-- dump date   	20140620_001535
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1157951000001	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
1157951000002	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1157951000003	non-specific DNA binding site [nucleotide binding]; other site
1157951000004	salt bridge; other site
1157951000005	sequence-specific DNA binding site [nucleotide binding]; other site
1157951000006	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
1157951000007	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
1157951000008	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1157951000009	Zonular occludens toxin (Zot); Region: Zot; cl17485
1157951000010	Zonular occludens toxin (Zot); Region: Zot; cl17485
1157951000011	Helix-destabilising protein; Region: Phage_DNA_bind; pfam02303
1157951000012	Replication initiation factor; Region: Rep_trans; pfam02486
1157951000013	DNA replication initiation protein; Region: PHA00202
1157951000014	Replication initiation factor; Region: Rep_trans; pfam02486
1157951000015	Domain of unknown function (DUF4365); Region: DUF4365; pfam14280
1157951000016	potential frameshift: common BLAST hit: gi|148826860|ref|YP_001291613.1| putative phage-like secreted protein
1157951000017	Zonular occludens toxin (Zot); Region: Zot; cl17485
1157951000018	Uncharacterized small protein (DUF2158); Region: DUF2158; cl02293
1157951000019	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951000020	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951000021	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951000022	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951000023	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951000024	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951000025	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951000026	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951000027	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951000028	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951000029	Fimbrial protein; Region: Fimbrial; pfam00419
1157951000030	Fimbrial protein; Region: Fimbrial; pfam00419
1157951000031	Fimbrial protein; Region: Fimbrial; pfam00419
1157951000032	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951000033	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951000034	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951000035	hypothetical protein; Provisional; Region: PRK11622
1157951000036	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1157951000037	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1157951000038	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951000039	dimer interface [polypeptide binding]; other site
1157951000040	conserved gate region; other site
1157951000041	putative PBP binding loops; other site
1157951000042	ABC-ATPase subunit interface; other site
1157951000043	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1157951000044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951000045	dimer interface [polypeptide binding]; other site
1157951000046	conserved gate region; other site
1157951000047	putative PBP binding loops; other site
1157951000048	ABC-ATPase subunit interface; other site
1157951000049	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1157951000050	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951000051	Walker A/P-loop; other site
1157951000052	ATP binding site [chemical binding]; other site
1157951000053	Q-loop/lid; other site
1157951000054	ABC transporter signature motif; other site
1157951000055	Walker B; other site
1157951000056	D-loop; other site
1157951000057	H-loop/switch region; other site
1157951000058	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1157951000059	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1157951000060	active site
1157951000061	catalytic site [active]
1157951000062	MarR family; Region: MarR_2; pfam12802
1157951000063	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1157951000064	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1157951000065	nucleotide binding site [chemical binding]; other site
1157951000066	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1157951000067	nudix motif; other site
1157951000068	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
1157951000069	RibD C-terminal domain; Region: RibD_C; cl17279
1157951000070	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1157951000071	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951000072	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
1157951000073	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1157951000074	putative active site [active]
1157951000075	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951000076	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
1157951000077	Walker A/P-loop; other site
1157951000078	ATP binding site [chemical binding]; other site
1157951000079	Q-loop/lid; other site
1157951000080	ABC transporter signature motif; other site
1157951000081	Walker B; other site
1157951000082	D-loop; other site
1157951000083	H-loop/switch region; other site
1157951000084	AAA domain; Region: AAA_17; pfam13207
1157951000085	malonic semialdehyde reductase; Provisional; Region: PRK10538
1157951000086	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1157951000087	putative NAD(P) binding site [chemical binding]; other site
1157951000088	homodimer interface [polypeptide binding]; other site
1157951000089	homotetramer interface [polypeptide binding]; other site
1157951000090	active site
1157951000091	Protein of unknown function (DUF1283); Region: DUF1283; cl11644
1157951000092	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1157951000093	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1157951000094	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1157951000095	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1157951000096	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951000097	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951000098	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1157951000099	dimerization interface [polypeptide binding]; other site
1157951000100	substrate binding pocket [chemical binding]; other site
1157951000101	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1157951000102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951000103	putative substrate translocation pore; other site
1157951000104	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1157951000105	DNA replication terminus site-binding protein (Ter protein); Region: Ter; cl11502
1157951000106	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1157951000107	Class II fumarases; Region: Fumarase_classII; cd01362
1157951000108	active site
1157951000109	tetramer interface [polypeptide binding]; other site
1157951000110	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1157951000111	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1157951000112	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1157951000113	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1157951000114	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1157951000115	adenosine deaminase; Provisional; Region: PRK09358
1157951000116	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1157951000117	active site
1157951000118	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1157951000119	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1157951000120	putative oxidoreductase; Provisional; Region: PRK11579
1157951000121	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1157951000122	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1157951000123	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1157951000124	electron transport complex protein RsxA; Provisional; Region: PRK05151
1157951000125	electron transport complex protein RnfB; Provisional; Region: PRK05113
1157951000126	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1157951000127	Putative Fe-S cluster; Region: FeS; cl17515
1157951000128	4Fe-4S binding domain; Region: Fer4; pfam00037
1157951000129	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
1157951000130	SLBB domain; Region: SLBB; pfam10531
1157951000131	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1157951000132	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1157951000133	electron transport complex protein RnfG; Validated; Region: PRK01908
1157951000134	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1157951000135	endonuclease III; Provisional; Region: PRK10702
1157951000136	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1157951000137	minor groove reading motif; other site
1157951000138	helix-hairpin-helix signature motif; other site
1157951000139	substrate binding pocket [chemical binding]; other site
1157951000140	active site
1157951000141	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1157951000142	exoribonuclease II; Provisional; Region: PRK05054
1157951000143	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1157951000144	RNB domain; Region: RNB; pfam00773
1157951000145	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1157951000146	lipoprotein; Provisional; Region: PRK10540
1157951000147	translation initiation factor Sui1; Validated; Region: PRK06824
1157951000148	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1157951000149	putative rRNA binding site [nucleotide binding]; other site
1157951000150	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1157951000151	active site
1157951000152	dimer interface [polypeptide binding]; other site
1157951000153	tetratricopeptide repeat protein; Provisional; Region: PRK11788
1157951000154	Protein of unknown function (DUF1049); Region: DUF1049; cl01539
1157951000155	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1157951000156	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1157951000157	active site
1157951000158	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1157951000159	dimerization interface [polypeptide binding]; other site
1157951000160	active site
1157951000161	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1157951000162	dimer interface [polypeptide binding]; other site
1157951000163	active site
1157951000164	Schiff base residues; other site
1157951000165	aconitate hydratase; Validated; Region: PRK09277
1157951000166	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1157951000167	substrate binding site [chemical binding]; other site
1157951000168	ligand binding site [chemical binding]; other site
1157951000169	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1157951000170	substrate binding site [chemical binding]; other site
1157951000171	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1157951000172	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951000173	The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413
1157951000174	substrate binding site [chemical binding]; other site
1157951000175	dimerization interface [polypeptide binding]; other site
1157951000176	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1157951000177	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1157951000178	active site
1157951000179	Zn binding site [ion binding]; other site
1157951000180	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1157951000181	E-class dimer interface [polypeptide binding]; other site
1157951000182	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1157951000183	P-class dimer interface [polypeptide binding]; other site
1157951000184	active site
1157951000185	Cu2+ binding site [ion binding]; other site
1157951000186	Zn2+ binding site [ion binding]; other site
1157951000187	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1157951000188	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1157951000189	active site
1157951000190	metal binding site [ion binding]; metal-binding site
1157951000191	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1157951000192	domain I; other site
1157951000193	DNA binding groove [nucleotide binding]
1157951000194	phosphate binding site [ion binding]; other site
1157951000195	domain II; other site
1157951000196	domain III; other site
1157951000197	nucleotide binding site [chemical binding]; other site
1157951000198	catalytic site [active]
1157951000199	domain IV; other site
1157951000200	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1157951000201	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1157951000202	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1157951000203	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1157951000204	active site
1157951000205	metal binding site [ion binding]; metal-binding site
1157951000206	Protein of unknown function (DUF2498); Region: DUF2498; cl11671
1157951000207	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1157951000208	putative inner membrane peptidase; Provisional; Region: PRK11778
1157951000209	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1157951000210	tandem repeat interface [polypeptide binding]; other site
1157951000211	oligomer interface [polypeptide binding]; other site
1157951000212	active site residues [active]
1157951000213	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1157951000214	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1157951000215	NAD(P) binding site [chemical binding]; other site
1157951000216	active site
1157951000217	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1157951000218	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
1157951000219	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1157951000220	homodimer interface [polypeptide binding]; other site
1157951000221	Walker A motif; other site
1157951000222	ATP binding site [chemical binding]; other site
1157951000223	hydroxycobalamin binding site [chemical binding]; other site
1157951000224	Walker B motif; other site
1157951000225	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1157951000226	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1157951000227	RNA binding surface [nucleotide binding]; other site
1157951000228	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1157951000229	probable active site [active]
1157951000230	hypothetical protein; Provisional; Region: PRK11630
1157951000231	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1157951000232	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1157951000233	active site
1157951000234	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1157951000235	anthranilate synthase component I; Provisional; Region: PRK13564
1157951000236	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1157951000237	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1157951000238	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1157951000239	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1157951000240	glutamine binding [chemical binding]; other site
1157951000241	catalytic triad [active]
1157951000242	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1157951000243	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1157951000244	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1157951000245	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1157951000246	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1157951000247	active site
1157951000248	ribulose/triose binding site [chemical binding]; other site
1157951000249	phosphate binding site [ion binding]; other site
1157951000250	substrate (anthranilate) binding pocket [chemical binding]; other site
1157951000251	product (indole) binding pocket [chemical binding]; other site
1157951000252	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1157951000253	active site
1157951000254	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1157951000255	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1157951000256	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951000257	catalytic residue [active]
1157951000258	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1157951000259	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1157951000260	substrate binding site [chemical binding]; other site
1157951000261	active site
1157951000262	catalytic residues [active]
1157951000263	heterodimer interface [polypeptide binding]; other site
1157951000264	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
1157951000265	BON domain; Region: BON; pfam04972
1157951000266	outer membrane protein W; Provisional; Region: PRK10959
1157951000267	hypothetical protein; Provisional; Region: PRK02868
1157951000268	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1157951000269	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1157951000270	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1157951000271	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1157951000272	intracellular septation protein A; Reviewed; Region: PRK00259
1157951000273	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1157951000274	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1157951000275	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1157951000276	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1157951000277	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1157951000278	putative active site [active]
1157951000279	catalytic site [active]
1157951000280	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1157951000281	putative active site [active]
1157951000282	catalytic site [active]
1157951000283	Protein of unknown function, DUF440; Region: DUF440; cl11472
1157951000284	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1157951000285	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1157951000286	Walker A/P-loop; other site
1157951000287	ATP binding site [chemical binding]; other site
1157951000288	Q-loop/lid; other site
1157951000289	ABC transporter signature motif; other site
1157951000290	Walker B; other site
1157951000291	D-loop; other site
1157951000292	H-loop/switch region; other site
1157951000293	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1157951000294	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1157951000295	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1157951000296	Walker A/P-loop; other site
1157951000297	ATP binding site [chemical binding]; other site
1157951000298	Q-loop/lid; other site
1157951000299	ABC transporter signature motif; other site
1157951000300	Walker B; other site
1157951000301	D-loop; other site
1157951000302	H-loop/switch region; other site
1157951000303	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1157951000304	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1157951000305	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1157951000306	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951000307	dimer interface [polypeptide binding]; other site
1157951000308	conserved gate region; other site
1157951000309	ABC-ATPase subunit interface; other site
1157951000310	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1157951000311	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951000312	dimer interface [polypeptide binding]; other site
1157951000313	conserved gate region; other site
1157951000314	putative PBP binding loops; other site
1157951000315	ABC-ATPase subunit interface; other site
1157951000316	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1157951000317	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1157951000318	peptide binding site [polypeptide binding]; other site
1157951000319	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1157951000320	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1157951000321	peptide binding site [polypeptide binding]; other site
1157951000322	hypothetical protein; Provisional; Region: PRK11111
1157951000323	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1157951000324	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1157951000325	putative catalytic cysteine [active]
1157951000326	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1157951000327	putative active site [active]
1157951000328	metal binding site [ion binding]; metal-binding site
1157951000329	thymidine kinase; Provisional; Region: PRK04296
1157951000330	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1157951000331	ATP binding site [chemical binding]; other site
1157951000332	Walker A motif; other site
1157951000333	Walker B motif; other site
1157951000334	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1157951000335	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1157951000336	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1157951000337	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1157951000338	active site
1157951000339	tetramer interface; other site
1157951000340	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951000341	active site
1157951000342	response regulator of RpoS; Provisional; Region: PRK10693
1157951000343	phosphorylation site [posttranslational modification]
1157951000344	intermolecular recognition site; other site
1157951000345	dimerization interface [polypeptide binding]; other site
1157951000346	hypothetical protein; Provisional; Region: PRK01617
1157951000347	SEC-C motif; Region: SEC-C; pfam02810
1157951000348	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1157951000349	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1157951000350	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1157951000351	putative active site [active]
1157951000352	putative substrate binding site [chemical binding]; other site
1157951000353	putative cosubstrate binding site; other site
1157951000354	catalytic site [active]
1157951000355	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951000356	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951000357	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1157951000358	putative catalytic site [active]
1157951000359	putative phosphate binding site [ion binding]; other site
1157951000360	active site
1157951000361	metal binding site A [ion binding]; metal-binding site
1157951000362	DNA binding site [nucleotide binding]
1157951000363	putative AP binding site [nucleotide binding]; other site
1157951000364	putative metal binding site B [ion binding]; other site
1157951000365	DNA topoisomerase III; Provisional; Region: PRK07726
1157951000366	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1157951000367	active site
1157951000368	putative interdomain interaction site [polypeptide binding]; other site
1157951000369	putative metal-binding site [ion binding]; other site
1157951000370	putative nucleotide binding site [chemical binding]; other site
1157951000371	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1157951000372	domain I; other site
1157951000373	DNA binding groove [nucleotide binding]
1157951000374	phosphate binding site [ion binding]; other site
1157951000375	domain II; other site
1157951000376	domain III; other site
1157951000377	nucleotide binding site [chemical binding]; other site
1157951000378	catalytic site [active]
1157951000379	domain IV; other site
1157951000380	selenophosphate synthetase; Provisional; Region: PRK00943
1157951000381	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1157951000382	dimerization interface [polypeptide binding]; other site
1157951000383	putative ATP binding site [chemical binding]; other site
1157951000384	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1157951000385	putative FMN binding site [chemical binding]; other site
1157951000386	protease 4; Provisional; Region: PRK10949
1157951000387	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1157951000388	tandem repeat interface [polypeptide binding]; other site
1157951000389	oligomer interface [polypeptide binding]; other site
1157951000390	active site residues [active]
1157951000391	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1157951000392	tandem repeat interface [polypeptide binding]; other site
1157951000393	oligomer interface [polypeptide binding]; other site
1157951000394	active site residues [active]
1157951000395	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1157951000396	active site
1157951000397	homodimer interface [polypeptide binding]; other site
1157951000398	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1157951000399	Isochorismatase family; Region: Isochorismatase; pfam00857
1157951000400	catalytic triad [active]
1157951000401	metal binding site [ion binding]; metal-binding site
1157951000402	conserved cis-peptide bond; other site
1157951000403	Protein of unknown function (DUF1315); Region: DUF1315; pfam07023
1157951000404	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1157951000405	SelR domain; Region: SelR; pfam01641
1157951000406	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1157951000407	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1157951000408	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1157951000409	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1157951000410	active site
1157951000411	phosphate binding residues; other site
1157951000412	catalytic residues [active]
1157951000413	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951000414	Sel1-like repeats; Region: SEL1; smart00671
1157951000415	Sel1-like repeats; Region: SEL1; smart00671
1157951000416	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1157951000417	alanine racemase; Reviewed; Region: dadX; PRK03646
1157951000418	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1157951000419	active site
1157951000420	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1157951000421	substrate binding site [chemical binding]; other site
1157951000422	catalytic residues [active]
1157951000423	dimer interface [polypeptide binding]; other site
1157951000424	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1157951000425	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1157951000426	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1157951000427	fatty acid metabolism regulator; Provisional; Region: PRK04984
1157951000428	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951000429	DNA-binding site [nucleotide binding]; DNA binding site
1157951000430	FadR C-terminal domain; Region: FadR_C; pfam07840
1157951000431	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
1157951000432	disulfide bond formation protein B; Provisional; Region: PRK01749
1157951000433	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1157951000434	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1157951000435	putative arabinose transporter; Provisional; Region: PRK03545
1157951000436	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951000437	putative substrate translocation pore; other site
1157951000438	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1157951000439	putative substrate binding site [chemical binding]; other site
1157951000440	putative ATP binding site [chemical binding]; other site
1157951000441	Protein of unknown function (DUF2594); Region: DUF2594; cl11678
1157951000442	heat shock protein HtpX; Provisional; Region: PRK05457
1157951000443	carboxy-terminal protease; Provisional; Region: PRK11186
1157951000444	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1157951000445	protein binding site [polypeptide binding]; other site
1157951000446	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1157951000447	Catalytic dyad [active]
1157951000448	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1157951000449	ProP expression regulator; Provisional; Region: PRK04950
1157951000450	ProQ/FINO family; Region: ProQ; pfam04352
1157951000451	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1157951000452	GAF domain; Region: GAF_2; pfam13185
1157951000453	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1157951000454	Paraquat-inducible protein A; Region: PqiA; pfam04403
1157951000455	Paraquat-inducible protein A; Region: PqiA; pfam04403
1157951000456	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1157951000457	mce related protein; Region: MCE; pfam02470
1157951000458	mce related protein; Region: MCE; pfam02470
1157951000459	mce related protein; Region: MCE; pfam02470
1157951000460	mce related protein; Region: MCE; pfam02470
1157951000461	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1157951000462	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1157951000463	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1157951000464	Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only]; Region: CopC; COG2372
1157951000465	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1157951000466	Ferritin-like domain; Region: Ferritin; pfam00210
1157951000467	ferroxidase diiron center [ion binding]; other site
1157951000468	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1157951000469	YebF-like protein; Region: YebF; pfam13995
1157951000470	hypothetical protein; Provisional; Region: PRK05114
1157951000471	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1157951000472	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1157951000473	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1157951000474	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1157951000475	putative active site [active]
1157951000476	putative CoA binding site [chemical binding]; other site
1157951000477	nudix motif; other site
1157951000478	metal binding site [ion binding]; metal-binding site
1157951000479	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1157951000480	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1157951000481	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1157951000482	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1157951000483	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1157951000484	active pocket/dimerization site; other site
1157951000485	active site
1157951000486	phosphorylation site [posttranslational modification]
1157951000487	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1157951000488	active site
1157951000489	phosphorylation site [posttranslational modification]
1157951000490	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1157951000491	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1157951000492	hypothetical protein; Provisional; Region: PRK02913
1157951000493	hypothetical protein; Provisional; Region: PRK11469
1157951000494	Domain of unknown function DUF; Region: DUF204; pfam02659
1157951000495	Domain of unknown function DUF; Region: DUF204; pfam02659
1157951000496	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1157951000497	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951000498	S-adenosylmethionine binding site [chemical binding]; other site
1157951000499	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1157951000500	Beta-lactamase; Region: Beta-lactamase; pfam00144
1157951000501	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1157951000502	putative hydrolase; Validated; Region: PRK09248
1157951000503	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1157951000504	active site
1157951000505	alanine racemase; Reviewed; Region: PRK13340
1157951000506	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme, Alanine Racemase 2; Region: PLPDE_III_AR2; cd06826
1157951000507	active site
1157951000508	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1157951000509	dimer interface [polypeptide binding]; other site
1157951000510	substrate binding site [chemical binding]; other site
1157951000511	catalytic residues [active]
1157951000512	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1157951000513	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951000514	oxidoreductase; Provisional; Region: PRK06196
1157951000515	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
1157951000516	putative NAD(P) binding site [chemical binding]; other site
1157951000517	active site
1157951000518	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951000519	non-specific DNA binding site [nucleotide binding]; other site
1157951000520	salt bridge; other site
1157951000521	sequence-specific DNA binding site [nucleotide binding]; other site
1157951000522	HipA N-terminal domain; Region: Couple_hipA; cl11853
1157951000523	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1157951000524	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951000525	DNA-binding site [nucleotide binding]; DNA binding site
1157951000526	UTRA domain; Region: UTRA; pfam07702
1157951000527	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1157951000528	Protein of unknown function (DUF1634); Region: DUF1634; pfam07843
1157951000529	Restriction endonuclease; Region: Mrr_cat; pfam04471
1157951000530	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1157951000531	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1157951000532	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1157951000533	GMP synthase; Reviewed; Region: guaA; PRK00074
1157951000534	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1157951000535	AMP/PPi binding site [chemical binding]; other site
1157951000536	candidate oxyanion hole; other site
1157951000537	catalytic triad [active]
1157951000538	potential glutamine specificity residues [chemical binding]; other site
1157951000539	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1157951000540	ATP Binding subdomain [chemical binding]; other site
1157951000541	Ligand Binding sites [chemical binding]; other site
1157951000542	Dimerization subdomain; other site
1157951000543	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1157951000544	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1157951000545	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1157951000546	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1157951000547	active site
1157951000548	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1157951000549	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1157951000550	generic binding surface II; other site
1157951000551	generic binding surface I; other site
1157951000552	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1157951000553	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1157951000554	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1157951000555	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1157951000556	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1157951000557	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1157951000558	Protein of unknown function, DUF399; Region: DUF399; pfam04187
1157951000559	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1157951000560	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1157951000561	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1157951000562	putative NAD(P) binding site [chemical binding]; other site
1157951000563	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1157951000564	transcriptional regulator NarP; Provisional; Region: PRK10403
1157951000565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951000566	active site
1157951000567	phosphorylation site [posttranslational modification]
1157951000568	intermolecular recognition site; other site
1157951000569	dimerization interface [polypeptide binding]; other site
1157951000570	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1157951000571	DNA binding residues [nucleotide binding]
1157951000572	dimerization interface [polypeptide binding]; other site
1157951000573	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1157951000574	ArsC family; Region: ArsC; pfam03960
1157951000575	putative catalytic residues [active]
1157951000576	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1157951000577	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1157951000578	metal binding site [ion binding]; metal-binding site
1157951000579	dimer interface [polypeptide binding]; other site
1157951000580	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1157951000581	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1157951000582	hypothetical protein; Provisional; Region: PRK10527
1157951000583	Uncharacterized protein family (UPF0370); Region: UPF0370; pfam13980
1157951000584	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1157951000585	Helicase; Region: Helicase_RecD; pfam05127
1157951000586	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1157951000587	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1157951000588	Predicted membrane protein [Function unknown]; Region: COG2707
1157951000589	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
1157951000590	Zn binding site [ion binding]; other site
1157951000591	Predicted metalloprotease [General function prediction only]; Region: COG2321
1157951000592	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1157951000593	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1157951000594	trimer interface [polypeptide binding]; other site
1157951000595	putative Zn binding site [ion binding]; other site
1157951000596	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1157951000597	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1157951000598	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1157951000599	Walker A/P-loop; other site
1157951000600	ATP binding site [chemical binding]; other site
1157951000601	Q-loop/lid; other site
1157951000602	ABC transporter signature motif; other site
1157951000603	Walker B; other site
1157951000604	D-loop; other site
1157951000605	H-loop/switch region; other site
1157951000606	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1157951000607	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1157951000608	Walker A/P-loop; other site
1157951000609	ATP binding site [chemical binding]; other site
1157951000610	Q-loop/lid; other site
1157951000611	ABC transporter signature motif; other site
1157951000612	Walker B; other site
1157951000613	D-loop; other site
1157951000614	H-loop/switch region; other site
1157951000615	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1157951000616	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1157951000617	ATP binding site [chemical binding]; other site
1157951000618	active site
1157951000619	substrate binding site [chemical binding]; other site
1157951000620	lipoprotein; Provisional; Region: PRK11679
1157951000621	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1157951000622	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1157951000623	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1157951000624	dimer interface [polypeptide binding]; other site
1157951000625	active site
1157951000626	catalytic residue [active]
1157951000627	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1157951000628	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1157951000629	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1157951000630	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1157951000631	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1157951000632	catalytic triad [active]
1157951000633	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1157951000634	putative ADP-ribose binding site [chemical binding]; other site
1157951000635	putative active site [active]
1157951000636	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1157951000637	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1157951000638	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1157951000639	Peptidase family M48; Region: Peptidase_M48; pfam01435
1157951000640	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1157951000641	TPR motif; other site
1157951000642	binding surface
1157951000643	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1157951000644	ArsC family; Region: ArsC; pfam03960
1157951000645	catalytic residues [active]
1157951000646	DNA replication initiation factor; Provisional; Region: PRK08084
1157951000647	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1157951000648	uracil transporter; Provisional; Region: PRK10720
1157951000649	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951000650	active site
1157951000651	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1157951000652	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1157951000653	dimerization interface [polypeptide binding]; other site
1157951000654	putative ATP binding site [chemical binding]; other site
1157951000655	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1157951000656	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1157951000657	active site
1157951000658	substrate binding site [chemical binding]; other site
1157951000659	cosubstrate binding site; other site
1157951000660	catalytic site [active]
1157951000661	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1157951000662	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951000663	Coenzyme A binding pocket [chemical binding]; other site
1157951000664	polyphosphate kinase; Provisional; Region: PRK05443
1157951000665	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1157951000666	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1157951000667	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
1157951000668	domain interface [polypeptide binding]; other site
1157951000669	active site
1157951000670	catalytic site [active]
1157951000671	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1157951000672	domain interface [polypeptide binding]; other site
1157951000673	active site
1157951000674	catalytic site [active]
1157951000675	exopolyphosphatase; Provisional; Region: PRK10854
1157951000676	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1157951000677	nucleotide binding site [chemical binding]; other site
1157951000678	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1157951000679	MgtE intracellular N domain; Region: MgtE_N; smart00924
1157951000680	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1157951000681	Divalent cation transporter; Region: MgtE; cl00786
1157951000682	metabolite-proton symporter; Region: 2A0106; TIGR00883
1157951000683	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951000684	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1157951000685	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951000686	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951000687	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1157951000688	Protein export membrane protein; Region: SecD_SecF; cl14618
1157951000689	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1157951000690	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1157951000691	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1157951000692	dimerization interface [polypeptide binding]; other site
1157951000693	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951000694	dimer interface [polypeptide binding]; other site
1157951000695	phosphorylation site [posttranslational modification]
1157951000696	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951000697	ATP binding site [chemical binding]; other site
1157951000698	Mg2+ binding site [ion binding]; other site
1157951000699	G-X-G motif; other site
1157951000700	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1157951000701	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951000702	active site
1157951000703	phosphorylation site [posttranslational modification]
1157951000704	intermolecular recognition site; other site
1157951000705	dimerization interface [polypeptide binding]; other site
1157951000706	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951000707	DNA binding site [nucleotide binding]
1157951000708	putative protease; Provisional; Region: PRK15452
1157951000709	Peptidase family U32; Region: Peptidase_U32; pfam01136
1157951000710	lipid kinase; Reviewed; Region: PRK13054
1157951000711	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1157951000712	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1157951000713	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1157951000714	putative active site; other site
1157951000715	catalytic residue [active]
1157951000716	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1157951000717	dimer interface [polypeptide binding]; other site
1157951000718	substrate binding site [chemical binding]; other site
1157951000719	ATP binding site [chemical binding]; other site
1157951000720	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1157951000721	Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; cl01553
1157951000722	aromatic amino acid transporter; Provisional; Region: PRK10238
1157951000723	MgrB protein; Region: MgrB; pfam13998
1157951000724	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1157951000725	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951000726	sugar phosphate phosphatase; Provisional; Region: PRK10513
1157951000727	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951000728	active site
1157951000729	motif I; other site
1157951000730	motif II; other site
1157951000731	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951000732	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
1157951000733	aromatic amino acid exporter; Provisional; Region: PRK11689
1157951000734	EamA-like transporter family; Region: EamA; pfam00892
1157951000735	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1157951000736	amino acid carrier protein; Region: agcS; TIGR00835
1157951000737	HEAT repeats; Region: HEAT_2; pfam13646
1157951000738	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
1157951000739	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
1157951000740	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
1157951000741	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951000742	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951000743	homodimer interface [polypeptide binding]; other site
1157951000744	catalytic residue [active]
1157951000745	Protein of unknown function, DUF486; Region: DUF486; cl01236
1157951000746	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1157951000747	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951000748	S-adenosylmethionine binding site [chemical binding]; other site
1157951000749	GlpM protein; Region: GlpM; pfam06942
1157951000750	methyl-accepting protein IV; Provisional; Region: PRK09793
1157951000751	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1157951000752	dimer interface [polypeptide binding]; other site
1157951000753	ligand binding site [chemical binding]; other site
1157951000754	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1157951000755	dimer interface [polypeptide binding]; other site
1157951000756	putative CheW interface [polypeptide binding]; other site
1157951000757	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1157951000758	SnoaL-like domain; Region: SnoaL_2; pfam12680
1157951000759	Chloramphenicol acetyltransferase; Region: CAT; pfam00302
1157951000760	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
1157951000761	isocitrate dehydrogenase; Validated; Region: PRK06451
1157951000762	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1157951000763	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1157951000764	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1157951000765	probable active site [active]
1157951000766	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1157951000767	nudix motif; other site
1157951000768	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1157951000769	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1157951000770	putative lysogenization regulator; Reviewed; Region: PRK00218
1157951000771	adenylosuccinate lyase; Provisional; Region: PRK09285
1157951000772	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1157951000773	tetramer interface [polypeptide binding]; other site
1157951000774	active site
1157951000775	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1157951000776	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951000777	active site
1157951000778	phosphorylation site [posttranslational modification]
1157951000779	intermolecular recognition site; other site
1157951000780	dimerization interface [polypeptide binding]; other site
1157951000781	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951000782	DNA binding site [nucleotide binding]
1157951000783	sensor protein PhoQ; Provisional; Region: PRK10815
1157951000784	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1157951000785	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1157951000786	dimer interface [polypeptide binding]; other site
1157951000787	phosphorylation site [posttranslational modification]
1157951000788	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951000789	ATP binding site [chemical binding]; other site
1157951000790	Mg2+ binding site [ion binding]; other site
1157951000791	G-X-G motif; other site
1157951000792	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1157951000793	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1157951000794	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1157951000795	metal binding site [ion binding]; metal-binding site
1157951000796	dimer interface [polypeptide binding]; other site
1157951000797	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1157951000798	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1157951000799	substrate binding pocket [chemical binding]; other site
1157951000800	membrane-bound complex binding site; other site
1157951000801	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1157951000802	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1157951000803	active site
1157951000804	dimer interface [polypeptide binding]; other site
1157951000805	non-prolyl cis peptide bond; other site
1157951000806	insertion regions; other site
1157951000807	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
1157951000808	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1157951000809	Walker A/P-loop; other site
1157951000810	ATP binding site [chemical binding]; other site
1157951000811	Q-loop/lid; other site
1157951000812	ABC transporter signature motif; other site
1157951000813	Walker B; other site
1157951000814	D-loop; other site
1157951000815	H-loop/switch region; other site
1157951000816	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1157951000817	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951000818	dimer interface [polypeptide binding]; other site
1157951000819	conserved gate region; other site
1157951000820	putative PBP binding loops; other site
1157951000821	ABC-ATPase subunit interface; other site
1157951000822	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1157951000823	FMN reductase, SsuE family; Region: FMN_reduc_SsuE; TIGR03567
1157951000824	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1157951000825	classical (c) SDRs; Region: SDR_c; cd05233
1157951000826	NAD(P) binding site [chemical binding]; other site
1157951000827	active site
1157951000828	NAD-dependent deacetylase; Provisional; Region: PRK00481
1157951000829	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1157951000830	NAD+ binding site [chemical binding]; other site
1157951000831	substrate binding site [chemical binding]; other site
1157951000832	Zn binding site [ion binding]; other site
1157951000833	hypothetical protein; Provisional; Region: PRK05208
1157951000834	Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890
1157951000835	putative active site [active]
1157951000836	putative metal binding residues [ion binding]; other site
1157951000837	signature motif; other site
1157951000838	putative triphosphate binding site [ion binding]; other site
1157951000839	dimer interface [polypeptide binding]; other site
1157951000840	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1157951000841	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1157951000842	FtsX-like permease family; Region: FtsX; pfam02687
1157951000843	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1157951000844	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1157951000845	Walker A/P-loop; other site
1157951000846	ATP binding site [chemical binding]; other site
1157951000847	Q-loop/lid; other site
1157951000848	ABC transporter signature motif; other site
1157951000849	Walker B; other site
1157951000850	D-loop; other site
1157951000851	H-loop/switch region; other site
1157951000852	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1157951000853	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1157951000854	FtsX-like permease family; Region: FtsX; pfam02687
1157951000855	transcription-repair coupling factor; Provisional; Region: PRK10689
1157951000856	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1157951000857	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951000858	ATP binding site [chemical binding]; other site
1157951000859	putative Mg++ binding site [ion binding]; other site
1157951000860	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951000861	nucleotide binding region [chemical binding]; other site
1157951000862	ATP-binding site [chemical binding]; other site
1157951000863	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1157951000864	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1157951000865	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1157951000866	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951000867	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
1157951000868	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1157951000869	NAD(P) binding site [chemical binding]; other site
1157951000870	catalytic residues [active]
1157951000871	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1157951000872	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
1157951000873	NAD(P) binding site [chemical binding]; other site
1157951000874	active site
1157951000875	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
1157951000876	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
1157951000877	active site
1157951000878	AmmeMemoRadiSam system radical SAM enzyme; Region: AmmeMemoSam_rS; TIGR04337
1157951000879	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951000880	FeS/SAM binding site; other site
1157951000881	beta-hexosaminidase; Provisional; Region: PRK05337
1157951000882	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1157951000883	thiamine kinase; Region: ycfN_thiK; TIGR02721
1157951000884	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1157951000885	active site
1157951000886	substrate binding site [chemical binding]; other site
1157951000887	ATP binding site [chemical binding]; other site
1157951000888	Protein of unknown function (DUF3897); Region: DUF3897; pfam13036
1157951000889	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1157951000890	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1157951000891	putative dimer interface [polypeptide binding]; other site
1157951000892	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1157951000893	nucleotide binding site/active site [active]
1157951000894	HIT family signature motif; other site
1157951000895	catalytic residue [active]
1157951000896	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1157951000897	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1157951000898	active site
1157951000899	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1157951000900	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1157951000901	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1157951000902	thymidylate kinase; Validated; Region: tmk; PRK00698
1157951000903	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1157951000904	TMP-binding site; other site
1157951000905	ATP-binding site [chemical binding]; other site
1157951000906	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1157951000907	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1157951000908	dimerization interface [polypeptide binding]; other site
1157951000909	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1157951000910	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1157951000911	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951000912	catalytic residue [active]
1157951000913	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1157951000914	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1157951000915	dimer interface [polypeptide binding]; other site
1157951000916	active site
1157951000917	acyl carrier protein; Provisional; Region: acpP; PRK00982
1157951000918	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1157951000919	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1157951000920	NAD(P) binding site [chemical binding]; other site
1157951000921	homotetramer interface [polypeptide binding]; other site
1157951000922	homodimer interface [polypeptide binding]; other site
1157951000923	active site
1157951000924	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1157951000925	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1157951000926	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1157951000927	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1157951000928	dimer interface [polypeptide binding]; other site
1157951000929	active site
1157951000930	CoA binding pocket [chemical binding]; other site
1157951000931	putative phosphate acyltransferase; Provisional; Region: PRK05331
1157951000932	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1157951000933	hypothetical protein; Provisional; Region: PRK11193
1157951000934	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1157951000935	active site
1157951000936	dimer interface [polypeptide binding]; other site
1157951000937	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1157951000938	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1157951000939	RNA binding surface [nucleotide binding]; other site
1157951000940	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1157951000941	active site
1157951000942	ribonuclease E; Reviewed; Region: rne; PRK10811
1157951000943	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1157951000944	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1157951000945	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1157951000946	NAD(P) binding site [chemical binding]; other site
1157951000947	putative active site [active]
1157951000948	hypothetical protein; Provisional; Region: PRK05423
1157951000949	galactoside permease; Reviewed; Region: lacY; PRK09528
1157951000950	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951000951	putative substrate translocation pore; other site
1157951000952	exonuclease I; Provisional; Region: sbcB; PRK11779
1157951000953	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1157951000954	active site
1157951000955	catalytic site [active]
1157951000956	substrate binding site [chemical binding]; other site
1157951000957	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1157951000958	D-lactate dehydrogenase; Provisional; Region: PRK11183
1157951000959	FAD binding domain; Region: FAD_binding_4; pfam01565
1157951000960	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1157951000961	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1157951000962	putative outer membrane receptor; Provisional; Region: PRK13513
1157951000963	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951000964	N-terminal plug; other site
1157951000965	ligand-binding site [chemical binding]; other site
1157951000966	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1157951000967	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1157951000968	Walker A/P-loop; other site
1157951000969	ATP binding site [chemical binding]; other site
1157951000970	Q-loop/lid; other site
1157951000971	ABC transporter signature motif; other site
1157951000972	Walker B; other site
1157951000973	D-loop; other site
1157951000974	H-loop/switch region; other site
1157951000975	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1157951000976	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951000977	ABC-ATPase subunit  interface; other site
1157951000978	dimer interface [polypeptide binding]; other site
1157951000979	putative PBP binding regions; other site
1157951000980	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1157951000981	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
1157951000982	putative ligand binding residues [chemical binding]; other site
1157951000983	lysine transporter; Provisional; Region: PRK10836
1157951000984	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1157951000985	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951000986	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1157951000987	putative dimerization interface [polypeptide binding]; other site
1157951000988	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1157951000989	endonuclease IV; Provisional; Region: PRK01060
1157951000990	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1157951000991	AP (apurinic/apyrimidinic) site pocket; other site
1157951000992	DNA interaction; other site
1157951000993	Metal-binding active site; metal-binding site
1157951000994	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1157951000995	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1157951000996	putative substrate binding site [chemical binding]; other site
1157951000997	putative ATP binding site [chemical binding]; other site
1157951000998	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_19; cd04678
1157951000999	nudix motif; other site
1157951001000	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1157951001001	aromatic amino acid transport protein; Region: araaP; TIGR00837
1157951001002	elongation factor P; Provisional; Region: PRK04542
1157951001003	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1157951001004	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1157951001005	RNA binding site [nucleotide binding]; other site
1157951001006	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1157951001007	RNA binding site [nucleotide binding]; other site
1157951001008	PhoP regulatory network protein YrbL; Region: YrbL-PhoP_reg; cl17608
1157951001009	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1157951001010	NlpC/P60 family; Region: NLPC_P60; pfam00877
1157951001011	YejG-like protein; Region: YejG; cl08201
1157951001012	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1157951001013	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951001014	putative substrate translocation pore; other site
1157951001015	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1157951001016	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1157951001017	RNA binding surface [nucleotide binding]; other site
1157951001018	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1157951001019	active site
1157951001020	uracil binding [chemical binding]; other site
1157951001021	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1157951001022	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951001023	ATP binding site [chemical binding]; other site
1157951001024	putative Mg++ binding site [ion binding]; other site
1157951001025	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951001026	nucleotide binding region [chemical binding]; other site
1157951001027	ATP-binding site [chemical binding]; other site
1157951001028	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1157951001029	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1157951001030	5S rRNA interface [nucleotide binding]; other site
1157951001031	CTC domain interface [polypeptide binding]; other site
1157951001032	L16 interface [polypeptide binding]; other site
1157951001033	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1157951001034	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1157951001035	hypothetical protein; Provisional; Region: PRK13689
1157951001036	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1157951001037	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1157951001038	Sulfatase; Region: Sulfatase; cl17466
1157951001039	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1157951001040	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1157951001041	putative dimer interface [polypeptide binding]; other site
1157951001042	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1157951001043	MASE1; Region: MASE1; cl17823
1157951001044	PAS fold; Region: PAS_3; pfam08447
1157951001045	Protein of unknown function (DUF1345); Region: DUF1345; pfam07077
1157951001046	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1157951001047	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951001048	Coenzyme A binding pocket [chemical binding]; other site
1157951001049	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1157951001050	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951001051	Coenzyme A binding pocket [chemical binding]; other site
1157951001052	DinI-like family; Region: DinI; cl11630
1157951001053	MltA-interacting protein MipA; Region: MipA; cl01504
1157951001054	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1157951001055	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951001056	active site
1157951001057	phosphorylation site [posttranslational modification]
1157951001058	intermolecular recognition site; other site
1157951001059	dimerization interface [polypeptide binding]; other site
1157951001060	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951001061	DNA binding site [nucleotide binding]
1157951001062	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1157951001063	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951001064	dimer interface [polypeptide binding]; other site
1157951001065	phosphorylation site [posttranslational modification]
1157951001066	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951001067	ATP binding site [chemical binding]; other site
1157951001068	Mg2+ binding site [ion binding]; other site
1157951001069	G-X-G motif; other site
1157951001070	Isochorismatase family; Region: Isochorismatase; pfam00857
1157951001071	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1157951001072	catalytic triad [active]
1157951001073	conserved cis-peptide bond; other site
1157951001074	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1157951001075	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1157951001076	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1157951001077	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1157951001078	homodimer interface [polypeptide binding]; other site
1157951001079	substrate-cofactor binding pocket; other site
1157951001080	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951001081	catalytic residue [active]
1157951001082	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
1157951001083	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1157951001084	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1157951001085	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1157951001086	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1157951001087	putative [Fe4-S4] binding site [ion binding]; other site
1157951001088	putative molybdopterin cofactor binding site [chemical binding]; other site
1157951001089	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1157951001090	putative molybdopterin cofactor binding site; other site
1157951001091	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1157951001092	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1157951001093	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1157951001094	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1157951001095	Bacterial protein of unknown function (DUF924); Region: DUF924; pfam06041
1157951001096	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1157951001097	Class II fumarases; Region: Fumarase_classII; cd01362
1157951001098	active site
1157951001099	tetramer interface [polypeptide binding]; other site
1157951001100	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1157951001101	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1157951001102	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1157951001103	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1157951001104	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
1157951001105	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1157951001106	carboxyltransferase (CT) interaction site; other site
1157951001107	biotinylation site [posttranslational modification]; other site
1157951001108	Allophanate hydrolase subunit 1; Region: AHS1; smart00796
1157951001109	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1157951001110	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1157951001111	hypothetical protein; Provisional; Region: PRK05463
1157951001112	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
1157951001113	putative active site [active]
1157951001114	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
1157951001115	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1157951001116	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951001117	DNA-binding site [nucleotide binding]; DNA binding site
1157951001118	FCD domain; Region: FCD; pfam07729
1157951001119	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1157951001120	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1157951001121	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1157951001122	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1157951001123	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1157951001124	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1157951001125	Glycosyl hydrolases family 6; Region: Glyco_hydro_6; pfam01341
1157951001126	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1157951001127	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
1157951001128	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1157951001129	Phage Tail Collar Domain; Region: Collar; pfam07484
1157951001130	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
1157951001131	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1157951001132	Protein of unknown function (DUF2669); Region: DUF2669; pfam10876
1157951001133	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
1157951001134	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
1157951001135	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1157951001136	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1157951001137	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1157951001138	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1157951001139	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1157951001140	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951001141	non-specific DNA binding site [nucleotide binding]; other site
1157951001142	salt bridge; other site
1157951001143	sequence-specific DNA binding site [nucleotide binding]; other site
1157951001144	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1157951001145	Catalytic site [active]
1157951001146	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951001147	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1157951001148	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951001149	ATP binding site [chemical binding]; other site
1157951001150	Mg2+ binding site [ion binding]; other site
1157951001151	G-X-G motif; other site
1157951001152	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1157951001153	putative binding surface; other site
1157951001154	active site
1157951001155	transcriptional regulator RcsB; Provisional; Region: PRK10840
1157951001156	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951001157	active site
1157951001158	phosphorylation site [posttranslational modification]
1157951001159	intermolecular recognition site; other site
1157951001160	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1157951001161	DNA binding residues [nucleotide binding]
1157951001162	dimerization interface [polypeptide binding]; other site
1157951001163	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1157951001164	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951001165	dimer interface [polypeptide binding]; other site
1157951001166	phosphorylation site [posttranslational modification]
1157951001167	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951001168	ATP binding site [chemical binding]; other site
1157951001169	Mg2+ binding site [ion binding]; other site
1157951001170	G-X-G motif; other site
1157951001171	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1157951001172	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951001173	active site
1157951001174	phosphorylation site [posttranslational modification]
1157951001175	intermolecular recognition site; other site
1157951001176	DNA gyrase subunit A; Validated; Region: PRK05560
1157951001177	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1157951001178	CAP-like domain; other site
1157951001179	active site
1157951001180	primary dimer interface [polypeptide binding]; other site
1157951001181	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1157951001182	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1157951001183	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1157951001184	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1157951001185	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1157951001186	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1157951001187	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1157951001188	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951001189	S-adenosylmethionine binding site [chemical binding]; other site
1157951001190	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1157951001191	ATP cone domain; Region: ATP-cone; pfam03477
1157951001192	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1157951001193	active site
1157951001194	dimer interface [polypeptide binding]; other site
1157951001195	catalytic residues [active]
1157951001196	effector binding site; other site
1157951001197	R2 peptide binding site; other site
1157951001198	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1157951001199	dimer interface [polypeptide binding]; other site
1157951001200	putative radical transfer pathway; other site
1157951001201	diiron center [ion binding]; other site
1157951001202	tyrosyl radical; other site
1157951001203	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1157951001204	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1157951001205	catalytic loop [active]
1157951001206	iron binding site [ion binding]; other site
1157951001207	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1157951001208	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1157951001209	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1157951001210	YfaZ precursor; Region: YfaZ; pfam07437
1157951001211	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1157951001212	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1157951001213	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1157951001214	tetramer interface [polypeptide binding]; other site
1157951001215	heme binding pocket [chemical binding]; other site
1157951001216	NADPH binding site [chemical binding]; other site
1157951001217	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1157951001218	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1157951001219	acyl-activating enzyme (AAE) consensus motif; other site
1157951001220	putative AMP binding site [chemical binding]; other site
1157951001221	putative active site [active]
1157951001222	putative CoA binding site [chemical binding]; other site
1157951001223	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1157951001224	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1157951001225	active site
1157951001226	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1157951001227	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1157951001228	substrate binding site [chemical binding]; other site
1157951001229	oxyanion hole (OAH) forming residues; other site
1157951001230	trimer interface [polypeptide binding]; other site
1157951001231	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1157951001232	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1157951001233	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1157951001234	dimer interface [polypeptide binding]; other site
1157951001235	tetramer interface [polypeptide binding]; other site
1157951001236	PYR/PP interface [polypeptide binding]; other site
1157951001237	TPP binding site [chemical binding]; other site
1157951001238	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1157951001239	TPP-binding site; other site
1157951001240	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1157951001241	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1157951001242	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1157951001243	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1157951001244	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1157951001245	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1157951001246	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1157951001247	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1157951001248	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1157951001249	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1157951001250	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1157951001251	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1157951001252	4Fe-4S binding domain; Region: Fer4; pfam00037
1157951001253	4Fe-4S binding domain; Region: Fer4; pfam00037
1157951001254	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1157951001255	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1157951001256	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1157951001257	catalytic loop [active]
1157951001258	iron binding site [ion binding]; other site
1157951001259	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1157951001260	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1157951001261	[4Fe-4S] binding site [ion binding]; other site
1157951001262	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1157951001263	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1157951001264	SLBB domain; Region: SLBB; pfam10531
1157951001265	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1157951001266	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1157951001267	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1157951001268	putative dimer interface [polypeptide binding]; other site
1157951001269	[2Fe-2S] cluster binding site [ion binding]; other site
1157951001270	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1157951001271	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1157951001272	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1157951001273	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1157951001274	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1157951001275	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1157951001276	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951001277	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1157951001278	putative dimerization interface [polypeptide binding]; other site
1157951001279	aminotransferase AlaT; Validated; Region: PRK09265
1157951001280	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951001281	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951001282	homodimer interface [polypeptide binding]; other site
1157951001283	catalytic residue [active]
1157951001284	5'-nucleotidase; Provisional; Region: PRK03826
1157951001285	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1157951001286	transmembrane helices; other site
1157951001287	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1157951001288	TrkA-C domain; Region: TrkA_C; pfam02080
1157951001289	TrkA-C domain; Region: TrkA_C; pfam02080
1157951001290	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1157951001291	putative phosphatase; Provisional; Region: PRK11587
1157951001292	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951001293	motif II; other site
1157951001294	hypothetical protein; Validated; Region: PRK05445
1157951001295	hypothetical protein; Provisional; Region: PRK01816
1157951001296	propionate/acetate kinase; Provisional; Region: PRK12379
1157951001297	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1157951001298	phosphate acetyltransferase; Reviewed; Region: PRK05632
1157951001299	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1157951001300	DRTGG domain; Region: DRTGG; pfam07085
1157951001301	phosphate acetyltransferase; Region: pta; TIGR00651
1157951001302	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1157951001303	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1157951001304	Na binding site [ion binding]; other site
1157951001305	Protein of unknown function (DUF3311); Region: DUF3311; pfam11755
1157951001306	putative endopeptidase; Provisional; Region: PRK14576
1157951001307	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1157951001308	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1157951001309	active site
1157951001310	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1157951001311	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1157951001312	nudix motif; other site
1157951001313	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1157951001314	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1157951001315	putative NAD(P) binding site [chemical binding]; other site
1157951001316	putative active site [active]
1157951001317	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1157951001318	Flavoprotein; Region: Flavoprotein; pfam02441
1157951001319	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3878
1157951001320	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1157951001321	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1157951001322	active site
1157951001323	tetramer interface [polypeptide binding]; other site
1157951001324	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951001325	active site
1157951001326	Colicin V production protein; Region: Colicin_V; cl00567
1157951001327	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1157951001328	Sporulation related domain; Region: SPOR; pfam05036
1157951001329	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1157951001330	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1157951001331	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1157951001332	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1157951001333	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1157951001334	hypothetical protein; Provisional; Region: PRK10847
1157951001335	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1157951001336	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1157951001337	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1157951001338	dimerization interface 3.5A [polypeptide binding]; other site
1157951001339	active site
1157951001340	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1157951001341	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1157951001342	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1157951001343	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1157951001344	ligand binding site [chemical binding]; other site
1157951001345	NAD binding site [chemical binding]; other site
1157951001346	catalytic site [active]
1157951001347	homodimer interface [polypeptide binding]; other site
1157951001348	Cupin domain; Region: Cupin_2; cl17218
1157951001349	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951001350	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1157951001351	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951001352	EamA-like transporter family; Region: EamA; pfam00892
1157951001353	EamA-like transporter family; Region: EamA; pfam00892
1157951001354	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951001355	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1157951001356	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951001357	dimer interface [polypeptide binding]; other site
1157951001358	phosphorylation site [posttranslational modification]
1157951001359	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951001360	ATP binding site [chemical binding]; other site
1157951001361	Mg2+ binding site [ion binding]; other site
1157951001362	G-X-G motif; other site
1157951001363	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
1157951001364	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951001365	active site
1157951001366	phosphorylation site [posttranslational modification]
1157951001367	intermolecular recognition site; other site
1157951001368	dimerization interface [polypeptide binding]; other site
1157951001369	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951001370	DNA binding site [nucleotide binding]
1157951001371	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1157951001372	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1157951001373	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1157951001374	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1157951001375	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1157951001376	dimer interface [polypeptide binding]; other site
1157951001377	active site
1157951001378	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1157951001379	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1157951001380	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1157951001381	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1157951001382	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951001383	Coenzyme A binding pocket [chemical binding]; other site
1157951001384	YfcL protein; Region: YfcL; pfam08891
1157951001385	Protein of unknown function, DUF462; Region: DUF462; pfam04315
1157951001386	hypothetical protein; Provisional; Region: PRK10621
1157951001387	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1157951001388	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1157951001389	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1157951001390	Tetramer interface [polypeptide binding]; other site
1157951001391	active site
1157951001392	FMN-binding site [chemical binding]; other site
1157951001393	HemK family putative methylases; Region: hemK_fam; TIGR00536
1157951001394	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951001395	S-adenosylmethionine binding site [chemical binding]; other site
1157951001396	putative proline-specific permease; Provisional; Region: proY; PRK10580
1157951001397	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1157951001398	active sites [active]
1157951001399	tetramer interface [polypeptide binding]; other site
1157951001400	urocanate hydratase; Provisional; Region: PRK05414
1157951001401	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
1157951001402	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951001403	DNA-binding site [nucleotide binding]; DNA binding site
1157951001404	UTRA domain; Region: UTRA; pfam07702
1157951001405	imidazolonepropionase; Validated; Region: PRK09356
1157951001406	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1157951001407	active site
1157951001408	hypothetical protein; Provisional; Region: PRK04946
1157951001409	Smr domain; Region: Smr; pfam01713
1157951001410	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1157951001411	catalytic core [active]
1157951001412	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1157951001413	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1157951001414	substrate binding site [chemical binding]; other site
1157951001415	oxyanion hole (OAH) forming residues; other site
1157951001416	trimer interface [polypeptide binding]; other site
1157951001417	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1157951001418	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1157951001419	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1157951001420	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1157951001421	dimer interface [polypeptide binding]; other site
1157951001422	active site
1157951001423	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1157951001424	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1157951001425	VacJ like lipoprotein; Region: VacJ; cl01073
1157951001426	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
1157951001427	protein binding surface [polypeptide binding]; other site
1157951001428	HEAT-like repeat; Region: HEAT_EZ; pfam13513
1157951001429	Bacterial protein of unknown function (DUF898); Region: DUF898; pfam05987
1157951001430	Peptidase family M48; Region: Peptidase_M48; cl12018
1157951001431	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1157951001432	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1157951001433	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1157951001434	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1157951001435	transmembrane helices; other site
1157951001436	Molybdenum cofactor biosynthesis protein F; Region: MoaF; pfam10703
1157951001437	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1157951001438	classical (c) SDRs; Region: SDR_c; cd05233
1157951001439	NAD(P) binding site [chemical binding]; other site
1157951001440	active site
1157951001441	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1157951001442	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1157951001443	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1157951001444	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950; cl17731
1157951001445	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1157951001446	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
1157951001447	Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072
1157951001448	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
1157951001449	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1157951001450	Walker A/P-loop; other site
1157951001451	ATP binding site [chemical binding]; other site
1157951001452	ABC transporter; Region: ABC_tran; pfam00005
1157951001453	Q-loop/lid; other site
1157951001454	ABC transporter signature motif; other site
1157951001455	Walker B; other site
1157951001456	D-loop; other site
1157951001457	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951001458	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1157951001459	NIL domain; Region: NIL; pfam09383
1157951001460	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951001461	dimer interface [polypeptide binding]; other site
1157951001462	conserved gate region; other site
1157951001463	ABC-ATPase subunit interface; other site
1157951001464	potassium/proton antiporter; Reviewed; Region: PRK05326
1157951001465	TrkA-C domain; Region: TrkA_C; pfam02080
1157951001466	Transporter associated domain; Region: CorC_HlyC; smart01091
1157951001467	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951001468	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951001469	non-specific DNA binding site [nucleotide binding]; other site
1157951001470	salt bridge; other site
1157951001471	sequence-specific DNA binding site [nucleotide binding]; other site
1157951001472	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1157951001473	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1157951001474	HIGH motif; other site
1157951001475	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1157951001476	active site
1157951001477	KMSKS motif; other site
1157951001478	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1157951001479	classical (c) SDRs; Region: SDR_c; cd05233
1157951001480	NAD(P) binding site [chemical binding]; other site
1157951001481	active site
1157951001482	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1157951001483	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1157951001484	putative DNA binding site [nucleotide binding]; other site
1157951001485	putative Zn2+ binding site [ion binding]; other site
1157951001486	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
1157951001487	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1157951001488	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1157951001489	Nucleoside recognition; Region: Gate; pfam07670
1157951001490	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1157951001491	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1157951001492	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1157951001493	nucleotide binding pocket [chemical binding]; other site
1157951001494	K-X-D-G motif; other site
1157951001495	catalytic site [active]
1157951001496	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1157951001497	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1157951001498	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
1157951001499	DNA binding site [nucleotide binding]
1157951001500	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1157951001501	Dimer interface [polypeptide binding]; other site
1157951001502	BRCT sequence motif; other site
1157951001503	cell division protein ZipA; Provisional; Region: PRK03427
1157951001504	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1157951001505	FtsZ protein binding site [polypeptide binding]; other site
1157951001506	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1157951001507	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1157951001508	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1157951001509	dimer interface [polypeptide binding]; other site
1157951001510	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951001511	catalytic residue [active]
1157951001512	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1157951001513	dimerization domain swap beta strand [polypeptide binding]; other site
1157951001514	regulatory protein interface [polypeptide binding]; other site
1157951001515	active site
1157951001516	regulatory phosphorylation site [posttranslational modification]; other site
1157951001517	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1157951001518	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1157951001519	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1157951001520	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1157951001521	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1157951001522	HPr interaction site; other site
1157951001523	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1157951001524	active site
1157951001525	phosphorylation site [posttranslational modification]
1157951001526	cysteine synthase B; Region: cysM; TIGR01138
1157951001527	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1157951001528	dimer interface [polypeptide binding]; other site
1157951001529	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951001530	catalytic residue [active]
1157951001531	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1157951001532	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1157951001533	Walker A/P-loop; other site
1157951001534	ATP binding site [chemical binding]; other site
1157951001535	Q-loop/lid; other site
1157951001536	ABC transporter signature motif; other site
1157951001537	Walker B; other site
1157951001538	D-loop; other site
1157951001539	H-loop/switch region; other site
1157951001540	sulfate transport protein; Provisional; Region: cysT; CHL00187
1157951001541	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951001542	dimer interface [polypeptide binding]; other site
1157951001543	conserved gate region; other site
1157951001544	putative PBP binding loops; other site
1157951001545	ABC-ATPase subunit interface; other site
1157951001546	sulfate transport protein; Provisional; Region: cysT; CHL00187
1157951001547	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951001548	dimer interface [polypeptide binding]; other site
1157951001549	conserved gate region; other site
1157951001550	putative PBP binding loops; other site
1157951001551	ABC-ATPase subunit interface; other site
1157951001552	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1157951001553	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1157951001554	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1157951001555	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1157951001556	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1157951001557	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1157951001558	putative acetyltransferase; Provisional; Region: PRK03624
1157951001559	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951001560	Coenzyme A binding pocket [chemical binding]; other site
1157951001561	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1157951001562	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1157951001563	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1157951001564	active site
1157951001565	Zn binding site [ion binding]; other site
1157951001566	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1157951001567	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1157951001568	RNA binding surface [nucleotide binding]; other site
1157951001569	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1157951001570	probable active site [active]
1157951001571	GTP-binding protein Der; Reviewed; Region: PRK00093
1157951001572	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1157951001573	G1 box; other site
1157951001574	GTP/Mg2+ binding site [chemical binding]; other site
1157951001575	Switch I region; other site
1157951001576	G2 box; other site
1157951001577	Switch II region; other site
1157951001578	G3 box; other site
1157951001579	G4 box; other site
1157951001580	G5 box; other site
1157951001581	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1157951001582	G1 box; other site
1157951001583	GTP/Mg2+ binding site [chemical binding]; other site
1157951001584	Switch I region; other site
1157951001585	G2 box; other site
1157951001586	G3 box; other site
1157951001587	Switch II region; other site
1157951001588	G4 box; other site
1157951001589	G5 box; other site
1157951001590	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1157951001591	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1157951001592	Trp docking motif [polypeptide binding]; other site
1157951001593	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1157951001594	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1157951001595	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1157951001596	dimer interface [polypeptide binding]; other site
1157951001597	motif 1; other site
1157951001598	active site
1157951001599	motif 2; other site
1157951001600	motif 3; other site
1157951001601	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1157951001602	anticodon binding site; other site
1157951001603	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1157951001604	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1157951001605	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1157951001606	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951001607	non-specific DNA binding site [nucleotide binding]; other site
1157951001608	salt bridge; other site
1157951001609	sequence-specific DNA binding site [nucleotide binding]; other site
1157951001610	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1157951001611	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1157951001612	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1157951001613	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951001614	FeS/SAM binding site; other site
1157951001615	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1157951001616	active site
1157951001617	multimer interface [polypeptide binding]; other site
1157951001618	penicillin-binding protein 1C; Provisional; Region: PRK11240
1157951001619	Transglycosylase; Region: Transgly; pfam00912
1157951001620	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1157951001621	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1157951001622	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1157951001623	MG2 domain; Region: A2M_N; pfam01835
1157951001624	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1157951001625	surface patch; other site
1157951001626	thioester region; other site
1157951001627	specificity defining residues; other site
1157951001628	putative transposase; Provisional; Region: PRK09857
1157951001629	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1157951001630	SseB protein; Region: SseB; cl06279
1157951001631	aminopeptidase B; Provisional; Region: PRK05015
1157951001632	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1157951001633	interface (dimer of trimers) [polypeptide binding]; other site
1157951001634	Substrate-binding/catalytic site; other site
1157951001635	Zn-binding sites [ion binding]; other site
1157951001636	hypothetical protein; Provisional; Region: PRK10721
1157951001637	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1157951001638	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1157951001639	catalytic loop [active]
1157951001640	iron binding site [ion binding]; other site
1157951001641	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1157951001642	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1157951001643	nucleotide binding site [chemical binding]; other site
1157951001644	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1157951001645	SBD interface [polypeptide binding]; other site
1157951001646	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1157951001647	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1157951001648	HSP70 interaction site [polypeptide binding]; other site
1157951001649	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1157951001650	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1157951001651	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1157951001652	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1157951001653	trimerization site [polypeptide binding]; other site
1157951001654	active site
1157951001655	cysteine desulfurase; Provisional; Region: PRK14012
1157951001656	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1157951001657	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951001658	catalytic residue [active]
1157951001659	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1157951001660	Rrf2 family protein; Region: rrf2_super; TIGR00738
1157951001661	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1157951001662	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1157951001663	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1157951001664	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1157951001665	active site
1157951001666	dimerization interface [polypeptide binding]; other site
1157951001667	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1157951001668	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1157951001669	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1157951001670	dimer interface [polypeptide binding]; other site
1157951001671	active site
1157951001672	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1157951001673	folate binding site [chemical binding]; other site
1157951001674	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1157951001675	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1157951001676	heme-binding site [chemical binding]; other site
1157951001677	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1157951001678	FAD binding pocket [chemical binding]; other site
1157951001679	FAD binding motif [chemical binding]; other site
1157951001680	phosphate binding motif [ion binding]; other site
1157951001681	beta-alpha-beta structure motif; other site
1157951001682	NAD binding pocket [chemical binding]; other site
1157951001683	Heme binding  pocket [chemical binding]; other site
1157951001684	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1157951001685	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1157951001686	NAD synthetase; Provisional; Region: PRK13981
1157951001687	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
1157951001688	multimer interface [polypeptide binding]; other site
1157951001689	active site
1157951001690	catalytic triad [active]
1157951001691	protein interface 1 [polypeptide binding]; other site
1157951001692	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1157951001693	homodimer interface [polypeptide binding]; other site
1157951001694	NAD binding pocket [chemical binding]; other site
1157951001695	ATP binding pocket [chemical binding]; other site
1157951001696	Mg binding site [ion binding]; other site
1157951001697	active-site loop [active]
1157951001698	response regulator GlrR; Provisional; Region: PRK15115
1157951001699	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951001700	active site
1157951001701	phosphorylation site [posttranslational modification]
1157951001702	intermolecular recognition site; other site
1157951001703	dimerization interface [polypeptide binding]; other site
1157951001704	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951001705	Walker A motif; other site
1157951001706	ATP binding site [chemical binding]; other site
1157951001707	Walker B motif; other site
1157951001708	arginine finger; other site
1157951001709	YfhG lipoprotein; Region: Lipoprotein_20; pfam13942
1157951001710	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1157951001711	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951001712	dimer interface [polypeptide binding]; other site
1157951001713	phosphorylation site [posttranslational modification]
1157951001714	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951001715	ATP binding site [chemical binding]; other site
1157951001716	Mg2+ binding site [ion binding]; other site
1157951001717	G-X-G motif; other site
1157951001718	O-methyltransferase; Region: Methyltransf_2; pfam00891
1157951001719	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1157951001720	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1157951001721	dimerization interface [polypeptide binding]; other site
1157951001722	ATP binding site [chemical binding]; other site
1157951001723	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1157951001724	dimerization interface [polypeptide binding]; other site
1157951001725	ATP binding site [chemical binding]; other site
1157951001726	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1157951001727	putative active site [active]
1157951001728	catalytic triad [active]
1157951001729	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1157951001730	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1157951001731	substrate binding pocket [chemical binding]; other site
1157951001732	membrane-bound complex binding site; other site
1157951001733	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1157951001734	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1157951001735	catalytic residue [active]
1157951001736	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1157951001737	nucleoside/Zn binding site; other site
1157951001738	dimer interface [polypeptide binding]; other site
1157951001739	catalytic motif [active]
1157951001740	leucine export protein LeuE; Provisional; Region: PRK10958
1157951001741	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1157951001742	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1157951001743	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1157951001744	active site
1157951001745	hydrophilic channel; other site
1157951001746	dimerization interface [polypeptide binding]; other site
1157951001747	catalytic residues [active]
1157951001748	active site lid [active]
1157951001749	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1157951001750	Recombination protein O N terminal; Region: RecO_N; pfam11967
1157951001751	Recombination protein O C terminal; Region: RecO_C; pfam02565
1157951001752	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1157951001753	GTPase Era; Reviewed; Region: era; PRK00089
1157951001754	G1 box; other site
1157951001755	GTP/Mg2+ binding site [chemical binding]; other site
1157951001756	Switch I region; other site
1157951001757	G2 box; other site
1157951001758	Switch II region; other site
1157951001759	G3 box; other site
1157951001760	G4 box; other site
1157951001761	G5 box; other site
1157951001762	KH domain; Region: KH_2; pfam07650
1157951001763	ribonuclease III; Reviewed; Region: rnc; PRK00102
1157951001764	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1157951001765	dimerization interface [polypeptide binding]; other site
1157951001766	active site
1157951001767	metal binding site [ion binding]; metal-binding site
1157951001768	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1157951001769	dsRNA binding site [nucleotide binding]; other site
1157951001770	signal peptidase I; Provisional; Region: PRK10861
1157951001771	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1157951001772	Catalytic site [active]
1157951001773	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1157951001774	GTP-binding protein LepA; Provisional; Region: PRK05433
1157951001775	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1157951001776	G1 box; other site
1157951001777	putative GEF interaction site [polypeptide binding]; other site
1157951001778	GTP/Mg2+ binding site [chemical binding]; other site
1157951001779	Switch I region; other site
1157951001780	G2 box; other site
1157951001781	G3 box; other site
1157951001782	Switch II region; other site
1157951001783	G4 box; other site
1157951001784	G5 box; other site
1157951001785	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1157951001786	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1157951001787	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1157951001788	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; cl01178
1157951001789	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1157951001790	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1157951001791	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1157951001792	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1157951001793	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1157951001794	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1157951001795	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1157951001796	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1157951001797	DNA binding residues [nucleotide binding]
1157951001798	L-aspartate oxidase; Provisional; Region: PRK09077
1157951001799	L-aspartate oxidase; Provisional; Region: PRK06175
1157951001800	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1157951001801	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1157951001802	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951001803	S-adenosylmethionine binding site [chemical binding]; other site
1157951001804	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1157951001805	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1157951001806	Bacterial transcriptional regulator; Region: IclR; pfam01614
1157951001807	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1157951001808	putative active site [active]
1157951001809	putative metal binding site [ion binding]; other site
1157951001810	Sodium/glutamate symporter; Region: Glt_symporter; pfam03616
1157951001811	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1157951001812	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1157951001813	ATP binding site [chemical binding]; other site
1157951001814	Mg++ binding site [ion binding]; other site
1157951001815	motif III; other site
1157951001816	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951001817	nucleotide binding region [chemical binding]; other site
1157951001818	ATP-binding site [chemical binding]; other site
1157951001819	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1157951001820	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1157951001821	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1157951001822	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1157951001823	ligand binding site [chemical binding]; other site
1157951001824	active site
1157951001825	UGI interface [polypeptide binding]; other site
1157951001826	catalytic site [active]
1157951001827	GrpE; Region: GrpE; pfam01025
1157951001828	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1157951001829	dimer interface [polypeptide binding]; other site
1157951001830	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1157951001831	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1157951001832	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1157951001833	recombination and repair protein; Provisional; Region: PRK10869
1157951001834	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1157951001835	Walker A/P-loop; other site
1157951001836	ATP binding site [chemical binding]; other site
1157951001837	Q-loop/lid; other site
1157951001838	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1157951001839	ABC transporter signature motif; other site
1157951001840	Walker B; other site
1157951001841	D-loop; other site
1157951001842	H-loop/switch region; other site
1157951001843	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1157951001844	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1157951001845	RnfH family Ubiquitin; Region: Ub-RnfH; cl17382
1157951001846	RnfH family Ubiquitin; Region: Ub-RnfH; cl17382
1157951001847	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1157951001848	putative coenzyme Q binding site [chemical binding]; other site
1157951001849	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1157951001850	SmpB-tmRNA interface; other site
1157951001851	integrase; Provisional; Region: PRK09692
1157951001852	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1157951001853	active site
1157951001854	Int/Topo IB signature motif; other site
1157951001855	Caspase domain; Region: Peptidase_C14; pfam00656
1157951001856	substrate pocket [chemical binding]; other site
1157951001857	active site
1157951001858	proteolytic cleavage site; other site
1157951001859	dimer interface [polypeptide binding]; other site
1157951001860	Domain of unknown function (DUF927); Region: DUF927; pfam06048
1157951001861	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1157951001862	Ash protein family; Region: Phage_ASH; pfam10554
1157951001863	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951001864	non-specific DNA binding site [nucleotide binding]; other site
1157951001865	salt bridge; other site
1157951001866	sequence-specific DNA binding site [nucleotide binding]; other site
1157951001867	Domain of unknown function (DUF955); Region: DUF955; cl01076
1157951001868	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1157951001869	Transposase; Region: HTH_Tnp_1; cl17663
1157951001870	Transposase; Region: HTH_Tnp_1; cl17663
1157951001871	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1157951001872	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1157951001873	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951001874	Coenzyme A binding pocket [chemical binding]; other site
1157951001875	Low-density lipoprotein-receptor YWTD domain; Region: LY; smart00135
1157951001876	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1157951001877	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951001878	putative MFS family transporter protein; Provisional; Region: PRK03633
1157951001879	putative substrate translocation pore; other site
1157951001880	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1157951001881	Propionate catabolism activator; Region: PrpR_N; pfam06506
1157951001882	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951001883	Walker A motif; other site
1157951001884	ATP binding site [chemical binding]; other site
1157951001885	Walker B motif; other site
1157951001886	arginine finger; other site
1157951001887	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1157951001888	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1157951001889	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1157951001890	tetramer interface [polypeptide binding]; other site
1157951001891	active site
1157951001892	Mg2+/Mn2+ binding site [ion binding]; other site
1157951001893	methylcitrate synthase; Provisional; Region: PRK12351
1157951001894	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1157951001895	oxalacetate binding site [chemical binding]; other site
1157951001896	citrylCoA binding site [chemical binding]; other site
1157951001897	coenzyme A binding site [chemical binding]; other site
1157951001898	catalytic triad [active]
1157951001899	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1157951001900	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1157951001901	benzoylformate decarboxylase; Reviewed; Region: PRK07092
1157951001902	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1157951001903	PYR/PP interface [polypeptide binding]; other site
1157951001904	dimer interface [polypeptide binding]; other site
1157951001905	TPP binding site [chemical binding]; other site
1157951001906	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951001907	Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of...; Region: TPP_BFDC; cd02002
1157951001908	TPP-binding site [chemical binding]; other site
1157951001909	dimer interface [polypeptide binding]; other site
1157951001910	Membrane transport protein; Region: Mem_trans; cl09117
1157951001911	Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) and related proteins; solute binding domain; Region: SLC5sbd_vSGLT; cd10325
1157951001912	putative transporter; Provisional; Region: PRK10484
1157951001913	Na binding site [ion binding]; other site
1157951001914	substrate binding site [chemical binding]; other site
1157951001915	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1157951001916	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951001917	DNA binding site [nucleotide binding]
1157951001918	domain linker motif; other site
1157951001919	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1157951001920	dimerization interface (closed form) [polypeptide binding]; other site
1157951001921	ligand binding site [chemical binding]; other site
1157951001922	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1157951001923	active site
1157951001924	catalytic residues [active]
1157951001925	galactokinase; Provisional; Region: PRK05101
1157951001926	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1157951001927	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1157951001928	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1157951001929	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1157951001930	dimer interface [polypeptide binding]; other site
1157951001931	active site
1157951001932	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1157951001933	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1157951001934	NAD binding site [chemical binding]; other site
1157951001935	homodimer interface [polypeptide binding]; other site
1157951001936	active site
1157951001937	substrate binding site [chemical binding]; other site
1157951001938	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1157951001939	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1157951001940	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1157951001941	Ligand Binding Site [chemical binding]; other site
1157951001942	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cl00178
1157951001943	secondary substrate binding site; other site
1157951001944	primary substrate binding site; other site
1157951001945	inhibition loop; other site
1157951001946	dimerization interface [polypeptide binding]; other site
1157951001947	Protein of unknown function (DUF465); Region: DUF465; cl01070
1157951001948	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1157951001949	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1157951001950	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951001951	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1157951001952	hypothetical protein; Provisional; Region: PRK11281
1157951001953	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1157951001954	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1157951001955	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1157951001956	dimer interface [polypeptide binding]; other site
1157951001957	putative anticodon binding site; other site
1157951001958	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1157951001959	motif 1; other site
1157951001960	active site
1157951001961	motif 2; other site
1157951001962	motif 3; other site
1157951001963	peptide chain release factor 2; Provisional; Region: PRK08787
1157951001964	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1157951001965	RF-1 domain; Region: RF-1; pfam00472
1157951001966	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1157951001967	DHH family; Region: DHH; pfam01368
1157951001968	DHHA1 domain; Region: DHHA1; pfam02272
1157951001969	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1157951001970	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1157951001971	dimerization domain [polypeptide binding]; other site
1157951001972	dimer interface [polypeptide binding]; other site
1157951001973	catalytic residues [active]
1157951001974	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1157951001975	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1157951001976	active site
1157951001977	Int/Topo IB signature motif; other site
1157951001978	flavodoxin FldB; Provisional; Region: PRK12359
1157951001979	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1157951001980	hypothetical protein; Provisional; Region: PRK10878
1157951001981	putative global regulator; Reviewed; Region: PRK09559
1157951001982	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1157951001983	HD domain; Region: HD_3; pfam13023
1157951001984	glycine dehydrogenase; Provisional; Region: PRK05367
1157951001985	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1157951001986	tetramer interface [polypeptide binding]; other site
1157951001987	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951001988	catalytic residue [active]
1157951001989	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1157951001990	tetramer interface [polypeptide binding]; other site
1157951001991	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951001992	catalytic residue [active]
1157951001993	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1157951001994	lipoyl attachment site [posttranslational modification]; other site
1157951001995	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1157951001996	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1157951001997	oxidoreductase; Provisional; Region: PRK08013
1157951001998	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1157951001999	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1157951002000	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
1157951002001	proline aminopeptidase P II; Provisional; Region: PRK10879
1157951002002	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1157951002003	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1157951002004	active site
1157951002005	hypothetical protein; Reviewed; Region: PRK01736
1157951002006	Z-ring-associated protein; Provisional; Region: PRK10972
1157951002007	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1157951002008	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
1157951002009	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1157951002010	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1157951002011	ligand binding site [chemical binding]; other site
1157951002012	NAD binding site [chemical binding]; other site
1157951002013	tetramer interface [polypeptide binding]; other site
1157951002014	catalytic site [active]
1157951002015	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1157951002016	L-serine binding site [chemical binding]; other site
1157951002017	ACT domain interface; other site
1157951002018	YcxB-like protein; Region: YcxB; pfam14317
1157951002019	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1157951002020	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1157951002021	active site
1157951002022	dimer interface [polypeptide binding]; other site
1157951002023	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1157951002024	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951002025	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1157951002026	putative dimerization interface [polypeptide binding]; other site
1157951002027	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1157951002028	oxidative stress defense protein; Provisional; Region: PRK11087
1157951002029	arginine exporter protein; Provisional; Region: PRK09304
1157951002030	mechanosensitive channel MscS; Provisional; Region: PRK10334
1157951002031	Conserved TM helix; Region: TM_helix; pfam05552
1157951002032	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1157951002033	hypothetical protein; Provisional; Region: PRK05248
1157951002034	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
1157951002035	dimer interface [polypeptide binding]; other site
1157951002036	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1157951002037	metal binding site [ion binding]; metal-binding site
1157951002038	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1157951002039	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1157951002040	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1157951002041	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1157951002042	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951002043	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951002044	non-specific DNA binding site [nucleotide binding]; other site
1157951002045	salt bridge; other site
1157951002046	sequence-specific DNA binding site [nucleotide binding]; other site
1157951002047	putative fimbrial chaperone protein; Provisional; Region: PRK09918
1157951002048	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951002049	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
1157951002050	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951002051	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951002052	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1157951002053	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1157951002054	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1157951002055	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1157951002056	substrate binding site [chemical binding]; other site
1157951002057	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1157951002058	substrate binding site [chemical binding]; other site
1157951002059	ligand binding site [chemical binding]; other site
1157951002060	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1157951002061	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1157951002062	active site
1157951002063	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1157951002064	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1157951002065	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951002066	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1157951002067	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1157951002068	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1157951002069	E3 interaction surface; other site
1157951002070	lipoyl attachment site [posttranslational modification]; other site
1157951002071	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1157951002072	E3 interaction surface; other site
1157951002073	lipoyl attachment site [posttranslational modification]; other site
1157951002074	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1157951002075	E3 interaction surface; other site
1157951002076	lipoyl attachment site [posttranslational modification]; other site
1157951002077	e3 binding domain; Region: E3_binding; pfam02817
1157951002078	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1157951002079	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1157951002080	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1157951002081	dimer interface [polypeptide binding]; other site
1157951002082	TPP-binding site [chemical binding]; other site
1157951002083	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1157951002084	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951002085	DNA-binding site [nucleotide binding]; DNA binding site
1157951002086	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1157951002087	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1157951002088	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1157951002089	dimerization interface [polypeptide binding]; other site
1157951002090	active site
1157951002091	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cl02712
1157951002092	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1157951002093	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1157951002094	amidase catalytic site [active]
1157951002095	substrate binding site [chemical binding]; other site
1157951002096	Zn binding residues [ion binding]; other site
1157951002097	putative major pilin subunit; Provisional; Region: PRK10574
1157951002098	hypothetical protein; Provisional; Region: PRK10436
1157951002099	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1157951002100	Walker A motif; other site
1157951002101	ATP binding site [chemical binding]; other site
1157951002102	Walker B motif; other site
1157951002103	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1157951002104	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1157951002105	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1157951002106	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1157951002107	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1157951002108	CoA-binding site [chemical binding]; other site
1157951002109	ATP-binding [chemical binding]; other site
1157951002110	hypothetical protein; Provisional; Region: PRK05287
1157951002111	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1157951002112	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1157951002113	active site
1157951002114	8-oxo-dGMP binding site [chemical binding]; other site
1157951002115	nudix motif; other site
1157951002116	metal binding site [ion binding]; metal-binding site
1157951002117	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1157951002118	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1157951002119	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1157951002120	nucleotide binding region [chemical binding]; other site
1157951002121	ATP-binding site [chemical binding]; other site
1157951002122	SEC-C motif; Region: SEC-C; pfam02810
1157951002123	SecA regulator SecM; Provisional; Region: PRK02943
1157951002124	Protein of unknown function (DUF721); Region: DUF721; cl02324
1157951002125	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1157951002126	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1157951002127	cell division protein FtsZ; Validated; Region: PRK09330
1157951002128	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1157951002129	nucleotide binding site [chemical binding]; other site
1157951002130	SulA interaction site; other site
1157951002131	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1157951002132	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1157951002133	Cell division protein FtsA; Region: FtsA; pfam14450
1157951002134	cell division protein FtsQ; Provisional; Region: PRK10775
1157951002135	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1157951002136	Cell division protein FtsQ; Region: FtsQ; pfam03799
1157951002137	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1157951002138	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1157951002139	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1157951002140	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1157951002141	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1157951002142	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1157951002143	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1157951002144	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1157951002145	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1157951002146	active site
1157951002147	homodimer interface [polypeptide binding]; other site
1157951002148	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1157951002149	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1157951002150	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1157951002151	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1157951002152	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1157951002153	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1157951002154	Mg++ binding site [ion binding]; other site
1157951002155	putative catalytic motif [active]
1157951002156	putative substrate binding site [chemical binding]; other site
1157951002157	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1157951002158	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1157951002159	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1157951002160	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1157951002161	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1157951002162	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1157951002163	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1157951002164	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1157951002165	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1157951002166	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1157951002167	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1157951002168	cell division protein FtsL; Provisional; Region: PRK10772
1157951002169	MraW methylase family; Region: Methyltransf_5; pfam01795
1157951002170	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1157951002171	cell division protein MraZ; Reviewed; Region: PRK00326
1157951002172	MraZ protein; Region: MraZ; pfam02381
1157951002173	MraZ protein; Region: MraZ; pfam02381
1157951002174	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1157951002175	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951002176	DNA binding site [nucleotide binding]
1157951002177	domain linker motif; other site
1157951002178	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1157951002179	dimerization interface [polypeptide binding]; other site
1157951002180	ligand binding site [chemical binding]; other site
1157951002181	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1157951002182	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1157951002183	putative valine binding site [chemical binding]; other site
1157951002184	dimer interface [polypeptide binding]; other site
1157951002185	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1157951002186	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1157951002187	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1157951002188	PYR/PP interface [polypeptide binding]; other site
1157951002189	dimer interface [polypeptide binding]; other site
1157951002190	TPP binding site [chemical binding]; other site
1157951002191	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951002192	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1157951002193	TPP-binding site [chemical binding]; other site
1157951002194	dimer interface [polypeptide binding]; other site
1157951002195	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1157951002196	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1157951002197	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1157951002198	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1157951002199	acyl-activating enzyme (AAE) consensus motif; other site
1157951002200	acyl-activating enzyme (AAE) consensus motif; other site
1157951002201	putative AMP binding site [chemical binding]; other site
1157951002202	putative active site [active]
1157951002203	putative CoA binding site [chemical binding]; other site
1157951002204	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1157951002205	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951002206	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1157951002207	putative substrate binding pocket [chemical binding]; other site
1157951002208	putative dimerization interface [polypeptide binding]; other site
1157951002209	2-isopropylmalate synthase; Validated; Region: PRK00915
1157951002210	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1157951002211	active site
1157951002212	catalytic residues [active]
1157951002213	metal binding site [ion binding]; metal-binding site
1157951002214	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1157951002215	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1157951002216	tartrate dehydrogenase; Region: TTC; TIGR02089
1157951002217	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1157951002218	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1157951002219	substrate binding site [chemical binding]; other site
1157951002220	ligand binding site [chemical binding]; other site
1157951002221	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1157951002222	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1157951002223	substrate binding site [chemical binding]; other site
1157951002224	transcriptional regulator SgrR; Provisional; Region: PRK13626
1157951002225	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1157951002226	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1157951002227	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1157951002228	putative DNA-binding cleft [nucleotide binding]; other site
1157951002229	putative DNA clevage site; other site
1157951002230	molecular lever; other site
1157951002231	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
1157951002232	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1157951002233	Neutral sphingomyelinases (nSMase) catalyze the hydrolysis of sphingomyelin in biological membranes to ceramide and phosphorylcholine; Region: nSMase; cd09078
1157951002234	putative catalytic site [active]
1157951002235	metal binding site A [ion binding]; metal-binding site
1157951002236	phosphate binding site [ion binding]; other site
1157951002237	metal binding site C [ion binding]; metal-binding site
1157951002238	metal binding site B [ion binding]; metal-binding site
1157951002239	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1157951002240	acetoin reductases; Region: 23BDH; TIGR02415
1157951002241	NAD(P) binding site [chemical binding]; other site
1157951002242	active site
1157951002243	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1157951002244	agmatinase; Region: agmatinase; TIGR01230
1157951002245	oligomer interface [polypeptide binding]; other site
1157951002246	putative active site [active]
1157951002247	Mn binding site [ion binding]; other site
1157951002248	arginine decarboxylase; Provisional; Region: PRK05354
1157951002249	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1157951002250	dimer interface [polypeptide binding]; other site
1157951002251	active site
1157951002252	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1157951002253	catalytic residues [active]
1157951002254	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1157951002255	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1157951002256	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1157951002257	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1157951002258	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1157951002259	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951002260	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951002261	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951002262	dimerization interface [polypeptide binding]; other site
1157951002263	N-terminal Early set domain associated with the catalytic domain of chitinase; Region: E_set_Chitinase_N; cd02848
1157951002264	Glyco_18 domain; Region: Glyco_18; smart00636
1157951002265	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1157951002266	active site
1157951002267	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1157951002268	Predicted transporter component [General function prediction only]; Region: COG2391
1157951002269	Sulphur transport; Region: Sulf_transp; pfam04143
1157951002270	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
1157951002271	Predicted transporter component [General function prediction only]; Region: COG2391
1157951002272	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1157951002273	dimerization interface [polypeptide binding]; other site
1157951002274	putative DNA binding site [nucleotide binding]; other site
1157951002275	putative Zn2+ binding site [ion binding]; other site
1157951002276	hypothetical protein; Provisional; Region: PRK04860
1157951002277	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1157951002278	FOG: CBS domain [General function prediction only]; Region: COG0517
1157951002279	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1157951002280	Divalent cation transporter; Region: MgtE; pfam01769
1157951002281	HEAT repeats; Region: HEAT_2; pfam13646
1157951002282	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1157951002283	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1157951002284	FAD binding pocket [chemical binding]; other site
1157951002285	FAD binding motif [chemical binding]; other site
1157951002286	phosphate binding motif [ion binding]; other site
1157951002287	beta-alpha-beta structure motif; other site
1157951002288	NAD binding pocket [chemical binding]; other site
1157951002289	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1157951002290	catalytic loop [active]
1157951002291	iron binding site [ion binding]; other site
1157951002292	hybrid cluster protein; Provisional; Region: PRK05290
1157951002293	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1157951002294	ACS interaction site; other site
1157951002295	CODH interaction site; other site
1157951002296	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1157951002297	hybrid metal cluster; other site
1157951002298	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1157951002299	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1157951002300	trimer interface [polypeptide binding]; other site
1157951002301	eyelet of channel; other site
1157951002302	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1157951002303	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1157951002304	Cl- selectivity filter; other site
1157951002305	Cl- binding residues [ion binding]; other site
1157951002306	pore gating glutamate residue; other site
1157951002307	dimer interface [polypeptide binding]; other site
1157951002308	H+/Cl- coupling transport residue; other site
1157951002309	tellurite resistance protein TehB; Provisional; Region: PRK12335
1157951002310	Domain of unknown function (DUF1971); Region: DUF1971; cl17717
1157951002311	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951002312	S-adenosylmethionine binding site [chemical binding]; other site
1157951002313	Choloylglycine hydrolase (CGH) is a bile salt-modifying enzyme that hydrolyzes non-peptide carbon-nitrogen bonds in choloylglycine and choloyltaurine, both of which are present in bile.  CGH is present in a number of probiotic microbial organisms that...; Region: Ntn_CGH; cd01902
1157951002314	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1157951002315	hypothetical protein; Provisional; Region: PRK03757
1157951002316	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1157951002317	GST_N family, unknown subfamily 1; composed of uncharacterized proteins, predominantly from bacteria, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; Region: GST_N_1; cd03043
1157951002318	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1157951002319	putative C-terminal domain interface [polypeptide binding]; other site
1157951002320	putative GSH binding site (G-site) [chemical binding]; other site
1157951002321	putative dimer interface [polypeptide binding]; other site
1157951002322	C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases; Region: GST_C_3; cd03194
1157951002323	putative N-terminal domain interface [polypeptide binding]; other site
1157951002324	putative dimer interface [polypeptide binding]; other site
1157951002325	putative substrate binding pocket (H-site) [chemical binding]; other site
1157951002326	phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK01293; cl07913
1157951002327	Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620
1157951002328	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1157951002329	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1157951002330	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1157951002331	NAD binding site [chemical binding]; other site
1157951002332	substrate binding site [chemical binding]; other site
1157951002333	putative active site [active]
1157951002334	Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_1; cd09996
1157951002335	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
1157951002336	active site
1157951002337	Zn binding site [ion binding]; other site
1157951002338	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1157951002339	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1157951002340	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1157951002341	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1157951002342	substrate binding site [chemical binding]; other site
1157951002343	ATP binding site [chemical binding]; other site
1157951002344	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
1157951002345	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
1157951002346	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1157951002347	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1157951002348	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1157951002349	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1157951002350	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1157951002351	active site
1157951002352	catalytic site [active]
1157951002353	substrate binding site [chemical binding]; other site
1157951002354	Predicted signal-transduction protein containing cAMP-binding and CBS domains [Signal transduction mechanisms]; Region: COG2905
1157951002355	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1157951002356	ligand binding site [chemical binding]; other site
1157951002357	flexible hinge region; other site
1157951002358	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with either the CAP_ED (cAMP receptor protein effector domain) family of transcription factors and the DUF294 domain or the PB1 (Phox and Bem1p) domain; Region: CBS_pair_CAP-ED_DUF294_PBI_assoc2; cd04800
1157951002359	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1157951002360	metal binding triad; other site
1157951002361	putative transporter; Provisional; Region: PRK10484
1157951002362	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
1157951002363	Na binding site [ion binding]; other site
1157951002364	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1157951002365	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1157951002366	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1157951002367	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1157951002368	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1157951002369	PYR/PP interface [polypeptide binding]; other site
1157951002370	dimer interface [polypeptide binding]; other site
1157951002371	TPP binding site [chemical binding]; other site
1157951002372	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951002373	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1157951002374	TPP-binding site; other site
1157951002375	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1157951002376	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1157951002377	tetrameric interface [polypeptide binding]; other site
1157951002378	NAD binding site [chemical binding]; other site
1157951002379	catalytic residues [active]
1157951002380	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1157951002381	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1157951002382	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1157951002383	putative active site [active]
1157951002384	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951002385	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951002386	non-specific DNA binding site [nucleotide binding]; other site
1157951002387	salt bridge; other site
1157951002388	sequence-specific DNA binding site [nucleotide binding]; other site
1157951002389	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1157951002390	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1157951002391	ligand binding site; other site
1157951002392	oligomer interface; other site
1157951002393	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1157951002394	dimer interface [polypeptide binding]; other site
1157951002395	N-terminal domain interface [polypeptide binding]; other site
1157951002396	sulfate 1 binding site; other site
1157951002397	glycogen phosphorylase; Provisional; Region: PRK14986
1157951002398	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1157951002399	homodimer interface [polypeptide binding]; other site
1157951002400	active site pocket [active]
1157951002401	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1157951002402	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951002403	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1157951002404	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1157951002405	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951002406	putative substrate translocation pore; other site
1157951002407	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951002408	TonB-dependent copper receptor; Region: TonB-copper; TIGR01778
1157951002409	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951002410	N-terminal plug; other site
1157951002411	ligand-binding site [chemical binding]; other site
1157951002412	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1157951002413	active site
1157951002414	substrate binding pocket [chemical binding]; other site
1157951002415	homodimer interaction site [polypeptide binding]; other site
1157951002416	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1157951002417	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1157951002418	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1157951002419	potential frameshift: common BLAST hit: gi|197285387|ref|YP_002151259.1| carbohydrate kinase
1157951002420	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1157951002421	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1157951002422	substrate binding site [chemical binding]; other site
1157951002423	dimer interface [polypeptide binding]; other site
1157951002424	ATP binding site [chemical binding]; other site
1157951002425	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1157951002426	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1157951002427	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1157951002428	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1157951002429	binding surface
1157951002430	TPR motif; other site
1157951002431	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
1157951002432	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1157951002433	catalytic residues [active]
1157951002434	central insert; other site
1157951002435	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1157951002436	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
1157951002437	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
1157951002438	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1157951002439	heme exporter protein CcmC; Region: ccmC; TIGR01191
1157951002440	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1157951002441	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1157951002442	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1157951002443	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1157951002444	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1157951002445	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1157951002446	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1157951002447	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1157951002448	[4Fe-4S] binding site [ion binding]; other site
1157951002449	molybdopterin cofactor binding site; other site
1157951002450	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1157951002451	molybdopterin cofactor binding site; other site
1157951002452	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1157951002453	ferredoxin-type protein; Provisional; Region: PRK10194
1157951002454	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1157951002455	cytochrome c nitrite reductase, pentaheme subunit; Region: cyt_nit_nrfB; TIGR03146
1157951002456	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1157951002457	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1157951002458	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1157951002459	heme lyase subunit NrfE; Provisional; Region: PRK10369
1157951002460	Cytochrome C biogenesis protein; Region: CcmH; cl01179
1157951002461	TPR repeat; Region: TPR_11; pfam13414
1157951002462	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1157951002463	TPR motif; other site
1157951002464	binding surface
1157951002465	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1157951002466	beta-galactosidase; Region: BGL; TIGR03356
1157951002467	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1157951002468	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1157951002469	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1157951002470	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1157951002471	putative acyl-acceptor binding pocket; other site
1157951002472	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1157951002473	ArsC family; Region: ArsC; pfam03960
1157951002474	catalytic residues [active]
1157951002475	arsenical pump membrane protein; Provisional; Region: PRK15445
1157951002476	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1157951002477	transmembrane helices; other site
1157951002478	arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291
1157951002479	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1157951002480	P loop; other site
1157951002481	Nucleotide binding site [chemical binding]; other site
1157951002482	DTAP/Switch II; other site
1157951002483	Switch I; other site
1157951002484	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1157951002485	P loop; other site
1157951002486	Nucleotide binding site [chemical binding]; other site
1157951002487	DTAP/Switch II; other site
1157951002488	Switch I; other site
1157951002489	Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953
1157951002490	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1157951002491	dimerization interface [polypeptide binding]; other site
1157951002492	putative DNA binding site [nucleotide binding]; other site
1157951002493	putative Zn2+ binding site [ion binding]; other site
1157951002494	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1157951002495	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951002496	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1157951002497	active site
1157951002498	DNA binding site [nucleotide binding]
1157951002499	Int/Topo IB signature motif; other site
1157951002500	DinI-like family; Region: DinI; cl11630
1157951002501	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951002502	non-specific DNA binding site [nucleotide binding]; other site
1157951002503	salt bridge; other site
1157951002504	sequence-specific DNA binding site [nucleotide binding]; other site
1157951002505	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1157951002506	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1157951002507	Fibronectin type III protein; Region: DUF3672; pfam12421
1157951002508	Phage-related minor tail protein [Function unknown]; Region: COG5281
1157951002509	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
1157951002510	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
1157951002511	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
1157951002512	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
1157951002513	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
1157951002514	oligomerization interface [polypeptide binding]; other site
1157951002515	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1157951002516	Phage capsid family; Region: Phage_capsid; pfam05065
1157951002517	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1157951002518	oligomer interface [polypeptide binding]; other site
1157951002519	Clp protease; Region: CLP_protease; pfam00574
1157951002520	active site residues [active]
1157951002521	Phage-related protein [Function unknown]; Region: COG4695
1157951002522	Phage portal protein; Region: Phage_portal; pfam04860
1157951002523	Phage Terminase; Region: Terminase_1; pfam03354
1157951002524	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1157951002525	active site
1157951002526	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
1157951002527	protein binding surface [polypeptide binding]; other site
1157951002528	HEAT-like repeat; Region: HEAT_EZ; pfam13513
1157951002529	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1157951002530	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1157951002531	Protein of unknown function (DUF754); Region: DUF754; pfam05449
1157951002532	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cl00365
1157951002533	Antitermination protein; Region: Antiterm; pfam03589
1157951002534	Antitermination protein; Region: Antiterm; pfam03589
1157951002535	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1157951002536	active site
1157951002537	metal binding site [ion binding]; metal-binding site
1157951002538	interdomain interaction site; other site
1157951002539	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1157951002540	Walker A motif; other site
1157951002541	ATP binding site [chemical binding]; other site
1157951002542	AAA domain; Region: AAA_25; pfam13481
1157951002543	Walker B motif; other site
1157951002544	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1157951002545	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951002546	non-specific DNA binding site [nucleotide binding]; other site
1157951002547	Predicted transcriptional regulator [Transcription]; Region: COG2932
1157951002548	salt bridge; other site
1157951002549	sequence-specific DNA binding site [nucleotide binding]; other site
1157951002550	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1157951002551	Catalytic site [active]
1157951002552	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951002553	non-specific DNA binding site [nucleotide binding]; other site
1157951002554	salt bridge; other site
1157951002555	sequence-specific DNA binding site [nucleotide binding]; other site
1157951002556	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3646
1157951002557	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1157951002558	Restriction alleviation protein Lar; Region: Lar_restr_allev; pfam14354
1157951002559	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1157951002560	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1157951002561	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1157951002562	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1157951002563	homodimer interface [polypeptide binding]; other site
1157951002564	NADP binding site [chemical binding]; other site
1157951002565	substrate binding site [chemical binding]; other site
1157951002566	ribosome-associated protein; Provisional; Region: PRK11507
1157951002567	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951002568	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951002569	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951002570	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951002571	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951002572	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951002573	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951002574	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951002575	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951002576	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951002577	Fimbrial protein; Region: Fimbrial; pfam00419
1157951002578	Fimbrial protein; Region: Fimbrial; pfam00419
1157951002579	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951002580	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951002581	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951002582	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1157951002583	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1157951002584	active site
1157951002585	HIGH motif; other site
1157951002586	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1157951002587	KMSKS motif; other site
1157951002588	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1157951002589	tRNA binding surface [nucleotide binding]; other site
1157951002590	anticodon binding site; other site
1157951002591	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1157951002592	substrate binding site [chemical binding]; other site
1157951002593	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1157951002594	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1157951002595	putative active site [active]
1157951002596	putative metal binding site [ion binding]; other site
1157951002597	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1157951002598	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1157951002599	ATP-grasp domain; Region: ATP-grasp; pfam02222
1157951002600	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951002601	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1157951002602	putative substrate translocation pore; other site
1157951002603	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4222
1157951002604	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1157951002605	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1157951002606	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1157951002607	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1157951002608	Walker A/P-loop; other site
1157951002609	ATP binding site [chemical binding]; other site
1157951002610	Q-loop/lid; other site
1157951002611	ABC transporter signature motif; other site
1157951002612	Walker B; other site
1157951002613	D-loop; other site
1157951002614	H-loop/switch region; other site
1157951002615	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1157951002616	active site
1157951002617	catalytic triad [active]
1157951002618	oxyanion hole [active]
1157951002619	switch loop; other site
1157951002620	oxidoreductase; Provisional; Region: PRK08017
1157951002621	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1157951002622	NADP binding site [chemical binding]; other site
1157951002623	active site
1157951002624	steroid binding site; other site
1157951002625	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1157951002626	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1157951002627	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1157951002628	binding surface
1157951002629	TPR motif; other site
1157951002630	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1157951002631	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1157951002632	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1157951002633	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1157951002634	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1157951002635	DNA binding residues [nucleotide binding]
1157951002636	dimer interface [polypeptide binding]; other site
1157951002637	copper binding site [ion binding]; other site
1157951002638	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1157951002639	metal-binding site [ion binding]
1157951002640	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1157951002641	metal-binding site [ion binding]
1157951002642	copper exporting ATPase; Provisional; Region: copA; PRK10671
1157951002643	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1157951002644	metal-binding site [ion binding]
1157951002645	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1157951002646	metal-binding site [ion binding]
1157951002647	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1157951002648	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951002649	motif II; other site
1157951002650	TraB family; Region: TraB; cl12050
1157951002651	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1157951002652	putative deacylase active site [active]
1157951002653	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
1157951002654	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
1157951002655	active site
1157951002656	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1157951002657	active site
1157951002658	NTP binding site [chemical binding]; other site
1157951002659	metal binding triad [ion binding]; metal-binding site
1157951002660	antibiotic binding site [chemical binding]; other site
1157951002661	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1157951002662	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1157951002663	active site
1157951002664	metal binding site [ion binding]; metal-binding site
1157951002665	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1157951002666	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951002667	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951002668	putative cation:proton antiport protein; Provisional; Region: PRK10669
1157951002669	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1157951002670	TrkA-N domain; Region: TrkA_N; pfam02254
1157951002671	inosine/guanosine kinase; Provisional; Region: PRK15074
1157951002672	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1157951002673	substrate binding site [chemical binding]; other site
1157951002674	ATP binding site [chemical binding]; other site
1157951002675	LPS O-antigen length regulator; Provisional; Region: PRK10381
1157951002676	Chain length determinant protein; Region: Wzz; cl15801
1157951002677	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1157951002678	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1157951002679	ferrochelatase; Reviewed; Region: hemH; PRK00035
1157951002680	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1157951002681	C-terminal domain interface [polypeptide binding]; other site
1157951002682	active site
1157951002683	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1157951002684	active site
1157951002685	N-terminal domain interface [polypeptide binding]; other site
1157951002686	adenylate kinase; Reviewed; Region: adk; PRK00279
1157951002687	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1157951002688	AMP-binding site [chemical binding]; other site
1157951002689	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1157951002690	heat shock protein 90; Provisional; Region: PRK05218
1157951002691	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951002692	ATP binding site [chemical binding]; other site
1157951002693	Mg2+ binding site [ion binding]; other site
1157951002694	G-X-G motif; other site
1157951002695	recombination protein RecR; Reviewed; Region: recR; PRK00076
1157951002696	RecR protein; Region: RecR; pfam02132
1157951002697	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1157951002698	putative active site [active]
1157951002699	putative metal-binding site [ion binding]; other site
1157951002700	tetramer interface [polypeptide binding]; other site
1157951002701	hypothetical protein; Validated; Region: PRK00153
1157951002702	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1157951002703	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951002704	Walker A motif; other site
1157951002705	ATP binding site [chemical binding]; other site
1157951002706	Walker B motif; other site
1157951002707	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1157951002708	arginine finger; other site
1157951002709	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1157951002710	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1157951002711	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1157951002712	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951002713	active site
1157951002714	Primosomal replication protein priB and priC; Region: priB_priC; cl11483
1157951002715	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1157951002716	Protein of unknown function (DUF2496); Region: DUF2496; cl11670
1157951002717	hypothetical protein; Provisional; Region: PRK11281
1157951002718	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1157951002719	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1157951002720	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1157951002721	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1157951002722	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951002723	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1157951002724	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1157951002725	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951002726	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951002727	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1157951002728	Protein export membrane protein; Region: SecD_SecF; cl14618
1157951002729	Protein export membrane protein; Region: SecD_SecF; cl14618
1157951002730	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1157951002731	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1157951002732	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1157951002733	transmembrane helices; other site
1157951002734	enolase; Provisional; Region: eno; PRK00077
1157951002735	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1157951002736	dimer interface [polypeptide binding]; other site
1157951002737	metal binding site [ion binding]; metal-binding site
1157951002738	substrate binding pocket [chemical binding]; other site
1157951002739	CTP synthetase; Validated; Region: pyrG; PRK05380
1157951002740	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1157951002741	Catalytic site [active]
1157951002742	active site
1157951002743	UTP binding site [chemical binding]; other site
1157951002744	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1157951002745	active site
1157951002746	putative oxyanion hole; other site
1157951002747	catalytic triad [active]
1157951002748	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951002749	ABC transporter signature motif; other site
1157951002750	Walker B; other site
1157951002751	D-loop; other site
1157951002752	H-loop/switch region; other site
1157951002753	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1157951002754	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1157951002755	homodimer interface [polypeptide binding]; other site
1157951002756	metal binding site [ion binding]; metal-binding site
1157951002757	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1157951002758	homodimer interface [polypeptide binding]; other site
1157951002759	active site
1157951002760	putative chemical substrate binding site [chemical binding]; other site
1157951002761	metal binding site [ion binding]; metal-binding site
1157951002762	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1157951002763	HD domain; Region: HD_4; pfam13328
1157951002764	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1157951002765	synthetase active site [active]
1157951002766	NTP binding site [chemical binding]; other site
1157951002767	metal binding site [ion binding]; metal-binding site
1157951002768	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1157951002769	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1157951002770	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1157951002771	TRAM domain; Region: TRAM; pfam01938
1157951002772	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951002773	S-adenosylmethionine binding site [chemical binding]; other site
1157951002774	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1157951002775	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; smart00471
1157951002776	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1157951002777	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1157951002778	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1157951002779	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1157951002780	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1157951002781	cobalamin binding residues [chemical binding]; other site
1157951002782	putative BtuC binding residues; other site
1157951002783	dimer interface [polypeptide binding]; other site
1157951002784	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1157951002785	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1157951002786	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1157951002787	inhibitor-cofactor binding pocket; inhibition site
1157951002788	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951002789	catalytic residue [active]
1157951002790	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1157951002791	Transglycosylase; Region: Transgly; pfam00912
1157951002792	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1157951002793	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1157951002794	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1157951002795	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951002796	ATP binding site [chemical binding]; other site
1157951002797	putative Mg++ binding site [ion binding]; other site
1157951002798	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951002799	nucleotide binding region [chemical binding]; other site
1157951002800	ATP-binding site [chemical binding]; other site
1157951002801	Helicase associated domain (HA2); Region: HA2; pfam04408
1157951002802	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1157951002803	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1157951002804	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1157951002805	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1157951002806	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1157951002807	active site
1157951002808	nucleotide binding site [chemical binding]; other site
1157951002809	HIGH motif; other site
1157951002810	KMSKS motif; other site
1157951002811	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1157951002812	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1157951002813	active site
1157951002814	NTP binding site [chemical binding]; other site
1157951002815	metal binding triad [ion binding]; metal-binding site
1157951002816	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1157951002817	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1157951002818	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1157951002819	catalytic center binding site [active]
1157951002820	ATP binding site [chemical binding]; other site
1157951002821	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1157951002822	oligomerization interface [polypeptide binding]; other site
1157951002823	active site
1157951002824	metal binding site [ion binding]; metal-binding site
1157951002825	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1157951002826	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1157951002827	active site
1157951002828	ATP-binding site [chemical binding]; other site
1157951002829	pantoate-binding site; other site
1157951002830	HXXH motif; other site
1157951002831	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1157951002832	tetramerization interface [polypeptide binding]; other site
1157951002833	active site
1157951002834	Fimbrial protein; Region: Fimbrial; pfam00419
1157951002835	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951002836	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951002837	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951002838	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951002839	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1157951002840	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951002841	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951002842	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951002843	Fimbrial protein; Region: Fimbrial; pfam00419
1157951002844	Fimbrial protein; Region: Fimbrial; cl01416
1157951002845	Fimbrial protein; Region: Fimbrial; pfam00419
1157951002846	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951002847	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951002848	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951002849	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951002850	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951002851	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1157951002852	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951002853	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951002854	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951002855	inner membrane transport permease; Provisional; Region: PRK15066
1157951002856	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1157951002857	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1157951002858	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1157951002859	Walker A/P-loop; other site
1157951002860	ATP binding site [chemical binding]; other site
1157951002861	Q-loop/lid; other site
1157951002862	ABC transporter signature motif; other site
1157951002863	Walker B; other site
1157951002864	D-loop; other site
1157951002865	H-loop/switch region; other site
1157951002866	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1157951002867	active site clefts [active]
1157951002868	zinc binding site [ion binding]; other site
1157951002869	dimer interface [polypeptide binding]; other site
1157951002870	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951002871	active site
1157951002872	multicopper oxidase; Provisional; Region: PRK10965
1157951002873	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1157951002874	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1157951002875	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1157951002876	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1157951002877	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1157951002878	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1157951002879	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1157951002880	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951002881	Coenzyme A binding pocket [chemical binding]; other site
1157951002882	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1157951002883	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951002884	hypothetical protein; Provisional; Region: PRK02399
1157951002885	Uncharacterized protein family (UPF0261); Region: UPF0261; pfam06792
1157951002886	TIM-barrel signal transduction protein; Region: TIM-br_sig_trns; pfam09370
1157951002887	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
1157951002888	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1157951002889	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1157951002890	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1157951002891	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1157951002892	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951002893	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951002894	non-specific DNA binding site [nucleotide binding]; other site
1157951002895	salt bridge; other site
1157951002896	sequence-specific DNA binding site [nucleotide binding]; other site
1157951002897	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1157951002898	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1157951002899	P-loop, Walker A motif; other site
1157951002900	Base recognition motif; other site
1157951002901	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1157951002902	Uncharacterized small protein [Function unknown]; Region: COG2879
1157951002903	carbon starvation protein A; Provisional; Region: PRK15015
1157951002904	Carbon starvation protein CstA; Region: CstA; pfam02554
1157951002905	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1157951002906	choline dehydrogenase; Validated; Region: PRK02106
1157951002907	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1157951002908	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1157951002909	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1157951002910	ATP-grasp domain; Region: ATP-grasp; pfam02222
1157951002911	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1157951002912	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
1157951002913	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1157951002914	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1157951002915	putative substrate binding site [chemical binding]; other site
1157951002916	putative ATP binding site [chemical binding]; other site
1157951002917	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1157951002918	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1157951002919	substrate binding [chemical binding]; other site
1157951002920	active site
1157951002921	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1157951002922	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1157951002923	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951002924	DNA binding site [nucleotide binding]
1157951002925	domain linker motif; other site
1157951002926	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
1157951002927	putative dimerization interface [polypeptide binding]; other site
1157951002928	putative ligand binding site [chemical binding]; other site
1157951002929	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1157951002930	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1157951002931	DNA binding residues [nucleotide binding]
1157951002932	dimerization interface [polypeptide binding]; other site
1157951002933	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
1157951002934	dihydroxyacetone kinase, phosphotransfer subunit; Region: dha_pts; TIGR02364
1157951002935	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1157951002936	dimerization domain swap beta strand [polypeptide binding]; other site
1157951002937	regulatory protein interface [polypeptide binding]; other site
1157951002938	active site
1157951002939	regulatory phosphorylation site [posttranslational modification]; other site
1157951002940	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1157951002941	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1157951002942	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1157951002943	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1157951002944	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1157951002945	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951002946	FeS/SAM binding site; other site
1157951002947	TRAM domain; Region: TRAM; cl01282
1157951002948	Fe2+ transport protein; Region: Iron_transport; pfam10634
1157951002949	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1157951002950	Iron permease FTR1 family; Region: FTR1; cl00475
1157951002951	Imelysin; Region: Peptidase_M75; pfam09375
1157951002952	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1157951002953	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1157951002954	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
1157951002955	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
1157951002956	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
1157951002957	active site
1157951002958	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
1157951002959	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951002960	Sel1-like repeats; Region: SEL1; smart00671
1157951002961	Sel1-like repeats; Region: SEL1; smart00671
1157951002962	Sel1-like repeats; Region: SEL1; smart00671
1157951002963	Sel1-like repeats; Region: SEL1; smart00671
1157951002964	Sel1-like repeats; Region: SEL1; smart00671
1157951002965	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1157951002966	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1157951002967	metal ion-dependent adhesion site (MIDAS); other site
1157951002968	Predicted small integral membrane protein (DUF2165); Region: DUF2165; pfam09933
1157951002969	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951002970	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951002971	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1157951002972	dimerization interface [polypeptide binding]; other site
1157951002973	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1157951002974	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1157951002975	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1157951002976	active site
1157951002977	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1157951002978	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1157951002979	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1157951002980	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1157951002981	homotrimer interaction site [polypeptide binding]; other site
1157951002982	putative active site [active]
1157951002983	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1157951002984	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951002985	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951002986	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1157951002987	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1157951002988	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951002989	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951002990	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951002991	putative substrate translocation pore; other site
1157951002992	tetracycline repressor protein TetR; Provisional; Region: PRK13756
1157951002993	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951002994	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
1157951002995	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1157951002996	dimerization interface [polypeptide binding]; other site
1157951002997	putative DNA binding site [nucleotide binding]; other site
1157951002998	putative Zn2+ binding site [ion binding]; other site
1157951002999	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1157951003000	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1157951003001	Sodium/glutamate symporter; Region: Glt_symporter; pfam03616
1157951003002	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1157951003003	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951003004	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951003005	dimerization interface [polypeptide binding]; other site
1157951003006	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1157951003007	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1157951003008	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1157951003009	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1157951003010	homotrimer interaction site [polypeptide binding]; other site
1157951003011	putative active site [active]
1157951003012	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1157951003013	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
1157951003014	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1157951003015	dimer interface [polypeptide binding]; other site
1157951003016	PYR/PP interface [polypeptide binding]; other site
1157951003017	TPP binding site [chemical binding]; other site
1157951003018	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951003019	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1157951003020	TPP-binding site [chemical binding]; other site
1157951003021	dimer interface [polypeptide binding]; other site
1157951003022	Domain of unknown function (DUF1795); Region: DUF1795; pfam08786
1157951003023	PAAR motif; Region: PAAR_motif; pfam05488
1157951003024	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1157951003025	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1157951003026	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1157951003027	RHS Repeat; Region: RHS_repeat; pfam05593
1157951003028	RHS protein; Region: RHS; pfam03527
1157951003029	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951003030	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951003031	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951003032	A nuclease family of the HNH/ENDO VII superfamily with conserved AHH; Region: AHH; pfam14412
1157951003033	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951003034	Transposase; Region: HTH_Tnp_1; pfam01527
1157951003035	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1157951003036	Integrase core domain; Region: rve; pfam00665
1157951003037	Integrase core domain; Region: rve_3; pfam13683
1157951003038	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1157951003039	MutS domain I; Region: MutS_I; pfam01624
1157951003040	MutS domain II; Region: MutS_II; pfam05188
1157951003041	MutS domain III; Region: MutS_III; pfam05192
1157951003042	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1157951003043	Walker A/P-loop; other site
1157951003044	ATP binding site [chemical binding]; other site
1157951003045	Q-loop/lid; other site
1157951003046	ABC transporter signature motif; other site
1157951003047	Walker B; other site
1157951003048	D-loop; other site
1157951003049	H-loop/switch region; other site
1157951003050	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1157951003051	active site
1157951003052	dinuclear metal binding site [ion binding]; other site
1157951003053	dimerization interface [polypeptide binding]; other site
1157951003054	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1157951003055	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1157951003056	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1157951003057	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1157951003058	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1157951003059	DNA binding residues [nucleotide binding]
1157951003060	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1157951003061	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1157951003062	Peptidase family M23; Region: Peptidase_M23; pfam01551
1157951003063	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1157951003064	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951003065	S-adenosylmethionine binding site [chemical binding]; other site
1157951003066	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1157951003067	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1157951003068	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1157951003069	Permutation of conserved domain; other site
1157951003070	active site
1157951003071	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1157951003072	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1157951003073	homotrimer interaction site [polypeptide binding]; other site
1157951003074	zinc binding site [ion binding]; other site
1157951003075	CDP-binding sites; other site
1157951003076	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1157951003077	substrate binding site; other site
1157951003078	dimer interface; other site
1157951003079	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1157951003080	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1157951003081	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1157951003082	ligand-binding site [chemical binding]; other site
1157951003083	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1157951003084	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1157951003085	CysD dimerization site [polypeptide binding]; other site
1157951003086	G1 box; other site
1157951003087	putative GEF interaction site [polypeptide binding]; other site
1157951003088	GTP/Mg2+ binding site [chemical binding]; other site
1157951003089	Switch I region; other site
1157951003090	G2 box; other site
1157951003091	G3 box; other site
1157951003092	Switch II region; other site
1157951003093	G4 box; other site
1157951003094	G5 box; other site
1157951003095	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1157951003096	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1157951003097	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1157951003098	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1157951003099	Active Sites [active]
1157951003100	siroheme synthase; Provisional; Region: cysG; PRK10637
1157951003101	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1157951003102	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1157951003103	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1157951003104	active site
1157951003105	SAM binding site [chemical binding]; other site
1157951003106	homodimer interface [polypeptide binding]; other site
1157951003107	trehalose repressor; Provisional; Region: treR; PRK09492
1157951003108	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951003109	DNA binding site [nucleotide binding]
1157951003110	domain linker motif; other site
1157951003111	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1157951003112	dimerization interface [polypeptide binding]; other site
1157951003113	ligand binding site [chemical binding]; other site
1157951003114	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1157951003115	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1157951003116	active site turn [active]
1157951003117	phosphorylation site [posttranslational modification]
1157951003118	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1157951003119	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
1157951003120	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1157951003121	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1157951003122	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1157951003123	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1157951003124	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1157951003125	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951003126	motif II; other site
1157951003127	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1157951003128	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1157951003129	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1157951003130	Active Sites [active]
1157951003131	sulfite reductase subunit beta; Provisional; Region: PRK13504
1157951003132	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1157951003133	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1157951003134	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1157951003135	Flavodoxin; Region: Flavodoxin_1; pfam00258
1157951003136	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1157951003137	FAD binding pocket [chemical binding]; other site
1157951003138	FAD binding motif [chemical binding]; other site
1157951003139	catalytic residues [active]
1157951003140	NAD binding pocket [chemical binding]; other site
1157951003141	phosphate binding motif [ion binding]; other site
1157951003142	beta-alpha-beta structure motif; other site
1157951003143	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1157951003144	active site
1157951003145	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1157951003146	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1157951003147	putative proline-specific permease; Provisional; Region: proY; PRK10580
1157951003148	methionine gamma-lyase; Provisional; Region: PRK07503
1157951003149	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1157951003150	homodimer interface [polypeptide binding]; other site
1157951003151	substrate-cofactor binding pocket; other site
1157951003152	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951003153	catalytic residue [active]
1157951003154	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1157951003155	hypothetical protein; Provisional; Region: PRK05421
1157951003156	putative catalytic site [active]
1157951003157	putative metal binding site [ion binding]; other site
1157951003158	putative phosphate binding site [ion binding]; other site
1157951003159	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951003160	Walker B motif; other site
1157951003161	arginine finger; other site
1157951003162	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951003163	Walker A motif; other site
1157951003164	ATP binding site [chemical binding]; other site
1157951003165	Walker B motif; other site
1157951003166	arginine finger; other site
1157951003167	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1157951003168	Clp amino terminal domain; Region: Clp_N; pfam02861
1157951003169	Clp amino terminal domain; Region: Clp_N; pfam02861
1157951003170	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951003171	Walker A motif; other site
1157951003172	ATP binding site [chemical binding]; other site
1157951003173	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
1157951003174	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1157951003175	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1157951003176	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1157951003177	RNA binding surface [nucleotide binding]; other site
1157951003178	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1157951003179	active site
1157951003180	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1157951003181	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1157951003182	30S subunit binding site; other site
1157951003183	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1157951003184	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1157951003185	Prephenate dehydratase; Region: PDT; pfam00800
1157951003186	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1157951003187	putative L-Phe binding site [chemical binding]; other site
1157951003188	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1157951003189	dimerization interface [polypeptide binding]; other site
1157951003190	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1157951003191	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1157951003192	dimer interface [polypeptide binding]; other site
1157951003193	putative CheW interface [polypeptide binding]; other site
1157951003194	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1157951003195	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
1157951003196	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1157951003197	prephenate dehydrogenase; Validated; Region: PRK08507
1157951003198	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1157951003199	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1157951003200	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1157951003201	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1157951003202	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1157951003203	RimM N-terminal domain; Region: RimM; pfam01782
1157951003204	PRC-barrel domain; Region: PRC; pfam05239
1157951003205	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1157951003206	signal recognition particle protein; Provisional; Region: PRK10867
1157951003207	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1157951003208	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1157951003209	P loop; other site
1157951003210	GTP binding site [chemical binding]; other site
1157951003211	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1157951003212	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1157951003213	hypothetical protein; Provisional; Region: PRK11573
1157951003214	Domain of unknown function DUF21; Region: DUF21; pfam01595
1157951003215	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1157951003216	Transporter associated domain; Region: CorC_HlyC; smart01091
1157951003217	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1157951003218	glutamate--cysteine ligase; Provisional; Region: PRK02107
1157951003219	carbon storage regulator; Provisional; Region: PRK01712
1157951003220	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1157951003221	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1157951003222	motif 1; other site
1157951003223	active site
1157951003224	motif 2; other site
1157951003225	motif 3; other site
1157951003226	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1157951003227	DHHA1 domain; Region: DHHA1; pfam02272
1157951003228	recombinase A; Provisional; Region: recA; PRK09354
1157951003229	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1157951003230	hexamer interface [polypeptide binding]; other site
1157951003231	Walker A motif; other site
1157951003232	ATP binding site [chemical binding]; other site
1157951003233	Walker B motif; other site
1157951003234	hypothetical protein; Validated; Region: PRK03661
1157951003235	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1157951003236	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951003237	putative substrate translocation pore; other site
1157951003238	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1157951003239	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1157951003240	putative acyl-acceptor binding pocket; other site
1157951003241	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1157951003242	acyl-activating enzyme (AAE) consensus motif; other site
1157951003243	putative AMP binding site [chemical binding]; other site
1157951003244	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1157951003245	Shikimate kinase; Region: SKI; pfam01202
1157951003246	magnesium binding site [ion binding]; other site
1157951003247	putative shikimate binding site; other site
1157951003248	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1157951003249	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1157951003250	putative catalytic cysteine [active]
1157951003251	gamma-glutamyl kinase; Provisional; Region: PRK05429
1157951003252	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1157951003253	nucleotide binding site [chemical binding]; other site
1157951003254	homotetrameric interface [polypeptide binding]; other site
1157951003255	putative phosphate binding site [ion binding]; other site
1157951003256	putative allosteric binding site; other site
1157951003257	PUA domain; Region: PUA; pfam01472
1157951003258	Transcriptional regulator Crl; Region: Crl; cl11653
1157951003259	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1157951003260	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951003261	active site
1157951003262	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1157951003263	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1157951003264	metal binding site [ion binding]; metal-binding site
1157951003265	dimer interface [polypeptide binding]; other site
1157951003266	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1157951003267	active site
1157951003268	DNA polymerase IV; Validated; Region: PRK02406
1157951003269	DNA binding site [nucleotide binding]
1157951003270	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1157951003271	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951003272	N-terminal plug; other site
1157951003273	ligand-binding site [chemical binding]; other site
1157951003274	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
1157951003275	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1157951003276	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1157951003277	DNA binding residues [nucleotide binding]
1157951003278	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1157951003279	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial protein Rv2277c and similar proteins; Region: GDPD_Rv2277c_like; cd08580
1157951003280	putative active site [active]
1157951003281	catalytic site [active]
1157951003282	putative metal binding site [ion binding]; other site
1157951003283	Protein of unknown function (DUF539); Region: DUF539; cl01129
1157951003284	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1157951003285	ApbE family; Region: ApbE; pfam02424
1157951003286	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
1157951003287	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1157951003288	catalytic loop [active]
1157951003289	iron binding site [ion binding]; other site
1157951003290	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
1157951003291	FAD binding pocket [chemical binding]; other site
1157951003292	FAD binding motif [chemical binding]; other site
1157951003293	phosphate binding motif [ion binding]; other site
1157951003294	beta-alpha-beta structure motif; other site
1157951003295	NAD binding pocket [chemical binding]; other site
1157951003296	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
1157951003297	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
1157951003298	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
1157951003299	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
1157951003300	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
1157951003301	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
1157951003302	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1157951003303	E3 interaction surface; other site
1157951003304	lipoyl attachment site [posttranslational modification]; other site
1157951003305	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
1157951003306	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1157951003307	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1157951003308	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1157951003309	putative active site [active]
1157951003310	putative dimer interface [polypeptide binding]; other site
1157951003311	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1157951003312	dimer interface [polypeptide binding]; other site
1157951003313	active site
1157951003314	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1157951003315	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1157951003316	active site
1157951003317	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1157951003318	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_3; cd06151
1157951003319	homotrimer interaction site [polypeptide binding]; other site
1157951003320	putative active site [active]
1157951003321	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1157951003322	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1157951003323	active site
1157951003324	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1157951003325	substrate binding site [chemical binding]; other site
1157951003326	catalytic residues [active]
1157951003327	dimer interface [polypeptide binding]; other site
1157951003328	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1157951003329	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951003330	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951003331	dimerization interface [polypeptide binding]; other site
1157951003332	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951003333	transcriptional activator TtdR; Provisional; Region: PRK09801
1157951003334	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1157951003335	putative effector binding pocket; other site
1157951003336	dimerization interface [polypeptide binding]; other site
1157951003337	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1157951003338	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
1157951003339	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
1157951003340	catalytic residues [active]
1157951003341	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1157951003342	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1157951003343	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1157951003344	RNA methyltransferase, RsmE family; Region: TIGR00046
1157951003345	glutathione synthetase; Provisional; Region: PRK05246
1157951003346	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1157951003347	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1157951003348	hypothetical protein; Validated; Region: PRK00228
1157951003349	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1157951003350	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1157951003351	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1157951003352	catalytic residue [active]
1157951003353	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1157951003354	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1157951003355	YGGT family; Region: YGGT; pfam02325
1157951003356	YGGT family; Region: YGGT; pfam02325
1157951003357	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1157951003358	active site
1157951003359	dimerization interface [polypeptide binding]; other site
1157951003360	HemN family oxidoreductase; Provisional; Region: PRK05660
1157951003361	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951003362	FeS/SAM binding site; other site
1157951003363	HemN C-terminal domain; Region: HemN_C; pfam06969
1157951003364	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1157951003365	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1157951003366	intersubunit interface [polypeptide binding]; other site
1157951003367	hypothetical protein; Provisional; Region: PRK10626
1157951003368	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1157951003369	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1157951003370	glutaminase; Provisional; Region: PRK00971
1157951003371	hypothetical protein; Provisional; Region: PRK11702
1157951003372	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951003373	S-adenosylmethionine binding site [chemical binding]; other site
1157951003374	adenine DNA glycosylase; Provisional; Region: PRK10880
1157951003375	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1157951003376	minor groove reading motif; other site
1157951003377	helix-hairpin-helix signature motif; other site
1157951003378	substrate binding pocket [chemical binding]; other site
1157951003379	active site
1157951003380	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1157951003381	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1157951003382	DNA binding and oxoG recognition site [nucleotide binding]
1157951003383	oxidative damage protection protein; Provisional; Region: PRK05408
1157951003384	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1157951003385	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1157951003386	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1157951003387	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1157951003388	catalytic residue [active]
1157951003389	integrase; Provisional; Region: PRK09692
1157951003390	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1157951003391	active site
1157951003392	Int/Topo IB signature motif; other site
1157951003393	Antirestriction protein (ArdA); Region: ArdA; pfam07275
1157951003394	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1157951003395	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1157951003396	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1157951003397	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
1157951003398	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1157951003399	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1157951003400	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1157951003401	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1157951003402	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1157951003403	UDP-glucose 4-epimerase; Region: PLN02240
1157951003404	NAD binding site [chemical binding]; other site
1157951003405	homodimer interface [polypeptide binding]; other site
1157951003406	active site
1157951003407	substrate binding site [chemical binding]; other site
1157951003408	tyrosine kinase; Provisional; Region: PRK11519
1157951003409	Chain length determinant protein; Region: Wzz; pfam02706
1157951003410	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1157951003411	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1157951003412	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1157951003413	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1157951003414	active site
1157951003415	polysaccharide export protein Wza; Provisional; Region: PRK15078
1157951003416	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1157951003417	SLBB domain; Region: SLBB; pfam10531
1157951003418	SLBB domain; Region: SLBB; pfam10531
1157951003419	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1157951003420	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1157951003421	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1157951003422	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1157951003423	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1157951003424	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
1157951003425	active site
1157951003426	substrate binding site [chemical binding]; other site
1157951003427	metal binding site [ion binding]; metal-binding site
1157951003428	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1157951003429	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1157951003430	metal-binding site
1157951003431	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1157951003432	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1157951003433	Substrate binding site; other site
1157951003434	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1157951003435	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1157951003436	active site
1157951003437	GDP-Mannose binding site [chemical binding]; other site
1157951003438	dimer interface [polypeptide binding]; other site
1157951003439	modified nudix motif
1157951003440	metal binding site [ion binding]; metal-binding site
1157951003441	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1157951003442	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1157951003443	NADP binding site [chemical binding]; other site
1157951003444	active site
1157951003445	putative substrate binding site [chemical binding]; other site
1157951003446	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1157951003447	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1157951003448	NADP-binding site; other site
1157951003449	homotetramer interface [polypeptide binding]; other site
1157951003450	substrate binding site [chemical binding]; other site
1157951003451	homodimer interface [polypeptide binding]; other site
1157951003452	active site
1157951003453	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1157951003454	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1157951003455	active site
1157951003456	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1157951003457	This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis; Region: GT1_wcfI_like; cd03825
1157951003458	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1157951003459	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1157951003460	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1157951003461	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
1157951003462	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1157951003463	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1157951003464	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1157951003465	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1157951003466	Predicted GTPase [General function prediction only]; Region: COG3596
1157951003467	YfjP GTPase; Region: YfjP; cd11383
1157951003468	G1 box; other site
1157951003469	GTP/Mg2+ binding site [chemical binding]; other site
1157951003470	Switch I region; other site
1157951003471	G2 box; other site
1157951003472	Switch II region; other site
1157951003473	G3 box; other site
1157951003474	G4 box; other site
1157951003475	G5 box; other site
1157951003476	Antirestriction protein; Region: Antirestrict; pfam03230
1157951003477	Antirestriction protein; Region: Antirestrict; pfam03230
1157951003478	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1157951003479	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1157951003480	MPN+ (JAMM) motif; other site
1157951003481	Zinc-binding site [ion binding]; other site
1157951003482	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1157951003483	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951003484	DNA binding site [nucleotide binding]
1157951003485	active site
1157951003486	Int/Topo IB signature motif; other site
1157951003487	PAAR motif; Region: PAAR_motif; pfam05488
1157951003488	Protein of unknown function (DUF3969); Region: DUF3969; pfam13108
1157951003489	S-type Pyocin; Region: Pyocin_S; pfam06958
1157951003490	Domain of unknown function (DUF4123); Region: DUF4123; pfam13503
1157951003491	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1157951003492	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1157951003493	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1157951003494	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733
1157951003495	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1157951003496	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1157951003497	putative active site [active]
1157951003498	catalytic site [active]
1157951003499	putative metal binding site [ion binding]; other site
1157951003500	heme exporter protein CcmB; Region: ccmB; TIGR01190
1157951003501	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1157951003502	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
1157951003503	Walker A/P-loop; other site
1157951003504	ATP binding site [chemical binding]; other site
1157951003505	Q-loop/lid; other site
1157951003506	ABC transporter signature motif; other site
1157951003507	Walker B; other site
1157951003508	D-loop; other site
1157951003509	H-loop/switch region; other site
1157951003510	Ion channel; Region: Ion_trans_2; pfam07885
1157951003511	TrkA-N domain; Region: TrkA_N; pfam02254
1157951003512	hypothetical protein; Provisional; Region: PRK10649
1157951003513	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1157951003514	Sulfatase; Region: Sulfatase; pfam00884
1157951003515	Predicted membrane protein [Function unknown]; Region: COG2323
1157951003516	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1157951003517	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496
1157951003518	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951003519	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1157951003520	Coenzyme A binding pocket [chemical binding]; other site
1157951003521	hypothetical protein; Provisional; Region: PRK11019
1157951003522	BCCT family transporter; Region: BCCT; cl00569
1157951003523	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1157951003524	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1157951003525	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1157951003526	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
1157951003527	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1157951003528	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1157951003529	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1157951003530	NAD binding site [chemical binding]; other site
1157951003531	catalytic residues [active]
1157951003532	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1157951003533	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1157951003534	putative active site [active]
1157951003535	putative metal binding site [ion binding]; other site
1157951003536	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1157951003537	putative substrate binding pocket [chemical binding]; other site
1157951003538	trimer interface [polypeptide binding]; other site
1157951003539	succinic semialdehyde dehydrogenase; Region: PLN02278
1157951003540	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1157951003541	tetramerization interface [polypeptide binding]; other site
1157951003542	NAD(P) binding site [chemical binding]; other site
1157951003543	catalytic residues [active]
1157951003544	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1157951003545	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Region: HpaI; TIGR02311
1157951003546	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1157951003547	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951003548	putative substrate translocation pore; other site
1157951003549	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1157951003550	Cupin domain; Region: Cupin_2; pfam07883
1157951003551	Cupin; Region: Cupin_6; pfam12852
1157951003552	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951003553	cellulose synthase catalytic subunit (UDP-forming); Region: CelA; TIGR03030
1157951003554	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1157951003555	DXD motif; other site
1157951003556	PilZ domain; Region: PilZ; pfam07238
1157951003557	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
1157951003558	TPR repeat; Region: TPR_11; pfam13414
1157951003559	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
1157951003560	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1157951003561	TPR motif; other site
1157951003562	binding surface
1157951003563	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1157951003564	binding surface
1157951003565	TPR motif; other site
1157951003566	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1157951003567	Cellulose synthase subunit D; Region: Cellsynth_D; pfam03500
1157951003568	PAS domain; Region: PAS_9; pfam13426
1157951003569	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1157951003570	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1157951003571	metal binding site [ion binding]; metal-binding site
1157951003572	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1157951003573	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1157951003574	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1157951003575	active site
1157951003576	tetramer interface; other site
1157951003577	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951003578	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951003579	dimerization interface [polypeptide binding]; other site
1157951003580	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1157951003581	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1157951003582	4-hydroxyphenylacetate 3-monooxygenase, reductase component; Region: HpaC; TIGR02296
1157951003583	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1157951003584	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1157951003585	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1157951003586	siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718
1157951003587	muropeptide transporter; Validated; Region: ampG; cl17669
1157951003588	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
1157951003589	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773
1157951003590	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951003591	N-terminal plug; other site
1157951003592	ligand-binding site [chemical binding]; other site
1157951003593	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1157951003594	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951003595	putative cyanate transporter; Provisional; Region: cynX; PRK09705
1157951003596	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951003597	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1157951003598	nucleoside/Zn binding site; other site
1157951003599	dimer interface [polypeptide binding]; other site
1157951003600	catalytic motif [active]
1157951003601	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1157951003602	Ankyrin repeat; Region: Ank; pfam00023
1157951003603	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1157951003604	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1157951003605	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1157951003606	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951003607	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951003608	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951003609	dimerization interface [polypeptide binding]; other site
1157951003610	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4994
1157951003611	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1157951003612	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1157951003613	active site
1157951003614	intersubunit interface [polypeptide binding]; other site
1157951003615	zinc binding site [ion binding]; other site
1157951003616	Na+ binding site [ion binding]; other site
1157951003617	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1157951003618	Phosphoglycerate kinase; Region: PGK; pfam00162
1157951003619	substrate binding site [chemical binding]; other site
1157951003620	hinge regions; other site
1157951003621	ADP binding site [chemical binding]; other site
1157951003622	catalytic site [active]
1157951003623	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1157951003624	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1157951003625	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1157951003626	transketolase; Reviewed; Region: PRK12753
1157951003627	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1157951003628	TPP-binding site [chemical binding]; other site
1157951003629	dimer interface [polypeptide binding]; other site
1157951003630	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1157951003631	PYR/PP interface [polypeptide binding]; other site
1157951003632	dimer interface [polypeptide binding]; other site
1157951003633	TPP binding site [chemical binding]; other site
1157951003634	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1157951003635	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
1157951003636	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951003637	Fimbrial protein; Region: Fimbrial; pfam00419
1157951003638	Fimbrial protein; Region: Fimbrial; pfam00419
1157951003639	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951003640	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
1157951003641	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951003642	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951003643	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1157951003644	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951003645	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951003646	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951003647	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951003648	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951003649	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951003650	non-specific DNA binding site [nucleotide binding]; other site
1157951003651	salt bridge; other site
1157951003652	sequence-specific DNA binding site [nucleotide binding]; other site
1157951003653	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1157951003654	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1157951003655	active site
1157951003656	catalytic site [active]
1157951003657	substrate binding site [chemical binding]; other site
1157951003658	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1157951003659	RNA/DNA hybrid binding site [nucleotide binding]; other site
1157951003660	active site
1157951003661	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
1157951003662	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1157951003663	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1157951003664	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1157951003665	catalytic residue [active]
1157951003666	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1157951003667	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1157951003668	Hha toxicity attenuator; Provisional; Region: PRK10667
1157951003669	gene expression modulator; Provisional; Region: PRK10945
1157951003670	Type III secretion system lipoprotein chaperone (YscW); Region: YscW; cl15825
1157951003671	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1157951003672	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1157951003673	active site
1157951003674	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1157951003675	catalytic triad [active]
1157951003676	dimer interface [polypeptide binding]; other site
1157951003677	Ammonium Transporter Family; Region: Ammonium_transp; cl03012
1157951003678	Nitrogen regulatory protein P-II; Region: P-II; pfam00543
1157951003679	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1157951003680	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1157951003681	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951003682	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1157951003683	Walker A/P-loop; other site
1157951003684	ATP binding site [chemical binding]; other site
1157951003685	Q-loop/lid; other site
1157951003686	ABC transporter signature motif; other site
1157951003687	Walker B; other site
1157951003688	D-loop; other site
1157951003689	H-loop/switch region; other site
1157951003690	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951003691	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1157951003692	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951003693	Walker A/P-loop; other site
1157951003694	ATP binding site [chemical binding]; other site
1157951003695	Q-loop/lid; other site
1157951003696	ABC transporter signature motif; other site
1157951003697	Walker B; other site
1157951003698	D-loop; other site
1157951003699	H-loop/switch region; other site
1157951003700	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1157951003701	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1157951003702	putative DNA binding site [nucleotide binding]; other site
1157951003703	putative Zn2+ binding site [ion binding]; other site
1157951003704	AsnC family; Region: AsnC_trans_reg; pfam01037
1157951003705	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1157951003706	Ligand Binding Site [chemical binding]; other site
1157951003707	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1157951003708	active site
1157951003709	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1157951003710	periplasmic folding chaperone; Provisional; Region: PRK10788
1157951003711	SurA N-terminal domain; Region: SurA_N_3; cl07813
1157951003712	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1157951003713	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1157951003714	IHF dimer interface [polypeptide binding]; other site
1157951003715	IHF - DNA interface [nucleotide binding]; other site
1157951003716	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1157951003717	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1157951003718	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1157951003719	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951003720	Walker A motif; other site
1157951003721	ATP binding site [chemical binding]; other site
1157951003722	Walker B motif; other site
1157951003723	arginine finger; other site
1157951003724	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1157951003725	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1157951003726	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1157951003727	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951003728	Walker A motif; other site
1157951003729	ATP binding site [chemical binding]; other site
1157951003730	Walker B motif; other site
1157951003731	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1157951003732	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1157951003733	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1157951003734	oligomer interface [polypeptide binding]; other site
1157951003735	active site residues [active]
1157951003736	trigger factor; Provisional; Region: tig; PRK01490
1157951003737	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1157951003738	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1157951003739	BolA-like protein; Region: BolA; cl00386
1157951003740	hypothetical protein; Provisional; Region: PRK11627
1157951003741	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1157951003742	Acetyl-coenzyme A transporter 1; Region: Acatn; pfam13000
1157951003743	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1157951003744	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951003745	putative substrate translocation pore; other site
1157951003746	hypothetical protein; Provisional; Region: PRK11528
1157951003747	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1157951003748	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1157951003749	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1157951003750	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1157951003751	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1157951003752	D-pathway; other site
1157951003753	Putative ubiquinol binding site [chemical binding]; other site
1157951003754	Low-spin heme (heme b) binding site [chemical binding]; other site
1157951003755	Putative water exit pathway; other site
1157951003756	Binuclear center (heme o3/CuB) [ion binding]; other site
1157951003757	K-pathway; other site
1157951003758	Putative proton exit pathway; other site
1157951003759	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1157951003760	Subunit I/III interface [polypeptide binding]; other site
1157951003761	Subunit III/IV interface [polypeptide binding]; other site
1157951003762	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1157951003763	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1157951003764	UbiA prenyltransferase family; Region: UbiA; pfam01040
1157951003765	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951003766	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951003767	putative substrate translocation pore; other site
1157951003768	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1157951003769	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1157951003770	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1157951003771	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1157951003772	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1157951003773	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1157951003774	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1157951003775	conserved cys residue [active]
1157951003776	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1157951003777	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1157951003778	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1157951003779	Ligand Binding Site [chemical binding]; other site
1157951003780	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1157951003781	active site residue [active]
1157951003782	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1157951003783	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1157951003784	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1157951003785	substrate binding pocket [chemical binding]; other site
1157951003786	chain length determination region; other site
1157951003787	substrate-Mg2+ binding site; other site
1157951003788	catalytic residues [active]
1157951003789	aspartate-rich region 1; other site
1157951003790	active site lid residues [active]
1157951003791	aspartate-rich region 2; other site
1157951003792	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1157951003793	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1157951003794	TPP-binding site; other site
1157951003795	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1157951003796	PYR/PP interface [polypeptide binding]; other site
1157951003797	dimer interface [polypeptide binding]; other site
1157951003798	TPP binding site [chemical binding]; other site
1157951003799	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1157951003800	thiamine monophosphate kinase; Provisional; Region: PRK05731
1157951003801	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1157951003802	ATP binding site [chemical binding]; other site
1157951003803	dimerization interface [polypeptide binding]; other site
1157951003804	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1157951003805	putative RNA binding site [nucleotide binding]; other site
1157951003806	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1157951003807	homopentamer interface [polypeptide binding]; other site
1157951003808	active site
1157951003809	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1157951003810	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1157951003811	catalytic motif [active]
1157951003812	Zn binding site [ion binding]; other site
1157951003813	RibD C-terminal domain; Region: RibD_C; cl17279
1157951003814	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1157951003815	ATP cone domain; Region: ATP-cone; pfam03477
1157951003816	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1157951003817	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1157951003818	Protein export membrane protein; Region: SecD_SecF; pfam02355
1157951003819	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1157951003820	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1157951003821	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1157951003822	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1157951003823	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1157951003824	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1157951003825	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1157951003826	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1157951003827	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1157951003828	Protein of unknown function, DUF479; Region: DUF479; cl01203
1157951003829	peroxidase; Provisional; Region: PRK15000
1157951003830	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1157951003831	dimer interface [polypeptide binding]; other site
1157951003832	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1157951003833	catalytic triad [active]
1157951003834	peroxidatic and resolving cysteines [active]
1157951003835	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1157951003836	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1157951003837	pyruvate dehydrogenase; Provisional; Region: PRK09124
1157951003838	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1157951003839	PYR/PP interface [polypeptide binding]; other site
1157951003840	dimer interface [polypeptide binding]; other site
1157951003841	tetramer interface [polypeptide binding]; other site
1157951003842	TPP binding site [chemical binding]; other site
1157951003843	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951003844	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1157951003845	TPP-binding site [chemical binding]; other site
1157951003846	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
1157951003847	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1157951003848	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1157951003849	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1157951003850	putative active site [active]
1157951003851	heme pocket [chemical binding]; other site
1157951003852	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951003853	dimer interface [polypeptide binding]; other site
1157951003854	phosphorylation site [posttranslational modification]
1157951003855	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951003856	ATP binding site [chemical binding]; other site
1157951003857	Mg2+ binding site [ion binding]; other site
1157951003858	G-X-G motif; other site
1157951003859	transcriptional regulator PhoB; Provisional; Region: PRK10161
1157951003860	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951003861	active site
1157951003862	phosphorylation site [posttranslational modification]
1157951003863	intermolecular recognition site; other site
1157951003864	dimerization interface [polypeptide binding]; other site
1157951003865	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951003866	DNA binding site [nucleotide binding]
1157951003867	exonuclease subunit SbcD; Provisional; Region: PRK10966
1157951003868	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1157951003869	active site
1157951003870	metal binding site [ion binding]; metal-binding site
1157951003871	DNA binding site [nucleotide binding]
1157951003872	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1157951003873	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951003874	AAA domain; Region: AAA_23; pfam13476
1157951003875	Walker A/P-loop; other site
1157951003876	ATP binding site [chemical binding]; other site
1157951003877	Q-loop/lid; other site
1157951003878	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951003879	ABC transporter signature motif; other site
1157951003880	Walker B; other site
1157951003881	D-loop; other site
1157951003882	H-loop/switch region; other site
1157951003883	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
1157951003884	dimer interface [polypeptide binding]; other site
1157951003885	FMN binding site [chemical binding]; other site
1157951003886	Fimbrial protein; Region: Fimbrial; pfam00419
1157951003887	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951003888	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951003889	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951003890	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951003891	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951003892	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951003893	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951003894	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951003895	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951003896	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951003897	non-specific DNA binding site [nucleotide binding]; other site
1157951003898	salt bridge; other site
1157951003899	sequence-specific DNA binding site [nucleotide binding]; other site
1157951003900	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1157951003901	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1157951003902	active site
1157951003903	metal binding site [ion binding]; metal-binding site
1157951003904	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1157951003905	fructokinase; Reviewed; Region: PRK09557
1157951003906	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1157951003907	nucleotide binding site [chemical binding]; other site
1157951003908	recombination associated protein; Reviewed; Region: rdgC; PRK00321
1157951003909	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951003910	Coenzyme A binding pocket [chemical binding]; other site
1157951003911	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1157951003912	CPxP  motif; other site
1157951003913	putative inner membrane protein; Provisional; Region: PRK11099
1157951003914	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
1157951003915	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1157951003916	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1157951003917	cystathionine beta-lyase; Provisional; Region: PRK08114
1157951003918	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1157951003919	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951003920	catalytic residue [active]
1157951003921	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1157951003922	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1157951003923	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
1157951003924	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1157951003925	DNA binding residues [nucleotide binding]
1157951003926	dimer interface [polypeptide binding]; other site
1157951003927	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1157951003928	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1157951003929	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1157951003930	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1157951003931	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1157951003932	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1157951003933	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1157951003934	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1157951003935	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1157951003936	IMP binding site; other site
1157951003937	dimer interface [polypeptide binding]; other site
1157951003938	interdomain contacts; other site
1157951003939	partial ornithine binding site; other site
1157951003940	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1157951003941	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1157951003942	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1157951003943	catalytic site [active]
1157951003944	subunit interface [polypeptide binding]; other site
1157951003945	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1157951003946	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1157951003947	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1157951003948	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
1157951003949	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1157951003950	substrate binding site [chemical binding]; other site
1157951003951	activation loop (A-loop); other site
1157951003952	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1157951003953	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1157951003954	metal ion-dependent adhesion site (MIDAS); other site
1157951003955	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1157951003956	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1157951003957	metal ion-dependent adhesion site (MIDAS); other site
1157951003958	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1157951003959	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1157951003960	putative metal binding site [ion binding]; other site
1157951003961	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1157951003962	metal ion-dependent adhesion site (MIDAS); other site
1157951003963	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1157951003964	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1157951003965	Protein of unknown function (DUF2983); Region: DUF2983; pfam11202
1157951003966	probable sucrose-phosphatase; Region: PLN02382
1157951003967	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951003968	active site
1157951003969	Protein of unknown function (DUF3706); Region: DUF3706; pfam12500
1157951003970	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1157951003971	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1157951003972	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1157951003973	putative metal binding site [ion binding]; other site
1157951003974	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1157951003975	putative metal binding site [ion binding]; other site
1157951003976	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1157951003977	Uncharacterized protein involved in stress response [General function prediction only]; Region: COG4110
1157951003978	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1157951003979	putative metal binding site [ion binding]; other site
1157951003980	tellurite resistance protein terB; Region: terB; cd07176
1157951003981	putative metal binding site [ion binding]; other site
1157951003982	Integral membrane protein TerC family; Region: TerC; cl10468
1157951003983	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1157951003984	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1157951003985	putative metal binding site [ion binding]; other site
1157951003986	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1157951003987	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1157951003988	putative metal binding site [ion binding]; other site
1157951003989	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1157951003990	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1157951003991	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1157951003992	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1157951003993	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1157951003994	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1157951003995	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1157951003996	lipoprotein signal peptidase; Provisional; Region: PRK14787
1157951003997	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1157951003998	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1157951003999	active site
1157951004000	HIGH motif; other site
1157951004001	nucleotide binding site [chemical binding]; other site
1157951004002	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1157951004003	active site
1157951004004	KMSKS motif; other site
1157951004005	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1157951004006	tRNA binding surface [nucleotide binding]; other site
1157951004007	anticodon binding site; other site
1157951004008	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1157951004009	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1157951004010	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1157951004011	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1157951004012	active site
1157951004013	Riboflavin kinase; Region: Flavokinase; smart00904
1157951004014	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1157951004015	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1157951004016	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951004017	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1157951004018	putative dimerization interface [polypeptide binding]; other site
1157951004019	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1157951004020	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1157951004021	EamA-like transporter family; Region: EamA; pfam00892
1157951004022	chaperone protein DnaJ; Provisional; Region: PRK10767
1157951004023	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1157951004024	HSP70 interaction site [polypeptide binding]; other site
1157951004025	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1157951004026	substrate binding site [polypeptide binding]; other site
1157951004027	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1157951004028	Zn binding sites [ion binding]; other site
1157951004029	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1157951004030	dimer interface [polypeptide binding]; other site
1157951004031	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1157951004032	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1157951004033	nucleotide binding site [chemical binding]; other site
1157951004034	hypothetical protein; Provisional; Region: PRK10659
1157951004035	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1157951004036	MPT binding site; other site
1157951004037	trimer interface [polypeptide binding]; other site
1157951004038	transaldolase-like protein; Provisional; Region: PTZ00411
1157951004039	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1157951004040	active site
1157951004041	dimer interface [polypeptide binding]; other site
1157951004042	catalytic residue [active]
1157951004043	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1157951004044	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1157951004045	active site
1157951004046	catalytic tetrad [active]
1157951004047	threonine synthase; Validated; Region: PRK09225
1157951004048	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1157951004049	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951004050	catalytic residue [active]
1157951004051	homoserine kinase; Provisional; Region: PRK01212
1157951004052	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1157951004053	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1157951004054	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1157951004055	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1157951004056	putative catalytic residues [active]
1157951004057	putative nucleotide binding site [chemical binding]; other site
1157951004058	putative aspartate binding site [chemical binding]; other site
1157951004059	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1157951004060	dimer interface [polypeptide binding]; other site
1157951004061	putative threonine allosteric regulatory site; other site
1157951004062	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1157951004063	putative threonine allosteric regulatory site; other site
1157951004064	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1157951004065	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1157951004066	two-component response regulator; Provisional; Region: PRK11173
1157951004067	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951004068	active site
1157951004069	phosphorylation site [posttranslational modification]
1157951004070	intermolecular recognition site; other site
1157951004071	dimerization interface [polypeptide binding]; other site
1157951004072	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951004073	DNA binding site [nucleotide binding]
1157951004074	hypothetical protein; Provisional; Region: PRK10756
1157951004075	CreA protein; Region: CreA; pfam05981
1157951004076	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1157951004077	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951004078	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1157951004079	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1157951004080	catalytic core [active]
1157951004081	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1157951004082	Trp operon repressor; Provisional; Region: PRK01381
1157951004083	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1157951004084	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1157951004085	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1157951004086	catalytic residue [active]
1157951004087	lytic murein transglycosylase; Provisional; Region: PRK11619
1157951004088	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1157951004089	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1157951004090	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951004091	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951004092	ABC transporter; Region: ABC_tran_2; pfam12848
1157951004093	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951004094	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951004095	non-specific DNA binding site [nucleotide binding]; other site
1157951004096	salt bridge; other site
1157951004097	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1157951004098	sequence-specific DNA binding site [nucleotide binding]; other site
1157951004099	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1157951004100	active site
1157951004101	nucleotide binding site [chemical binding]; other site
1157951004102	HIGH motif; other site
1157951004103	KMSKS motif; other site
1157951004104	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1157951004105	DNA repair protein RadA; Provisional; Region: PRK11823
1157951004106	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1157951004107	Walker A motif/ATP binding site; other site
1157951004108	ATP binding site [chemical binding]; other site
1157951004109	Walker B motif; other site
1157951004110	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1157951004111	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1157951004112	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951004113	motif II; other site
1157951004114	Bacterial virulence factor haemolysin; Region: SMP_2; cl11479
1157951004115	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1157951004116	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1157951004117	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1157951004118	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1157951004119	DNA binding residues [nucleotide binding]
1157951004120	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
1157951004121	FecR protein; Region: FecR; pfam04773
1157951004122	Secretin and TonB N terminus short domain; Region: STN; smart00965
1157951004123	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1157951004124	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
1157951004125	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
1157951004126	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1157951004127	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
1157951004128	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1157951004129	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1157951004130	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1157951004131	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1157951004132	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1157951004133	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1157951004134	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951004135	Coenzyme A binding pocket [chemical binding]; other site
1157951004136	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1157951004137	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1157951004138	phosphopentomutase; Provisional; Region: PRK05362
1157951004139	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1157951004140	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1157951004141	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1157951004142	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1157951004143	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1157951004144	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1157951004145	intersubunit interface [polypeptide binding]; other site
1157951004146	active site
1157951004147	catalytic residue [active]
1157951004148	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1157951004149	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1157951004150	Nucleoside recognition; Region: Gate; pfam07670
1157951004151	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1157951004152	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1157951004153	active site
1157951004154	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1157951004155	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1157951004156	active site
1157951004157	nucleophile elbow; other site
1157951004158	periplasmic protein; Provisional; Region: PRK10568
1157951004159	BON domain; Region: BON; pfam04972
1157951004160	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1157951004161	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1157951004162	G1 box; other site
1157951004163	putative GEF interaction site [polypeptide binding]; other site
1157951004164	GTP/Mg2+ binding site [chemical binding]; other site
1157951004165	Switch I region; other site
1157951004166	G2 box; other site
1157951004167	G3 box; other site
1157951004168	Switch II region; other site
1157951004169	G4 box; other site
1157951004170	G5 box; other site
1157951004171	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1157951004172	tartrate dehydrogenase; Region: TTC; TIGR02089
1157951004173	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1157951004174	transcriptional activator TtdR; Provisional; Region: PRK09801
1157951004175	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951004176	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951004177	dimerization interface [polypeptide binding]; other site
1157951004178	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951004179	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951004180	non-specific DNA binding site [nucleotide binding]; other site
1157951004181	salt bridge; other site
1157951004182	sequence-specific DNA binding site [nucleotide binding]; other site
1157951004183	PAS fold; Region: PAS_3; pfam08447
1157951004184	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
1157951004185	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
1157951004186	FMN-binding pocket [chemical binding]; other site
1157951004187	flavin binding motif; other site
1157951004188	phosphate binding motif [ion binding]; other site
1157951004189	beta-alpha-beta structure motif; other site
1157951004190	NAD binding pocket [chemical binding]; other site
1157951004191	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1157951004192	catalytic loop [active]
1157951004193	iron binding site [ion binding]; other site
1157951004194	succinic semialdehyde dehydrogenase; Region: PLN02278
1157951004195	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1157951004196	tetramerization interface [polypeptide binding]; other site
1157951004197	NAD(P) binding site [chemical binding]; other site
1157951004198	catalytic residues [active]
1157951004199	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1157951004200	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1157951004201	[2Fe-2S] cluster binding site [ion binding]; other site
1157951004202	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
1157951004203	putative alpha subunit interface [polypeptide binding]; other site
1157951004204	putative active site [active]
1157951004205	putative substrate binding site [chemical binding]; other site
1157951004206	Fe binding site [ion binding]; other site
1157951004207	BCCT family transporter; Region: BCCT; pfam02028
1157951004208	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1157951004209	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951004210	Coenzyme A binding pocket [chemical binding]; other site
1157951004211	DNA polymerase III subunit psi; Validated; Region: PRK06856
1157951004212	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1157951004213	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1157951004214	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951004215	S-adenosylmethionine binding site [chemical binding]; other site
1157951004216	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1157951004217	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951004218	Coenzyme A binding pocket [chemical binding]; other site
1157951004219	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1157951004220	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1157951004221	PhoU domain; Region: PhoU; pfam01895
1157951004222	alkaline phosphatase; Provisional; Region: PRK10518
1157951004223	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1157951004224	active site
1157951004225	dimer interface [polypeptide binding]; other site
1157951004226	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1157951004227	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1157951004228	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1157951004229	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
1157951004230	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1157951004231	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1157951004232	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1157951004233	DNA binding residues [nucleotide binding]
1157951004234	dimerization interface [polypeptide binding]; other site
1157951004235	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1157951004236	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1157951004237	amidase catalytic site [active]
1157951004238	Zn binding residues [ion binding]; other site
1157951004239	substrate binding site [chemical binding]; other site
1157951004240	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1157951004241	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1157951004242	FAD binding site [chemical binding]; other site
1157951004243	Fimbrial protein; Region: Fimbrial; pfam00419
1157951004244	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951004245	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1157951004246	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951004247	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951004248	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1157951004249	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951004250	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951004251	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951004252	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951004253	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951004254	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951004255	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951004256	non-specific DNA binding site [nucleotide binding]; other site
1157951004257	salt bridge; other site
1157951004258	sequence-specific DNA binding site [nucleotide binding]; other site
1157951004259	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1157951004260	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1157951004261	NAD(P) binding site [chemical binding]; other site
1157951004262	catalytic residues [active]
1157951004263	Protein of unknown function (DUF861); Region: Cupin_3; cl17594
1157951004264	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1157951004265	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1157951004266	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1157951004267	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1157951004268	DNA binding residues [nucleotide binding]
1157951004269	dimerization interface [polypeptide binding]; other site
1157951004270	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1157951004271	active site
1157951004272	tetramer interface [polypeptide binding]; other site
1157951004273	putative glycosyl transferase; Provisional; Region: PRK10073
1157951004274	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1157951004275	active site
1157951004276	Protein of unknown function (DUF808); Region: DUF808; pfam05661
1157951004277	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1157951004278	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1157951004279	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1157951004280	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1157951004281	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1157951004282	[4Fe-4S] binding site [ion binding]; other site
1157951004283	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951004284	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951004285	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951004286	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1157951004287	molybdopterin cofactor binding site; other site
1157951004288	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1157951004289	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1157951004290	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1157951004291	HAMP domain; Region: HAMP; pfam00672
1157951004292	Histidine kinase; Region: HisKA_3; pfam07730
1157951004293	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951004294	ATP binding site [chemical binding]; other site
1157951004295	Mg2+ binding site [ion binding]; other site
1157951004296	G-X-G motif; other site
1157951004297	transcriptional regulator NarL; Provisional; Region: PRK10651
1157951004298	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951004299	active site
1157951004300	phosphorylation site [posttranslational modification]
1157951004301	intermolecular recognition site; other site
1157951004302	dimerization interface [polypeptide binding]; other site
1157951004303	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1157951004304	DNA binding residues [nucleotide binding]
1157951004305	dimerization interface [polypeptide binding]; other site
1157951004306	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1157951004307	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
1157951004308	active site
1157951004309	metal binding site [ion binding]; metal-binding site
1157951004310	nudix motif; other site
1157951004311	Flavodoxin domain; Region: Flavodoxin_5; cl17428
1157951004312	Cation transport protein; Region: TrkH; cl17365
1157951004313	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1157951004314	hypothetical protein; Provisional; Region: PRK11568
1157951004315	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1157951004316	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1157951004317	proline dipeptidase; Provisional; Region: PRK13607
1157951004318	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1157951004319	active site
1157951004320	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1157951004321	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1157951004322	substrate binding site [chemical binding]; other site
1157951004323	oxyanion hole (OAH) forming residues; other site
1157951004324	trimer interface [polypeptide binding]; other site
1157951004325	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1157951004326	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1157951004327	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1157951004328	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1157951004329	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1157951004330	dimer interface [polypeptide binding]; other site
1157951004331	active site
1157951004332	FMN reductase; Validated; Region: fre; PRK08051
1157951004333	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1157951004334	FAD binding pocket [chemical binding]; other site
1157951004335	FAD binding motif [chemical binding]; other site
1157951004336	phosphate binding motif [ion binding]; other site
1157951004337	beta-alpha-beta structure motif; other site
1157951004338	NAD binding pocket [chemical binding]; other site
1157951004339	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1157951004340	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1157951004341	active site pocket [active]
1157951004342	oxyanion hole [active]
1157951004343	catalytic triad [active]
1157951004344	active site nucleophile [active]
1157951004345	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1157951004346	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1157951004347	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1157951004348	sec-independent translocase; Provisional; Region: PRK01770
1157951004349	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1157951004350	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1157951004351	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1157951004352	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1157951004353	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1157951004354	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1157951004355	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951004356	S-adenosylmethionine binding site [chemical binding]; other site
1157951004357	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1157951004358	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
1157951004359	RmuC family; Region: RmuC; pfam02646
1157951004360	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1157951004361	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1157951004362	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
1157951004363	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
1157951004364	uridine phosphorylase; Provisional; Region: PRK11178
1157951004365	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1157951004366	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1157951004367	GntP family permease; Region: GntP_permease; pfam02447
1157951004368	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
1157951004369	putative NAD(P) binding site [chemical binding]; other site
1157951004370	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1157951004371	active site
1157951004372	putative substrate binding site [chemical binding]; other site
1157951004373	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1157951004374	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1157951004375	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1157951004376	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
1157951004377	putative aldolase; Validated; Region: PRK08130
1157951004378	intersubunit interface [polypeptide binding]; other site
1157951004379	active site
1157951004380	Zn2+ binding site [ion binding]; other site
1157951004381	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1157951004382	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1157951004383	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1157951004384	Bacterial protein of unknown function (DUF937); Region: DUF937; cl01528
1157951004385	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1157951004386	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1157951004387	THF binding site; other site
1157951004388	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1157951004389	substrate binding site [chemical binding]; other site
1157951004390	THF binding site; other site
1157951004391	zinc-binding site [ion binding]; other site
1157951004392	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1157951004393	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951004394	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1157951004395	putative dimerization interface [polypeptide binding]; other site
1157951004396	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1157951004397	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1157951004398	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1157951004399	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1157951004400	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
1157951004401	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1157951004402	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951004403	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951004404	putative substrate translocation pore; other site
1157951004405	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1157951004406	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951004407	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951004408	non-specific DNA binding site [nucleotide binding]; other site
1157951004409	salt bridge; other site
1157951004410	sequence-specific DNA binding site [nucleotide binding]; other site
1157951004411	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
1157951004412	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1157951004413	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1157951004414	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1157951004415	putative valine binding site [chemical binding]; other site
1157951004416	dimer interface [polypeptide binding]; other site
1157951004417	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1157951004418	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1157951004419	PYR/PP interface [polypeptide binding]; other site
1157951004420	dimer interface [polypeptide binding]; other site
1157951004421	TPP binding site [chemical binding]; other site
1157951004422	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951004423	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1157951004424	TPP-binding site [chemical binding]; other site
1157951004425	dimer interface [polypeptide binding]; other site
1157951004426	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951004427	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951004428	putative substrate translocation pore; other site
1157951004429	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951004430	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1157951004431	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951004432	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1157951004433	DNA protecting protein DprA; Region: dprA; TIGR00732
1157951004434	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1157951004435	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951004436	ATP binding site [chemical binding]; other site
1157951004437	putative Mg++ binding site [ion binding]; other site
1157951004438	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951004439	nucleotide binding region [chemical binding]; other site
1157951004440	ATP-binding site [chemical binding]; other site
1157951004441	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951004442	active site
1157951004443	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1157951004444	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1157951004445	dimer interface [polypeptide binding]; other site
1157951004446	ssDNA binding site [nucleotide binding]; other site
1157951004447	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1157951004448	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1157951004449	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1157951004450	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1157951004451	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1157951004452	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
1157951004453	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1157951004454	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1157951004455	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1157951004456	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1157951004457	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951004458	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951004459	homodimer interface [polypeptide binding]; other site
1157951004460	catalytic residue [active]
1157951004461	alanine racemase; Reviewed; Region: alr; PRK00053
1157951004462	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1157951004463	active site
1157951004464	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1157951004465	substrate binding site [chemical binding]; other site
1157951004466	catalytic residues [active]
1157951004467	dimer interface [polypeptide binding]; other site
1157951004468	replicative DNA helicase; Provisional; Region: PRK08006
1157951004469	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1157951004470	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1157951004471	Walker A motif; other site
1157951004472	ATP binding site [chemical binding]; other site
1157951004473	Walker B motif; other site
1157951004474	DNA binding loops [nucleotide binding]
1157951004475	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1157951004476	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1157951004477	NADP binding site [chemical binding]; other site
1157951004478	dimer interface [polypeptide binding]; other site
1157951004479	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1157951004480	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1157951004481	FMN binding site [chemical binding]; other site
1157951004482	active site
1157951004483	catalytic residues [active]
1157951004484	substrate binding site [chemical binding]; other site
1157951004485	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1157951004486	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1157951004487	active site
1157951004488	Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011
1157951004489	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1157951004490	active site
1157951004491	tetramer interface [polypeptide binding]; other site
1157951004492	ornithine decarboxylase; Provisional; Region: PRK13578
1157951004493	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1157951004494	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1157951004495	homodimer interface [polypeptide binding]; other site
1157951004496	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951004497	catalytic residue [active]
1157951004498	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1157951004499	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1157951004500	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1157951004501	Protein of unknown function (DUF2750); Region: DUF2750; pfam11042
1157951004502	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1157951004503	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1157951004504	substrate binding site [chemical binding]; other site
1157951004505	dimer interface [polypeptide binding]; other site
1157951004506	ATP binding site [chemical binding]; other site
1157951004507	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1157951004508	intersubunit interface [polypeptide binding]; other site
1157951004509	active site
1157951004510	catalytic residue [active]
1157951004511	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1157951004512	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1157951004513	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1157951004514	ribonuclease Z; Region: RNase_Z; TIGR02651
1157951004515	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1157951004516	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1157951004517	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951004518	Walker A motif; other site
1157951004519	ATP binding site [chemical binding]; other site
1157951004520	Walker B motif; other site
1157951004521	arginine finger; other site
1157951004522	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1157951004523	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1157951004524	hypothetical protein; Reviewed; Region: PRK09588
1157951004525	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1157951004526	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
1157951004527	HTH domain; Region: HTH_11; pfam08279
1157951004528	Predicted transcriptional regulator [Transcription]; Region: COG2378
1157951004529	WYL domain; Region: WYL; pfam13280
1157951004530	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1157951004531	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1157951004532	putative C-terminal domain interface [polypeptide binding]; other site
1157951004533	putative GSH binding site (G-site) [chemical binding]; other site
1157951004534	putative dimer interface [polypeptide binding]; other site
1157951004535	C-terminal, alpha helical domain of an unknown subfamily 8 of Glutathione S-transferases; Region: GST_C_8; cd03207
1157951004536	dimer interface [polypeptide binding]; other site
1157951004537	N-terminal domain interface [polypeptide binding]; other site
1157951004538	putative substrate binding pocket (H-site) [chemical binding]; other site
1157951004539	DoxX; Region: DoxX; pfam07681
1157951004540	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
1157951004541	Helix-turn-helix domain; Region: HTH_18; pfam12833
1157951004542	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951004543	Molybdenum cofactor biosynthesis protein F; Region: MoaF; pfam10703
1157951004544	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
1157951004545	Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_1; cd09996
1157951004546	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
1157951004547	active site
1157951004548	Zn binding site [ion binding]; other site
1157951004549	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1157951004550	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1157951004551	active site
1157951004552	Molybdenum cofactor biosynthesis protein F; Region: MoaF; pfam10703
1157951004553	potential frameshift: common BLAST hit: gi|37520992|ref|NP_924369.1| oxidoreductase
1157951004554	outer membrane porin, OprD family; Region: OprD; pfam03573
1157951004555	Fimbrial protein; Region: Fimbrial; pfam00419
1157951004556	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951004557	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
1157951004558	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951004559	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951004560	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1157951004561	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951004562	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951004563	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951004564	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951004565	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951004566	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951004567	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951004568	non-specific DNA binding site [nucleotide binding]; other site
1157951004569	salt bridge; other site
1157951004570	sequence-specific DNA binding site [nucleotide binding]; other site
1157951004571	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1157951004572	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1157951004573	redox-sensitive transcriptional activator SoxR; Region: SoxR; TIGR01950
1157951004574	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1157951004575	DNA binding residues [nucleotide binding]
1157951004576	dimer interface [polypeptide binding]; other site
1157951004577	[2Fe-2S] cluster binding site [ion binding]; other site
1157951004578	Predicted membrane protein [Function unknown]; Region: COG2259
1157951004579	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1157951004580	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951004581	multidrug efflux protein; Reviewed; Region: PRK09579
1157951004582	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1157951004583	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1157951004584	O-acetylhomoserine aminocarboxypropyltransferase; Validated; Region: PRK06084
1157951004585	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1157951004586	homodimer interface [polypeptide binding]; other site
1157951004587	substrate-cofactor binding pocket; other site
1157951004588	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951004589	catalytic residue [active]
1157951004590	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1157951004591	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1157951004592	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1157951004593	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1157951004594	PAAR motif; Region: PAAR_motif; pfam05488
1157951004595	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1157951004596	Protein of unknown function (DUF4026); Region: DUF4026; pfam13218
1157951004597	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
1157951004598	Surface antigen; Region: Bac_surface_Ag; pfam01103
1157951004599	Protein of unknown function (DUF4056); Region: DUF4056; pfam13265
1157951004600	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
1157951004601	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1157951004602	SGNH_peri2; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri2; cd01829
1157951004603	active site
1157951004604	catalytic triad [active]
1157951004605	oxyanion hole [active]
1157951004606	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1157951004607	oxyanion hole [active]
1157951004608	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
1157951004609	active site
1157951004610	oxyanion hole [active]
1157951004611	catalytic triad [active]
1157951004612	low affinity gluconate transporter; Provisional; Region: PRK10472
1157951004613	gluconate transporter; Region: gntP; TIGR00791
1157951004614	Shikimate kinase; Region: SKI; pfam01202
1157951004615	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1157951004616	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1157951004617	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951004618	DNA binding site [nucleotide binding]
1157951004619	domain linker motif; other site
1157951004620	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1157951004621	putative ligand binding site [chemical binding]; other site
1157951004622	putative dimerization interface [polypeptide binding]; other site
1157951004623	Metal binding protein HemV-2.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: HemV-2; cd01147
1157951004624	putative metal binding site [ion binding]; other site
1157951004625	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1157951004626	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1157951004627	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951004628	ABC-ATPase subunit  interface; other site
1157951004629	dimer interface [polypeptide binding]; other site
1157951004630	putative PBP binding regions; other site
1157951004631	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1157951004632	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1157951004633	Walker A/P-loop; other site
1157951004634	ATP binding site [chemical binding]; other site
1157951004635	Q-loop/lid; other site
1157951004636	ABC transporter signature motif; other site
1157951004637	Walker B; other site
1157951004638	D-loop; other site
1157951004639	H-loop/switch region; other site
1157951004640	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951004641	S-adenosylmethionine binding site [chemical binding]; other site
1157951004642	molybdenum transport protein ModD; Provisional; Region: PRK06096
1157951004643	ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport. In general, QPRTases are part of the de novo synthesis pathway of NAD in both prokaryotes and...; Region: modD_like; cd01573
1157951004644	dimerization interface [polypeptide binding]; other site
1157951004645	active site
1157951004646	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1157951004647	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951004648	N-terminal plug; other site
1157951004649	ligand-binding site [chemical binding]; other site
1157951004650	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1157951004651	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1157951004652	DNA binding site [nucleotide binding]
1157951004653	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1157951004654	catalytic nucleophile [active]
1157951004655	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1157951004656	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951004657	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951004658	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951004659	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951004660	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951004661	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951004662	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951004663	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951004664	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951004665	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951004666	putative chaperone protein EcpD; Provisional; Region: PRK09926
1157951004667	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951004668	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951004669	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951004670	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1157951004671	metal binding site 2 [ion binding]; metal-binding site
1157951004672	putative DNA binding helix; other site
1157951004673	metal binding site 1 [ion binding]; metal-binding site
1157951004674	dimer interface [polypeptide binding]; other site
1157951004675	structural Zn2+ binding site [ion binding]; other site
1157951004676	LexA repressor; Validated; Region: PRK00215
1157951004677	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1157951004678	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1157951004679	Catalytic site [active]
1157951004680	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1157951004681	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1157951004682	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1157951004683	putative acyl-acceptor binding pocket; other site
1157951004684	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1157951004685	UbiA prenyltransferase family; Region: UbiA; pfam01040
1157951004686	Chorismate lyase; Region: Chor_lyase; cl01230
1157951004687	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1157951004688	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1157951004689	active site
1157951004690	dimer interface [polypeptide binding]; other site
1157951004691	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1157951004692	dimer interface [polypeptide binding]; other site
1157951004693	active site
1157951004694	aspartate kinase III; Validated; Region: PRK09084
1157951004695	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1157951004696	nucleotide binding site [chemical binding]; other site
1157951004697	substrate binding site [chemical binding]; other site
1157951004698	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1157951004699	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1157951004700	dimer interface [polypeptide binding]; other site
1157951004701	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1157951004702	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951004703	Sel1-like repeats; Region: SEL1; smart00671
1157951004704	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951004705	Sel1-like repeats; Region: SEL1; smart00671
1157951004706	Sel1-like repeats; Region: SEL1; smart00671
1157951004707	Sel1-like repeats; Region: SEL1; smart00671
1157951004708	Sel1-like repeats; Region: SEL1; smart00671
1157951004709	PsbP; Region: PsbP; cl03356
1157951004710	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1157951004711	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1157951004712	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1157951004713	substrate binding pocket [chemical binding]; other site
1157951004714	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1157951004715	B12 binding site [chemical binding]; other site
1157951004716	cobalt ligand [ion binding]; other site
1157951004717	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1157951004718	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1157951004719	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1157951004720	Bacterial transcriptional regulator; Region: IclR; pfam01614
1157951004721	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1157951004722	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1157951004723	amidase catalytic site [active]
1157951004724	Zn binding residues [ion binding]; other site
1157951004725	substrate binding site [chemical binding]; other site
1157951004726	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1157951004727	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951004728	non-specific DNA binding site [nucleotide binding]; other site
1157951004729	salt bridge; other site
1157951004730	sequence-specific DNA binding site [nucleotide binding]; other site
1157951004731	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
1157951004732	Dehydratase family; Region: ILVD_EDD; cl00340
1157951004733	phosphogluconate dehydratase; Validated; Region: PRK09054
1157951004734	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1157951004735	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1157951004736	active site
1157951004737	intersubunit interface [polypeptide binding]; other site
1157951004738	catalytic residue [active]
1157951004739	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1157951004740	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1157951004741	isocitrate lyase; Provisional; Region: PRK15063
1157951004742	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1157951004743	tetramer interface [polypeptide binding]; other site
1157951004744	active site
1157951004745	Mg2+/Mn2+ binding site [ion binding]; other site
1157951004746	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1157951004747	malate synthase A; Region: malate_syn_A; TIGR01344
1157951004748	active site
1157951004749	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1157951004750	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1157951004751	proposed active site lysine [active]
1157951004752	conserved cys residue [active]
1157951004753	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1157951004754	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1157951004755	purine monophosphate binding site [chemical binding]; other site
1157951004756	dimer interface [polypeptide binding]; other site
1157951004757	putative catalytic residues [active]
1157951004758	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1157951004759	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1157951004760	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1157951004761	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1157951004762	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1157951004763	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1157951004764	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1157951004765	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1157951004766	IHF dimer interface [polypeptide binding]; other site
1157951004767	IHF - DNA interface [nucleotide binding]; other site
1157951004768	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1157951004769	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1157951004770	Active_site [active]
1157951004771	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1157951004772	substrate binding site [chemical binding]; other site
1157951004773	active site
1157951004774	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1157951004775	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1157951004776	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1157951004777	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1157951004778	putative NADH binding site [chemical binding]; other site
1157951004779	putative active site [active]
1157951004780	nudix motif; other site
1157951004781	putative metal binding site [ion binding]; other site
1157951004782	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1157951004783	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1157951004784	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
1157951004785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951004786	dimer interface [polypeptide binding]; other site
1157951004787	conserved gate region; other site
1157951004788	putative PBP binding loops; other site
1157951004789	ABC-ATPase subunit interface; other site
1157951004790	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1157951004791	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951004792	dimer interface [polypeptide binding]; other site
1157951004793	conserved gate region; other site
1157951004794	putative PBP binding loops; other site
1157951004795	ABC-ATPase subunit interface; other site
1157951004796	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1157951004797	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951004798	Walker A/P-loop; other site
1157951004799	ATP binding site [chemical binding]; other site
1157951004800	Q-loop/lid; other site
1157951004801	ABC transporter signature motif; other site
1157951004802	Walker B; other site
1157951004803	D-loop; other site
1157951004804	H-loop/switch region; other site
1157951004805	TOBE domain; Region: TOBE_2; pfam08402
1157951004806	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1157951004807	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1157951004808	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1157951004809	ThiC-associated domain; Region: ThiC-associated; pfam13667
1157951004810	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1157951004811	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1157951004812	thiamine phosphate binding site [chemical binding]; other site
1157951004813	active site
1157951004814	pyrophosphate binding site [ion binding]; other site
1157951004815	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1157951004816	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1157951004817	ATP binding site [chemical binding]; other site
1157951004818	substrate interface [chemical binding]; other site
1157951004819	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1157951004820	thiS-thiF/thiG interaction site; other site
1157951004821	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1157951004822	ThiS interaction site; other site
1157951004823	putative active site [active]
1157951004824	tetramer interface [polypeptide binding]; other site
1157951004825	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1157951004826	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951004827	FeS/SAM binding site; other site
1157951004828	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1157951004829	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1157951004830	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1157951004831	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1157951004832	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1157951004833	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1157951004834	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1157951004835	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1157951004836	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1157951004837	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1157951004838	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1157951004839	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1157951004840	DNA binding site [nucleotide binding]
1157951004841	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1157951004842	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1157951004843	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1157951004844	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1157951004845	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1157951004846	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1157951004847	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1157951004848	RPB3 interaction site [polypeptide binding]; other site
1157951004849	RPB1 interaction site [polypeptide binding]; other site
1157951004850	RPB11 interaction site [polypeptide binding]; other site
1157951004851	RPB10 interaction site [polypeptide binding]; other site
1157951004852	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1157951004853	core dimer interface [polypeptide binding]; other site
1157951004854	peripheral dimer interface [polypeptide binding]; other site
1157951004855	L10 interface [polypeptide binding]; other site
1157951004856	L11 interface [polypeptide binding]; other site
1157951004857	putative EF-Tu interaction site [polypeptide binding]; other site
1157951004858	putative EF-G interaction site [polypeptide binding]; other site
1157951004859	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1157951004860	23S rRNA interface [nucleotide binding]; other site
1157951004861	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1157951004862	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1157951004863	mRNA/rRNA interface [nucleotide binding]; other site
1157951004864	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1157951004865	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1157951004866	23S rRNA interface [nucleotide binding]; other site
1157951004867	L7/L12 interface [polypeptide binding]; other site
1157951004868	putative thiostrepton binding site; other site
1157951004869	L25 interface [polypeptide binding]; other site
1157951004870	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1157951004871	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1157951004872	putative homodimer interface [polypeptide binding]; other site
1157951004873	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1157951004874	heterodimer interface [polypeptide binding]; other site
1157951004875	homodimer interface [polypeptide binding]; other site
1157951004876	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1157951004877	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1157951004878	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1157951004879	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1157951004880	Antibiotic Binding Site [chemical binding]; other site
1157951004881	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1157951004882	G1 box; other site
1157951004883	GTP/Mg2+ binding site [chemical binding]; other site
1157951004884	G2 box; other site
1157951004885	Switch I region; other site
1157951004886	G3 box; other site
1157951004887	Switch II region; other site
1157951004888	G4 box; other site
1157951004889	Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily...; Region: EFG_like_IV; cl02789
1157951004890	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1157951004891	Elongation factor Tu GTP binding domain; Region: GTP_EFTU; pfam00009
1157951004892	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1157951004893	G1 box; other site
1157951004894	putative GEF interaction site [polypeptide binding]; other site
1157951004895	GTP/Mg2+ binding site [chemical binding]; other site
1157951004896	Switch I region; other site
1157951004897	G2 box; other site
1157951004898	G3 box; other site
1157951004899	Switch II region; other site
1157951004900	G4 box; other site
1157951004901	G5 box; other site
1157951004902	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1157951004903	30S ribosomal protein S7; Validated; Region: PRK05302
1157951004904	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1157951004905	S17 interaction site [polypeptide binding]; other site
1157951004906	S8 interaction site; other site
1157951004907	16S rRNA interaction site [nucleotide binding]; other site
1157951004908	streptomycin interaction site [chemical binding]; other site
1157951004909	23S rRNA interaction site [nucleotide binding]; other site
1157951004910	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1157951004911	DsrH like protein; Region: DsrH; cl17347
1157951004912	sulfur relay protein TusC; Validated; Region: PRK00211
1157951004913	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1157951004914	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1157951004915	YheO-like PAS domain; Region: PAS_6; pfam08348
1157951004916	HTH domain; Region: HTH_22; pfam13309
1157951004917	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1157951004918	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1157951004919	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1157951004920	SlyX; Region: SlyX; pfam04102
1157951004921	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1157951004922	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1157951004923	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1157951004924	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1157951004925	TrkA-N domain; Region: TrkA_N; pfam02254
1157951004926	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1157951004927	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1157951004928	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951004929	Walker A/P-loop; other site
1157951004930	ATP binding site [chemical binding]; other site
1157951004931	Q-loop/lid; other site
1157951004932	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951004933	ABC transporter; Region: ABC_tran_2; pfam12848
1157951004934	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951004935	arginine decarboxylase; Provisional; Region: PRK15029
1157951004936	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1157951004937	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1157951004938	homodimer interface [polypeptide binding]; other site
1157951004939	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951004940	catalytic residue [active]
1157951004941	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1157951004942	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1157951004943	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1157951004944	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1157951004945	putative active site [active]
1157951004946	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1157951004947	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1157951004948	putative active site [active]
1157951004949	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1157951004950	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1157951004951	active site turn [active]
1157951004952	phosphorylation site [posttranslational modification]
1157951004953	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1157951004954	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1157951004955	putative hydrolase; Provisional; Region: PRK10985
1157951004956	hypothetical protein; Provisional; Region: PRK04966
1157951004957	phosphoribulokinase; Provisional; Region: PRK15453
1157951004958	hypothetical protein; Provisional; Region: PRK10738
1157951004959	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1157951004960	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1157951004961	ligand binding site [chemical binding]; other site
1157951004962	flexible hinge region; other site
1157951004963	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1157951004964	putative switch regulator; other site
1157951004965	non-specific DNA interactions [nucleotide binding]; other site
1157951004966	DNA binding site [nucleotide binding]
1157951004967	sequence specific DNA binding site [nucleotide binding]; other site
1157951004968	putative cAMP binding site [chemical binding]; other site
1157951004969	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1157951004970	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1157951004971	inhibitor-cofactor binding pocket; inhibition site
1157951004972	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951004973	catalytic residue [active]
1157951004974	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1157951004975	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1157951004976	glutamine binding [chemical binding]; other site
1157951004977	catalytic triad [active]
1157951004978	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1157951004979	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1157951004980	active site
1157951004981	dimer interface [polypeptide binding]; other site
1157951004982	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1157951004983	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1157951004984	intersubunit interface [polypeptide binding]; other site
1157951004985	active site
1157951004986	zinc binding site [ion binding]; other site
1157951004987	Na+ binding site [ion binding]; other site
1157951004988	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1157951004989	active pocket/dimerization site; other site
1157951004990	active site
1157951004991	phosphorylation site [posttranslational modification]
1157951004992	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
1157951004993	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
1157951004994	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1157951004995	active site
1157951004996	phosphorylation site [posttranslational modification]
1157951004997	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
1157951004998	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1157951004999	dimer interface [polypeptide binding]; other site
1157951005000	active site
1157951005001	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
1157951005002	putative active site [active]
1157951005003	Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; pfam08013
1157951005004	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1157951005005	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1157951005006	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1157951005007	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1157951005008	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
1157951005009	active site
1157951005010	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1157951005011	G1 box; other site
1157951005012	GTP/Mg2+ binding site [chemical binding]; other site
1157951005013	Switch I region; other site
1157951005014	G2 box; other site
1157951005015	G3 box; other site
1157951005016	Switch II region; other site
1157951005017	G4 box; other site
1157951005018	G5 box; other site
1157951005019	3-ketoacyl-(acyl-carrier-protein) reductase; Reviewed; Region: PRK12826
1157951005020	classical (c) SDRs; Region: SDR_c; cd05233
1157951005021	NAD(P) binding site [chemical binding]; other site
1157951005022	active site
1157951005023	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1157951005024	DNA polymerase I; Provisional; Region: PRK05755
1157951005025	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1157951005026	active site
1157951005027	metal binding site 1 [ion binding]; metal-binding site
1157951005028	putative 5' ssDNA interaction site; other site
1157951005029	metal binding site 3; metal-binding site
1157951005030	metal binding site 2 [ion binding]; metal-binding site
1157951005031	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1157951005032	putative DNA binding site [nucleotide binding]; other site
1157951005033	putative metal binding site [ion binding]; other site
1157951005034	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1157951005035	active site
1157951005036	catalytic site [active]
1157951005037	substrate binding site [chemical binding]; other site
1157951005038	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1157951005039	active site
1157951005040	DNA binding site [nucleotide binding]
1157951005041	catalytic site [active]
1157951005042	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1157951005043	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1157951005044	catalytic residues [active]
1157951005045	hinge region; other site
1157951005046	alpha helical domain; other site
1157951005047	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1157951005048	serine/threonine protein kinase; Provisional; Region: PRK11768
1157951005049	Protein of unknown function (DUF1040); Region: DUF1040; cl01176
1157951005050	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1157951005051	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1157951005052	GTP binding site; other site
1157951005053	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1157951005054	Walker A motif; other site
1157951005055	glutathione reductase; Validated; Region: PRK06116
1157951005056	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1157951005057	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951005058	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1157951005059	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1157951005060	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1157951005061	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
1157951005062	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
1157951005063	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1157951005064	FMN binding site [chemical binding]; other site
1157951005065	substrate binding site [chemical binding]; other site
1157951005066	putative catalytic residue [active]
1157951005067	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951005068	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951005069	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951005070	dimerization interface [polypeptide binding]; other site
1157951005071	Beta-lactamase; Region: Beta-lactamase; pfam00144
1157951005072	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1157951005073	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1157951005074	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1157951005075	HAMP domain; Region: HAMP; pfam00672
1157951005076	dimerization interface [polypeptide binding]; other site
1157951005077	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1157951005078	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1157951005079	Walker A/P-loop; other site
1157951005080	ATP binding site [chemical binding]; other site
1157951005081	Q-loop/lid; other site
1157951005082	ABC transporter signature motif; other site
1157951005083	Walker B; other site
1157951005084	D-loop; other site
1157951005085	H-loop/switch region; other site
1157951005086	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1157951005087	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1157951005088	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1157951005089	Walker A/P-loop; other site
1157951005090	ATP binding site [chemical binding]; other site
1157951005091	Q-loop/lid; other site
1157951005092	ABC transporter signature motif; other site
1157951005093	Walker B; other site
1157951005094	D-loop; other site
1157951005095	H-loop/switch region; other site
1157951005096	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1157951005097	dipeptide transporter; Provisional; Region: PRK10913
1157951005098	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1157951005099	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951005100	dimer interface [polypeptide binding]; other site
1157951005101	conserved gate region; other site
1157951005102	putative PBP binding loops; other site
1157951005103	ABC-ATPase subunit interface; other site
1157951005104	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1157951005105	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951005106	dimer interface [polypeptide binding]; other site
1157951005107	conserved gate region; other site
1157951005108	putative PBP binding loops; other site
1157951005109	ABC-ATPase subunit interface; other site
1157951005110	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1157951005111	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1157951005112	peptide binding site [polypeptide binding]; other site
1157951005113	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1157951005114	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1157951005115	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1157951005116	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1157951005117	DALR anticodon binding domain; Region: DALR_1; pfam05746
1157951005118	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1157951005119	dimer interface [polypeptide binding]; other site
1157951005120	motif 1; other site
1157951005121	active site
1157951005122	motif 2; other site
1157951005123	motif 3; other site
1157951005124	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1157951005125	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1157951005126	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951005127	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951005128	homodimer interface [polypeptide binding]; other site
1157951005129	catalytic residue [active]
1157951005130	putative transporter; Validated; Region: PRK03818
1157951005131	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1157951005132	TrkA-C domain; Region: TrkA_C; pfam02080
1157951005133	TrkA-C domain; Region: TrkA_C; pfam02080
1157951005134	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1157951005135	Protein of unknown function (DUF1375); Region: DUF1375; cl11456
1157951005136	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1157951005137	Predicted membrane protein [Function unknown]; Region: COG2860
1157951005138	UPF0126 domain; Region: UPF0126; pfam03458
1157951005139	UPF0126 domain; Region: UPF0126; pfam03458
1157951005140	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1157951005141	nucleotide binding pocket [chemical binding]; other site
1157951005142	K-X-D-G motif; other site
1157951005143	catalytic site [active]
1157951005144	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1157951005145	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1157951005146	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1157951005147	catalytic site [active]
1157951005148	G-X2-G-X-G-K; other site
1157951005149	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1157951005150	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1157951005151	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1157951005152	Zn2+ binding site [ion binding]; other site
1157951005153	Mg2+ binding site [ion binding]; other site
1157951005154	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1157951005155	synthetase active site [active]
1157951005156	NTP binding site [chemical binding]; other site
1157951005157	metal binding site [ion binding]; metal-binding site
1157951005158	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1157951005159	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1157951005160	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1157951005161	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1157951005162	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1157951005163	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1157951005164	Y-family of DNA polymerases; Region: PolY; cl12025
1157951005165	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1157951005166	generic binding surface II; other site
1157951005167	ssDNA binding site; other site
1157951005168	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951005169	ATP binding site [chemical binding]; other site
1157951005170	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1157951005171	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951005172	putative Mg++ binding site [ion binding]; other site
1157951005173	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951005174	nucleotide binding region [chemical binding]; other site
1157951005175	ATP-binding site [chemical binding]; other site
1157951005176	Predicted flavoprotein [General function prediction only]; Region: COG0431
1157951005177	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1157951005178	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1157951005179	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1157951005180	AsmA family; Region: AsmA; pfam05170
1157951005181	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1157951005182	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951005183	Coenzyme A binding pocket [chemical binding]; other site
1157951005184	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1157951005185	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1157951005186	putative active site [active]
1157951005187	dimerization interface [polypeptide binding]; other site
1157951005188	putative tRNAtyr binding site [nucleotide binding]; other site
1157951005189	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1157951005190	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1157951005191	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951005192	motif II; other site
1157951005193	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
1157951005194	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951005195	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951005196	dimerization interface [polypeptide binding]; other site
1157951005197	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1157951005198	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
1157951005199	putative metal binding site [ion binding]; other site
1157951005200	dimer interface [polypeptide binding]; other site
1157951005201	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1157951005202	amidohydrolase; Region: amidohydrolases; TIGR01891
1157951005203	putative metal binding site [ion binding]; other site
1157951005204	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
1157951005205	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1157951005206	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1157951005207	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1157951005208	G1 box; other site
1157951005209	putative GEF interaction site [polypeptide binding]; other site
1157951005210	GTP/Mg2+ binding site [chemical binding]; other site
1157951005211	Switch I region; other site
1157951005212	G2 box; other site
1157951005213	G3 box; other site
1157951005214	Switch II region; other site
1157951005215	G4 box; other site
1157951005216	G5 box; other site
1157951005217	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1157951005218	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1157951005219	Predicted transcriptional regulators [Transcription]; Region: COG1695
1157951005220	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1157951005221	glutamine synthetase; Provisional; Region: glnA; PRK09469
1157951005222	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1157951005223	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1157951005224	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1157951005225	PAS domain; Region: PAS; smart00091
1157951005226	putative active site [active]
1157951005227	heme pocket [chemical binding]; other site
1157951005228	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951005229	dimer interface [polypeptide binding]; other site
1157951005230	phosphorylation site [posttranslational modification]
1157951005231	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951005232	ATP binding site [chemical binding]; other site
1157951005233	Mg2+ binding site [ion binding]; other site
1157951005234	G-X-G motif; other site
1157951005235	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1157951005236	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951005237	active site
1157951005238	phosphorylation site [posttranslational modification]
1157951005239	intermolecular recognition site; other site
1157951005240	dimerization interface [polypeptide binding]; other site
1157951005241	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951005242	Walker A motif; other site
1157951005243	ATP binding site [chemical binding]; other site
1157951005244	Walker B motif; other site
1157951005245	arginine finger; other site
1157951005246	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1157951005247	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1157951005248	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951005249	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951005250	dimerization interface [polypeptide binding]; other site
1157951005251	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1157951005252	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
1157951005253	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1157951005254	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951005255	FeS/SAM binding site; other site
1157951005256	HemN C-terminal domain; Region: HemN_C; pfam06969
1157951005257	Der GTPase activator; Provisional; Region: PRK05244
1157951005258	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1157951005259	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1157951005260	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951005261	dimer interface [polypeptide binding]; other site
1157951005262	conserved gate region; other site
1157951005263	putative PBP binding loops; other site
1157951005264	ABC-ATPase subunit interface; other site
1157951005265	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951005266	dimer interface [polypeptide binding]; other site
1157951005267	conserved gate region; other site
1157951005268	putative PBP binding loops; other site
1157951005269	ABC-ATPase subunit interface; other site
1157951005270	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1157951005271	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1157951005272	substrate binding pocket [chemical binding]; other site
1157951005273	membrane-bound complex binding site; other site
1157951005274	hinge residues; other site
1157951005275	transcriptional regulator PhoU; Provisional; Region: PRK11115
1157951005276	PhoU domain; Region: PhoU; pfam01895
1157951005277	PhoU domain; Region: PhoU; pfam01895
1157951005278	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1157951005279	Q-loop/lid; other site
1157951005280	ABC transporter signature motif; other site
1157951005281	Walker B; other site
1157951005282	D-loop; other site
1157951005283	H-loop/switch region; other site
1157951005284	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1157951005285	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951005286	dimer interface [polypeptide binding]; other site
1157951005287	conserved gate region; other site
1157951005288	putative PBP binding loops; other site
1157951005289	ABC-ATPase subunit interface; other site
1157951005290	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1157951005291	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951005292	dimer interface [polypeptide binding]; other site
1157951005293	conserved gate region; other site
1157951005294	putative PBP binding loops; other site
1157951005295	ABC-ATPase subunit interface; other site
1157951005296	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1157951005297	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1157951005298	HAMP domain; Region: HAMP; pfam00672
1157951005299	dimerization interface [polypeptide binding]; other site
1157951005300	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951005301	dimer interface [polypeptide binding]; other site
1157951005302	phosphorylation site [posttranslational modification]
1157951005303	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951005304	ATP binding site [chemical binding]; other site
1157951005305	Mg2+ binding site [ion binding]; other site
1157951005306	G-X-G motif; other site
1157951005307	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1157951005308	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951005309	active site
1157951005310	phosphorylation site [posttranslational modification]
1157951005311	intermolecular recognition site; other site
1157951005312	dimerization interface [polypeptide binding]; other site
1157951005313	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951005314	DNA binding site [nucleotide binding]
1157951005315	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1157951005316	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1157951005317	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1157951005318	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1157951005319	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1157951005320	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1157951005321	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1157951005322	RNA binding site [nucleotide binding]; other site
1157951005323	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1157951005324	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1157951005325	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1157951005326	G1 box; other site
1157951005327	GTP/Mg2+ binding site [chemical binding]; other site
1157951005328	Switch I region; other site
1157951005329	G2 box; other site
1157951005330	G3 box; other site
1157951005331	Switch II region; other site
1157951005332	G4 box; other site
1157951005333	G5 box; other site
1157951005334	Nucleoside recognition; Region: Gate; pfam07670
1157951005335	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1157951005336	Nucleoside recognition; Region: Gate; pfam07670
1157951005337	Virus attachment protein p12 family; Region: P12; pfam12669
1157951005338	FeoC like transcriptional regulator; Region: FeoC; cl17677
1157951005339	carboxylesterase BioH; Provisional; Region: PRK10349
1157951005340	DNA utilization protein GntX; Provisional; Region: PRK11595
1157951005341	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951005342	active site
1157951005343	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1157951005344	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1157951005345	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1157951005346	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1157951005347	active site residue [active]
1157951005348	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1157951005349	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1157951005350	Rhomboid family; Region: Rhomboid; pfam01694
1157951005351	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1157951005352	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1157951005353	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1157951005354	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1157951005355	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951005356	Walker A/P-loop; other site
1157951005357	ATP binding site [chemical binding]; other site
1157951005358	ABC transporter; Region: ABC_tran; pfam00005
1157951005359	Q-loop/lid; other site
1157951005360	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951005361	ABC transporter signature motif; other site
1157951005362	Walker B; other site
1157951005363	D-loop; other site
1157951005364	ABC transporter; Region: ABC_tran_2; pfam12848
1157951005365	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951005366	ABC transporter; Region: ABC_tran; pfam00005
1157951005367	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1157951005368	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1157951005369	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1157951005370	AlkA N-terminal domain; Region: AlkA_N; cl05528
1157951005371	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122
1157951005372	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1157951005373	minor groove reading motif; other site
1157951005374	helix-hairpin-helix signature motif; other site
1157951005375	substrate binding pocket [chemical binding]; other site
1157951005376	active site
1157951005377	pyruvate dehydrogenase; Provisional; Region: PRK09124
1157951005378	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1157951005379	PYR/PP interface [polypeptide binding]; other site
1157951005380	dimer interface [polypeptide binding]; other site
1157951005381	tetramer interface [polypeptide binding]; other site
1157951005382	TPP binding site [chemical binding]; other site
1157951005383	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951005384	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1157951005385	TPP-binding site [chemical binding]; other site
1157951005386	proline/glycine betaine transporter; Provisional; Region: PRK10642
1157951005387	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005388	putative substrate translocation pore; other site
1157951005389	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1157951005390	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1157951005391	DNA photolyase; Region: DNA_photolyase; pfam00875
1157951005392	putative monooxygenase; Provisional; Region: PRK11118
1157951005393	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
1157951005394	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
1157951005395	substrate binding site [chemical binding]; other site
1157951005396	dimer interface [polypeptide binding]; other site
1157951005397	NADP binding site [chemical binding]; other site
1157951005398	catalytic residues [active]
1157951005399	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1157951005400	active site 2 [active]
1157951005401	active site 1 [active]
1157951005402	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
1157951005403	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
1157951005404	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
1157951005405	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
1157951005406	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
1157951005407	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1157951005408	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1157951005409	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1157951005410	FAD binding pocket [chemical binding]; other site
1157951005411	FAD binding motif [chemical binding]; other site
1157951005412	phosphate binding motif [ion binding]; other site
1157951005413	beta-alpha-beta structure motif; other site
1157951005414	NAD(p) ribose binding residues [chemical binding]; other site
1157951005415	NAD binding pocket [chemical binding]; other site
1157951005416	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1157951005417	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1157951005418	catalytic loop [active]
1157951005419	iron binding site [ion binding]; other site
1157951005420	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
1157951005421	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1157951005422	substrate binding site [chemical binding]; other site
1157951005423	oxyanion hole (OAH) forming residues; other site
1157951005424	trimer interface [polypeptide binding]; other site
1157951005425	enoyl-CoA hydratase; Provisional; Region: PRK08140
1157951005426	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1157951005427	substrate binding site [chemical binding]; other site
1157951005428	oxyanion hole (OAH) forming residues; other site
1157951005429	trimer interface [polypeptide binding]; other site
1157951005430	3-hydroxy-acyl-CoA dehydrogenase; Validated; Region: PRK08268
1157951005431	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1157951005432	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1157951005433	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1157951005434	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1157951005435	CoenzymeA binding site [chemical binding]; other site
1157951005436	subunit interaction site [polypeptide binding]; other site
1157951005437	PHB binding site; other site
1157951005438	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1157951005439	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1157951005440	dimer interface [polypeptide binding]; other site
1157951005441	active site
1157951005442	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
1157951005443	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
1157951005444	active site
1157951005445	AMP binding site [chemical binding]; other site
1157951005446	homodimer interface [polypeptide binding]; other site
1157951005447	acyl-activating enzyme (AAE) consensus motif; other site
1157951005448	CoA binding site [chemical binding]; other site
1157951005449	PaaX-like protein; Region: PaaX; pfam07848
1157951005450	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
1157951005451	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
1157951005452	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
1157951005453	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1157951005454	putative trimer interface [polypeptide binding]; other site
1157951005455	putative metal binding site [ion binding]; other site
1157951005456	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951005457	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951005458	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951005459	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951005460	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951005461	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951005462	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951005463	Fimbrial protein; Region: Fimbrial; pfam00419
1157951005464	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1157951005465	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005466	putative substrate translocation pore; other site
1157951005467	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1157951005468	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951005469	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951005470	glycogen branching enzyme; Provisional; Region: PRK05402
1157951005471	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1157951005472	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1157951005473	active site
1157951005474	catalytic site [active]
1157951005475	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1157951005476	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1157951005477	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1157951005478	ADP-binding pocket [chemical binding]; other site
1157951005479	homodimer interface [polypeptide binding]; other site
1157951005480	PAAR motif; Region: PAAR_motif; pfam05488
1157951005481	PAAR motif; Region: PAAR_motif; pfam05488
1157951005482	PAAR motif; Region: PAAR_motif; pfam05488
1157951005483	Domain of unknown function (DUF4279); Region: DUF4279; pfam14106
1157951005484	S-type Pyocin; Region: Pyocin_S; pfam06958
1157951005485	Domain of unknown function (DUF4123); Region: DUF4123; pfam13503
1157951005486	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1157951005487	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1157951005488	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1157951005489	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733
1157951005490	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1157951005491	Bacterial protein of unknown function (DUF879); Region: DUF879; cl15462
1157951005492	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1157951005493	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1157951005494	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1157951005495	ImpA domain protein; Region: DUF3702; pfam12486
1157951005496	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1157951005497	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1157951005498	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1157951005499	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1157951005500	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1157951005501	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1157951005502	Protein of unknown function (DUF3121); Region: DUF3121; pfam11319
1157951005503	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1157951005504	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1157951005505	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951005506	Walker A motif; other site
1157951005507	ATP binding site [chemical binding]; other site
1157951005508	Walker B motif; other site
1157951005509	arginine finger; other site
1157951005510	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951005511	Walker A motif; other site
1157951005512	ATP binding site [chemical binding]; other site
1157951005513	Walker B motif; other site
1157951005514	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1157951005515	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
1157951005516	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1157951005517	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1157951005518	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522; cl01406
1157951005519	Type VI secretion lipoprotein; Region: T6SS-SciN; cl01405
1157951005520	type VI secretion system FHA domain protein; Region: VI_FHA; TIGR03354
1157951005521	FHA domain; Region: FHA; pfam00498
1157951005522	phosphopeptide binding site; other site
1157951005523	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1157951005524	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1157951005525	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1157951005526	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1157951005527	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1157951005528	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1157951005529	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1157951005530	Glycoside hydrolase family 15, N-terminal domain; Region: GH15_N; cd07430
1157951005531	Domain interface; other site
1157951005532	glucan 1,4-alpha-glucosidase; Region: glucan_glucosid; TIGR01535
1157951005533	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
1157951005534	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1157951005535	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1157951005536	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1157951005537	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
1157951005538	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1157951005539	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1157951005540	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1157951005541	nucleotide binding site [chemical binding]; other site
1157951005542	putative transporter; Provisional; Region: PRK12382
1157951005543	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005544	putative substrate translocation pore; other site
1157951005545	putative iron-regulated outer membrane virulence protein; Provisional; Region: PRK13484
1157951005546	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951005547	N-terminal plug; other site
1157951005548	ligand-binding site [chemical binding]; other site
1157951005549	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1157951005550	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1157951005551	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951005552	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951005553	dimerization interface [polypeptide binding]; other site
1157951005554	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1157951005555	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1157951005556	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1157951005557	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1157951005558	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
1157951005559	CoA binding domain; Region: CoA_binding; pfam02629
1157951005560	CoA-ligase; Region: Ligase_CoA; pfam00549
1157951005561	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1157951005562	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1157951005563	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1157951005564	putative substrate binding site [chemical binding]; other site
1157951005565	nucleotide binding site [chemical binding]; other site
1157951005566	nucleotide binding site [chemical binding]; other site
1157951005567	homodimer interface [polypeptide binding]; other site
1157951005568	putative deaminase; Validated; Region: PRK06846
1157951005569	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1157951005570	active site
1157951005571	mannonate dehydratase; Provisional; Region: PRK03906
1157951005572	mannonate dehydratase; Region: uxuA; TIGR00695
1157951005573	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005574	D-galactonate transporter; Region: 2A0114; TIGR00893
1157951005575	putative substrate translocation pore; other site
1157951005576	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1157951005577	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951005578	DNA-binding site [nucleotide binding]; DNA binding site
1157951005579	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1157951005580	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1157951005581	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005582	putative substrate translocation pore; other site
1157951005583	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1157951005584	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1157951005585	active site
1157951005586	dimerization interface [polypeptide binding]; other site
1157951005587	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1157951005588	Salmonella-Shigella invasin protein C (IpaC_SipC); Region: IpaC_SipC; cl10712
1157951005589	Salmonella-Shigella invasin protein C (IpaC_SipC); Region: IpaC_SipC; cl10712
1157951005590	Ulp1 protease family, C-terminal catalytic domain; Region: Peptidase_C48; cl17784
1157951005591	chaperone protein SicA; Provisional; Region: PRK15331
1157951005592	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1157951005593	binding surface
1157951005594	TPR motif; other site
1157951005595	type III secretion system protein SpaS; Validated; Region: PRK08156
1157951005596	type III secretion system protein SpaS; Validated; Region: PRK08156
1157951005597	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
1157951005598	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1157951005599	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1157951005600	type III secretion system protein SpaO; Validated; Region: PRK08158
1157951005601	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1157951005602	ATP synthase SpaL; Validated; Region: PRK08149
1157951005603	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1157951005604	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1157951005605	Walker A motif; other site
1157951005606	ATP binding site [chemical binding]; other site
1157951005607	Walker B motif; other site
1157951005608	Invasion protein B family; Region: Invas_SpaK; cl04129
1157951005609	type III secretion system protein InvA; Provisional; Region: PRK15337
1157951005610	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980
1157951005611	HrpJ-like domain; Region: HrpJ; pfam07201
1157951005612	type III secretion system regulator InvE; Provisional; Region: PRK15338
1157951005613	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
1157951005614	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1157951005615	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1157951005616	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1157951005617	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1157951005618	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951005619	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
1157951005620	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1157951005621	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1157951005622	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1157951005623	Bacterial type III secretion apparatus protein (OrgA_MxiK); Region: OrgA_MxiK; cl09716
1157951005624	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1157951005625	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005626	putative substrate translocation pore; other site
1157951005627	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1157951005628	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951005629	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951005630	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951005631	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
1157951005632	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1157951005633	DNA-binding site [nucleotide binding]; DNA binding site
1157951005634	RNA-binding motif; other site
1157951005635	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1157951005636	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1157951005637	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1157951005638	putative active site [active]
1157951005639	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1157951005640	PTS system, maltose and glucose-specific IIBC component; Region: PTS-IIBC-malX; TIGR02004
1157951005641	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1157951005642	active site turn [active]
1157951005643	phosphorylation site [posttranslational modification]
1157951005644	prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597
1157951005645	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
1157951005646	tetramer interface [polypeptide binding]; other site
1157951005647	active site
1157951005648	Transposase; Region: HTH_Tnp_1; cl17663
1157951005649	oligopeptidase A; Provisional; Region: PRK10911
1157951005650	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1157951005651	active site
1157951005652	Zn binding site [ion binding]; other site
1157951005653	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951005654	S-adenosylmethionine binding site [chemical binding]; other site
1157951005655	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1157951005656	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1157951005657	Class I aldolases; Region: Aldolase_Class_I; cl17187
1157951005658	catalytic residue [active]
1157951005659	Glycerol-3-phosphate responsive antiterminator; Region: G3P_antiterm; cl00852
1157951005660	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1157951005661	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1157951005662	putative N- and C-terminal domain interface [polypeptide binding]; other site
1157951005663	putative active site [active]
1157951005664	MgATP binding site [chemical binding]; other site
1157951005665	catalytic site [active]
1157951005666	metal binding site [ion binding]; metal-binding site
1157951005667	putative xylulose binding site [chemical binding]; other site
1157951005668	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1157951005669	classical (c) SDRs; Region: SDR_c; cd05233
1157951005670	NAD(P) binding site [chemical binding]; other site
1157951005671	active site
1157951005672	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
1157951005673	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1157951005674	putative ligand binding site [chemical binding]; other site
1157951005675	putative NAD binding site [chemical binding]; other site
1157951005676	catalytic site [active]
1157951005677	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1157951005678	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1157951005679	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1157951005680	AAA domain; Region: AAA_12; pfam13087
1157951005681	Putative SAM-dependent methyltransferase; Region: SAM_MT; cl17517
1157951005682	glutamate dehydrogenase; Provisional; Region: PRK09414
1157951005683	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1157951005684	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1157951005685	NAD(P) binding site [chemical binding]; other site
1157951005686	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1157951005687	Ligand Binding Site [chemical binding]; other site
1157951005688	universal stress protein UspB; Provisional; Region: PRK04960
1157951005689	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1157951005690	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1157951005691	Predicted flavoproteins [General function prediction only]; Region: COG2081
1157951005692	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1157951005693	Pirin-related protein [General function prediction only]; Region: COG1741
1157951005694	Pirin; Region: Pirin; pfam02678
1157951005695	Pirin-related protein [General function prediction only]; Region: COG1741
1157951005696	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1157951005697	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1157951005698	active site
1157951005699	substrate-binding site [chemical binding]; other site
1157951005700	metal-binding site [ion binding]
1157951005701	ATP binding site [chemical binding]; other site
1157951005702	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1157951005703	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1157951005704	dimerization interface [polypeptide binding]; other site
1157951005705	domain crossover interface; other site
1157951005706	redox-dependent activation switch; other site
1157951005707	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1157951005708	RNA binding surface [nucleotide binding]; other site
1157951005709	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1157951005710	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1157951005711	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1157951005712	dimer interface [polypeptide binding]; other site
1157951005713	ADP-ribose binding site [chemical binding]; other site
1157951005714	active site
1157951005715	nudix motif; other site
1157951005716	metal binding site [ion binding]; metal-binding site
1157951005717	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1157951005718	Transglycosylase; Region: Transgly; pfam00912
1157951005719	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1157951005720	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1157951005721	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1157951005722	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1157951005723	Pilus assembly protein, PilO; Region: PilO; cl01234
1157951005724	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1157951005725	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
1157951005726	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1157951005727	shikimate kinase; Reviewed; Region: aroK; PRK00131
1157951005728	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1157951005729	ADP binding site [chemical binding]; other site
1157951005730	magnesium binding site [ion binding]; other site
1157951005731	putative shikimate binding site; other site
1157951005732	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1157951005733	active site
1157951005734	dimer interface [polypeptide binding]; other site
1157951005735	metal binding site [ion binding]; metal-binding site
1157951005736	hypothetical protein; Reviewed; Region: PRK11901
1157951005737	cell division protein DamX; Validated; Region: PRK10905
1157951005738	DNA adenine methylase; Provisional; Region: PRK10904
1157951005739	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1157951005740	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1157951005741	substrate binding site [chemical binding]; other site
1157951005742	hexamer interface [polypeptide binding]; other site
1157951005743	metal binding site [ion binding]; metal-binding site
1157951005744	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1157951005745	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951005746	motif II; other site
1157951005747	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1157951005748	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1157951005749	active site
1157951005750	HIGH motif; other site
1157951005751	dimer interface [polypeptide binding]; other site
1157951005752	KMSKS motif; other site
1157951005753	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1157951005754	classical (c) SDRs; Region: SDR_c; cd05233
1157951005755	NAD(P) binding site [chemical binding]; other site
1157951005756	active site
1157951005757	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
1157951005758	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
1157951005759	teramer interface [polypeptide binding]; other site
1157951005760	active site
1157951005761	FMN binding site [chemical binding]; other site
1157951005762	catalytic residues [active]
1157951005763	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1157951005764	Isochorismatase family; Region: Isochorismatase; pfam00857
1157951005765	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1157951005766	catalytic triad [active]
1157951005767	dimer interface [polypeptide binding]; other site
1157951005768	conserved cis-peptide bond; other site
1157951005769	Pirin-related protein [General function prediction only]; Region: COG1741
1157951005770	Pirin; Region: Pirin; pfam02678
1157951005771	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1157951005772	LysR family transcriptional regulator; Provisional; Region: PRK14997
1157951005773	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951005774	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951005775	dimerization interface [polypeptide binding]; other site
1157951005776	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1157951005777	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951005778	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1157951005779	Walker A/P-loop; other site
1157951005780	ATP binding site [chemical binding]; other site
1157951005781	Q-loop/lid; other site
1157951005782	ABC transporter signature motif; other site
1157951005783	Walker B; other site
1157951005784	D-loop; other site
1157951005785	H-loop/switch region; other site
1157951005786	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1157951005787	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1157951005788	Walker A/P-loop; other site
1157951005789	ATP binding site [chemical binding]; other site
1157951005790	Q-loop/lid; other site
1157951005791	ABC transporter signature motif; other site
1157951005792	Walker B; other site
1157951005793	D-loop; other site
1157951005794	H-loop/switch region; other site
1157951005795	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1157951005796	MOSC domain; Region: MOSC; pfam03473
1157951005797	3-alpha domain; Region: 3-alpha; pfam03475
1157951005798	DnaJ domain; Region: DnaJ; pfam00226
1157951005799	HSP70 interaction site [polypeptide binding]; other site
1157951005800	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1157951005801	Fe-S protein assembly chaperone HscA; Region: HscA; TIGR01991
1157951005802	nucleotide binding site [chemical binding]; other site
1157951005803	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1157951005804	SBD interface [polypeptide binding]; other site
1157951005805	superoxide dismutase; Provisional; Region: PRK10925
1157951005806	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1157951005807	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1157951005808	acetyl-CoA synthetase; Provisional; Region: PRK00174
1157951005809	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1157951005810	active site
1157951005811	CoA binding site [chemical binding]; other site
1157951005812	acyl-activating enzyme (AAE) consensus motif; other site
1157951005813	AMP binding site [chemical binding]; other site
1157951005814	acetate binding site [chemical binding]; other site
1157951005815	Predicted membrane protein [Function unknown]; Region: COG3162
1157951005816	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1157951005817	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1157951005818	Na binding site [ion binding]; other site
1157951005819	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1157951005820	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951005821	DNA-binding site [nucleotide binding]; DNA binding site
1157951005822	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1157951005823	putative transporter; Provisional; Region: PRK10504
1157951005824	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005825	transcriptional repressor RbsR; Provisional; Region: PRK10423
1157951005826	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951005827	DNA binding site [nucleotide binding]
1157951005828	domain linker motif; other site
1157951005829	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1157951005830	dimerization interface [polypeptide binding]; other site
1157951005831	ligand binding site [chemical binding]; other site
1157951005832	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1157951005833	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1157951005834	substrate binding site [chemical binding]; other site
1157951005835	dimer interface [polypeptide binding]; other site
1157951005836	ATP binding site [chemical binding]; other site
1157951005837	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1157951005838	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1157951005839	ligand binding site [chemical binding]; other site
1157951005840	dimerization interface [polypeptide binding]; other site
1157951005841	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1157951005842	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1157951005843	TM-ABC transporter signature motif; other site
1157951005844	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1157951005845	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1157951005846	Walker A/P-loop; other site
1157951005847	ATP binding site [chemical binding]; other site
1157951005848	Q-loop/lid; other site
1157951005849	ABC transporter signature motif; other site
1157951005850	Walker B; other site
1157951005851	D-loop; other site
1157951005852	H-loop/switch region; other site
1157951005853	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1157951005854	D-ribose pyranase; Provisional; Region: PRK11797
1157951005855	regulatory ATPase RavA; Provisional; Region: PRK13531
1157951005856	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951005857	Walker A motif; other site
1157951005858	ATP binding site [chemical binding]; other site
1157951005859	Walker B motif; other site
1157951005860	arginine finger; other site
1157951005861	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1157951005862	hypothetical protein; Provisional; Region: yieM; PRK10997
1157951005863	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1157951005864	metal ion-dependent adhesion site (MIDAS); other site
1157951005865	Asparagine synthetase A [Amino acid transport and metabolism]; Region: AsnA; COG2502
1157951005866	motif 1; other site
1157951005867	dimer interface [polypeptide binding]; other site
1157951005868	active site
1157951005869	motif 2; other site
1157951005870	motif 3; other site
1157951005871	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1157951005872	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1157951005873	putative DNA binding site [nucleotide binding]; other site
1157951005874	putative Zn2+ binding site [ion binding]; other site
1157951005875	AsnC family; Region: AsnC_trans_reg; pfam01037
1157951005876	FMN-binding protein MioC; Provisional; Region: PRK09004
1157951005877	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1157951005878	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1157951005879	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1157951005880	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1157951005881	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1157951005882	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1157951005883	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1157951005884	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1157951005885	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1157951005886	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1157951005887	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1157951005888	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1157951005889	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1157951005890	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1157951005891	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1157951005892	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1157951005893	beta subunit interaction interface [polypeptide binding]; other site
1157951005894	Walker A motif; other site
1157951005895	ATP binding site [chemical binding]; other site
1157951005896	Walker B motif; other site
1157951005897	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1157951005898	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1157951005899	core domain interface [polypeptide binding]; other site
1157951005900	delta subunit interface [polypeptide binding]; other site
1157951005901	epsilon subunit interface [polypeptide binding]; other site
1157951005902	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1157951005903	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1157951005904	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1157951005905	alpha subunit interaction interface [polypeptide binding]; other site
1157951005906	Walker A motif; other site
1157951005907	ATP binding site [chemical binding]; other site
1157951005908	Walker B motif; other site
1157951005909	inhibitor binding site; inhibition site
1157951005910	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1157951005911	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1157951005912	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1157951005913	gamma subunit interface [polypeptide binding]; other site
1157951005914	epsilon subunit interface [polypeptide binding]; other site
1157951005915	LBP interface [polypeptide binding]; other site
1157951005916	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1157951005917	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1157951005918	Substrate binding site; other site
1157951005919	Mg++ binding site; other site
1157951005920	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1157951005921	active site
1157951005922	substrate binding site [chemical binding]; other site
1157951005923	CoA binding site [chemical binding]; other site
1157951005924	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1157951005925	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1157951005926	glutaminase active site [active]
1157951005927	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1157951005928	dimer interface [polypeptide binding]; other site
1157951005929	active site
1157951005930	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1157951005931	dimer interface [polypeptide binding]; other site
1157951005932	active site
1157951005933	ParB-like nuclease domain; Region: ParBc; cl02129
1157951005934	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1157951005935	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
1157951005936	putative ligand binding residues [chemical binding]; other site
1157951005937	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951005938	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005939	putative substrate translocation pore; other site
1157951005940	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1157951005941	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; Region: Octopine_DH; pfam02317
1157951005942	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1157951005943	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1157951005944	dimer interface [polypeptide binding]; other site
1157951005945	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951005946	catalytic residue [active]
1157951005947	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1157951005948	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Y4yA; Region: PLPDE_III_Y4yA_like; cd06842
1157951005949	dimer interface [polypeptide binding]; other site
1157951005950	active site
1157951005951	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1157951005952	catalytic residues [active]
1157951005953	substrate binding site [chemical binding]; other site
1157951005954	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1157951005955	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951005956	N-terminal plug; other site
1157951005957	ligand-binding site [chemical binding]; other site
1157951005958	IucA / IucC family; Region: IucA_IucC; pfam04183
1157951005959	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1157951005960	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1157951005961	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1157951005962	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951005963	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1157951005964	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005965	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951005966	putative substrate translocation pore; other site
1157951005967	Putative transcriptional regulators (Ypuh-like); Region: DUF387; cl00612
1157951005968	Predicted transcriptional regulator [Transcription]; Region: COG2345
1157951005969	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
1157951005970	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1157951005971	Penicillin G acylase (PGA) is the key enzyme in the industrial production of beta-lactam antibiotics. PGA hydrolyzes the side chain of penicillin G and related beta-lactam antibiotics releasing 6-amino penicillanic acid (6-APA), a building block in the...; Region: Ntn_PGA; cd03748
1157951005972	active site
1157951005973	Rhomboid family; Region: Rhomboid; cl11446
1157951005974	ATPase involved in DNA repair; Region: DUF3686; pfam12458
1157951005975	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
1157951005976	linker region; other site
1157951005977	AAA domain; Region: AAA_22; pfam13401
1157951005978	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1157951005979	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1157951005980	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1157951005981	Bacillus haemolytic enterotoxin (HBL); Region: Bacillus_HBL; pfam05791
1157951005982	fructokinase; Reviewed; Region: PRK09557
1157951005983	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1157951005984	nucleotide binding site [chemical binding]; other site
1157951005985	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1157951005986	catalytic triad [active]
1157951005987	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1157951005988	active site
1157951005989	oxyanion hole [active]
1157951005990	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1157951005991	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1157951005992	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1157951005993	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1157951005994	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1157951005995	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1157951005996	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1157951005997	MarR family; Region: MarR_2; pfam12802
1157951005998	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1157951005999	Sulfatase; Region: Sulfatase; pfam00884
1157951006000	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1157951006001	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951006002	ATP binding site [chemical binding]; other site
1157951006003	Mg2+ binding site [ion binding]; other site
1157951006004	G-X-G motif; other site
1157951006005	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1157951006006	anchoring element; other site
1157951006007	dimer interface [polypeptide binding]; other site
1157951006008	ATP binding site [chemical binding]; other site
1157951006009	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1157951006010	active site
1157951006011	putative metal-binding site [ion binding]; other site
1157951006012	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1157951006013	recF protein; Region: recf; TIGR00611
1157951006014	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951006015	Walker A/P-loop; other site
1157951006016	ATP binding site [chemical binding]; other site
1157951006017	Q-loop/lid; other site
1157951006018	ABC transporter signature motif; other site
1157951006019	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951006020	ABC transporter signature motif; other site
1157951006021	Walker B; other site
1157951006022	D-loop; other site
1157951006023	H-loop/switch region; other site
1157951006024	DNA polymerase III subunit beta; Validated; Region: PRK05643
1157951006025	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1157951006026	putative DNA binding surface [nucleotide binding]; other site
1157951006027	dimer interface [polypeptide binding]; other site
1157951006028	beta-clamp/clamp loader binding surface; other site
1157951006029	beta-clamp/translesion DNA polymerase binding surface; other site
1157951006030	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1157951006031	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1157951006032	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951006033	Walker A motif; other site
1157951006034	ATP binding site [chemical binding]; other site
1157951006035	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1157951006036	Walker B motif; other site
1157951006037	arginine finger; other site
1157951006038	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1157951006039	DnaA box-binding interface [nucleotide binding]; other site
1157951006040	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1157951006041	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1157951006042	Haemolytic domain; Region: Haemolytic; pfam01809
1157951006043	membrane protein insertase; Provisional; Region: PRK01318
1157951006044	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1157951006045	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1157951006046	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1157951006047	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1157951006048	G1 box; other site
1157951006049	GTP/Mg2+ binding site [chemical binding]; other site
1157951006050	Switch I region; other site
1157951006051	G2 box; other site
1157951006052	Switch II region; other site
1157951006053	G3 box; other site
1157951006054	G4 box; other site
1157951006055	G5 box; other site
1157951006056	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1157951006057	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1157951006058	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951006059	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951006060	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1157951006061	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1157951006062	molybdopterin cofactor binding site; other site
1157951006063	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1157951006064	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1157951006065	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1157951006066	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1157951006067	formyl-coenzyme A transferase; Provisional; Region: PRK05398
1157951006068	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1157951006069	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
1157951006070	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1157951006071	PYR/PP interface [polypeptide binding]; other site
1157951006072	dimer interface [polypeptide binding]; other site
1157951006073	TPP binding site [chemical binding]; other site
1157951006074	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951006075	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
1157951006076	TPP-binding site; other site
1157951006077	dimer interface [polypeptide binding]; other site
1157951006078	Membrane transport protein; Region: Mem_trans; cl09117
1157951006079	formyl-coenzyme A transferase; Provisional; Region: PRK05398
1157951006080	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1157951006081	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1157951006082	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1157951006083	active site
1157951006084	catalytic triad [active]
1157951006085	dimer interface [polypeptide binding]; other site
1157951006086	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1157951006087	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1157951006088	active site
1157951006089	catalytic triad [active]
1157951006090	dimer interface [polypeptide binding]; other site
1157951006091	potential frameshift: common BLAST hit: gi|375356907|ref|YP_005109679.1| putative ion transport protein
1157951006092	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1157951006093	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1157951006094	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1157951006095	selenocysteine synthase; Provisional; Region: PRK04311
1157951006096	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1157951006097	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1157951006098	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1157951006099	G1 box; other site
1157951006100	GTP/Mg2+ binding site [chemical binding]; other site
1157951006101	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1157951006102	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1157951006103	G2 box; other site
1157951006104	Switch I region; other site
1157951006105	G3 box; other site
1157951006106	Switch II region; other site
1157951006107	GTP/Mg2+ binding site [chemical binding]; other site
1157951006108	G4 box; other site
1157951006109	G5 box; other site
1157951006110	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1157951006111	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1157951006112	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1157951006113	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1157951006114	Sulfatase; Region: Sulfatase; cl17466
1157951006115	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1157951006116	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
1157951006117	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1157951006118	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951006119	DNA-binding site [nucleotide binding]; DNA binding site
1157951006120	UTRA domain; Region: UTRA; pfam07702
1157951006121	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1157951006122	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1157951006123	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1157951006124	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1157951006125	substrate binding site [chemical binding]; other site
1157951006126	ATP binding site [chemical binding]; other site
1157951006127	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1157951006128	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
1157951006129	putative NAD(P) binding site [chemical binding]; other site
1157951006130	active site
1157951006131	putative substrate binding site [chemical binding]; other site
1157951006132	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1157951006133	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1157951006134	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1157951006135	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1157951006136	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; cl17526
1157951006137	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1157951006138	substrate binding site [chemical binding]; other site
1157951006139	multimerization interface [polypeptide binding]; other site
1157951006140	ATP binding site [chemical binding]; other site
1157951006141	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1157951006142	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1157951006143	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1157951006144	nucleoside transporter; Region: 2A0110; TIGR00889
1157951006145	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1157951006146	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1157951006147	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1157951006148	intersubunit interface [polypeptide binding]; other site
1157951006149	hypothetical protein; Provisional; Region: PRK11820
1157951006150	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1157951006151	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1157951006152	ribonuclease PH; Reviewed; Region: rph; PRK00173
1157951006153	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1157951006154	hexamer interface [polypeptide binding]; other site
1157951006155	active site
1157951006156	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951006157	active site
1157951006158	division inhibitor protein; Provisional; Region: slmA; PRK09480
1157951006159	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951006160	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1157951006161	trimer interface [polypeptide binding]; other site
1157951006162	active site
1157951006163	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1157951006164	Flavoprotein; Region: Flavoprotein; pfam02441
1157951006165	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1157951006166	hypothetical protein; Reviewed; Region: PRK00024
1157951006167	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1157951006168	MPN+ (JAMM) motif; other site
1157951006169	Zinc-binding site [ion binding]; other site
1157951006170	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1157951006171	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1157951006172	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1157951006173	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1157951006174	putative active site [active]
1157951006175	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1157951006176	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1157951006177	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1157951006178	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1157951006179	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1157951006180	Ligand binding site; other site
1157951006181	metal-binding site
1157951006182	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1157951006183	O-Antigen ligase; Region: Wzy_C; cl04850
1157951006184	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1157951006185	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1157951006186	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1157951006187	Ligand binding site; other site
1157951006188	metal-binding site
1157951006189	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1157951006190	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1157951006191	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1157951006192	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1157951006193	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1157951006194	Ligand binding site; other site
1157951006195	metal-binding site
1157951006196	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1157951006197	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1157951006198	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1157951006199	DNA binding site [nucleotide binding]
1157951006200	catalytic residue [active]
1157951006201	H2TH interface [polypeptide binding]; other site
1157951006202	putative catalytic residues [active]
1157951006203	turnover-facilitating residue; other site
1157951006204	intercalation triad [nucleotide binding]; other site
1157951006205	8OG recognition residue [nucleotide binding]; other site
1157951006206	putative reading head residues; other site
1157951006207	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1157951006208	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1157951006209	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1157951006210	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1157951006211	active site
1157951006212	(T/H)XGH motif; other site
1157951006213	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1157951006214	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1157951006215	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cd01635
1157951006216	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1157951006217	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1157951006218	Bacterial protein of unknown function (HtrL_YibB); Region: HtrL_YibB; cl08171
1157951006219	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1157951006220	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1157951006221	putative active site [active]
1157951006222	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1157951006223	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1157951006224	putative active site [active]
1157951006225	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1157951006226	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1157951006227	NADP binding site [chemical binding]; other site
1157951006228	homopentamer interface [polypeptide binding]; other site
1157951006229	substrate binding site [chemical binding]; other site
1157951006230	active site
1157951006231	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1157951006232	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1157951006233	substrate-cofactor binding pocket; other site
1157951006234	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951006235	catalytic residue [active]
1157951006236	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1157951006237	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1157951006238	NAD(P) binding site [chemical binding]; other site
1157951006239	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1157951006240	putative active site [active]
1157951006241	Divergent polysaccharide deacetylase; Region: Polysacc_deac_2; cl17042
1157951006242	AmiB activator; Provisional; Region: PRK11637
1157951006243	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1157951006244	Peptidase family M23; Region: Peptidase_M23; pfam01551
1157951006245	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1157951006246	active site residue [active]
1157951006247	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1157951006248	SecA binding site; other site
1157951006249	Preprotein binding site; other site
1157951006250	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1157951006251	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1157951006252	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1157951006253	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1157951006254	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1157951006255	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1157951006256	trimer interface [polypeptide binding]; other site
1157951006257	active site
1157951006258	substrate binding site [chemical binding]; other site
1157951006259	CoA binding site [chemical binding]; other site
1157951006260	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1157951006261	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1157951006262	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1157951006263	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1157951006264	UDP-glucose 4-epimerase; Region: PLN02240
1157951006265	NAD binding site [chemical binding]; other site
1157951006266	homodimer interface [polypeptide binding]; other site
1157951006267	active site
1157951006268	substrate binding site [chemical binding]; other site
1157951006269	tyrosine kinase; Provisional; Region: PRK11519
1157951006270	Chain length determinant protein; Region: Wzz; pfam02706
1157951006271	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1157951006272	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1157951006273	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1157951006274	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1157951006275	active site
1157951006276	polysaccharide export protein Wza; Provisional; Region: PRK15078
1157951006277	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1157951006278	SLBB domain; Region: SLBB; pfam10531
1157951006279	SLBB domain; Region: SLBB; pfam10531
1157951006280	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1157951006281	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1157951006282	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1157951006283	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1157951006284	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1157951006285	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1157951006286	putative ADP-binding pocket [chemical binding]; other site
1157951006287	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1157951006288	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1157951006289	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1157951006290	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1157951006291	NAD(P) binding site [chemical binding]; other site
1157951006292	active site
1157951006293	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1157951006294	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1157951006295	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1157951006296	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1157951006297	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1157951006298	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1157951006299	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
1157951006300	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1157951006301	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1157951006302	dimerization interface [polypeptide binding]; other site
1157951006303	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951006304	dimer interface [polypeptide binding]; other site
1157951006305	phosphorylation site [posttranslational modification]
1157951006306	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951006307	ATP binding site [chemical binding]; other site
1157951006308	Mg2+ binding site [ion binding]; other site
1157951006309	G-X-G motif; other site
1157951006310	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1157951006311	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951006312	active site
1157951006313	intermolecular recognition site; other site
1157951006314	dimerization interface [polypeptide binding]; other site
1157951006315	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951006316	DNA binding site [nucleotide binding]
1157951006317	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1157951006318	dimer interface [polypeptide binding]; other site
1157951006319	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1157951006320	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1157951006321	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1157951006322	putative acyl-acceptor binding pocket; other site
1157951006323	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
1157951006324	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1157951006325	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1157951006326	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1157951006327	active site
1157951006328	ADP/pyrophosphate binding site [chemical binding]; other site
1157951006329	dimerization interface [polypeptide binding]; other site
1157951006330	allosteric effector site; other site
1157951006331	fructose-1,6-bisphosphate binding site; other site
1157951006332	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1157951006333	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1157951006334	substrate binding pocket [chemical binding]; other site
1157951006335	membrane-bound complex binding site; other site
1157951006336	hinge residues; other site
1157951006337	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1157951006338	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1157951006339	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
1157951006340	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1157951006341	triosephosphate isomerase; Provisional; Region: PRK14567
1157951006342	substrate binding site [chemical binding]; other site
1157951006343	dimer interface [polypeptide binding]; other site
1157951006344	catalytic triad [active]
1157951006345	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1157951006346	Predicted membrane protein [Function unknown]; Region: COG3152
1157951006347	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1157951006348	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1157951006349	FAD binding pocket [chemical binding]; other site
1157951006350	FAD binding motif [chemical binding]; other site
1157951006351	phosphate binding motif [ion binding]; other site
1157951006352	beta-alpha-beta structure motif; other site
1157951006353	NAD binding pocket [chemical binding]; other site
1157951006354	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1157951006355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951006356	putative substrate translocation pore; other site
1157951006357	glycerol kinase; Region: glycerol_kin; TIGR01311
1157951006358	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1157951006359	homotetramer interface [polypeptide binding]; other site
1157951006360	N- and C-terminal domain interface [polypeptide binding]; other site
1157951006361	active site
1157951006362	glycerol binding site [chemical binding]; other site
1157951006363	homodimer interface [polypeptide binding]; other site
1157951006364	FBP binding site [chemical binding]; other site
1157951006365	MgATP binding site [chemical binding]; other site
1157951006366	protein IIAGlc interface [polypeptide binding]; other site
1157951006367	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1157951006368	amphipathic channel; other site
1157951006369	Asn-Pro-Ala signature motifs; other site
1157951006370	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3074
1157951006371	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1157951006372	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1157951006373	UbiA prenyltransferase family; Region: UbiA; pfam01040
1157951006374	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1157951006375	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951006376	Walker A motif; other site
1157951006377	ATP binding site [chemical binding]; other site
1157951006378	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1157951006379	Walker B motif; other site
1157951006380	arginine finger; other site
1157951006381	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1157951006382	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1157951006383	active site
1157951006384	HslU subunit interaction site [polypeptide binding]; other site
1157951006385	Sporulation related domain; Region: SPOR; cl10051
1157951006386	cell division protein FtsN; Provisional; Region: PRK12757
1157951006387	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951006388	DNA binding site [nucleotide binding]
1157951006389	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1157951006390	domain linker motif; other site
1157951006391	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1157951006392	dimerization interface [polypeptide binding]; other site
1157951006393	ligand binding site [chemical binding]; other site
1157951006394	Transposase; Region: HTH_Tnp_1; cl17663
1157951006395	IS2 transposase TnpB; Reviewed; Region: PRK09409
1157951006396	HTH-like domain; Region: HTH_21; pfam13276
1157951006397	Integrase core domain; Region: rve; pfam00665
1157951006398	Integrase core domain; Region: rve_3; pfam13683
1157951006399	RHS protein; Region: RHS; pfam03527
1157951006400	PAAR motif; Region: PAAR_motif; pfam05488
1157951006401	RHS Repeat; Region: RHS_repeat; pfam05593
1157951006402	RHS Repeat; Region: RHS_repeat; cl11982
1157951006403	RHS Repeat; Region: RHS_repeat; pfam05593
1157951006404	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1157951006405	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1157951006406	RHS Repeat; Region: RHS_repeat; pfam05593
1157951006407	RHS protein; Region: RHS; pfam03527
1157951006408	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951006409	Domain of unknown function (DUF1795); Region: DUF1795; cl02256
1157951006410	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1157951006411	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1157951006412	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1157951006413	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1157951006414	primosome assembly protein PriA; Validated; Region: PRK05580
1157951006415	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951006416	ATP binding site [chemical binding]; other site
1157951006417	putative Mg++ binding site [ion binding]; other site
1157951006418	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1157951006419	ATP-binding site [chemical binding]; other site
1157951006420	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1157951006421	Predicted integral membrane proteins containing uncharacterized repeats [Function unknown]; Region: COG5563
1157951006422	probable extracellular repeat, HAF family; Region: HAF_rpt; TIGR02913
1157951006423	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1157951006424	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1157951006425	dimerization interface [polypeptide binding]; other site
1157951006426	DNA binding site [nucleotide binding]
1157951006427	corepressor binding sites; other site
1157951006428	cystathionine gamma-synthase; Provisional; Region: PRK08045
1157951006429	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1157951006430	homodimer interface [polypeptide binding]; other site
1157951006431	substrate-cofactor binding pocket; other site
1157951006432	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951006433	catalytic residue [active]
1157951006434	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1157951006435	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1157951006436	putative catalytic residues [active]
1157951006437	putative nucleotide binding site [chemical binding]; other site
1157951006438	putative aspartate binding site [chemical binding]; other site
1157951006439	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1157951006440	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1157951006441	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1157951006442	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1157951006443	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1157951006444	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1157951006445	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1157951006446	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
1157951006447	Repair protein; Region: Repair_PSII; pfam04536
1157951006448	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1157951006449	FAD binding site [chemical binding]; other site
1157951006450	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cl00246
1157951006451	acetylornithine deacetylase; Provisional; Region: PRK05111
1157951006452	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1157951006453	metal binding site [ion binding]; metal-binding site
1157951006454	putative dimer interface [polypeptide binding]; other site
1157951006455	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1157951006456	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1157951006457	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1157951006458	nucleotide binding site [chemical binding]; other site
1157951006459	N-acetyl-L-glutamate binding site [chemical binding]; other site
1157951006460	argininosuccinate synthase; Provisional; Region: PRK13820
1157951006461	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1157951006462	ANP binding site [chemical binding]; other site
1157951006463	Substrate Binding Site II [chemical binding]; other site
1157951006464	Substrate Binding Site I [chemical binding]; other site
1157951006465	argininosuccinate lyase; Provisional; Region: PRK04833
1157951006466	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1157951006467	active sites [active]
1157951006468	tetramer interface [polypeptide binding]; other site
1157951006469	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1157951006470	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951006471	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1157951006472	dimerization interface [polypeptide binding]; other site
1157951006473	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1157951006474	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951006475	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1157951006476	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1157951006477	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951006478	hypothetical protein; Provisional; Region: PRK11056
1157951006479	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1157951006480	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951006481	S-adenosylmethionine binding site [chemical binding]; other site
1157951006482	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1157951006483	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951006484	N-terminal plug; other site
1157951006485	ligand-binding site [chemical binding]; other site
1157951006486	glutamate racemase; Provisional; Region: PRK00865
1157951006487	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1157951006488	FAD binding domain; Region: FAD_binding_4; pfam01565
1157951006489	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1157951006490	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1157951006491	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1157951006492	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1157951006493	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1157951006494	pantothenate kinase; Provisional; Region: PRK05439
1157951006495	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1157951006496	ATP-binding site [chemical binding]; other site
1157951006497	CoA-binding site [chemical binding]; other site
1157951006498	Mg2+-binding site [ion binding]; other site
1157951006499	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1157951006500	G1 box; other site
1157951006501	GTP/Mg2+ binding site [chemical binding]; other site
1157951006502	G2 box; other site
1157951006503	Switch I region; other site
1157951006504	G3 box; other site
1157951006505	Switch II region; other site
1157951006506	G4 box; other site
1157951006507	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1157951006508	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1157951006509	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1157951006510	Antibiotic Binding Site [chemical binding]; other site
1157951006511	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1157951006512	classical (c) SDRs; Region: SDR_c; cd05233
1157951006513	NAD(P) binding site [chemical binding]; other site
1157951006514	active site
1157951006515	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; cl01093
1157951006516	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1157951006517	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1157951006518	heme binding site [chemical binding]; other site
1157951006519	ferroxidase pore; other site
1157951006520	ferroxidase diiron center [ion binding]; other site
1157951006521	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1157951006522	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1157951006523	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1157951006524	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1157951006525	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1157951006526	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1157951006527	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1157951006528	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1157951006529	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1157951006530	protein-rRNA interface [nucleotide binding]; other site
1157951006531	putative translocon binding site; other site
1157951006532	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1157951006533	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1157951006534	G-X-X-G motif; other site
1157951006535	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1157951006536	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1157951006537	23S rRNA interface [nucleotide binding]; other site
1157951006538	5S rRNA interface [nucleotide binding]; other site
1157951006539	putative antibiotic binding site [chemical binding]; other site
1157951006540	L25 interface [polypeptide binding]; other site
1157951006541	L27 interface [polypeptide binding]; other site
1157951006542	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1157951006543	23S rRNA interface [nucleotide binding]; other site
1157951006544	putative translocon interaction site; other site
1157951006545	signal recognition particle (SRP54) interaction site; other site
1157951006546	L23 interface [polypeptide binding]; other site
1157951006547	trigger factor interaction site; other site
1157951006548	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1157951006549	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1157951006550	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1157951006551	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1157951006552	RNA binding site [nucleotide binding]; other site
1157951006553	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1157951006554	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1157951006555	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1157951006556	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1157951006557	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1157951006558	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1157951006559	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1157951006560	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1157951006561	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1157951006562	5S rRNA interface [nucleotide binding]; other site
1157951006563	23S rRNA interface [nucleotide binding]; other site
1157951006564	L5 interface [polypeptide binding]; other site
1157951006565	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1157951006566	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1157951006567	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1157951006568	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1157951006569	23S rRNA binding site [nucleotide binding]; other site
1157951006570	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1157951006571	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1157951006572	SecY translocase; Region: SecY; pfam00344
1157951006573	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
1157951006574	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1157951006575	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1157951006576	30S ribosomal protein S11; Validated; Region: PRK05309
1157951006577	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1157951006578	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1157951006579	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1157951006580	RNA binding surface [nucleotide binding]; other site
1157951006581	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1157951006582	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1157951006583	alphaNTD homodimer interface [polypeptide binding]; other site
1157951006584	alphaNTD - beta interaction site [polypeptide binding]; other site
1157951006585	alphaNTD - beta' interaction site [polypeptide binding]; other site
1157951006586	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1157951006587	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1157951006588	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1157951006589	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1157951006590	DNA binding residues [nucleotide binding]
1157951006591	dimer interface [polypeptide binding]; other site
1157951006592	metal binding site [ion binding]; metal-binding site
1157951006593	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1157951006594	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1157951006595	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1157951006596	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1157951006597	TrkA-N domain; Region: TrkA_N; pfam02254
1157951006598	TrkA-C domain; Region: TrkA_C; pfam02080
1157951006599	TrkA-N domain; Region: TrkA_N; pfam02254
1157951006600	TrkA-C domain; Region: TrkA_C; pfam02080
1157951006601	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1157951006602	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1157951006603	putative RNA binding site [nucleotide binding]; other site
1157951006604	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951006605	S-adenosylmethionine binding site [chemical binding]; other site
1157951006606	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1157951006607	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1157951006608	putative active site [active]
1157951006609	substrate binding site [chemical binding]; other site
1157951006610	putative cosubstrate binding site; other site
1157951006611	catalytic site [active]
1157951006612	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1157951006613	substrate binding site [chemical binding]; other site
1157951006614	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1157951006615	active site
1157951006616	catalytic residues [active]
1157951006617	metal binding site [ion binding]; metal-binding site
1157951006618	hypothetical protein; Provisional; Region: PRK10736
1157951006619	DNA protecting protein DprA; Region: dprA; TIGR00732
1157951006620	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1157951006621	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1157951006622	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1157951006623	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1157951006624	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1157951006625	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1157951006626	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1157951006627	shikimate binding site; other site
1157951006628	NAD(P) binding site [chemical binding]; other site
1157951006629	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1157951006630	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1157951006631	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1157951006632	trimer interface [polypeptide binding]; other site
1157951006633	putative metal binding site [ion binding]; other site
1157951006634	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1157951006635	transcriptional regulator HdfR; Provisional; Region: PRK03601
1157951006636	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951006637	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1157951006638	dimerization interface [polypeptide binding]; other site
1157951006639	hypothetical protein; Provisional; Region: PRK11027
1157951006640	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1157951006641	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1157951006642	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1157951006643	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1157951006644	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1157951006645	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1157951006646	PYR/PP interface [polypeptide binding]; other site
1157951006647	dimer interface [polypeptide binding]; other site
1157951006648	TPP binding site [chemical binding]; other site
1157951006649	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951006650	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1157951006651	TPP-binding site [chemical binding]; other site
1157951006652	dimer interface [polypeptide binding]; other site
1157951006653	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1157951006654	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1157951006655	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1157951006656	homodimer interface [polypeptide binding]; other site
1157951006657	substrate-cofactor binding pocket; other site
1157951006658	catalytic residue [active]
1157951006659	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1157951006660	threonine dehydratase; Reviewed; Region: PRK09224
1157951006661	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1157951006662	tetramer interface [polypeptide binding]; other site
1157951006663	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951006664	catalytic residue [active]
1157951006665	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1157951006666	putative Ile/Val binding site [chemical binding]; other site
1157951006667	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1157951006668	putative Ile/Val binding site [chemical binding]; other site
1157951006669	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951006670	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1157951006671	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1157951006672	putative dimerization interface [polypeptide binding]; other site
1157951006673	ketol-acid reductoisomerase; Validated; Region: PRK05225
1157951006674	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1157951006675	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1157951006676	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1157951006677	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1157951006678	Part of AAA domain; Region: AAA_19; pfam13245
1157951006679	Family description; Region: UvrD_C_2; pfam13538
1157951006680	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1157951006681	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1157951006682	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1157951006683	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1157951006684	ATP binding site [chemical binding]; other site
1157951006685	Mg++ binding site [ion binding]; other site
1157951006686	motif III; other site
1157951006687	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951006688	nucleotide binding region [chemical binding]; other site
1157951006689	ATP-binding site [chemical binding]; other site
1157951006690	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1157951006691	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1157951006692	catalytic residues [active]
1157951006693	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1157951006694	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1157951006695	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1157951006696	RNA binding site [nucleotide binding]; other site
1157951006697	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1157951006698	multimer interface [polypeptide binding]; other site
1157951006699	Walker A motif; other site
1157951006700	ATP binding site [chemical binding]; other site
1157951006701	Walker B motif; other site
1157951006702	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
1157951006703	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1157951006704	Mg++ binding site [ion binding]; other site
1157951006705	putative catalytic motif [active]
1157951006706	substrate binding site [chemical binding]; other site
1157951006707	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1157951006708	Chain length determinant protein; Region: Wzz; cl15801
1157951006709	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1157951006710	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1157951006711	active site
1157951006712	homodimer interface [polypeptide binding]; other site
1157951006713	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1157951006714	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1157951006715	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1157951006716	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1157951006717	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1157951006718	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1157951006719	NAD binding site [chemical binding]; other site
1157951006720	substrate binding site [chemical binding]; other site
1157951006721	homodimer interface [polypeptide binding]; other site
1157951006722	active site
1157951006723	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1157951006724	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1157951006725	substrate binding site; other site
1157951006726	tetramer interface; other site
1157951006727	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1157951006728	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951006729	Coenzyme A binding pocket [chemical binding]; other site
1157951006730	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1157951006731	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1157951006732	inhibitor-cofactor binding pocket; inhibition site
1157951006733	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951006734	catalytic residue [active]
1157951006735	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1157951006736	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1157951006737	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1157951006738	putative common antigen polymerase; Provisional; Region: PRK02975
1157951006739	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1157951006740	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1157951006741	putative transport protein YifK; Provisional; Region: PRK10746
1157951006742	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1157951006743	HemY protein N-terminus; Region: HemY_N; pfam07219
1157951006744	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1157951006745	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1157951006746	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1157951006747	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1157951006748	active site
1157951006749	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1157951006750	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1157951006751	domain interfaces; other site
1157951006752	active site
1157951006753	adenylate cyclase; Provisional; Region: cyaA; PRK09450
1157951006754	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1157951006755	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1157951006756	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1157951006757	putative iron binding site [ion binding]; other site
1157951006758	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; cl02361
1157951006759	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1157951006760	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1157951006761	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1157951006762	hypothetical protein; Provisional; Region: PRK10963
1157951006763	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1157951006764	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951006765	active site
1157951006766	DNA binding site [nucleotide binding]
1157951006767	Int/Topo IB signature motif; other site
1157951006768	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1157951006769	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951006770	motif II; other site
1157951006771	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1157951006772	Part of AAA domain; Region: AAA_19; pfam13245
1157951006773	Family description; Region: UvrD_C_2; pfam13538
1157951006774	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
1157951006775	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1157951006776	RF-1 domain; Region: RF-1; cl17422
1157951006777	hypothetical protein; Reviewed; Region: PRK09588
1157951006778	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
1157951006779	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1157951006780	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1157951006781	active site
1157951006782	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1157951006783	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1157951006784	EamA-like transporter family; Region: EamA; pfam00892
1157951006785	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1157951006786	CoenzymeA binding site [chemical binding]; other site
1157951006787	subunit interaction site [polypeptide binding]; other site
1157951006788	PHB binding site; other site
1157951006789	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1157951006790	dimerization interface [polypeptide binding]; other site
1157951006791	substrate binding site [chemical binding]; other site
1157951006792	active site
1157951006793	calcium binding site [ion binding]; other site
1157951006794	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1157951006795	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951006796	ATP binding site [chemical binding]; other site
1157951006797	putative Mg++ binding site [ion binding]; other site
1157951006798	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951006799	nucleotide binding region [chemical binding]; other site
1157951006800	ATP-binding site [chemical binding]; other site
1157951006801	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1157951006802	HRDC domain; Region: HRDC; pfam00570
1157951006803	lysophospholipase L2; Provisional; Region: PRK10749
1157951006804	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1157951006805	putative hydrolase; Provisional; Region: PRK10976
1157951006806	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951006807	active site
1157951006808	motif I; other site
1157951006809	motif II; other site
1157951006810	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1157951006811	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951006812	Sel1-like repeats; Region: SEL1; smart00671
1157951006813	Sel1-like repeats; Region: SEL1; smart00671
1157951006814	Sel1-like repeats; Region: SEL1; smart00671
1157951006815	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1157951006816	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1157951006817	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1157951006818	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1157951006819	Predicted GTPases [General function prediction only]; Region: COG1162
1157951006820	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1157951006821	RNA binding site [nucleotide binding]; other site
1157951006822	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1157951006823	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1157951006824	GTP/Mg2+ binding site [chemical binding]; other site
1157951006825	G4 box; other site
1157951006826	G5 box; other site
1157951006827	G1 box; other site
1157951006828	Switch I region; other site
1157951006829	G2 box; other site
1157951006830	G3 box; other site
1157951006831	Switch II region; other site
1157951006832	GTPase RsgA; Reviewed; Region: PRK12288
1157951006833	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1157951006834	catalytic site [active]
1157951006835	putative active site [active]
1157951006836	putative substrate binding site [chemical binding]; other site
1157951006837	dimer interface [polypeptide binding]; other site
1157951006838	epoxyqueuosine reductase; Region: TIGR00276
1157951006839	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1157951006840	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
1157951006841	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1157951006842	AMIN domain; Region: AMIN; pfam11741
1157951006843	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1157951006844	active site
1157951006845	metal binding site [ion binding]; metal-binding site
1157951006846	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1157951006847	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951006848	ATP binding site [chemical binding]; other site
1157951006849	Mg2+ binding site [ion binding]; other site
1157951006850	G-X-G motif; other site
1157951006851	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1157951006852	ATP binding site [chemical binding]; other site
1157951006853	MutL C terminal dimerisation domain; Region: MutL_C; cl07336
1157951006854	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1157951006855	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1157951006856	bacterial Hfq-like; Region: Hfq; cd01716
1157951006857	hexamer interface [polypeptide binding]; other site
1157951006858	Sm1 motif; other site
1157951006859	RNA binding site [nucleotide binding]; other site
1157951006860	Sm2 motif; other site
1157951006861	GTPase HflX; Provisional; Region: PRK11058
1157951006862	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1157951006863	HflX GTPase family; Region: HflX; cd01878
1157951006864	G1 box; other site
1157951006865	GTP/Mg2+ binding site [chemical binding]; other site
1157951006866	Switch I region; other site
1157951006867	G2 box; other site
1157951006868	G3 box; other site
1157951006869	Switch II region; other site
1157951006870	G4 box; other site
1157951006871	G5 box; other site
1157951006872	FtsH protease regulator HflK; Provisional; Region: PRK10930
1157951006873	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1157951006874	FtsH protease regulator HflC; Provisional; Region: PRK11029
1157951006875	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1157951006876	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1157951006877	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1157951006878	GDP-binding site [chemical binding]; other site
1157951006879	ACT binding site; other site
1157951006880	IMP binding site; other site
1157951006881	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1157951006882	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1157951006883	transcriptional repressor NsrR; Provisional; Region: PRK11014
1157951006884	Rrf2 family protein; Region: rrf2_super; TIGR00738
1157951006885	exoribonuclease R; Provisional; Region: PRK11642
1157951006886	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1157951006887	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1157951006888	RNB domain; Region: RNB; pfam00773
1157951006889	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1157951006890	RNA binding site [nucleotide binding]; other site
1157951006891	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1157951006892	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1157951006893	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1157951006894	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1157951006895	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1157951006896	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1157951006897	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1157951006898	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1157951006899	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1157951006900	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1157951006901	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1157951006902	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1157951006903	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1157951006904	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1157951006905	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1157951006906	active site
1157951006907	malate:quinone oxidoreductase; Validated; Region: PRK05257
1157951006908	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1157951006909	Cupin domain; Region: Cupin_2; pfam07883
1157951006910	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1157951006911	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1157951006912	dimer interface [polypeptide binding]; other site
1157951006913	ADP-ribose binding site [chemical binding]; other site
1157951006914	active site
1157951006915	nudix motif; other site
1157951006916	metal binding site [ion binding]; metal-binding site
1157951006917	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1157951006918	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1157951006919	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951006920	active site
1157951006921	phosphorylation site [posttranslational modification]
1157951006922	intermolecular recognition site; other site
1157951006923	dimerization interface [polypeptide binding]; other site
1157951006924	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951006925	DNA binding site [nucleotide binding]
1157951006926	sensor protein QseC; Provisional; Region: PRK10337
1157951006927	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951006928	dimer interface [polypeptide binding]; other site
1157951006929	phosphorylation site [posttranslational modification]
1157951006930	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951006931	ATP binding site [chemical binding]; other site
1157951006932	Mg2+ binding site [ion binding]; other site
1157951006933	G-X-G motif; other site
1157951006934	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
1157951006935	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1157951006936	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1157951006937	Domain of unknown function DUF21; Region: DUF21; pfam01595
1157951006938	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1157951006939	Transporter associated domain; Region: CorC_HlyC; smart01091
1157951006940	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1157951006941	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1157951006942	Surface antigen; Region: Bac_surface_Ag; pfam01103
1157951006943	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1157951006944	Family of unknown function (DUF490); Region: DUF490; pfam04357
1157951006945	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1157951006946	putative active site pocket [active]
1157951006947	dimerization interface [polypeptide binding]; other site
1157951006948	putative catalytic residue [active]
1157951006949	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1157951006950	dimer interface [polypeptide binding]; other site
1157951006951	substrate binding site [chemical binding]; other site
1157951006952	metal binding sites [ion binding]; metal-binding site
1157951006953	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1157951006954	AMP binding site [chemical binding]; other site
1157951006955	metal binding site [ion binding]; metal-binding site
1157951006956	active site
1157951006957	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1157951006958	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1157951006959	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1157951006960	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1157951006961	arginine repressor; Provisional; Region: PRK05066
1157951006962	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1157951006963	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1157951006964	malate dehydrogenase; Provisional; Region: PRK05086
1157951006965	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1157951006966	NAD binding site [chemical binding]; other site
1157951006967	dimerization interface [polypeptide binding]; other site
1157951006968	Substrate binding site [chemical binding]; other site
1157951006969	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
1157951006970	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1157951006971	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1157951006972	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1157951006973	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1157951006974	substrate binding pocket [chemical binding]; other site
1157951006975	chain length determination region; other site
1157951006976	substrate-Mg2+ binding site; other site
1157951006977	catalytic residues [active]
1157951006978	aspartate-rich region 1; other site
1157951006979	active site lid residues [active]
1157951006980	aspartate-rich region 2; other site
1157951006981	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1157951006982	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1157951006983	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1157951006984	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1157951006985	GTP1/OBG; Region: GTP1_OBG; pfam01018
1157951006986	Obg GTPase; Region: Obg; cd01898
1157951006987	G1 box; other site
1157951006988	GTP/Mg2+ binding site [chemical binding]; other site
1157951006989	Switch I region; other site
1157951006990	G2 box; other site
1157951006991	G3 box; other site
1157951006992	Switch II region; other site
1157951006993	G4 box; other site
1157951006994	G5 box; other site
1157951006995	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1157951006996	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1157951006997	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1157951006998	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1157951006999	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1157951007000	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; cl00663
1157951007001	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1157951007002	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951007003	S-adenosylmethionine binding site [chemical binding]; other site
1157951007004	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1157951007005	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951007006	Walker A motif; other site
1157951007007	ATP binding site [chemical binding]; other site
1157951007008	Walker B motif; other site
1157951007009	arginine finger; other site
1157951007010	Peptidase family M41; Region: Peptidase_M41; pfam01434
1157951007011	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1157951007012	dihydropteroate synthase; Region: DHPS; TIGR01496
1157951007013	substrate binding pocket [chemical binding]; other site
1157951007014	dimer interface [polypeptide binding]; other site
1157951007015	inhibitor binding site; inhibition site
1157951007016	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1157951007017	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1157951007018	active site
1157951007019	substrate binding site [chemical binding]; other site
1157951007020	metal binding site [ion binding]; metal-binding site
1157951007021	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1157951007022	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1157951007023	Sm and related proteins; Region: Sm_like; cl00259
1157951007024	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1157951007025	putative oligomer interface [polypeptide binding]; other site
1157951007026	putative RNA binding site [nucleotide binding]; other site
1157951007027	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1157951007028	NusA N-terminal domain; Region: NusA_N; pfam08529
1157951007029	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1157951007030	RNA binding site [nucleotide binding]; other site
1157951007031	homodimer interface [polypeptide binding]; other site
1157951007032	NusA-like KH domain; Region: KH_5; pfam13184
1157951007033	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1157951007034	G-X-X-G motif; other site
1157951007035	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1157951007036	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1157951007037	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1157951007038	translation initiation factor IF-2; Region: IF-2; TIGR00487
1157951007039	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1157951007040	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1157951007041	G1 box; other site
1157951007042	putative GEF interaction site [polypeptide binding]; other site
1157951007043	GTP/Mg2+ binding site [chemical binding]; other site
1157951007044	Switch I region; other site
1157951007045	G2 box; other site
1157951007046	G3 box; other site
1157951007047	Switch II region; other site
1157951007048	G4 box; other site
1157951007049	G5 box; other site
1157951007050	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1157951007051	Translation-initiation factor 2; Region: IF-2; pfam11987
1157951007052	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1157951007053	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1157951007054	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1157951007055	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1157951007056	RNA binding site [nucleotide binding]; other site
1157951007057	active site
1157951007058	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1157951007059	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1157951007060	16S/18S rRNA binding site [nucleotide binding]; other site
1157951007061	S13e-L30e interaction site [polypeptide binding]; other site
1157951007062	25S rRNA binding site [nucleotide binding]; other site
1157951007063	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1157951007064	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1157951007065	RNase E interface [polypeptide binding]; other site
1157951007066	trimer interface [polypeptide binding]; other site
1157951007067	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1157951007068	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1157951007069	RNase E interface [polypeptide binding]; other site
1157951007070	trimer interface [polypeptide binding]; other site
1157951007071	active site
1157951007072	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1157951007073	putative nucleic acid binding region [nucleotide binding]; other site
1157951007074	G-X-X-G motif; other site
1157951007075	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1157951007076	RNA binding site [nucleotide binding]; other site
1157951007077	domain interface; other site
1157951007078	lipoprotein NlpI; Provisional; Region: PRK11189
1157951007079	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1157951007080	binding surface
1157951007081	TPR motif; other site
1157951007082	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1157951007083	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1157951007084	ATP binding site [chemical binding]; other site
1157951007085	Mg++ binding site [ion binding]; other site
1157951007086	motif III; other site
1157951007087	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951007088	nucleotide binding region [chemical binding]; other site
1157951007089	ATP-binding site [chemical binding]; other site
1157951007090	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1157951007091	putative RNA binding site [nucleotide binding]; other site
1157951007092	hypothetical protein; Provisional; Region: PRK10039
1157951007093	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1157951007094	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951007095	active site
1157951007096	phosphorylation site [posttranslational modification]
1157951007097	intermolecular recognition site; other site
1157951007098	dimerization interface [polypeptide binding]; other site
1157951007099	LytTr DNA-binding domain; Region: LytTR; pfam04397
1157951007100	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1157951007101	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1157951007102	GAF domain; Region: GAF_3; pfam13492
1157951007103	Histidine kinase; Region: His_kinase; pfam06580
1157951007104	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951007105	ATP binding site [chemical binding]; other site
1157951007106	Mg2+ binding site [ion binding]; other site
1157951007107	G-X-G motif; other site
1157951007108	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951007109	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1157951007110	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951007111	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1157951007112	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1157951007113	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1157951007114	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1157951007115	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1157951007116	Predicted membrane protein [Function unknown]; Region: COG3766
1157951007117	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1157951007118	Protein of unknown function (DUF1190); Region: DUF1190; cl10031
1157951007119	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1157951007120	putative protease; Provisional; Region: PRK15447
1157951007121	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1157951007122	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1157951007123	Peptidase family U32; Region: Peptidase_U32; pfam01136
1157951007124	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1157951007125	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1157951007126	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951007127	Coenzyme A binding pocket [chemical binding]; other site
1157951007128	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1157951007129	GIY-YIG motif/motif A; other site
1157951007130	putative active site [active]
1157951007131	putative metal binding site [ion binding]; other site
1157951007132	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1157951007133	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3787; cl17897
1157951007134	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; PRK11121
1157951007135	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1157951007136	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1157951007137	ATP cone domain; Region: ATP-cone; pfam03477
1157951007138	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1157951007139	effector binding site; other site
1157951007140	active site
1157951007141	Zn binding site [ion binding]; other site
1157951007142	glycine loop; other site
1157951007143	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007144	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007145	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1157951007146	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951007147	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951007148	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951007149	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951007150	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951007151	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951007152	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007153	Fimbrial protein; Region: Fimbrial; pfam00419
1157951007154	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1157951007155	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951007156	Coenzyme A binding pocket [chemical binding]; other site
1157951007157	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1157951007158	homotrimer interaction site [polypeptide binding]; other site
1157951007159	putative active site [active]
1157951007160	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1157951007161	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1157951007162	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1157951007163	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1157951007164	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1157951007165	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1157951007166	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1157951007167	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1157951007168	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951007169	DNA binding site [nucleotide binding]
1157951007170	domain linker motif; other site
1157951007171	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1157951007172	dimerization interface [polypeptide binding]; other site
1157951007173	ligand binding site [chemical binding]; other site
1157951007174	nucleoside transporter; Region: 2A0110; TIGR00889
1157951007175	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
1157951007176	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1157951007177	NAD binding site [chemical binding]; other site
1157951007178	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1157951007179	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1157951007180	active site
1157951007181	metal binding site [ion binding]; metal-binding site
1157951007182	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1157951007183	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1157951007184	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1157951007185	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1157951007186	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1157951007187	RNase E inhibitor protein; Provisional; Region: PRK11191
1157951007188	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
1157951007189	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
1157951007190	metal-binding site [ion binding]
1157951007191	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
1157951007192	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1157951007193	DNA binding residues [nucleotide binding]
1157951007194	dimer interface [polypeptide binding]; other site
1157951007195	copper binding site [ion binding]; other site
1157951007196	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1157951007197	catalytic residues [active]
1157951007198	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1157951007199	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1157951007200	metal-binding site [ion binding]
1157951007201	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1157951007202	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1157951007203	metal-binding site [ion binding]
1157951007204	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1157951007205	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951007206	motif II; other site
1157951007207	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1157951007208	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1157951007209	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951007210	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951007211	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1157951007212	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951007213	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951007214	Cd(II)/Pb(II)-responsive transcriptional regulator; Region: CadR-PbrR; TIGR02047
1157951007215	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1157951007216	DNA binding residues [nucleotide binding]
1157951007217	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951007218	Coenzyme A binding pocket [chemical binding]; other site
1157951007219	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1157951007220	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1157951007221	HIGH motif; other site
1157951007222	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1157951007223	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1157951007224	active site
1157951007225	KMSKS motif; other site
1157951007226	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1157951007227	tRNA binding surface [nucleotide binding]; other site
1157951007228	anticodon binding site; other site
1157951007229	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1157951007230	DNA polymerase III subunit chi; Validated; Region: PRK05728
1157951007231	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1157951007232	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1157951007233	interface (dimer of trimers) [polypeptide binding]; other site
1157951007234	Substrate-binding/catalytic site; other site
1157951007235	Zn-binding sites [ion binding]; other site
1157951007236	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1157951007237	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1157951007238	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1157951007239	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1157951007240	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1157951007241	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1157951007242	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1157951007243	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1157951007244	active site
1157951007245	Int/Topo IB signature motif; other site
1157951007246	Antirestriction protein (ArdA); Region: ArdA; pfam07275
1157951007247	Restriction endonuclease [Defense mechanisms]; Region: COG3587
1157951007248	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951007249	ATP binding site [chemical binding]; other site
1157951007250	putative Mg++ binding site [ion binding]; other site
1157951007251	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1157951007252	DNA methylase; Region: N6_N4_Mtase; pfam01555
1157951007253	DNA methylase; Region: N6_N4_Mtase; cl17433
1157951007254	Domain of unknown function (DUF4391); Region: DUF4391; pfam14335
1157951007255	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_c; cd10311
1157951007256	putative active site [active]
1157951007257	catalytic site [active]
1157951007258	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
1157951007259	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951007260	ATP binding site [chemical binding]; other site
1157951007261	putative Mg++ binding site [ion binding]; other site
1157951007262	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951007263	nucleotide binding region [chemical binding]; other site
1157951007264	ATP-binding site [chemical binding]; other site
1157951007265	Predicted transcriptional regulator [Transcription]; Region: COG2378
1157951007266	WYL domain; Region: WYL; pfam13280
1157951007267	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
1157951007268	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1157951007269	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1157951007270	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1157951007271	Transposase; Region: HTH_Tnp_1; pfam01527
1157951007272	HTH-like domain; Region: HTH_21; pfam13276
1157951007273	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1157951007274	Integrase core domain; Region: rve; pfam00665
1157951007275	Integrase core domain; Region: rve_3; pfam13683
1157951007276	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1157951007277	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951007278	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951007279	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951007280	non-specific DNA binding site [nucleotide binding]; other site
1157951007281	salt bridge; other site
1157951007282	sequence-specific DNA binding site [nucleotide binding]; other site
1157951007283	Fimbrial protein; Region: Fimbrial; cl01416
1157951007284	Fimbrial protein; Region: Fimbrial; cl01416
1157951007285	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951007286	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951007287	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951007288	outer membrane usher protein; Provisional; Region: PRK15193
1157951007289	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951007290	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951007291	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951007292	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007293	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007294	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
1157951007295	mannosyl binding site [chemical binding]; other site
1157951007296	Fimbrial protein; Region: Fimbrial; pfam00419
1157951007297	Siderophore-interacting protein; Region: SIP; pfam04954
1157951007298	Transposase; Region: HTH_Tnp_1; cl17663
1157951007299	'potential frameshift: common BLAST hit: gi|332140571|ref|YP_004426309.1| Integrase, catalytic region'
1157951007300	Part of AAA domain; Region: AAA_19; pfam13245
1157951007301	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1157951007302	AAA domain; Region: AAA_12; pfam13087
1157951007303	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1157951007304	putative active site [active]
1157951007305	catalytic site [active]
1157951007306	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1157951007307	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1157951007308	active site
1157951007309	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
1157951007310	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
1157951007311	active site
1157951007312	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1157951007313	HutD; Region: HutD; pfam05962
1157951007314	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
1157951007315	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1157951007316	putative acyl-acceptor binding pocket; other site
1157951007317	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1157951007318	putative chaperone; Provisional; Region: PRK11678
1157951007319	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1157951007320	nucleotide binding site [chemical binding]; other site
1157951007321	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1157951007322	SBD interface [polypeptide binding]; other site
1157951007323	CAAX protease self-immunity; Region: Abi; pfam02517
1157951007324	MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. The domain is presumed to bind molybdopterin; Region: MoCF_BD; cl00451
1157951007325	hypothetical protein; Provisional; Region: PRK03673
1157951007326	MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. The domain is presumed to bind molybdopterin; Region: MoCF_BD; cl00451
1157951007327	MPT binding site; other site
1157951007328	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951007329	cell division protein DamX; Validated; Region: PRK10905
1157951007330	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1157951007331	catalytic residues [active]
1157951007332	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
1157951007333	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1157951007334	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
1157951007335	putative ligand binding residues [chemical binding]; other site
1157951007336	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1157951007337	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951007338	ABC-ATPase subunit  interface; other site
1157951007339	dimer interface [polypeptide binding]; other site
1157951007340	putative PBP binding regions; other site
1157951007341	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951007342	ABC-ATPase subunit  interface; other site
1157951007343	dimer interface [polypeptide binding]; other site
1157951007344	putative PBP binding regions; other site
1157951007345	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1157951007346	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1157951007347	Walker A/P-loop; other site
1157951007348	ATP binding site [chemical binding]; other site
1157951007349	Q-loop/lid; other site
1157951007350	ABC transporter signature motif; other site
1157951007351	Walker B; other site
1157951007352	D-loop; other site
1157951007353	H-loop/switch region; other site
1157951007354	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1157951007355	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1157951007356	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951007357	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951007358	non-specific DNA binding site [nucleotide binding]; other site
1157951007359	salt bridge; other site
1157951007360	sequence-specific DNA binding site [nucleotide binding]; other site
1157951007361	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
1157951007362	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1157951007363	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1157951007364	peptide binding site [polypeptide binding]; other site
1157951007365	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1157951007366	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951007367	dimer interface [polypeptide binding]; other site
1157951007368	conserved gate region; other site
1157951007369	putative PBP binding loops; other site
1157951007370	ABC-ATPase subunit interface; other site
1157951007371	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1157951007372	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951007373	dimer interface [polypeptide binding]; other site
1157951007374	conserved gate region; other site
1157951007375	putative PBP binding loops; other site
1157951007376	ABC-ATPase subunit interface; other site
1157951007377	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1157951007378	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1157951007379	Walker A/P-loop; other site
1157951007380	ATP binding site [chemical binding]; other site
1157951007381	Q-loop/lid; other site
1157951007382	ABC transporter signature motif; other site
1157951007383	Walker B; other site
1157951007384	D-loop; other site
1157951007385	H-loop/switch region; other site
1157951007386	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1157951007387	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1157951007388	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1157951007389	Walker A/P-loop; other site
1157951007390	ATP binding site [chemical binding]; other site
1157951007391	Q-loop/lid; other site
1157951007392	ABC transporter signature motif; other site
1157951007393	Walker B; other site
1157951007394	D-loop; other site
1157951007395	H-loop/switch region; other site
1157951007396	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1157951007397	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951007398	DNA-binding site [nucleotide binding]; DNA binding site
1157951007399	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1157951007400	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1157951007401	M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657
1157951007402	putative oligomer interface [polypeptide binding]; other site
1157951007403	putative active site [active]
1157951007404	metal binding site [ion binding]; metal-binding site
1157951007405	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1157951007406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951007407	putative substrate translocation pore; other site
1157951007408	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1157951007409	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1157951007410	putative [Fe4-S4] binding site [ion binding]; other site
1157951007411	putative molybdopterin cofactor binding site [chemical binding]; other site
1157951007412	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1157951007413	putative molybdopterin cofactor binding site; other site
1157951007414	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1157951007415	4Fe-4S binding domain; Region: Fer4; pfam00037
1157951007416	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1157951007417	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1157951007418	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1157951007419	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951007420	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951007421	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951007422	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1157951007423	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_7; cd07585
1157951007424	putative active site [active]
1157951007425	catalytic triad [active]
1157951007426	putative dimer interface [polypeptide binding]; other site
1157951007427	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951007428	non-specific DNA binding site [nucleotide binding]; other site
1157951007429	salt bridge; other site
1157951007430	sequence-specific DNA binding site [nucleotide binding]; other site
1157951007431	Fimbrial protein; Region: Fimbrial; cl01416
1157951007432	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951007433	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951007434	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951007435	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951007436	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951007437	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951007438	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951007439	Fimbrial protein; Region: Fimbrial; cl01416
1157951007440	Fimbrial protein; Region: Fimbrial; pfam00419
1157951007441	fumarate hydratase; Provisional; Region: PRK15389
1157951007442	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1157951007443	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1157951007444	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1157951007445	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1157951007446	Walker A/P-loop; other site
1157951007447	ATP binding site [chemical binding]; other site
1157951007448	Q-loop/lid; other site
1157951007449	ABC transporter signature motif; other site
1157951007450	Walker B; other site
1157951007451	D-loop; other site
1157951007452	H-loop/switch region; other site
1157951007453	TOBE domain; Region: TOBE_2; pfam08402
1157951007454	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1157951007455	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951007456	dimer interface [polypeptide binding]; other site
1157951007457	conserved gate region; other site
1157951007458	putative PBP binding loops; other site
1157951007459	ABC-ATPase subunit interface; other site
1157951007460	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1157951007461	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951007462	dimer interface [polypeptide binding]; other site
1157951007463	conserved gate region; other site
1157951007464	putative PBP binding loops; other site
1157951007465	ABC-ATPase subunit interface; other site
1157951007466	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1157951007467	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1157951007468	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1157951007469	Predicted flavoprotein [General function prediction only]; Region: COG0431
1157951007470	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1157951007471	dimer interface [polypeptide binding]; other site
1157951007472	putative tRNA-binding site [nucleotide binding]; other site
1157951007473	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1157951007474	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951007475	hypothetical protein; Provisional; Region: PRK10203
1157951007476	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
1157951007477	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1157951007478	Pirin-related protein [General function prediction only]; Region: COG1741
1157951007479	Pirin; Region: Pirin; pfam02678
1157951007480	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1157951007481	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951007482	Coenzyme A binding pocket [chemical binding]; other site
1157951007483	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
1157951007484	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
1157951007485	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1157951007486	Transposase; Region: HTH_Tnp_1; cl17663
1157951007487	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1157951007488	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1157951007489	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1157951007490	MPN+ (JAMM) motif; other site
1157951007491	Zinc-binding site [ion binding]; other site
1157951007492	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1157951007493	Antirestriction protein; Region: Antirestrict; pfam03230
1157951007494	Antirestriction protein; Region: Antirestrict; pfam03230
1157951007495	Predicted GTPase [General function prediction only]; Region: COG3596
1157951007496	YfjP GTPase; Region: YfjP; cd11383
1157951007497	G1 box; other site
1157951007498	GTP/Mg2+ binding site [chemical binding]; other site
1157951007499	Switch I region; other site
1157951007500	G2 box; other site
1157951007501	Switch II region; other site
1157951007502	G3 box; other site
1157951007503	G4 box; other site
1157951007504	G5 box; other site
1157951007505	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1157951007506	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1157951007507	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1157951007508	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1157951007509	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1157951007510	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
1157951007511	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1157951007512	Helix-turn-helix domain; Region: HTH_38; pfam13936
1157951007513	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1157951007514	Integrase core domain; Region: rve; pfam00665
1157951007515	transposase/IS protein; Provisional; Region: PRK09183
1157951007516	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951007517	Walker A motif; other site
1157951007518	ATP binding site [chemical binding]; other site
1157951007519	Walker B motif; other site
1157951007520	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1157951007521	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1157951007522	putative transposase OrfB; Reviewed; Region: PHA02517
1157951007523	HTH-like domain; Region: HTH_21; pfam13276
1157951007524	Integrase core domain; Region: rve; pfam00665
1157951007525	Integrase core domain; Region: rve_2; pfam13333
1157951007526	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1157951007527	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951007528	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951007529	non-specific DNA binding site [nucleotide binding]; other site
1157951007530	salt bridge; other site
1157951007531	sequence-specific DNA binding site [nucleotide binding]; other site
1157951007532	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007533	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007534	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1157951007535	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951007536	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951007537	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951007538	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1157951007539	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951007540	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951007541	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007542	Fimbrial protein; Region: Fimbrial; pfam00419
1157951007543	Fimbrial protein; Region: Fimbrial; pfam00419
1157951007544	Fimbrial protein; Region: Fimbrial; cl01416
1157951007545	Fimbrial protein; Region: Fimbrial; pfam00419
1157951007546	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951007547	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
1157951007548	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
1157951007549	HdeA/HdeB family; Region: HdeA; pfam06411
1157951007550	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1157951007551	nucleoside/Zn binding site; other site
1157951007552	dimer interface [polypeptide binding]; other site
1157951007553	catalytic motif [active]
1157951007554	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1157951007555	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1157951007556	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1157951007557	transposase/IS protein; Provisional; Region: PRK09183
1157951007558	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951007559	Walker A motif; other site
1157951007560	ATP binding site [chemical binding]; other site
1157951007561	Walker B motif; other site
1157951007562	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
1157951007563	Integrase core domain; Region: rve; pfam00665
1157951007564	probable regulatory domain; Region: near_KaiC_dom; TIGR03879
1157951007565	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1157951007566	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
1157951007567	FGGY-family pentulose kinase; Region: 5C_CHO_kinase; TIGR01315
1157951007568	N- and C-terminal domain interface [polypeptide binding]; other site
1157951007569	active site
1157951007570	MgATP binding site [chemical binding]; other site
1157951007571	catalytic site [active]
1157951007572	metal binding site [ion binding]; metal-binding site
1157951007573	carbohydrate binding site [chemical binding]; other site
1157951007574	putative homodimer interface [polypeptide binding]; other site
1157951007575	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1157951007576	classical (c) SDRs; Region: SDR_c; cd05233
1157951007577	NAD(P) binding site [chemical binding]; other site
1157951007578	active site
1157951007579	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1157951007580	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951007581	DNA binding site [nucleotide binding]
1157951007582	domain linker motif; other site
1157951007583	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1157951007584	dimerization interface [polypeptide binding]; other site
1157951007585	ligand binding site [chemical binding]; other site
1157951007586	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1157951007587	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1157951007588	Q-loop/lid; other site
1157951007589	ABC transporter signature motif; other site
1157951007590	Walker B; other site
1157951007591	D-loop; other site
1157951007592	H-loop/switch region; other site
1157951007593	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951007594	Walker A/P-loop; other site
1157951007595	ATP binding site [chemical binding]; other site
1157951007596	short chain dehydrogenase; Provisional; Region: PRK06841
1157951007597	classical (c) SDRs; Region: SDR_c; cd05233
1157951007598	NAD(P) binding site [chemical binding]; other site
1157951007599	active site
1157951007600	transketolase; Reviewed; Region: PRK12753
1157951007601	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1157951007602	TPP-binding site [chemical binding]; other site
1157951007603	dimer interface [polypeptide binding]; other site
1157951007604	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1157951007605	PYR/PP interface [polypeptide binding]; other site
1157951007606	dimer interface [polypeptide binding]; other site
1157951007607	TPP binding site [chemical binding]; other site
1157951007608	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1157951007609	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
1157951007610	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1157951007611	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH2; cd08256
1157951007612	putative NAD(P) binding site [chemical binding]; other site
1157951007613	catalytic Zn binding site [ion binding]; other site
1157951007614	structural Zn binding site [ion binding]; other site
1157951007615	polyol permease family; Region: 2A0118; TIGR00897
1157951007616	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951007617	putative substrate translocation pore; other site
1157951007618	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
1157951007619	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
1157951007620	DAK2 domain; Region: Dak2; pfam02734
1157951007621	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1157951007622	non-specific DNA interactions [nucleotide binding]; other site
1157951007623	helix_turn_helix, cAMP Regulatory protein; Region: HTH_CRP; smart00419
1157951007624	DNA binding site [nucleotide binding]
1157951007625	sequence specific DNA binding site [nucleotide binding]; other site
1157951007626	putative cAMP binding site [chemical binding]; other site
1157951007627	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1157951007628	chromosome condensation membrane protein; Provisional; Region: PRK14196
1157951007629	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1157951007630	MarR family; Region: MarR_2; pfam12802
1157951007631	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1157951007632	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1157951007633	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1157951007634	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1157951007635	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1157951007636	N- and C-terminal domain interface [polypeptide binding]; other site
1157951007637	D-xylulose kinase; Region: XylB; TIGR01312
1157951007638	active site
1157951007639	MgATP binding site [chemical binding]; other site
1157951007640	catalytic site [active]
1157951007641	metal binding site [ion binding]; metal-binding site
1157951007642	xylulose binding site [chemical binding]; other site
1157951007643	homodimer interface [polypeptide binding]; other site
1157951007644	polyol permease family; Region: 2A0118; TIGR00897
1157951007645	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951007646	putative substrate translocation pore; other site
1157951007647	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
1157951007648	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1157951007649	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
1157951007650	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951007651	non-specific DNA binding site [nucleotide binding]; other site
1157951007652	salt bridge; other site
1157951007653	sequence-specific DNA binding site [nucleotide binding]; other site
1157951007654	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1157951007655	G1 box; other site
1157951007656	G2 box; other site
1157951007657	Switch I region; other site
1157951007658	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1157951007659	Transposase domain (DUF772); Region: DUF772; pfam05598
1157951007660	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
1157951007661	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1157951007662	AAA domain; Region: AAA_11; pfam13086
1157951007663	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951007664	ATP binding site [chemical binding]; other site
1157951007665	AAA domain; Region: AAA_12; pfam13087
1157951007666	Protein of unknown function DUF262; Region: DUF262; pfam03235
1157951007667	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1157951007668	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1157951007669	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1157951007670	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1157951007671	Integrase core domain; Region: rve_3; pfam13683
1157951007672	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951007673	non-specific DNA binding site [nucleotide binding]; other site
1157951007674	salt bridge; other site
1157951007675	sequence-specific DNA binding site [nucleotide binding]; other site
1157951007676	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1157951007677	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; cl04524
1157951007678	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951007679	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
1157951007680	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951007681	Walker A motif; other site
1157951007682	ATP binding site [chemical binding]; other site
1157951007683	Walker B motif; other site
1157951007684	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
1157951007685	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1157951007686	Antirestriction protein (ArdA); Region: ArdA; pfam07275
1157951007687	integrase; Provisional; Region: PRK09692
1157951007688	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1157951007689	active site
1157951007690	Int/Topo IB signature motif; other site
1157951007691	putative transcriptional regulator; Provisional; Region: PRK11640
1157951007692	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1157951007693	Glycerate kinase family; Region: Gly_kinase; cl00841
1157951007694	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1157951007695	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1157951007696	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1157951007697	Aspartase; Region: Aspartase; cd01357
1157951007698	active sites [active]
1157951007699	tetramer interface [polypeptide binding]; other site
1157951007700	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1157951007701	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1157951007702	oligomerisation interface [polypeptide binding]; other site
1157951007703	mobile loop; other site
1157951007704	roof hairpin; other site
1157951007705	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1157951007706	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1157951007707	ring oligomerisation interface [polypeptide binding]; other site
1157951007708	ATP/Mg binding site [chemical binding]; other site
1157951007709	stacking interactions; other site
1157951007710	hinge regions; other site
1157951007711	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1157951007712	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1157951007713	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951007714	FeS/SAM binding site; other site
1157951007715	elongation factor P; Validated; Region: PRK00529
1157951007716	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1157951007717	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1157951007718	RNA binding site [nucleotide binding]; other site
1157951007719	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1157951007720	RNA binding site [nucleotide binding]; other site
1157951007721	Uncharacterized small protein [Function unknown]; Region: COG2879
1157951007722	carbon starvation protein A; Provisional; Region: PRK15015
1157951007723	Carbon starvation protein CstA; Region: CstA; pfam02554
1157951007724	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1157951007725	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1157951007726	EamA-like transporter family; Region: EamA; pfam00892
1157951007727	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1157951007728	phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338
1157951007729	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951007730	DNA-binding site [nucleotide binding]; DNA binding site
1157951007731	FCD domain; Region: FCD; pfam07729
1157951007732	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1157951007733	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1157951007734	active site pocket [active]
1157951007735	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951007736	D-galactonate transporter; Region: 2A0114; TIGR00893
1157951007737	putative substrate translocation pore; other site
1157951007738	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1157951007739	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1157951007740	Iron-sulfur protein interface; other site
1157951007741	proximal quinone binding site [chemical binding]; other site
1157951007742	C-subunit interface; other site
1157951007743	distal quinone binding site; other site
1157951007744	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1157951007745	D-subunit interface [polypeptide binding]; other site
1157951007746	Iron-sulfur protein interface; other site
1157951007747	proximal quinone binding site [chemical binding]; other site
1157951007748	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1157951007749	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1157951007750	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1157951007751	L-aspartate oxidase; Provisional; Region: PRK06175
1157951007752	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1157951007753	poxB regulator PoxA; Provisional; Region: PRK09350
1157951007754	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1157951007755	motif 1; other site
1157951007756	dimer interface [polypeptide binding]; other site
1157951007757	active site
1157951007758	motif 2; other site
1157951007759	motif 3; other site
1157951007760	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1157951007761	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1157951007762	active site
1157951007763	catalytic site [active]
1157951007764	metal binding site [ion binding]; metal-binding site
1157951007765	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951007766	putative substrate translocation pore; other site
1157951007767	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1157951007768	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1157951007769	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1157951007770	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1157951007771	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1157951007772	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1157951007773	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1157951007774	Cysteine-rich domain; Region: CCG; pfam02754
1157951007775	Cysteine-rich domain; Region: CCG; pfam02754
1157951007776	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1157951007777	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1157951007778	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
1157951007779	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
1157951007780	Dak1 domain; Region: Dak1; pfam02733
1157951007781	hypothetical protein; Provisional; Region: PRK11212
1157951007782	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1157951007783	CPxP  motif; other site
1157951007784	putative transposase; Provisional; Region: PRK09857
1157951007785	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1157951007786	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1157951007787	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1157951007788	metal-binding site [ion binding]
1157951007789	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1157951007790	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1157951007791	Predicted membrane protein [Function unknown]; Region: COG3714
1157951007792	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1157951007793	hypothetical protein; Provisional; Region: PRK10910
1157951007794	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1157951007795	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951007796	S-adenosylmethionine binding site [chemical binding]; other site
1157951007797	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
1157951007798	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1157951007799	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1157951007800	P loop; other site
1157951007801	GTP binding site [chemical binding]; other site
1157951007802	cell division protein FtsE; Provisional; Region: PRK10908
1157951007803	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951007804	Walker A/P-loop; other site
1157951007805	ATP binding site [chemical binding]; other site
1157951007806	Q-loop/lid; other site
1157951007807	ABC transporter signature motif; other site
1157951007808	Walker B; other site
1157951007809	D-loop; other site
1157951007810	H-loop/switch region; other site
1157951007811	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1157951007812	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1157951007813	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1157951007814	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1157951007815	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1157951007816	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1157951007817	DNA binding residues [nucleotide binding]
1157951007818	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1157951007819	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1157951007820	putative metal binding site [ion binding]; other site
1157951007821	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1157951007822	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1157951007823	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1157951007824	dimerization interface [polypeptide binding]; other site
1157951007825	ligand binding site [chemical binding]; other site
1157951007826	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1157951007827	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1157951007828	TM-ABC transporter signature motif; other site
1157951007829	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1157951007830	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1157951007831	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1157951007832	TM-ABC transporter signature motif; other site
1157951007833	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1157951007834	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1157951007835	Walker A/P-loop; other site
1157951007836	ATP binding site [chemical binding]; other site
1157951007837	Q-loop/lid; other site
1157951007838	ABC transporter signature motif; other site
1157951007839	Walker B; other site
1157951007840	D-loop; other site
1157951007841	H-loop/switch region; other site
1157951007842	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951007843	Walker A/P-loop; other site
1157951007844	ATP binding site [chemical binding]; other site
1157951007845	Q-loop/lid; other site
1157951007846	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951007847	ABC transporter signature motif; other site
1157951007848	Walker B; other site
1157951007849	D-loop; other site
1157951007850	H-loop/switch region; other site
1157951007851	urocanate hydratase; Provisional; Region: PRK05414
1157951007852	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
1157951007853	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1157951007854	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1157951007855	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1157951007856	active site
1157951007857	Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]; Region: CodB; COG1457
1157951007858	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1157951007859	Na binding site [ion binding]; other site
1157951007860	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1157951007861	Ligand binding site [chemical binding]; other site
1157951007862	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1157951007863	electron transfer flavoprotein subunit alpha; Provisional; Region: PLN00022
1157951007864	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1157951007865	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1157951007866	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
1157951007867	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1157951007868	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
1157951007869	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1157951007870	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
1157951007871	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951007872	DNA-binding site [nucleotide binding]; DNA binding site
1157951007873	UTRA domain; Region: UTRA; pfam07702
1157951007874	tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; Region: tnaA; PRK13238
1157951007875	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
1157951007876	substrate binding site [chemical binding]; other site
1157951007877	tetramer interface [polypeptide binding]; other site
1157951007878	catalytic residue [active]
1157951007879	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
1157951007880	aromatic amino acid transport protein; Region: araaP; TIGR00837
1157951007881	Helix-turn-helix domain; Region: HTH_28; pfam13518
1157951007882	Winged helix-turn helix; Region: HTH_29; pfam13551
1157951007883	Homeodomain-like domain; Region: HTH_32; pfam13565
1157951007884	Integrase core domain; Region: rve; pfam00665
1157951007885	Integrase core domain; Region: rve_3; pfam13683
1157951007886	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
1157951007887	active site flap/lid [active]
1157951007888	nucleophilic elbow; other site
1157951007889	catalytic triad [active]
1157951007890	Domain of unknown function (DUF4123); Region: DUF4123; pfam13503
1157951007891	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1157951007892	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1157951007893	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1157951007894	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733
1157951007895	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1157951007896	YfjP GTPase; Region: YfjP; cd11383
1157951007897	G1 box; other site
1157951007898	GTP/Mg2+ binding site [chemical binding]; other site
1157951007899	Switch I region; other site
1157951007900	G2 box; other site
1157951007901	Switch II region; other site
1157951007902	G3 box; other site
1157951007903	G4 box; other site
1157951007904	G5 box; other site
1157951007905	Antirestriction protein; Region: Antirestrict; pfam03230
1157951007906	HTH domain; Region: HTH_11; cl17392
1157951007907	50S ribosomal protein L37Ae; Reviewed; Region: rpl37ae; PRK03976
1157951007908	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1157951007909	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1157951007910	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1157951007911	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1157951007912	FMN binding site [chemical binding]; other site
1157951007913	active site
1157951007914	catalytic residues [active]
1157951007915	substrate binding site [chemical binding]; other site
1157951007916	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1157951007917	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1157951007918	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1157951007919	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1157951007920	Na binding site [ion binding]; other site
1157951007921	hypothetical protein; Provisional; Region: PRK10633
1157951007922	Domain of unknown function (DUF202); Region: DUF202; cl09954
1157951007923	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1157951007924	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1157951007925	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1157951007926	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1157951007927	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1157951007928	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1157951007929	carboxyltransferase (CT) interaction site; other site
1157951007930	biotinylation site [posttranslational modification]; other site
1157951007931	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1157951007932	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1157951007933	active site
1157951007934	trimer interface [polypeptide binding]; other site
1157951007935	dimer interface [polypeptide binding]; other site
1157951007936	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1157951007937	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1157951007938	NADP binding site [chemical binding]; other site
1157951007939	dimer interface [polypeptide binding]; other site
1157951007940	rod shape-determining protein MreB; Provisional; Region: PRK13927
1157951007941	MreB and similar proteins; Region: MreB_like; cd10225
1157951007942	nucleotide binding site [chemical binding]; other site
1157951007943	Mg binding site [ion binding]; other site
1157951007944	putative protofilament interaction site [polypeptide binding]; other site
1157951007945	RodZ interaction site [polypeptide binding]; other site
1157951007946	rod shape-determining protein MreC; Region: mreC; TIGR00219
1157951007947	rod shape-determining protein MreC; Region: MreC; pfam04085
1157951007948	rod shape-determining protein MreD; Provisional; Region: PRK11060
1157951007949	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1157951007950	Maf-like protein; Region: Maf; pfam02545
1157951007951	active site
1157951007952	dimer interface [polypeptide binding]; other site
1157951007953	ribonuclease G; Provisional; Region: PRK11712
1157951007954	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1157951007955	homodimer interface [polypeptide binding]; other site
1157951007956	oligonucleotide binding site [chemical binding]; other site
1157951007957	hypothetical protein; Provisional; Region: PRK10899
1157951007958	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1157951007959	nitrilase; Region: PLN02798
1157951007960	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
1157951007961	putative active site [active]
1157951007962	catalytic triad [active]
1157951007963	dimer interface [polypeptide binding]; other site
1157951007964	protease TldD; Provisional; Region: tldD; PRK10735
1157951007965	microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential  for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th,  Pb, N1, and Ms) and...; Region: microbial_RNases; cl00212
1157951007966	active site
1157951007967	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1157951007968	RNAase interaction site [polypeptide binding]; other site
1157951007969	Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545
1157951007970	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1157951007971	Low molecular weight phosphatase family; Region: LMWPc; cl00105
1157951007972	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1157951007973	active site
1157951007974	Leucine rich repeat; Region: LRR_8; pfam13855
1157951007975	hypothetical protein; Provisional; Region: PRK05255
1157951007976	peptidase PmbA; Provisional; Region: PRK11040
1157951007977	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1157951007978	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1157951007979	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1157951007980	dimerization domain swap beta strand [polypeptide binding]; other site
1157951007981	regulatory protein interface [polypeptide binding]; other site
1157951007982	active site
1157951007983	regulatory phosphorylation site [posttranslational modification]; other site
1157951007984	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
1157951007985	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1157951007986	active site
1157951007987	phosphorylation site [posttranslational modification]
1157951007988	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1157951007989	30S subunit binding site; other site
1157951007990	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1157951007991	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1157951007992	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1157951007993	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1157951007994	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1157951007995	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1157951007996	Walker A/P-loop; other site
1157951007997	ATP binding site [chemical binding]; other site
1157951007998	Q-loop/lid; other site
1157951007999	ABC transporter signature motif; other site
1157951008000	Walker B; other site
1157951008001	D-loop; other site
1157951008002	H-loop/switch region; other site
1157951008003	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1157951008004	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
1157951008005	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117; cl01200
1157951008006	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1157951008007	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1157951008008	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1157951008009	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1157951008010	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1157951008011	putative active site [active]
1157951008012	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1157951008013	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1157951008014	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1157951008015	Walker A/P-loop; other site
1157951008016	ATP binding site [chemical binding]; other site
1157951008017	Q-loop/lid; other site
1157951008018	ABC transporter signature motif; other site
1157951008019	Walker B; other site
1157951008020	D-loop; other site
1157951008021	H-loop/switch region; other site
1157951008022	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1157951008023	conserved hypothetical integral membrane protein; Region: TIGR00056
1157951008024	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1157951008025	mce related protein; Region: MCE; pfam02470
1157951008026	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1157951008027	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1157951008028	anti sigma factor interaction site; other site
1157951008029	regulatory phosphorylation site [posttranslational modification]; other site
1157951008030	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1157951008031	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1157951008032	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1157951008033	hinge; other site
1157951008034	active site
1157951008035	serine endoprotease; Provisional; Region: PRK10898
1157951008036	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1157951008037	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1157951008038	protein binding site [polypeptide binding]; other site
1157951008039	serine endoprotease; Provisional; Region: PRK10139
1157951008040	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1157951008041	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1157951008042	protein binding site [polypeptide binding]; other site
1157951008043	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1157951008044	protein binding site [polypeptide binding]; other site
1157951008045	hypothetical protein; Provisional; Region: PRK11677
1157951008046	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1157951008047	Predicted ATPase [General function prediction only]; Region: COG1485
1157951008048	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1157951008049	23S rRNA interface [nucleotide binding]; other site
1157951008050	L3 interface [polypeptide binding]; other site
1157951008051	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1157951008052	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1157951008053	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1157951008054	C-terminal domain interface [polypeptide binding]; other site
1157951008055	putative GSH binding site (G-site) [chemical binding]; other site
1157951008056	dimer interface [polypeptide binding]; other site
1157951008057	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1157951008058	dimer interface [polypeptide binding]; other site
1157951008059	N-terminal domain interface [polypeptide binding]; other site
1157951008060	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1157951008061	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1157951008062	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951008063	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951008064	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1157951008065	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1157951008066	active site
1157951008067	dimer interface [polypeptide binding]; other site
1157951008068	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1157951008069	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1157951008070	active site
1157951008071	FMN binding site [chemical binding]; other site
1157951008072	substrate binding site [chemical binding]; other site
1157951008073	3Fe-4S cluster binding site [ion binding]; other site
1157951008074	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1157951008075	domain interface; other site
1157951008076	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1157951008077	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1157951008078	putative active site [active]
1157951008079	heme pocket [chemical binding]; other site
1157951008080	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951008081	dimer interface [polypeptide binding]; other site
1157951008082	phosphorylation site [posttranslational modification]
1157951008083	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951008084	ATP binding site [chemical binding]; other site
1157951008085	Mg2+ binding site [ion binding]; other site
1157951008086	G-X-G motif; other site
1157951008087	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951008088	active site
1157951008089	phosphorylation site [posttranslational modification]
1157951008090	intermolecular recognition site; other site
1157951008091	dimerization interface [polypeptide binding]; other site
1157951008092	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1157951008093	putative binding surface; other site
1157951008094	active site
1157951008095	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1157951008096	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1157951008097	conserved cys residue [active]
1157951008098	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1157951008099	Transglycosylase; Region: Transgly; cl17702
1157951008100	outer membrane lipoprotein; Provisional; Region: PRK11023
1157951008101	BON domain; Region: BON; pfam04972
1157951008102	BON domain; Region: BON; pfam04972
1157951008103	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1157951008104	dimer interface [polypeptide binding]; other site
1157951008105	active site
1157951008106	hypothetical protein; Reviewed; Region: PRK12497
1157951008107	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1157951008108	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1157951008109	putative ligand binding site [chemical binding]; other site
1157951008110	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1157951008111	putative SAM binding site [chemical binding]; other site
1157951008112	putative homodimer interface [polypeptide binding]; other site
1157951008113	S-AdoMet dependent tetrapyrrole methylases; Region: TP_methylase; cl00304
1157951008114	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951008115	Sel1-like repeats; Region: SEL1; smart00671
1157951008116	Sel1-like repeats; Region: SEL1; smart00671
1157951008117	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1157951008118	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1157951008119	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951008120	catalytic residue [active]
1157951008121	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
1157951008122	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1157951008123	active site
1157951008124	Domain of unknown function (DUF4310); Region: DUF4310; pfam14187
1157951008125	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1157951008126	Domain of unknown function (DUF4312); Region: DUF4312; pfam14189
1157951008127	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; cl11916
1157951008128	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1157951008129	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1157951008130	HTH domain; Region: HTH_11; pfam08279
1157951008131	PRD domain; Region: PRD; pfam00874
1157951008132	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1157951008133	active site
1157951008134	P-loop; other site
1157951008135	phosphorylation site [posttranslational modification]
1157951008136	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1157951008137	active site
1157951008138	phosphorylation site [posttranslational modification]
1157951008139	Pirin-related protein [General function prediction only]; Region: COG1741
1157951008140	Pirin; Region: Pirin; pfam02678
1157951008141	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951008142	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1157951008143	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951008144	dimerization interface [polypeptide binding]; other site
1157951008145	Predicted membrane protein [Function unknown]; Region: COG2259
1157951008146	YqjK-like protein; Region: YqjK; pfam13997
1157951008147	Predicted membrane protein [Function unknown]; Region: COG5393
1157951008148	Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957
1157951008149	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1157951008150	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1157951008151	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1157951008152	serine/threonine transporter SstT; Provisional; Region: PRK13628
1157951008153	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1157951008154	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1157951008155	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1157951008156	active site
1157951008157	FMN binding site [chemical binding]; other site
1157951008158	2,4-decadienoyl-CoA binding site; other site
1157951008159	catalytic residue [active]
1157951008160	4Fe-4S cluster binding site [ion binding]; other site
1157951008161	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1157951008162	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1157951008163	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1157951008164	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1157951008165	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951008166	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951008167	putative substrate translocation pore; other site
1157951008168	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951008169	Sel1-like repeats; Region: SEL1; smart00671
1157951008170	Sel1 repeat; Region: Sel1; cl02723
1157951008171	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951008172	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951008173	non-specific DNA binding site [nucleotide binding]; other site
1157951008174	salt bridge; other site
1157951008175	sequence-specific DNA binding site [nucleotide binding]; other site
1157951008176	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951008177	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951008178	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1157951008179	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951008180	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951008181	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951008182	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1157951008183	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951008184	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951008185	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951008186	putative fimbrial protein StaE; Provisional; Region: PRK15263
1157951008187	Fimbrial protein; Region: Fimbrial; pfam00419
1157951008188	Fimbrial protein; Region: Fimbrial; pfam00419
1157951008189	Fimbrial protein; Region: Fimbrial; cl01416
1157951008190	Fimbrial protein; Region: Fimbrial; cl01416
1157951008191	putative chaperone protein EcpD; Provisional; Region: PRK09926
1157951008192	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951008193	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951008194	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951008195	Fimbrial protein; Region: Fimbrial; pfam00419
1157951008196	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951008197	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951008198	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951008199	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951008200	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951008201	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951008202	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951008203	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951008204	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951008205	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951008206	flavin-containing monooxygenase FMO GS-OX; Region: PLN02172
1157951008207	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cl02500
1157951008208	HdeA/HdeB family; Region: HdeA; pfam06411
1157951008209	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1157951008210	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951008211	N-terminal plug; other site
1157951008212	ligand-binding site [chemical binding]; other site
1157951008213	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1157951008214	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1157951008215	intersubunit interface [polypeptide binding]; other site
1157951008216	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951008217	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951008218	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1157951008219	putative effector binding pocket; other site
1157951008220	dimerization interface [polypeptide binding]; other site
1157951008221	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951008222	putative substrate translocation pore; other site
1157951008223	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1157951008224	Predicted transcriptional regulator [Transcription]; Region: COG2378
1157951008225	HTH domain; Region: HTH_11; cl17392
1157951008226	WYL domain; Region: WYL; pfam13280
1157951008227	Flagellin N-methylase; Region: FliB; pfam03692
1157951008228	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951008229	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951008230	putative substrate translocation pore; other site
1157951008231	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951008232	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1157951008233	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1157951008234	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1157951008235	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1157951008236	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1157951008237	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1157951008238	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1157951008239	DNA binding residues [nucleotide binding]
1157951008240	DNA primase; Validated; Region: dnaG; PRK05667
1157951008241	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1157951008242	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1157951008243	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1157951008244	active site
1157951008245	metal binding site [ion binding]; metal-binding site
1157951008246	interdomain interaction site; other site
1157951008247	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1157951008248	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1157951008249	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1157951008250	UGMP family protein; Validated; Region: PRK09604
1157951008251	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1157951008252	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1157951008253	PAS fold; Region: PAS_3; pfam08447
1157951008254	putative active site [active]
1157951008255	heme pocket [chemical binding]; other site
1157951008256	HAMP domain; Region: HAMP; pfam00672
1157951008257	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1157951008258	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1157951008259	dimer interface [polypeptide binding]; other site
1157951008260	putative CheW interface [polypeptide binding]; other site
1157951008261	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1157951008262	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1157951008263	homooctamer interface [polypeptide binding]; other site
1157951008264	active site
1157951008265	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1157951008266	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1157951008267	active site
1157951008268	NTP binding site [chemical binding]; other site
1157951008269	metal binding triad [ion binding]; metal-binding site
1157951008270	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1157951008271	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1157951008272	Zn2+ binding site [ion binding]; other site
1157951008273	Mg2+ binding site [ion binding]; other site
1157951008274	SH3 domain-containing protein; Provisional; Region: PRK10884
1157951008275	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1157951008276	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1157951008277	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1157951008278	putative active site [active]
1157951008279	putative metal binding residues [ion binding]; other site
1157951008280	signature motif; other site
1157951008281	putative triphosphate binding site [ion binding]; other site
1157951008282	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1157951008283	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1157951008284	metal binding triad; other site
1157951008285	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1157951008286	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1157951008287	metal binding triad; other site
1157951008288	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1157951008289	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1157951008290	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1157951008291	putative ribose interaction site [chemical binding]; other site
1157951008292	putative ADP binding site [chemical binding]; other site
1157951008293	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1157951008294	active site
1157951008295	nucleotide binding site [chemical binding]; other site
1157951008296	HIGH motif; other site
1157951008297	KMSKS motif; other site
1157951008298	Membrane fusogenic activity; Region: BMFP; cl01115
1157951008299	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1157951008300	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1157951008301	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1157951008302	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1157951008303	putative active site [active]
1157951008304	metal binding site [ion binding]; metal-binding site
1157951008305	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1157951008306	hypothetical protein; Provisional; Region: PRK11653
1157951008307	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1157951008308	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1157951008309	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1157951008310	dimer interface [polypeptide binding]; other site
1157951008311	ADP-ribose binding site [chemical binding]; other site
1157951008312	active site
1157951008313	nudix motif; other site
1157951008314	metal binding site [ion binding]; metal-binding site
1157951008315	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1157951008316	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1157951008317	active site
1157951008318	metal binding site [ion binding]; metal-binding site
1157951008319	hexamer interface [polypeptide binding]; other site
1157951008320	esterase YqiA; Provisional; Region: PRK11071
1157951008321	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1157951008322	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1157951008323	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951008324	ATP binding site [chemical binding]; other site
1157951008325	Mg2+ binding site [ion binding]; other site
1157951008326	G-X-G motif; other site
1157951008327	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1157951008328	anchoring element; other site
1157951008329	dimer interface [polypeptide binding]; other site
1157951008330	ATP binding site [chemical binding]; other site
1157951008331	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1157951008332	active site
1157951008333	metal binding site [ion binding]; metal-binding site
1157951008334	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1157951008335	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1157951008336	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1157951008337	CAP-like domain; other site
1157951008338	active site
1157951008339	primary dimer interface [polypeptide binding]; other site
1157951008340	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1157951008341	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1157951008342	putative acyl-acceptor binding pocket; other site
1157951008343	FtsI repressor; Provisional; Region: PRK10883
1157951008344	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1157951008345	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1157951008346	PAAR motif; Region: PAAR_motif; pfam05488
1157951008347	PAAR motif; Region: PAAR_motif; cl15808
1157951008348	PAAR motif; Region: PAAR_motif; cl15808
1157951008349	PAAR motif; Region: PAAR_motif; pfam05488
1157951008350	RHS Repeat; Region: RHS_repeat; pfam05593
1157951008351	RHS Repeat; Region: RHS_repeat; cl11982
1157951008352	RHS Repeat; Region: RHS_repeat; cl11982
1157951008353	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1157951008354	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1157951008355	RHS Repeat; Region: RHS_repeat; pfam05593
1157951008356	RHS protein; Region: RHS; pfam03527
1157951008357	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951008358	A nuclease family of the HNH/ENDO VII superfamily with conserved AHH; Region: AHH; pfam14412
1157951008359	Domain of unknown function (DUF1795); Region: DUF1795; cl02256
1157951008360	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1157951008361	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1157951008362	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1157951008363	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1157951008364	LysE type translocator; Region: LysE; cl00565
1157951008365	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1157951008366	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1157951008367	folate binding site [chemical binding]; other site
1157951008368	NADP+ binding site [chemical binding]; other site
1157951008369	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
1157951008370	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1157951008371	active site
1157951008372	metal binding site [ion binding]; metal-binding site
1157951008373	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1157951008374	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1157951008375	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1157951008376	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1157951008377	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1157951008378	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1157951008379	SurA N-terminal domain; Region: SurA_N; pfam09312
1157951008380	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1157951008381	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1157951008382	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1157951008383	OstA-like protein; Region: OstA; pfam03968
1157951008384	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1157951008385	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1157951008386	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1157951008387	putative metal binding site [ion binding]; other site
1157951008388	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1157951008389	HSP70 interaction site [polypeptide binding]; other site
1157951008390	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1157951008391	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1157951008392	active site
1157951008393	ATP-dependent helicase HepA; Validated; Region: PRK04914
1157951008394	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951008395	ATP binding site [chemical binding]; other site
1157951008396	putative Mg++ binding site [ion binding]; other site
1157951008397	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951008398	nucleotide binding region [chemical binding]; other site
1157951008399	ATP-binding site [chemical binding]; other site
1157951008400	DNA polymerase II; Reviewed; Region: PRK05762
1157951008401	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1157951008402	active site
1157951008403	catalytic site [active]
1157951008404	substrate binding site [chemical binding]; other site
1157951008405	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1157951008406	active site
1157951008407	metal-binding site
1157951008408	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1157951008409	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951008410	Walker A/P-loop; other site
1157951008411	ATP binding site [chemical binding]; other site
1157951008412	Q-loop/lid; other site
1157951008413	ABC transporter signature motif; other site
1157951008414	Walker B; other site
1157951008415	D-loop; other site
1157951008416	H-loop/switch region; other site
1157951008417	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1157951008418	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951008419	dimer interface [polypeptide binding]; other site
1157951008420	conserved gate region; other site
1157951008421	putative PBP binding loops; other site
1157951008422	ABC-ATPase subunit interface; other site
1157951008423	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1157951008424	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1157951008425	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1157951008426	putative active site [active]
1157951008427	Ap4A binding site [chemical binding]; other site
1157951008428	nudix motif; other site
1157951008429	putative metal binding site [ion binding]; other site
1157951008430	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1157951008431	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1157951008432	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1157951008433	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1157951008434	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1157951008435	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1157951008436	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1157951008437	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1157951008438	dimerization interface [polypeptide binding]; other site
1157951008439	active site
1157951008440	hypothetical protein; Provisional; Region: PRK10506
1157951008441	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1157951008442	hypothetical protein; Provisional; Region: PRK10557
1157951008443	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1157951008444	Protein of unknown function (DUF2509); Region: DUF2509; cl11672
1157951008445	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1157951008446	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1157951008447	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
1157951008448	protease3; Provisional; Region: PRK15101
1157951008449	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1157951008450	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1157951008451	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1157951008452	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1157951008453	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1157951008454	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1157951008455	AAA domain; Region: AAA_30; pfam13604
1157951008456	Family description; Region: UvrD_C_2; pfam13538
1157951008457	N-acetylglutamate synthase; Validated; Region: PRK05279
1157951008458	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1157951008459	putative feedback inhibition sensing region; other site
1157951008460	putative nucleotide binding site [chemical binding]; other site
1157951008461	putative substrate binding site [chemical binding]; other site
1157951008462	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951008463	Coenzyme A binding pocket [chemical binding]; other site
1157951008464	AMIN domain; Region: AMIN; pfam11741
1157951008465	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1157951008466	active site
1157951008467	metal binding site [ion binding]; metal-binding site
1157951008468	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1157951008469	MltA specific insert domain; Region: MltA; smart00925
1157951008470	3D domain; Region: 3D; pfam06725
1157951008471	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1157951008472	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1157951008473	putative ATP binding site [chemical binding]; other site
1157951008474	putative substrate interface [chemical binding]; other site
1157951008475	Fe-S metabolism associated domain; Region: SufE; cl00951
1157951008476	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1157951008477	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1157951008478	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951008479	catalytic residue [active]
1157951008480	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1157951008481	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951008482	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1157951008483	dimerization interface [polypeptide binding]; other site
1157951008484	substrate binding pocket [chemical binding]; other site
1157951008485	hypothetical protein; Provisional; Region: PRK10873
1157951008486	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1157951008487	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1157951008488	flap endonuclease-like protein; Provisional; Region: PRK09482
1157951008489	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1157951008490	active site
1157951008491	metal binding site 1 [ion binding]; metal-binding site
1157951008492	putative 5' ssDNA interaction site; other site
1157951008493	metal binding site 3; metal-binding site
1157951008494	metal binding site 2 [ion binding]; metal-binding site
1157951008495	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1157951008496	putative DNA binding site [nucleotide binding]; other site
1157951008497	putative metal binding site [ion binding]; other site
1157951008498	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1157951008499	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1157951008500	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1157951008501	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1157951008502	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1157951008503	SecY interacting protein Syd; Provisional; Region: PRK04968
1157951008504	Protein of unknown function (DUF535); Region: DUF535; cl01128
1157951008505	tRNA pseudouridine synthase C; Region: DUF446; pfam04287
1157951008506	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1157951008507	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1157951008508	probable active site [active]
1157951008509	flavodoxin; Provisional; Region: PRK08105
1157951008510	hypothetical protein; Provisional; Region: PRK13677
1157951008511	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1157951008512	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1157951008513	trimer interface [polypeptide binding]; other site
1157951008514	active site
1157951008515	substrate binding site [chemical binding]; other site
1157951008516	CoA binding site [chemical binding]; other site
1157951008517	PII uridylyl-transferase; Provisional; Region: PRK05007
1157951008518	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1157951008519	metal binding triad; other site
1157951008520	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1157951008521	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1157951008522	Zn2+ binding site [ion binding]; other site
1157951008523	Mg2+ binding site [ion binding]; other site
1157951008524	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1157951008525	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1157951008526	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1157951008527	active site
1157951008528	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1157951008529	rRNA interaction site [nucleotide binding]; other site
1157951008530	S8 interaction site; other site
1157951008531	putative laminin-1 binding site; other site
1157951008532	elongation factor Ts; Provisional; Region: tsf; PRK09377
1157951008533	UBA/TS-N domain; Region: UBA; pfam00627
1157951008534	Elongation factor TS; Region: EF_TS; pfam00889
1157951008535	Elongation factor TS; Region: EF_TS; pfam00889
1157951008536	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1157951008537	putative nucleotide binding site [chemical binding]; other site
1157951008538	uridine monophosphate binding site [chemical binding]; other site
1157951008539	homohexameric interface [polypeptide binding]; other site
1157951008540	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1157951008541	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1157951008542	hinge region; other site
1157951008543	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1157951008544	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1157951008545	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1157951008546	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1157951008547	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1157951008548	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1157951008549	catalytic residue [active]
1157951008550	putative FPP diphosphate  binding site; other site
1157951008551	putative FPP binding hydrophobic cleft; other site
1157951008552	dimer interface [polypeptide binding]; other site
1157951008553	putative IPP diphosphate binding site; other site
1157951008554	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1157951008555	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1157951008556	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1157951008557	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1157951008558	active site
1157951008559	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1157951008560	protein binding site [polypeptide binding]; other site
1157951008561	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1157951008562	protein binding site [polypeptide binding]; other site
1157951008563	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1157951008564	putative substrate binding region [chemical binding]; other site
1157951008565	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1157951008566	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1157951008567	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1157951008568	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1157951008569	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1157951008570	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1157951008571	Surface antigen; Region: Bac_surface_Ag; pfam01103
1157951008572	periplasmic chaperone; Provisional; Region: PRK10780
1157951008573	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1157951008574	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1157951008575	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1157951008576	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1157951008577	trimer interface [polypeptide binding]; other site
1157951008578	active site
1157951008579	UDP-GlcNAc binding site [chemical binding]; other site
1157951008580	lipid binding site [chemical binding]; lipid-binding site
1157951008581	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1157951008582	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1157951008583	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1157951008584	active site
1157951008585	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1157951008586	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1157951008587	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1157951008588	RNA/DNA hybrid binding site [nucleotide binding]; other site
1157951008589	active site
1157951008590	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1157951008591	PHP domain; Region: PHP; pfam02811
1157951008592	putative active site [active]
1157951008593	putative PHP Thumb interface [polypeptide binding]; other site
1157951008594	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1157951008595	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
1157951008596	DNA polymerase III subunit alpha; Reviewed; Region: PRK07373
1157951008597	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1157951008598	generic binding surface II; other site
1157951008599	generic binding surface I; other site
1157951008600	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1157951008601	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1157951008602	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1157951008603	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1157951008604	Ligand Binding Site [chemical binding]; other site
1157951008605	TilS substrate binding domain; Region: TilS; pfam09179
1157951008606	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1157951008607	Modulator of Rho-dependent transcription termination (ROF); Region: ROF; cl09210
1157951008608	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1157951008609	NlpE N-terminal domain; Region: NlpE; pfam04170
1157951008610	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1157951008611	active site
1157951008612	P-loop; other site
1157951008613	phosphorylation site [posttranslational modification]
1157951008614	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
1157951008615	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1157951008616	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1157951008617	methionine cluster; other site
1157951008618	active site
1157951008619	phosphorylation site [posttranslational modification]
1157951008620	metal binding site [ion binding]; metal-binding site
1157951008621	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1157951008622	Cupin domain; Region: Cupin_2; cl17218
1157951008623	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951008624	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1157951008625	NAD(P) binding site [chemical binding]; other site
1157951008626	LDH/MDH dimer interface [polypeptide binding]; other site
1157951008627	substrate binding site [chemical binding]; other site
1157951008628	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1157951008629	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
1157951008630	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
1157951008631	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1157951008632	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1157951008633	dimer interface [polypeptide binding]; other site
1157951008634	motif 1; other site
1157951008635	active site
1157951008636	motif 2; other site
1157951008637	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1157951008638	putative deacylase active site [active]
1157951008639	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1157951008640	active site
1157951008641	motif 3; other site
1157951008642	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1157951008643	anticodon binding site; other site
1157951008644	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1157951008645	homodimer interaction site [polypeptide binding]; other site
1157951008646	cofactor binding site; other site
1157951008647	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1157951008648	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1157951008649	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1157951008650	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951008651	dimer interface [polypeptide binding]; other site
1157951008652	conserved gate region; other site
1157951008653	ABC-ATPase subunit interface; other site
1157951008654	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1157951008655	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1157951008656	Walker A/P-loop; other site
1157951008657	ATP binding site [chemical binding]; other site
1157951008658	Q-loop/lid; other site
1157951008659	ABC transporter signature motif; other site
1157951008660	Walker B; other site
1157951008661	D-loop; other site
1157951008662	H-loop/switch region; other site
1157951008663	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1157951008664	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
1157951008665	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951008666	active site
1157951008667	motif I; other site
1157951008668	motif II; other site
1157951008669	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1157951008670	lipoprotein; Provisional; Region: PRK10759
1157951008671	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1157951008672	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1157951008673	domain interface [polypeptide binding]; other site
1157951008674	putative active site [active]
1157951008675	catalytic site [active]
1157951008676	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1157951008677	domain interface [polypeptide binding]; other site
1157951008678	putative active site [active]
1157951008679	catalytic site [active]
1157951008680	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1157951008681	CoA binding domain; Region: CoA_binding_2; pfam13380
1157951008682	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1157951008683	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1157951008684	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1157951008685	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1157951008686	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1157951008687	putative methyltransferase; Provisional; Region: PRK10864
1157951008688	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1157951008689	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1157951008690	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1157951008691	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951008692	putative substrate translocation pore; other site
1157951008693	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951008694	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1157951008695	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951008696	transcriptional repressor MprA; Provisional; Region: PRK10870
1157951008697	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1157951008698	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1157951008699	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951008700	putative substrate translocation pore; other site
1157951008701	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1157951008702	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1157951008703	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1157951008704	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951008705	dimer interface [polypeptide binding]; other site
1157951008706	conserved gate region; other site
1157951008707	putative PBP binding loops; other site
1157951008708	ABC-ATPase subunit interface; other site
1157951008709	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1157951008710	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1157951008711	Walker A/P-loop; other site
1157951008712	ATP binding site [chemical binding]; other site
1157951008713	Q-loop/lid; other site
1157951008714	ABC transporter signature motif; other site
1157951008715	Walker B; other site
1157951008716	D-loop; other site
1157951008717	H-loop/switch region; other site
1157951008718	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1157951008719	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1157951008720	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1157951008721	dimer interface [polypeptide binding]; other site
1157951008722	putative radical transfer pathway; other site
1157951008723	diiron center [ion binding]; other site
1157951008724	tyrosyl radical; other site
1157951008725	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1157951008726	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1157951008727	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1157951008728	active site
1157951008729	dimer interface [polypeptide binding]; other site
1157951008730	catalytic residues [active]
1157951008731	effector binding site; other site
1157951008732	R2 peptide binding site; other site
1157951008733	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1157951008734	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1157951008735	catalytic residues [active]
1157951008736	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1157951008737	DNA binding site [nucleotide binding]
1157951008738	active site
1157951008739	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1157951008740	DNA-binding site [nucleotide binding]; DNA binding site
1157951008741	RNA-binding motif; other site
1157951008742	lipoyl synthase; Provisional; Region: PRK05481
1157951008743	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951008744	FeS/SAM binding site; other site
1157951008745	lipoate-protein ligase B; Provisional; Region: PRK14342
1157951008746	hypothetical protein; Provisional; Region: PRK04998
1157951008747	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1157951008748	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1157951008749	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1157951008750	rare lipoprotein A; Provisional; Region: PRK10672
1157951008751	Sporulation related domain; Region: SPOR; pfam05036
1157951008752	cell wall shape-determining protein; Provisional; Region: PRK10794
1157951008753	penicillin-binding protein 2; Provisional; Region: PRK10795
1157951008754	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1157951008755	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1157951008756	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1157951008757	ribosome-associated protein; Provisional; Region: PRK11538
1157951008758	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1157951008759	Protein of unknown function (DUF1722); Region: DUF1722; pfam08349
1157951008760	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1157951008761	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1157951008762	active site
1157951008763	(T/H)XGH motif; other site
1157951008764	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1157951008765	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1157951008766	Lipopolysaccharide-assembly; Region: LptE; cl01125
1157951008767	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1157951008768	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1157951008769	HIGH motif; other site
1157951008770	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1157951008771	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1157951008772	active site
1157951008773	KMSKS motif; other site
1157951008774	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1157951008775	tRNA binding surface [nucleotide binding]; other site
1157951008776	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951008777	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1157951008778	Coenzyme A binding pocket [chemical binding]; other site
1157951008779	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1157951008780	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1157951008781	Walker A/P-loop; other site
1157951008782	ATP binding site [chemical binding]; other site
1157951008783	Q-loop/lid; other site
1157951008784	ABC transporter signature motif; other site
1157951008785	Walker B; other site
1157951008786	D-loop; other site
1157951008787	H-loop/switch region; other site
1157951008788	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1157951008789	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951008790	dimer interface [polypeptide binding]; other site
1157951008791	conserved gate region; other site
1157951008792	putative PBP binding loops; other site
1157951008793	ABC-ATPase subunit interface; other site
1157951008794	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951008795	dimer interface [polypeptide binding]; other site
1157951008796	conserved gate region; other site
1157951008797	putative PBP binding loops; other site
1157951008798	ABC-ATPase subunit interface; other site
1157951008799	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1157951008800	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1157951008801	substrate binding pocket [chemical binding]; other site
1157951008802	membrane-bound complex binding site; other site
1157951008803	hinge residues; other site
1157951008804	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
1157951008805	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
1157951008806	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1157951008807	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1157951008808	DsbD alpha interface [polypeptide binding]; other site
1157951008809	catalytic residues [active]
1157951008810	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1157951008811	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1157951008812	catalytic residues [active]
1157951008813	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1157951008814	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1157951008815	catalytic residues [active]
1157951008816	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
1157951008817	nudix motif; other site
1157951008818	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
1157951008819	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1157951008820	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1157951008821	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1157951008822	putative active site [active]
1157951008823	catalytic triad [active]
1157951008824	putative dimer interface [polypeptide binding]; other site
1157951008825	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1157951008826	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1157951008827	Transporter associated domain; Region: CorC_HlyC; smart01091
1157951008828	metal-binding heat shock protein; Provisional; Region: PRK00016
1157951008829	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1157951008830	PhoH-like protein; Region: PhoH; pfam02562
1157951008831	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1157951008832	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1157951008833	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951008834	FeS/SAM binding site; other site
1157951008835	TRAM domain; Region: TRAM; pfam01938
1157951008836	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1157951008837	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1157951008838	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1157951008839	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1157951008840	phosphoenolpyruvate synthase; Validated; Region: PRK06241
1157951008841	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1157951008842	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1157951008843	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1157951008844	active site
1157951008845	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Region: LPLAT_AAK14816-like; cd07992
1157951008846	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1157951008847	putative acyl-acceptor binding pocket; other site
1157951008848	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1157951008849	MarR family; Region: MarR; pfam01047
1157951008850	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1157951008851	ROK family; Region: ROK; pfam00480
1157951008852	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1157951008853	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1157951008854	active site
1157951008855	dimer interface [polypeptide binding]; other site
1157951008856	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1157951008857	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1157951008858	active site
1157951008859	trimer interface [polypeptide binding]; other site
1157951008860	allosteric site; other site
1157951008861	active site lid [active]
1157951008862	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1157951008863	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1157951008864	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1157951008865	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1157951008866	active site turn [active]
1157951008867	phosphorylation site [posttranslational modification]
1157951008868	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1157951008869	HPr interaction site; other site
1157951008870	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1157951008871	active site
1157951008872	phosphorylation site [posttranslational modification]
1157951008873	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1157951008874	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1157951008875	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1157951008876	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1157951008877	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1157951008878	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
1157951008879	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1157951008880	PAAR motif; Region: PAAR_motif; pfam05488
1157951008881	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
1157951008882	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
1157951008883	Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480
1157951008884	Integrase core domain; Region: rve; pfam00665
1157951008885	Integrase core domain; Region: rve_3; pfam13683
1157951008886	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951008887	Sel1 repeat; Region: Sel1; cl02723
1157951008888	HTH-like domain; Region: HTH_21; pfam13276
1157951008889	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1157951008890	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1157951008891	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1157951008892	active site
1157951008893	HIGH motif; other site
1157951008894	nucleotide binding site [chemical binding]; other site
1157951008895	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1157951008896	KMSKS motif; other site
1157951008897	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1157951008898	hypothetical protein; Provisional; Region: PRK10318
1157951008899	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1157951008900	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951008901	active site
1157951008902	phosphorylation site [posttranslational modification]
1157951008903	intermolecular recognition site; other site
1157951008904	dimerization interface [polypeptide binding]; other site
1157951008905	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1157951008906	DNA binding site [nucleotide binding]
1157951008907	sensor protein KdpD; Provisional; Region: PRK10490
1157951008908	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1157951008909	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1157951008910	Ligand Binding Site [chemical binding]; other site
1157951008911	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1157951008912	GAF domain; Region: GAF_3; pfam13492
1157951008913	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951008914	dimer interface [polypeptide binding]; other site
1157951008915	phosphorylation site [posttranslational modification]
1157951008916	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951008917	ATP binding site [chemical binding]; other site
1157951008918	Mg2+ binding site [ion binding]; other site
1157951008919	G-X-G motif; other site
1157951008920	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1157951008921	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1157951008922	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1157951008923	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1157951008924	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1157951008925	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
1157951008926	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1157951008927	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951008928	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1157951008929	putative substrate translocation pore; other site
1157951008930	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1157951008931	Helix-turn-helix domain; Region: HTH_18; pfam12833
1157951008932	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1157951008933	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1157951008934	dimer interface [polypeptide binding]; other site
1157951008935	active site
1157951008936	citrylCoA binding site [chemical binding]; other site
1157951008937	NADH binding [chemical binding]; other site
1157951008938	cationic pore residues; other site
1157951008939	oxalacetate/citrate binding site [chemical binding]; other site
1157951008940	coenzyme A binding site [chemical binding]; other site
1157951008941	catalytic triad [active]
1157951008942	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1157951008943	Iron-sulfur protein interface; other site
1157951008944	proximal quinone binding site [chemical binding]; other site
1157951008945	SdhD (CybS) interface [polypeptide binding]; other site
1157951008946	proximal heme binding site [chemical binding]; other site
1157951008947	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1157951008948	SdhC subunit interface [polypeptide binding]; other site
1157951008949	proximal heme binding site [chemical binding]; other site
1157951008950	cardiolipin binding site; other site
1157951008951	Iron-sulfur protein interface; other site
1157951008952	proximal quinone binding site [chemical binding]; other site
1157951008953	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1157951008954	L-aspartate oxidase; Provisional; Region: PRK06175
1157951008955	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1157951008956	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1157951008957	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1157951008958	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1157951008959	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1157951008960	TPP-binding site [chemical binding]; other site
1157951008961	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1157951008962	dimer interface [polypeptide binding]; other site
1157951008963	PYR/PP interface [polypeptide binding]; other site
1157951008964	TPP binding site [chemical binding]; other site
1157951008965	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1157951008966	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1157951008967	E3 interaction surface; other site
1157951008968	lipoyl attachment site [posttranslational modification]; other site
1157951008969	e3 binding domain; Region: E3_binding; pfam02817
1157951008970	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1157951008971	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1157951008972	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1157951008973	CoA-ligase; Region: Ligase_CoA; pfam00549
1157951008974	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1157951008975	CoA binding domain; Region: CoA_binding; smart00881
1157951008976	CoA-ligase; Region: Ligase_CoA; pfam00549
1157951008977	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1157951008978	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1157951008979	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1157951008980	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1157951008981	Membrane bound YbgT-like protein; Region: YbgT_YccB; pfam08173
1157951008982	Cyd operon protein YbgE (Cyd_oper_YbgE); Region: Cyd_oper_YbgE; cl11451
1157951008983	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1157951008984	active site
1157951008985	colicin uptake protein TolQ; Provisional; Region: PRK10801
1157951008986	colicin uptake protein TolR; Provisional; Region: PRK11024
1157951008987	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1157951008988	TolA C-terminal; Region: TolA; pfam06519
1157951008989	translocation protein TolB; Provisional; Region: tolB; PRK03629
1157951008990	TolB amino-terminal domain; Region: TolB_N; pfam04052
1157951008991	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1157951008992	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1157951008993	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1157951008994	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1157951008995	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1157951008996	ligand binding site [chemical binding]; other site
1157951008997	tol-pal system protein YbgF; Provisional; Region: PRK10803
1157951008998	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1157951008999	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1157951009000	active site
1157951009001	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1157951009002	Streptomycin adenylyltransferase; Region: Adenyl_transf; pfam04439
1157951009003	quinolinate synthetase; Provisional; Region: PRK09375
1157951009004	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1157951009005	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1157951009006	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1157951009007	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1157951009008	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1157951009009	catalytic core [active]
1157951009010	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1157951009011	CAAX protease self-immunity; Region: Abi; pfam02517
1157951009012	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1157951009013	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009014	Walker A/P-loop; other site
1157951009015	ATP binding site [chemical binding]; other site
1157951009016	ABC transporter signature motif; other site
1157951009017	Walker B; other site
1157951009018	D-loop; other site
1157951009019	H-loop/switch region; other site
1157951009020	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009021	Walker A/P-loop; other site
1157951009022	ATP binding site [chemical binding]; other site
1157951009023	Q-loop/lid; other site
1157951009024	ABC transporter signature motif; other site
1157951009025	Walker B; other site
1157951009026	D-loop; other site
1157951009027	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1157951009028	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1157951009029	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1157951009030	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
1157951009031	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1157951009032	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1157951009033	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1157951009034	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1157951009035	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951009036	dimer interface [polypeptide binding]; other site
1157951009037	conserved gate region; other site
1157951009038	putative PBP binding loops; other site
1157951009039	ABC-ATPase subunit interface; other site
1157951009040	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1157951009041	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009042	Walker A/P-loop; other site
1157951009043	ATP binding site [chemical binding]; other site
1157951009044	Q-loop/lid; other site
1157951009045	ABC transporter signature motif; other site
1157951009046	Walker B; other site
1157951009047	D-loop; other site
1157951009048	H-loop/switch region; other site
1157951009049	TOBE domain; Region: TOBE; cl01440
1157951009050	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1157951009051	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951009052	active site
1157951009053	motif I; other site
1157951009054	motif II; other site
1157951009055	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1157951009056	6-phosphogluconolactonase; Provisional; Region: PRK11028
1157951009057	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1157951009058	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1157951009059	inhibitor-cofactor binding pocket; inhibition site
1157951009060	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951009061	catalytic residue [active]
1157951009062	biotin synthase; Provisional; Region: PRK15108
1157951009063	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951009064	FeS/SAM binding site; other site
1157951009065	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1157951009066	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
1157951009067	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1157951009068	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951009069	catalytic residue [active]
1157951009070	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1157951009071	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951009072	S-adenosylmethionine binding site [chemical binding]; other site
1157951009073	AAA domain; Region: AAA_26; pfam13500
1157951009074	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1157951009075	excinuclease ABC subunit B; Provisional; Region: PRK05298
1157951009076	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951009077	ATP binding site [chemical binding]; other site
1157951009078	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951009079	nucleotide binding region [chemical binding]; other site
1157951009080	ATP-binding site [chemical binding]; other site
1157951009081	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1157951009082	UvrB/uvrC motif; Region: UVR; pfam02151
1157951009083	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1157951009084	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1157951009085	putative substrate binding pocket [chemical binding]; other site
1157951009086	dimer interface [polypeptide binding]; other site
1157951009087	phosphate binding site [ion binding]; other site
1157951009088	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1157951009089	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951009090	FeS/SAM binding site; other site
1157951009091	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1157951009092	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1157951009093	trimer interface [polypeptide binding]; other site
1157951009094	dimer interface [polypeptide binding]; other site
1157951009095	putative active site [active]
1157951009096	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1157951009097	MoaE interaction surface [polypeptide binding]; other site
1157951009098	MoeB interaction surface [polypeptide binding]; other site
1157951009099	thiocarboxylated glycine; other site
1157951009100	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1157951009101	MoaE homodimer interface [polypeptide binding]; other site
1157951009102	MoaD interaction [polypeptide binding]; other site
1157951009103	active site residues [active]
1157951009104	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1157951009105	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1157951009106	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1157951009107	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1157951009108	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1157951009109	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1157951009110	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1157951009111	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1157951009112	Walker A/P-loop; other site
1157951009113	ATP binding site [chemical binding]; other site
1157951009114	Q-loop/lid; other site
1157951009115	ABC transporter signature motif; other site
1157951009116	Walker B; other site
1157951009117	D-loop; other site
1157951009118	H-loop/switch region; other site
1157951009119	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1157951009120	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1157951009121	Walker A/P-loop; other site
1157951009122	ATP binding site [chemical binding]; other site
1157951009123	Q-loop/lid; other site
1157951009124	ABC transporter signature motif; other site
1157951009125	Walker B; other site
1157951009126	D-loop; other site
1157951009127	H-loop/switch region; other site
1157951009128	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1157951009129	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951009130	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951009131	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1157951009132	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951009133	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1157951009134	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1157951009135	ATP binding site [chemical binding]; other site
1157951009136	Mg++ binding site [ion binding]; other site
1157951009137	motif III; other site
1157951009138	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951009139	nucleotide binding region [chemical binding]; other site
1157951009140	ATP-binding site [chemical binding]; other site
1157951009141	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1157951009142	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1157951009143	FMN binding site [chemical binding]; other site
1157951009144	active site
1157951009145	catalytic residues [active]
1157951009146	substrate binding site [chemical binding]; other site
1157951009147	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1157951009148	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1157951009149	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1157951009150	active site residue [active]
1157951009151	Protein of unknown function (DUF2685); Region: DUF2685; cl17611
1157951009152	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1157951009153	active site residue [active]
1157951009154	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1157951009155	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1157951009156	DEAD_2; Region: DEAD_2; pfam06733
1157951009157	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1157951009158	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1157951009159	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1157951009160	dimerization interface [polypeptide binding]; other site
1157951009161	DPS ferroxidase diiron center [ion binding]; other site
1157951009162	ion pore; other site
1157951009163	threonine and homoserine efflux system; Provisional; Region: PRK10532
1157951009164	EamA-like transporter family; Region: EamA; pfam00892
1157951009165	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1157951009166	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1157951009167	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951009168	Coenzyme A binding pocket [chemical binding]; other site
1157951009169	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1157951009170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009171	Walker A/P-loop; other site
1157951009172	ATP binding site [chemical binding]; other site
1157951009173	Q-loop/lid; other site
1157951009174	ABC transporter signature motif; other site
1157951009175	Walker B; other site
1157951009176	D-loop; other site
1157951009177	H-loop/switch region; other site
1157951009178	ABC transporter; Region: ABC_tran_2; pfam12848
1157951009179	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951009180	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951009181	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951009182	non-specific DNA binding site [nucleotide binding]; other site
1157951009183	salt bridge; other site
1157951009184	sequence-specific DNA binding site [nucleotide binding]; other site
1157951009185	Fimbrial protein; Region: Fimbrial; cl01416
1157951009186	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951009187	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1157951009188	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951009189	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951009190	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951009191	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
1157951009192	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951009193	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951009194	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951009195	Fimbrial protein; Region: Fimbrial; pfam00419
1157951009196	Fimbrial protein; Region: Fimbrial; pfam00419
1157951009197	Fimbrial protein; Region: Fimbrial; cl01416
1157951009198	hypothetical protein; Provisional; Region: PRK10220
1157951009199	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1157951009200	PhnA protein; Region: PhnA; pfam03831
1157951009201	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1157951009202	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1157951009203	ATP binding site [chemical binding]; other site
1157951009204	substrate interface [chemical binding]; other site
1157951009205	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1157951009206	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1157951009207	dimer interface [polypeptide binding]; other site
1157951009208	putative functional site; other site
1157951009209	putative MPT binding site; other site
1157951009210	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951009211	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951009212	putative substrate translocation pore; other site
1157951009213	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1157951009214	homodecamer interface [polypeptide binding]; other site
1157951009215	GTP cyclohydrolase I; Provisional; Region: PLN03044
1157951009216	active site
1157951009217	putative catalytic site residues [active]
1157951009218	zinc binding site [ion binding]; other site
1157951009219	GTP-CH-I/GFRP interaction surface; other site
1157951009220	Predicted membrane protein [Function unknown]; Region: COG2311
1157951009221	hypothetical protein; Provisional; Region: PRK10835
1157951009222	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1157951009223	putative active site [active]
1157951009224	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1157951009225	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1157951009226	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1157951009227	putative active site [active]
1157951009228	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1157951009229	Rhomboid family; Region: Rhomboid; pfam01694
1157951009230	malate dehydrogenase; Provisional; Region: PRK13529
1157951009231	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1157951009232	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1157951009233	NAD(P) binding site [chemical binding]; other site
1157951009234	cytidine deaminase; Provisional; Region: PRK09027
1157951009235	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1157951009236	active site
1157951009237	catalytic motif [active]
1157951009238	Zn binding site [ion binding]; other site
1157951009239	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1157951009240	active site
1157951009241	catalytic motif [active]
1157951009242	Zn binding site [ion binding]; other site
1157951009243	hypothetical protein; Provisional; Region: PRK10711
1157951009244	hypothetical protein; Provisional; Region: PRK01821
1157951009245	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1157951009246	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1157951009247	active site
1157951009248	HIGH motif; other site
1157951009249	KMSKS motif; other site
1157951009250	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1157951009251	tRNA binding surface [nucleotide binding]; other site
1157951009252	anticodon binding site; other site
1157951009253	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1157951009254	dimer interface [polypeptide binding]; other site
1157951009255	putative tRNA-binding site [nucleotide binding]; other site
1157951009256	antiporter inner membrane protein; Provisional; Region: PRK11670
1157951009257	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1157951009258	LemA family; Region: LemA; cl00742
1157951009259	Peptidase family M48; Region: Peptidase_M48; cl12018
1157951009260	Helix-turn-helix domain; Region: HTH_18; pfam12833
1157951009261	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951009262	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1157951009263	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1157951009264	putative [Fe4-S4] binding site [ion binding]; other site
1157951009265	putative molybdopterin cofactor binding site [chemical binding]; other site
1157951009266	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1157951009267	putative molybdopterin cofactor binding site; other site
1157951009268	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1157951009269	4Fe-4S binding domain; Region: Fer4; pfam00037
1157951009270	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1157951009271	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1157951009272	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1157951009273	putative assembly protein; Provisional; Region: PRK10833
1157951009274	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1157951009275	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1157951009276	ATP-binding site [chemical binding]; other site
1157951009277	Sugar specificity; other site
1157951009278	Pyrimidine base specificity; other site
1157951009279	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1157951009280	trimer interface [polypeptide binding]; other site
1157951009281	active site
1157951009282	putative assembly protein; Provisional; Region: PRK10833
1157951009283	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1157951009284	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1157951009285	FOG: CBS domain [General function prediction only]; Region: COG0517
1157951009286	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1157951009287	Transporter associated domain; Region: CorC_HlyC; smart01091
1157951009288	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1157951009289	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1157951009290	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1157951009291	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1157951009292	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951009293	putative substrate translocation pore; other site
1157951009294	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1157951009295	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1157951009296	trimer interface [polypeptide binding]; other site
1157951009297	active site
1157951009298	substrate binding site [chemical binding]; other site
1157951009299	CoA binding site [chemical binding]; other site
1157951009300	Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957
1157951009301	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1157951009302	putative deacylase active site [active]
1157951009303	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1157951009304	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1157951009305	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1157951009306	metal binding site [ion binding]; metal-binding site
1157951009307	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1157951009308	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1157951009309	substrate binding site [chemical binding]; other site
1157951009310	glutamase interaction surface [polypeptide binding]; other site
1157951009311	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1157951009312	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1157951009313	catalytic residues [active]
1157951009314	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1157951009315	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1157951009316	putative active site [active]
1157951009317	oxyanion strand; other site
1157951009318	catalytic triad [active]
1157951009319	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1157951009320	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951009321	active site
1157951009322	motif I; other site
1157951009323	motif II; other site
1157951009324	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1157951009325	putative active site pocket [active]
1157951009326	4-fold oligomerization interface [polypeptide binding]; other site
1157951009327	metal binding residues [ion binding]; metal-binding site
1157951009328	3-fold/trimer interface [polypeptide binding]; other site
1157951009329	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1157951009330	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951009331	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951009332	homodimer interface [polypeptide binding]; other site
1157951009333	catalytic residue [active]
1157951009334	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1157951009335	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1157951009336	NAD binding site [chemical binding]; other site
1157951009337	dimerization interface [polypeptide binding]; other site
1157951009338	product binding site; other site
1157951009339	substrate binding site [chemical binding]; other site
1157951009340	zinc binding site [ion binding]; other site
1157951009341	catalytic residues [active]
1157951009342	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1157951009343	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1157951009344	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1157951009345	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1157951009346	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1157951009347	putative NAD(P) binding site [chemical binding]; other site
1157951009348	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1157951009349	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1157951009350	putative C-terminal domain interface [polypeptide binding]; other site
1157951009351	putative GSH binding site (G-site) [chemical binding]; other site
1157951009352	putative dimer interface [polypeptide binding]; other site
1157951009353	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1157951009354	putative N-terminal domain interface [polypeptide binding]; other site
1157951009355	putative dimer interface [polypeptide binding]; other site
1157951009356	putative substrate binding pocket (H-site) [chemical binding]; other site
1157951009357	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1157951009358	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1157951009359	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1157951009360	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1157951009361	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1157951009362	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1157951009363	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1157951009364	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1157951009365	serine transporter; Region: stp; TIGR00814
1157951009366	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1157951009367	active site
1157951009368	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1157951009369	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
1157951009370	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1157951009371	GSH binding site [chemical binding]; other site
1157951009372	catalytic residues [active]
1157951009373	hypothetical protein; Provisional; Region: PRK10591
1157951009374	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1157951009375	23S rRNA methyluridine methyltransferase; Reviewed; Region: rumB; PRK03522
1157951009376	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951009377	S-adenosylmethionine binding site [chemical binding]; other site
1157951009378	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1157951009379	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951009380	dimer interface [polypeptide binding]; other site
1157951009381	conserved gate region; other site
1157951009382	putative PBP binding loops; other site
1157951009383	ABC-ATPase subunit interface; other site
1157951009384	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1157951009385	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951009386	dimer interface [polypeptide binding]; other site
1157951009387	conserved gate region; other site
1157951009388	putative PBP binding loops; other site
1157951009389	ABC-ATPase subunit interface; other site
1157951009390	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1157951009391	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1157951009392	substrate binding pocket [chemical binding]; other site
1157951009393	membrane-bound complex binding site; other site
1157951009394	hinge residues; other site
1157951009395	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1157951009396	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009397	Walker A/P-loop; other site
1157951009398	ATP binding site [chemical binding]; other site
1157951009399	Q-loop/lid; other site
1157951009400	ABC transporter signature motif; other site
1157951009401	Walker B; other site
1157951009402	D-loop; other site
1157951009403	H-loop/switch region; other site
1157951009404	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1157951009405	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1157951009406	putative NAD(P) binding site [chemical binding]; other site
1157951009407	putative active site [active]
1157951009408	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1157951009409	Predicted membrane protein [Function unknown]; Region: COG2431
1157951009410	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1157951009411	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1157951009412	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1157951009413	putative active site [active]
1157951009414	putative metal-binding site [ion binding]; other site
1157951009415	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1157951009416	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951009417	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951009418	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1157951009419	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1157951009420	Walker A/P-loop; other site
1157951009421	ATP binding site [chemical binding]; other site
1157951009422	Q-loop/lid; other site
1157951009423	ABC transporter signature motif; other site
1157951009424	Walker B; other site
1157951009425	D-loop; other site
1157951009426	H-loop/switch region; other site
1157951009427	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1157951009428	FtsX-like permease family; Region: FtsX; pfam02687
1157951009429	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1157951009430	Na binding site [ion binding]; other site
1157951009431	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1157951009432	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_6; cd07584
1157951009433	putative active site [active]
1157951009434	catalytic triad [active]
1157951009435	putative dimer interface [polypeptide binding]; other site
1157951009436	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1157951009437	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1157951009438	Bacterial transcriptional regulator; Region: IclR; pfam01614
1157951009439	Protein of unknown function (DUF1177); Region: DUF1177; pfam06675
1157951009440	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1157951009441	DNA-binding site [nucleotide binding]; DNA binding site
1157951009442	RNA-binding motif; other site
1157951009443	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1157951009444	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1157951009445	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951009446	Walker A motif; other site
1157951009447	ATP binding site [chemical binding]; other site
1157951009448	Walker B motif; other site
1157951009449	arginine finger; other site
1157951009450	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951009451	Walker A motif; other site
1157951009452	ATP binding site [chemical binding]; other site
1157951009453	Walker B motif; other site
1157951009454	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1157951009455	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1157951009456	rRNA binding site [nucleotide binding]; other site
1157951009457	predicted 30S ribosome binding site; other site
1157951009458	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1157951009459	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1157951009460	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951009461	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
1157951009462	Walker A/P-loop; other site
1157951009463	ATP binding site [chemical binding]; other site
1157951009464	Q-loop/lid; other site
1157951009465	ABC transporter signature motif; other site
1157951009466	Walker B; other site
1157951009467	D-loop; other site
1157951009468	H-loop/switch region; other site
1157951009469	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1157951009470	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951009471	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009472	Walker A/P-loop; other site
1157951009473	ATP binding site [chemical binding]; other site
1157951009474	Q-loop/lid; other site
1157951009475	ABC transporter signature motif; other site
1157951009476	Walker B; other site
1157951009477	D-loop; other site
1157951009478	H-loop/switch region; other site
1157951009479	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1157951009480	thioredoxin reductase; Provisional; Region: PRK10262
1157951009481	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1157951009482	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951009483	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1157951009484	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1157951009485	putative DNA binding site [nucleotide binding]; other site
1157951009486	putative Zn2+ binding site [ion binding]; other site
1157951009487	AsnC family; Region: AsnC_trans_reg; pfam01037
1157951009488	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1157951009489	DNA translocase FtsK; Provisional; Region: PRK10263
1157951009490	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1157951009491	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1157951009492	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1157951009493	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1157951009494	recombination factor protein RarA; Reviewed; Region: PRK13342
1157951009495	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951009496	Walker A motif; other site
1157951009497	ATP binding site [chemical binding]; other site
1157951009498	Walker B motif; other site
1157951009499	arginine finger; other site
1157951009500	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1157951009501	seryl-tRNA synthetase; Provisional; Region: PRK05431
1157951009502	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1157951009503	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1157951009504	dimer interface [polypeptide binding]; other site
1157951009505	active site
1157951009506	motif 1; other site
1157951009507	motif 2; other site
1157951009508	motif 3; other site
1157951009509	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1157951009510	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1157951009511	dimerization interface [polypeptide binding]; other site
1157951009512	putative DNA binding site [nucleotide binding]; other site
1157951009513	putative Zn2+ binding site [ion binding]; other site
1157951009514	AsnC family; Region: AsnC_trans_reg; pfam01037
1157951009515	Protein of unknown function (DUF2000); Region: DUF2000; cl02074
1157951009516	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1157951009517	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1157951009518	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951009519	FeS/SAM binding site; other site
1157951009520	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1157951009521	Pyruvate formate lyase 1; Region: PFL1; cd01678
1157951009522	coenzyme A binding site [chemical binding]; other site
1157951009523	active site
1157951009524	catalytic residues [active]
1157951009525	glycine loop; other site
1157951009526	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1157951009527	uncharacterized domain; Region: TIGR00702
1157951009528	YcaO-like family; Region: YcaO; pfam02624
1157951009529	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1157951009530	active site
1157951009531	homodimer interface [polypeptide binding]; other site
1157951009532	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1157951009533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951009534	outer membrane porin, OprD family; Region: OprD; pfam03573
1157951009535	Putative carbohydrate binding domain; Region: CHB_HEX; smart01081
1157951009536	N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]; Region: Chb; COG3525
1157951009537	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a...; Region: GH20_Sm-chitobiase-like; cd06569
1157951009538	active site
1157951009539	C-terminal Early set domain associated with the catalytic domain of chitobiase (also called N-acetylglucosaminidase); Region: E_set_Chitobiase_C; cd02847
1157951009540	ferric uptake regulator; Provisional; Region: fur; PRK09462
1157951009541	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1157951009542	metal binding site 2 [ion binding]; metal-binding site
1157951009543	putative DNA binding helix; other site
1157951009544	metal binding site 1 [ion binding]; metal-binding site
1157951009545	dimer interface [polypeptide binding]; other site
1157951009546	structural Zn2+ binding site [ion binding]; other site
1157951009547	flavodoxin FldA; Validated; Region: PRK09267
1157951009548	LexA regulated protein; Provisional; Region: PRK11675
1157951009549	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009550	H-loop/switch region; other site
1157951009551	integrase; Provisional; Region: int; PHA02601
1157951009552	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951009553	active site
1157951009554	DNA binding site [nucleotide binding]
1157951009555	Int/Topo IB signature motif; other site
1157951009556	MT-A70; Region: MT-A70; cl01947
1157951009557	Protein of unknown function (DUF2591); Region: DUF2591; cl11584
1157951009558	tRNA(guanine-26,N2-N2) methyltransferase; Region: TRM1; TIGR00308
1157951009559	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
1157951009560	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
1157951009561	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1157951009562	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1157951009563	dimer interface [polypeptide binding]; other site
1157951009564	ssDNA binding site [nucleotide binding]; other site
1157951009565	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1157951009566	phage nucleotide-binding protein; Region: phage_P_loop; TIGR01618
1157951009567	Protein of unknown function (DUF3024); Region: DUF3024; pfam11225
1157951009568	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1157951009569	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951009570	non-specific DNA binding site [nucleotide binding]; other site
1157951009571	salt bridge; other site
1157951009572	sequence-specific DNA binding site [nucleotide binding]; other site
1157951009573	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1157951009574	Catalytic site [active]
1157951009575	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951009576	non-specific DNA binding site [nucleotide binding]; other site
1157951009577	salt bridge; other site
1157951009578	sequence-specific DNA binding site [nucleotide binding]; other site
1157951009579	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713
1157951009580	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3645
1157951009581	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1157951009582	Replication protein P; Region: Phage_lambda_P; pfam06992
1157951009583	recombination associated protein; Reviewed; Region: rdgC; PRK00321
1157951009584	Protein of unknown function (DUF1192); Region: DUF1192; cl11573
1157951009585	Protein of unknown function (DUF551); Region: DUF551; pfam04448
1157951009586	hypothetical protein; Region: PHA00781
1157951009587	hypothetical protein; Provisional; Region: PRK09741
1157951009588	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
1157951009589	Endodeoxyribonuclease RusA; Region: RusA; cl01885
1157951009590	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1157951009591	Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106
1157951009592	virion protein; Provisional; Region: V; PHA02564
1157951009593	KilA-N domain; Region: KilA-N; pfam04383
1157951009594	ORF11CD3 domain; Region: ORF11CD3; pfam10549
1157951009595	Helix-turn-helix domain; Region: HTH_17; cl17695
1157951009596	Phage terminase large subunit; Region: Terminase_3; cl12054
1157951009597	Domain of unknown function (DUF4055); Region: DUF4055; pfam13264
1157951009598	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1157951009599	Bacteriophage related domain of unknown function; Region: DUF4128; pfam13554
1157951009600	Homeodomain-like domain; Region: HTH_23; cl17451
1157951009601	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1157951009602	TIGR04255 family protein; Region: sporadTIGR04255
1157951009603	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
1157951009604	tape measure domain; Region: tape_meas_nterm; TIGR02675
1157951009605	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
1157951009606	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
1157951009607	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1157951009608	Phage minor tail protein; Region: Phage_min_tail; pfam05939
1157951009609	Phage-related protein [Function unknown]; Region: gp18; COG4672
1157951009610	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1157951009611	MPN+ (JAMM) motif; other site
1157951009612	Zinc-binding site [ion binding]; other site
1157951009613	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1157951009614	NlpC/P60 family; Region: NLPC_P60; cl17555
1157951009615	Phage-related protein, tail component [Function unknown]; Region: COG4723
1157951009616	Phage-related protein, tail component [Function unknown]; Region: COG4733
1157951009617	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1157951009618	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1157951009619	Fibronectin type III protein; Region: DUF3672; pfam12421
1157951009620	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
1157951009621	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1157951009622	putative active site [active]
1157951009623	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951009624	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009625	Walker A/P-loop; other site
1157951009626	ATP binding site [chemical binding]; other site
1157951009627	Q-loop/lid; other site
1157951009628	ABC transporter signature motif; other site
1157951009629	Walker B; other site
1157951009630	D-loop; other site
1157951009631	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1157951009632	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951009633	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1157951009634	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
1157951009635	putative active site [active]
1157951009636	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951009637	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009638	Walker A/P-loop; other site
1157951009639	ATP binding site [chemical binding]; other site
1157951009640	Q-loop/lid; other site
1157951009641	ABC transporter signature motif; other site
1157951009642	Walker B; other site
1157951009643	D-loop; other site
1157951009644	H-loop/switch region; other site
1157951009645	acyl-CoA esterase; Provisional; Region: PRK10673
1157951009646	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cd00741
1157951009647	nucleophilic elbow; other site
1157951009648	catalytic triad; other site
1157951009649	replication initiation regulator SeqA; Provisional; Region: PRK11187
1157951009650	phosphoglucomutase; Validated; Region: PRK07564
1157951009651	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1157951009652	active site
1157951009653	substrate binding site [chemical binding]; other site
1157951009654	metal binding site [ion binding]; metal-binding site
1157951009655	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1157951009656	homodimer interface [polypeptide binding]; other site
1157951009657	substrate-cofactor binding pocket; other site
1157951009658	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951009659	catalytic residue [active]
1157951009660	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1157951009661	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1157951009662	hinge; other site
1157951009663	active site
1157951009664	cytidylate kinase; Provisional; Region: cmk; PRK00023
1157951009665	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1157951009666	CMP-binding site; other site
1157951009667	The sites determining sugar specificity; other site
1157951009668	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1157951009669	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1157951009670	RNA binding site [nucleotide binding]; other site
1157951009671	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1157951009672	RNA binding site [nucleotide binding]; other site
1157951009673	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1157951009674	RNA binding site [nucleotide binding]; other site
1157951009675	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1157951009676	RNA binding site [nucleotide binding]; other site
1157951009677	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1157951009678	RNA binding site [nucleotide binding]; other site
1157951009679	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1157951009680	RNA binding site [nucleotide binding]; other site
1157951009681	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1157951009682	IHF dimer interface [polypeptide binding]; other site
1157951009683	IHF - DNA interface [nucleotide binding]; other site
1157951009684	ComEC family competence protein; Provisional; Region: PRK11539
1157951009685	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1157951009686	Competence protein; Region: Competence; pfam03772
1157951009687	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1157951009688	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1157951009689	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1157951009690	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1157951009691	Walker A/P-loop; other site
1157951009692	ATP binding site [chemical binding]; other site
1157951009693	Q-loop/lid; other site
1157951009694	ABC transporter signature motif; other site
1157951009695	Walker B; other site
1157951009696	D-loop; other site
1157951009697	H-loop/switch region; other site
1157951009698	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1157951009699	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1157951009700	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1157951009701	DNA-binding site [nucleotide binding]; DNA binding site
1157951009702	RNA-binding motif; other site
1157951009703	Trm112p-like protein; Region: Trm112p; cl01066
1157951009704	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1157951009705	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1157951009706	Ligand binding site; other site
1157951009707	oligomer interface; other site
1157951009708	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1157951009709	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1157951009710	putative active site [active]
1157951009711	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1157951009712	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951009713	S-adenosylmethionine binding site [chemical binding]; other site
1157951009714	condesin subunit F; Provisional; Region: PRK05260
1157951009715	condesin subunit E; Provisional; Region: PRK05256
1157951009716	cell division protein MukB; Provisional; Region: mukB; PRK04863
1157951009717	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1157951009718	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1157951009719	acid phosphatase/phosphotransferase; Provisional; Region: aphA; PRK11009
1157951009720	murein L,D-transpeptidase; Provisional; Region: PRK10594
1157951009721	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1157951009722	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1157951009723	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1157951009724	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1157951009725	Peptidase M15; Region: Peptidase_M15_3; cl01194
1157951009726	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1157951009727	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1157951009728	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951009729	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951009730	homodimer interface [polypeptide binding]; other site
1157951009731	catalytic residue [active]
1157951009732	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1157951009733	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1157951009734	trimer interface [polypeptide binding]; other site
1157951009735	eyelet of channel; other site
1157951009736	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1157951009737	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1157951009738	putative dimer interface [polypeptide binding]; other site
1157951009739	putative anticodon binding site; other site
1157951009740	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1157951009741	homodimer interface [polypeptide binding]; other site
1157951009742	motif 1; other site
1157951009743	motif 2; other site
1157951009744	active site
1157951009745	motif 3; other site
1157951009746	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1157951009747	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1157951009748	active site
1157951009749	aminopeptidase N; Provisional; Region: pepN; PRK14015
1157951009750	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1157951009751	active site
1157951009752	Zn binding site [ion binding]; other site
1157951009753	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1157951009754	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1157951009755	quinone interaction residues [chemical binding]; other site
1157951009756	active site
1157951009757	catalytic residues [active]
1157951009758	FMN binding site [chemical binding]; other site
1157951009759	substrate binding site [chemical binding]; other site
1157951009760	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1157951009761	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1157951009762	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1157951009763	MOSC domain; Region: MOSC; pfam03473
1157951009764	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1157951009765	catalytic loop [active]
1157951009766	iron binding site [ion binding]; other site
1157951009767	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1157951009768	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1157951009769	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1157951009770	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951009771	S-adenosylmethionine binding site [chemical binding]; other site
1157951009772	ABC transporter ATPase component; Reviewed; Region: PRK11147
1157951009773	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009774	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1157951009775	Walker A/P-loop; other site
1157951009776	Walker A/P-loop; other site
1157951009777	ATP binding site [chemical binding]; other site
1157951009778	ATP binding site [chemical binding]; other site
1157951009779	Q-loop/lid; other site
1157951009780	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951009781	ABC transporter signature motif; other site
1157951009782	Walker B; other site
1157951009783	ABC transporter; Region: ABC_tran_2; pfam12848
1157951009784	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951009785	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1157951009786	Paraquat-inducible protein A; Region: PqiA; pfam04403
1157951009787	Paraquat-inducible protein A; Region: PqiA; pfam04403
1157951009788	paraquat-inducible protein B; Provisional; Region: PRK10807
1157951009789	mce related protein; Region: MCE; pfam02470
1157951009790	mce related protein; Region: MCE; pfam02470
1157951009791	mce related protein; Region: MCE; pfam02470
1157951009792	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1157951009793	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1157951009794	Ribosome modulation factor; Region: RMF; pfam04957
1157951009795	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1157951009796	active site 1 [active]
1157951009797	dimer interface [polypeptide binding]; other site
1157951009798	active site 2 [active]
1157951009799	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1157951009800	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1157951009801	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1157951009802	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1157951009803	outer membrane protein A; Reviewed; Region: PRK10808
1157951009804	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1157951009805	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1157951009806	ligand binding site [chemical binding]; other site
1157951009807	SOS cell division inhibitor; Provisional; Region: PRK10595
1157951009808	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1157951009809	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1157951009810	TIGR01666 family membrane protein; Region: YCCS
1157951009811	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1157951009812	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1157951009813	DNA helicase IV; Provisional; Region: helD; PRK11054
1157951009814	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1157951009815	Part of AAA domain; Region: AAA_19; pfam13245
1157951009816	Family description; Region: UvrD_C_2; pfam13538
1157951009817	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1157951009818	active site
1157951009819	dimer interfaces [polypeptide binding]; other site
1157951009820	catalytic residues [active]
1157951009821	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1157951009822	heat shock protein HspQ; Provisional; Region: PRK14129
1157951009823	Acylphosphatase; Region: Acylphosphatase; pfam00708
1157951009824	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1157951009825	sulfur relay protein, TusE/DsrC/DsvC family; Region: dsrC_tusE_dsvC; TIGR03342
1157951009826	integrase; Provisional; Region: PRK09692
1157951009827	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1157951009828	active site
1157951009829	Int/Topo IB signature motif; other site
1157951009830	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1157951009831	AntA/AntB antirepressor; Region: AntA; pfam08346
1157951009832	Ash protein family; Region: Phage_ASH; pfam10554
1157951009833	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
1157951009834	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
1157951009835	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1157951009836	active site
1157951009837	metal binding site [ion binding]; metal-binding site
1157951009838	interdomain interaction site; other site
1157951009839	D5 N terminal like; Region: D5_N; smart00885
1157951009840	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
1157951009841	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
1157951009842	Competence protein CoiA-like family; Region: CoiA; cl11541
1157951009843	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cl15270
1157951009844	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951009845	active site
1157951009846	Int/Topo IB signature motif; other site
1157951009847	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951009848	active site
1157951009849	DNA binding site [nucleotide binding]
1157951009850	Int/Topo IB signature motif; other site
1157951009851	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951009852	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951009853	non-specific DNA binding site [nucleotide binding]; other site
1157951009854	salt bridge; other site
1157951009855	sequence-specific DNA binding site [nucleotide binding]; other site
1157951009856	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951009857	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951009858	non-specific DNA binding site [nucleotide binding]; other site
1157951009859	salt bridge; other site
1157951009860	sequence-specific DNA binding site [nucleotide binding]; other site
1157951009861	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951009862	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951009863	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1157951009864	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951009865	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951009866	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951009867	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951009868	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951009869	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951009870	Fimbrial protein; Region: Fimbrial; cl01416
1157951009871	Fimbrial protein; Region: Fimbrial; pfam00419
1157951009872	Fimbrial protein; Region: Fimbrial; pfam00419
1157951009873	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951009874	Uncharacterized protein conserved in bacteria (DUF2251); Region: DUF2251; pfam10008
1157951009875	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1157951009876	DNA-J related protein; Region: DNAJ_related; pfam12339
1157951009877	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
1157951009878	Repair protein; Region: Repair_PSII; pfam04536
1157951009879	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1157951009880	amino acid carrier protein; Region: agcS; TIGR00835
1157951009881	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1157951009882	Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301
1157951009883	putative ligand binding site [chemical binding]; other site
1157951009884	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1157951009885	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1157951009886	TM-ABC transporter signature motif; other site
1157951009887	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1157951009888	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1157951009889	Walker A/P-loop; other site
1157951009890	ATP binding site [chemical binding]; other site
1157951009891	Q-loop/lid; other site
1157951009892	ABC transporter signature motif; other site
1157951009893	Walker B; other site
1157951009894	D-loop; other site
1157951009895	H-loop/switch region; other site
1157951009896	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1157951009897	D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_1; cd07809
1157951009898	N- and C-terminal domain interface [polypeptide binding]; other site
1157951009899	D-xylulose kinase; Region: XylB; TIGR01312
1157951009900	active site
1157951009901	MgATP binding site [chemical binding]; other site
1157951009902	catalytic site [active]
1157951009903	metal binding site [ion binding]; metal-binding site
1157951009904	xylulose binding site [chemical binding]; other site
1157951009905	putative homodimer interface [polypeptide binding]; other site
1157951009906	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
1157951009907	L-idonate 5-dehydrogenase; Region: PLN02702
1157951009908	inhibitor binding site; inhibition site
1157951009909	catalytic Zn binding site [ion binding]; other site
1157951009910	structural Zn binding site [ion binding]; other site
1157951009911	NADP binding site [chemical binding]; other site
1157951009912	tetramer interface [polypeptide binding]; other site
1157951009913	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
1157951009914	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1157951009915	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951009916	DNA binding site [nucleotide binding]
1157951009917	domain linker motif; other site
1157951009918	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1157951009919	dimerization interface [polypeptide binding]; other site
1157951009920	ligand binding site [chemical binding]; other site
1157951009921	YcxB-like protein; Region: YcxB; pfam14317
1157951009922	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951009923	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1157951009924	Coenzyme A binding pocket [chemical binding]; other site
1157951009925	Protein of unknown function (DUF2798); Region: DUF2798; pfam11391
1157951009926	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1157951009927	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951009928	DNA binding site [nucleotide binding]
1157951009929	domain linker motif; other site
1157951009930	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1157951009931	dimerization interface (closed form) [polypeptide binding]; other site
1157951009932	ligand binding site [chemical binding]; other site
1157951009933	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
1157951009934	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1157951009935	active site turn [active]
1157951009936	phosphorylation site [posttranslational modification]
1157951009937	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1157951009938	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1157951009939	beta-galactosidase; Region: BGL; TIGR03356
1157951009940	Predicted membrane protein [Function unknown]; Region: COG4125
1157951009941	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1157951009942	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1157951009943	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951009944	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951009945	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1157951009946	dimerization interface [polypeptide binding]; other site
1157951009947	hypothetical protein; Provisional; Region: PRK02237
1157951009948	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951009949	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951009950	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951009951	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1157951009952	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1157951009953	molybdopterin cofactor binding site; other site
1157951009954	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1157951009955	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1157951009956	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1157951009957	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1157951009958	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1157951009959	putative deacylase active site [active]
1157951009960	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1157951009961	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1157951009962	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1157951009963	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951009964	Coenzyme A binding pocket [chemical binding]; other site
1157951009965	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1157951009966	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1157951009967	catalytic core [active]
1157951009968	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1157951009969	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1157951009970	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1157951009971	Ligand Binding Site [chemical binding]; other site
1157951009972	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951009973	Sel1 repeat; Region: Sel1; cl02723
1157951009974	Sel1-like repeats; Region: SEL1; smart00671
1157951009975	Sel1-like repeats; Region: SEL1; smart00671
1157951009976	Sel1-like repeats; Region: SEL1; smart00671
1157951009977	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
1157951009978	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1157951009979	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951009980	Walker A motif; other site
1157951009981	ATP binding site [chemical binding]; other site
1157951009982	Walker B motif; other site
1157951009983	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1157951009984	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
1157951009985	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
1157951009986	multimer interface [polypeptide binding]; other site
1157951009987	active site
1157951009988	catalytic triad [active]
1157951009989	dimer interface [polypeptide binding]; other site
1157951009990	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1157951009991	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1157951009992	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1157951009993	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951009994	putative substrate translocation pore; other site
1157951009995	POT family; Region: PTR2; cl17359
1157951009996	drug efflux system protein MdtG; Provisional; Region: PRK09874
1157951009997	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951009998	putative substrate translocation pore; other site
1157951009999	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1157951010000	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1157951010001	putative acyl-acceptor binding pocket; other site
1157951010002	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1157951010003	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951010004	active site
1157951010005	phosphorylation site [posttranslational modification]
1157951010006	intermolecular recognition site; other site
1157951010007	dimerization interface [polypeptide binding]; other site
1157951010008	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1157951010009	DNA binding residues [nucleotide binding]
1157951010010	dimerization interface [polypeptide binding]; other site
1157951010011	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1157951010012	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1157951010013	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1157951010014	dimer interface [polypeptide binding]; other site
1157951010015	phosphorylation site [posttranslational modification]
1157951010016	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951010017	ATP binding site [chemical binding]; other site
1157951010018	G-X-G motif; other site
1157951010019	tetrathionate reductase subunit B; Provisional; Region: PRK14993
1157951010020	4Fe-4S binding domain; Region: Fer4; pfam00037
1157951010021	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1157951010022	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1157951010023	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1157951010024	molybdopterin cofactor binding site; other site
1157951010025	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1157951010026	putative molybdopterin cofactor binding site [chemical binding]; other site
1157951010027	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1157951010028	putative molybdopterin cofactor binding site; other site
1157951010029	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1157951010030	Protein of unknown function (DUF1007); Region: DUF1007; cl01487
1157951010031	Protein of unknown function (DUF1007); Region: DUF1007; cl01487
1157951010032	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1157951010033	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1157951010034	active site residue [active]
1157951010035	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1157951010036	DNA binding residues [nucleotide binding]
1157951010037	dimerization interface [polypeptide binding]; other site
1157951010038	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1157951010039	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1157951010040	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1157951010041	active site
1157951010042	substrate binding pocket [chemical binding]; other site
1157951010043	dimer interface [polypeptide binding]; other site
1157951010044	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1157951010045	Sulfatase; Region: Sulfatase; pfam00884
1157951010046	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1157951010047	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951010048	FeS/SAM binding site; other site
1157951010049	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1157951010050	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1157951010051	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1157951010052	DNA-binding site [nucleotide binding]; DNA binding site
1157951010053	RNA-binding motif; other site
1157951010054	Dextransucrase DSRB; Region: DSRB; cl11680
1157951010055	magnesium transport protein MgtC; Provisional; Region: PRK15385
1157951010056	MgtC family; Region: MgtC; pfam02308
1157951010057	magnesium-transporting ATPase; Provisional; Region: PRK15122
1157951010058	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1157951010059	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1157951010060	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1157951010061	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951010062	motif II; other site
1157951010063	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1157951010064	IpaB/EvcA family; Region: IpaB_EvcA; pfam03278
1157951010065	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
1157951010066	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1157951010067	Predicted transcriptional regulator [Transcription]; Region: COG3905
1157951010068	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1157951010069	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1157951010070	Glutamate binding site [chemical binding]; other site
1157951010071	NAD binding site [chemical binding]; other site
1157951010072	catalytic residues [active]
1157951010073	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1157951010074	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1157951010075	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1157951010076	Na binding site [ion binding]; other site
1157951010077	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1157951010078	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1157951010079	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1157951010080	N-terminal domain interface [polypeptide binding]; other site
1157951010081	dimer interface [polypeptide binding]; other site
1157951010082	substrate binding pocket (H-site) [chemical binding]; other site
1157951010083	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1157951010084	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1157951010085	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1157951010086	oligomer interface [polypeptide binding]; other site
1157951010087	active site
1157951010088	metal binding site [ion binding]; metal-binding site
1157951010089	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1157951010090	active site
1157951010091	P-loop; other site
1157951010092	phosphorylation site [posttranslational modification]
1157951010093	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1157951010094	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1157951010095	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
1157951010096	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1157951010097	active site
1157951010098	phosphorylation site [posttranslational modification]
1157951010099	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1157951010100	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1157951010101	substrate binding site [chemical binding]; other site
1157951010102	hexamer interface [polypeptide binding]; other site
1157951010103	metal binding site [ion binding]; metal-binding site
1157951010104	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1157951010105	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1157951010106	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1157951010107	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951010108	non-specific DNA binding site [nucleotide binding]; other site
1157951010109	salt bridge; other site
1157951010110	sequence-specific DNA binding site [nucleotide binding]; other site
1157951010111	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
1157951010112	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1157951010113	IS2 transposase TnpB; Reviewed; Region: PRK09409
1157951010114	Integrase core domain; Region: rve; pfam00665
1157951010115	Integrase core domain; Region: rve_3; pfam13683
1157951010116	Transposase; Region: HTH_Tnp_1; pfam01527
1157951010117	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it, thus inhibiting its potentially lethal RNase activity inside the...; Region: Barstar_like; cl01048
1157951010118	RNAase interaction site [polypeptide binding]; other site
1157951010119	microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential  for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th,  Pb, N1, and Ms) and...; Region: microbial_RNases; cl00212
1157951010120	active site
1157951010121	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1157951010122	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951010123	Domain of unknown function (DUF4291); Region: DUF4291; pfam14124
1157951010124	HEAT repeats; Region: HEAT_2; pfam13646
1157951010125	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
1157951010126	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it, thus inhibiting its potentially lethal RNase activity inside the...; Region: Barstar_like; cl01048
1157951010127	RNAase interaction site [polypeptide binding]; other site
1157951010128	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951010129	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1157951010130	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1157951010131	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1157951010132	RHS Repeat; Region: RHS_repeat; pfam05593
1157951010133	RHS Repeat; Region: RHS_repeat; pfam05593
1157951010134	RHS Repeat; Region: RHS_repeat; pfam05593
1157951010135	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1157951010136	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951010137	Domain of unknown function (DUF4150); Region: DUF4150; pfam13665
1157951010138	Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; pfam09937
1157951010139	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1157951010140	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1157951010141	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1157951010142	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1157951010143	Spore Coat Protein U domain; Region: SCPU; pfam05229
1157951010144	Uncharacterized secreted protein [Function unknown]; Region: COG5430
1157951010145	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951010146	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951010147	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951010148	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951010149	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951010150	Spore Coat Protein U domain; Region: SCPU; cl02253
1157951010151	transcriptional activator FlhD; Provisional; Region: PRK02909
1157951010152	transcriptional activator FlhC; Provisional; Region: PRK12722
1157951010153	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1157951010154	flagellar motor protein MotA; Validated; Region: PRK09110
1157951010155	flagellar motor protein MotB; Validated; Region: motB; PRK09041
1157951010156	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1157951010157	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1157951010158	ligand binding site [chemical binding]; other site
1157951010159	chemotaxis protein CheA; Provisional; Region: PRK10547
1157951010160	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1157951010161	putative binding surface; other site
1157951010162	active site
1157951010163	CheY binding; Region: CheY-binding; pfam09078
1157951010164	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1157951010165	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951010166	ATP binding site [chemical binding]; other site
1157951010167	Mg2+ binding site [ion binding]; other site
1157951010168	G-X-G motif; other site
1157951010169	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1157951010170	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
1157951010171	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1157951010172	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1157951010173	dimer interface [polypeptide binding]; other site
1157951010174	ligand binding site [chemical binding]; other site
1157951010175	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1157951010176	dimerization interface [polypeptide binding]; other site
1157951010177	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1157951010178	dimer interface [polypeptide binding]; other site
1157951010179	putative CheW interface [polypeptide binding]; other site
1157951010180	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1157951010181	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1157951010182	dimer interface [polypeptide binding]; other site
1157951010183	ligand binding site [chemical binding]; other site
1157951010184	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1157951010185	dimerization interface [polypeptide binding]; other site
1157951010186	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1157951010187	dimer interface [polypeptide binding]; other site
1157951010188	putative CheW interface [polypeptide binding]; other site
1157951010189	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1157951010190	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1157951010191	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951010192	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1157951010193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951010194	active site
1157951010195	phosphorylation site [posttranslational modification]
1157951010196	intermolecular recognition site; other site
1157951010197	dimerization interface [polypeptide binding]; other site
1157951010198	CheB methylesterase; Region: CheB_methylest; pfam01339
1157951010199	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1157951010200	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951010201	active site
1157951010202	phosphorylation site [posttranslational modification]
1157951010203	intermolecular recognition site; other site
1157951010204	dimerization interface [polypeptide binding]; other site
1157951010205	Chemotaxis phosphatase, CheZ; Region: CheZ; cl01219
1157951010206	Chemotaxis phosphatase, CheZ; Region: CheZ; cl01219
1157951010207	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1157951010208	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1157951010209	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1157951010210	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1157951010211	FHIPEP family; Region: FHIPEP; pfam00771
1157951010212	FlgN protein; Region: FlgN; cl09176
1157951010213	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
1157951010214	SAF-like; Region: SAF_2; pfam13144
1157951010215	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1157951010216	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1157951010217	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1157951010218	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1157951010219	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1157951010220	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1157951010221	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1157951010222	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1157951010223	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1157951010224	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1157951010225	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1157951010226	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1157951010227	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1157951010228	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1157951010229	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1157951010230	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
1157951010231	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1157951010232	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1157951010233	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1157951010234	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1157951010235	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1157951010236	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12698
1157951010237	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1157951010238	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1157951010239	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1157951010240	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1157951010241	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1157951010242	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1157951010243	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1157951010244	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1157951010245	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1157951010246	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1157951010247	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1157951010248	DinI-like family; Region: DinI; cl11630
1157951010249	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1157951010250	Integrase core domain; Region: rve; pfam00665
1157951010251	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
1157951010252	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
1157951010253	CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673
1157951010254	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cl09829
1157951010255	CRISPR/Cas system-associated RAMP superfamily protein Csy2; Region: Csy2_I-F; cd09736
1157951010256	CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cd09737
1157951010257	CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cd09739
1157951010258	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1157951010259	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1157951010260	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1157951010261	Flagellar biosynthesis protein, FliO; Region: FliO; cl01247
1157951010262	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
1157951010263	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1157951010264	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1157951010265	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1157951010266	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
1157951010267	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1157951010268	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1157951010269	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1157951010270	Walker A motif/ATP binding site; other site
1157951010271	Walker B motif; other site
1157951010272	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1157951010273	Flagellar assembly protein FliH; Region: FliH; pfam02108
1157951010274	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1157951010275	FliG C-terminal domain; Region: FliG_C; pfam01706
1157951010276	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1157951010277	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1157951010278	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1157951010279	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1157951010280	YadA-like C-terminal region; Region: YadA; pfam03895
1157951010281	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1157951010282	active site
1157951010283	catalytic residues [active]
1157951010284	metal binding site [ion binding]; metal-binding site
1157951010285	Flagellar protein FliT; Region: FliT; cl05125
1157951010286	flagellar protein FliS; Validated; Region: fliS; PRK05685
1157951010287	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1157951010288	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1157951010289	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1157951010290	flagellin; Validated; Region: PRK06819
1157951010291	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1157951010292	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1157951010293	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1157951010294	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1157951010295	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1157951010296	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1157951010297	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1157951010298	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1157951010299	active site
1157951010300	intersubunit interface [polypeptide binding]; other site
1157951010301	catalytic residue [active]
1157951010302	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1157951010303	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1157951010304	substrate binding site [chemical binding]; other site
1157951010305	ATP binding site [chemical binding]; other site
1157951010306	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1157951010307	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1157951010308	Bacterial transcriptional regulator; Region: IclR; pfam01614
1157951010309	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain.  Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543
1157951010310	active site
1157951010311	choline transport protein BetT; Provisional; Region: PRK09928
1157951010312	transcriptional regulator BetI; Validated; Region: PRK00767
1157951010313	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951010314	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1157951010315	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
1157951010316	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
1157951010317	tetrameric interface [polypeptide binding]; other site
1157951010318	NAD binding site [chemical binding]; other site
1157951010319	catalytic residues [active]
1157951010320	choline dehydrogenase; Validated; Region: PRK02106
1157951010321	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1157951010322	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
1157951010323	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1157951010324	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1157951010325	transmembrane helices; other site
1157951010326	EamA-like transporter family; Region: EamA; pfam00892
1157951010327	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1157951010328	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1157951010329	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1157951010330	active site
1157951010331	FMN binding site [chemical binding]; other site
1157951010332	substrate binding site [chemical binding]; other site
1157951010333	homotetramer interface [polypeptide binding]; other site
1157951010334	catalytic residue [active]
1157951010335	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
1157951010336	Citrate transporter; Region: CitMHS; pfam03600
1157951010337	RNA ligase; Region: RNA_ligase; pfam09414
1157951010338	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1157951010339	Zn2+ binding site [ion binding]; other site
1157951010340	Mg2+ binding site [ion binding]; other site
1157951010341	AAA domain; Region: AAA_33; pfam13671
1157951010342	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
1157951010343	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1157951010344	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1157951010345	transmembrane helices; other site
1157951010346	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
1157951010347	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
1157951010348	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1157951010349	Coenzyme A transferase; Region: CoA_trans; cl17247
1157951010350	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1157951010351	Malonate decarboxylase delta subunit (MdcD); Region: ACP; cl06082
1157951010352	Citrate lyase ligase C-terminal domain; Region: Citrate_ly_lig; smart00764
1157951010353	active site
1157951010354	nucleotide binding site [chemical binding]; other site
1157951010355	HIGH motif; other site
1157951010356	KMSKS motif; other site
1157951010357	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1157951010358	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1157951010359	PAS domain; Region: PAS; smart00091
1157951010360	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1157951010361	ATP binding site [chemical binding]; other site
1157951010362	Mg2+ binding site [ion binding]; other site
1157951010363	G-X-G motif; other site
1157951010364	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1157951010365	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1157951010366	active site
1157951010367	phosphorylation site [posttranslational modification]
1157951010368	intermolecular recognition site; other site
1157951010369	dimerization interface [polypeptide binding]; other site
1157951010370	Transcriptional regulator; Region: CitT; pfam12431
1157951010371	Sel1-like repeats; Region: SEL1; smart00671
1157951010372	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1157951010373	Sel1-like repeats; Region: SEL1; smart00671
1157951010374	Sel1-like repeats; Region: SEL1; smart00671
1157951010375	Sel1-like repeats; Region: SEL1; smart00671
1157951010376	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1157951010377	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951010378	putative substrate translocation pore; other site
1157951010379	POT family; Region: PTR2; pfam00854
1157951010380	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1157951010381	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1157951010382	putative active site [active]
1157951010383	Membrane transport protein; Region: Mem_trans; cl09117
1157951010384	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
1157951010385	Protein of unknown function (DUF3999); Region: DUF3999; pfam13163
1157951010386	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1157951010387	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1157951010388	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
1157951010389	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1157951010390	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1157951010391	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1157951010392	metal binding site [ion binding]; metal-binding site
1157951010393	dimer interface [polypeptide binding]; other site
1157951010394	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1157951010395	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1157951010396	DNA binding residues [nucleotide binding]
1157951010397	dimerization interface [polypeptide binding]; other site
1157951010398	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1157951010399	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1157951010400	GIY-YIG motif/motif A; other site
1157951010401	active site
1157951010402	catalytic site [active]
1157951010403	putative DNA binding site [nucleotide binding]; other site
1157951010404	metal binding site [ion binding]; metal-binding site
1157951010405	UvrB/uvrC motif; Region: UVR; pfam02151
1157951010406	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1157951010407	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1157951010408	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951010409	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951010410	active site
1157951010411	DNA binding site [nucleotide binding]
1157951010412	Int/Topo IB signature motif; other site
1157951010413	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
1157951010414	HNH endonuclease; Region: HNH_3; pfam13392
1157951010415	Siphovirus Gp157; Region: Sipho_Gp157; pfam05565
1157951010416	exonuclease VIII; Reviewed; Region: PRK09709
1157951010417	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951010418	non-specific DNA binding site [nucleotide binding]; other site
1157951010419	salt bridge; other site
1157951010420	Predicted transcriptional regulator [Transcription]; Region: COG2932
1157951010421	sequence-specific DNA binding site [nucleotide binding]; other site
1157951010422	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1157951010423	Catalytic site [active]
1157951010424	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1157951010425	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1157951010426	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1157951010427	phage replicative helicase, DnaB family, HK022 subfamily; Region: phage_DnaB; TIGR03600
1157951010428	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1157951010429	Walker A motif; other site
1157951010430	ATP binding site [chemical binding]; other site
1157951010431	Walker B motif; other site
1157951010432	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
1157951010433	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1157951010434	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1157951010435	Antitermination protein; Region: Antiterm; pfam03589
1157951010436	Antitermination protein; Region: Antiterm; pfam03589
1157951010437	glycerol kinase; Region: glycerol_kin; TIGR01311
1157951010438	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1157951010439	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1157951010440	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1157951010441	Terminase small subunit; Region: Terminase_2; pfam03592
1157951010442	YcxB-like protein; Region: YcxB; pfam14317
1157951010443	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1157951010444	active site
1157951010445	metal binding site [ion binding]; metal-binding site
1157951010446	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1157951010447	CAAX protease self-immunity; Region: Abi; pfam02517
1157951010448	Putative amidotransferase; Region: DUF4066; pfam13278
1157951010449	conserved cys residue [active]
1157951010450	GH18 domain of Chitinase D (ChiD).  ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins.  The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18; Region: GH18_chitinase_D-like; cd02871
1157951010451	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
1157951010452	putative active site [active]
1157951010453	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1157951010454	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1157951010455	Switch II region; other site
1157951010456	G4 box; other site
1157951010457	HEAT repeats; Region: HEAT_2; pfam13646
1157951010458	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1157951010459	Sulfatase; Region: Sulfatase; cl17466
1157951010460	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1157951010461	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
1157951010462	Domain of unknown function (DUF305); Region: DUF305; cl17794
1157951010463	Transferrin binding protein-like solute binding protein; Region: Lipoprotein_5; pfam01298
1157951010464	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1157951010465	binding surface
1157951010466	TPR motif; other site
1157951010467	Protein of unknown function (DUF560); Region: DUF560; pfam04575
1157951010468	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1157951010469	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1157951010470	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1157951010471	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1157951010472	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1157951010473	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1157951010474	hypothetical protein; Provisional; Region: PRK07064
1157951010475	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1157951010476	PYR/PP interface [polypeptide binding]; other site
1157951010477	dimer interface [polypeptide binding]; other site
1157951010478	TPP binding site [chemical binding]; other site
1157951010479	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951010480	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
1157951010481	TPP-binding site [chemical binding]; other site
1157951010482	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1157951010483	Uncharacterized Candidatus pelagibacter aldehyde dehydrogenase, DhaS-like; Region: ALDH_DhaS; cd07114
1157951010484	NAD(P) binding site [chemical binding]; other site
1157951010485	catalytic residues [active]
1157951010486	L-aspartate dehydrogenase; Provisional; Region: PRK13303
1157951010487	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1157951010488	Domain of unknown function DUF108; Region: DUF108; pfam01958
1157951010489	short chain dehydrogenase; Provisional; Region: PRK07062
1157951010490	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344
1157951010491	putative NAD(P) binding site [chemical binding]; other site
1157951010492	putative active site [active]
1157951010493	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1157951010494	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1157951010495	nucleophilic elbow; other site
1157951010496	catalytic triad; other site
1157951010497	Cupin domain; Region: Cupin_2; pfam07883
1157951010498	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951010499	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1157951010500	putative substrate translocation pore; other site
1157951010501	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
1157951010502	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951010503	C-terminal domain of Burkholderia sp. NF100 MhqB and similar proteins; MhqB is a type I extradiol dioxygenase involved in the catabolism of methylhydroquinone, an intermediate in the degradation of fenitrothion; Region: MhqB_like_C; cd08360
1157951010504	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1157951010505	putative active site [active]
1157951010506	putative metal binding site [ion binding]; other site
1157951010507	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1157951010508	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1157951010509	Bacterial transcriptional regulator; Region: IclR; pfam01614
1157951010510	short chain dehydrogenase; Provisional; Region: PRK12939
1157951010511	classical (c) SDRs; Region: SDR_c; cd05233
1157951010512	NAD(P) binding site [chemical binding]; other site
1157951010513	active site
1157951010514	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1157951010515	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1157951010516	[2Fe-2S] cluster binding site [ion binding]; other site
1157951010517	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1157951010518	hydrophobic ligand binding site; other site
1157951010519	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
1157951010520	[2Fe-2S] cluster binding site [ion binding]; other site
1157951010521	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1157951010522	Ligand Binding Site [chemical binding]; other site
1157951010523	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
1157951010524	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1157951010525	active site
1157951010526	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951010527	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951010528	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1157951010529	putative effector binding pocket; other site
1157951010530	dimerization interface [polypeptide binding]; other site
1157951010531	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1157951010532	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1157951010533	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1157951010534	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1157951010535	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951010536	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1157951010537	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1157951010538	active site
1157951010539	P-loop; other site
1157951010540	phosphorylation site [posttranslational modification]
1157951010541	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1157951010542	active site
1157951010543	phosphorylation site [posttranslational modification]
1157951010544	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1157951010545	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951010546	DNA binding site [nucleotide binding]
1157951010547	domain linker motif; other site
1157951010548	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1157951010549	Uncharacterized protein family (UPF0257); Region: UPF0257; cl14672
1157951010550	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1157951010551	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1157951010552	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1157951010553	Walker A/P-loop; other site
1157951010554	ATP binding site [chemical binding]; other site
1157951010555	Q-loop/lid; other site
1157951010556	ABC transporter signature motif; other site
1157951010557	Walker B; other site
1157951010558	D-loop; other site
1157951010559	H-loop/switch region; other site
1157951010560	chromosome condensation membrane protein; Provisional; Region: PRK14196
1157951010561	allantoate amidohydrolase; Reviewed; Region: PRK09290
1157951010562	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1157951010563	active site
1157951010564	metal binding site [ion binding]; metal-binding site
1157951010565	dimer interface [polypeptide binding]; other site
1157951010566	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1157951010567	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_subfamily5; cd08019
1157951010568	metal binding site [ion binding]; metal-binding site
1157951010569	putative dimer interface [polypeptide binding]; other site
1157951010570	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1157951010571	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951010572	non-specific DNA binding site [nucleotide binding]; other site
1157951010573	salt bridge; other site
1157951010574	sequence-specific DNA binding site [nucleotide binding]; other site
1157951010575	AzlC protein; Region: AzlC; pfam03591
1157951010576	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1157951010577	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1157951010578	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
1157951010579	hypothetical protein; Provisional; Region: PRK10508
1157951010580	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1157951010581	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1157951010582	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1157951010583	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1157951010584	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; cl00868
1157951010585	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1157951010586	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1157951010587	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1157951010588	motif II; other site
1157951010589	YniB-like protein; Region: YniB; pfam14002
1157951010590	Fructosamine kinase; Region: Fructosamin_kin; pfam03881
1157951010591	Phosphotransferase enzyme family; Region: APH; pfam01636
1157951010592	putative oxidoreductase; Provisional; Region: PRK09939
1157951010593	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1157951010594	putative molybdopterin cofactor binding site [chemical binding]; other site
1157951010595	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1157951010596	putative molybdopterin cofactor binding site; other site
1157951010597	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1157951010598	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951010599	ABC-ATPase subunit  interface; other site
1157951010600	dimer interface [polypeptide binding]; other site
1157951010601	putative PBP binding regions; other site
1157951010602	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1157951010603	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951010604	ABC-ATPase subunit  interface; other site
1157951010605	dimer interface [polypeptide binding]; other site
1157951010606	putative PBP binding regions; other site
1157951010607	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1157951010608	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1157951010609	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1157951010610	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1157951010611	metal binding site [ion binding]; metal-binding site
1157951010612	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1157951010613	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1157951010614	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1157951010615	catalytic residue [active]
1157951010616	inner membrane protein; Provisional; Region: PRK10995
1157951010617	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
1157951010618	FosA, a Fosfomycin resistance protein, catalyzes the addition of glutathione to the antibiotic fosfomycin, making it inactive; Region: FosA; cd07244
1157951010619	dimer interface [polypeptide binding]; other site
1157951010620	Mn binding site [ion binding]; other site
1157951010621	K binding site [ion binding]; other site
1157951010622	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951010623	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1157951010624	Coenzyme A binding pocket [chemical binding]; other site
1157951010625	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1157951010626	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1157951010627	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1157951010628	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1157951010629	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1157951010630	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1157951010631	active site
1157951010632	dimer interface [polypeptide binding]; other site
1157951010633	motif 1; other site
1157951010634	motif 2; other site
1157951010635	motif 3; other site
1157951010636	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1157951010637	anticodon binding site; other site
1157951010638	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1157951010639	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1157951010640	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1157951010641	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1157951010642	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1157951010643	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1157951010644	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1157951010645	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1157951010646	23S rRNA binding site [nucleotide binding]; other site
1157951010647	L21 binding site [polypeptide binding]; other site
1157951010648	L13 binding site [polypeptide binding]; other site
1157951010649	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1157951010650	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1157951010651	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1157951010652	dimer interface [polypeptide binding]; other site
1157951010653	motif 1; other site
1157951010654	active site
1157951010655	motif 2; other site
1157951010656	motif 3; other site
1157951010657	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1157951010658	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1157951010659	putative tRNA-binding site [nucleotide binding]; other site
1157951010660	B3/4 domain; Region: B3_4; pfam03483
1157951010661	tRNA synthetase B5 domain; Region: B5; smart00874
1157951010662	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1157951010663	dimer interface [polypeptide binding]; other site
1157951010664	motif 1; other site
1157951010665	motif 3; other site
1157951010666	motif 2; other site
1157951010667	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1157951010668	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1157951010669	IHF dimer interface [polypeptide binding]; other site
1157951010670	IHF - DNA interface [nucleotide binding]; other site
1157951010671	RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; Region: RhoGAP; cd00159
1157951010672	GTPase interaction site; other site
1157951010673	catalytic residue [active]
1157951010674	RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; Region: RhoGAP; cl02570
1157951010675	GTPase interaction site; other site
1157951010676	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1157951010677	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951010678	ABC-ATPase subunit  interface; other site
1157951010679	dimer interface [polypeptide binding]; other site
1157951010680	putative PBP binding regions; other site
1157951010681	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1157951010682	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1157951010683	Walker A/P-loop; other site
1157951010684	ATP binding site [chemical binding]; other site
1157951010685	Q-loop/lid; other site
1157951010686	ABC transporter signature motif; other site
1157951010687	Walker B; other site
1157951010688	D-loop; other site
1157951010689	H-loop/switch region; other site
1157951010690	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1157951010691	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1157951010692	inhibitor-cofactor binding pocket; inhibition site
1157951010693	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951010694	catalytic residue [active]
1157951010695	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1157951010696	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1157951010697	Ligand binding site; other site
1157951010698	Putative Catalytic site; other site
1157951010699	DXD motif; other site
1157951010700	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1157951010701	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
1157951010702	substrate binding site [chemical binding]; other site
1157951010703	cosubstrate binding site; other site
1157951010704	catalytic site [active]
1157951010705	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1157951010706	active site
1157951010707	hexamer interface [polypeptide binding]; other site
1157951010708	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1157951010709	NAD binding site [chemical binding]; other site
1157951010710	substrate binding site [chemical binding]; other site
1157951010711	active site
1157951010712	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1157951010713	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1157951010714	putative active site [active]
1157951010715	putative catalytic site [active]
1157951010716	putative Zn binding site [ion binding]; other site
1157951010717	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1157951010718	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1157951010719	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1157951010720	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1157951010721	NlpC/P60 family; Region: NLPC_P60; pfam00877
1157951010722	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1157951010723	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1157951010724	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1157951010725	Sulfatase; Region: Sulfatase; cl17466
1157951010726	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1157951010727	Sulfatase; Region: Sulfatase; cl17466
1157951010728	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1157951010729	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951010730	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
1157951010731	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1157951010732	Walker A/P-loop; other site
1157951010733	ATP binding site [chemical binding]; other site
1157951010734	Q-loop/lid; other site
1157951010735	ABC transporter signature motif; other site
1157951010736	Walker B; other site
1157951010737	D-loop; other site
1157951010738	H-loop/switch region; other site
1157951010739	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1157951010740	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951010741	ABC-ATPase subunit  interface; other site
1157951010742	dimer interface [polypeptide binding]; other site
1157951010743	putative PBP binding regions; other site
1157951010744	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
1157951010745	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1157951010746	putative hemin binding site; other site
1157951010747	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
1157951010748	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1157951010749	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1157951010750	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1157951010751	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951010752	N-terminal plug; other site
1157951010753	ligand-binding site [chemical binding]; other site
1157951010754	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1157951010755	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1157951010756	N-terminal plug; other site
1157951010757	Hemin uptake protein hemP; Region: hemP; pfam10636
1157951010758	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1157951010759	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1157951010760	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1157951010761	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1157951010762	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1157951010763	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1157951010764	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1157951010765	putative inner membrane protein; Provisional; Region: PRK10983
1157951010766	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1157951010767	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1157951010768	FAD binding domain; Region: FAD_binding_4; pfam01565
1157951010769	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1157951010770	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1157951010771	CoenzymeA binding site [chemical binding]; other site
1157951010772	subunit interaction site [polypeptide binding]; other site
1157951010773	PHB binding site; other site
1157951010774	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1157951010775	putative ABC transporter; Region: ycf24; CHL00085
1157951010776	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1157951010777	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1157951010778	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1157951010779	Walker A/P-loop; other site
1157951010780	ATP binding site [chemical binding]; other site
1157951010781	Q-loop/lid; other site
1157951010782	ABC transporter signature motif; other site
1157951010783	Walker B; other site
1157951010784	D-loop; other site
1157951010785	H-loop/switch region; other site
1157951010786	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1157951010787	FeS assembly protein SufD; Region: sufD; TIGR01981
1157951010788	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1157951010789	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1157951010790	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951010791	catalytic residue [active]
1157951010792	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1157951010793	L,D-transpeptidase; Provisional; Region: PRK10190
1157951010794	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1157951010795	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1157951010796	Murein lipoprotein [Cell envelope biogenesis, outer membrane]; Region: COG4238; cl11539
1157951010797	pyruvate kinase; Provisional; Region: PRK09206
1157951010798	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1157951010799	domain interfaces; other site
1157951010800	active site
1157951010801	multidrug efflux protein; Reviewed; Region: PRK01766
1157951010802	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1157951010803	cation binding site [ion binding]; other site
1157951010804	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1157951010805	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1157951010806	Lumazine binding domain; Region: Lum_binding; pfam00677
1157951010807	Lumazine binding domain; Region: Lum_binding; pfam00677
1157951010808	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1157951010809	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1157951010810	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951010811	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951010812	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1157951010813	Carbohydrate phosphorylase; Region: Phosphorylase; pfam00343
1157951010814	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1157951010815	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951010816	S-adenosylmethionine binding site [chemical binding]; other site
1157951010817	putative transporter; Provisional; Region: PRK11043
1157951010818	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951010819	putative substrate translocation pore; other site
1157951010820	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1157951010821	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951010822	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951010823	dimerization interface [polypeptide binding]; other site
1157951010824	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1157951010825	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1157951010826	DNA binding site [nucleotide binding]
1157951010827	domain linker motif; other site
1157951010828	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1157951010829	dimerization interface [polypeptide binding]; other site
1157951010830	ligand binding site [chemical binding]; other site
1157951010831	superoxide dismutase; Provisional; Region: PRK10543
1157951010832	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1157951010833	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1157951010834	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1157951010835	putative GSH binding site [chemical binding]; other site
1157951010836	catalytic residues [active]
1157951010837	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1157951010838	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1157951010839	dimer interface [polypeptide binding]; other site
1157951010840	catalytic site [active]
1157951010841	putative active site [active]
1157951010842	putative substrate binding site [chemical binding]; other site
1157951010843	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1157951010844	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1157951010845	dimer interface [polypeptide binding]; other site
1157951010846	active site
1157951010847	metal binding site [ion binding]; metal-binding site
1157951010848	glutathione binding site [chemical binding]; other site
1157951010849	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1157951010850	MarR family; Region: MarR_2; cl17246
1157951010851	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1157951010852	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1157951010853	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1157951010854	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1157951010855	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1157951010856	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1157951010857	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1157951010858	active site
1157951010859	HIGH motif; other site
1157951010860	dimer interface [polypeptide binding]; other site
1157951010861	KMSKS motif; other site
1157951010862	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1157951010863	RNA binding surface [nucleotide binding]; other site
1157951010864	pyridoxamine kinase; Validated; Region: PRK05756
1157951010865	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1157951010866	dimer interface [polypeptide binding]; other site
1157951010867	pyridoxal binding site [chemical binding]; other site
1157951010868	ATP binding site [chemical binding]; other site
1157951010869	glutathionine S-transferase; Provisional; Region: PRK10542
1157951010870	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1157951010871	C-terminal domain interface [polypeptide binding]; other site
1157951010872	GSH binding site (G-site) [chemical binding]; other site
1157951010873	dimer interface [polypeptide binding]; other site
1157951010874	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1157951010875	dimer interface [polypeptide binding]; other site
1157951010876	N-terminal domain interface [polypeptide binding]; other site
1157951010877	substrate binding pocket (H-site) [chemical binding]; other site
1157951010878	Uncharacterized integral membrane protein [Function unknown]; Region: COG3739
1157951010879	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1157951010880	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1157951010881	NAD binding site [chemical binding]; other site
1157951010882	homotetramer interface [polypeptide binding]; other site
1157951010883	homodimer interface [polypeptide binding]; other site
1157951010884	substrate binding site [chemical binding]; other site
1157951010885	active site
1157951010886	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1157951010887	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1157951010888	Walker A/P-loop; other site
1157951010889	ATP binding site [chemical binding]; other site
1157951010890	Q-loop/lid; other site
1157951010891	ABC transporter signature motif; other site
1157951010892	Walker B; other site
1157951010893	D-loop; other site
1157951010894	H-loop/switch region; other site
1157951010895	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1157951010896	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1157951010897	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1157951010898	Walker A/P-loop; other site
1157951010899	ATP binding site [chemical binding]; other site
1157951010900	Q-loop/lid; other site
1157951010901	ABC transporter signature motif; other site
1157951010902	Walker B; other site
1157951010903	D-loop; other site
1157951010904	H-loop/switch region; other site
1157951010905	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1157951010906	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1157951010907	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1157951010908	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951010909	dimer interface [polypeptide binding]; other site
1157951010910	conserved gate region; other site
1157951010911	putative PBP binding loops; other site
1157951010912	ABC-ATPase subunit interface; other site
1157951010913	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1157951010914	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1157951010915	dimer interface [polypeptide binding]; other site
1157951010916	conserved gate region; other site
1157951010917	putative PBP binding loops; other site
1157951010918	ABC-ATPase subunit interface; other site
1157951010919	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1157951010920	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1157951010921	peptide binding site [polypeptide binding]; other site
1157951010922	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1157951010923	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951010924	Walker A motif; other site
1157951010925	ATP binding site [chemical binding]; other site
1157951010926	Walker B motif; other site
1157951010927	arginine finger; other site
1157951010928	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1157951010929	phage shock protein PspA; Provisional; Region: PRK10698
1157951010930	phage shock protein B; Provisional; Region: pspB; PRK09458
1157951010931	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1157951010932	phage shock protein C; Region: phageshock_pspC; TIGR02978
1157951010933	Predicted ATPase [General function prediction only]; Region: COG3106
1157951010934	hypothetical protein; Provisional; Region: PRK05415
1157951010935	Domain of unknown function (DUF697); Region: DUF697; cl12064
1157951010936	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1157951010937	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1157951010938	putative aromatic amino acid binding site; other site
1157951010939	PAS domain; Region: PAS; smart00091
1157951010940	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951010941	Walker A motif; other site
1157951010942	ATP binding site [chemical binding]; other site
1157951010943	Walker B motif; other site
1157951010944	arginine finger; other site
1157951010945	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1157951010946	dimer interface [polypeptide binding]; other site
1157951010947	catalytic triad [active]
1157951010948	peroxidatic and resolving cysteines [active]
1157951010949	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1157951010950	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1157951010951	peptide binding site [polypeptide binding]; other site
1157951010952	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1157951010953	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1157951010954	Cl binding site [ion binding]; other site
1157951010955	oligomer interface [polypeptide binding]; other site
1157951010956	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1157951010957	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1157951010958	Ligand Binding Site [chemical binding]; other site
1157951010959	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951010960	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951010961	non-specific DNA binding site [nucleotide binding]; other site
1157951010962	salt bridge; other site
1157951010963	sequence-specific DNA binding site [nucleotide binding]; other site
1157951010964	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
1157951010965	aspartate racemase; Region: asp_race; TIGR00035
1157951010966	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1157951010967	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1157951010968	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1157951010969	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1157951010970	putative N-terminal domain interface [polypeptide binding]; other site
1157951010971	putative dimer interface [polypeptide binding]; other site
1157951010972	putative substrate binding pocket (H-site) [chemical binding]; other site
1157951010973	Peptidase M66; Region: Peptidase_M66; pfam10462
1157951010974	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1157951010975	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1157951010976	ligand binding site [chemical binding]; other site
1157951010977	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1157951010978	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1157951010979	Walker A/P-loop; other site
1157951010980	ATP binding site [chemical binding]; other site
1157951010981	Q-loop/lid; other site
1157951010982	ABC transporter signature motif; other site
1157951010983	Walker B; other site
1157951010984	D-loop; other site
1157951010985	H-loop/switch region; other site
1157951010986	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1157951010987	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1157951010988	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1157951010989	TM-ABC transporter signature motif; other site
1157951010990	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1157951010991	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1157951010992	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1157951010993	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1157951010994	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1157951010995	Ligand Binding Site [chemical binding]; other site
1157951010996	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1157951010997	Ligand Binding Site [chemical binding]; other site
1157951010998	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1157951010999	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1157951011000	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951011001	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1157951011002	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1157951011003	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
1157951011004	DNA-specific endonuclease I; Provisional; Region: PRK15137
1157951011005	Endonuclease I; Region: Endonuclease_1; pfam04231
1157951011006	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1157951011007	hypothetical protein; Provisional; Region: PRK10536
1157951011008	YodA lipocalin-like domain; Region: YodA; cl01365
1157951011009	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1157951011010	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1157951011011	FAD binding pocket [chemical binding]; other site
1157951011012	FAD binding motif [chemical binding]; other site
1157951011013	phosphate binding motif [ion binding]; other site
1157951011014	NAD binding pocket [chemical binding]; other site
1157951011015	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1157951011016	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1157951011017	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1157951011018	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1157951011019	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1157951011020	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951011021	DNA-binding site [nucleotide binding]; DNA binding site
1157951011022	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951011023	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951011024	homodimer interface [polypeptide binding]; other site
1157951011025	catalytic residue [active]
1157951011026	HutD; Region: HutD; cl01532
1157951011027	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1157951011028	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1157951011029	virion protein; Provisional; Region: V; PHA02564
1157951011030	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1157951011031	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1157951011032	ATP binding site [chemical binding]; other site
1157951011033	Mg++ binding site [ion binding]; other site
1157951011034	motif III; other site
1157951011035	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951011036	nucleotide binding region [chemical binding]; other site
1157951011037	ATP-binding site [chemical binding]; other site
1157951011038	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1157951011039	putative RNA binding site [nucleotide binding]; other site
1157951011040	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
1157951011041	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1157951011042	dimer interface [polypeptide binding]; other site
1157951011043	PYR/PP interface [polypeptide binding]; other site
1157951011044	TPP binding site [chemical binding]; other site
1157951011045	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1157951011046	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1157951011047	TPP-binding site [chemical binding]; other site
1157951011048	dimer interface [polypeptide binding]; other site
1157951011049	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951011050	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951011051	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951011052	dimerization interface [polypeptide binding]; other site
1157951011053	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1157951011054	Integrase core domain; Region: rve; pfam00665
1157951011055	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1157951011056	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
1157951011057	DDE domain; Region: DDE_Tnp_IS240; pfam13610
1157951011058	Fic/DOC family; Region: Fic; pfam02661
1157951011059	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1157951011060	DNA binding site [nucleotide binding]
1157951011061	Int/Topo IB signature motif; other site
1157951011062	active site
1157951011063	GTP-binding protein YchF; Reviewed; Region: PRK09601
1157951011064	YchF GTPase; Region: YchF; cd01900
1157951011065	G1 box; other site
1157951011066	GTP/Mg2+ binding site [chemical binding]; other site
1157951011067	Switch I region; other site
1157951011068	G2 box; other site
1157951011069	Switch II region; other site
1157951011070	G3 box; other site
1157951011071	G4 box; other site
1157951011072	G5 box; other site
1157951011073	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1157951011074	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1157951011075	putative active site [active]
1157951011076	catalytic residue [active]
1157951011077	hypothetical protein; Provisional; Region: PRK10692
1157951011078	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1157951011079	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1157951011080	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1157951011081	active site
1157951011082	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1157951011083	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1157951011084	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
1157951011085	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1157951011086	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1157951011087	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1157951011088	tRNA; other site
1157951011089	putative tRNA binding site [nucleotide binding]; other site
1157951011090	putative NADP binding site [chemical binding]; other site
1157951011091	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1157951011092	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1157951011093	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1157951011094	RF-1 domain; Region: RF-1; pfam00472
1157951011095	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1157951011096	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951011097	hypothetical protein; Provisional; Region: PRK10941
1157951011098	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1157951011099	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1157951011100	TPR motif; other site
1157951011101	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1157951011102	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1157951011103	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
1157951011104	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951011105	FeS/SAM binding site; other site
1157951011106	putative transporter; Provisional; Region: PRK11660
1157951011107	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1157951011108	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1157951011109	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1157951011110	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
1157951011111	active site
1157951011112	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
1157951011113	active site
1157951011114	catalytic residues [active]
1157951011115	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1157951011116	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1157951011117	Putative methyltransferase; Region: Methyltransf_20; pfam12147
1157951011118	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1157951011119	PAS fold; Region: PAS_4; pfam08448
1157951011120	Cache domain; Region: Cache_1; pfam02743
1157951011121	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951011122	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1157951011123	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951011124	hydroxyproline-2-epimerase; Provisional; Region: PRK13970
1157951011125	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
1157951011126	FAD dependent oxidoreductase; Region: DAO; pfam01266
1157951011127	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1157951011128	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1157951011129	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1157951011130	inhibitor site; inhibition site
1157951011131	active site
1157951011132	dimer interface [polypeptide binding]; other site
1157951011133	catalytic residue [active]
1157951011134	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1157951011135	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
1157951011136	NAD(P) binding site [chemical binding]; other site
1157951011137	catalytic residues [active]
1157951011138	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1157951011139	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1157951011140	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1157951011141	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1157951011142	putative ligand binding site [chemical binding]; other site
1157951011143	NAD binding site [chemical binding]; other site
1157951011144	dimerization interface [polypeptide binding]; other site
1157951011145	catalytic site [active]
1157951011146	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1157951011147	lipoprotein; Provisional; Region: PRK10598
1157951011148	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1157951011149	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951011150	putative substrate translocation pore; other site
1157951011151	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1157951011152	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1157951011153	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1157951011154	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1157951011155	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1157951011156	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1157951011157	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1157951011158	active site
1157951011159	HIGH motif; other site
1157951011160	KMSK motif region; other site
1157951011161	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1157951011162	tRNA binding surface [nucleotide binding]; other site
1157951011163	anticodon binding site; other site
1157951011164	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1157951011165	putative metal binding site [ion binding]; other site
1157951011166	copper homeostasis protein CutC; Provisional; Region: PRK11572
1157951011167	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1157951011168	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951011169	S-adenosylmethionine binding site [chemical binding]; other site
1157951011170	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951011171	S-adenosylmethionine binding site [chemical binding]; other site
1157951011172	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1157951011173	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690
1157951011174	nudix motif; other site
1157951011175	Domain of unknown function (DUF4377); Region: DUF4377; pfam14302
1157951011176	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1157951011177	dimer interface [polypeptide binding]; other site
1157951011178	anticodon binding site; other site
1157951011179	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1157951011180	tRNA synthetases class II (D, K and N); Region: tRNA-synt_2; pfam00152
1157951011181	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1157951011182	homodimer interface [polypeptide binding]; other site
1157951011183	motif 1; other site
1157951011184	active site
1157951011185	motif 2; other site
1157951011186	GAD domain; Region: GAD; pfam02938
1157951011187	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1157951011188	active site
1157951011189	motif 3; other site
1157951011190	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1157951011191	nudix motif; other site
1157951011192	hypothetical protein; Validated; Region: PRK00110
1157951011193	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1157951011194	active site
1157951011195	putative DNA-binding cleft [nucleotide binding]; other site
1157951011196	dimer interface [polypeptide binding]; other site
1157951011197	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1157951011198	RuvA N terminal domain; Region: RuvA_N; pfam01330
1157951011199	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1157951011200	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1157951011201	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1157951011202	Walker A motif; other site
1157951011203	ATP binding site [chemical binding]; other site
1157951011204	Walker B motif; other site
1157951011205	arginine finger; other site
1157951011206	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1157951011207	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1157951011208	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1157951011209	ABC-ATPase subunit  interface; other site
1157951011210	dimer interface [polypeptide binding]; other site
1157951011211	putative PBP binding regions; other site
1157951011212	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1157951011213	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1157951011214	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1157951011215	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1157951011216	metal binding site [ion binding]; metal-binding site
1157951011217	putative peptidase; Provisional; Region: PRK11649
1157951011218	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1157951011219	Peptidase family M23; Region: Peptidase_M23; pfam01551
1157951011220	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1157951011221	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1157951011222	putative acyl-acceptor binding pocket; other site
1157951011223	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951011224	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951011225	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951011226	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951011227	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951011228	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951011229	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951011230	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951011231	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951011232	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951011233	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951011234	pyruvate kinase; Provisional; Region: PRK05826
1157951011235	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1157951011236	domain interfaces; other site
1157951011237	active site
1157951011238	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1157951011239	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1157951011240	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1157951011241	putative active site [active]
1157951011242	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1157951011243	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1157951011244	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1157951011245	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1157951011246	dimer interface [polypeptide binding]; other site
1157951011247	pyridoxal binding site [chemical binding]; other site
1157951011248	ATP binding site [chemical binding]; other site
1157951011249	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1157951011250	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1157951011251	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1157951011252	homotrimer interaction site [polypeptide binding]; other site
1157951011253	putative active site [active]
1157951011254	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1157951011255	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1157951011256	DEAD_2; Region: DEAD_2; pfam06733
1157951011257	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1157951011258	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1157951011259	Glycoprotease family; Region: Peptidase_M22; pfam00814
1157951011260	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
1157951011261	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1157951011262	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1157951011263	acyl-activating enzyme (AAE) consensus motif; other site
1157951011264	putative AMP binding site [chemical binding]; other site
1157951011265	putative active site [active]
1157951011266	putative CoA binding site [chemical binding]; other site
1157951011267	ribonuclease D; Provisional; Region: PRK10829
1157951011268	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1157951011269	catalytic site [active]
1157951011270	putative active site [active]
1157951011271	putative substrate binding site [chemical binding]; other site
1157951011272	HRDC domain; Region: HRDC; pfam00570
1157951011273	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1157951011274	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1157951011275	Switch I; other site
1157951011276	Switch II; other site
1157951011277	cell division inhibitor MinD; Provisional; Region: PRK10818
1157951011278	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1157951011279	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1157951011280	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1157951011281	YcgL domain; Region: YcgL; pfam05166
1157951011282	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1157951011283	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
1157951011284	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1157951011285	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1157951011286	hypothetical protein; Provisional; Region: PRK10691
1157951011287	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1157951011288	hypothetical protein; Provisional; Region: PRK05170
1157951011289	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1157951011290	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1157951011291	active site
1157951011292	catalytic tetrad [active]
1157951011293	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1157951011294	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951011295	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951011296	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951011297	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951011298	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951011299	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951011300	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951011301	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951011302	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951011303	Fimbrial protein; Region: Fimbrial; cl01416
1157951011304	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1157951011305	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1157951011306	non-specific DNA binding site [nucleotide binding]; other site
1157951011307	salt bridge; other site
1157951011308	sequence-specific DNA binding site [nucleotide binding]; other site
1157951011309	glutaredoxin 2; Provisional; Region: PRK10387
1157951011310	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1157951011311	C-terminal domain interface [polypeptide binding]; other site
1157951011312	GSH binding site (G-site) [chemical binding]; other site
1157951011313	catalytic residues [active]
1157951011314	putative dimer interface [polypeptide binding]; other site
1157951011315	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1157951011316	N-terminal domain interface [polypeptide binding]; other site
1157951011317	META domain; Region: META; cl01245
1157951011318	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1157951011319	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1157951011320	putative ligand binding site [chemical binding]; other site
1157951011321	putative NAD binding site [chemical binding]; other site
1157951011322	catalytic site [active]
1157951011323	hypothetical protein; Provisional; Region: PRK10695
1157951011324	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1157951011325	Protein of unknown function (DUF1318); Region: DUF1318; pfam07027
1157951011326	azoreductase; Reviewed; Region: PRK00170
1157951011327	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1157951011328	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1157951011329	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1157951011330	ATP binding site [chemical binding]; other site
1157951011331	putative Mg++ binding site [ion binding]; other site
1157951011332	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1157951011333	nucleotide binding region [chemical binding]; other site
1157951011334	ATP-binding site [chemical binding]; other site
1157951011335	Helicase associated domain (HA2); Region: HA2; pfam04408
1157951011336	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1157951011337	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1157951011338	putative major fimbrial protein SthE; Provisional; Region: PRK15292
1157951011339	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951011340	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951011341	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951011342	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951011343	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951011344	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951011345	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951011346	PapC C-terminal domain; Region: PapC_C; pfam13953
1157951011347	Fimbrial protein; Region: Fimbrial; cl01416
1157951011348	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1157951011349	Spore germination protein; Region: Spore_permease; cl17796
1157951011350	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1157951011351	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1157951011352	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1157951011353	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1157951011354	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1157951011355	ligand binding site [chemical binding]; other site
1157951011356	homodimer interface [polypeptide binding]; other site
1157951011357	NAD(P) binding site [chemical binding]; other site
1157951011358	trimer interface B [polypeptide binding]; other site
1157951011359	trimer interface A [polypeptide binding]; other site
1157951011360	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1157951011361	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1157951011362	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1157951011363	universal stress protein UspE; Provisional; Region: PRK11175
1157951011364	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1157951011365	Ligand Binding Site [chemical binding]; other site
1157951011366	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1157951011367	Ligand Binding Site [chemical binding]; other site
1157951011368	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1157951011369	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1157951011370	ligand binding site [chemical binding]; other site
1157951011371	flexible hinge region; other site
1157951011372	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1157951011373	putative switch regulator; other site
1157951011374	non-specific DNA interactions [nucleotide binding]; other site
1157951011375	DNA binding site [nucleotide binding]
1157951011376	sequence specific DNA binding site [nucleotide binding]; other site
1157951011377	putative cAMP binding site [chemical binding]; other site
1157951011378	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
1157951011379	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
1157951011380	NAD(P) binding site [chemical binding]; other site
1157951011381	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1157951011382	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951011383	catalytic residue [active]
1157951011384	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1157951011385	aromatic amino acid transport protein; Region: araaP; TIGR00837
1157951011386	Predicted transcriptional regulators [Transcription]; Region: COG1695
1157951011387	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1157951011388	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1157951011389	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951011390	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1157951011391	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951011392	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1157951011393	Coenzyme A binding pocket [chemical binding]; other site
1157951011394	HlyD family secretion protein; Region: HlyD; pfam00529
1157951011395	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1157951011396	HlyD family secretion protein; Region: HlyD_3; pfam13437
1157951011397	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1157951011398	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1157951011399	Walker A/P-loop; other site
1157951011400	ATP binding site [chemical binding]; other site
1157951011401	Q-loop/lid; other site
1157951011402	ABC transporter signature motif; other site
1157951011403	Walker B; other site
1157951011404	D-loop; other site
1157951011405	H-loop/switch region; other site
1157951011406	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1157951011407	Walker A/P-loop; other site
1157951011408	ATP binding site [chemical binding]; other site
1157951011409	Q-loop/lid; other site
1157951011410	ABC transporter signature motif; other site
1157951011411	Walker B; other site
1157951011412	D-loop; other site
1157951011413	H-loop/switch region; other site
1157951011414	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1157951011415	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1157951011416	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1157951011417	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1157951011418	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1157951011419	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1157951011420	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1157951011421	dimer interface [polypeptide binding]; other site
1157951011422	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1157951011423	catalytic triad [active]
1157951011424	peroxidatic and resolving cysteines [active]
1157951011425	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1157951011426	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1157951011427	catalytic residue [active]
1157951011428	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1157951011429	catalytic residues [active]
1157951011430	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1157951011431	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1157951011432	Uncharacterized conserved protein [Function unknown]; Region: COG4933
1157951011433	AAA domain; Region: AAA_17; pfam13207
1157951011434	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1157951011435	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1157951011436	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951011437	DNA-binding site [nucleotide binding]; DNA binding site
1157951011438	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1157951011439	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951011440	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951011441	homodimer interface [polypeptide binding]; other site
1157951011442	catalytic residue [active]
1157951011443	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951011444	Coenzyme A binding pocket [chemical binding]; other site
1157951011445	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
1157951011446	Predicted permeases [General function prediction only]; Region: COG0679
1157951011447	AMP nucleosidase; Provisional; Region: PRK08292
1157951011448	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1157951011449	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1157951011450	Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg6; cd04781
1157951011451	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
1157951011452	DNA binding residues [nucleotide binding]
1157951011453	putative dimer interface [polypeptide binding]; other site
1157951011454	putative metal binding residues [ion binding]; other site
1157951011455	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1157951011456	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1157951011457	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1157951011458	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1157951011459	Zn2+ binding site [ion binding]; other site
1157951011460	Mg2+ binding site [ion binding]; other site
1157951011461	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951011462	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951011463	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1157951011464	putative effector binding pocket; other site
1157951011465	dimerization interface [polypeptide binding]; other site
1157951011466	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1157951011467	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1157951011468	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1157951011469	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
1157951011470	AzlC protein; Region: AzlC; cl00570
1157951011471	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1157951011472	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1157951011473	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951011474	leucine export protein LeuE; Provisional; Region: PRK10958
1157951011475	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1157951011476	active site
1157951011477	catalytic motif [active]
1157951011478	Zn binding site [ion binding]; other site
1157951011479	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a...; Region: Nudix_Hydrolase_1; cd03674
1157951011480	nudix motif; other site
1157951011481	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1157951011482	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1157951011483	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951011484	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951011485	dimerization interface [polypeptide binding]; other site
1157951011486	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1157951011487	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1157951011488	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1157951011489	topology modulation protein; Reviewed; Region: PRK08118
1157951011490	AAA domain; Region: AAA_17; pfam13207
1157951011491	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1157951011492	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951011493	Coenzyme A binding pocket [chemical binding]; other site
1157951011494	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1157951011495	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
1157951011496	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951011497	Coenzyme A binding pocket [chemical binding]; other site
1157951011498	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1157951011499	putative homodimer interface [polypeptide binding]; other site
1157951011500	putative homotetramer interface [polypeptide binding]; other site
1157951011501	putative metal binding site [ion binding]; other site
1157951011502	putative homodimer-homodimer interface [polypeptide binding]; other site
1157951011503	putative allosteric switch controlling residues; other site
1157951011504	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1157951011505	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1157951011506	substrate binding site [chemical binding]; other site
1157951011507	catalytic Zn binding site [ion binding]; other site
1157951011508	NAD binding site [chemical binding]; other site
1157951011509	structural Zn binding site [ion binding]; other site
1157951011510	dimer interface [polypeptide binding]; other site
1157951011511	S-formylglutathione hydrolase; Region: PLN02442
1157951011512	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1157951011513	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1157951011514	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1157951011515	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1157951011516	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1157951011517	Coenzyme A binding pocket [chemical binding]; other site
1157951011518	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1157951011519	D-cysteine desulfhydrase; Validated; Region: PRK03910
1157951011520	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1157951011521	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951011522	catalytic residue [active]
1157951011523	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1157951011524	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1157951011525	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1157951011526	Helix-turn-helix domain; Region: HTH_18; pfam12833
1157951011527	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951011528	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1157951011529	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1157951011530	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1157951011531	dimerization interface [polypeptide binding]; other site
1157951011532	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1157951011533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951011534	putative substrate translocation pore; other site
1157951011535	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1157951011536	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1157951011537	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951011538	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1157951011539	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1157951011540	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1157951011541	DNA binding site [nucleotide binding]
1157951011542	active site
1157951011543	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
1157951011544	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
1157951011545	homotetramer interface [polypeptide binding]; other site
1157951011546	ligand binding site [chemical binding]; other site
1157951011547	catalytic site [active]
1157951011548	NAD binding site [chemical binding]; other site
1157951011549	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1157951011550	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1157951011551	Nucleoside recognition; Region: Gate; pfam07670
1157951011552	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1157951011553	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1157951011554	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1157951011555	ligand binding site [chemical binding]; other site
1157951011556	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1157951011557	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1157951011558	DNA-binding site [nucleotide binding]; DNA binding site
1157951011559	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1157951011560	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1157951011561	homodimer interface [polypeptide binding]; other site
1157951011562	catalytic residue [active]
1157951011563	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1157951011564	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951011565	putative substrate translocation pore; other site
1157951011566	putative transporter; Provisional; Region: PRK10054
1157951011567	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951011568	putative substrate translocation pore; other site
1157951011569	Helix-turn-helix domain; Region: HTH_31; pfam13560
1157951011570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951011571	putative substrate translocation pore; other site
1157951011572	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1157951011573	putative S-transferase; Provisional; Region: PRK11752
1157951011574	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1157951011575	C-terminal domain interface [polypeptide binding]; other site
1157951011576	GSH binding site (G-site) [chemical binding]; other site
1157951011577	dimer interface [polypeptide binding]; other site
1157951011578	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1157951011579	dimer interface [polypeptide binding]; other site
1157951011580	N-terminal domain interface [polypeptide binding]; other site
1157951011581	active site
1157951011582	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1157951011583	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1157951011584	dimer interface [polypeptide binding]; other site
1157951011585	active site
1157951011586	metal binding site [ion binding]; metal-binding site
1157951011587	Anthrax toxin LF subunit; Region: Anthrax_toxA; pfam03497
1157951011588	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1157951011589	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1157951011590	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1157951011591	active site
1157951011592	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951011593	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1157951011594	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1157951011595	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1157951011596	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1157951011597	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1157951011598	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1157951011599	MarR family; Region: MarR_2; cl17246
1157951011600	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1157951011601	EamA-like transporter family; Region: EamA; pfam00892
1157951011602	EamA-like transporter family; Region: EamA; pfam00892
1157951011603	Glycosyl hydrolases related to GH101 family; Region: GHL; pfam11308
1157951011604	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1157951011605	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1157951011606	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1157951011607	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1157951011608	catalytic residue [active]
1157951011609	Domain of unknown function (DUF4184); Region: DUF4184; pfam13803
1157951011610	hypothetical protein; Validated; Region: PRK00124
1157951011611	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1157951011612	S-adenosylmethionine binding site [chemical binding]; other site
1157951011613	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
1157951011614	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1157951011615	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1157951011616	active site
1157951011617	His-Xaa-Ser system protein HsxD; Region: chp_LLNDYxLRE; TIGR03976
1157951011618	His-Xaa-Ser system radical SAM maturase HxsB; Region: rSAM_paired_1; TIGR03978
1157951011619	His-Xaa-Ser system radical SAM maturase HxsC; Region: rSAM_pair_HxsC; TIGR03977
1157951011620	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1157951011621	FeS/SAM binding site; other site
1157951011622	His-Xaa-Ser repeat protein HxsA; Region: His_Ser_Rich; TIGR03979
1157951011623	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1157951011624	Protein of unknown function, DUF481; Region: DUF481; pfam04338
1157951011625	YjbD family (DUF3811); Region: DUF3811; cl08125
1157951011626	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1157951011627	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
1157951011628	active site residue [active]
1157951011629	AAA domain; Region: AAA_17; cl17253
1157951011630	aminoglycoside resistance protein; Provisional; Region: PRK13746
1157951011631	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1157951011632	active site
1157951011633	NTP binding site [chemical binding]; other site
1157951011634	metal binding triad [ion binding]; metal-binding site
1157951011635	antibiotic binding site [chemical binding]; other site
1157951011636	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1157951011637	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1157951011638	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1157951011639	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1157951011640	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1157951011641	FMN binding site [chemical binding]; other site
1157951011642	active site
1157951011643	substrate binding site [chemical binding]; other site
1157951011644	catalytic residue [active]
1157951011645	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1157951011646	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951011647	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951011648	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951011649	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951011650	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1157951011651	Fimbrial protein; Region: Fimbrial; pfam00419
1157951011652	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1157951011653	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951011654	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951011655	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1157951011656	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1157951011657	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1157951011658	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1157951011659	PapC N-terminal domain; Region: PapC_N; pfam13954
1157951011660	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1157951011661	PapC C-terminal domain; Region: PapC_C; pfam13953