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1030843002449	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1030843002450	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1030843002451	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1030843002452	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1030843002453	ligand binding site [chemical binding]; other site
1030843002454	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1030843002455	CoenzymeA binding site [chemical binding]; other site
1030843002456	subunit interaction site [polypeptide binding]; other site
1030843002457	PHB binding site; other site
1030843002458	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1030843002459	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
1030843002460	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1030843002461	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1030843002462	Cysteine-rich domain; Region: CCG; pfam02754
1030843002463	Cysteine-rich domain; Region: CCG; pfam02754
1030843002464	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
1030843002465	Int/Topo IB signature motif; other site
1030843002466	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
1030843002467	putative DNA binding site [nucleotide binding]; other site
1030843002468	putative Zn2+ binding site [ion binding]; other site
1030843002469	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1030843002470	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843002471	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843002472	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843002473	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843002474	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1030843002475	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
1030843002476	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1030843002477	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
1030843002478	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
1030843002479	nucleotide binding region [chemical binding]; other site
1030843002480	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1030843002481	ATP-binding site [chemical binding]; other site
1030843002482	Domain of unknown function (DUF1896); Region: DUF1896; pfam08989
1030843002483	DNA topoisomerase III; Provisional; Region: PRK07726
1030843002484	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1030843002485	active site
1030843002486	putative interdomain interaction site [polypeptide binding]; other site
1030843002487	putative metal-binding site [ion binding]; other site
1030843002488	putative nucleotide binding site [chemical binding]; other site
1030843002489	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1030843002490	domain I; other site
1030843002491	DNA binding groove [nucleotide binding]
1030843002492	phosphate binding site [ion binding]; other site
1030843002493	domain II; other site
1030843002494	domain III; other site
1030843002495	nucleotide binding site [chemical binding]; other site
1030843002496	catalytic site [active]
1030843002497	domain IV; other site
1030843002498	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
1030843002499	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
1030843002500	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
1030843002501	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
1030843002502	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1030843002503	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1030843002504	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK06816
1030843002505	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
1030843002506	dimer interface [polypeptide binding]; other site
1030843002507	active site
1030843002508	radical SAM/SPASM domain Clo7bot peptide maturase; Region: rSAM_Clo7bot; TIGR04334
1030843002509	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843002510	FeS/SAM binding site; other site
1030843002511	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843002512	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843002513	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1030843002514	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1030843002515	putative active site [active]
1030843002516	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1030843002517	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843002518	Walker A/P-loop; other site
1030843002519	ATP binding site [chemical binding]; other site
1030843002520	Q-loop/lid; other site
1030843002521	ABC transporter signature motif; other site
1030843002522	Walker B; other site
1030843002523	D-loop; other site
1030843002524	H-loop/switch region; other site
1030843002525	RteC protein; Region: RteC; pfam09357
1030843002526	YWFCY protein; Region: YWFCY; pfam14293
1030843002527	AAA-like domain; Region: AAA_10; pfam12846
1030843002528	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1030843002529	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
1030843002530	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1030843002531	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1030843002532	P-loop; other site
1030843002533	Magnesium ion binding site [ion binding]; other site
1030843002534	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
1030843002535	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
1030843002536	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1030843002537	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1030843002538	P-loop; other site
1030843002539	Magnesium ion binding site [ion binding]; other site
1030843002540	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
1030843002541	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
1030843002542	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
1030843002543	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
1030843002544	Domain of unknown function (DUF4141); Region: DUF4141; pfam13605
1030843002545	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
1030843002546	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
1030843002547	Protein of unknown function (DUF3989); Region: DUF3989; pfam13150
1030843002548	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
1030843002549	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
1030843002550	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
1030843002551	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
1030843002552	Conjugative transposon protein TraO; Region: TraO; pfam10626
1030843002553	CHC2 zinc finger; Region: zf-CHC2; cl17510
1030843002554	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1030843002555	active site
1030843002556	metal binding site [ion binding]; metal-binding site
1030843002557	interdomain interaction site; other site
1030843002558	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
1030843002559	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1030843002560	PcfJ-like protein; Region: PcfJ; pfam14284
1030843002561	Antirestriction protein (ArdA); Region: ArdA; cl01953
1030843002562	PcfK-like protein; Region: PcfK; pfam14058
1030843002563	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1030843002564	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1030843002565	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843002566	motif II; other site
1030843002567	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1030843002568	active site
1030843002569	dimerization interface [polypeptide binding]; other site
1030843002570	Archaeal adenylate kinase [Nucleotide transport and metabolism]; Region: AdkA; cl17890
1030843002571	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1030843002572	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
1030843002573	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1030843002574	active site
1030843002575	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1030843002576	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1030843002577	catalytic triad [active]
1030843002578	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
1030843002579	cobyric acid synthase; Provisional; Region: PRK00784
1030843002580	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1030843002581	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1030843002582	catalytic triad [active]
1030843002583	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
1030843002584	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1030843002585	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843002586	homodimer interface [polypeptide binding]; other site
1030843002587	catalytic residue [active]
1030843002588	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
1030843002589	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1030843002590	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
1030843002591	putative ADP-binding pocket [chemical binding]; other site
1030843002592	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1030843002593	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1030843002594	dimer interface [polypeptide binding]; other site
1030843002595	active site
1030843002596	metal binding site [ion binding]; metal-binding site
1030843002597	Protein of unknown function (DUF4254); Region: DUF4254; pfam14063
1030843002598	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1030843002599	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1030843002600	putative active site [active]
1030843002601	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1030843002602	RNA binding surface [nucleotide binding]; other site
1030843002603	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1030843002604	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1030843002605	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1030843002606	acyl-activating enzyme (AAE) consensus motif; other site
1030843002607	putative AMP binding site [chemical binding]; other site
1030843002608	putative active site [active]
1030843002609	putative CoA binding site [chemical binding]; other site
1030843002610	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1030843002611	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1030843002612	RF-1 domain; Region: RF-1; pfam00472
1030843002613	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1030843002614	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1030843002615	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1030843002616	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1030843002617	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1030843002618	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1030843002619	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1030843002620	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1030843002621	Probable Catalytic site; other site
1030843002622	metal-binding site
1030843002623	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
1030843002624	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1030843002625	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1030843002626	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1030843002627	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1030843002628	inhibitor-cofactor binding pocket; inhibition site
1030843002629	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843002630	catalytic residue [active]
1030843002631	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1030843002632	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1030843002633	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
1030843002634	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1030843002635	Ligand Binding Site [chemical binding]; other site
1030843002636	Molecular Tunnel; other site
1030843002637	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1030843002638	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1030843002639	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1030843002640	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1030843002641	potential protein location (hypothetical protein PGTDC60_1080 [Porphyromonas gingivalis TDC60]) that overlaps RNA (tRNA-T)
1030843002642	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1030843002643	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1030843002644	HIGH motif; other site
1030843002645	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1030843002646	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1030843002647	active site
1030843002648	KMSKS motif; other site
1030843002649	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1030843002650	tRNA binding surface [nucleotide binding]; other site
1030843002651	anticodon binding site; other site
1030843002652	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1030843002653	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843002654	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843002655	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002656	TPR motif; other site
1030843002657	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843002658	binding surface
1030843002659	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
1030843002660	ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Region: NrdJ_Z; TIGR02504
1030843002661	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
1030843002662	active site
1030843002663	dimer interface [polypeptide binding]; other site
1030843002664	effector binding site; other site
1030843002665	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1030843002666	TSCPD domain; Region: TSCPD; cl14834
1030843002667	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1030843002668	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1030843002669	generic binding surface II; other site
1030843002670	generic binding surface I; other site
1030843002671	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1030843002672	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1030843002673	putative DNA binding site [nucleotide binding]; other site
1030843002674	putative Zn2+ binding site [ion binding]; other site
1030843002675	AsnC family; Region: AsnC_trans_reg; pfam01037
1030843002676	uracil transporter; Provisional; Region: PRK10720
1030843002677	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
1030843002678	adenylosuccinate lyase; Provisional; Region: PRK09285
1030843002679	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1030843002680	tetramer interface [polypeptide binding]; other site
1030843002681	active site
1030843002682	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1030843002683	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1030843002684	RNA binding surface [nucleotide binding]; other site
1030843002685	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1030843002686	active site
1030843002687	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1030843002688	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1030843002689	putative dimer interface [polypeptide binding]; other site
1030843002690	putative anticodon binding site; other site
1030843002691	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1030843002692	homodimer interface [polypeptide binding]; other site
1030843002693	motif 1; other site
1030843002694	motif 2; other site
1030843002695	active site
1030843002696	motif 3; other site
1030843002697	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1030843002698	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1030843002699	Clp amino terminal domain; Region: Clp_N; pfam02861
1030843002700	Clp amino terminal domain; Region: Clp_N; pfam02861
1030843002701	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843002702	Walker A motif; other site
1030843002703	ATP binding site [chemical binding]; other site
1030843002704	Walker B motif; other site
1030843002705	arginine finger; other site
1030843002706	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843002707	Walker A motif; other site
1030843002708	ATP binding site [chemical binding]; other site
1030843002709	Walker B motif; other site
1030843002710	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1030843002711	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1030843002712	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1030843002713	cation binding site [ion binding]; other site
1030843002714	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14185
1030843002715	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1030843002716	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1030843002717	homodimer interface [polypeptide binding]; other site
1030843002718	NADP binding site [chemical binding]; other site
1030843002719	substrate binding site [chemical binding]; other site
1030843002720	signal recognition particle protein; Provisional; Region: PRK10867
1030843002721	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1030843002722	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1030843002723	P loop; other site
1030843002724	GTP binding site [chemical binding]; other site
1030843002725	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1030843002726	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1030843002727	tetramerization interface [polypeptide binding]; other site
1030843002728	active site
1030843002729	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1030843002730	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1030843002731	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1030843002732	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1030843002733	RNA polymerase sigma-54 factor; Region: rpoN_sigma; TIGR02395
1030843002734	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1030843002735	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1030843002736	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1030843002737	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1030843002738	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843002739	S-adenosylmethionine binding site [chemical binding]; other site
1030843002740	recombination factor protein RarA; Reviewed; Region: PRK13342
1030843002741	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843002742	Walker A motif; other site
1030843002743	ATP binding site [chemical binding]; other site
1030843002744	Walker B motif; other site
1030843002745	arginine finger; other site
1030843002746	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1030843002747	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843002748	putative transporter; Provisional; Region: PRK10484
1030843002749	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
1030843002750	Na binding site [ion binding]; other site
1030843002751	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1030843002752	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1030843002753	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1030843002754	putative active site [active]
1030843002755	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1030843002756	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
1030843002757	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1030843002758	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1030843002759	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1030843002760	active site
1030843002761	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1030843002762	dimer interface [polypeptide binding]; other site
1030843002763	substrate binding site [chemical binding]; other site
1030843002764	catalytic residues [active]
1030843002765	GSCFA family; Region: GSCFA; pfam08885
1030843002766	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843002767	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1030843002768	TRAM domain; Region: TRAM; cl01282
1030843002769	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843002770	S-adenosylmethionine binding site [chemical binding]; other site
1030843002771	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
1030843002772	This PGM-like (phosphoglucomutase-like) domain is located C-terminal to a mannose-1-phosphate guanyltransferase domain in a protein of unknown function that is found in both prokaryotes and eukaryotes. This domain belongs to the alpha-D-phosphohexomutase...; Region: PGM_like4; cd05803
1030843002773	active site
1030843002774	substrate binding site [chemical binding]; other site
1030843002775	metal binding site [ion binding]; metal-binding site
1030843002776	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1030843002777	DHH family; Region: DHH; pfam01368
1030843002778	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1030843002779	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1030843002780	active site
1030843002781	phosphorylation site [posttranslational modification]
1030843002782	intermolecular recognition site; other site
1030843002783	dimerization interface [polypeptide binding]; other site
1030843002784	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1030843002785	DNA binding site [nucleotide binding]
1030843002786	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1030843002787	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
1030843002788	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843002789	FeS/SAM binding site; other site
1030843002790	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
1030843002791	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1030843002792	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1030843002793	catalytic residues [active]
1030843002794	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
1030843002795	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1030843002796	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1030843002797	propionate/acetate kinase; Provisional; Region: PRK12379
1030843002798	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
1030843002799	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1030843002800	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1030843002801	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
1030843002802	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1030843002803	substrate binding site [chemical binding]; other site
1030843002804	oxyanion hole (OAH) forming residues; other site
1030843002805	trimer interface [polypeptide binding]; other site
1030843002806	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1030843002807	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1030843002808	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1030843002809	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1030843002810	Ligand binding site [chemical binding]; other site
1030843002811	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1030843002812	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1030843002813	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
1030843002814	FAD binding site [chemical binding]; other site
1030843002815	homotetramer interface [polypeptide binding]; other site
1030843002816	substrate binding pocket [chemical binding]; other site
1030843002817	catalytic base [active]
1030843002818	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1030843002819	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
1030843002820	B12 binding domain (B12-BD). This domain binds different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide, it is found in several enzymes, such as glutamate mutase, methionine synthase...; Region: B12-binding; cd02067
1030843002821	B12 binding site [chemical binding]; other site
1030843002822	cobalt ligand [ion binding]; other site
1030843002823	D-Lysine 5,6-aminomutase alpha subunit; Region: Lys-AminoMut_A; pfam09043
1030843002824	ATP-binding cassette domain of MutS homologs; Region: ABC_MutS_homologs; cd03243
1030843002825	Walker A/P-loop; other site
1030843002826	ATP binding site [chemical binding]; other site
1030843002827	Q-loop/lid; other site
1030843002828	ABC transporter signature motif; other site
1030843002829	Walker B; other site
1030843002830	D-loop; other site
1030843002831	H-loop/switch region; other site
1030843002832	Hsp70 protein; Region: HSP70; pfam00012
1030843002833	lysine-2,3-aminomutase; Region: lys_2_3_AblA; TIGR03820
1030843002834	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843002835	FeS/SAM binding site; other site
1030843002836	Lysine-2,3-aminomutase; Region: LAM_C; pfam12544
1030843002837	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1030843002838	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cd05188
1030843002839	NAD(P) binding site [chemical binding]; other site
1030843002840	Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853
1030843002841	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1030843002842	active site 2 [active]
1030843002843	active site 1 [active]
1030843002844	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1030843002845	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1030843002846	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1030843002847	heterodimer interface [polypeptide binding]; other site
1030843002848	active site
1030843002849	FMN binding site [chemical binding]; other site
1030843002850	homodimer interface [polypeptide binding]; other site
1030843002851	substrate binding site [chemical binding]; other site
1030843002852	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
1030843002853	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
1030843002854	FAD binding pocket [chemical binding]; other site
1030843002855	FAD binding motif [chemical binding]; other site
1030843002856	phosphate binding motif [ion binding]; other site
1030843002857	beta-alpha-beta structure motif; other site
1030843002858	NAD binding pocket [chemical binding]; other site
1030843002859	Iron coordination center [ion binding]; other site
1030843002860	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1030843002861	non-specific DNA binding site [nucleotide binding]; other site
1030843002862	salt bridge; other site
1030843002863	sequence-specific DNA binding site [nucleotide binding]; other site
1030843002864	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1030843002865	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843002866	Transposase [DNA replication, recombination, and repair]; Region: COG5433
1030843002867	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
1030843002868	partial transposase in ISPg7; similar to nr, gi|34540280|ref|NP_904759.1| ISPg7, transposase [Porphyromonas gingivalis W83] ISPg7, transposase [Porphyromonas gingivalis W83], percent identity 87.9 in 33 aa, BLASTP E(): 1e-8
1030843002869	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1030843002870	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1030843002871	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1030843002872	protein binding site [polypeptide binding]; other site
1030843002873	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1030843002874	Catalytic dyad [active]
1030843002875	Homologues of TraJ from Bacteroides conjugative transposon; Region: CtnDOT_TraJ; pfam07863
1030843002876	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1030843002877	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1030843002878	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843002879	Walker A/P-loop; other site
1030843002880	ATP binding site [chemical binding]; other site
1030843002881	Q-loop/lid; other site
1030843002882	ABC transporter signature motif; other site
1030843002883	Walker B; other site
1030843002884	D-loop; other site
1030843002885	H-loop/switch region; other site
1030843002886	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1030843002887	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1030843002888	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843002889	Walker A/P-loop; other site
1030843002890	ATP binding site [chemical binding]; other site
1030843002891	Q-loop/lid; other site
1030843002892	ABC transporter signature motif; other site
1030843002893	Walker B; other site
1030843002894	D-loop; other site
1030843002895	H-loop/switch region; other site
1030843002896	Protein of unknown function (DUF1329); Region: DUF1329; pfam07044
1030843002897	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
1030843002898	Sterol-sensing domain of SREBP cleavage-activation; Region: Sterol-sensing; pfam12349
1030843002899	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1030843002900	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1030843002901	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1030843002902	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
1030843002903	active site
1030843002904	catalytic triad [active]
1030843002905	oxyanion hole [active]
1030843002906	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1030843002907	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1030843002908	active site
1030843002909	oxyanion hole [active]
1030843002910	catalytic triad [active]
1030843002911	partial transposase in ISPg2; similar to RefSeq{20100916}, gi|188994406|ref|YP_001928658.1| partial transposase in ISPg2 [Porphyromonas gingivalis ATCC 33277]|, percent identity 86.2 in 65 aa, BLASTP E(): 9e-25
1030843002912	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1030843002913	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1030843002914	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1030843002915	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1030843002916	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1030843002917	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1030843002918	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
1030843002919	putative ligand binding site [chemical binding]; other site
1030843002920	putative NAD binding site [chemical binding]; other site
1030843002921	catalytic site [active]
1030843002922	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
1030843002923	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1030843002924	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1030843002925	catalytic residue [active]
1030843002926	Protein of unknown function (Hypoth_ymh); Region: Hypoth_Ymh; cl09741
1030843002927	BRO family, N-terminal domain; Region: Bro-N; cl10591
1030843002928	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1030843002929	Fic/DOC family; Region: Fic; pfam02661
1030843002930	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1030843002931	non-specific DNA binding site [nucleotide binding]; other site
1030843002932	salt bridge; other site
1030843002933	sequence-specific DNA binding site [nucleotide binding]; other site
1030843002934	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843002935	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1030843002936	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1030843002937	nucleotide binding site [chemical binding]; other site
1030843002938	NEF interaction site [polypeptide binding]; other site
1030843002939	SBD interface [polypeptide binding]; other site
1030843002940	Domain of unknown function (DUF4301); Region: DUF4301; pfam14134
1030843002941	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1030843002942	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1030843002943	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
1030843002944	active site
1030843002945	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1030843002946	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1030843002947	trimer interface [polypeptide binding]; other site
1030843002948	putative metal binding site [ion binding]; other site
1030843002949	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002950	binding surface
1030843002951	TPR motif; other site
1030843002952	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002953	binding surface
1030843002954	TPR motif; other site
1030843002955	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1030843002956	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843002957	TPR motif; other site
1030843002958	binding surface
1030843002959	Predicted double-stranded RNA/RNA-DNA hybrid binding protein [General function prediction only]; Region: COG3341
1030843002960	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
1030843002961	RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner; Region: RNase_H; cd06222
1030843002962	RNA/DNA hybrid binding site [nucleotide binding]; other site
1030843002963	active site
1030843002964	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
1030843002965	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; cl14651
1030843002966	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
1030843002967	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
1030843002968	erythronate-4-phosphate dehydrogenase; Validated; Region: PRK00257
1030843002969	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1030843002970	ligand binding site [chemical binding]; other site
1030843002971	NAD binding site [chemical binding]; other site
1030843002972	catalytic site [active]
1030843002973	homodimer interface [polypeptide binding]; other site
1030843002974	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1030843002975	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1030843002976	NAD(P) binding site [chemical binding]; other site
1030843002977	active site
1030843002978	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1030843002979	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1030843002980	substrate binding pocket [chemical binding]; other site
1030843002981	membrane-bound complex binding site; other site
1030843002982	hinge residues; other site
1030843002983	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1030843002984	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1030843002985	catalytic residue [active]
1030843002986	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1030843002987	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843002988	Walker A/P-loop; other site
1030843002989	ATP binding site [chemical binding]; other site
1030843002990	Q-loop/lid; other site
1030843002991	ABC transporter signature motif; other site
1030843002992	Walker B; other site
1030843002993	D-loop; other site
1030843002994	H-loop/switch region; other site
1030843002995	ABC transporter; Region: ABC_tran_2; pfam12848
1030843002996	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1030843002997	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1030843002998	active site
1030843002999	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1030843003000	Zn binding site [ion binding]; other site
1030843003001	glutamate dehydrogenase; Provisional; Region: PRK14030
1030843003002	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1030843003003	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1030843003004	NAD(P) binding site [chemical binding]; other site
1030843003005	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1030843003006	L-threonine dehydrogenase, extended (e) SDRs; Region: TDH_SDR_e; cd05272
1030843003007	NAD binding site [chemical binding]; other site
1030843003008	homodimer interface [polypeptide binding]; other site
1030843003009	active site
1030843003010	putative substrate binding site [chemical binding]; other site
1030843003011	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1030843003012	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
1030843003013	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1030843003014	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1030843003015	DNA binding residues [nucleotide binding]
1030843003016	dimerization interface [polypeptide binding]; other site
1030843003017	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1030843003018	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1030843003019	active site
1030843003020	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1030843003021	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1030843003022	NAD(P) binding site [chemical binding]; other site
1030843003023	homotetramer interface [polypeptide binding]; other site
1030843003024	homodimer interface [polypeptide binding]; other site
1030843003025	active site
1030843003026	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1030843003027	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1030843003028	GTP-binding protein LepA; Provisional; Region: PRK05433
1030843003029	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1030843003030	G1 box; other site
1030843003031	putative GEF interaction site [polypeptide binding]; other site
1030843003032	GTP/Mg2+ binding site [chemical binding]; other site
1030843003033	Switch I region; other site
1030843003034	G2 box; other site
1030843003035	G3 box; other site
1030843003036	Switch II region; other site
1030843003037	G4 box; other site
1030843003038	G5 box; other site
1030843003039	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1030843003040	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1030843003041	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1030843003042	replicative DNA helicase; Region: DnaB; TIGR00665
1030843003043	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1030843003044	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1030843003045	Walker A motif; other site
1030843003046	ATP binding site [chemical binding]; other site
1030843003047	Walker B motif; other site
1030843003048	DNA binding loops [nucleotide binding]
1030843003049	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843003050	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843003051	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843003052	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1030843003053	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1030843003054	motif 1; other site
1030843003055	active site
1030843003056	motif 2; other site
1030843003057	motif 3; other site
1030843003058	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1030843003059	DHHA1 domain; Region: DHHA1; pfam02272
1030843003060	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1030843003061	active site
1030843003062	dimer interface [polypeptide binding]; other site
1030843003063	metal binding site [ion binding]; metal-binding site
1030843003064	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
1030843003065	A new structural DNA glycosylase; Region: AlkD_like; cd06561
1030843003066	active site
1030843003067	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1030843003068	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1030843003069	putative acyl-acceptor binding pocket; other site
1030843003070	Homologues of TraJ from Bacteroides conjugative transposon; Region: CtnDOT_TraJ; pfam07863
1030843003071	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
1030843003072	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1030843003073	FtsX-like permease family; Region: FtsX; pfam02687
1030843003074	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1030843003075	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1030843003076	nucleotide binding pocket [chemical binding]; other site
1030843003077	K-X-D-G motif; other site
1030843003078	catalytic site [active]
1030843003079	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1030843003080	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1030843003081	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1030843003082	Dimer interface [polypeptide binding]; other site
1030843003083	BRCT sequence motif; other site
1030843003084	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1030843003085	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1030843003086	Coenzyme A binding pocket [chemical binding]; other site
1030843003087	recombination protein RecR; Reviewed; Region: recR; PRK00076
1030843003088	RecR protein; Region: RecR; pfam02132
1030843003089	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1030843003090	putative active site [active]
1030843003091	putative metal-binding site [ion binding]; other site
1030843003092	tetramer interface [polypeptide binding]; other site
1030843003093	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1030843003094	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1030843003095	homodimer interface [polypeptide binding]; other site
1030843003096	oligonucleotide binding site [chemical binding]; other site
1030843003097	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1030843003098	IHF - DNA interface [nucleotide binding]; other site
1030843003099	IHF dimer interface [polypeptide binding]; other site
1030843003100	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1030843003101	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
1030843003102	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
1030843003103	ATP cone domain; Region: ATP-cone; pfam03477
1030843003104	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1030843003105	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1030843003106	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
1030843003107	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843003108	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
1030843003109	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
1030843003110	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843003111	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1030843003112	Archaeal ATPase; Region: Arch_ATPase; pfam01637
1030843003113	NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; Region: nqrA; TIGR01936
1030843003114	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
1030843003115	NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit; Region: nqrB; TIGR01937
1030843003116	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
1030843003117	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
1030843003118	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
1030843003119	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
1030843003120	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
1030843003121	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1030843003122	catalytic loop [active]
1030843003123	iron binding site [ion binding]; other site
1030843003124	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
1030843003125	FAD binding pocket [chemical binding]; other site
1030843003126	FAD binding motif [chemical binding]; other site
1030843003127	phosphate binding motif [ion binding]; other site
1030843003128	beta-alpha-beta structure motif; other site
1030843003129	NAD binding pocket [chemical binding]; other site
1030843003130	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1030843003131	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1030843003132	catalytic residues [active]
1030843003133	Outer membrane protein Omp28; Region: Omp28; pfam11551
1030843003134	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843003135	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_13; cd12178
1030843003136	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1030843003137	putative ligand binding site [chemical binding]; other site
1030843003138	putative NAD binding site [chemical binding]; other site
1030843003139	catalytic site [active]
1030843003140	potential frameshift: common BLAST hit: gi|34541741|ref|NP_906220.1| sugar transporter
1030843003141	L-fucose transporter; Provisional; Region: PRK10133; cl17665
1030843003142	L-fucose transporter; Provisional; Region: PRK10133; cl17665
1030843003143	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843003144	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
1030843003145	Domain of unknown function, B. Theta Gene description (DUF3868); Region: DUF3868; pfam12984
1030843003146	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1030843003147	ligand binding site [chemical binding]; other site
1030843003148	glycyl-tRNA synthetase; Provisional; Region: PRK04173
1030843003149	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1030843003150	motif 1; other site
1030843003151	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
1030843003152	active site
1030843003153	motif 2; other site
1030843003154	motif 3; other site
1030843003155	HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for...; Region: HGTP_anticodon; cl00266
1030843003156	anticodon binding site; other site
1030843003157	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1030843003158	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1030843003159	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1030843003160	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1030843003161	Helix-turn-helix domain; Region: HTH_18; pfam12833
1030843003162	protoporphyrinogen oxidase; Region: proto_IX_ox; TIGR00562
1030843003163	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1030843003164	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
1030843003165	M28 Zn-Peptidases; Region: M28_like_6; cd08656
1030843003166	Peptidase family M28; Region: Peptidase_M28; pfam04389
1030843003167	metal binding site [ion binding]; metal-binding site
1030843003168	RNA methyltransferase, RsmE family; Region: TIGR00046
1030843003169	RNA methyltransferase; Region: Methyltrans_RNA; pfam04452
1030843003170	TraB family; Region: TraB; pfam01963
1030843003171	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843003172	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1030843003173	active site
1030843003174	Int/Topo IB signature motif; other site
1030843003175	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1030843003176	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1030843003177	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
1030843003178	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
1030843003179	ligand binding site [chemical binding]; other site
1030843003180	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1030843003181	xanthine permease; Region: pbuX; TIGR03173
1030843003182	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1030843003183	active site
1030843003184	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
1030843003185	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1030843003186	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1030843003187	NodB motif; other site
1030843003188	active site
1030843003189	catalytic site [active]
1030843003190	metal binding site [ion binding]; metal-binding site
1030843003191	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
1030843003192	GTP-binding protein Der; Reviewed; Region: PRK00093
1030843003193	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1030843003194	G1 box; other site
1030843003195	GTP/Mg2+ binding site [chemical binding]; other site
1030843003196	Switch I region; other site
1030843003197	G2 box; other site
1030843003198	Switch II region; other site
1030843003199	G3 box; other site
1030843003200	G4 box; other site
1030843003201	G5 box; other site
1030843003202	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1030843003203	G1 box; other site
1030843003204	GTP/Mg2+ binding site [chemical binding]; other site
1030843003205	Switch I region; other site
1030843003206	G2 box; other site
1030843003207	G3 box; other site
1030843003208	Switch II region; other site
1030843003209	G4 box; other site
1030843003210	G5 box; other site
1030843003211	GTPase Era; Reviewed; Region: era; PRK00089
1030843003212	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1030843003213	G1 box; other site
1030843003214	GTP/Mg2+ binding site [chemical binding]; other site
1030843003215	Switch I region; other site
1030843003216	G2 box; other site
1030843003217	Switch II region; other site
1030843003218	G3 box; other site
1030843003219	G4 box; other site
1030843003220	G5 box; other site
1030843003221	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cl00098
1030843003222	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1030843003223	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1030843003224	dimer interface [polypeptide binding]; other site
1030843003225	active site
1030843003226	CoA binding pocket [chemical binding]; other site
1030843003227	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
1030843003228	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
1030843003229	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
1030843003230	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2; Region: Mfa2; pfam08842
1030843003231	Major fimbrial subunit protein (FimA); Region: P_gingi_FimA; pfam06321
1030843003232	Domain of unknown function, B. Theta Gene description (DUF3868); Region: DUF3868; pfam12984
1030843003233	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1030843003234	ligand binding site [chemical binding]; other site
1030843003235	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
1030843003236	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1030843003237	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1030843003238	catalytic residue [active]
1030843003239	Helix-turn-helix domain; Region: HTH_18; pfam12833
1030843003240	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1030843003241	glyceraldehyde-3-phosphate dehydrogenase; Provisional; Region: PTZ00023
1030843003242	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1030843003243	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1030843003244	partial transposase in ISPg2; similar to nr, gi|188994035|ref|YP_001928287.1| partial transposase in ISPg2 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg2 [Porphyromonas gingivalis ATCC 33277], percent identity 97.9 in 95 aa, BLASTP E(): 2e-46
1030843003245	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1030843003246	homodimer interface [polypeptide binding]; other site
1030843003247	active site
1030843003248	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1030843003249	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1030843003250	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1030843003251	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1030843003252	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14521
1030843003253	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1030843003254	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843003255	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1030843003256	thiS-thiF/thiG interaction site; other site
1030843003257	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1030843003258	ThiC-associated domain; Region: ThiC-associated; pfam13667
1030843003259	ThiC family; Region: ThiC; pfam01964
1030843003260	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1030843003261	thiamine phosphate binding site [chemical binding]; other site
1030843003262	active site
1030843003263	pyrophosphate binding site [ion binding]; other site
1030843003264	HMP-P kinase/thiamin-monophosphate pyrophosphorylase; Region: PLN02898
1030843003265	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1030843003266	substrate binding site [chemical binding]; other site
1030843003267	dimer interface [polypeptide binding]; other site
1030843003268	ATP binding site [chemical binding]; other site
1030843003269	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1030843003270	thiamine phosphate binding site [chemical binding]; other site
1030843003271	active site
1030843003272	pyrophosphate binding site [ion binding]; other site
1030843003273	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1030843003274	ThiS interaction site; other site
1030843003275	putative active site [active]
1030843003276	tetramer interface [polypeptide binding]; other site
1030843003277	thiazole biosynthesis protein ThiH; Region: thiH; TIGR02351
1030843003278	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843003279	FeS/SAM binding site; other site
1030843003280	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1030843003281	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1030843003282	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843003283	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843003284	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
1030843003285	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1030843003286	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1030843003287	ATP binding site [chemical binding]; other site
1030843003288	Mg++ binding site [ion binding]; other site
1030843003289	motif III; other site
1030843003290	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843003291	nucleotide binding region [chemical binding]; other site
1030843003292	ATP-binding site [chemical binding]; other site
1030843003293	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1030843003294	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1030843003295	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1030843003296	active site
1030843003297	Family of unknown function (DUF490); Region: DUF490; pfam04357
1030843003298	Surface antigen; Region: Bac_surface_Ag; pfam01103
1030843003299	Family of unknown function (DUF490); Region: DUF490; pfam04357
1030843003300	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1030843003301	homooctamer interface [polypeptide binding]; other site
1030843003302	active site
1030843003303	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1030843003304	Cation efflux family; Region: Cation_efflux; pfam01545
1030843003305	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1030843003306	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1030843003307	SelR domain; Region: SelR; pfam01641
1030843003308	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1030843003309	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
1030843003310	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1030843003311	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1030843003312	active site
1030843003313	HIGH motif; other site
1030843003314	dimer interface [polypeptide binding]; other site
1030843003315	KMSKS motif; other site
1030843003316	amino acid/peptide transporter (Peptide:H+ symporter), bacterial; Region: yjdL_sub1_fam; TIGR00924
1030843003317	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1030843003318	POT family; Region: PTR2; cl17359
1030843003319	biotin synthase; Region: bioB; TIGR00433
1030843003320	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843003321	FeS/SAM binding site; other site
1030843003322	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1030843003323	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK06173
1030843003324	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1030843003325	inhibitor-cofactor binding pocket; inhibition site
1030843003326	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843003327	catalytic residue [active]
1030843003328	partial transposase in ISPg1; similar to nr, gi|188994872|ref|YP_001929124.1| partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277], percent identity 98 in 50 aa, BLASTP E(): 2e-20
1030843003329	partial transposase in ISPg6; similar to nr, gi|188993975|ref|YP_001928227.1| partial transposase in ISPg6 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg6 [Porphyromonas gingivalis ATCC 33277], percent identity 96.7 in 61 aa, BLASTP E(): 2e-25
1030843003330	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843003331	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843003332	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843003333	Homologues of TraJ from Bacteroides conjugative transposon; Region: CtnDOT_TraJ; pfam07863
1030843003334	partial transposase in ISPg6; similar to nr, gi|34540798|ref|NP_905277.1| ISPg6, transposase [Porphyromonas gingivalis W83] ISPg6, transposase [Porphyromonas gingivalis W83], percent identity 100 in 30 aa, BLASTP E(): 1e-8
1030843003335	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
1030843003336	partial transposase in ISPg4; similar to nr, gi|34539897|ref|NP_904376.1| ISPg4 transposase [Porphyromonas gingivalis W83] ISPg4, transposase [Porphyromonas gingivalis W83] ISPg4 transposase [Porphyromonas gingivalis W83] ISPg4, transposase [Porphyromonas gingivalis W83], percent identity 78.9 in 57 aa, BLASTP E(): 1e-18
1030843003337	Putative catalytic domain of uncharacterized prokaryotic polysaccharide deacetylases similar to bacterial PuuE allantoinases and Helicobacter pylori peptidoglycan deacetylase (HpPgdA); Region: CE4_PuuE_HpPgdA_like_2; cd10941
1030843003338	putative active site [active]
1030843003339	putative catalytic site [active]
1030843003340	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1030843003341	active site
1030843003342	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
1030843003343	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1030843003344	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1030843003345	ATP-binding site [chemical binding]; other site
1030843003346	Sugar specificity; other site
1030843003347	Pyrimidine base specificity; other site
1030843003348	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1030843003349	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1030843003350	substrate-cofactor binding pocket; other site
1030843003351	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843003352	catalytic residue [active]
1030843003353	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1030843003354	putative ADP-ribose binding site [chemical binding]; other site
1030843003355	putative active site [active]
1030843003356	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1030843003357	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1030843003358	putative active site [active]
1030843003359	putative metal binding site [ion binding]; other site
1030843003360	Domain of unknown function DUF59; Region: DUF59; cl00941
1030843003361	chaperone protein DnaJ; Provisional; Region: PRK14289
1030843003362	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1030843003363	HSP70 interaction site [polypeptide binding]; other site
1030843003364	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1030843003365	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1030843003366	dimer interface [polypeptide binding]; other site
1030843003367	GrpE; Region: GrpE; pfam01025
1030843003368	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1030843003369	dimer interface [polypeptide binding]; other site
1030843003370	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1030843003371	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1030843003372	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1030843003373	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1030843003374	ATP binding site [chemical binding]; other site
1030843003375	putative Mg++ binding site [ion binding]; other site
1030843003376	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843003377	nucleotide binding region [chemical binding]; other site
1030843003378	ATP-binding site [chemical binding]; other site
1030843003379	TRCF domain; Region: TRCF; pfam03461
1030843003380	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
1030843003381	active site
1030843003382	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1030843003383	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1030843003384	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1030843003385	minor groove reading motif; other site
1030843003386	helix-hairpin-helix signature motif; other site
1030843003387	substrate binding pocket [chemical binding]; other site
1030843003388	active site
1030843003389	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1030843003390	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1030843003391	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1030843003392	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1030843003393	dimer interface [polypeptide binding]; other site
1030843003394	motif 1; other site
1030843003395	active site
1030843003396	motif 2; other site
1030843003397	motif 3; other site
1030843003398	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1030843003399	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1030843003400	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1030843003401	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1030843003402	AhpC/TSA family; Region: AhpC-TSA; pfam00578
1030843003403	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1030843003404	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1030843003405	active site
1030843003406	substrate binding site [chemical binding]; other site
1030843003407	cosubstrate binding site; other site
1030843003408	catalytic site [active]
1030843003409	acyl carrier protein; Provisional; Region: acpP; PRK00982
1030843003410	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1030843003411	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1030843003412	dimer interface [polypeptide binding]; other site
1030843003413	active site
1030843003414	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
1030843003415	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1030843003416	dimerization interface [polypeptide binding]; other site
1030843003417	active site
1030843003418	metal binding site [ion binding]; metal-binding site
1030843003419	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1030843003420	dsRNA binding site [nucleotide binding]; other site
1030843003421	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1030843003422	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1030843003423	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1030843003424	Protein export membrane protein; Region: SecD_SecF; pfam02355
1030843003425	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1030843003426	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1030843003427	Coenzyme A binding pocket [chemical binding]; other site
1030843003428	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1030843003429	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1030843003430	Metal binding protein ZntC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: ZntC; cd01018
1030843003431	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1030843003432	putative metal binding residues [ion binding]; other site
1030843003433	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1030843003434	16S/18S rRNA binding site [nucleotide binding]; other site
1030843003435	S13e-L30e interaction site [polypeptide binding]; other site
1030843003436	25S rRNA binding site [nucleotide binding]; other site
1030843003437	Fructose-1.6-bisphosphate aldolase found in gram +/- bacteria; Region: FBP_aldolase_I_bact; cd00949
1030843003438	putative active site [active]
1030843003439	catalytic residue [active]
1030843003440	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1030843003441	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1030843003442	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1030843003443	selenophosphate synthetase; Provisional; Region: PRK00943
1030843003444	dimerization interface [polypeptide binding]; other site
1030843003445	putative ATP binding site [chemical binding]; other site
1030843003446	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1030843003447	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1030843003448	cysteine desulfurase family protein; Region: am_tr_V_EF2568; TIGR01977
1030843003449	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1030843003450	catalytic residue [active]
1030843003451	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
1030843003452	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
1030843003453	sugar binding site [chemical binding]; other site
1030843003454	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1030843003455	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1030843003456	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1030843003457	TPP-binding site [chemical binding]; other site
1030843003458	dimer interface [polypeptide binding]; other site
1030843003459	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1030843003460	PYR/PP interface [polypeptide binding]; other site
1030843003461	dimer interface [polypeptide binding]; other site
1030843003462	TPP binding site [chemical binding]; other site
1030843003463	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1030843003464	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1030843003465	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1030843003466	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1030843003467	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1030843003468	putative NAD(P) binding site [chemical binding]; other site
1030843003469	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1030843003470	FtsX-like permease family; Region: FtsX; pfam02687
1030843003471	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1030843003472	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1030843003473	FtsX-like permease family; Region: FtsX; pfam02687
1030843003474	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1030843003475	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1030843003476	Walker A/P-loop; other site
1030843003477	ATP binding site [chemical binding]; other site
1030843003478	Q-loop/lid; other site
1030843003479	ABC transporter signature motif; other site
1030843003480	Walker B; other site
1030843003481	D-loop; other site
1030843003482	H-loop/switch region; other site
1030843003483	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1030843003484	HlyD family secretion protein; Region: HlyD_3; pfam13437
1030843003485	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1030843003486	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
1030843003487	Bacteroidetes-specific putative membrane protein; Region: Bac_Flav_fam_1; TIGR03519
1030843003488	gliding motility-associated lipoprotein GldK; Region: GldK; TIGR03525
1030843003489	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
1030843003490	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
1030843003491	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
1030843003492	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
1030843003493	GldM N-terminal domain; Region: GldM_N; pfam12081
1030843003494	GldM C-terminal domain; Region: GldM_C; pfam12080
1030843003495	gliding motility associated protien GldN; Region: GldN; TIGR03523
1030843003496	Chromate transporter; Region: Chromate_transp; pfam02417
1030843003497	Chromate transporter; Region: Chromate_transp; pfam02417
1030843003498	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1030843003499	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1030843003500	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843003501	Glycosyltransferase like family 2; Region: Glyco_tranf_2_2; pfam10111
1030843003502	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1030843003503	active site
1030843003504	N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; cl17476
1030843003505	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1030843003506	DNA protecting protein DprA; Region: dprA; TIGR00732
1030843003507	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1030843003508	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1030843003509	dimerization interface [polypeptide binding]; other site
1030843003510	ATP binding site [chemical binding]; other site
1030843003511	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1030843003512	dimerization interface [polypeptide binding]; other site
1030843003513	ATP binding site [chemical binding]; other site
1030843003514	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1030843003515	putative active site [active]
1030843003516	catalytic triad [active]
1030843003517	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843003518	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843003519	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843003520	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
1030843003521	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1030843003522	Coenzyme A binding pocket [chemical binding]; other site
1030843003523	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
1030843003524	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1030843003525	Propeptide_C25; Region: Propeptide_C25; pfam08126
1030843003526	gingipain subgroup of the Peptidase C25 family N-terminal domain; Region: Peptidase_C25_N_gingipain; cd10913
1030843003527	active site
1030843003528	Peptidase family C25, C terminal ig-like domain; Region: Peptidase_C25_C; pfam03785
1030843003529	Domain of unknown function (DUF2436); Region: DUF2436; pfam10365
1030843003530	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843003531	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843003532	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843003533	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843003534	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843003535	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843003536	partial transposase in ISPg3; similar to nr, gi|188995526|ref|YP_001929778.1| partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277], percent identity 95.3 in 43 aa, BLASTP E(): 4e-17
1030843003537	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843003538	TPR motif; other site
1030843003539	TPR repeat; Region: TPR_11; pfam13414
1030843003540	binding surface
1030843003541	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843003542	binding surface
1030843003543	TPR motif; other site
1030843003544	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843003545	TPR motif; other site
1030843003546	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246
1030843003547	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1030843003548	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1030843003549	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1030843003550	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
1030843003551	SLBB domain; Region: SLBB; pfam10531
1030843003552	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1030843003553	electron transport complex, RnfABCDGE type, D subunit; Region: rnfD; TIGR01946
1030843003554	electron transport complex, RnfABCDGE type, G subunit; Region: rnfG; TIGR01947
1030843003555	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1030843003556	electron transport complex, RnfABCDGE type, A subunit; Region: rnfA; TIGR01943
1030843003557	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1030843003558	ApbE family; Region: ApbE; pfam02424
1030843003559	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
1030843003560	putative FMN binding site [chemical binding]; other site
1030843003561	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1030843003562	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1030843003563	Ligand binding site; other site
1030843003564	Putative Catalytic site; other site
1030843003565	DXD motif; other site
1030843003566	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
1030843003567	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1030843003568	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1030843003569	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1030843003570	seryl-tRNA synthetase; Provisional; Region: PRK05431
1030843003571	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1030843003572	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1030843003573	dimer interface [polypeptide binding]; other site
1030843003574	active site
1030843003575	motif 1; other site
1030843003576	motif 2; other site
1030843003577	motif 3; other site
1030843003578	Peptidase family M49; Region: Peptidase_M49; pfam03571
1030843003579	A new structural DNA glycosylase; Region: AlkD_like; cl11434
1030843003580	active site
1030843003581	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
1030843003582	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
1030843003583	membrane ATPase/protein kinase; Provisional; Region: PRK09435
1030843003584	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
1030843003585	Walker A; other site
1030843003586	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1030843003587	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1030843003588	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1030843003589	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1030843003590	active sites [active]
1030843003591	tetramer interface [polypeptide binding]; other site
1030843003592	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
1030843003593	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
1030843003594	Nucleoside recognition; Region: Gate; pfam07670
1030843003595	imidazolonepropionase; Validated; Region: PRK09356
1030843003596	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1030843003597	active site
1030843003598	Glutamate formiminotransferase [Amino acid transport and metabolism]; Region: COG3643
1030843003599	Formiminotransferase domain, N-terminal subdomain; Region: FTCD_N; pfam07837
1030843003600	Formiminotransferase domain; Region: FTCD; pfam02971
1030843003601	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843003602	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1030843003603	transcription termination factor Rho; Provisional; Region: PRK12608
1030843003604	RNA binding site [nucleotide binding]; other site
1030843003605	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1030843003606	multimer interface [polypeptide binding]; other site
1030843003607	Walker A motif; other site
1030843003608	ATP binding site [chemical binding]; other site
1030843003609	Walker B motif; other site
1030843003610	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1030843003611	EamA-like transporter family; Region: EamA; pfam00892
1030843003612	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1030843003613	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1030843003614	Ligand binding site; other site
1030843003615	Putative Catalytic site; other site
1030843003616	DXD motif; other site
1030843003617	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1030843003618	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1030843003619	methionine gamma-lyase; Provisional; Region: PRK06234
1030843003620	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1030843003621	homodimer interface [polypeptide binding]; other site
1030843003622	substrate-cofactor binding pocket; other site
1030843003623	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843003624	catalytic residue [active]
1030843003625	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1030843003626	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1030843003627	active site
1030843003628	metal binding site [ion binding]; metal-binding site
1030843003629	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1030843003630	G1 box; other site
1030843003631	GTP/Mg2+ binding site [chemical binding]; other site
1030843003632	Switch I region; other site
1030843003633	G2 box; other site
1030843003634	G3 box; other site
1030843003635	Switch II region; other site
1030843003636	G4 box; other site
1030843003637	G5 box; other site
1030843003638	UDP-glucose 4-epimerase; Region: PLN02240
1030843003639	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1030843003640	NAD binding site [chemical binding]; other site
1030843003641	homodimer interface [polypeptide binding]; other site
1030843003642	active site
1030843003643	substrate binding site [chemical binding]; other site
1030843003644	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1030843003645	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1030843003646	generic binding surface II; other site
1030843003647	ssDNA binding site; other site
1030843003648	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1030843003649	ATP binding site [chemical binding]; other site
1030843003650	putative Mg++ binding site [ion binding]; other site
1030843003651	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843003652	nucleotide binding region [chemical binding]; other site
1030843003653	ATP-binding site [chemical binding]; other site
1030843003654	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1030843003655	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843003656	active site
1030843003657	motif I; other site
1030843003658	motif II; other site
1030843003659	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1030843003660	Leucine-rich repeats; other site
1030843003661	Substrate binding site [chemical binding]; other site
1030843003662	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843003663	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
1030843003664	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
1030843003665	catalytic site [active]
1030843003666	BNR repeat-like domain; Region: BNR_2; pfam13088
1030843003667	Asp-box motif; other site
1030843003668	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
1030843003669	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1030843003670	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1030843003671	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1030843003672	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1030843003673	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1030843003674	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1030843003675	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1030843003676	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1030843003677	Repair protein; Region: Repair_PSII; pfam04536
1030843003678	Ribosomal protein S27; Region: Ribosomal_S27e; cl00897
1030843003679	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
1030843003680	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1030843003681	substrate binding pocket [chemical binding]; other site
1030843003682	membrane-bound complex binding site; other site
1030843003683	hinge residues; other site
1030843003684	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
1030843003685	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1030843003686	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1030843003687	putative RNA binding site [nucleotide binding]; other site
1030843003688	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843003689	S-adenosylmethionine binding site [chemical binding]; other site
1030843003690	DEDDy 3'-5' exonuclease domain of WRN and similar proteins; Region: WRN_exo; cd06141
1030843003691	catalytic site [active]
1030843003692	putative active site [active]
1030843003693	putative substrate binding site [chemical binding]; other site
1030843003694	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1030843003695	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843003696	ATP binding site [chemical binding]; other site
1030843003697	Mg2+ binding site [ion binding]; other site
1030843003698	G-X-G motif; other site
1030843003699	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1030843003700	anchoring element; other site
1030843003701	dimer interface [polypeptide binding]; other site
1030843003702	ATP binding site [chemical binding]; other site
1030843003703	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
1030843003704	active site
1030843003705	putative metal-binding site [ion binding]; other site
1030843003706	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1030843003707	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1030843003708	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1030843003709	active site
1030843003710	(T/H)XGH motif; other site
1030843003711	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
1030843003712	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1030843003713	23S rRNA interface [nucleotide binding]; other site
1030843003714	L3 interface [polypeptide binding]; other site
1030843003715	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1030843003716	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1030843003717	rRNA interaction site [nucleotide binding]; other site
1030843003718	S8 interaction site; other site
1030843003719	putative laminin-1 binding site; other site
1030843003720	elongation factor Ts; Provisional; Region: tsf; PRK09377
1030843003721	UBA/TS-N domain; Region: UBA; pfam00627
1030843003722	Elongation factor TS; Region: EF_TS; pfam00889
1030843003723	Elongation factor TS; Region: EF_TS; pfam00889
1030843003724	excinuclease ABC subunit B; Provisional; Region: PRK05298
1030843003725	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1030843003726	ATP binding site [chemical binding]; other site
1030843003727	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843003728	nucleotide binding region [chemical binding]; other site
1030843003729	ATP-binding site [chemical binding]; other site
1030843003730	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1030843003731	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1030843003732	RIP metalloprotease RseP; Region: TIGR00054
1030843003733	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1030843003734	active site
1030843003735	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1030843003736	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1030843003737	protein binding site [polypeptide binding]; other site
1030843003738	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1030843003739	putative substrate binding region [chemical binding]; other site
1030843003740	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1030843003741	MutS domain III; Region: MutS_III; pfam05192
1030843003742	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843003743	Walker A/P-loop; other site
1030843003744	ATP binding site [chemical binding]; other site
1030843003745	Q-loop/lid; other site
1030843003746	ABC transporter signature motif; other site
1030843003747	Walker B; other site
1030843003748	D-loop; other site
1030843003749	H-loop/switch region; other site
1030843003750	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
1030843003751	Smr domain; Region: Smr; pfam01713
1030843003752	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1030843003753	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1030843003754	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1030843003755	active site
1030843003756	Int/Topo IB signature motif; other site
1030843003757	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1030843003758	30S subunit binding site; other site
1030843003759	elongation factor Tu; Reviewed; Region: PRK12735
1030843003760	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1030843003761	G1 box; other site
1030843003762	GEF interaction site [polypeptide binding]; other site
1030843003763	GTP/Mg2+ binding site [chemical binding]; other site
1030843003764	Switch I region; other site
1030843003765	G2 box; other site
1030843003766	G3 box; other site
1030843003767	Switch II region; other site
1030843003768	G4 box; other site
1030843003769	G5 box; other site
1030843003770	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1030843003771	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1030843003772	Antibiotic Binding Site [chemical binding]; other site
1030843003773	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
1030843003774	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1030843003775	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1030843003776	putative homodimer interface [polypeptide binding]; other site
1030843003777	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1030843003778	heterodimer interface [polypeptide binding]; other site
1030843003779	homodimer interface [polypeptide binding]; other site
1030843003780	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1030843003781	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1030843003782	23S rRNA interface [nucleotide binding]; other site
1030843003783	L7/L12 interface [polypeptide binding]; other site
1030843003784	putative thiostrepton binding site; other site
1030843003785	L25 interface [polypeptide binding]; other site
1030843003786	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1030843003787	mRNA/rRNA interface [nucleotide binding]; other site
1030843003788	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1030843003789	23S rRNA interface [nucleotide binding]; other site
1030843003790	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1030843003791	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1030843003792	core dimer interface [polypeptide binding]; other site
1030843003793	peripheral dimer interface [polypeptide binding]; other site
1030843003794	L10 interface [polypeptide binding]; other site
1030843003795	L11 interface [polypeptide binding]; other site
1030843003796	putative EF-Tu interaction site [polypeptide binding]; other site
1030843003797	putative EF-G interaction site [polypeptide binding]; other site
1030843003798	RNA polymerase beta subunit; Region: RNA_pol_Rpb2_1; pfam04563
1030843003799	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1030843003800	DNA-directed RNA polymerase, beta subunit; Region: rpoB; TIGR02013
1030843003801	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1030843003802	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1030843003803	RPB12 interaction site [polypeptide binding]; other site
1030843003804	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1030843003805	RPB11 interaction site [polypeptide binding]; other site
1030843003806	RPB12 interaction site [polypeptide binding]; other site
1030843003807	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1030843003808	RPB3 interaction site [polypeptide binding]; other site
1030843003809	RPB1 interaction site [polypeptide binding]; other site
1030843003810	RPB11 interaction site [polypeptide binding]; other site
1030843003811	RPB10 interaction site [polypeptide binding]; other site
1030843003812	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1030843003813	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1030843003814	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1030843003815	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1030843003816	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1030843003817	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1030843003818	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1030843003819	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1030843003820	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1030843003821	DNA binding site [nucleotide binding]
1030843003822	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1030843003823	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1030843003824	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1030843003825	ligand binding site [chemical binding]; other site
1030843003826	flexible hinge region; other site
1030843003827	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1030843003828	putative switch regulator; other site
1030843003829	non-specific DNA interactions [nucleotide binding]; other site
1030843003830	DNA binding site [nucleotide binding]
1030843003831	sequence specific DNA binding site [nucleotide binding]; other site
1030843003832	putative cAMP binding site [chemical binding]; other site
1030843003833	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1030843003834	recombination protein F; Reviewed; Region: recF; PRK00064
1030843003835	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843003836	Walker A/P-loop; other site
1030843003837	ATP binding site [chemical binding]; other site
1030843003838	Q-loop/lid; other site
1030843003839	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843003840	ABC transporter signature motif; other site
1030843003841	Walker B; other site
1030843003842	D-loop; other site
1030843003843	H-loop/switch region; other site
1030843003844	GldH lipoprotein; Region: GldH_lipo; cl11905
1030843003845	PSP1 C-terminal conserved region; Region: PSP1; cl00770
1030843003846	phosphodiesterase; Provisional; Region: PRK12704
1030843003847	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1030843003848	Zn2+ binding site [ion binding]; other site
1030843003849	Mg2+ binding site [ion binding]; other site
1030843003850	Cell division protein ZapA; Region: ZapA; pfam05164
1030843003851	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843003852	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843003853	Cleaved Adhesin Domain; Region: Cleaved_Adhesin; pfam07675
1030843003854	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843003855	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1030843003856	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843003857	ATP binding site [chemical binding]; other site
1030843003858	Mg2+ binding site [ion binding]; other site
1030843003859	G-X-G motif; other site
1030843003860	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1030843003861	ATP binding site [chemical binding]; other site
1030843003862	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
1030843003863	OstA-like protein; Region: OstA_2; pfam13100
1030843003864	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1030843003865	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1030843003866	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1030843003867	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1030843003868	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1030843003869	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1030843003870	ATP binding site [chemical binding]; other site
1030843003871	putative Mg++ binding site [ion binding]; other site
1030843003872	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843003873	nucleotide binding region [chemical binding]; other site
1030843003874	ATP-binding site [chemical binding]; other site
1030843003875	RQC domain; Region: RQC; pfam09382
1030843003876	HRDC domain; Region: HRDC; pfam00570
1030843003877	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1030843003878	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
1030843003879	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843003880	Walker A motif; other site
1030843003881	ATP binding site [chemical binding]; other site
1030843003882	Walker B motif; other site
1030843003883	arginine finger; other site
1030843003884	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1030843003885	Clp protease; Region: CLP_protease; pfam00574
1030843003886	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1030843003887	oligomer interface [polypeptide binding]; other site
1030843003888	active site residues [active]
1030843003889	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1030843003890	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1030843003891	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1030843003892	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1030843003893	seadornavirus VP3 protein; Region: seadorna_VP3; TIGR04232
1030843003894	Lumazine-binding domain; Region: Lumazine_bd; pfam12870
1030843003895	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1030843003896	Putative esterase; Region: Esterase; pfam00756
1030843003897	S-formylglutathione hydrolase; Region: PLN02442
1030843003898	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1030843003899	Outer membrane efflux protein; Region: OEP; pfam02321
1030843003900	Outer membrane efflux protein; Region: OEP; pfam02321
1030843003901	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1030843003902	Protein export membrane protein; Region: SecD_SecF; cl14618
1030843003903	Protein export membrane protein; Region: SecD_SecF; cl14618
1030843003904	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1030843003905	HlyD family secretion protein; Region: HlyD_3; pfam13437
1030843003906	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
1030843003907	active site clefts [active]
1030843003908	zinc binding site [ion binding]; other site
1030843003909	dimer interface [polypeptide binding]; other site
1030843003910	2-oxoacid:acceptor oxidoreductase, alpha subunit; Region: OAFO_sf; TIGR03710
1030843003911	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1030843003912	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1030843003913	dimer interface [polypeptide binding]; other site
1030843003914	PYR/PP interface [polypeptide binding]; other site
1030843003915	TPP binding site [chemical binding]; other site
1030843003916	substrate binding site [chemical binding]; other site
1030843003917	2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed; Region: PRK11867
1030843003918	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
1030843003919	TPP-binding site [chemical binding]; other site
1030843003920	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1030843003921	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843003922	S-adenosylmethionine binding site [chemical binding]; other site
1030843003923	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1030843003924	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
1030843003925	putative SAM binding site [chemical binding]; other site
1030843003926	homodimer interface [polypeptide binding]; other site
1030843003927	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
1030843003928	Chain length determinant protein; Region: Wzz; cl15801
1030843003929	polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Region: pepcterm_ChnLen; TIGR03007
1030843003930	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1030843003931	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1030843003932	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1030843003933	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1030843003934	SLBB domain; Region: SLBB; pfam10531
1030843003935	GLPGLI family protein; Region: GLPGLI; TIGR01200
1030843003936	GLPGLI family protein; Region: GLPGLI; TIGR01200
1030843003937	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843003938	OPT oligopeptide transporter protein; Region: OPT; pfam03169
1030843003939	putative oligopeptide transporter, OPT family; Region: TIGR00733
1030843003940	peptidase T; Region: peptidase-T; TIGR01882
1030843003941	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1030843003942	metal binding site [ion binding]; metal-binding site
1030843003943	dimer interface [polypeptide binding]; other site
1030843003944	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
1030843003945	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1030843003946	ATP binding site [chemical binding]; other site
1030843003947	substrate interface [chemical binding]; other site
1030843003948	pantothenate kinase; Reviewed; Region: PRK13320
1030843003949	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1030843003950	TPR repeat; Region: TPR_11; pfam13414
1030843003951	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843003952	binding surface
1030843003953	TPR motif; other site
1030843003954	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1030843003955	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1030843003956	Domain of unknown function DUF21; Region: DUF21; pfam01595
1030843003957	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1030843003958	Transporter associated domain; Region: CorC_HlyC; smart01091
1030843003959	SurA N-terminal domain; Region: SurA_N_3; cl07813
1030843003960	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1030843003961	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
1030843003962	Predicted membrane protein [Function unknown]; Region: COG3174
1030843003963	Domain of unknown function (DUF4010); Region: DUF4010; pfam13194
1030843003964	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1030843003965	DNA methylase; Region: N6_N4_Mtase; pfam01555
1030843003966	MjaI restriction endonuclease; Region: RE_MjaI; pfam09568
1030843003967	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1030843003968	DNA binding site [nucleotide binding]
1030843003969	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1030843003970	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1030843003971	putative substrate translocation pore; other site
1030843003972	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
1030843003973	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1030843003974	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1030843003975	GDP-binding site [chemical binding]; other site
1030843003976	ACT binding site; other site
1030843003977	IMP binding site; other site
1030843003978	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
1030843003979	metal binding site 2 [ion binding]; metal-binding site
1030843003980	putative DNA binding helix; other site
1030843003981	metal binding site 1 [ion binding]; metal-binding site
1030843003982	structural Zn2+ binding site [ion binding]; other site
1030843003983	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1030843003984	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1030843003985	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1030843003986	ligand binding site [chemical binding]; other site
1030843003987	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1030843003988	4Fe-4S binding domain; Region: Fer4; cl02805
1030843003989	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1030843003990	Domain of unknown function (DUF4248); Region: DUF4248; pfam14053
1030843003991	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1030843003992	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1030843003993	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1030843003994	catalytic residue [active]
1030843003995	Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]; Region: HemN; COG0635
1030843003996	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843003997	FeS/SAM binding site; other site
1030843003998	HemN C-terminal domain; Region: HemN_C; pfam06969
1030843003999	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1030843004000	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1030843004001	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1030843004002	active site
1030843004003	ATP-binding site [chemical binding]; other site
1030843004004	pantoate-binding site; other site
1030843004005	HXXH motif; other site
1030843004006	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1030843004007	active site
1030843004008	SAM binding site [chemical binding]; other site
1030843004009	homodimer interface [polypeptide binding]; other site
1030843004010	2-amino-3-ketobutyrate coenzyme A ligase; Provisional; Region: PRK06939
1030843004011	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1030843004012	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1030843004013	catalytic residue [active]
1030843004014	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1030843004015	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1030843004016	ATP-binding [chemical binding]; other site
1030843004017	CoA-binding site [chemical binding]; other site
1030843004018	YbbR-like protein; Region: YbbR; pfam07949
1030843004019	Preprotein translocase subunit; Region: YajC; pfam02699
1030843004020	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1030843004021	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1030843004022	DNA binding site [nucleotide binding]
1030843004023	active site
1030843004024	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1030843004025	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843004026	Walker A motif; other site
1030843004027	ATP binding site [chemical binding]; other site
1030843004028	Walker B motif; other site
1030843004029	arginine finger; other site
1030843004030	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1030843004031	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1030843004032	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1030843004033	Domain of unknown function (DUF389); Region: DUF389; pfam04087
1030843004034	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1030843004035	Peptidase S46; Region: Peptidase_S46; pfam10459
1030843004036	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1030843004037	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
1030843004038	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843004039	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1030843004040	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1030843004041	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1030843004042	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1030843004043	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1030843004044	Predicted permeases [General function prediction only]; Region: COG0795
1030843004045	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1030843004046	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1030843004047	SmpB-tmRNA interface; other site
1030843004048	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1030843004049	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1030843004050	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1030843004051	lipoyl synthase; Provisional; Region: PRK05481
1030843004052	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
1030843004053	FeS/SAM binding site; other site
1030843004054	Propeptide_C25; Region: Propeptide_C25; pfam08126
1030843004055	gingipain subgroup of the Peptidase C25 family N-terminal domain; Region: Peptidase_C25_N_gingipain; cd10913
1030843004056	active site
1030843004057	Peptidase family C25, C terminal ig-like domain; Region: Peptidase_C25_C; pfam03785
1030843004058	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843004059	HAD-superfamily subfamily IB hydrolase, TIGR01490; Region: HAD-SF-IB-hyp1
1030843004060	phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Provisional; Region: PRK12324
1030843004061	probable rRNA maturation factor YbeY; Region: TIGR00043
1030843004062	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
1030843004063	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
1030843004064	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1030843004065	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1030843004066	catalytic site [active]
1030843004067	G-X2-G-X-G-K; other site
1030843004068	hypothetical protein; Provisional; Region: PRK11820
1030843004069	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1030843004070	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1030843004071	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
1030843004072	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1030843004073	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843004074	nucleotide binding region [chemical binding]; other site
1030843004075	ATP-binding site [chemical binding]; other site
1030843004076	SEC-C motif; Region: SEC-C; pfam02810
1030843004077	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1030843004078	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
1030843004079	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1030843004080	CAAX protease self-immunity; Region: Abi; pfam02517
1030843004081	chaperonin GroL; Region: GroEL; TIGR02348
1030843004082	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1030843004083	ring oligomerisation interface [polypeptide binding]; other site
1030843004084	ATP/Mg binding site [chemical binding]; other site
1030843004085	stacking interactions; other site
1030843004086	hinge regions; other site
1030843004087	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1030843004088	oligomerisation interface [polypeptide binding]; other site
1030843004089	mobile loop; other site
1030843004090	roof hairpin; other site
1030843004091	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1030843004092	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1030843004093	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07107
1030843004094	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1030843004095	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH_2; cd04602
1030843004096	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1030843004097	active site
1030843004098	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843004099	CTP synthetase; Validated; Region: pyrG; PRK05380
1030843004100	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1030843004101	Catalytic site [active]
1030843004102	active site
1030843004103	UTP binding site [chemical binding]; other site
1030843004104	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1030843004105	active site
1030843004106	putative oxyanion hole; other site
1030843004107	catalytic triad [active]
1030843004108	membrane protein insertase; Provisional; Region: PRK01318
1030843004109	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1030843004110	amidophosphoribosyltransferase; Provisional; Region: PRK06781
1030843004111	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
1030843004112	active site
1030843004113	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1030843004114	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1030843004115	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1030843004116	catalytic site [active]
1030843004117	subunit interface [polypeptide binding]; other site
1030843004118	carbamoyl-phosphate synthase, large subunit; Region: CPSaseII_lrg; TIGR01369
1030843004119	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1030843004120	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1030843004121	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1030843004122	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1030843004123	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1030843004124	Methylglyoxal synthase-like domain found in pyr1 and URA1-like carbamoyl phosphate synthetases (CPS), including ammonia-dependent CPS Type I, and glutamine-dependent CPS Type III. These are multidomain proteins, in which MGS is the C-terminal domain; Region: MGS_CPS_I_III; cd01423
1030843004125	probable substrate binding site [chemical binding]; other site
1030843004126	NAD synthetase; Reviewed; Region: nadE; PRK02628
1030843004127	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
1030843004128	multimer interface [polypeptide binding]; other site
1030843004129	active site
1030843004130	catalytic triad [active]
1030843004131	protein interface 1 [polypeptide binding]; other site
1030843004132	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1030843004133	homodimer interface [polypeptide binding]; other site
1030843004134	NAD binding pocket [chemical binding]; other site
1030843004135	ATP binding pocket [chemical binding]; other site
1030843004136	Mg binding site [ion binding]; other site
1030843004137	active-site loop [active]
1030843004138	VanW like protein; Region: VanW; pfam04294
1030843004139	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843004140	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1030843004141	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843004142	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
1030843004143	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1030843004144	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1030843004145	metal binding site [ion binding]; metal-binding site
1030843004146	dimer interface [polypeptide binding]; other site
1030843004147	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1030843004148	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1030843004149	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1030843004150	HlyD family secretion protein; Region: HlyD_3; pfam13437
1030843004151	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1030843004152	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843004153	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843004154	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843004155	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843004156	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843004157	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843004158	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1030843004159	active site
1030843004160	DNA binding site [nucleotide binding]
1030843004161	Int/Topo IB signature motif; other site
1030843004162	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
1030843004163	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843004164	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843004165	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1030843004166	AAA domain; Region: AAA_14; pfam13173
1030843004167	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1030843004168	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1030843004169	dimer interface [polypeptide binding]; other site
1030843004170	PYR/PP interface [polypeptide binding]; other site
1030843004171	TPP binding site [chemical binding]; other site
1030843004172	substrate binding site [chemical binding]; other site
1030843004173	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1030843004174	Domain of unknown function; Region: EKR; smart00890
1030843004175	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1030843004176	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1030843004177	TPP-binding site [chemical binding]; other site
1030843004178	dimer interface [polypeptide binding]; other site
1030843004179	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843004180	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843004181	purine nucleoside phosphorylase I, inosine and guanosine-specific; Region: PNPH; TIGR01700
1030843004182	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1030843004183	N-ethylammeline chlorohydrolase; Provisional; Region: PRK06038
1030843004184	active site
1030843004185	putative substrate binding pocket [chemical binding]; other site
1030843004186	hypothetical protein; Validated; Region: PRK09104
1030843004187	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
1030843004188	metal binding site [ion binding]; metal-binding site
1030843004189	putative dimer interface [polypeptide binding]; other site
1030843004190	putative transporter; Validated; Region: PRK03818
1030843004191	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1030843004192	TrkA-C domain; Region: TrkA_C; pfam02080
1030843004193	TrkA-C domain; Region: TrkA_C; pfam02080
1030843004194	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1030843004195	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cl00251
1030843004196	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843004197	elongation factor P; Validated; Region: PRK00529
1030843004198	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1030843004199	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1030843004200	RNA binding site [nucleotide binding]; other site
1030843004201	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1030843004202	RNA binding site [nucleotide binding]; other site
1030843004203	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1030843004204	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1030843004205	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1030843004206	MraW methylase family; Region: Methyltransf_5; cl17771
1030843004207	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1030843004208	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1030843004209	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1030843004210	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1030843004211	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1030843004212	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1030843004213	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1030843004214	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1030843004215	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1030843004216	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1030843004217	Mg++ binding site [ion binding]; other site
1030843004218	putative catalytic motif [active]
1030843004219	putative substrate binding site [chemical binding]; other site
1030843004220	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
1030843004221	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1030843004222	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1030843004223	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1030843004224	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1030843004225	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1030843004226	active site
1030843004227	homodimer interface [polypeptide binding]; other site
1030843004228	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1030843004229	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1030843004230	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1030843004231	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1030843004232	Cell division protein FtsA; Region: FtsA; smart00842
1030843004233	Cell division protein FtsA; Region: FtsA; pfam14450
1030843004234	cell division protein FtsZ; Validated; Region: PRK09330
1030843004235	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1030843004236	nucleotide binding site [chemical binding]; other site
1030843004237	SulA interaction site; other site
1030843004238	Yqey-like protein; Region: YqeY; pfam09424
1030843004239	Predicted membrane protein [Function unknown]; Region: COG2860
1030843004240	UPF0126 domain; Region: UPF0126; pfam03458
1030843004241	UPF0126 domain; Region: UPF0126; pfam03458
1030843004242	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1030843004243	oligomerization interface [polypeptide binding]; other site
1030843004244	active site
1030843004245	metal binding site [ion binding]; metal-binding site
1030843004246	GMP synthase; Reviewed; Region: guaA; PRK00074
1030843004247	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1030843004248	AMP/PPi binding site [chemical binding]; other site
1030843004249	candidate oxyanion hole; other site
1030843004250	catalytic triad [active]
1030843004251	potential glutamine specificity residues [chemical binding]; other site
1030843004252	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1030843004253	ATP Binding subdomain [chemical binding]; other site
1030843004254	Ligand Binding sites [chemical binding]; other site
1030843004255	Dimerization subdomain; other site
1030843004256	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1030843004257	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1030843004258	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1030843004259	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1030843004260	protein binding site [polypeptide binding]; other site
1030843004261	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1030843004262	protein binding site [polypeptide binding]; other site
1030843004263	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1030843004264	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
1030843004265	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1030843004266	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1030843004267	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1030843004268	DNA binding residues [nucleotide binding]
1030843004269	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1030843004270	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1030843004271	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1030843004272	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1030843004273	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1030843004274	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1030843004275	Predicted permeases [General function prediction only]; Region: COG0795
1030843004276	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1030843004277	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1030843004278	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
1030843004279	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1030843004280	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1030843004281	dimerization interface [polypeptide binding]; other site
1030843004282	active site
1030843004283	cytidylate kinase; Provisional; Region: cmk; PRK00023
1030843004284	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1030843004285	active site
1030843004286	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1030843004287	CMP-binding site; other site
1030843004288	The sites determining sugar specificity; other site
1030843004289	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1030843004290	LytB protein; Region: LYTB; cl00507
1030843004291	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1030843004292	putative catalytic site [active]
1030843004293	putative metal binding site [ion binding]; other site
1030843004294	putative phosphate binding site [ion binding]; other site
1030843004295	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1030843004296	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cl03181
1030843004297	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843004298	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1030843004299	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
1030843004300	G1 box; other site
1030843004301	putative GEF interaction site [polypeptide binding]; other site
1030843004302	GTP/Mg2+ binding site [chemical binding]; other site
1030843004303	Switch I region; other site
1030843004304	G2 box; other site
1030843004305	G3 box; other site
1030843004306	Switch II region; other site
1030843004307	G4 box; other site
1030843004308	G5 box; other site
1030843004309	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1030843004310	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1030843004311	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1030843004312	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843004313	variable surface protein Vir12; Provisional; Region: PTZ00234
1030843004314	peroxiredoxin; Region: AhpC; TIGR03137
1030843004315	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1030843004316	dimer interface [polypeptide binding]; other site
1030843004317	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1030843004318	catalytic triad [active]
1030843004319	peroxidatic and resolving cysteines [active]
1030843004320	alkyl hydroperoxide reductase subunit F; Region: AhpF; TIGR03140
1030843004321	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1030843004322	catalytic residue [active]
1030843004323	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1030843004324	catalytic residues [active]
1030843004325	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1030843004326	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1030843004327	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1030843004328	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1030843004329	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843004330	Walker A motif; other site
1030843004331	ATP binding site [chemical binding]; other site
1030843004332	Walker B motif; other site
1030843004333	arginine finger; other site
1030843004334	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1030843004335	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
1030843004336	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
1030843004337	DoxX; Region: DoxX; pfam07681
1030843004338	triosephosphate isomerase; Provisional; Region: PRK14567
1030843004339	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1030843004340	substrate binding site [chemical binding]; other site
1030843004341	dimer interface [polypeptide binding]; other site
1030843004342	catalytic triad [active]
1030843004343	Sporulation related domain; Region: SPOR; pfam05036
1030843004344	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1030843004345	homodecamer interface [polypeptide binding]; other site
1030843004346	GTP cyclohydrolase I; Provisional; Region: PLN03044
1030843004347	active site
1030843004348	putative catalytic site residues [active]
1030843004349	zinc binding site [ion binding]; other site
1030843004350	GTP-CH-I/GFRP interaction surface; other site
1030843004351	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
1030843004352	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
1030843004353	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1030843004354	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1030843004355	Walker A/P-loop; other site
1030843004356	ATP binding site [chemical binding]; other site
1030843004357	Q-loop/lid; other site
1030843004358	ABC transporter signature motif; other site
1030843004359	Walker B; other site
1030843004360	D-loop; other site
1030843004361	H-loop/switch region; other site
1030843004362	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
1030843004363	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1030843004364	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1030843004365	active site
1030843004366	hydrophilic channel; other site
1030843004367	dimerization interface [polypeptide binding]; other site
1030843004368	catalytic residues [active]
1030843004369	active site lid [active]
1030843004370	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
1030843004371	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1030843004372	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1030843004373	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
1030843004374	DJ-1 family protein; Region: not_thiJ; TIGR01383
1030843004375	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1030843004376	conserved cys residue [active]
1030843004377	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
1030843004378	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1030843004379	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843004380	S-adenosylmethionine binding site [chemical binding]; other site
1030843004381	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_1; cd13140
1030843004382	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1030843004383	thiamine-monophosphate kinase; Region: thiL; TIGR01379
1030843004384	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1030843004385	ATP binding site [chemical binding]; other site
1030843004386	dimerization interface [polypeptide binding]; other site
1030843004387	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
1030843004388	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1030843004389	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1030843004390	tandem repeat interface [polypeptide binding]; other site
1030843004391	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1030843004392	oligomer interface [polypeptide binding]; other site
1030843004393	active site residues [active]
1030843004394	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1030843004395	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1030843004396	tandem repeat interface [polypeptide binding]; other site
1030843004397	oligomer interface [polypeptide binding]; other site
1030843004398	active site residues [active]
1030843004399	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1030843004400	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1030843004401	N-terminal plug; other site
1030843004402	ligand-binding site [chemical binding]; other site
1030843004403	Adenosylcobinamide amidohydrolase; Region: CbiZ; pfam01955
1030843004404	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1030843004405	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1030843004406	Walker A/P-loop; other site
1030843004407	ATP binding site [chemical binding]; other site
1030843004408	Q-loop/lid; other site
1030843004409	ABC transporter signature motif; other site
1030843004410	Walker B; other site
1030843004411	D-loop; other site
1030843004412	H-loop/switch region; other site
1030843004413	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1030843004414	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1030843004415	ABC-ATPase subunit  interface; other site
1030843004416	dimer interface [polypeptide binding]; other site
1030843004417	putative PBP binding regions; other site
1030843004418	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1030843004419	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1030843004420	intersubunit interface [polypeptide binding]; other site
1030843004421	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
1030843004422	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
1030843004423	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1030843004424	Zn2+ binding site [ion binding]; other site
1030843004425	Mg2+ binding site [ion binding]; other site
1030843004426	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
1030843004427	CT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_1; cd04870
1030843004428	ACT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_2; cd04871
1030843004429	phosphoserine phosphatase SerB; Region: serB; TIGR00338
1030843004430	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843004431	motif II; other site
1030843004432	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843004433	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1030843004434	Maf-like protein; Region: Maf; pfam02545
1030843004435	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1030843004436	active site
1030843004437	dimer interface [polypeptide binding]; other site
1030843004438	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1030843004439	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843004440	active site
1030843004441	motif I; other site
1030843004442	motif II; other site
1030843004443	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1030843004444	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
1030843004445	NAD(P)H:flavin oxidoreductase-like family 2.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_2; cd02151
1030843004446	putative FMN binding site [chemical binding]; other site
1030843004447	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1030843004448	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1030843004449	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1030843004450	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1030843004451	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1030843004452	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1030843004453	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1030843004454	Phosphotransferase enzyme family; Region: APH; pfam01636
1030843004455	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1030843004456	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843004457	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
1030843004458	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1030843004459	N-terminal plug; other site
1030843004460	ligand-binding site [chemical binding]; other site
1030843004461	Cobalt chelatase (CbiK); Region: CbiK; pfam06180
1030843004462	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1030843004463	active site
1030843004464	C-terminal domain interface [polypeptide binding]; other site
1030843004465	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1030843004466	active site
1030843004467	N-terminal domain interface [polypeptide binding]; other site
1030843004468	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1030843004469	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1030843004470	intersubunit interface [polypeptide binding]; other site
1030843004471	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1030843004472	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1030843004473	ABC-ATPase subunit  interface; other site
1030843004474	dimer interface [polypeptide binding]; other site
1030843004475	putative PBP binding regions; other site
1030843004476	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1030843004477	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1030843004478	Walker A/P-loop; other site
1030843004479	ATP binding site [chemical binding]; other site
1030843004480	Q-loop/lid; other site
1030843004481	ABC transporter signature motif; other site
1030843004482	Walker B; other site
1030843004483	D-loop; other site
1030843004484	H-loop/switch region; other site
1030843004485	indolepyruvate oxidoreductase subunit beta; Reviewed; Region: PRK06853
1030843004486	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
1030843004487	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1030843004488	dimer interface [polypeptide binding]; other site
1030843004489	PYR/PP interface [polypeptide binding]; other site
1030843004490	TPP binding site [chemical binding]; other site
1030843004491	substrate binding site [chemical binding]; other site
1030843004492	Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008
1030843004493	TPP-binding site; other site
1030843004494	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1030843004495	malonic semialdehyde reductase; Provisional; Region: PRK10538
1030843004496	putative NAD(P) binding site [chemical binding]; other site
1030843004497	homodimer interface [polypeptide binding]; other site
1030843004498	homotetramer interface [polypeptide binding]; other site
1030843004499	active site
1030843004500	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
1030843004501	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1030843004502	catalytic triad [active]
1030843004503	conserved cis-peptide bond; other site
1030843004504	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1030843004505	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1030843004506	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1030843004507	HlyD family secretion protein; Region: HlyD_3; pfam13437
1030843004508	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1030843004509	FtsX-like permease family; Region: FtsX; pfam02687
1030843004510	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1030843004511	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
1030843004512	FtsX-like permease family; Region: FtsX; pfam02687
1030843004513	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1030843004514	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
1030843004515	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1030843004516	FtsX-like permease family; Region: FtsX; pfam02687
1030843004517	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1030843004518	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1030843004519	Walker A/P-loop; other site
1030843004520	ATP binding site [chemical binding]; other site
1030843004521	Q-loop/lid; other site
1030843004522	ABC transporter signature motif; other site
1030843004523	Walker B; other site
1030843004524	D-loop; other site
1030843004525	H-loop/switch region; other site
1030843004526	Uncharacterized conserved protein [Function unknown]; Region: COG2461
1030843004527	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
1030843004528	Domain of unknown function (DUF1858); Region: DUF1858; cl14817
1030843004529	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1030843004530	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1030843004531	putative catalytic cysteine [active]
1030843004532	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1030843004533	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1030843004534	active site
1030843004535	NAD binding site [chemical binding]; other site
1030843004536	metal binding site [ion binding]; metal-binding site
1030843004537	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
1030843004538	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1030843004539	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1030843004540	NifU-like domain; Region: NifU; cl00484
1030843004541	Aromatic ring hydroxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2368
1030843004542	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1030843004543	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1030843004544	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1030843004545	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1030843004546	ligand binding site [chemical binding]; other site
1030843004547	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1030843004548	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1030843004549	ligand binding site [chemical binding]; other site
1030843004550	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1030843004551	This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important...; Region: GT1_Glycogen_Phosphorylase_like; cd04299
1030843004552	putative homodimer interface [polypeptide binding]; other site
1030843004553	putative active site pocket [active]
1030843004554	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
1030843004555	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1030843004556	homotrimer interface [polypeptide binding]; other site
1030843004557	Walker A motif; other site
1030843004558	GTP binding site [chemical binding]; other site
1030843004559	Walker B motif; other site
1030843004560	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1030843004561	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1030843004562	putative dimer interface [polypeptide binding]; other site
1030843004563	active site pocket [active]
1030843004564	putative cataytic base [active]
1030843004565	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1030843004566	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1030843004567	catalytic core [active]
1030843004568	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1030843004569	META domain; Region: META; pfam03724
1030843004570	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843004571	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1030843004572	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1030843004573	N-terminal plug; other site
1030843004574	ligand-binding site [chemical binding]; other site
1030843004575	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1030843004576	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1030843004577	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1030843004578	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1030843004579	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1030843004580	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1030843004581	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1030843004582	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1030843004583	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1030843004584	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1030843004585	PAS domain; Region: PAS_9; pfam13426
1030843004586	putative active site [active]
1030843004587	heme pocket [chemical binding]; other site
1030843004588	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1030843004589	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1030843004590	glutamine binding [chemical binding]; other site
1030843004591	catalytic triad [active]
1030843004592	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
1030843004593	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1030843004594	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1030843004595	Cl binding site [ion binding]; other site
1030843004596	oligomer interface [polypeptide binding]; other site
1030843004597	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1030843004598	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1030843004599	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1030843004600	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1030843004601	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1030843004602	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1030843004603	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1030843004604	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1030843004605	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1030843004606	dimer interface [polypeptide binding]; other site
1030843004607	phosphorylation site [posttranslational modification]
1030843004608	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843004609	ATP binding site [chemical binding]; other site
1030843004610	Mg2+ binding site [ion binding]; other site
1030843004611	G-X-G motif; other site
1030843004612	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1030843004613	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1030843004614	active site
1030843004615	phosphorylation site [posttranslational modification]
1030843004616	intermolecular recognition site; other site
1030843004617	dimerization interface [polypeptide binding]; other site
1030843004618	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1030843004619	DNA binding site [nucleotide binding]
1030843004620	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1030843004621	NlpC/P60 family; Region: NLPC_P60; pfam00877
1030843004622	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1030843004623	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1030843004624	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1030843004625	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1030843004626	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1030843004627	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1030843004628	PEGA domain; Region: PEGA; pfam08308
1030843004629	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1030843004630	putative acyl-acceptor binding pocket; other site
1030843004631	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1030843004632	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1030843004633	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1030843004634	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1030843004635	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1030843004636	RNA binding surface [nucleotide binding]; other site
1030843004637	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1030843004638	active site
1030843004639	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1030843004640	PASTA domain. This domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and...; Region: PASTA; cl02768
1030843004641	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1030843004642	Lumazine binding domain; Region: Lum_binding; pfam00677
1030843004643	Lumazine binding domain; Region: Lum_binding; pfam00677
1030843004644	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
1030843004645	putative FMN binding site [chemical binding]; other site
1030843004646	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1030843004647	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1030843004648	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1030843004649	catalytic residue [active]
1030843004650	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1030843004651	RNA/DNA hybrid binding site [nucleotide binding]; other site
1030843004652	active site
1030843004653	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1030843004654	nucleoside/Zn binding site; other site
1030843004655	dimer interface [polypeptide binding]; other site
1030843004656	catalytic motif [active]
1030843004657	ribonuclease Z; Region: RNase_Z; TIGR02651
1030843004658	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1030843004659	NlpC/P60 family; Region: NLPC_P60; pfam00877
1030843004660	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1030843004661	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1030843004662	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1030843004663	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1030843004664	dimer interface [polypeptide binding]; other site
1030843004665	active site
1030843004666	metal binding site [ion binding]; metal-binding site
1030843004667	glutathione binding site [chemical binding]; other site
1030843004668	PAS domain; Region: PAS; smart00091
1030843004669	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1030843004670	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843004671	ATP binding site [chemical binding]; other site
1030843004672	Mg2+ binding site [ion binding]; other site
1030843004673	G-X-G motif; other site
1030843004674	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1030843004675	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1030843004676	active site
1030843004677	phosphorylation site [posttranslational modification]
1030843004678	intermolecular recognition site; other site
1030843004679	dimerization interface [polypeptide binding]; other site
1030843004680	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843004681	Walker A motif; other site
1030843004682	ATP binding site [chemical binding]; other site
1030843004683	Walker B motif; other site
1030843004684	arginine finger; other site
1030843004685	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1030843004686	metal-binding site
1030843004687	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1030843004688	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1030843004689	active site
1030843004690	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1030843004691	Peptidase family U32; Region: Peptidase_U32; pfam01136
1030843004692	Collagenase; Region: DUF3656; pfam12392
1030843004693	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843004694	DNA topoisomerase I; Validated; Region: PRK06599
1030843004695	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1030843004696	active site
1030843004697	interdomain interaction site; other site
1030843004698	putative metal-binding site [ion binding]; other site
1030843004699	nucleotide binding site [chemical binding]; other site
1030843004700	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1030843004701	domain I; other site
1030843004702	DNA binding groove [nucleotide binding]
1030843004703	phosphate binding site [ion binding]; other site
1030843004704	domain II; other site
1030843004705	domain III; other site
1030843004706	nucleotide binding site [chemical binding]; other site
1030843004707	catalytic site [active]
1030843004708	domain IV; other site
1030843004709	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1030843004710	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1030843004711	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1030843004712	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1030843004713	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1030843004714	dimerization interface 3.5A [polypeptide binding]; other site
1030843004715	active site
1030843004716	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843004717	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
1030843004718	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
1030843004719	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1030843004720	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1030843004721	active site
1030843004722	Zn binding site [ion binding]; other site
1030843004723	TPR repeat; Region: TPR_11; pfam13414
1030843004724	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843004725	binding surface
1030843004726	TPR motif; other site
1030843004727	trigger factor; Region: tig; TIGR00115
1030843004728	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1030843004729	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1030843004730	RNase E interface [polypeptide binding]; other site
1030843004731	trimer interface [polypeptide binding]; other site
1030843004732	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1030843004733	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1030843004734	RNase E interface [polypeptide binding]; other site
1030843004735	trimer interface [polypeptide binding]; other site
1030843004736	active site
1030843004737	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1030843004738	putative nucleic acid binding region [nucleotide binding]; other site
1030843004739	G-X-X-G motif; other site
1030843004740	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1030843004741	RNA binding site [nucleotide binding]; other site
1030843004742	domain interface; other site
1030843004743	4-alpha-glucanotransferase; Region: PLN02950
1030843004744	The family 20 carbohydrate-binding module (CBM20), also known as the starch-binding domain, is found in a large number of starch degrading enzymes including alpha-amylase, beta-amylase, glucoamylase, and CGTase (cyclodextrin glucanotransferase). CBM20 is...; Region: CBM20; cl15347
1030843004745	starch-binding site 2 [chemical binding]; other site
1030843004746	The family 20 carbohydrate-binding module (CBM20), also known as the starch-binding domain, is found in a large number of starch degrading enzymes including alpha-amylase, beta-amylase, glucoamylase, and CGTase (cyclodextrin glucanotransferase). CBM20 is...; Region: CBM20; cl15347
1030843004747	starch-binding site 2 [chemical binding]; other site
1030843004748	starch-binding site 1 [chemical binding]; other site
1030843004749	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
1030843004750	Protein of unknown function (DUF2891); Region: DUF2891; pfam11199
1030843004751	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1030843004752	Putative acyl-CoA dehydrogenases similar to fadE5; Region: ACAD_fadE5; cd01153
1030843004753	FAD binding site [chemical binding]; other site
1030843004754	substrate binding site [chemical binding]; other site
1030843004755	catalytic residues [active]
1030843004756	Acyl-CoA dehydrogenase C terminal; Region: AcylCoA_dehyd_C; pfam12186
1030843004757	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1030843004758	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1030843004759	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1030843004760	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1030843004761	Ligand binding site [chemical binding]; other site
1030843004762	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1030843004763	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1030843004764	Glycoprotease family; Region: Peptidase_M22; pfam00814
1030843004765	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1030843004766	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1030843004767	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1030843004768	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
1030843004769	Amidohydrolase; Region: Amidohydro_4; pfam13147
1030843004770	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1030843004771	active site
1030843004772	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1030843004773	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1030843004774	substrate binding pocket [chemical binding]; other site
1030843004775	chain length determination region; other site
1030843004776	substrate-Mg2+ binding site; other site
1030843004777	catalytic residues [active]
1030843004778	aspartate-rich region 1; other site
1030843004779	active site lid residues [active]
1030843004780	aspartate-rich region 2; other site
1030843004781	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1030843004782	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1030843004783	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843004784	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1030843004785	B3/4 domain; Region: B3_4; pfam03483
1030843004786	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1030843004787	GTP1/OBG; Region: GTP1_OBG; pfam01018
1030843004788	Obg GTPase; Region: Obg; cd01898
1030843004789	G1 box; other site
1030843004790	GTP/Mg2+ binding site [chemical binding]; other site
1030843004791	Switch I region; other site
1030843004792	G2 box; other site
1030843004793	G3 box; other site
1030843004794	Switch II region; other site
1030843004795	G4 box; other site
1030843004796	G5 box; other site
1030843004797	adenylate kinase; Reviewed; Region: adk; PRK00279
1030843004798	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1030843004799	AMP-binding site [chemical binding]; other site
1030843004800	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1030843004801	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1030843004802	active site
1030843004803	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
1030843004804	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
1030843004805	Transglycosylase; Region: Transgly; pfam00912
1030843004806	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1030843004807	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1030843004808	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1030843004809	leucyl-tRNA synthetase, eubacterial and mitochondrial family; Region: leuS_bact; TIGR00396
1030843004810	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1030843004811	HIGH motif; other site
1030843004812	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1030843004813	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1030843004814	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1030843004815	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1030843004816	active site
1030843004817	KMSKS motif; other site
1030843004818	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1030843004819	tRNA binding surface [nucleotide binding]; other site
1030843004820	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
1030843004821	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1030843004822	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
1030843004823	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1030843004824	active site
1030843004825	NTP binding site [chemical binding]; other site
1030843004826	metal binding triad [ion binding]; metal-binding site
1030843004827	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1030843004828	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1030843004829	Zn2+ binding site [ion binding]; other site
1030843004830	Mg2+ binding site [ion binding]; other site
1030843004831	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1030843004832	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
1030843004833	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1030843004834	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1030843004835	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1030843004836	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1030843004837	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1030843004838	active site
1030843004839	trimer interface [polypeptide binding]; other site
1030843004840	allosteric site; other site
1030843004841	active site lid [active]
1030843004842	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1030843004843	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1030843004844	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1030843004845	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1030843004846	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1030843004847	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
1030843004848	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1030843004849	putative RNA binding site [nucleotide binding]; other site
1030843004850	transcription antitermination factor NusB; Region: nusB; TIGR01951
1030843004851	cell surface protein SprA; Region: surface_SprA; TIGR04189
1030843004852	Motility related/secretion protein; Region: SprA_N; pfam14349
1030843004853	Motility related/secretion protein; Region: SprA_N; pfam14349
1030843004854	Motility related/secretion protein; Region: SprA_N; pfam14349
1030843004855	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1030843004856	RuvA N terminal domain; Region: RuvA_N; pfam01330
1030843004857	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1030843004858	partial transposase in ISPg1; similar to RefSeq{20100916}, gi|188994872|ref|YP_001929124.1| partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277]|, percent identity 97 in 230 aa, BLASTP E(): 1e-130
1030843004859	partial ROK family transcriptional repressor with glucose kinase domain; similar to nr, gi|188994244|ref|YP_001928496.1| partial ROK family transcriptional repressor with glucose kinase domain [Porphyromonas gingivalis ATCC 33277] partial ROK family transcriptional repressor with glucose kinase domain [Porphyromonas gingivalis ATCC 33277], percent identity 90 in 30 aa, BLASTP E(): 7e-8
1030843004860	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843004861	partial transposase in ISPg2; similar to RefSeq{20100916}, gi|34540119|ref|NP_904598.1| ISPg2, transposase [Porphyromonas gingivalis W83]|, percent identity 98.9 in 190 aa, BLASTP E(): 1e-109
1030843004862	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843004863	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843004864	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843004865	partial transposase in ISPg2; similar to RefSeq{20100916}, gi|188995258|ref|YP_001929510.1| transposase in ISPg2 [Porphyromonas gingivalis ATCC 33277]|, percent identity 99.2 in 130 aa, BLASTP E(): 3e-69
1030843004866	AAA domain; Region: AAA_13; pfam13166
1030843004867	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843004868	ABC transporter signature motif; other site
1030843004869	Walker B; other site
1030843004870	D-loop; other site
1030843004871	H-loop/switch region; other site
1030843004872	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1030843004873	potential frameshift: common BLAST hit: gi|257064729|ref|YP_003144401.1| type I restriction-modification system methyltransferase subunit
1030843004874	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1030843004875	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
1030843004876	Protein of unknown function (DUF3853); Region: DUF3853; pfam12964
1030843004877	AAA domain; Region: AAA_25; pfam13481
1030843004878	CHC2 zinc finger; Region: zf-CHC2; cl17510
1030843004879	Toprim-like; Region: Toprim_2; pfam13155
1030843004880	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
1030843004881	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
1030843004882	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1030843004883	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1030843004884	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1030843004885	active site
1030843004886	DNA binding site [nucleotide binding]
1030843004887	Int/Topo IB signature motif; other site
1030843004888	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
1030843004889	Int/Topo IB signature motif; other site
1030843004890	Domain of unknown function (DUF1896); Region: DUF1896; pfam08989
1030843004891	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843004892	Helix-turn-helix domain; Region: HTH_17; pfam12728
1030843004893	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
1030843004894	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1030843004895	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1030843004896	active site
1030843004897	DNA binding site [nucleotide binding]
1030843004898	Int/Topo IB signature motif; other site
1030843004899	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1030843004900	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1030843004901	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1030843004902	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1030843004903	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1030843004904	Fic/DOC family; Region: Fic; cl00960
1030843004905	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1030843004906	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1030843004907	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1030843004908	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1030843004909	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1030843004910	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1030843004911	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1030843004912	ATP binding site [chemical binding]; other site
1030843004913	putative Mg++ binding site [ion binding]; other site
1030843004914	EcoEI R protein C-terminal; Region: EcoEI_R_C; pfam08463
1030843004915	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1030843004916	non-specific DNA binding site [nucleotide binding]; other site
1030843004917	salt bridge; other site
1030843004918	sequence-specific DNA binding site [nucleotide binding]; other site
1030843004919	potential frameshift: common BLAST hit: gi|327314381|ref|YP_004329818.1| helicase C-terminal domain-containing protein
1030843004920	Protein of unknown function (DUF2958); Region: DUF2958; pfam11171
1030843004921	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
1030843004922	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
1030843004923	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843004924	S-adenosylmethionine binding site [chemical binding]; other site
1030843004925	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
1030843004926	MutS domain I; Region: MutS_I; pfam01624
1030843004927	DNA topoisomerase III; Provisional; Region: PRK07726
1030843004928	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1030843004929	active site
1030843004930	putative interdomain interaction site [polypeptide binding]; other site
1030843004931	putative metal-binding site [ion binding]; other site
1030843004932	putative nucleotide binding site [chemical binding]; other site
1030843004933	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1030843004934	domain I; other site
1030843004935	DNA binding groove [nucleotide binding]
1030843004936	phosphate binding site [ion binding]; other site
1030843004937	domain II; other site
1030843004938	domain III; other site
1030843004939	nucleotide binding site [chemical binding]; other site
1030843004940	catalytic site [active]
1030843004941	domain IV; other site
1030843004942	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
1030843004943	Protein of unknown function (DUF4099); Region: DUF4099; pfam13351
1030843004944	Protein of unknown function (DUF3945); Region: DUF3945; pfam13101
1030843004945	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
1030843004946	ATP-GRASP peptide maturase, grasp-with-spasm system; Region: GRASP_w_spasm; TIGR04192
1030843004947	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
1030843004948	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843004949	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1030843004950	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
1030843004951	putative active site [active]
1030843004952	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1030843004953	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843004954	Walker A/P-loop; other site
1030843004955	ATP binding site [chemical binding]; other site
1030843004956	Q-loop/lid; other site
1030843004957	ABC transporter signature motif; other site
1030843004958	Walker B; other site
1030843004959	D-loop; other site
1030843004960	H-loop/switch region; other site
1030843004961	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843004962	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843004963	radical SAM/SPASM domain Clo7bot peptide maturase; Region: rSAM_Clo7bot; TIGR04334
1030843004964	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843004965	FeS/SAM binding site; other site
1030843004966	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1030843004967	LytTr DNA-binding domain; Region: LytTR; cl04498
1030843004968	partial transposase in ISPg6; similar to nr, gi|34540798|ref|NP_905277.1| ISPg6, transposase [Porphyromonas gingivalis W83] ISPg6, transposase [Porphyromonas gingivalis W83], percent identity 83.3 in 42 aa, BLASTP E(): 8e-12
1030843004969	partial transposase in ISPg6; similar to RefSeq{20100916}, gi|34540798|ref|NP_905277.1| ISPg6, transposase [Porphyromonas gingivalis W83]|, percent identity 70.1 in 87 aa, BLASTP E(): 2e-28
1030843004970	partial transposase in ISPg6; similar to nr, gi|229495145|ref|ZP_04388886.1| ISPg6, transposase [Porphyromonas endodontalis ATCC 35406] ISPg6, transposase [Porphyromonas endodontalis ATCC 35406], percent identity 92.3 in 52 aa, BLASTP E(): 5e-19
1030843004971	YWFCY protein; Region: YWFCY; pfam14293
1030843004972	AAA-like domain; Region: AAA_10; pfam12846
1030843004973	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1030843004974	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
1030843004975	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1030843004976	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1030843004977	Protein of unknown function (DUF3408); Region: DUF3408; pfam11888
1030843004978	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
1030843004979	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
1030843004980	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
1030843004981	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
1030843004982	Domain of unknown function (DUF4141); Region: DUF4141; pfam13605
1030843004983	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
1030843004984	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
1030843004985	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
1030843004986	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
1030843004987	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
1030843004988	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
1030843004989	Conjugative transposon protein TraO; Region: TraO; pfam10626
1030843004990	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
1030843004991	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843004992	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843004993	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843004994	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1030843004995	Uncharacterized protein conserved in bacteria (DUF2237); Region: DUF2237; cl01467
1030843004996	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843004997	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1030843004998	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843004999	Domain of unknown function, B. Theta Gene description (DUF3872); Region: DUF3872; pfam12988
1030843005000	Bacterial PH domain; Region: DUF304; cl01348
1030843005001	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843005002	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843005003	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843005004	S-adenosylmethionine binding site [chemical binding]; other site
1030843005005	Phospholipid methyltransferase; Region: PEMT; pfam04191
1030843005006	Domain of unknown function (DUF1896); Region: DUF1896; pfam08989
1030843005007	ORF6N domain; Region: ORF6N; pfam10543
1030843005008	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
1030843005009	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1030843005010	Int/Topo IB signature motif; other site
1030843005011	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1030843005012	substrate binding site; other site
1030843005013	dimer interface; other site
1030843005014	Exonuclease VII small subunit; Region: Exonuc_VII_S; pfam02609
1030843005015	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843005016	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005017	binding surface
1030843005018	TPR motif; other site
1030843005019	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843005020	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843005021	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005022	binding surface
1030843005023	TPR motif; other site
1030843005024	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1030843005025	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1030843005026	ATP binding site [chemical binding]; other site
1030843005027	Mg2+ binding site [ion binding]; other site
1030843005028	G-X-G motif; other site
1030843005029	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1030843005030	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1030843005031	active site
1030843005032	phosphorylation site [posttranslational modification]
1030843005033	intermolecular recognition site; other site
1030843005034	dimerization interface [polypeptide binding]; other site
1030843005035	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1030843005036	DNA binding residues [nucleotide binding]
1030843005037	dimerization interface [polypeptide binding]; other site
1030843005038	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1030843005039	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005040	TPR motif; other site
1030843005041	binding surface
1030843005042	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843005043	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1030843005044	homopentamer interface [polypeptide binding]; other site
1030843005045	active site
1030843005046	Peptidase C10 family; Region: Peptidase_C10; pfam01640
1030843005047	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843005048	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
1030843005049	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1030843005050	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843005051	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
1030843005052	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1030843005053	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1030843005054	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14971
1030843005055	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1030843005056	Walker A motif; other site
1030843005057	ATP binding site [chemical binding]; other site
1030843005058	Walker B motif; other site
1030843005059	arginine finger; other site
1030843005060	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1030843005061	fumarate hydratase; Provisional; Region: PRK15389
1030843005062	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1030843005063	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1030843005064	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1030843005065	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1030843005066	FMN binding site [chemical binding]; other site
1030843005067	substrate binding site [chemical binding]; other site
1030843005068	putative catalytic residue [active]
1030843005069	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843005070	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1030843005071	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843005072	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1030843005073	putative transporter; Validated; Region: PRK03818
1030843005074	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1030843005075	TrkA-C domain; Region: TrkA_C; pfam02080
1030843005076	TrkA-C domain; Region: TrkA_C; pfam02080
1030843005077	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1030843005078	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
1030843005079	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1030843005080	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; pfam12900
1030843005081	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1030843005082	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1030843005083	Rhomboid family; Region: Rhomboid; pfam01694
1030843005084	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
1030843005085	putative catalytic site [active]
1030843005086	putative metal binding site [ion binding]; other site
1030843005087	putative phosphate binding site [ion binding]; other site
1030843005088	tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; Region: tnaA; PRK13238
1030843005089	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
1030843005090	substrate binding site [chemical binding]; other site
1030843005091	tetramer interface [polypeptide binding]; other site
1030843005092	catalytic residue [active]
1030843005093	partial transposase in ISPg1; similar to RefSeq{20100916}, gi|188994831|ref|YP_001929083.1| partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277]|, percent identity 98.7 in 78 aa, BLASTP E(): 6e-39
1030843005094	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843005095	Transposase domain (DUF772); Region: DUF772; pfam05598
1030843005096	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1030843005097	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1030843005098	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1030843005099	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1030843005100	purine monophosphate binding site [chemical binding]; other site
1030843005101	dimer interface [polypeptide binding]; other site
1030843005102	putative catalytic residues [active]
1030843005103	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1030843005104	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1030843005105	rod shape-determining protein MreB; Provisional; Region: PRK13927
1030843005106	MreB and similar proteins; Region: MreB_like; cd10225
1030843005107	nucleotide binding site [chemical binding]; other site
1030843005108	Mg binding site [ion binding]; other site
1030843005109	putative protofilament interaction site [polypeptide binding]; other site
1030843005110	RodZ interaction site [polypeptide binding]; other site
1030843005111	rod shape-determining protein MreC; Provisional; Region: PRK13922
1030843005112	rod shape-determining protein MreC; Region: MreC; pfam04085
1030843005113	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
1030843005114	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1030843005115	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1030843005116	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1030843005117	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1030843005118	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1030843005119	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843005120	Protein of unknown function (DUF3256); Region: DUF3256; pfam11644
1030843005121	Striatin family; Region: Striatin; pfam08232
1030843005122	DNA gyrase subunit A; Validated; Region: PRK05560
1030843005123	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1030843005124	CAP-like domain; other site
1030843005125	active site
1030843005126	primary dimer interface [polypeptide binding]; other site
1030843005127	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1030843005128	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1030843005129	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1030843005130	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1030843005131	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1030843005132	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1030843005133	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005134	TPR motif; other site
1030843005135	binding surface
1030843005136	TPR repeat; Region: TPR_11; pfam13414
1030843005137	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005138	binding surface
1030843005139	TPR motif; other site
1030843005140	TPR repeat; Region: TPR_11; pfam13414
1030843005141	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1030843005142	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1030843005143	non-specific DNA binding site [nucleotide binding]; other site
1030843005144	salt bridge; other site
1030843005145	sequence-specific DNA binding site [nucleotide binding]; other site
1030843005146	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1030843005147	ATP binding site [chemical binding]; other site
1030843005148	putative Mg++ binding site [ion binding]; other site
1030843005149	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1030843005150	nucleotide binding region [chemical binding]; other site
1030843005151	ATP-binding site [chemical binding]; other site
1030843005152	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
1030843005153	Divergent AAA domain; Region: AAA_4; pfam04326
1030843005154	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1030843005155	HTH domain; Region: HTH_11; pfam08279
1030843005156	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1030843005157	DNA methylase; Region: N6_N4_Mtase; pfam01555
1030843005158	DNA methylase; Region: N6_N4_Mtase; pfam01555
1030843005159	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1030843005160	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1030843005161	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1030843005162	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
1030843005163	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1030843005164	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
1030843005165	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1030843005166	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1030843005167	dimer interface [polypeptide binding]; other site
1030843005168	conserved gate region; other site
1030843005169	putative PBP binding loops; other site
1030843005170	ABC-ATPase subunit interface; other site
1030843005171	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1030843005172	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1030843005173	Walker A/P-loop; other site
1030843005174	ATP binding site [chemical binding]; other site
1030843005175	Q-loop/lid; other site
1030843005176	ABC transporter signature motif; other site
1030843005177	Walker B; other site
1030843005178	D-loop; other site
1030843005179	H-loop/switch region; other site
1030843005180	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1030843005181	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1030843005182	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1030843005183	A/G-specific adenine glycosylase; Region: mutY; TIGR01084
1030843005184	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1030843005185	minor groove reading motif; other site
1030843005186	helix-hairpin-helix signature motif; other site
1030843005187	substrate binding pocket [chemical binding]; other site
1030843005188	active site
1030843005189	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1030843005190	DNA binding and oxoG recognition site [nucleotide binding]
1030843005191	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1030843005192	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843005193	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005194	TPR motif; other site
1030843005195	binding surface
1030843005196	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1030843005197	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1030843005198	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
1030843005199	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1030843005200	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1030843005201	dimer interface [polypeptide binding]; other site
1030843005202	putative anticodon binding site; other site
1030843005203	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1030843005204	motif 1; other site
1030843005205	active site
1030843005206	motif 2; other site
1030843005207	motif 3; other site
1030843005208	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
1030843005209	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1030843005210	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1030843005211	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1030843005212	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1030843005213	active site
1030843005214	dimer interface [polypeptide binding]; other site
1030843005215	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1030843005216	dimer interface [polypeptide binding]; other site
1030843005217	active site
1030843005218	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
1030843005219	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1030843005220	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1030843005221	hinge; other site
1030843005222	active site
1030843005223	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1030843005224	RimM N-terminal domain; Region: RimM; pfam01782
1030843005225	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1030843005226	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1030843005227	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1030843005228	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1030843005229	Homologues of TraJ from Bacteroides conjugative transposon; Region: CtnDOT_TraJ; pfam07863
1030843005230	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1030843005231	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1030843005232	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1030843005233	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1030843005234	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1030843005235	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1030843005236	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1030843005237	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1030843005238	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1030843005239	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1030843005240	potential frameshift: common BLAST hit: gi|34541044|ref|NP_905523.1| acetyltransferase
1030843005241	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1030843005242	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1030843005243	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1030843005244	Predicted membrane protein [Function unknown]; Region: COG4905
1030843005245	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Region: LPLAT_ABO13168-like; cd07988
1030843005246	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1030843005247	putative acyl-acceptor binding pocket; other site
1030843005248	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1030843005249	C-N hydrolase family amidase; Provisional; Region: PRK10438
1030843005250	putative active site [active]
1030843005251	catalytic triad [active]
1030843005252	dimer interface [polypeptide binding]; other site
1030843005253	multimer interface [polypeptide binding]; other site
1030843005254	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1030843005255	active site
1030843005256	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1030843005257	hydrophobic ligand binding site; other site
1030843005258	partial transposase in ISPg3; similar to nr, gi|188993971|ref|YP_001928223.1| partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg3 [Porphyromonas gingivalis ATCC 33277], percent identity 73.5 in 34 aa, BLASTP E(): 1e-5
1030843005259	partial transposase in ISPg1; similar to nr, gi|188994872|ref|YP_001929124.1| partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277] partial transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277], percent identity 95.9 in 49 aa, BLASTP E(): 1e-20
1030843005260	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
1030843005261	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1030843005262	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
1030843005263	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1030843005264	This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis; Region: GT1_wcfI_like; cd03825
1030843005265	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1030843005266	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1030843005267	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1030843005268	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1030843005269	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1030843005270	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1030843005271	FAD binding domain; Region: FAD_binding_4; pfam01565
1030843005272	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1030843005273	Sporulation related domain; Region: SPOR; pfam05036
1030843005274	L-lactate permease; Region: Lactate_perm; cl00701
1030843005275	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1030843005276	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1030843005277	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1030843005278	active site
1030843005279	DNA binding site [nucleotide binding]
1030843005280	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1030843005281	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1030843005282	Catalytic site [active]
1030843005283	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1030843005284	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1030843005285	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1030843005286	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1030843005287	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
1030843005288	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; cl00566
1030843005289	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1030843005290	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1030843005291	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
1030843005292	ligand binding site [chemical binding]; other site
1030843005293	homodimer interface [polypeptide binding]; other site
1030843005294	NAD(P) binding site [chemical binding]; other site
1030843005295	trimer interface B [polypeptide binding]; other site
1030843005296	trimer interface A [polypeptide binding]; other site
1030843005297	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
1030843005298	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1030843005299	partial transposase in ISPg5; similar to nr, gi|34539888|ref|NP_904367.1| ISPg5 transposase Orf2 [Porphyromonas gingivalis W83] ISPg5, transposase Orf2 [Porphyromonas gingivalis W83] ISPg5 transposase Orf2 [Porphyromonas gingivalis W83] ISPg5, transposase Orf2 [Porphyromonas gingivalis W83], percent identity 69.7 in 33 aa, BLASTP E(): 4e-6
1030843005300	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1030843005301	CoA binding domain; Region: CoA_binding_2; pfam13380
1030843005302	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1030843005303	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1030843005304	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1030843005305	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843005306	homodimer interface [polypeptide binding]; other site
1030843005307	catalytic residue [active]
1030843005308	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
1030843005309	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1030843005310	active site
1030843005311	putative DNA-binding cleft [nucleotide binding]; other site
1030843005312	dimer interface [polypeptide binding]; other site
1030843005313	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
1030843005314	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
1030843005315	putative active site [active]
1030843005316	PhoH-like protein; Region: PhoH; pfam02562
1030843005317	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
1030843005318	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
1030843005319	Potassium binding sites [ion binding]; other site
1030843005320	Cesium cation binding sites [ion binding]; other site
1030843005321	partial transposase in ISPg1; similar to RefSeq{20100916}, gi|188995483|ref|YP_001929735.1| transposase in ISPg1 [Porphyromonas gingivalis ATCC 33277]|, percent identity 96.3 in 160 aa, BLASTP E(): 3e-84
1030843005322	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1030843005323	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1030843005324	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1030843005325	DNA binding residues [nucleotide binding]
1030843005326	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
1030843005327	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1030843005328	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1030843005329	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1030843005330	Tetramer interface [polypeptide binding]; other site
1030843005331	active site
1030843005332	FMN-binding site [chemical binding]; other site
1030843005333	Peptidase family C69; Region: Peptidase_C69; cl17793
1030843005334	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
1030843005335	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
1030843005336	putative active site [active]
1030843005337	putative metal binding site [ion binding]; other site
1030843005338	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1030843005339	active site
1030843005340	metal binding site [ion binding]; metal-binding site
1030843005341	homotetramer interface [polypeptide binding]; other site
1030843005342	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1030843005343	Ligand Binding Site [chemical binding]; other site
1030843005344	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1030843005345	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1030843005346	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
1030843005347	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843005348	S-adenosylmethionine binding site [chemical binding]; other site
1030843005349	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1030843005350	glycine dehydrogenase; Provisional; Region: PRK05367
1030843005351	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1030843005352	tetramer interface [polypeptide binding]; other site
1030843005353	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843005354	catalytic residue [active]
1030843005355	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1030843005356	tetramer interface [polypeptide binding]; other site
1030843005357	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843005358	catalytic residue [active]
1030843005359	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
1030843005360	AAA domain; Region: AAA_30; pfam13604
1030843005361	Family description; Region: UvrD_C_2; pfam13538
1030843005362	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
1030843005363	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
1030843005364	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1030843005365	S-adenosylmethionine binding site [chemical binding]; other site
1030843005366	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1030843005367	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1030843005368	RNA binding site [nucleotide binding]; other site
1030843005369	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1030843005370	RNA binding site [nucleotide binding]; other site
1030843005371	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1030843005372	RNA binding site [nucleotide binding]; other site
1030843005373	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1030843005374	RNA binding site [nucleotide binding]; other site
1030843005375	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1030843005376	RNA binding site [nucleotide binding]; other site
1030843005377	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1030843005378	RNA binding site [nucleotide binding]; other site
1030843005379	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843005380	FeoA domain; Region: FeoA; pfam04023
1030843005381	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1030843005382	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1030843005383	G1 box; other site
1030843005384	GTP/Mg2+ binding site [chemical binding]; other site
1030843005385	Switch I region; other site
1030843005386	G2 box; other site
1030843005387	G3 box; other site
1030843005388	Switch II region; other site
1030843005389	G4 box; other site
1030843005390	G5 box; other site
1030843005391	Nucleoside recognition; Region: Gate; pfam07670
1030843005392	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1030843005393	Nucleoside recognition; Region: Gate; pfam07670
1030843005394	Putative catalytic domain, repeat 1, of uncharacterized hypothetical proteins similar to Nuc, an endonuclease from Salmonella typhimurium; Region: PLDc_Nuc_like_unchar1_1; cd09172
1030843005395	PLD-like domain; Region: PLDc_2; pfam13091
1030843005396	putative active site [active]
1030843005397	catalytic site [active]
1030843005398	Putative catalytic domain, repeat 2, of uncharacterized hypothetical proteins similar to Nuc, an endonuclease from Salmonella typhimurium; Region: PLDc_Nuc_like_unchar1_2; cd09173
1030843005399	PLD-like domain; Region: PLDc_2; pfam13091
1030843005400	putative active site [active]
1030843005401	catalytic site [active]
1030843005402	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1030843005403	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1030843005404	homodimer interface [polypeptide binding]; other site
1030843005405	substrate-cofactor binding pocket; other site
1030843005406	catalytic residue [active]
1030843005407	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1030843005408	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1030843005409	NADP binding site [chemical binding]; other site
1030843005410	active site
1030843005411	putative substrate binding site [chemical binding]; other site
1030843005412	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1030843005413	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1030843005414	NADP-binding site; other site
1030843005415	homotetramer interface [polypeptide binding]; other site
1030843005416	substrate binding site [chemical binding]; other site
1030843005417	homodimer interface [polypeptide binding]; other site
1030843005418	active site
1030843005419	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1030843005420	Ferritin-like domain; Region: Ferritin; pfam00210
1030843005421	ferroxidase diiron center [ion binding]; other site
1030843005422	glucosamine-6-phosphate deaminase-like protein; Validated; Region: PRK02122
1030843005423	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1030843005424	active site
1030843005425	trimer interface [polypeptide binding]; other site
1030843005426	allosteric site; other site
1030843005427	active site lid [active]
1030843005428	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1030843005429	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
1030843005430	Peptidase S46; Region: Peptidase_S46; pfam10459
1030843005431	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1030843005432	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
1030843005433	putative active site [active]
1030843005434	putative metal binding residues [ion binding]; other site
1030843005435	signature motif; other site
1030843005436	putative dimer interface [polypeptide binding]; other site
1030843005437	putative phosphate binding site [ion binding]; other site
1030843005438	Domain of unknown function (DUF2027); Region: DUF2027; pfam09640
1030843005439	Smr domain; Region: Smr; cl02619
1030843005440	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
1030843005441	Uncharacterized conserved protein [Function unknown]; Region: COG4198
1030843005442	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1030843005443	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
1030843005444	putative ligand binding site [chemical binding]; other site
1030843005445	putative NAD binding site [chemical binding]; other site
1030843005446	putative catalytic site [active]
1030843005447	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
1030843005448	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1030843005449	catalytic residue [active]
1030843005450	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
1030843005451	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1030843005452	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1030843005453	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1030843005454	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1030843005455	elongation factor P; Validated; Region: PRK00529
1030843005456	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1030843005457	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1030843005458	RNA binding site [nucleotide binding]; other site
1030843005459	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1030843005460	RNA binding site [nucleotide binding]; other site
1030843005461	ornithine aminotransferase; Region: Orn_aminotrans; TIGR01885
1030843005462	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1030843005463	inhibitor-cofactor binding pocket; inhibition site
1030843005464	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1030843005465	catalytic residue [active]
1030843005466	Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown]; Region: COG4874
1030843005467	Amidinotransferase; Region: Amidinotransf; pfam02274
1030843005468	Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; Region: ALDH_F4-17_P5CDH; cd07123
1030843005469	delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; Region: D1pyr5carbox1; TIGR01236
1030843005470	Glutamate binding site [chemical binding]; other site
1030843005471	NAD binding site [chemical binding]; other site
1030843005472	catalytic residues [active]
1030843005473	putative recombination protein RecB; Provisional; Region: PRK13909
1030843005474	Family description; Region: UvrD_C_2; pfam13538
1030843005475	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
1030843005476	putative acyl-acceptor binding pocket; other site
1030843005477	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1030843005478	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1030843005479	classical (c) SDRs; Region: SDR_c; cd05233
1030843005480	NAD(P) binding site [chemical binding]; other site
1030843005481	active site
1030843005482	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1030843005483	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1030843005484	active site
1030843005485	nucleotide binding site [chemical binding]; other site
1030843005486	HIGH motif; other site
1030843005487	KMSKS motif; other site
1030843005488	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1030843005489	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
1030843005490	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14466
1030843005491	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843005492	FeS/SAM binding site; other site
1030843005493	Protein of unknown function (DUF1661); Region: DUF1661; pfam07877
1030843005494	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1030843005495	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1030843005496	dimer interface [polypeptide binding]; other site
1030843005497	motif 1; other site
1030843005498	active site
1030843005499	motif 2; other site
1030843005500	motif 3; other site
1030843005501	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1030843005502	anticodon binding site; other site
1030843005503	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1030843005504	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1030843005505	folate binding site [chemical binding]; other site
1030843005506	NADP+ binding site [chemical binding]; other site
1030843005507	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1030843005508	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1030843005509	dimerization interface [polypeptide binding]; other site
1030843005510	active site
1030843005511	Peptidase family M48; Region: Peptidase_M48; pfam01435
1030843005512	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1030843005513	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1030843005514	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1030843005515	ABC transporter; Region: ABC_tran_2; pfam12848
1030843005516	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1030843005517	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005518	TPR motif; other site
1030843005519	binding surface
1030843005520	TPR repeat; Region: TPR_11; pfam13414
1030843005521	TPR repeat; Region: TPR_11; pfam13414
1030843005522	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005523	TPR motif; other site
1030843005524	binding surface
1030843005525	Tetratricopeptide repeat; Region: TPR_9; pfam13371
1030843005526	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005527	binding surface
1030843005528	TPR motif; other site
1030843005529	TPR repeat; Region: TPR_11; pfam13414
1030843005530	TPR repeat; Region: TPR_11; pfam13414
1030843005531	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005532	binding surface
1030843005533	TPR motif; other site
1030843005534	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1030843005535	TPR motif; other site
1030843005536	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1030843005537	binding surface
1030843005538	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1030843005539	active site
1030843005540	catalytic residues [active]
1030843005541	metal binding site [ion binding]; metal-binding site
1030843005542	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
1030843005543	MG2 domain; Region: A2M_N; pfam01835
1030843005544	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1030843005545	2-dehydropantoate 2-reductase; Region: apbA_panE; TIGR00745
1030843005546	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1030843005547	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1030843005548	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1030843005549	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1030843005550	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1030843005551	ABC transporter; Region: ABC_tran_2; pfam12848
1030843005552	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1030843005553	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1030843005554	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1030843005555	NAD(P) binding site [chemical binding]; other site
1030843005556	active site
1030843005557	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1030843005558	active site
1030843005559	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1030843005560	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1030843005561	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1030843005562	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1030843005563	Walker A/P-loop; other site
1030843005564	ATP binding site [chemical binding]; other site
1030843005565	Q-loop/lid; other site
1030843005566	ABC transporter signature motif; other site
1030843005567	Walker B; other site
1030843005568	D-loop; other site
1030843005569	H-loop/switch region; other site
1030843005570	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1030843005571	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
1030843005572	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
1030843005573	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1030843005574	Substrate binding site; other site
1030843005575	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1030843005576	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1030843005577	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1030843005578	TPP-binding site; other site
1030843005579	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1030843005580	PYR/PP interface [polypeptide binding]; other site
1030843005581	dimer interface [polypeptide binding]; other site
1030843005582	TPP binding site [chemical binding]; other site
1030843005583	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1030843005584	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1030843005585	TrkA-N domain; Region: TrkA_N; pfam02254
1030843005586	TrkA-C domain; Region: TrkA_C; pfam02080
1030843005587	TrkA-N domain; Region: TrkA_N; pfam02254
1030843005588	TrkA-C domain; Region: TrkA_C; pfam02080
1030843005589	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1030843005590	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1030843005591	Homologues of TraJ from Bacteroides conjugative transposon; Region: CtnDOT_TraJ; pfam07863
1030843005592	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1030843005593	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1030843005594	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1030843005595	FeS/SAM binding site; other site
1030843005596	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1030843005597	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1030843005598	putative acyl-acceptor binding pocket; other site
1030843005599	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1030843005600	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1030843005601	Probable Catalytic site; other site
1030843005602	metal-binding site
1030843005603	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1030843005604	Winged helix DNA-binding domain; Region: HTH_34; pfam13601
1030843005605	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1030843005606	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1030843005607	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629