-- dump date   	20140620_001210
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_003686962.1	DnaA, ATPase involved in DNA replication initiation
YP_003686965.1	1,4-alpha-D-glucan <=> 1,4-alpha-D-glucan
YP_003686966.1	UDP-glucose + HSO3- <=> UDP-6-sulfoquinovose + H2O
YP_003686970.1	RecF is a recombinational DNA repair ATPase that maintains replication in the presence of DNA damage
YP_003686977.1	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. ATP-dependent breakage, passage and rejoining of double-stranded DNA. Belongs to the type II topoisomerase family
YP_003686983.1	S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine <=> 5 prime-deoxyadenosine + L-methionine + Flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical
YP_003686989.1	myo-inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+
YP_003686994.1	carboxypeptidase activity
YP_003686997.1	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH
YP_003686999.1	Several members of this family contain peptidoglycan binding domains. So these proteins may use peptidoglycan or a precursor as a substrate.
YP_003687002.1	A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor.
YP_003687007.1	dTTP + D-glucose 1-phosphate <=> Pyrophosphate + dTDP-glucose
YP_003687008.1	transferase activity, transferring glycosyl groups
YP_003687010.1	transferase activity, transferring glycosyl groups
YP_003687012.1	transferring glycosyl groups
YP_003687013.1	possible EPS polymerase
YP_003687014.1	dTDP-4-dehydro-6-deoxy-alpha-D-glucose <=> dTDP-4-dehydro-6-deoxy-L-mannose / The enzyme occurs in a complex with EC 1.1.1.133 dTDP-4-dehydrorhamnose reductase/ dTDP-6-deoxy-L-mannose + NADP+ <=> dTDP-4-dehydro-6-deoxy-L-mannose + NADPH + H+
YP_003687015.1	dTDP-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O / dTDP-glucose <=> 4,6-Dideoxy-4-oxo-dTDP-D-glucose + H2O
YP_003687016.1	extracted as s-layer proteins
YP_003687017.1	Molecular function: UDP-galactopyranose mutase activity, Biological process: lipopolysaccharide biosynthetic process. UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.
YP_003687018.1	transfer of sugar
YP_003687022.1	transferase activity transferring glycosyl groups
YP_003687023.1	transferase activity transferring glycosyl groups
YP_003687025.1	signal peptid detected according to SignalP. 3 TM domains according to TMHMM
YP_003687029.1	ATP + Propanoate <=> ADP + Propanoyl phosphate / ATP + acetate <=> ADP + acetyl phosphate
YP_003687030.1	acetyl-CoA + Orthophosphate <=> CoA + acetyl phosphate / Propanoyl-CoA + Orthophosphate <=> Propanoyl phosphate + CoA
YP_003687038.1	phenol sulfate + H(2)O = a phenol + sulfate
YP_003687039.1	ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate
YP_003687040.1	sn-glycerol 3-phosphate + NAD+ <=> glycerone phosphate + NADH + H+ / sn-glycerol 3-phosphate + NADP+ <=> glycerone phosphate + NADPH + H+
YP_003687044.1	ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
YP_003687046.1	In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly.
YP_003687047.1	protein tyrosine phosphate + H2O <=> protein tyrosine + Orthophosphate
YP_003687049.1	carbamoyl phosphate + L-Ornithine <=> Orthophosphate + L-Citrulline
YP_003687050.1	Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. Required for DNA damage lesion repair in stationary-phase cells
YP_003687060.1	no peptide signal, 3 TM domains according to TMHMM
YP_003687061.1	Reduced acceptor + 2 Nitric oxide <=> Nitrous oxide + Acceptor + H2O / Nitric oxide + NADH + H+ <=> Nitrous oxide + NAD+ + H2O
YP_003687062.1	L-Leucyl-tRNA + protein <=> tRNA + L-Leucyl-protein
YP_003687073.1	ATP + D-gluconic acid <=> ADP + 6-phospho-D-gluconate
YP_003687075.1	L-Leucyl-tRNA + protein <=> tRNA + L-Leucyl-protein
YP_003687076.1	ATP + protein <=> ADP + phosphoprotein
YP_003687078.1	Citrate + CoA <=> acetyl-CoA + H2O + Oxaloacetate
YP_003687081.1	Subtilases are a family of serine proteases.
YP_003687082.1	L-alanine <=> D-alanine
YP_003687092.1	may play roles in distinct ADP-ribose pathways, such as the ADP-ribosylation of proteins, an important post-translational modification which occurs in DNA repair, transcription, chromatin biology, and long-term memory formation, among other processes.
YP_003687098.1	(R)-Pantoate + NADP+ <=> 2-Dehydropantoate + NADPH + H+
YP_003687102.1	L-Arogenate <=> L-Phenylalanine + H2O + CO2 and Prephenate <=> Phenylpyruvate + H2O + CO2
YP_003687104.1	ATP + L-serine + tRNA(Ser) <=> AMP + Pyrophosphate + L-Seryl-tRNA(Ser)
YP_003687110.1	ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
YP_003687112.1	peroxydase. Has antioxidant activity. Could remove peroxides or H(2)O(2)
YP_003687113.1	Modulates the activities of several enzymes which are inactive in their acetylated form. NAD+ + an acetylprotein = nicotinamide + O-acetyl-ADP-ribose + a protein
YP_003687115.1	ATP + L-Citrulline + L-aspartate <=> AMP + Pyrophosphate + N-(L-arginino)succinate
YP_003687121.1	confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te)Arthur M, Depardieu F, Molinas C, Reynolds P, Courvalin P; , Gene 1995;154:87-92.: The vanZ gene of Tn1546 from Enterococcus faecium BM4147 confers resistance to teicoplanin.
YP_003687122.1	Short-subunit alcohol dehydrogenase of unknown specificity
YP_003687123.1	glycerophosphodiester + H2O <=> Alcohol + sn-glycerol 3-phosphate
YP_003687124.1	Shikimate + NADP+ <=> 3-Dehydroshikimate + NADPH + H+ and Shikimate + NADP+ <=> 5-Dehydroshikimate + NADPH
YP_003687125.1	3-carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 3-carboxy-cis,cis-muconate Benzoate degradation via hydroxylation
YP_003687126.1	involved in ascorbate production 2-Dehydro-D-gluconate + NADP+ <=> 2,5-Didehydro-D-gluconate + NADPH + H+
YP_003687127.1	lipid transport ?
YP_003687136.1	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway.
YP_003687141.1	N-Succinyl-LL-2,6-diaminoheptanedioate + H2O <=> succinate + LL-2,6-diaminoheptanedioate
YP_003687142.1	Pfam domain
YP_003687150.1	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase , pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin
YP_003687151.1	(S)-dihydroorotate + Oxygen <=> Orotate + H2O2
YP_003687160.1	voir cd01189
YP_003687163.1	filamentation induced by cAMP protein . Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism. This family contains a central conserved motif HPFXXGNG in most members.
YP_003687171.1	This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.
YP_003687176.1	2-amino-4-hydroxy-6-hydroxymethyl-7, 8-dihydropteridine + 4-aminobenzoate <=> dihydropteroate + H2O / 2-amino-7, 8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine + 4-aminobenzoate <=> Pyrophosphate + dihydropteroate
YP_003687181.1	ATP + L-lysine + tRNA(Lys) <=> AMP + Pyrophosphate + L-Lysyl-tRNA
YP_003687183.1	Similar to Swiss-Prot entries Q9I1M2 and P09060
YP_003687184.1	44% identity with Swiss-Prot entry P09061
YP_003687185.1	Similarity to Swiss-Prot entry Q9IMO
YP_003687189.1	Chorismate + NH3 <=> Anthranilate + pyruvate + H2O Chorismate + L-glutamine <=> Anthranilate + pyruvate + L-glutamate
YP_003687199.1	Hg + NADP+ + H+ <=> Hg2+ + NADPH
YP_003687203.1	UDP-glucose = UDP-galactose
YP_003687205.1	Lactose + H2O <=> alpha-D-glucose + D-Galactose
YP_003687207.1	integrase core domain. integrase mediates integration of a DNA copy of the viral genome into the host chromosome.
YP_003687211.1	fatty acid metabolism and xenobiotic degradation
YP_003687212.1	Engemann et al. Cai locus and corresponding enzymes of Proteus sp.
YP_003687213.1	Could catalyze the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the caiB reaction cycle
YP_003687215.1	Belongs to the major facilitator superfamily. Sugar transporter
YP_003687217.1	Required for anaerobic carnitine reduction. May bring reductant to caiA
YP_003687218.1	Required for anaerobic carnitine reduction. May bring reductant to caiA
YP_003687223.1	UDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + H+
YP_003687224.1	ATP + L-arginine + tRNA(Arg) <=> AMP + Pyrophosphate + L-arginyl-tRNA(Arg)
YP_003687229.1	(phosphate)n + D-glucose = (phosphate)n-1 + D-glucose 6-phosphate
YP_003687231.1	# UDP-glucose <=> UDP-D-galactose dTDP-glucose <=> dTDP-galactose
YP_003687233.1	D-glucoside + H2O <=> ROH + alpha-D-glucose
YP_003687247.1	S-adenosyl-L-methionine + DNA <=> S-adenosyl-L-homocysteine + DNA 5-methylcytosine and S-adenosyl-L-methionine + DNA cytosine <=> S-adenosyl-L-homocysteine + DNA 5-methylcytosine
YP_003687252.1	2 acetyl-CoA <=> CoA + acetoacetyl-CoA and acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
YP_003687253.1	ATP + 2-Succinylbenzoate + CoA <=> AMP + Pyrophosphate + 2-Succinylbenzoyl-CoA
YP_003687257.1	Expression of DPS is induced by oxidative or nutritional stress, including metal ion starvation.
YP_003687275.1	over representated in Mycobacterium smegmatis
YP_003687284.1	Pyrophosphate + H2O <=> 2 Orthophosphate
YP_003687285.1	3-phosphoglycerate + NAD+ <=> 3-phosphonooxypyruvate + NADH + H+ glycine, serine, threonine metabolism
YP_003687286.1	2-Dehydro-3-deoxy-D-gluconate + NAD+ <=> (4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADH + H+ and 2-deoxy-D-gluconate + NAD+ <=> 3-Dehydro-2-deoxy-D-gluconate + NADH + H+
YP_003687287.1	acyl-CoA + acetate = a fatty acid anion + acetyl-CoA OR: succinate + acetyl-CoA = succinyl-CoA + acetate OR (in Pf): succinate + propionyl-CoA = succinyl-CoA + propionate
YP_003687290.1	Young IG, Gibson F. Biochim. Biophys. Acta. 177 (1969) 401-11. Isochorismate + H2O <=> 2,3-dihydro-2,3-dihydroxybenzoate + pyruvate
YP_003687294.1	S-adenosyl-L-methionine + rRNA <=> S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine
YP_003687295.1	These proteins mediate resistance to a wide range of cationic dyes, fluroquinolones, aminoglycosides and other structurally diverse antibodies and drugs.
YP_003687296.1	Involved in the acceptance of foreign DNA which is modified. Restricts both adenine- and cytosine-methylated DNA.
YP_003687299.1	ATP + pyruvate + Orthophosphate <=> AMP + phosphoenolpyruvate + Pyrophosphate Cofactor : Magnesium. homodimer
YP_003687302.1	two component system regulator
YP_003687303.1	highly similar to protein Q9ADN7_STRCO from Streptomyces coelicolor
YP_003687309.1	This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.
YP_003687312.1	ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine <=> ADP + 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate
YP_003687313.1	2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphoethyl)-thiazole <=> Pyrophosphate + Thiamin monophosphate
YP_003687314.1	ATP + 5-(2-Hydroxyethyl)-4-methylthiazole <=> ADP + 4-methyl-5-(2-phosphoethyl)-thiazole
YP_003687321.1	Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection.
YP_003687341.1	carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate. Initiates both the urea cycle and the biosynthesis of arginine and/or pyrimidines. heterodimer of a small and large subunit. The small subunit promotes the hydrolysis of glutamine to ammonia, which is used by the large subunit to synthesise carbamoyl phosphate.
YP_003687354.1	hemerythrin is an oligomeric protein responsible for oxygen (O2) transportation. hemerythrin was discovered in methanotrophic bacterium methylococcus capsulatus.
YP_003687357.1	transmembrane and signal peptide (TM HMM and Signal P)
YP_003687358.1	signal peptide (SignalP), transmembranaire C term (TM HMM) (carboxypeptidase ?)
YP_003687359.1	Sortase, Sortase domain; transpeptidase of Gram-positive bacteria, cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond
YP_003687362.1	May play a role in DNA repair. It seems to be involved in an recBC-independent recombinational process of DNA repair. It may act with recF and recO
YP_003687364.1	ATP + L-Isoleucine + tRNA(Ile) <=> AMP + Pyrophosphate + L-Isoleucyl-tRNA(Ile)
YP_003687366.1	ATP + L-aspartate <=> ADP + 4-phospho-L-aspartate
YP_003687368.1	ATP + L-lysine + tRNA(Lys) <=> AMP + Pyrophosphate + L-Lysyl-tRNA
YP_003687370.1	ATP + D-Fructose <=> ADP + D-Fructose 6-phosphate
YP_003687378.1	ATP + 5-phosphoribosylamine + glycine <=> ADP + Orthophosphate + 5prime-phosphoribosylglycinamide
YP_003687379.1	N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP 1-(5prime-phosphoribosyl)-5-amino-4-(N- succinocarboxamide)-imidazole These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits
YP_003687381.1	catalyzes the seventh step of the de novo biosynthesis of purine nucleotides, the conversion of carboximideaminoimidazole ribonucleotide (CAIR) into succinoaminoimidazolecarboximide ribonucleotide (SAICAR). CAIR and aspartic acid react in the presence of ATP and magnesium to form SAICAR.
YP_003687382.1	ATP + 1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-aspartate <=> ADP + Orthophosphate + 1-(5-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)- imidazole
YP_003687383.1	ATP + 5prime-phosphoribosyl-N-formylglycinamide + L-glutamine + H2O <=> ADP + Orthophosphate + 2-(formamido)-N1-(5prime-phosphoribosyl)acetamidine + L-glutamate
YP_003687387.1	No signal peptide (signalP) and 2 TM domains
YP_003687408.1	reversible isomerization of glucose-6-phosphate : D-glucose 6-phosphate = D-fructose 6-phosphate
YP_003687413.1	recombinant protein active on 1- naphthyl propionate, extracellular (see dherbecourt 2010, AEM)
YP_003687415.1	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3prime->5prime double strand exonuclease that can open hairpins. It also has a 5prim single-strand endonuclease activity
YP_003687417.1	adenosine + H2O <=> inosine + NH3 and deoxyadenosine + H2O <=> deoxyinosine + NH3 and Cyclic amidines + H2O <=> Cyclic amide + NH3
YP_003687430.1	Reduced riboflavin + NADP+ <=> riboflavin + NADPH + H+
YP_003687434.1	* 2 S-adenosyl-L-methionine + Uroporphyrinogen III <=> 2 S-adenosyl-L-homocysteine + Precorrin 2
YP_003687435.1	Part of the ABC transporter complex cbiONQ involved in cobalt import. Responsible for energy coupling to the transport system - The complex is composed of two ATP-binding proteins (cbiO), fused or not, two transmembrane proteins (cbiQ) and a solute-binding protein (cbiN)
YP_003687437.1	CbiN is part of the active cobalt transport system involved in uptake of cobalt in to the cell involved with cobalamin biosynthesis (vitamin B12)
YP_003687440.1	SignalP : Signal peptide probability: 0.976 Max cleavage site probability: 0.772 between pos. 39 and 40
YP_003687441.1	6-phospho-D-gluconate + NADP+ <=> D-Ribulose 5-phosphate + CO2 + NADPH + H+
YP_003687442.1	Belongs to the heat shock protein 70 family. Acts as a chaperone. Several 70 to 75 kda Hsp70 chaperones are expressed as disctinct heat shock proteins
YP_003687443.1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with dnaK
YP_003687444.1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins
YP_003687445.1	Binds to three inverted repeats (IR1-IR3) in the promoter region of the dnaK operon
YP_003687446.1	ATP + N-acetyl-D-glucosamine <=> ADP + N-acetyl-D-glucosamine 6-phosphate
YP_003687447.1	ATP + 5 prime-phosphoribosyl-N-formylglycinamide + L-glutamine + H2O <=> ADP + Orthophosphate + 2-(formamido)-N1-(5 prime-phosphoribosyl)acetamidine + L-glutamate
YP_003687451.1	ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate
YP_003687456.1	5-phosphoribosylamine + Pyrophosphate + L-glutamate <=> L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O
YP_003687460.1	recombinant protein active on 1- naphthyl actetate and 1- naphthyl propionate
YP_003687467.1	SignalP : Signal anchor transmembrane according to TM HMM
YP_003687468.1	L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
YP_003687469.1	(R)-Pantoate + NADP+ <=> 2-Dehydropantoate + NADPH + H+
YP_003687472.1	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
YP_003687477.1	Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.
YP_003687478.1	dCMP + H2O <=> dUMP + NH3 deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP
YP_003687483.1	Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side subunit to DHNA. The conversion of DHNA to DMK proceeds in three stages: the removal of the carboxyl group of DHNA as CO(2), the attachment of the isoprenoid side subunit, and a quinol-to-quinone oxidation, which is thought to be spontaneous
YP_003687485.1	methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) / S-adenosyl-L-methionine + demethylmenaquinol = s-adenosyl-L-homocysteine + menaquinol / Cofactor biosynthesis; menaquinone biosynthesis; menaquinone from chorismate: step 7/7.
YP_003687488.1	Chorismate <=> Isochorismate
YP_003687491.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687492.1	# Ubiquinol + NAD+ <=> Ubiquinone + NADH + H+
YP_003687493.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687494.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687495.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687496.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687497.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687498.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687499.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687500.1	Ubiquinol + NAD+ <=> Ubiquinone + NADH + H+ / Ubiquinol <=> Ubiquinone + 2 H+
YP_003687501.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687502.1	Acceptor + NADH + H+ <=> Reduced acceptor + NAD+
YP_003687503.1	Ubiquinol + NAD+ <=> Ubiquinone + NADH + H+
YP_003687504.1	Ubiquinol + NAD+ <=> Ubiquinone + NADH + H+ / Ubiquinol <=> Ubiquinone + 2 H+
YP_003687505.1	all-trans-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + Pyrophosphate
YP_003687508.1	In bacteria they may be used for digestion of milk. believed to be involved with milk protein cleavage.
YP_003687513.1	Exonucleolytic cleavage in the 3 prime- to 5 prime -direction to yield nucleoside 5 prime-phosphates
YP_003687515.1	2 RSH + ROOH <=> R-S-S-R + H2O + ROH
YP_003687519.1	Catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. The structure of the monomer includes a five-strand antiparallel beta-sheet wrapped around a central alpha helix, referred to as a hot dog fold. The active site lies within a substrate-binding tunnel formed by the homodimer
YP_003687526.1	Catalyzes the transfer of the endogenously synthesized lipoate to apoproteins, creating an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoate-dependent enzymes. Utilizes lipoyl-acyl-carrier-protein as a source of lipoyl groups.
YP_003687527.1	Octanoyl-ACP + 2 sulfurs = lipoyl-ACP. Catalyzes the radical-mediated insertion of two sulfur atoms into an octanoyl group bound to acyl-carrier-protein (ACP) to produce a lipoyl group
YP_003687534.1	RNA polymerases catalyse the DNA dependent polymerisation of RNA. Prokaryotes contain a single RNA polymerase
YP_003687542.1	integrase core domain. integrase mediates integration of a DNA copy of the viral genome into the host chromosome.
YP_003687552.1	highly similar to SwissProt entry RL16_PROAC from Propionibacterium acnes
YP_003687554.1	highly similar to Swissprot entry RS17_PROAC from Propionibacterium acnes
YP_003687560.1	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center, Part of the 50S ribosomal subunit, elongs to the ribosomal protein L6P family
YP_003687566.1	5,10-methylenetetrahydromethanopterin + Coenzyme F420 <=> 5,10-methenyltetrahydromethanopterin + Reduced coenzyme F420
YP_003687571.1	Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel. One of seven secretory proteins (secA-F and secY) that comprise the prokaryotic protein translocation apparatus. cell membrane; Multi-pass membrane protein.
YP_003687572.1	ATP + AMP = 2 ADP.
YP_003687573.1	Removes the amino-terminal methionine from nascent proteins. Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. Binds 2 cobalt ions per subunit. Belongs to the peptidase M24A family
YP_003687578.1	highly similar to SwissProt entry RS13_BIFLO from Bifidobacterium longum
YP_003687583.1	transferase activity transferring glycosyl groups
YP_003687594.1	tRNA uridine <=> tRNA pseudouridine
YP_003687595.1	S-adenosyl-L-methionine + tRNA <=> S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine
YP_003687597.1	GTP + H2O <=> GDP + Orthophosphate
YP_003687600.1	alpha-D-glucosamine 1-phosphate <=> D-glucosamine 6-phosphate
YP_003687601.1	ATP + (R)-pantothenate = ADP + (R)-4-phosphopantothenate
YP_003687602.1	* L-glutamine + D-Fructose 6-phosphate <=> L-glutamate + D-glucosamine 6-phosphate . Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_003687603.1	CoA + Apo-ACP <=> adenosine 3prime,5prime-bisphosphate + acyl-carrier protein
YP_003687605.1	glycosyl transferases group 1
YP_003687609.1	acetyl-CoA + ribosomal-protein L-alanine <=> CoA + ribosomal-protein N-acetyl-L-alanine
YP_003687610.1	Could be a metalloprotease.Hydrolysis of O-sialoglycoproteins; cleaves 31-Arg-|-Asp-32 bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated. Belongs to the peptidase M22 family.
YP_003687612.1	nactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. Belongs to the peptidase C1 family.
YP_003687621.1	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. groL1 and groL2 are expressed as 2 distinct heat shock proteins
YP_003687623.1	IMP + NAD+ + H2O <=> Xanthosine 5 prime-phosphate + NADH + H+
YP_003687625.1	Chorismate mutase EC:5.4.99.5 catalyses the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine
YP_003687630.1	L-serine + acetyl-CoA <=> O-acetyl-L-serine + CoA
YP_003687632.1	L-ribulose 5-phosphate = D-xylulose 5-phosphate. L-arabinose catabolism; third step. Belongs to the aldolase class II family. AraD/fucA subfamily. The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression. Microbiology 143,957-969(1997).
YP_003687634.1	L-arabinose = L-ribulose. L-arabinose catabolism; first step. Belongs to the arabinose isomerase family. This reaction is the first step in the pathway of L-arabinose utilisation as a carbon source after entering the cell L-arabinose is converted into L-ribulose by the L-arabinose isomerases enzyme.
YP_003687636.1	locus abc transport
YP_003687637.1	Molecular function: ATP binding. Responsible for energy coupling to the transport system
YP_003687639.1	locus abc transport.
YP_003687650.1	highly similar to Q411B6_KINRA from Kineococcus radiotolerans SRS30216 and COG domain
YP_003687654.1	10-formyltetrahydrofolate + 5prim-phosphoribosylglycinamide <=> Tetrahydrofolate + 5prim-phosphoribosyl-N-formylglycinamide and 5prim-phosphoribosylglycinamide + 5,10-methenyltetrahydrofolate + H2O <=> 5prim-phosphoribosyl-N-formylglycinamide + Tetrahydrofolate
YP_003687655.1	10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4- carboxamide and IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4- carboxamide
YP_003687656.1	5,10-methylenetetrahydrofolate + NADP+ <=> 5,10-methenyltetrahydrofolate + NADPH + H+ / Tetrahydrofolate + formate + ATP <=> ADP + Orthophosphate + 10-formyltetrahydrofolate
YP_003687658.1	(S)-malate + NAD+ = oxaloacetate + NADH.
YP_003687659.1	Isocitrate + NADP+ <=> Oxalosuccinate + NADPH + H+
YP_003687663.1	no signal peptid, no TM domain
YP_003687665.1	Endonuclease that specifically degrades the RNA of RNA-DNA hybrids
YP_003687669.1	atalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, producing nicotinamide and the novel metabolite O-acetyl-ADP-ribose. shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span.
YP_003687673.1	2-carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate + CO2
YP_003687680.1	(S)-dihydroorotate + Oxygen <=> Orotate + H2O2
YP_003687682.1	ATP + acetyl-CoA + HCO(3)(-) <=> ADP + phosphate + malonyl-CoA
YP_003687683.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3- and 5-phosphates
YP_003687687.1	implicated in inhibition of septum
YP_003687689.1	ATP + propanoyl-CoA + HCO(3)(-) <=> ADP + phosphate + (S)-methylmalonyl-CoA
YP_003687696.1	biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. ATP + biotin + Apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Pyrophosphate + [acetyl-CoA:carbon-dioxide ligase (ADP-forming)]
YP_003687700.1	peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. type 1 glutamine amidotransferase
YP_003687702.1	1-(5-phospho-D-ribosyl)-5-amino-4- imidazolecarboxylate <=> aminoimidazole ribotide + CO2
YP_003687706.1	highly similar to A0LS21 from Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
YP_003687711.1	alpha-D-mannose 1-phosphate = D-mannose 6-phosphate
YP_003687717.1	pfam06271, RDD family. This family of proteins contain 3 highly conserved amino acids: one arginine and two aspartates. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown but may be involved in transport of an as yet unknown set of ligands
YP_003687718.1	transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.
YP_003687719.1	1R,6R)-6-hydroxy-2-succinylcyclohexa-2, 4-diene-1-carboxylate = 2-succinylbenzoate + H2O.
YP_003687720.1	2-Oxoglutarate + Isochorismate <=> 2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate + CO2 . Bifunctional 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
YP_003687721.1	UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A). The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_003687723.1	Chorismate <=> Isochorismate
YP_003687724.1	ATP + 2-Succinylbenzoate + CoA <=> AMP + Pyrophosphate + 2-Succinylbenzoyl-CoA - Cofactor biosynthesis; menaquinone biosynthesis; menaquinone from chorismate: step 4/7.
YP_003687725.1	2-Succinylbenzoyl-CoA <=> 1,4-dihydroxy-2-naphthoate + CoA . Cofactor biosynthesis; menaquinone biosynthesis; menaquinone from chorismate: step 5/7
YP_003687726.1	Nicotinate D-ribonucleotide + Pyrophosphate <=> Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate
YP_003687729.1	L-glutamate <=> D-glutamate
YP_003687730.1	3 prime exoribonuclease family, domain 1. This family includes 3 prime-5 prime exoribonucleases. ribonuclease PH contains a single copy of this domain, and removes nucleotide residues following the -CCA terminus of tRNA.
YP_003687732.1	Provides the sole de novo source of dTMP for DNA biosynthesis - dUMP + 5,10-methylenetetrahydrofolate <=> dihydrofolate + dTMP
YP_003687733.1	5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH. tetrahydrofolate biosynthesis; tetrahydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 3/3.
YP_003687734.1	deoxynucleoside triphosphate + DNA <=> Pyrophosphate + DNA
YP_003687736.1	methylmalonyl-CoA mutase catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Induced by heat and acid stresses.
YP_003687737.1	methylmalonyl-CoA mutase catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Induced by heat and acid stresses.
YP_003687739.1	cobalt-precorrin 2 + S-adenosyl-L-methionine <=> cobalt-precorrin 3 + S-adenosyl-L-homocysteine
YP_003687740.1	# S-adenosyl-L-methionine + Precorrin 4 <=> S-adenosyl-L-homocysteine + Precorrin 5
YP_003687741.1	S-adenosyl-L-methionine + Precorrin 3B <=> S-adenosyl-L-homocysteine + Precorrin 4 / cobalt-precorrin 3 + S-adenosyl-L-methionine <=> cobalt-precorrin 4 + S-adenosyl-L-homocysteine
YP_003687742.1	cobalt fixation on precorrin 2
YP_003687744.1	* Precorrin 8X <=> Hydrogenobyrinate
YP_003687747.1	# Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+
YP_003687748.1	L-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate
YP_003687752.1	adenosyl cobyrinate a,c diamide + 4 L-glutamine + 4 ATP + 4 H2O <=> adenosyl cobyrinate hexaamide + 4 L-glutamate + 4 Orthophosphate + 4 ADP
YP_003687753.1	ATP + Long-subunit carboxylate + CoA <=> AMP + Pyrophosphate + acyl-CoA
YP_003687754.1	protein tyrosine phosphate + H2O <=> protein tyrosine + Orthophosphate
YP_003687765.1	ATP + glycerone <=> ADP + glycerone phosphate
YP_003687766.1	Complexation with ADP increases the thermal unfolding temperature from 40 to 65 degrees Celsius ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL-ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sensor domain of dhaR. DhaL-ATP is inactive.
YP_003687768.1	UDP-glucose + alpha-D-Galactose 1-phosphate <=> D-glucose 1-phosphate + UDP-D-galactose
YP_003687770.1	Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides. Hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1 is Pro, or both P1 and P1 are Gly.
YP_003687772.1	pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.
YP_003687773.1	ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Pyrophosphate / ATP + Long-subunit carboxylate + CoA <=> AMP + Pyrophosphate + acyl-CoA
YP_003687775.1	ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine <=> ADP + 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate
YP_003687776.1	6-phospho-D-gluconate + NADP+ <=> D-Ribulose 5-phosphate + CO2 + NADPH + H+
YP_003687777.1	aminopeptidase with broad substrate specificity. Preference for leucine, cleaves also next to Arg and lysine. Release of an N-terminal aa, Xaa-|-Yaa-. Xaa is preferably Ala. Xaa-Pro may be released. peptidase M1 family. Monomer. Binds 1 zinc ion per subunit, Cytoplasmic.
YP_003687780.1	NAD+ + DNA <=> AMP + Nicotinamide D-ribonucleotide + DNA
YP_003687785.1	Belongs to the small multidrug resistance (SMR) protein family
YP_003687786.1	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
YP_003687791.1	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of clpP
YP_003687793.1	O-phospho-L-homoserine + H2O <=> L-Threonine + Orthophosphate / O-phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate
YP_003687794.1	ATP + D-Fructose 6-phosphate <=> ADP + D-Fructose 1,6-bisphosphate
YP_003687798.1	protein-disulfide isomerase
YP_003687800.1	ATP + Tetrahydrofolate + L-glutamate <=> ADP + Orthophosphate + Tetrahydrofolyl-[Glu](2)
YP_003687805.1	No signal peptide (signalP), membrane protein (TM HMM)
YP_003687814.1	ATP + L-glutamate <=> ADP + L-glutamyl 5-phosphate
YP_003687816.1	Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
YP_003687818.1	# ATP + Nicotinamide D-ribonucleotide <=> Pyrophosphate + NAD+
YP_003687820.1	2-phospho-D-glycerate <=> 3-phospho-D-glycerate and 3-phospho-D-glyceroyl phosphate <=> 2,3-Bisphospho-D-glycerate
YP_003687826.1	(S)-dihydroorotate + H2O <=> N-carbamoyl-L-aspartate
YP_003687827.1	The protein has been identified by proteomics as a 70 kDa / PI 5.9 protein induced by various stresses including starvation
YP_003687832.1	Binds directly to 16S ribosomal RNA
YP_003687836.1	Coproporphyrinogen III + Oxygen <=> Protoporphyrinogen IX + 2 CO2 + 2 H2O
YP_003687840.1	3 pralogs of dnaj exist in P.freudenreichii, comprised in the 3 operons dnaK1, dnaK2 and hrcA.
YP_003687845.1	Specifically catalyzes the removal of N-terminal proline residues from peptides, Release of N-terminal proline from a peptide, Belongs to the peptidase S33 family, cytoplasmic
YP_003687851.1	Binds both GDP and GTP, has an intrinsic GTPase activity and is essential for cell growth
YP_003687856.1	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). acetyl-CoA + 3-methyl-2-oxobutanoate + H2O = (2S)-2-isopropylmalate + CoA. (2S)-2-Isopropylmalate + CoA <=> acetyl-CoA + 3-methyl-2-oxobutanoic acid + H2O
YP_003687858.1	Generates UDP pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. trans,trans,cis-Geranylgeranyl diphosphate + 7 Isopentenyl diphosphate <=> di-trans,poly-cis-UDP diphosphate + 7 Pyrophosphate
YP_003687859.1	Involved in DNA repair and recF pathway recombination
YP_003687860.1	Positive regulatory protein of pdu and cob operons.
YP_003687862.1	glycerol metabolism
YP_003687863.1	cobalamin-dependent degradation of ethanolamine
YP_003687864.1	glycerol metabolism
YP_003687865.1	glycerol degradation
YP_003687868.1	glycerol degradation
YP_003687869.1	glycerol degradation
YP_003687870.1	glycerol metabolism
YP_003687875.1	glycerol metabolism
YP_003687876.1	glycerol metabolism
YP_003687877.1	glycerol metabolism
YP_003687879.1	pfam01475, Ferric uptake regulator family. This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes.
YP_003687884.1	Nicotinate D-ribonucleotide + Pyrophosphate + CO2 <=> Pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
YP_003687885.1	Catalyzes the oxidation of L-aspartate to iminoaspartate. L-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.
YP_003687886.1	Cofactor biosynthesis; NAD(+) biosynthesis; pyridine-2,3-dicarboxylate from iminoaspartate: step 1/1.
YP_003687888.1	succinate + FAD <=> FADH2 + Fumarate and succinate + Acceptor <=> Fumarate + Reduced acceptor
YP_003687889.1	# succinate + FAD <=> FADH2 + Fumarate , A flavoprotein (FAD) containing iron-sulfur centres. A component of EC 1.3.5.1 succinate dehydrogenase (ubiquinone)
YP_003687890.1	# succinate + FAD <=> FADH2 + Fumarate
YP_003687891.1	Members of this family catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
YP_003687892.1	dGTP + H2O <=> deoxyguanosine + Triphosphate
YP_003687893.1	Signal peptide
YP_003687895.1	In the pyruvate dehydrogenase complex, it binds to the core of EC 2.3.1.12, and catalyses oxidation of its dihydrolipoyl groups. It plays a similar role in the oxoglutarate and 3-methyl-2-oxobutanoate dehydrogenase complexes pyruvate + CoA + NAD+ <=> acetyl-CoA + CO2 + NADH
YP_003687896.1	Predicted hydrolases of the HAD superfamily
YP_003687905.1	acetyl-CoA + acyl-carrier protein <=> CoA + acetyl-ACP
YP_003687906.1	4 prime-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
YP_003687907.1	acetyl-CoA + malonyl-ACP = acetoacyl-ACP + CoA + CO2
YP_003687908.1	recombinant protein active on 1- naphthyl actetate and 1- naphthyl propionate
YP_003687910.1	L-aspartate + 2-Oxoglutarate <=> Oxaloacetate + L-glutamate
YP_003687911.1	pyruvate + Enzyme N6-(lipoyl)lysine <=> [dihydrolipoyllysine-residue acetyltransferase]S-acetyldihydrolipoyllysine + CO2 , The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)
YP_003687914.1	Belongs to the small heat shock protein (HSP20) family.These seem to act as chaperones that can protect other proteins against heat-induced denaturation and aggregation. Hsp20 proteins seem to form large heterooligomeric aggregates. Structurally, this family is characterized by the presence of a conserved C-terminal domain of about 100 residues.
YP_003687918.1	4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde +
YP_003687919.1	FN3K catalyzes phosphorylation of fructosamines formed by glycation, the nonenzymatic reaction of glucose with primary amines followed by Amadori rearrangement. phosphorylation of fructosamines may initiate metabolism of the modified amine and result in deglycation of glycated proteins (Delpierre et al., 2000).
YP_003687920.1	It does however suggest that Yqey and its relatives have a role in tRNA metabolism.
YP_003687921.1	voir aussi #2872 (RF-1)
YP_003687930.1	Members of phosphoribosyltransferase (PRT) are catalytic and are regulatory proteins involved in nucleotide synthesis and salvage. Not all PRT proteins are enzymes. For example, in some bacteria PRT proteins regulate the expression of purine and pyrimidine synthetic genes.
YP_003687932.1	SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. SecA possesses the ATPase activity.
YP_003687938.1	ATP + L-tryptophan + tRNA(Trp) <=> AMP + Pyrophosphate + L-tryptophanyl-tRNA(Trp)
YP_003687944.1	REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA.
YP_003687949.1	Exonuc_V_gamma, exodeoxyribonuclease V, gamma subunit. The exodeoxyribonuclease V enzyme is a multi-subunit enzyme comprised of the proteins RecB, RecC (this family) and RecD. This enzyme plays an important role in homologous genetic recombination, repair of double strand DNA breaks resistance to UV irradiation and chemical DNA-damage.
YP_003687962.1	peptide + H2O <=> L-proline + peptide
YP_003687964.1	Dethiobiotin + Sulfur + 2 S-adenosyl-L-methionine <=> biotin + 2 L-methionine + 2 5prim-deoxyadenosine
YP_003687970.1	erythronate-4-phosphate + NAD+ = 2-oxo-3-hydroxy-4-phosphobutanoate + NADH and 3-phosphoglycerate + NAD+ = 3-phospho-hydroxypyruvate + NADH
YP_003687972.1	Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
YP_003687977.1	The engC protein is an unusual, circularly permuted GTPase that catalyzes rapid hydrolysis of GTP with comparatively slow catalytic turnover.
YP_003687978.1	phosphoenolpyruvate + Shikimate 3-phosphate <=> Orthophosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate
YP_003687985.1	Annotated from high similarity with Swiss-Prot entry Q8NRC3, a bifunctional enzyme of Corynebacterium glutamicum with E1 and E2 activity. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
YP_003687990.1	lysine metabolism meso-2,6-diaminoheptanedioate <=> L-lysine + CO2
YP_003687991.1	L-Homoserine + NAD+ <=> L-aspartate 4-semialdehyde + NADH + H+ and L-Homoserine + NADP+ <=> L-aspartate 4-semialdehyde + NADPH + H+
YP_003687992.1	O-phospho-L-serine + H2O <=> L-serine + Orthophosphate and D-O-phosphoserine + H2O <=> D-serine + Orthophosphate
YP_003687995.1	voir aussi #2872
YP_003687997.1	Sua5_yciO_yrdC, yrdC domain. This domain has been shown to preferentially bind to dsRNA. The domain is found in SUA5 as well as HypF and YrdC
YP_003687998.1	Catalyzes the formation of UDP-PP-N-acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B.subtilis. UDP-N-acetyl-D-glucosamine + UDP phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-undecaprenol
YP_003688002.1	Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane [H]. ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out)
YP_003688003.1	This is one of the three subunits of the nonenzymatic component (CF(0) subunit) of the ATPase complex [H]
YP_003688005.1	This protein seems to be part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) into CF(1) or is implicated in proton conduction [H]. ATP + H2O + H+(In) = ADP + phosphate + H+(Out)
YP_003688006.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha subunit is a regulatory subunit
YP_003688007.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma subunit is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
YP_003688008.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YP_003688009.1	Produces ATP from ADP in the presence of a proton gradient across the membrane.
YP_003688012.1	This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation.The EutT enzyme appears to be an adenosyl transferase converting CNB12 to AdoB12.
YP_003688018.1	(R)-2-methyl-3-oxopropanoyl-CoA <=> (S)-2-methyl-3-oxopropanoyl-CoA
YP_003688020.1	D-glucose 1-phosphate <=> alpha-D-glucose 6-phosphate
YP_003688022.1	1,4-alpha-D-glucan <=> glycogen
YP_003688024.1	Catalyzes the conversion of maltose into alpha,alpha-trehalose by transglucosylation. Annotated from blastp from sequence of (Cardoso et al, 2007 PubMed 17185556)
YP_003688026.1	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.
YP_003688030.1	S-adenosyl-L-methionine + tRNA <=> S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate
YP_003688031.1	5-methyltetrahydropteroyltri-L-glutamate + L-Homocysteine <=> Tetrahydropteroyltri-L-glutamate + L-methionine
YP_003688033.1	his family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Pairs of ACT domains bind specifically to a particular amino acid leading to regulation of the linked enzyme.
YP_003688034.1	ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate.
YP_003688035.1	Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
YP_003688036.1	ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate.
YP_003688038.1	Belongs to the peptidase M24B family, cell membrane; multi-pass membrane protein potential, potentially binds 2 manganese ions per subunit
YP_003688040.1	contains C-terminal CBS domain
YP_003688041.1	highly similar to Swiss-Prot entry P0A192
YP_003688042.1	highly similar with Swiss-Prot entries P0A194 and P0A958, COG
YP_003688043.1	31% identity with Swiss-Prot entry P30296 and P22729. Part of the binding-protein-dependent transport system for branched-subunit amino acids. Probably responsible for the translocation of the substrates across the membrane.
YP_003688044.1	Annotated from similarity Swiss-Prot entry P21627. Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I).
YP_003688046.1	In the pyruvate dehydrogenase complex, it binds to the core of EC 2.3.1.12, and catalyses oxidation of its dihydrolipoyl groups. It plays a similar role in the oxoglutarate and 3-methyl-2-oxobutanoate dehydrogenase complexes. Another substrate is the dihydrolipoyl group in the H-protein of the glycine-cleavage system, in which it acts with EC 1.4.4.2 and EC 2.1.2.10 to break down glycine.
YP_003688047.1	cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine.
YP_003688048.1	# ATP + Pyridoxal <=> ADP + Pyridoxal phosphate
YP_003688050.1	glycerophosphodiester + H2O <=> Alcohol + sn-glycerol 3-phosphate
YP_003688052.1	GDP-mannose + Dolichyl phosphate <=> GDP + Dolichyl phosphate D-mannose
YP_003688057.1	acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine
YP_003688063.1	Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment
YP_003688079.1	Cytidylate kinase EC:2.7.4.14 catalyses the phosphorylation of cytidine 5prime-monophosphate (dCMP) to cytidine 5prime-diphosphate (dCDP) in the presence of ATP or GTP
YP_003688080.1	Prephenate + NAD+ <=> 3-(4-Hydroxyphenyl)pyruvate + CO2 + NADH + H+
YP_003688081.1	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. Cleavage of peptide bonds with very broad specificity.
YP_003688082.1	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH
YP_003688083.1	S-adenosyl-L-methionine + tRNA <=> S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine
YP_003688086.1	5-methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-methionine
YP_003688088.1	Paralogue with PF#2086 . Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.
YP_003688089.1	D-ribulose 5-phosphate = D-xylulose 5-phosphate
YP_003688091.1	L-methionyl-tRNA + 10-formyltetrahydrofolate <=> Tetrahydrofolate + N-formylmethionyl-tRNA
YP_003688092.1	Recognizes a specific hairpin sequence on phiX ssDNA. This structure is then recognized and bound by proteins priB and priC. formation of the primosome proceeds with the subsequent actions of dnaB, dnaC, dnaT and primase. PriA then functions as a helicase within the primosome
YP_003688093.1	# Orthophosphate + Pyrophosphate + S-adenosyl-L-methionine <=> ATP + L-methionine + H2O / ATP + Selenomethionine + H2O <=> Orthophosphate + Pyrophosphate + Se-adenosylselenomethionine
YP_003688095.1	ATP + GMP <=> ADP + GDP
YP_003688097.1	Orotidine 5 prime-phosphate <=> UMP + CO2
YP_003688099.1	2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate ; Binds 3 manganese ions per subunit
YP_003688100.1	The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides
YP_003688102.1	NusB family. The NusB protein is involved in the regulation of rRNA biosynthesis by transcriptional antitermination.
YP_003688104.1	2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate <=> 3-Dehydroquinate + Orthophosphate
YP_003688105.1	5-O-(1-carboxyvinyl)-3-phosphoshikimate <=> Chorismate + Orthophosphate
YP_003688106.1	4-amino-4-deoxychorismate <=> 4-aminobenzoate + pyruvate
YP_003688107.1	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination.
YP_003688108.1	ATP + L-alanine + tRNA(Ala) <=> AMP + Pyrophosphate + L-Alanyl-tRNA
YP_003688109.1	(S)-Lactate + NAD+ <=> pyruvate + NADH + H+
YP_003688113.1	2-acetolactate <=> (R)-acetoin + CO2 - (S)-2-acetolactate <=> (R)-acetoin + CO2
YP_003688117.1	ATP + GTP <=> AMP + Guanosine 3 prime -diphosphate 5 prime -triphosphate
YP_003688118.1	AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
YP_003688119.1	multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC.
YP_003688121.1	transmembrane domain in N-term
YP_003688122.1	The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday junction migration by localized denaturation and reannealing
YP_003688123.1	The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of ruvB
YP_003688124.1	# nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5terminal phosphate and a 3terminal hydroxyl group
YP_003688127.1	1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide.
YP_003688128.1	5-[(5-phospho-1-deoxyribulos-1- ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4- carboxamide + L-glutamine = imidazole-glycerol phosphate + 5-aminoimidazol-4-carboxamide ribonucleotide + L-glutamate + H2O.
YP_003688130.1	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.
YP_003688131.1	L-histidinol + 2 NAD+ = L-histidine + 2 NADH
YP_003688137.1	2 L-glutamate + NADP+ <=> L-glutamine + 2-Oxoglutarate + NADPH + H+
YP_003688138.1	2 L-glutamate + 2 Oxidized ferredoxin <=> L-glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin
YP_003688139.1	transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YP_003688141.1	L-serine + 1-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O
YP_003688142.1	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.
YP_003688143.1	Chorismate + NH3 <=> Anthranilate + pyruvate + H2O and Chorismate + L-glutamine <=> Anthranilate + pyruvate + L-glutamate
YP_003688144.1	phosphoribosyl-AMP + H2O <=> 5-(5-phospho-D-ribosylaminoformimino)-1-(5- phosphoribosyl)-imidazole-4-carboxamide
YP_003688147.1	2-phospho-D-glycerate <=> 3-phospho-D-glycerate and 3-phospho-D-glyceroyl phosphate <=> 2,3-Bisphospho-D-glycerate
YP_003688156.1	glycolyse : catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. PPi-PFKs are dimeric and nonallosteric . evidenced as a heat stress protein in P.freudenreichii.
YP_003688158.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YP_003688160.1	ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine <=> ADP + 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate
YP_003688163.1	ADP-D-ribosyl-[dinitrogen reductase] + H2O <=> [Dinitrogen reductase] + ADP-D-ribose
YP_003688166.1	Catalytic activity: trehalose 6-phosphate + H2O = trehalose + phosphate. Annotated from work of Cardoso et al, 2007 (PubMed 17185556)
YP_003688167.1	Annotated from work of Cardoso et al, 2007 (PubMed 17185556) Molecular function: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity.
YP_003688168.1	2-phospho-D-glycerate <=> 3-phospho-D-glycerate and 3-phospho-D-glyceroyl phosphate <=> 2,3-Bisphospho-D-glycerate
YP_003688169.1	responsible for the conversion of adenosylcobyric acid to adenosylcobinamide or adenosylcobinamide phosphate.
YP_003688170.1	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
YP_003688171.1	Cob(I)yrinate a,c diamide + ATP <=> adenosyl cobyrinate a,c diamide + Triphosphate
YP_003688172.1	Cobyrinate + 2 L-glutamine + 2 ATP + 2 H2O <=> Cob(II)yrinate a,c diamide + 2 L-glutamate + 2 ADP + 2 Orthophosphate
YP_003688173.1	adenosyl cobinamide phosphate + GTP <=> adenosine-GDP-cobinamide + Pyrophosphate
YP_003688174.1	Cobamide coenzyme + GMP <=> adenosine-GDP-cobinamide + alpha-Ribazole
YP_003688178.1	involved in tRNA maturation
YP_003688180.1	glycine + Lipoylprotein <=> S-aminomethyldihydrolipoylprotein + CO2 . The glycine cleavage system is composed of four proteins: P, T, L and H
YP_003688181.1	The MERR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporters genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements.
YP_003688183.1	MerR, which is found in many bacterial species mediates the mercuric-dependent induction of the mercury resistance operon. In the absence of mercury merR represses transcription by binding tightly, as a dimer, to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site
YP_003688184.1	involved in signal transduction mechanisms
YP_003688185.1	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
YP_003688187.1	This family consists of several bacterial small basic proteins of around 100 residues in length. The function of this family is unknown.
YP_003688189.1	CDP-diacylglycerol + sn-glycerol 3-phosphate <=> CMP + phosphatidylglycerophosphate
YP_003688190.1	transfers one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol. transferase activity. Belongs to the glycosyltransferase 1 family.
YP_003688191.1	lipopolysaccharide core region biosynthetic process
YP_003688192.1	CDP-diacylglycerol + sn-glycerol 3-phosphate <=> CMP + phosphatidylglycerophosphate
YP_003688194.1	ATP + L-Threonine + tRNA(Thr) <=> AMP + Pyrophosphate + L-Threonyl-tRNA(Thr)
YP_003688198.1	L-methionine + thioredoxin disulfide + H(2)O <=> L-methionine (S)-S-oxide + thioredoxin # The reaction occurs in the opposite direction to that given above. Dithiothreitol can replace reduced thioredoxin. methionine sulfoxide reduction is an important process, by which cells regulate biological processes and cope with oxidative stress.
YP_003688199.1	thought to be involved in oligo-nucleotide binding, with possible roles in recognition/discrimination or editing of prolyl-tRNA.
YP_003688201.1	This is an endoribonuclease that cleaves double-stranded RNA molecules
YP_003688202.1	pyruvate + (2R)-2-Hydroxy-3-(phosphonooxy)-propanal <=> 1-deoxy-D-xylulose 5-phosphate + CO2
YP_003688205.1	Citrate = isocitrate. Binds 1 4Fe-4S cluster per subunit. Repressed by acnR
YP_003688209.1	O3-acetyl-L-serine + H2S = L-cysteine + acetate. COFACTOR: Pyridoxal phosphate Belongs to the cysteine synthase/cystathionine beta-synthase family
YP_003688210.1	acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.
YP_003688212.1	S-adenosyl-L-methionine + tRNA <=> S-adenosyl-L-homocysteine + tRNA containing thymine
YP_003688213.1	cellular component: membrane, amino acid transporter activity
YP_003688221.1	These enzymes catalyse the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars
YP_003688224.1	DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
YP_003688225.1	(R)-Pantoate + NADP+ <=> 2-Dehydropantoate + NADPH + H+
YP_003688228.1	(S)-Lactate + NAD+ <=> pyruvate + NADH + H+
YP_003688230.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
YP_003688240.1	Zeng X., Saxild H.H.; dentification and characterization of a DeoR-specific operator sequence essential for induction of dra-nupC-pdp operon expression in Bacillus subtilis J. Bacteriol. 181:1719-1727(1999).
YP_003688241.1	Composed of a catalytic glpA/B dimer and of glpC. electron transfer protein; may also function as the membrane anchor for the glpAB dimer
YP_003688242.1	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor.
YP_003688245.1	2 prime-deoxyribonucleoside diphosphate + Oxidized thioredoxin + H2O <=> ribonucleoside diphosphate + thioredoxin
YP_003688246.1	repress transcription of PF # 2791
YP_003688248.1	Represses genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of ss DNA, recA interacts with lexA causing autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair. Hydrolysis of Ala-|-Gly bond in repressor lexA. Belongs to the peptidase S24 family. Homodimer.
YP_003688249.1	helicase involved in DNA repair and perhaps also replication
YP_003688250.1	. Escherichia coli has an iron(II) transport system (feo) which may make an important contribution to the iron supply of the cell under anaerobic conditions. FeoB has been identified as part of this transport system. FeoB is a large 700-800 amino acid integral membrane. Iron transport may be ATP dependent
YP_003688251.1	LL-2,6-diaminoheptanedioate <=> meso-2,6-diaminoheptanedioate
YP_003688252.1	Isopentenyl diphosphate + tRNA <=> Pyrophosphate + tRNA containing 6-isopentenyladenosine
YP_003688256.1	RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.
YP_003688260.1	Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.
YP_003688263.1	CDP-diacylglycerol + sn-glycerol 3-phosphate <=> CMP + phosphatidylglycerophosphate
YP_003688265.1	DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it. protein located at the septum
YP_003688266.1	ATP + Thiamin monophosphate <=> ADP + Thiamin diphosphate
YP_003688269.1	Involvedin the synthesis of a cell-wall peptide . ATP + 2 D-alanine <=> ADP + Orthophosphate + D-Alanyl-D-alanine
YP_003688271.1	* (2S)-2-Isopropylmalate <=> 2-Isopropylmaleate + H2O
YP_003688272.1	(2S)-2-Isopropylmalate <=> 2-Isopropylmaleate + H2O
YP_003688273.1	This family of bacterial transcriptional regulators includes the glycerol operon regulatory protein and acetate operon repressor both of which are members of the iclR family.
YP_003688276.1	(2S)-2-Isopropylmalate + CoA <=> acetyl-CoA + 3-methyl-2-oxobutanoic acid + H2O
YP_003688277.1	Catalyzes the first reaction in the catabolism of the branched subunit amino acids leucine, isoleucine, and valine. pyridoxal-phosphate dependent enzymes
YP_003688278.1	(2R,3S)-3-Isopropylmalate + NAD+ <=> (2S)-2-Isopropyl-3-oxosuccinate + NADH + H+
YP_003688281.1	2-acetolactate + NADPH + H+ <=> 2,3-dihydroxy-3-methylbutanoate + NADP+
YP_003688282.1	2-acetolactate + CO2 <=> 2 pyruvate - amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
YP_003688283.1	2-acetolactate + CO2 <=> 2 pyruvate - amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
YP_003688294.1	Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export
YP_003688295.1	transmembran, Members of this family in E.coli are involved in export of redox proteins with a twin arginin leader motif.
YP_003688298.1	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
YP_003688299.1	Molecular function: peptidyl-prolyl cis-trans isomerase activity, Biological process: protein folding
YP_003688300.1	Molecular function: isomerase activity, Biological process: protein folding
YP_003688301.1	RNA uridine = RNA pseudouridine.
YP_003688302.1	This family of conserved bacterial proteins are thought to possibly be helix-turn-helix type transcriptional regulators
YP_003688303.1	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing smc and scpB that pull DNA away from mid-cell into both cell halves
YP_003688306.1	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids
YP_003688307.1	ADP-ribose + H2O <=> AMP + D-ribose 5-phosphate
YP_003688308.1	ATP + UTP + NH3 <=> ADP + Orthophosphate + CTP ATP + UTP + L-glutamine + H2O <=> ADP + Orthophosphate + CTP + L-glutamate
YP_003688309.1	ABC_RecN, RecN ATPase involved in DNA repair
YP_003688315.1	BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is involved in this process, however the exact function of the protein is unknown.
YP_003688316.1	sugar phosphatases of the HAD superfamily
YP_003688320.1	N-(L-arginino)succinate <=> Fumarate + L-arginine
YP_003688322.1	N2-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate. cofactor : Pyridoxal phosphate
YP_003688323.1	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate
YP_003688325.1	N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH.
YP_003688327.1	ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Pyrophosphate + L-Phenylalanyl-tRNA(Phe)
YP_003688336.1	phosphoribosyl-ATP + Pyrophosphate <=> ATP + 5-phospho-alpha-D-ribose 1-diphosphate
YP_003688337.1	phosphoribosyl-ATP + H2O <=> phosphoribosyl-AMP + Pyrophosphate
YP_003688338.1	FtsH is the only membrane-bound ATP-dependent protease universally conserved in prokaryotes. It only efficiently degrades proteins that have a low thermodynamic stability In Oenococcus oeni FtsH is involved in protection against environmental stress, and shows increased expression under heat or osmotic stress.
YP_003688339.1	ATP + L-cysteine + tRNA(Cys) <=> AMP + Pyrophosphate + L-Cysteinyl-tRNA(Cys)
YP_003688345.1	UDP diphosphate + H2O <=> UDP phosphate + Orthophosphate
YP_003688347.1	L-serine + Indoleglycerol phosphate <=> L-tryptophan + (2R)-2-Hydroxy-3-(phosphonooxy)-propanal + H2O. The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
YP_003688348.1	DNA mediated transformation
YP_003688349.1	Magnesium-chelatase is a three-component enzyme that catalyses the insertion of Mg2+ into protoporphyrin IX
YP_003688352.1	Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Endonucleolytic cleavage to 5-phosphomonoester. Manganese or magnesium as cofactor
YP_003688353.1	Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.
YP_003688354.1	highly similar to SwissProt entry RL19_PROAC from Propionibacterium acnes
YP_003688355.1	succinate + acceptor <=> fumarate + reduced acceptor
YP_003688356.1	succinate + FAD <=> FADH2 + Fumarate
YP_003688357.1	succinate + Acceptor <=> Fumarate + Reduced acceptor
YP_003688358.1	recombinant protein active on 1- naphthyl actetate and 1- naphthyl propionate
YP_003688359.1	S-adenosyl-L-methionine + tRNA <=> S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine
YP_003688364.1	SRP, The signal recognition particle (SRP) mediates the transport to or across the plasma membrane. SRP recognizes N-terminal signal sequences of newly synthesized polypeptides at the ribosome. The SRP-polypeptide complex is then targeted to the membrane by an interaction between SRP and its cognated receptor (SR).
YP_003688365.1	signal recognition particle receptor alpha subunit (docking protein), an integral membrane GTP-binding protein which ensures, in conjunction with SRP, the correct targeting of nascent secretory proteins
YP_003688367.1	Plays an important role in chromosome structure and partitioning. Essential for chromosome partition
YP_003688369.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Hydrolysis of DNA containing ring-opened 7-methylguanine residues
YP_003688371.1	This is an endoribonuclease that cleaves double-stranded RNA molecules. The cleavage can be either a single-stranded nick or double-stranded break in the RNA, depending in part upon the degree of base-pairing in the region of the cleavage site
YP_003688373.1	ATP + Pantetheine 4prime-phosphate <=> Pyrophosphate + Dephospho-CoA
YP_003688374.1	N6-adenine-specific methylase
YP_003688376.1	Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3prime to 5prime polarity. RecG unwind branched duplex DNA (Y-DNA)
YP_003688381.1	2,3,4,5-Tetrahydrodipicolinate + NAD+ <=> L-2,3-dihydrodipicolinate + NADH + H+
YP_003688382.1	Induced by several stresses and by starvation.
YP_003688384.1	ATP + FMN <=> Pyrophosphate + FAD / ATP + riboflavin <=> ADP + FMN
YP_003688385.1	Key enzyme in the regulation of glycerol uptake and metabolism, glycerol utilization; first (rate-limiting) step, ATP + glycerol = ADP + sn-glycerol 3-phosphate
YP_003688386.1	FUNCTION: glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity). # DOMAIN: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
YP_003688387.1	Uracil + D-ribose 5-phosphate <=> pseudouridine 5prime-phosphate + H2O
YP_003688388.1	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5 prime-terminal helix region of 16S rRNA
YP_003688389.1	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_003688396.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate + protein dithiol <=> 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + H2O + protein disulfide
YP_003688397.1	2-C-methyl-D-erythritol 4-phosphate + NADP+ <=> 1-deoxy-D-xylulose 5-phosphate + NADPH + H+
YP_003688399.1	CTP + phosphatidate <=> Pyrophosphate + CDP-diacylglycerol
YP_003688400.1	ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.
YP_003688405.1	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids
YP_003688406.1	formyl-L-methionyl peptide + H2O <=> methionyl peptide + formate
YP_003688407.1	Belongs to the RNA methyltransferase trmH family. RNA processing
YP_003688412.1	(3R)-3-Hydroxyacyl-ACP + NADP+ <=> 3-Oxoacyl-ACP + NADPH + H+
YP_003688414.1	Confers strong resistance to mycinamicin (MM) and tylosin (TY).
YP_003688418.1	The nif genes are responsible for nitrogen fixation. However this domain is found in bacteria that do not fix nitrogen, so it may have a broader significance in the cell than nitrogen fixation.
YP_003688420.1	The SUF system of Escherichia coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD
YP_003688428.1	Molecular function: transferase activity, Biological process: glutamine catabolic process and pyridoxal phosphate biosynthetic process
YP_003688429.1	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring. Cofactor biosynthesis, pyridoxal 5_phosphate biosynthesis-forms a complex with pdxT, induction by indole. Belongs to the pdxS/SNZ family
YP_003688431.1	D-glucose 6-phosphate + NADP+ <=> D-glucono-1,5-lactone 6-phosphate + NADPH + H+
YP_003688432.1	allosteric effector of glucose-6-phosphate dehydrogenase
YP_003688433.1	D-glucono-1,5-lactone 6-phosphate + H2O <=> 6-phospho-D-gluconate
YP_003688436.1	D-glyceraldehyde 3-phosphate = glycerone phosphate, homodimer
YP_003688438.1	D-glyceraldehyde-3-phosphate + phosphate + NAD+ = 1,3-diphosphateglycerate + NADH // D-Erythrose 4-phosphate + NAD+ + H2O <=> 4-phospho-D-erythronate + NADH + H+ et
YP_003688443.1	This family contains an ATP-binding site and could be an ATPase
YP_003688453.1	TerC has been implicated in resistance to tellurium. This protein may be involved in efflux of tellurium ions.s
YP_003688455.1	ATP + Dephospho-CoA <=> ADP + CoA
YP_003688460.1	deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
YP_003688462.1	ATP + pyruvate <=> ADP + phosphoenolpyruvate
YP_003688463.1	RNA uridine = RNA pseudouridine.
YP_003688464.1	This protein specifically catalyzes the removal of signal peptides from prolipoproteins. Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side subunits.
YP_003688470.1	The protein forms a ring at the leading edge of the cell division site
YP_003688471.1	FtsQ is one of several cell division proteins. FtsQ interacts with other Fts proteins. The precise function of FtsQ is unknown.
YP_003688472.1	cell wall formation- ATP + UDP-N-acetylmuramate + L-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine.
YP_003688473.1	UDP-N-acetylglucosamine +Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)- diphosphoundecaprenol = UDP +GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D- Ala)-diphosphoundecaprenol
YP_003688475.1	ATP + UDP-N-acetylmuramoyl-L-alanine + D-glutamate = ADP + phosphate
YP_003688477.1	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D- alanyl-D-alanine. Belongs to the murCDEF family.
YP_003688479.1	transpeptidase activity involved in the biosynthesis of septal peptidoglycan
YP_003688481.1	S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis
YP_003688482.1	belongs to the mra (murein region A) gene cluster, involved in cell wall biosynthesis and cell division
YP_003688485.1	Catalyses DNA-template-directed extension of the 3prime- end of a DNA strand by one nucleotide at a time. Cannot initiate a subunit de novo. Requires a primer, which may be DNA or RNA.
YP_003688487.1	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
YP_003688489.1	ATP-dependent DNA helicase activity
YP_003688490.1	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H.
YP_003688491.1	trans,trans-farnesyl diphosphate + isopentenyl diphosphate <=> diphosphate + geranylgeranyl diphosphate Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors
YP_003688495.1	phosphoenolpyruvate + D-Erythrose 4-phosphate + H2O <=> 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + Orthophosphate
YP_003688496.1	phosphatidate + CoA <=> 1-acyl-sn-glycerol 3-phosphate + acyl-CoA and 2,3-Dehydroacyl-CoA + 1-acyl-sn-glycerol 3-phosphate <=> CoA + phosphatidate and acyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-acyl-1-alkyl-sn-glycero-3-phosphate
YP_003688497.1	smart00563, phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities.
YP_003688498.1	membrane proteins related to metalloendopeptidases
YP_003688500.1	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides, Belongs to the cyclophilin-type PPIase family.
YP_003688502.1	acetyltransferases, including N-acetylases of ribosomal proteins
YP_003688506.1	N-(5-phospho-D-ribosyl)anthranilate + Pyrophosphate <=> Anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate
YP_003688508.1	IMP + NAD+ + H2O <=> Xanthosine 5prime-phosphate + NADH + H+
YP_003688509.1	HesB. may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which some also contain NifU-like domains pfam01106 which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation.
YP_003688512.1	Repressor of p54 sigma factor. t has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.
YP_003688516.1	S-aminomethyldihydrolipoylprotein + Tetrahydrofolate <=> dihydrolipoylprotein + 5,10-methylenetetrahydrofolate + NH3
YP_003688517.1	Succinyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [dihydrolipoyllysine-residue succinyltransferase]S-succinyldihydrolipoyllysine , glutaryl-CoA + dihydrolipoamide <=> CoA + S-glutaryldihydrolipoamide
YP_003688520.1	glutamate metabolism : ATP + L-glutamate + NH3 <=> ADP + Orthophosphate + L-glutamine , peptidoglycan biosynthesis
YP_003688522.1	Biological process: regulation of transcription, DNA-dependent , response to antibiotic
YP_003688523.1	Short-subunit dehydrogenases of various substrate specificities
YP_003688524.1	ATP + [L-glutamate:ammonia ligase (ADP-forming)] <=> Pyrophosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]
YP_003688526.1	# ATP + L-glutamate + NH3 <=> ADP + Orthophosphate + L-glutamine
YP_003688529.1	Removes the amino-terminal methionine from nascent proteins. Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. Binds 2 cobalt ions per subunit. Belongs to the peptidase M24A family
YP_003688532.1	Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family
YP_003688534.1	Citrate <=> acetate + Oxaloacetate / (3S)-Citryl-CoA <=> acetyl-CoA + Oxaloacetate
YP_003688537.1	proteins of the Mrp family are involved in stress adaptation
YP_003688539.1	L-aspartate 4-semialdehyde + pyruvate <=> L-2,3-dihydrodipicolinate + 2 H2O
YP_003688540.1	pfam01596, methyltransf_3, O-methyltransferase. Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.
YP_003688541.1	ATP + D-glucose 1-phosphate <=> Pyrophosphate + ADP-glucose
YP_003688542.1	ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase
YP_003688546.1	Possible lysine decarboxylase. The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear
YP_003688547.1	N-Succinyl-LL-2,6-diaminoheptanedioate + H2O <=> succinate + LL-2,6-diaminoheptanedioate
YP_003688548.1	Succinyl-CoA + 2,3,4,5-Tetrahydrodipicolinate + H2O <=> CoA + N-Succinyl-2-L-amino-6-oxoheptanedioate
YP_003688550.1	Molecular function: transaminase activity
YP_003688552.1	glycolate + NAD+ = glyoxylate + NADH. _ glycolate + NAD+ <=> Glyoxylate + NADH + H+
YP_003688553.1	(S)-Malate <=> Fumarate + H2O
YP_003688555.1	L-aspartate = fumarate + NH3.
YP_003688556.1	L-aspartate <=> Fumarate + NH3
YP_003688560.1	Bacterial protein of unknown function (DUF894). This family consists of several bacterial proteins, many of which are annotated as putative transmembrane transport proteins.
YP_003688561.1	Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor MarR. A large number of compounds induce transcription of mar operon, due to the compound binding to MarR and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds.
YP_003688564.1	J. Bacteriol. 177:5561-5566(1995).
YP_003688567.1	formation of cysteine from O-acetyl-serine and hydrogen sulfide. O3-acetyl-L-serine + H2S = L-cysteine + acetate.
YP_003688572.1	S-adenosyl-L-methionine + 3-demethylubiquinone-9 <=> S-adenosyl-L-homocysteine + ubiquinone-9
YP_003688574.1	ATP + D-glycerate <=> ADP + 3-phospho-D-glycerate
YP_003688575.1	peptide utilization during carbon starvation. Molecular and functional characterization of a carbon starvation gene of Escherichia coli. (J. Mol. Biol. 218:129-140(1991))
YP_003688579.1	Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family.
YP_003688580.1	ThiG, Thiazole biosynthesis protein ThiG. This family consists of several bacterial thiazole biosynthesis protein G sequences. ThiG , together with ThiF and ThiH, is proposed to be involved in the synthesis of 4-methyl-5-(b-hydroxyethyl)thiazole (THZ) which is an intermediate in the thiazole production pathway
YP_003688581.1	ThiS (ThiaminS) is a sulfur carrier protein involved in thiamin biosynthesis in bacteria. The ThiS fold, like those of two closely related proteins MoaD and Urm1, is similar to that of ubiquitin although there is little or no sequence similarity.
YP_003688583.1	2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphoethyl)-thiazole <=> Pyrophosphate + Thiamin monophosphate
YP_003688586.1	ACR3, arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism].
YP_003688592.1	acylglycerone phosphate + Long-subunit alcohol <=> O-Alkylglycerone phosphate + Long-subunit acid anion
YP_003688593.1	In the presence of glycerol 3-phosphate, this protein is thought to enhance transcription
YP_003688597.1	(R)-Lactate + NAD+ <=> pyruvate + NADH + H+
YP_003688604.1	Molecular function: transcription factor activity, Biological process: regulation of transcription, DNA-dependent
YP_003688627.1	RmuC family. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures
YP_003688628.1	No TM domain, no signal peptide
YP_003688629.1	1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + NADPH + H+ <=> Isopentenyl diphosphate + NADP+ + H2O / Dimethylallyl diphosphate + NADP+ + H2O <=> 1-Hydroxy-2-methyl-2-butenyl 4-diphosphate + NADPH + H+
YP_003688630.1	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. Exonucleolytic cleavage in either 5 prime- to 3 prime- or 3 prime- to 5 prime-direction to yield nucleoside 5 prime-phosphates.Heterooligomer composed of large and small subunits
YP_003688631.1	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. Exonucleolytic cleavage in either 5 prime- to 3 prime- or 3 prime- to 5 prime-direction to yield nucleoside 5 prime-phosphates.Heterooligomer composed of large and small subunits
YP_003688633.1	trans,trans,cis-Geranylgeranyl diphosphate + 7 Isopentenyl diphosphate <=> di-trans,poly-cis-UDP diphosphate + 7 Pyrophosphate and di-trans,poly-cis-Decaprenyl diphosphate + Isopentenyl diphosphate <=> Pyrophosphate + di-trans,poly-cis-UDP diphosphate
YP_003688637.1	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases, resulting in locked ternary complexes. Cleavage of the nascent transcript by greA or greB allows the resumption of elongation from the new 3primeterminus.
YP_003688641.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_003688642.1	peptide-L-methionine + Oxidized thioredoxin + H2O <=> peptide-L-methionine (S)-S-oxide + thioredoxin and L-methionine + Oxidized thioredoxin + H2O <=> L-methionine (S)-S-oxide + thioredoxin
YP_003688650.1	methylpurine-DNA glycosylase is a base excision-repair protein. It is responsible for the hydrolysis of the deoxyribose N-glycosidic bond, excising 3-methyladenine and 3-methylguanine from damaged DNA.
YP_003688657.1	2-phospho-D-glycerate = phosphoenolpyruvate + H2O, homodimer, cofactor : magnesium
YP_003688660.1	Guanosine 3prime-diphosphate 5prime-triphosphate + H2O <=> Guanosine 3prime,5prime-bis(diphosphate) + Orthophosphate
YP_003688663.1	2-phospho-D-glycerate = phosphoenolpyruvate + H2O, homodimer, cofactor : magnesium
YP_003688666.1	Necessary for strand-specific repair. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognized by TRCF which releases RNAP and the truncated transcript; the TCRF may replace RNAP at the lesion site and then recruit the uvrA/B/C repair system
YP_003688668.1	N-Substituted aminoacyl-tRNA + H2O <=> N-Substituted amino acid + tRNA
YP_003688670.1	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18
YP_003688671.1	ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate
YP_003688672.1	UTP + N-acetyl-D-glucosamine 1-phosphate <=> Pyrophosphate + UDP-N-acetyl-D-glucosamine and UTP + N-acetyl-alpha-D-glucosamine 1-phosphate <=> Pyrophosphate + UDP-N-acetyl-D-glucosamine
YP_003688674.1	carbamoyl phosphate + L-aspartate <=> Orthophosphate + N-carbamoyl-L-aspartate
YP_003688676.1	4-(Cytidine 5prime-diphospho)-2-C-methyl-D-erythritol + ATP <=> 2-phospho-4-(cytidine 5prime-diphospho)-2-C-methyl-D-erythritol + ADP
YP_003688677.1	Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3prime-end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance
YP_003688678.1	TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity.
YP_003688679.1	pfam00590, TP_methylase, Tetrapyrrole (Corrin/Porphyrin) methylases. This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function. This family includes the methylase Dipthine synthase.
YP_003688686.1	ATP + D-Galactose <=> ADP + alpha-D-Galactose 1-phosphate
YP_003688687.1	The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents
YP_003688688.1	CRCB is a putative integral membrane protein possibly involved in chromosome condensation. Over expression in E. Coli also leads to camphor resistance.
YP_003688691.1	L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH. Homohexamer (By similarity). Belongs to the Glu/Leu/Phe/Val dehydrogenases family. Evidenced as a heat stress proetin in P. freudenreichii
YP_003688696.1	Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response
YP_003688700.1	Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
YP_003688708.1	No TM domain, no signal peptide
YP_003688710.1	arabinose operon control protein
YP_003688711.1	Binds to three inverted repeats (IR1-IR3) in the promoter region of the dnaK operon
YP_003688712.1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins
YP_003688713.1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with dnaK
YP_003688714.1	Belongs to the heat shock protein 70 family. Acts as a chaperone. Several 70 to 75 kda Hsp70 chaperones are expressed as disctinct heat shock proteins
YP_003688722.1	The protein has been identified by proteomics as a 94 kDa protein induced by heat, bile salts and acid stress
YP_003688724.1	Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions
YP_003688727.1	acetyl-CoA + ribosomal-protein L-alanine <=> CoA + ribosomal-protein N-acetyl-L-alanine
YP_003688728.1	Involved in the biosynthesis of a demolybdo-cofactor (molybdopterin), necessary for molybdo-enzymes
YP_003688729.1	catalyses the interchange of 5-formyltetrahydrofolate (5-FTHF) to 5-10-methenyltetrahydrofolate, this requires ATP and Mg2+.Dayan A, Bertrand R, Beauchemin M, Chahla D, Mamo A, Filion M, 5-FTHF is used in chemotherapy where it is clinically known as Leucovorin.
YP_003688733.1	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
YP_003688735.1	UTP + D-glucose 1-phosphate <=> Pyrophosphate + UDP-glucose
YP_003688737.1	an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond.isochorismatase is part of the phenazine biosynthesis pathway. Phenazines are antimicrobial compounds that provide the competitive advantage for certain bacteria.
YP_003688738.1	recombinant protein active on 1- naphthyl actetate and 1- naphthyl propionate
YP_003688741.1	thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. Some members with only the active site are not separated from the noise. protein dithiol + NAD+ <=> protein disulfide + NADH + H+
YP_003688748.1	RNA-binding domain that functions as a RNA-chaperone in bacteria
YP_003688758.1	several slp were identified in P. freudenreichii
YP_003688759.1	hydrolyse a wide range of organic pyrophosphates, polyphosphates, nucleotide sugars and RNA caps, with varying degrees of substrate specificity. MicrotT, have the ability to degrade potentially mutagenic, oxidised nucleotides while others control the levels of metabolic intermediates and signalling compounds. McLennan AG cell Mol Life Sci. 2006 Jan;63(2):123-43
YP_003688760.1	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. groL1 and groL2 are expressed as 2 distinct heat shock proteins
YP_003688762.1	D-Mannose 6-phosphate <=> D-Fructose 6-phosphate and D-Mannose 6-phosphate <=> beta-D-Fructose 6-phosphate
YP_003688769.1	L-serine <=> pyruvate + NH3 / alpha-amino acid <=> 2-Oxo acid + NH3 L-serine <=> 2-aminoacrylate + H2O /
YP_003688780.1	ATP + L-cysteine + tRNA(Cys) <=> AMP + Pyrophosphate + L-Cysteinyl-tRNA(Cys)
YP_003688785.1	L-asparagine + H2O = L-aspartate + NH3.
YP_003688786.1	* 5,10-methylenetetrahydrofolate + glycine + H2O <=> Tetrahydrofolate + L-serine
YP_003688787.1	regulated by CarD
YP_003688788.1	transcription regulated by CarD, 2-C-methyl-D-erythritol 4-phosphate + CTP <=> 4-(Cytidine 5 prime-diphospho)-2-C-methyl-D-erythritol + Pyrophosphate
YP_003688789.1	probably regulates isp genes
YP_003688790.1	Probably forms part of a two-component regulatory system regX3/senX3
YP_003688791.1	ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
YP_003688795.1	L-serine + NADP+ <=> 2-aminomalonate semialdehyde + NADPH + H+
YP_003688796.1	operon (5S +12S +1.3S). Expressed in the presence of substrate. Overexpressed in response to stress.
YP_003688798.1	operon (5S +12S +1.3S). Expressed in the presence of substrate. Overexpressed in response to stress.
YP_003688799.1	operon transcarboxylase (5S + 12S +1.3S) The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1.3S subunit to pyruvate to form oxaloacetate and 1.3S biotin. Expressed in the presence of substrate. Overexpressed in response to stress.
YP_003688800.1	(S)-4-amino-5-oxopentanoate = 5-aminolevulinate Porphyrin biosynthesis by the C5 pathway; second step. Homodimer. cofactor : Pyridoxal phosphate
YP_003688802.1	involved in porphyrin synthesis
YP_003688803.1	porphyrin biosynthese. 2 5-aminolevulinate = porphobilinogen + 2 H2O cofactor : zinc
YP_003688804.1	Catalyzes the ferrous insertion into protoporphyrin IX. Protoporphyrin + Fe(2+) = protoheme + 2 H(+).
YP_003688805.1	Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Porphyrin biosynthesis; penultimate step. Protoporphyrinogen-IX + 1.5 O2 = protoporphyrin-IX + 3 H2O. Homodimer. Cofactor : 1 FAD per dimer
YP_003688807.1	Uroporphyrinogen III <=> Coproporphyrinogen III + 4 CO2 and Uroporphyrinogen I <=> Coproporphyrinogen I + 4 CO2
YP_003688808.1	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH3. Cofactor : binds 1 dipyrromethane group covalently
YP_003688809.1	L-glutamyl-tRNA(Glu) + NADPH + H+ <=> (S)-4-amino-5-oxopentanoate + tRNA(Glu) + NADP+
YP_003688810.1	ATP + L-aspartate + L-glutamine + H2O <=> AMP + Pyrophosphate + L-asparagine + L-glutamate
YP_003688813.1	carbohydrate degradation, myo-inositol degradation to acetyl-CoA
YP_003688815.1	carbohydrate degradation, myo-inositol degradation to acetyl-CoA
YP_003688816.1	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
YP_003688818.1	carbohydrate degradation, myo-inositol degradation to acetyl-CoA
YP_003688820.1	carbohydrate degradation, myo-inositol degradation to acetyl-CoA
YP_003688821.1	carbohydrate degradation, myo-inositol degradation to acetyl-CoA
YP_003688822.1	* 3-Oxopropanoate + CoA + NAD+ <=> acetyl-CoA + CO2 + NADH + H+
YP_003688823.1	transporter in the P.freudenreichii iol operon
YP_003688827.1	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate, cofactor : zinc
YP_003688831.1	The members of this family are related to the LemA protein. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain
YP_003688832.1	Orotidine 5prime-phosphate + Pyrophosphate <=> Orotate + 5-phospho-alpha-D-ribose 1-diphosphate
YP_003688833.1	transpeptidase of Gram-positive bacteria, cleaves surface proteins at the LPXTG motif between Thr and Gly and catalyzes the formation of an amide bond between the carboxyl group of Thr and the amino group of cell-wall crossbridges.
YP_003688835.1	S-adenosylmethioninamine + Putrescine <=> 5prime-methylthioadenosine + Spermidine / S-adenosylmethioninamine + Spermidine <=> 5prime-methylthioadenosine + Spermine
YP_003688836.1	The OPT family of oligopeptide transporters is distinct from the ABC pfam00005 and PTR pfam00854 transporter families.
YP_003688837.1	The protein has been identified by proteomics as a 95 kDa protein induced by various stresses.several 90 to 100 kda clp chaperones are expressed as disctinct heat shock proteins
YP_003688838.1	5-aminolevulinate <=> (S)-4-amino-5-oxopentanoate
YP_003688840.1	GTP + IMP + L-aspartate = GDP + phosphate + N6-(1,2-dicarboxyethyl)-AMP
YP_003688842.1	(S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH
YP_003688843.1	nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base.
YP_003688845.1	Could be involved in copper resistance. May have oxidase activity
YP_003688849.1	homopolysaccharide synthesis - homology detected with tts, responsible of capsular synthesis of streptococcus pneumoniae
YP_003688851.1	The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyses the polymerisation of murein glycan subunits.
YP_003688854.1	Inhibits protein synthesis by cleavage of mRNA
YP_003688859.1	HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation across the cell membrane.
YP_003688866.1	thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. Some members with only the active site are not separated from the noise
YP_003688868.1	involved in signal transduction mechanisms
YP_003688872.1	ATP + protein <=> ADP + phosphoprotein
YP_003688874.1	ATP + D-Galactose <=> ADP + alpha-D-Galactose 1-phosphate
YP_003688876.1	Fe2+ transport system protein B. Molecular function: GTP binding, iron ion binding. cellular component: integral to membrane
YP_003688877.1	This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.
YP_003688881.1	These enzymes are Zn dependent and catalyze the deamination of nucleosides. The functional enzyme is a homodimer. Cytosine deaminase catalyzes the deamination of cytosine to uracil and ammonia and is a member of the pyrimidine salvage pathway.
YP_003688883.1	UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate. Belongs to the UPRTase family. Pyrimidine salvage pathway.
YP_003688891.1	glycine + Tetrahydrofolate + NAD+ <=> 5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH + H+
YP_003688895.1	a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not in archea; beta barrel-like fold structure; forms homodimers in which two surface cavities serve as the active site for tRNA binding.
YP_003688897.1	inositol 1-phosphate <=> D-glucose 6-phosphate. inositol-1-phosphate catalyses the conversion of glucose-6- phosphate to inositol-1-phosphate, which is then dephosphorylated to inositol. inositol phosphates play an important role in signal transduction.
YP_003688899.1	Benzoate degradation via hydroxylation 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate <=> 2-Oxo-2,3-dihydrofuran-5-acetate + CO2
YP_003688902.1	ATP + Pyrophosphate <=> ADP + Triphosphate
YP_003688904.1	The complex is composed of two ATP-binding proteins (pstB), two transmembrane proteins (pstC and pstA) and a solute-binding protein (pstS)
YP_003688905.1	The complex is composed of two ATP-binding proteins (pstB), two transmembrane proteins (pstC and pstA) and a solute-binding protein (pstS)
YP_003688906.1	The complex is composed of two ATP-binding proteins (pstB), two transmembrane proteins (pstC and pstA) and a solute-binding protein (pstS)
YP_003688907.1	TC3.A.1.7 The complex is composed of two ATP-binding proteins (pstB), two transmembrane proteins (pstC and pstA) and a solute-binding protein (pstS)
YP_003688908.1	arsenate ion + glutaredoxin <=> arsenite + glutaredoxin disulfide
YP_003688916.1	Hydroxymethylbilane <=> uroporphyrinogen-III + H(2)O
YP_003688918.1	L-proline + NAD+ <=> (S)-1-Pyrroline-5-carboxylate + NADH + H+
YP_003688919.1	L-aspartate 4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH.
YP_003688925.1	Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged.
YP_003688928.1	locus ABC transporter PF #2140, 2141 et 2475
YP_003688930.1	Chorismate + NH3 <=> Anthranilate + pyruvate + H2O
YP_003688932.1	3-Dehydroquinate <=> 3-Dehydroshikimate + H2O
YP_003688934.1	Belongs to the clpA/clpB family. ClpC subfamily. The protein has been identified by proteomics as a 99 kDa protein induced by heat.Several 90 to 100 kda clp chaperones are expressed as disctinct heat shock proteins
YP_003688937.1	2-amino-4-hydroxy-6-(D-erythro-1,2, 3-trihydroxypropyl)-7, 8-dihydropteridine <=> glycolaldehyde + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine
YP_003688938.1	2-amino-7, 8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine + 4-aminobenzoate <=> Pyrophosphate + dihydropteroate / 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + 4-aminobenzoate <=> dihydropteroate + H2O
YP_003688940.1	catalyzes the conversion of GTP into dihydroneopterin triphosphate. The enzyme product is the precursor of tetrahydrofolate
YP_003688942.1	Guanine and 6-mercaptopurine can replace hypoxanthine.
YP_003688945.1	Molecular function: serine carboxypeptidase activity
YP_003688946.1	Pyrophosphate + H2O <=> 2 Orthophosphate
YP_003688952.1	In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. Homotrimer
YP_003688953.1	RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2
YP_003688955.1	permease that is involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine
YP_003688961.1	deoxynucleoside triphosphate + DNA <=> Pyrophosphate + DNA
YP_003688962.1	ATP + dTMP <=> ADP + dTDP and ATP + dUMP <=> ADP + dUDP
YP_003688968.1	electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. Heterotrimeric enzyme composed of a catalytic heterodimer (DmsAB) and a membrane anchor protein (DmsC).
YP_003688979.1	ype II/IV secretion system protein. This family contains both type II and type IV pathway secretion proteins from bacteria.
YP_003688982.1	Na_H_antiport_1, Na+/H+ antiporter 1. This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyse the exchange of H+ for Na+ in a manner that is highly dependent on the pH.
YP_003688991.1	Proton-dependent transporter. May mediate the efflux of lincomycin
YP_003688992.1	Acceptor + NADPH + H+ <=> Reduced acceptor + NADP+
YP_003688998.1	2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphoethyl)-thiazole <=> Pyrophosphate + Thiamin monophosphate
YP_003688999.1	Actively transports glucose into cells by Na(+) cotransport
YP_003689003.1	H(+)-stimulated, highly selective, manganese uptake system
YP_003689006.1	VWA, von Willebrand factor (vWF) type A domain; VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.
YP_003689010.1	AbiF, Abortive infection bacteriophage resistance protein [Defense mechanisms].
YP_003689030.1	ATP + protein <=> ADP + phosphoprotein
YP_003689037.1	Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis.
YP_003689038.1	deoxynucleoside triphosphate + DNA <=> Pyrophosphate + DNA
YP_003689046.1	Hg + NADP+ + H+ <=> Hg2+ + NADPH
YP_003689055.1	Biological process: DNA methylation, N-methyltransferase activity. S-adenosyl-L-methionine + DNA adenine <=> S-adenosyl-L-homocysteine + DNA 6-methylaminopurine
YP_003689056.1	highly similar to Q6A7B6_PROAC from Propionibacterium acnes
YP_003689060.1	2 6,7-Dimethyl-8-(1-D-ribityl)lumazine <=> riboflavin + 4-(1-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine
YP_003689061.1	GTP + 3 H2O <=> formate + 2,5-diamino-6-(5p-phosphoribosylamino)-4-pyrimidineone + Pyrophosphate
YP_003689062.1	2 6,7-Dimethyl-8-(1-D-ribityl)lumazine <=> riboflavin + 4-(1-D-Ribitylamino)-5-amino-2,6-dihydroxypyrimidine
YP_003689063.1	2, 5-diamino-6-(5-phosphoribosylamino)-4-pyrimidineone + H2O <=> 5-amino-6-(5-phosphoribosylamino)uracil + NH3 / 5-amino-6-(5-phosphoribitylamino)uracil + NADP+ <=> 5-amino-6-(5-phosphoribosylamino)uracil + NADPH + H+
YP_003689066.1	Amylose <=> 1,4-alpha-D-glucan
YP_003689069.1	NADH + acceptor <=> NAD(+) + reduced acceptor
YP_003689070.1	NADPH + NAD+ <=> NADP+ + NADH
YP_003689072.1	DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein.
YP_003689078.1	Hydrogen sulfide + 6 oxidized ferredoxin + 3 H2O = sulfite + 6 reduced ferredoxin + 6 H+.Binds 1 siroheme per subunit Binds 1 4Fe-4S cluster per subunit
YP_003689080.1	ATP + sulfate = diphosphate + adenylyl sulfate
YP_003689087.1	Nitrite + Acceptor <=> Nitrate + Reduced acceptor
YP_003689089.1	Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group, Heterodimer of 2 moaD subunits and 2 moaE subunits
YP_003689090.1	involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism].
YP_003689092.1	Involved in the biosynthesis of a demolybdo-cofactor (molybdopterin), necessary for molybdo-enzymes. Seems to be involved in a step of activation of molybdenum in the form of thiomolybdenum.
YP_003689093.1	Together with moaA, is involved in the conversion of a guanosine derivative (5-GTP) into molybdopterin precursor Z
YP_003689094.1	Mo-molybdopterin cofactor biosynthetic process
YP_003689097.1	D-amino acid + H2O + Acceptor <=> 2-Oxo acid + NH3 + Reduced acceptor
YP_003689134.1	arsenic resistance
YP_003689137.1	promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MERR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site.
YP_003689139.1	ATP + xanthosine 5 prime-phosphate + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate ; inhibiteur Psicofuranin
YP_003689140.1	ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.
YP_003689149.1	This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues.
YP_003689151.1	ATP + Ribulose <=> ADP + D-Ribulose 5-phosphate
YP_003689155.1	arabinose operon
YP_003689156.1	signal peptide (SignalP) transmembrane (TM HMM)
YP_003689159.1	transcription regulation of arabinose/xylulose/ribulose operon ?
YP_003689160.1	D-glyceraldehyde 3-phosphate = glycerone phosphate, homodimer
YP_003689164.1	proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site.
YP_003689177.1	glycogen debranching enzyme activity, hydrolase activity, hydrolyzing O-glycosyl compounds
YP_003689185.1	integrase core domain. integrase mediates integration of a DNA copy of the viral genome into the host chromosome.
YP_003689189.1	This protein catalyzes the inversion of a 3000-bp segment of phage DNA. The inversion results in a modification of the 3prime-end of the tail fiber gene and alters the host specificity.
YP_003689192.1	Belongs to the small heat shock protein (HSP20) family.These seem to act as chaperones that can protect other proteins against heat-induced denaturation and aggregation. Hsp20 proteins seem to form large heterooligomeric aggregates. Structurally, this family is characterized by the presence of a conserved C-terminal domain of about 100 residues.
YP_003689193.1	Belongs to the small heat shock protein (HSP20) family.These seem to act as chaperones that can protect other proteins against heat-induced denaturation and aggregation. Hsp20 proteins seem to form large heterooligomeric aggregates. Structurally, this family is characterized by the presence of a conserved C-terminal domain of about 100 residues.
YP_003689197.1	Uptake of D-glucarate
YP_003689200.1	O-phospho-4-hydroxy-L-threonine + NAD+ <=> 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+ (Cofactor biosynthesis; pyridoxine 5-phosphate biosynthesis; pyridoxine 5-phosphate from D-erythrose 4-phosphate: step 4/5.)
YP_003689202.1	L-cystathionine + H2O = L-homocysteine + NH3 + pyruvate.
YP_003689203.1	Can use both glutamine or ammonia as a nitrogen source (By similarity). ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.. Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (glutamine route): step 1/1.
YP_003689204.1	PadR, transcriptional regulator PadR-like family.
YP_003689210.1	Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is also called pyrazinamidase, because in converts the tuberculosis drug pyrazinamide (PZA) into its active form pyrazinoic acid (POA). Nicotinamide + H2O <=> Nicotinate + NH3
YP_003689212.1	Hydroxypyruvate <=> 2-Hydroxy-3-oxopropanoate
YP_003689214.1	ATP + Long-subunit carboxylate + CoA <=> AMP + Pyrophosphate + acyl-CoA and ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Pyrophosphate
YP_003689215.1	These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites.
YP_003689225.1	(R)-Pantoate + NADP+ <=> 2-Dehydropantoate + NADPH + H+
YP_003689230.1	The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain
YP_003689231.1	recombinant protein active on 1- naphthyl actetate and 1- naphthyl propionate
YP_003689232.1	glycerophosphodiester + H2O <=> Alcohol + sn-glycerol 3-phosphate
YP_003689233.1	Sugar phosphate permease
YP_003689236.1	myo-inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+
YP_003689238.1	thiosulfate + Cyanide <=> Sulfite + thiocyanate
YP_003689239.1	L-glutamate <=> 4-aminobutanoate + CO2 L-aspartate <=> beta-alanine + CO2
YP_003689249.1	Annotation inferred by similarity with protein ybdl E coli (swiss prot P77806)
YP_003689265.1	Inorganic pyrophosphatase (EC:3.6.1.1) (PPase) [1, 2] is the enzyme responsible for the hydrolysis of pyrophosphate (PPi) which is formed principally as the product of the many biosynthetic reactions that utilise ATP
YP_003689266.1	This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyses the disproportionation of chlorite into chloride and oxygen.
YP_003689268.1	Isochorismate + H2O <=> 2,3-dihydro-2,3-dihydroxybenzoate + pyruvate
YP_003689274.1	Starch + H2O <=> Dextrin + Starch
YP_003689275.1	alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly
YP_003689290.1	acetyl-CoA <=> Long-subunit acyl-CoA
YP_003689292.1	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide, 2 H2O2 = O2 + 2 H2O , Heme group, cofactor NADPH, Homotetramer, Cytoplasm, catalase family.
YP_003689303.1	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate
YP_003689305.1	publication in : nucleotide sequence, expression and transcriptional analysis of the Corynebacterium glutamicum gltA gene encoding citrate synthase. Microbiology 140:1817-1828(1994) - acetyl-CoA + H2O + oxaloacetate = citrate + CoA. Weakly inhibited by ATP. Homohexamer. Citrate synthase is found in nearly all cells capable of oxidative metabolism.
YP_003689326.1	thioredoxin. thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond.
YP_003689327.1	Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli.
YP_003689329.1	Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication
YP_003689330.1	ATPases involved in chromosome partitioning
YP_003689333.1	Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory subunit complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex.