-- dump date   	20140620_000931
-- class       	Genbank::Contig
-- table       	contig_comment
-- id	comment
NC_014039.1	PROVISIONAL REFSEQ: This record has not yet been subject to finalPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977.PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-sporePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. ThePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligatePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show betterPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionicPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to producePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate.PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology andPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of thePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. ThePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil,PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestivePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intensePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne isPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topicalPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, orPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals thatPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. ThisPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. SourcePROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School ofPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USAPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of AllergyPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap HumanPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01).PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolvedPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638.PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638. ##Genome-Assembly-Data-START##PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638. ##Genome-Assembly-Data-START## Finishing Goal           :: FinishedPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638. ##Genome-Assembly-Data-START## Finishing Goal           :: Finished Current Finishing Status :: FinishedPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638. ##Genome-Assembly-Data-START## Finishing Goal           :: Finished Current Finishing Status :: Finished Assembly Method          :: Newbler Assembler v. 1 1.03.24-64-7PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638. ##Genome-Assembly-Data-START## Finishing Goal           :: Finished Current Finishing Status :: Finished Assembly Method          :: Newbler Assembler v. 1 1.03.24-64-7 Genome Coverage          :: 22.4xPROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638. ##Genome-Assembly-Data-START## Finishing Goal           :: Finished Current Finishing Status :: Finished Assembly Method          :: Newbler Assembler v. 1 1.03.24-64-7 Genome Coverage          :: 22.4x Sequencing Technology    :: 454PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638. ##Genome-Assembly-Data-START## Finishing Goal           :: Finished Current Finishing Status :: Finished Assembly Method          :: Newbler Assembler v. 1 1.03.24-64-7 Genome Coverage          :: 22.4x Sequencing Technology    :: 454 ##Genome-Assembly-Data-END##PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to CP001977. Propionibacterium acnes is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum. This is a reference genome for the Human Microbiome Project. This project is co-owned with the Human Microbiome Project DACC. Source DNA provided by Martin Blaser, New York University School of Medicine, OBV 6 A606, 550 First Avenue, New York NY 10016, USA (Martin.Blaser@nyumc.org). Funded by National Institute of Allergy and Infectious Diseases on behalf of the NIH Roadmap Human Microbiome Project (U54-AI-084844-01). Finishing comments       The chromosome contains two unresolved homopolymer indels at the following locations: 2023501 and 2060638. ##Genome-Assembly-Data-START## Finishing Goal           :: Finished Current Finishing Status :: Finished Assembly Method          :: Newbler Assembler v. 1 1.03.24-64-7 Genome Coverage          :: 22.4x Sequencing Technology    :: 454 ##Genome-Assembly-Data-END## COMPLETENESS: full length.