-- dump date 20140620_005737 -- class Genbank::CDS -- table cds_note -- id note YP_001185508.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001185509.1 binds the polymerase to DNA and acts as a sliding clamp YP_001185510.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001185511.1 negatively supercoils closed circular double-stranded DNA YP_001185512.1 PFAM: phosphatidate cytidylyltransferase YP_001185513.1 PFAM: phospholipid/glycerol acyltransferase YP_001185515.1 PFAM: phosphoesterase, PA-phosphatase related; Dual specificity protein phosphatase YP_001185516.1 PFAM: alpha/beta hydrolase fold YP_001185517.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001185518.1 PFAM: phospholipid/glycerol acyltransferase YP_001185519.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001185520.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001185521.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001185522.1 TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001185523.2 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001185524.1 PFAM: type IV pilus assembly PilZ YP_001185525.1 PFAM: NLP/P60 protein YP_001185526.1 PFAM: Tir chaperone family protein YP_001185530.1 TIGRFAM: type III secretion outer membrane pore, YscC/HrcC family; PFAM: type II and III secretion system protein; NolW domain protein YP_001185533.1 TIGRFAM: type III secretion apparatus protein, HrpE/YscL family; PFAM: HrpE family protein YP_001185535.1 TIGRFAM: type III secretion apparatus lipoprotein, YscJ/HrcJ family; PFAM: secretory protein YscJ/FliF family protein YP_001185536.1 TIGRFAM: type III secretion apparatus protein, YscI/HrpB family YP_001185537.1 PFAM: HrpZ family protein YP_001185539.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001185540.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001185542.1 PFAM: transposase IS66 YP_001185543.1 PFAM: IS66 Orf2 family protein YP_001185544.1 TIGRFAM: type III secretion effector delivery regulator, TyeA family; type III secretion regulator YopN/LcrE/InvE/MxiC YP_001185545.1 TIGRFAM: type III secretion protein, HrcV family; PFAM: type III secretion FHIPEP protein YP_001185546.1 TIGRFAM: type III secretion apparatus protein, YscD/HrpQ family YP_001185547.1 TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase YP_001185551.1 PFAM: surface presentation of antigens (SPOA) protein YP_001185552.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_001185553.1 TIGRFAM: type III secretion protein, HrpO family; PFAM: export protein FliQ, family 3 YP_001185554.1 TIGRFAM: type III secretion protein SpaR/YscT/HrcT; PFAM: type III secretion system inner membrane R protein YP_001185555.1 TIGRFAM: type III secretion protein, YscU/HrpY family; PFAM: type III secretion exporter YP_001185556.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165 YP_001185557.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001185558.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001185559.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44 YP_001185560.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001185561.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001185562.1 PFAM: Peptidoglycan-binding LysM YP_001185563.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein YP_001185564.1 PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001185565.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001185566.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001185567.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001185568.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter YP_001185569.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001185570.1 PFAM: sulfatase YP_001185571.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001185572.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001185573.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001185574.1 PFAM: aldo/keto reductase YP_001185575.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001185576.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001185577.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001185579.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001185581.1 PFAM: protein of unknown function DUF1458 YP_001185582.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001185584.1 PFAM: nucleoside recognition domain protein YP_001185586.1 PFAM: protein of unknown function DUF1328 YP_001185588.1 PFAM: thioesterase superfamily protein YP_001185589.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001185590.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; Cache, type 2 domain protein YP_001185591.1 PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001185592.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component YP_001185593.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit YP_001185594.1 PFAM: Aldose 1-epimerase YP_001185595.1 PFAM: ImpA domain protein YP_001185596.1 PFAM: uncharacterised conserved protein UCP028301 YP_001185597.1 PFAM: protein of unknown function DUF877 YP_001185598.1 PFAM: GPW/gp25 family protein YP_001185601.1 PFAM: protein of unknown function DUF879 YP_001185602.1 PFAM: protein of unknown function DUF1305 YP_001185603.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001185604.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001185606.1 PFAM: Forkhead-associated protein YP_001185608.1 PFAM: protein of unknown function DUF876 YP_001185610.1 PFAM: ImcF domain protein; protein of unknown function DUF1215 YP_001185611.1 PFAM: protein phosphatase 2C domain protein; Stage II sporulation E family protein YP_001185612.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001185613.1 PFAM: Rhs element Vgr protein YP_001185614.1 PFAM: glycoside hydrolase, family 19 YP_001185618.1 PFAM: protein of unknown function DUF1311 YP_001185622.1 PFAM: Transglycosylase-associated protein YP_001185624.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001185625.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001185626.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001185628.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001185629.1 PFAM: histone deacetylase superfamily YP_001185630.1 PFAM: extracellular solute-binding protein, family 1 YP_001185631.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001185633.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001185634.1 catalyzes the formation of fumarate from aspartate YP_001185635.1 PFAM: sodium:dicarboxylate symporter YP_001185636.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001185637.1 PFAM: Negative transcriptional regulator YP_001185638.1 PFAM: GCN5-related N-acetyltransferase YP_001185639.1 PFAM: GCN5-related N-acetyltransferase YP_001185640.1 PFAM: helix-turn-helix domain protein YP_001185641.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter YP_001185642.1 PFAM: Asparaginase/glutaminase YP_001185643.1 PFAM: GCN5-related N-acetyltransferase YP_001185644.1 PFAM: Endoribonuclease L-PSP YP_001185645.1 catalyzes the formation of glutamate from glutamine YP_001185646.1 PFAM: Auxin Efflux Carrier YP_001185648.1 PFAM: cytochrome c oxidase, subunit II; cytochrome c, class I; cytochrome C oxidase subunit II, transmembrane region YP_001185649.1 PFAM: cytochrome c oxidase, subunit I YP_001185650.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001185651.1 PFAM: cytochrome c oxidase, subunit III YP_001185655.1 PFAM: cytochrome oxidase assembly YP_001185656.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001185657.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; electron transport protein SCO1/SenC YP_001185658.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_001185660.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001185661.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001185663.1 PFAM: cytochrome c, class I YP_001185664.1 PFAM: DSBA oxidoreductase YP_001185665.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001185666.1 PFAM: transposase IS66 YP_001185667.1 PFAM: IS66 Orf2 family protein YP_001185668.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001185669.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter YP_001185670.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001185671.1 PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase, family 2 YP_001185674.1 PFAM: response regulator receiver YP_001185675.1 PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein YP_001185676.1 PFAM: MCP methyltransferase, CheR-type YP_001185677.1 PFAM: CheB methylesterase YP_001185678.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001185681.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001185682.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001185683.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria YP_001185685.1 TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001185686.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001185687.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component YP_001185688.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001185689.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein YP_001185690.1 PFAM: response regulator receiver YP_001185691.1 PFAM: peptidase M23B YP_001185692.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein YP_001185693.1 PFAM: flagellar protein FliS YP_001185695.1 PFAM: flagellar hook-length control protein YP_001185697.1 TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001185698.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001185699.1 PFAM: OmpA/MotB domain protein YP_001185701.1 PFAM: transcriptional regulator domain protein YP_001185702.1 PFAM: flagellin domain protein YP_001185703.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001185704.1 PFAM: L-lactate permease YP_001185705.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001185706.1 PFAM: protein of unknown function DUF336 YP_001185707.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001185708.1 PFAM: FAD linked oxidase domain protein YP_001185709.1 TIGRFAM: glycolate oxidase, subunit GlcD; PFAM: FAD linked oxidase domain protein YP_001185710.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001185711.1 PFAM: SAF domain YP_001185712.1 TIGRFAM: flagellar basal-body rod protein FlgB YP_001185713.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001185714.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Vibrio parahaemolyticus protein in this cluster is associated with lateral flagella production YP_001185715.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein YP_001185716.1 TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein YP_001185717.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein YP_001185718.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH YP_001185719.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001185720.1 PFAM: Lytic transglycosylase, catalytic YP_001185721.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein YP_001185722.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; in Vibrio parahaemolyticus the protein in this cluster is associated with the lateral flagella YP_001185724.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001185727.1 PFAM: major facilitator superfamily MFS_1 YP_001185728.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001185729.1 PFAM: protein of unknown function DUF1329 YP_001185730.1 PFAM: protein of unknown function DUF1302 YP_001185731.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001185732.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001185733.1 PFAM: aldehyde dehydrogenase YP_001185735.1 PFAM: regulatory protein, LuxR YP_001185737.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_001185738.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001185740.1 PFAM: regulatory protein, TetR YP_001185741.1 PFAM: major facilitator superfamily MFS_1 YP_001185742.1 PFAM: protein of unknown function DUF861, cupin_3 YP_001185743.1 PFAM: aldehyde dehydrogenase YP_001185744.1 PFAM: major facilitator superfamily MFS_1 YP_001185745.1 PFAM: OmpA/MotB domain protein YP_001185746.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001185747.1 PFAM: protein of unknown function DUF1127 YP_001185748.1 PFAM: FAD dependent oxidoreductase YP_001185749.1 PFAM: protein of unknown function UPF0153 YP_001185750.1 PFAM: regulatory protein, AsnC/Lrp family YP_001185751.1 catalyzes the oxidative deamination of D-amino acids YP_001185752.1 PFAM: Endoribonuclease L-PSP YP_001185753.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA YP_001185754.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001185757.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_001185759.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase YP_001185760.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001185761.1 functions as a Na(+)/drug antiporter YP_001185762.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001185763.1 TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001185764.1 PFAM: protein of unknown function DUF526 YP_001185765.1 PFAM: nitrogen regulatory protein P-II YP_001185766.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter YP_001185767.1 PFAM: protein of unknown function UPF0047 YP_001185769.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001185770.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001185771.1 PFAM: protein of unknown function DUF484 YP_001185772.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001185773.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001185774.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001185775.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001185776.1 PFAM: protein of unknown function DUF1289 YP_001185777.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001185778.1 PFAM: lipase, class 3 YP_001185779.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001185783.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001185784.1 PFAM: histidine kinase internal region YP_001185785.1 PFAM: response regulator receiver; LytTr DNA-binding region YP_001185786.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001185787.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane YP_001185788.1 PFAM: protein of unknown function DUF513, hemX YP_001185789.1 PFAM: HemY domain protein YP_001185790.1 PFAM: Disulphide bond formation protein DsbB YP_001185791.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001185792.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001185795.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001185797.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001185798.1 PFAM: cytochrome c, class I; iron permease FTR1 YP_001185800.1 PFAM: protein of unknown function DUF188 YP_001185801.1 PFAM: thioesterase superfamily protein YP_001185802.1 PFAM: ThiJ/PfpI domain protein YP_001185805.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001185806.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001185807.1 PFAM: Ppx/GppA phosphatase YP_001185808.1 PFAM: Ureidoglycolate hydrolase YP_001185809.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001185810.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001185811.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001185812.1 PFAM: extracellular solute-binding protein, family 3 YP_001185813.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; Helix-turn-helix, type 11 domain protein YP_001185814.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001185815.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001185816.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein YP_001185817.1 catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose YP_001185819.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001185820.1 PFAM: flagellar basal body-associated protein FliL YP_001185821.1 PFAM: ABC-2 type transporter YP_001185822.1 PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase YP_001185823.1 PFAM: secretion protein HlyD family protein YP_001185824.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001185825.1 PFAM: protein of unknown function DUF55 YP_001185827.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase YP_001185828.1 PFAM: protein of unknown function DUF710 YP_001185830.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001185831.1 PFAM: peptidase M24; peptidase M24B, X-Pro dipeptidase/aminopeptidase domain protein YP_001185832.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001185833.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol YP_001185835.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001185836.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001185837.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001185838.1 PFAM: regulatory protein, ArsR YP_001185839.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001185840.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001185842.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_001185843.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001185844.1 PFAM: regulatory protein, TetR YP_001185845.1 PFAM: extracellular solute-binding protein, family 1 YP_001185846.1 PFAM: glutamine synthetase, catalytic region YP_001185847.1 PFAM: glutamine synthetase, catalytic region YP_001185848.1 PFAM: aminotransferase class-III YP_001185849.1 PFAM: extracellular solute-binding protein, family 1 YP_001185850.1 PFAM: extracellular solute-binding protein, family 1 YP_001185851.1 PFAM: extracellular solute-binding protein, family 1 YP_001185852.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001185853.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001185854.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001185855.1 PFAM: adenylate cyclase YP_001185856.1 PFAM: protein of unknown function DUF47 YP_001185857.1 PFAM: phosphate transporter YP_001185858.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001185859.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001185861.1 involved in the first step of glutathione biosynthesis YP_001185862.1 PFAM: thioesterase superfamily protein YP_001185863.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold YP_001185864.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001185865.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001185866.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MASE1 domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001185867.1 PFAM: peptidase U61, LD-carboxypeptidase A YP_001185868.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp YP_001185869.1 PFAM: protein of unknown function DUF785 YP_001185870.1 PFAM: RNA-binding S4 domain protein YP_001185871.1 PFAM: phosphoesterase, PA-phosphatase related YP_001185872.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001185873.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001185874.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001185875.1 PFAM: protein of unknown function DUF330 YP_001185876.1 PFAM: Mammalian cell entry related domain protein YP_001185877.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001185878.1 PFAM: protein of unknown function DUF140 YP_001185881.1 PFAM: aldo/keto reductase YP_001185883.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001185884.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001185885.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001185886.1 PFAM: iron-containing alcohol dehydrogenase YP_001185887.1 PFAM: thioesterase superfamily protein YP_001185890.1 PFAM: 17 kDa surface antigen YP_001185891.1 PFAM: regulatory protein, LysR YP_001185892.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001185893.1 PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001185894.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001185896.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase, subunit FdhD YP_001185897.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001185898.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001185899.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase YP_001185900.1 PFAM: beta-ketoacyl synthase YP_001185901.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001185902.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001185903.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001185904.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001185905.1 PFAM: protein of unknown function DUF179 YP_001185906.1 TIGRFAM: TonB family protein YP_001185907.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001185908.1 PFAM: response regulator receiver YP_001185909.1 PFAM: response regulator receiver YP_001185910.1 PFAM: CheW domain protein YP_001185911.1 PFAM: chemotaxis sensory transducer YP_001185912.1 PFAM: MCP methyltransferase, CheR-type YP_001185913.1 PFAM: response regulator receiver; CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Hpt domain protein YP_001185914.1 PFAM: CheB methylesterase YP_001185915.1 PFAM: CheW domain protein YP_001185916.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter YP_001185917.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001185918.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001185919.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001185920.1 PFAM: iron-containing alcohol dehydrogenase YP_001185921.1 PFAM: Gluconate transporter; Citrate transporter YP_001185922.1 PFAM: regulatory protein, IclR YP_001185923.1 PFAM: cytochrome B561 YP_001185924.1 PFAM: YceI family protein YP_001185925.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001185926.1 SMART: extracellular solute-binding protein, family 3 YP_001185927.1 PFAM: conserved hypothetical protein 730 YP_001185930.1 TIGRFAM: recA protein; PFAM: RecA domain protein; SMART: AAA ATPase YP_001185932.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001185933.1 PFAM: regulatory protein, LuxR YP_001185934.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase YP_001185935.1 PFAM: transposase IS66 YP_001185936.1 PFAM: IS66 Orf2 family protein YP_001185937.1 PFAM: IS66 Orf2 family protein YP_001185938.1 PFAM: transposase IS66 YP_001185939.1 PFAM: IS66 Orf2 family protein YP_001185940.1 PFAM: OmpW family protein YP_001185941.1 PFAM: AMP-dependent synthetase and ligase YP_001185942.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001185943.1 PFAM: aldehyde dehydrogenase YP_001185944.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001185945.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001185946.1 PFAM: fatty acid desaturase YP_001185950.1 TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_001185951.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001185954.1 PFAM: protein of unknown function DUF1090 YP_001185955.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_001185956.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001185957.1 PFAM: regulatory protein, ArsR; Methyltransferase type 11; Methyltransferase type 12 YP_001185958.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001185959.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein YP_001185960.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001185961.1 TIGRFAM: D-erythrose-4-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001185962.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001185964.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001185967.1 PFAM: glucose sorbosone dehydrogenase YP_001185968.1 PFAM: protein of unknown function DUF45 YP_001185971.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001185972.1 TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893, YccS/YhfK YP_001185973.1 PFAM: protein of unknown function DUF107 YP_001185974.1 PFAM: band 7 protein YP_001185975.1 TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein YP_001185976.1 PFAM: intradiol ring-cleavage dioxygenase YP_001185977.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001185978.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001185979.1 SMART: extracellular solute-binding protein, family 3 YP_001185980.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver YP_001185981.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001185982.1 PFAM: major facilitator superfamily MFS_1 YP_001185983.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001185984.1 catalyzes the formation of betaine from betaine aldehyde YP_001185985.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001185986.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001185987.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001185988.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001185989.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_001185990.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001185992.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001185994.1 PFAM: electron transfer flavoprotein beta-subunit YP_001185995.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit YP_001185996.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001185997.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001185999.1 PFAM: peptidase M19, renal dipeptidase YP_001186000.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001186001.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001186002.1 PFAM: protein of unknown function DUF849 YP_001186003.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001186005.1 TIGRFAM: gamma-butyrobetaine hydroxylase; PFAM: Taurine catabolism dioxygenase TauD/TfdA YP_001186006.1 PFAM: protein of unknown function UPF0153 YP_001186009.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein YP_001186010.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001186011.1 PFAM: protein of unknown function DUF924 YP_001186013.1 PFAM: Lipocalin family protein YP_001186015.1 TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold YP_001186016.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001186017.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001186018.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase YP_001186019.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106 YP_001186020.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106 YP_001186021.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001186022.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001186023.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein YP_001186024.1 PFAM: protein of unknown function DUF1243 YP_001186025.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001186026.1 TIGRFAM: putative polyhydroxyalkanoic acid system protein YP_001186027.1 TIGRFAM: poly(hydroxyalkanoate) granule-associated protein; PFAM: poly granule associated family protein YP_001186028.1 TIGRFAM: poly(hydroxyalkanoate) granule-associated protein; PFAM: poly granule associated family protein YP_001186029.1 PFAM: regulatory protein, TetR YP_001186030.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class II; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein YP_001186031.1 TIGRFAM: poly(3-hydroxyalkanoate) depolymerase; PFAM: alpha/beta hydrolase fold YP_001186032.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class II; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein YP_001186033.1 PFAM: protein of unknown function DUF971 YP_001186034.1 heat shock protein involved in degradation of misfolded proteins YP_001186035.1 heat shock protein involved in degradation of misfolded proteins YP_001186036.1 PFAM: Sporulation domain protein YP_001186037.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001186038.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001186039.1 PFAM: ribosomal protein L31 YP_001186040.1 PFAM: nuclease (SNase domain protein) YP_001186041.1 PFAM: peptidase M48, Ste24p YP_001186042.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding YP_001186043.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001186044.1 TIGRFAM: type IV pilus assembly protein PilM YP_001186045.1 PFAM: Fimbrial assembly family protein YP_001186046.1 PFAM: Pilus assembly protein, PilO YP_001186047.1 PFAM: Pilus assembly protein, PilQ YP_001186048.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain YP_001186049.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001186050.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001186051.1 PFAM: Sporulation domain protein YP_001186052.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001186053.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001186054.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001186055.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001186056.1 PFAM: UspA domain protein YP_001186058.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001186059.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001186060.1 PFAM: protein of unknown function UPF0061 YP_001186061.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_001186062.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001186063.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001186064.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001186065.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase YP_001186066.1 PFAM: restriction modification system DNA specificity domain YP_001186068.1 PFAM: Appr-1-p processing domain protein YP_001186069.1 TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001186070.1 PFAM: protein of unknown function DUF45 YP_001186071.1 PFAM: protein of unknown function DUF519 YP_001186072.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain YP_001186074.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001186075.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001186077.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_001186078.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001186079.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001186080.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001186081.1 TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase, family 9 YP_001186082.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase, family 9 YP_001186083.1 PFAM: glycosyl transferase, group 1 YP_001186084.1 PFAM: lipopolysaccharide kinase YP_001186085.1 PFAM: lipopolysaccharide kinase YP_001186086.1 PFAM: lipopolysaccharide kinase YP_001186088.1 PFAM: Carbamoyltransferase YP_001186089.1 PFAM: glycosyl transferase, group 1 YP_001186091.1 PFAM: glycosyl transferase, group 1 YP_001186092.1 PFAM: glycosyl transferase, family 2 YP_001186094.1 TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001186095.1 PFAM: Mig-14 family protein YP_001186096.1 PFAM: LmbE family protein YP_001186097.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001186098.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001186099.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001186100.1 PFAM: protein of unknown function DUF330 YP_001186101.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001186104.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001186105.1 PFAM: protein of unknown function UPF0227 YP_001186106.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase C-terminal domain protein YP_001186107.1 PFAM: protein of unknown function DUF1249 YP_001186108.1 PFAM: NUDIX hydrolase YP_001186109.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001186110.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein YP_001186111.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001186112.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186113.1 PFAM: small multidrug resistance protein YP_001186114.1 PFAM: FAD dependent oxidoreductase YP_001186115.1 PFAM: aldo/keto reductase YP_001186118.1 TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase, subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase, type 3 YP_001186119.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001186121.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001186122.1 PFAM: Rhodanese domain protein YP_001186123.1 PFAM: HDOD YP_001186124.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001186125.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001186126.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001186128.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001186129.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730 YP_001186130.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein YP_001186131.1 PFAM: protein of unknown function UPF0079 YP_001186132.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin YP_001186133.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001186134.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001186135.1 Stimulates the elongation of poly(A) tails YP_001186136.1 PFAM: GTP-binding protein, HSR1-related YP_001186137.1 TIGRFAM: HflK protein; PFAM: band 7 protein YP_001186138.1 TIGRFAM: HflC protein; PFAM: band 7 protein YP_001186140.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001186141.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001186142.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001186143.1 TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_001186144.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding YP_001186145.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001186146.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001186148.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001186149.1 unwinds double stranded DNA YP_001186150.1 TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein YP_001186151.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001186152.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001186155.1 PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein YP_001186156.1 PFAM: protein of unknown function DUF403; protein of unknown function DUF404; protein of unknown function DUF407 YP_001186157.1 PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein YP_001186158.1 TIGRFAM: Azurin; PFAM: blue (type 1) copper domain protein YP_001186159.1 PFAM: protein of unknown function DUF808 YP_001186160.1 PFAM: conserved hypothetical protein 730 YP_001186161.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001186162.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_001186163.1 PFAM: HupE/UreJ protein YP_001186164.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein, P47K YP_001186165.1 PFAM: Urease accessory protein UreF YP_001186166.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_001186167.1 PFAM: regulatory protein, TetR YP_001186168.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001186169.1 PFAM: fatty acid desaturase YP_001186171.1 PFAM: Auxin Efflux Carrier YP_001186172.1 PFAM: alpha/beta hydrolase fold YP_001186173.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component YP_001186174.1 PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001186175.1 PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001186176.1 PFAM: glutamine synthetase, catalytic region YP_001186177.1 PFAM: aldehyde dehydrogenase YP_001186178.1 PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase YP_001186186.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001186187.1 SMART: extracellular solute-binding protein, family 3 YP_001186188.1 PFAM: type II secretion system protein YP_001186190.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger, DksA/TraR C4-type YP_001186191.1 PFAM: Hemerythrin HHE cation binding domain protein YP_001186192.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001186193.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_001186194.1 PFAM: GCN5-related N-acetyltransferase YP_001186195.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001186196.1 PFAM: Urease accessory protein UreD YP_001186197.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186198.1 PFAM: ABC transporter related YP_001186199.1 PFAM: inner-membrane translocator YP_001186200.1 PFAM: inner-membrane translocator; SMART: PBS lyase HEAT domain protein repeat-containing protein YP_001186202.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001186203.1 TIGRFAM: urea amidolyase related protein; PFAM: biotin/lipoyl attachment domain-containing protein; Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp YP_001186204.1 catalyzes the hydrolysis of allophanate YP_001186205.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001186206.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001186207.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001186208.1 involved in de novo purine biosynthesis YP_001186209.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001186210.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS YP_001186211.1 TIGRFAM: MJ0042 family finger-like protein YP_001186212.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001186213.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001186214.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001186215.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001186216.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001186217.1 PFAM: chemotaxis sensory transducer YP_001186218.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein YP_001186219.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein YP_001186220.1 TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001186221.1 PFAM: Hemolysin-type calcium-binding region YP_001186222.1 PFAM: Hemolysin-type calcium-binding region YP_001186223.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver YP_001186225.1 PFAM: NUDIX hydrolase YP_001186226.1 PFAM: translation initiation factor SUI1 YP_001186227.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001186229.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE YP_001186230.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2 YP_001186231.1 PFAM: protein of unknown function DUF1568 YP_001186232.1 penicillin-insensitive transglycosylase/transpeptidase YP_001186234.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001186235.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001186236.1 PFAM: protein of unknown function DUF606 YP_001186237.1 PFAM: GCN5-related N-acetyltransferase YP_001186240.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001186242.1 PFAM: MaoC domain protein dehydratase YP_001186243.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001186244.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001186245.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001186246.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I YP_001186247.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II YP_001186249.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001186251.1 PFAM: methyltransferase small YP_001186252.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001186253.1 PFAM: protein of unknown function DUF465 YP_001186254.1 PFAM: protein of unknown function DUF465 YP_001186256.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001186257.1 PFAM: type IV pilus assembly PilZ YP_001186259.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001186260.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001186262.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001186263.1 PFAM: type IV pilus assembly PilZ YP_001186264.1 PFAM: protein of unknown function DUF1631 YP_001186265.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001186267.1 PFAM: MOSC domain containing protein YP_001186271.1 PFAM: protein of unknown function DUF329 YP_001186272.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001186273.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein YP_001186274.1 PFAM: type II secretion system protein YP_001186275.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein YP_001186276.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001186277.1 PFAM: Fimbrial protein pilin YP_001186278.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001186279.1 PFAM: protein of unknown function DUF1631 YP_001186280.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2 YP_001186282.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001186283.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease YP_001186284.1 PFAM: AsmA family protein YP_001186285.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001186286.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing enzyme; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001186287.1 PFAM: PfkB domain protein YP_001186288.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit YP_001186290.1 PFAM: Silent information regulator protein Sir2 YP_001186291.1 PFAM: Pyrrolo-quinoline quinone YP_001186292.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001186293.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase YP_001186294.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001186295.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001186296.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001186297.1 PFAM: periplasmic binding protein YP_001186298.1 PFAM: transport system permease protein YP_001186299.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186301.1 PFAM: Orn/DAP/Arg decarboxylase 2 YP_001186302.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001186303.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit YP_001186304.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase YP_001186305.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001186306.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001186307.1 PFAM: LamB/YcsF family protein YP_001186309.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase YP_001186310.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186311.1 PFAM: protein of unknown function RIO1 YP_001186312.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein, MerR YP_001186316.1 PFAM: lipase, class 3 YP_001186320.1 PFAM: Rhs element Vgr protein YP_001186321.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein YP_001186323.1 PFAM: Heavy metal transport/detoxification protein YP_001186324.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional repressor MAATS-type, C-terminal domain protein YP_001186325.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001186326.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001186327.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001186328.1 PFAM: protein of unknown function, zinc metallopeptidase putative YP_001186329.1 PFAM: protein of unknown function DUF411 YP_001186331.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001186332.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter YP_001186333.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein YP_001186334.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase; Ada, metal-binding domain protein; methylguanine DNA methyltransferase, ribonuclease domain protein YP_001186335.1 TIGRFAM: PAS sensor protein; PFAM: extracellular solute-binding protein, family 3; response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001186336.1 PFAM: response regulator receiver YP_001186337.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001186338.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001186339.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001186340.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001186341.1 PFAM: extracellular solute-binding protein, family 5 YP_001186342.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF861, cupin_3; Cupin 2, conserved barrel domain protein YP_001186343.1 PFAM: creatinase; peptidase M24 YP_001186344.1 PFAM: extracellular solute-binding protein, family 5 YP_001186345.1 PFAM: extracellular solute-binding protein, family 5 YP_001186346.1 PFAM: protein of unknown function DUF541 YP_001186347.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001186348.1 PFAM: response regulator receiver; helix-turn-helix, Fis-type YP_001186349.1 PFAM: Auxin Efflux Carrier YP_001186350.1 PFAM: Carboxymuconolactone decarboxylase YP_001186351.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region YP_001186352.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A YP_001186353.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001186354.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001186355.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001186356.1 functions in MreBCD complex in some organisms YP_001186357.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001186358.1 PFAM: Rod shape-determining protein MreD YP_001186359.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001186360.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein YP_001186362.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001186363.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001186364.1 PFAM: protein of unknown function DUF615 YP_001186365.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001186366.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein YP_001186367.1 PFAM: uncharacterised P-loop ATPase protein UPF0042 YP_001186368.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_001186369.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA YP_001186370.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001186371.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186372.1 PFAM: OstA family protein YP_001186373.1 PFAM: protein of unknown function DUF1239 YP_001186374.1 TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family YP_001186375.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001186376.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186377.1 PFAM: protein of unknown function DUF140 YP_001186378.1 PFAM: Mammalian cell entry related domain protein YP_001186379.1 PFAM: toluene tolerance family protein YP_001186380.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001186381.1 PFAM: BolA family protein YP_001186382.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001186383.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001186384.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001186385.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001186387.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001186388.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001186389.1 PFAM: protein of unknown function DUF34 YP_001186390.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001186391.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis YP_001186392.1 PFAM: protein of unknown function DUF1043 YP_001186394.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001186395.1 PFAM: AFG1-family ATPase YP_001186397.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001186398.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001186399.1 PFAM: Endonuclease V YP_001186400.1 PFAM: aldo/keto reductase YP_001186401.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001186402.1 forms a direct contact with the tRNA during translation YP_001186403.1 TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001186404.1 PFAM: Cytochrome b/b6, N-terminal domain; Cytochrome b/b6, C-terminal domain YP_001186406.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001186407.1 PFAM: Stringent starvation protein B YP_001186408.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria YP_001186409.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001186410.1 PFAM: protein of unknown function UPF0102 YP_001186411.1 PFAM: LppC family lipoprotein YP_001186412.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001186413.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001186414.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase YP_001186415.1 PFAM: cell division protein FtsL YP_001186416.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001186417.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001186418.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001186419.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001186420.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001186421.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein YP_001186422.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001186423.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001186424.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001186425.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type YP_001186426.1 PFAM: cell division protein FtsA YP_001186427.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001186428.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001186430.1 PFAM: peptidase M23B YP_001186431.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_001186432.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001186433.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001186434.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; thiamine monophosphate synthase YP_001186435.1 TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase YP_001186436.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001186437.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate YP_001186438.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver YP_001186439.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001186440.1 PFAM: MscS Mechanosensitive ion channel YP_001186442.1 PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001186445.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease YP_001186446.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001186447.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively YP_001186448.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001186450.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001186451.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein YP_001186452.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001186453.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001186454.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001186455.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001186456.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001186461.1 TIGRFAM: type IV pilus modification protein PilV YP_001186464.1 TIGRFAM: glycine oxidase ThiO; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase YP_001186465.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001186466.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001186469.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001186470.1 PFAM: protein of unknown function DUF152 YP_001186471.1 PFAM: regulatory protein, TetR YP_001186472.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001186474.1 PFAM: glycosyl transferase, group 1 YP_001186476.1 putative role in sulfur assimilation YP_001186477.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; CHASE4 domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001186478.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001186487.1 TIGRFAM: carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001186488.1 PFAM: Saccharopine dehydrogenase YP_001186489.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001186491.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase YP_001186492.1 PFAM: Rieske [2Fe-2S] domain protein YP_001186493.1 PFAM: periplasmic binding protein YP_001186494.1 PFAM: transport system permease protein YP_001186495.1 with HmuTU is involved in the transport of hemin YP_001186496.1 PFAM: protein of unknown function DUF399 YP_001186498.1 PFAM: cyclic nucleotide-binding YP_001186499.1 PFAM: TfoX, C-terminal domain protein YP_001186500.1 PFAM: pentapeptide repeat protein YP_001186502.1 TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001186503.1 PFAM: Tetratricopeptide TPR_4 YP_001186504.1 PFAM: protein of unknown function DUF446 YP_001186506.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit YP_001186507.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001186508.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001186509.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001186510.1 TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001186511.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001186512.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001186513.1 PFAM: Paraquat-inducible protein A YP_001186514.1 PFAM: Paraquat-inducible protein A YP_001186515.1 PFAM: Mammalian cell entry related domain protein YP_001186516.1 PFAM: SMC domain protein YP_001186518.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001186520.1 TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II; Nucleotidyl transferase; Cupin 2, conserved barrel domain protein YP_001186523.1 PFAM: membrane bound O-acyl transferase, MBOAT family protein YP_001186524.1 Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond: may enhance the production of alginate by controlling the length of the polymer chain during export YP_001186526.1 SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis YP_001186528.1 PFAM: Sel1 domain protein repeat-containing protein YP_001186529.1 PFAM: type IV pilus assembly PilZ YP_001186531.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase YP_001186532.1 PFAM: protein of unknown function DUF328 YP_001186533.1 PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc YP_001186534.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001186535.1 TIGRFAM: MoaD family protein; PFAM: thiamineS protein YP_001186536.1 PFAM: molybdopterin biosynthesis MoaE protein YP_001186538.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein YP_001186539.1 PFAM: protein of unknown function DUF6, transmembrane YP_001186545.1 PFAM: PilT protein domain protein YP_001186547.1 PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein YP_001186548.1 PFAM: IS66 Orf2 family protein YP_001186549.1 PFAM: transposase IS66 YP_001186551.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001186552.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001186553.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001186554.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001186555.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001186556.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001186557.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001186558.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001186559.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001186560.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; Methyltransferase type 11 YP_001186561.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001186562.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001186565.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001186566.1 PFAM: protein of unknown function DUF1365 YP_001186567.1 PFAM: amine oxidase; FAD dependent oxidoreductase YP_001186568.1 PFAM: short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KR YP_001186569.1 PFAM: protein of unknown function DUF1486 YP_001186570.1 PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein YP_001186571.1 PFAM: regulatory protein, MerR YP_001186572.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722 YP_001186574.1 PFAM: FAD dependent oxidoreductase YP_001186575.1 PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731 YP_001186576.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001186577.1 PFAM: major facilitator superfamily MFS_1 YP_001186579.1 SMART: extracellular solute-binding protein, family 3 YP_001186580.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein-like YP_001186581.1 PFAM: glutamine amidotransferase class-I; peptidase C26 YP_001186582.1 PFAM: protein of unknown function DUF6, transmembrane YP_001186583.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase YP_001186584.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001186585.1 SMART: Water Stress and Hypersensitive response YP_001186586.1 PFAM: protein of unknown function DUF6, transmembrane YP_001186587.1 PFAM: Phytanoyl-CoA dioxygenase YP_001186588.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS) YP_001186589.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186590.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase YP_001186591.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001186592.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001186593.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein, family 3 YP_001186596.1 PFAM: outer membrane porin YP_001186597.1 PFAM: extracellular solute-binding protein, family 3 YP_001186598.1 TIGRFAM: cyanophycinase YP_001186599.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KR YP_001186600.1 PFAM: regulatory protein, TetR YP_001186601.1 PFAM: thioesterase superfamily protein YP_001186602.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001186603.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001186605.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001186606.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_001186607.1 catalyzes the degradation of arginine to citruline and ammonia YP_001186608.1 TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region YP_001186609.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001186612.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186613.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001186615.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001186616.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001186619.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001186620.1 PFAM: regulatory protein, ArsR YP_001186621.1 PFAM: protein of unknown function DUF479 YP_001186622.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein YP_001186623.1 PFAM: UspA domain protein YP_001186624.1 PFAM: phospholipid/glycerol acyltransferase YP_001186627.1 PFAM: beta-lactamase domain protein YP_001186628.1 PFAM: beta-lactamase YP_001186630.1 PFAM: YceI family protein YP_001186631.1 PFAM: phospholipase D/Transphosphatidylase YP_001186633.1 PFAM: protein of unknown function DUF1302 YP_001186634.1 PFAM: protein of unknown function DUF1329 YP_001186635.1 PFAM: regulatory protein, LuxR; SMART: Tetratricopeptide domain protein YP_001186636.1 PFAM: short chain fatty acid transporter YP_001186637.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001186638.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001186639.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001186640.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186642.1 PFAM: ThiJ/PfpI domain protein YP_001186643.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001186644.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186645.1 PFAM: OsmC family protein; protein of unknown function DUF181 YP_001186646.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001186647.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001186648.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001186649.1 PFAM: extracellular solute-binding protein, family 1 YP_001186650.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001186651.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001186652.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001186653.1 PFAM: porin, LamB type YP_001186654.1 PFAM: Aldose 1-epimerase YP_001186655.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186656.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186658.1 PFAM: regulatory protein, MerR; Prophage CP4-57 regulatory YP_001186660.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001186661.1 PFAM: transposase IS66 YP_001186662.1 PFAM: IS66 Orf2 family protein YP_001186664.1 PFAM: phosphate-selective porin O and P YP_001186665.1 PFAM: regulatory protein, LysR YP_001186666.1 PFAM: outer membrane porin YP_001186667.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001186668.1 PFAM: outer membrane porin YP_001186670.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001186671.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001186672.1 PFAM: outer membrane efflux protein YP_001186673.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001186674.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein YP_001186677.1 PFAM: helix-turn-helix domain protein YP_001186678.1 PFAM: DNA repair protein RadC YP_001186684.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001186685.1 PFAM: phage integrase family protein YP_001186686.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Cache domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001186688.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester YP_001186690.1 PFAM: protein of unknown function UPF0027 YP_001186692.1 PFAM: band 7 protein YP_001186693.1 PFAM: sigma-54 factor, interaction domain-containing protein; regulator of RNA terminal phosphate cyclase; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001186696.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger YP_001186699.1 PFAM: Uncharacterized protein UPF0114 YP_001186701.1 PFAM: deoxyribodipyrimidine photolyase-related protein YP_001186703.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type YP_001186705.1 MexW; inner membrane protein; member of RND (resistance, nodulation, and division) family; involved in resistance to fluoroquinolones, tetracycline, chloramphenicol, erythromycin, ethidium bromide, and acriflavine; functions along with MexV and OprM YP_001186706.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001186707.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001186708.1 PFAM: protein of unknown function DUF112, transmembrane YP_001186710.1 PFAM: Uncharacterized protein UPF0065 YP_001186711.1 PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein YP_001186712.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate YP_001186713.1 PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein YP_001186714.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1 YP_001186715.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain YP_001186716.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001186717.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186718.1 PFAM: ABC-2 type transporter YP_001186720.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001186722.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001186724.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein YP_001186726.1 PFAM: globin YP_001186727.1 TIGRFAM: phosphoheptose isomerase; PFAM: sugar isomerase (SIS) YP_001186728.1 catalyzes the removal of amino acids from the N termini of peptides YP_001186729.1 PFAM: pseudouridine synthase YP_001186730.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001186731.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase YP_001186732.1 blocks the formation of polar Z-ring septums YP_001186733.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001186734.1 PFAM: Patatin YP_001186735.1 PFAM: Pirin domain protein domain protein; Pirin domain protein YP_001186736.1 PFAM: VacJ family lipoprotein YP_001186738.1 PFAM: GCN5-related N-acetyltransferase YP_001186741.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001186742.1 PFAM: major facilitator superfamily MFS_1 YP_001186744.1 PFAM: protein of unknown function UPF0060 YP_001186745.1 PFAM: phosphate-selective porin O and P YP_001186746.1 PFAM: protein of unknown function DUF482 YP_001186747.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter YP_001186751.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001186752.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001186753.1 PFAM: aldo/keto reductase YP_001186755.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001186756.1 PFAM: thioesterase superfamily protein YP_001186757.1 PFAM: outer membrane porin YP_001186758.1 PFAM: histidine triad (HIT) protein YP_001186759.1 PFAM: SlyX family protein YP_001186760.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001186761.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001186762.1 PFAM: Ferritin, Dps family protein YP_001186763.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001186764.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; Hpt domain protein YP_001186765.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001186766.1 PFAM: protein of unknown function DUF28 YP_001186767.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001186768.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001186769.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001186770.1 TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein YP_001186771.1 PFAM: MotA/TolQ/ExbB proton channel YP_001186772.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001186773.1 TIGRFAM: TonB family protein; PFAM: TolA family protein YP_001186774.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001186775.1 TIGRFAM: OmpA domain protein; PFAM: OmpA/MotB domain protein YP_001186776.1 PFAM: Tetratricopeptide TPR_2 repeat protein YP_001186777.1 PFAM: Radical SAM domain protein YP_001186778.1 TIGRFAM: exsB protein; PFAM: ExsB family protein YP_001186779.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001186780.1 PFAM: conserved hypothetical protein 730 YP_001186781.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001186782.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase YP_001186785.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation YP_001186786.1 PFAM: DTW domain containing protein YP_001186787.1 PFAM: protein of unknown function DUF6, transmembrane YP_001186788.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001186789.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186790.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001186791.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001186792.1 PFAM: alpha/beta hydrolase fold YP_001186793.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186795.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase YP_001186796.1 PFAM: MotA/TolQ/ExbB proton channel YP_001186797.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001186798.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6, transmembrane YP_001186799.1 TIGRFAM: RarD protein, DMT superfamily transporter YP_001186800.1 PFAM: bifunctional deaminase-reductase domain protein YP_001186802.1 PFAM: MscS Mechanosensitive ion channel YP_001186803.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001186804.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186805.1 PFAM: membrane-bound metal-dependent hydrolase YP_001186806.1 PFAM: Class I peptide chain release factor YP_001186807.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001186808.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001186809.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001186810.1 Required for efficient pilin antigenic variation YP_001186811.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type YP_001186812.1 PFAM: protein of unknown function DUF1232 YP_001186814.1 PFAM: helix-turn-helix domain protein YP_001186816.1 PFAM: Sel1 domain protein repeat-containing protein YP_001186817.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein YP_001186818.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001186819.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001186820.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001186821.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A YP_001186822.1 PFAM: protein of unknown function DUF861, cupin_3; Cupin 2, conserved barrel domain protein YP_001186823.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186824.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490 YP_001186825.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001186826.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001186827.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001186830.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001186831.1 PFAM: DGPFAETKE family protein YP_001186832.1 PFAM: protein of unknown function DUF899, thioredoxin family protein YP_001186834.1 PFAM: Sel1 domain protein repeat-containing protein YP_001186835.1 PFAM: peptidase M14, carboxypeptidase A YP_001186836.1 PFAM: outer membrane porin YP_001186838.1 TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein, MerR; Redox-sensitive transcriptional activator SoxR YP_001186839.1 PFAM: NADPH-dependent FMN reductase YP_001186840.1 TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001186841.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001186842.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001186843.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001186844.1 PFAM: superoxide dismutase, copper/zinc binding YP_001186845.1 PFAM: sigma-54 factor, interaction domain-containing protein; SMART: AAA ATPase YP_001186847.1 PFAM: Endonuclease I YP_001186849.1 PFAM: MscS Mechanosensitive ion channel YP_001186850.1 PFAM: chemotaxis sensory transducer YP_001186851.1 PFAM: alpha/beta hydrolase fold YP_001186852.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001186854.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001186855.1 TIGRFAM: urea amidolyase related protein; biotin carboxylation domain protein; PFAM: biotin/lipoyl attachment domain-containing protein; Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001186859.1 PFAM: 2OG-Fe(II) oxygenase YP_001186861.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186862.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001186865.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186866.1 PFAM: beta-lactamase domain protein YP_001186867.1 PFAM: protein of unknown function DUF1145 YP_001186868.1 TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding YP_001186870.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001186871.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001186872.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001186873.1 PFAM: Extracellular ligand-binding receptor YP_001186874.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001186875.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; Cupin 2, conserved barrel domain protein YP_001186876.1 PFAM: thioesterase superfamily protein YP_001186877.1 PFAM: HDOD YP_001186878.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001186880.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001186881.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001186882.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001186883.1 PFAM: inner-membrane translocator YP_001186884.1 PFAM: Extracellular ligand-binding receptor YP_001186887.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein YP_001186888.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001186889.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001186890.1 PFAM: OmpA/MotB domain protein YP_001186891.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001186892.1 TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001186893.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein YP_001186895.1 TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001186896.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001186897.1 TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; PFAM: FMN-binding domain protein YP_001186898.1 TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein YP_001186899.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001186900.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001186901.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit YP_001186902.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001186903.1 PFAM: protein of unknown function DUF59 YP_001186904.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001186905.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001186907.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001186908.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001186909.1 PFAM: isochorismatase hydrolase YP_001186910.1 PFAM: NUDIX hydrolase YP_001186911.1 PFAM: peptidase S45, penicillin amidase YP_001186913.1 PFAM: SEC-C motif domain protein YP_001186914.1 SMART: Water Stress and Hypersensitive response YP_001186917.1 PFAM: SEC-C motif domain protein YP_001186919.1 PFAM: OmpA/MotB domain protein YP_001186920.1 PFAM: OmpA/MotB domain protein YP_001186921.1 PFAM: protein of unknown function DUF1145 YP_001186924.1 helicase involved in DNA repair and perhaps also replication YP_001186925.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit YP_001186926.1 PFAM: multiple resistance and pH regulation protein F YP_001186927.1 PFAM: cation antiporter YP_001186928.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001186929.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001186930.1 PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I); Na+/H+ antiporter MnhB subunit-related protein YP_001186931.1 PFAM: beta-lactamase YP_001186932.1 PFAM: OmpA/MotB domain protein YP_001186933.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001186934.1 PFAM: helix-turn-helix, Fis-type; sugar diacid recognition domain protein YP_001186935.1 PFAM: Gluconate transporter; Citrate transporter YP_001186936.1 PFAM: glycerate kinase YP_001186937.1 PFAM: 17 kDa surface antigen YP_001186938.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_001186939.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001186940.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001186941.1 PFAM: cation antiporter YP_001186942.1 PFAM: multiple resistance and pH regulation protein F YP_001186943.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001186944.1 PFAM: protein of unknown function DUF6, transmembrane YP_001186945.1 PFAM: GCN5-related N-acetyltransferase YP_001186947.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001186948.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001186950.1 PFAM: pseudouridine synthase YP_001186951.1 PFAM: putative ammonia monooxygenase YP_001186952.1 PFAM: protein of unknown function DUF112, transmembrane YP_001186954.1 PFAM: Uncharacterized protein UPF0065 YP_001186955.1 PFAM: outer membrane porin YP_001186956.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001186957.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Two-component sensor kinase N-terminal domain protein YP_001186958.1 SMART: extracellular solute-binding protein, family 3 YP_001186959.1 PFAM: HDOD YP_001186961.1 PFAM: protein of unknown function DUF339 YP_001186963.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001186964.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates genes involved in alginate biosynthesis YP_001186965.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein YP_001186966.1 PFAM: MucB/RseB family protein YP_001186967.1 PFAM: Positive regulator of sigma(E), RseC/MucC YP_001186968.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001186969.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001186970.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001186972.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001186973.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001186974.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001186975.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001186976.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001186978.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase, putative; Methyltransferase type 11; Methyltransferase type 12 YP_001186979.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001186980.1 PFAM: YhhN family protein YP_001186981.1 PFAM: sigma-70 region 2 domain protein; Tetratricopeptide TPR_2 repeat protein; Sigma-70, region 4 type 2 YP_001186982.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001186984.1 PFAM: 2OG-Fe(II) oxygenase YP_001186987.1 PFAM: Fusaric acid resistance protein conserved region YP_001186988.1 PFAM: protein of unknown function DUF1656 YP_001186989.1 PFAM: secretion protein HlyD family protein YP_001186990.1 PFAM: MaoC domain protein dehydratase YP_001186991.1 PFAM: alpha/beta hydrolase fold YP_001186992.1 Disruption of the fadD2 gene did not have any effect on the catabolism of acetic, butyric and longer fatty acids (aliphatic or aromatic); however, might be involved in the specific activation of other fatty acids and may be functional when FadD1 is inactivated. YP_001186993.1 activates fatty acids by binding to coenzyme A; involved in the beta-oxidation of n-alkanoic and n-phenylalkanoic acids YP_001186994.1 PFAM: major facilitator superfamily MFS_1 YP_001186995.1 PFAM: protein of unknown function DUF6, transmembrane YP_001186996.1 PFAM: regulatory protein, MarR YP_001186997.1 PFAM: regulatory protein, ArsR YP_001186998.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001186999.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001187001.1 PFAM: regulatory protein, LysR YP_001187002.1 PFAM: major facilitator superfamily MFS_1 YP_001187005.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001187006.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001187007.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187008.1 TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases-like YP_001187010.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001187011.1 PFAM: ThiJ/PfpI domain protein YP_001187013.1 PFAM: major facilitator superfamily MFS_1 YP_001187014.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter YP_001187015.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; regulatory protein, ArsR YP_001187016.1 PFAM: NADPH-dependent FMN reductase YP_001187018.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_001187019.1 PFAM: major facilitator superfamily MFS_1 YP_001187021.1 TIGRFAM: citrate/H+ symporter, CitMHS family; PFAM: Citrate transporter YP_001187023.1 PFAM: major facilitator superfamily MFS_1 YP_001187024.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187025.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001187026.1 PFAM: major facilitator superfamily MFS_1 YP_001187027.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001187028.1 PFAM: histidine triad (HIT) protein YP_001187031.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001187036.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001187037.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC YP_001187040.1 PFAM: ferredoxin-dependent glutamate synthase YP_001187041.1 catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001187042.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001187044.1 PFAM: transposase IS66 YP_001187045.1 PFAM: IS66 Orf2 family protein YP_001187050.1 PFAM: protein of unknown function DUF692 YP_001187052.1 PFAM: DoxX family protein YP_001187053.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001187054.1 PFAM: FAD linked oxidase domain protein YP_001187055.1 PFAM: FAD dependent oxidoreductase YP_001187056.1 PFAM: carbohydrate kinase, FGGY YP_001187057.1 PFAM: Pirin domain protein domain protein; Cupin 2, conserved barrel domain protein YP_001187058.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001187059.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001187060.1 PFAM: CheB methylesterase; response regulator receiver YP_001187061.1 PFAM: MCP methyltransferase, CheR-type YP_001187062.1 PFAM: CheW domain protein YP_001187063.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001187064.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001187066.1 PFAM: response regulator receiver YP_001187067.1 PFAM: chemotaxis sensory transducer YP_001187068.1 PFAM: response regulator receiver; CheW domain protein YP_001187069.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein YP_001187071.1 PFAM: Lytic transglycosylase, catalytic YP_001187072.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001187074.1 PFAM: UspA domain protein YP_001187076.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001187077.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001187078.1 PFAM: protein of unknown function DUF1653 YP_001187079.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001187083.1 Represses a number of genes involved in the response to DNA damage YP_001187084.1 PFAM: regulatory protein, TetR YP_001187085.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein YP_001187086.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001187087.1 Catalyzes the phosphorolytic cleavage of 6-oxopurine nucleosides YP_001187089.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001187090.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001187091.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001187092.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001187093.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001187094.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001187095.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001187096.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001187097.1 PFAM: ApbE family lipoprotein YP_001187098.1 PFAM: protein of unknown function DUF539 YP_001187099.1 catalyzes the conversion of NADPH to NADH YP_001187100.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_001187102.1 PFAM: type IV pilus assembly PilZ YP_001187103.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214 YP_001187104.1 TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase YP_001187105.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214 YP_001187107.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein YP_001187108.1 PFAM: MotA/TolQ/ExbB proton channel YP_001187109.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001187110.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001187111.1 PFAM: protein of unknown function DUF343 YP_001187112.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001187113.1 PFAM: low molecular weight phosphotyrosine protein phosphatase YP_001187114.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001187115.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein YP_001187116.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001187117.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001187118.1 TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49 YP_001187119.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001187120.1 PFAM: protein of unknown function DUF177 YP_001187121.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001187122.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001187123.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein YP_001187124.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001187125.1 carries the fatty acid chain in fatty acid biosynthesis YP_001187126.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001187127.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001187128.1 PFAM: aminodeoxychorismate lyase YP_001187129.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001187130.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001187131.1 PFAM: type IV pilus assembly PilZ YP_001187132.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease YP_001187133.1 PFAM: aminotransferase, class V YP_001187134.1 PFAM: regulatory protein, TetR YP_001187135.1 PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001187136.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001187138.1 PFAM: protein of unknown function DUF1285 YP_001187139.1 PFAM: GCN5-related N-acetyltransferase YP_001187141.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001187142.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001187143.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein YP_001187146.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001187147.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001187149.1 PFAM: protein of unknown function UPF0118 YP_001187150.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001187151.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001187153.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001187154.1 PFAM: peptidase M48, Ste24p YP_001187155.1 PFAM: SirA family protein YP_001187156.1 PFAM: protein of unknown function UPF0118 YP_001187157.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001187159.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001187161.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001187164.1 Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond: may enhance the production of alginate by controlling the length of the polymer chain during export YP_001187168.1 PFAM: membrane bound O-acyl transferase, MBOAT family protein YP_001187171.1 PFAM: type IV pilus assembly PilZ YP_001187173.1 TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II; Nucleotidyl transferase; Cupin 2, conserved barrel domain protein YP_001187174.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001187175.1 PFAM: acriflavin resistance protein YP_001187176.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001187177.1 PFAM: regulatory protein, TetR YP_001187178.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187179.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001187180.1 PFAM: alpha/beta hydrolase fold YP_001187182.1 PFAM: protein of unknown function DUF6, transmembrane YP_001187184.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase YP_001187185.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001187188.1 PFAM: BolA family protein YP_001187189.1 PFAM: Rhodanese domain protein YP_001187190.1 PFAM: DSBA oxidoreductase YP_001187191.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001187192.1 TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001187193.1 PFAM: homogentisate 1,2-dioxygenase YP_001187194.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001187195.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain YP_001187196.1 PFAM: sodium:neurotransmitter symporter YP_001187197.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001187198.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001187199.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001187200.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001187201.1 PFAM: protein of unknown function UPF0066 YP_001187203.1 PFAM: RNA-binding S4 domain protein YP_001187204.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001187205.1 PFAM: UDP-N-acetylglucosamine 2-epimerase YP_001187206.1 PFAM: General secretory system II, protein E domain protein YP_001187209.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001187210.1 PFAM: cytochrome B561 YP_001187211.1 PFAM: beta-lactamase domain protein YP_001187212.1 PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254 YP_001187214.1 PFAM: protein of unknown function DUF202 YP_001187215.1 PFAM: protein of unknown function DUF1329 YP_001187216.1 PFAM: protein of unknown function DUF1302 YP_001187217.1 PFAM: regulatory protein, MarR; regulatory protein, LysR; LysR, substrate-binding YP_001187218.1 PFAM: major facilitator superfamily MFS_1 YP_001187219.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001187220.1 PFAM: AMP-dependent synthetase and ligase YP_001187221.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001187222.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001187223.1 PFAM: protein of unknown function DUF306, Meta and HslJ YP_001187225.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001187226.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein YP_001187227.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001187228.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001187229.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001187230.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001187231.1 TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_001187232.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001187234.1 PFAM: Modulator of Rho-dependent transcription termination YP_001187235.1 PFAM: outer membrane porin YP_001187237.1 PFAM: glutaredoxin 2 YP_001187238.1 PFAM: protein of unknown function DUF903 YP_001187239.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001187240.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain YP_001187241.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV YP_001187242.1 PFAM: NLP/P60 protein YP_001187243.1 PFAM: NLP/P60 protein YP_001187244.1 PFAM: O-methyltransferase, family 3 YP_001187246.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001187247.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001187248.1 TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase YP_001187249.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001187250.1 cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase YP_001187251.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001187252.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001187253.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001187254.1 PFAM: Phosphoglycerate mutase YP_001187255.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001187256.1 PFAM: regulatory protein, MarR YP_001187257.1 PFAM: major facilitator superfamily MFS_1 YP_001187258.1 PFAM: glutathione peroxidase; Redoxin domain protein YP_001187260.1 PFAM: lipase chaperone YP_001187261.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001187262.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001187263.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation YP_001187265.1 PFAM: Rhodanese domain protein YP_001187266.1 PFAM: phospholipid/glycerol acyltransferase YP_001187267.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001187268.1 PFAM: Strictosidine synthase; SMP-30/Gluconolaconase/LRE domain protein YP_001187269.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease YP_001187270.1 PFAM: protein of unknown function DUF709 YP_001187271.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001187272.1 PFAM: protein of unknown function UPF0153 YP_001187274.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001187276.1 PFAM: cyclic nucleotide-binding YP_001187277.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller YP_001187279.1 PFAM: histidine triad (HIT) protein YP_001187280.1 PFAM: glutamine amidotransferase, class-II YP_001187284.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001187286.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001187287.1 PFAM: protein of unknown function DUF6, transmembrane YP_001187288.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001187289.1 PFAM: beta-lactamase domain protein YP_001187290.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001187291.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001187292.1 PFAM: nucleoside recognition domain protein YP_001187293.1 TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase YP_001187294.1 PFAM: EAL domain protein YP_001187295.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187296.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001187297.1 PFAM: DTW domain containing protein YP_001187298.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein YP_001187299.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001187300.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein YP_001187302.1 PFAM: Hemolysin-type calcium-binding region; von Willebrand factor, type A YP_001187304.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein YP_001187306.1 PFAM: protein of unknown function DUF454 YP_001187307.1 TIGRFAM: yecA family protein YP_001187308.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001187309.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001187310.1 PFAM: regulatory protein, MarR YP_001187311.1 PFAM: Peptidoglycan-binding LysM YP_001187312.1 PFAM: surface antigen (D15); Patatin; surface antigen variable number repeat protein YP_001187313.1 TIGRFAM: conserved hypothetical selenoprotein; PFAM: Selenoprotein W-related YP_001187314.1 PFAM: protein of unknown function DUF6, transmembrane YP_001187315.1 TIGRFAM: export-related chaperone CsaA; PFAM: t-RNA-binding domain protein YP_001187316.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001187317.1 PFAM: metallophosphoesterase YP_001187318.1 PFAM: glycosyl transferase, group 1 YP_001187319.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; MASE2 domain protein YP_001187321.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001187322.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter YP_001187323.1 PFAM: protein of unknown function UPF0153 YP_001187324.1 PFAM: nitroreductase YP_001187325.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001187326.1 PFAM: protein of unknown function, Spy-related YP_001187327.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001187329.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001187330.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein YP_001187331.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001187333.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001187334.1 PFAM: chromosome segregation and condensation protein ScpA YP_001187335.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB YP_001187336.1 PFAM: protein of unknown function DUF1289 YP_001187337.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001187338.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001187339.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001187340.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001187341.1 Involved in ubiquinone biosynthesis YP_001187342.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline YP_001187343.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_001187344.1 negatively supercoils closed circular double-stranded DNA YP_001187345.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001187346.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein YP_001187347.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001187348.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate and catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001187349.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001187350.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001187351.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001187352.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001187353.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase YP_001187354.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001187356.1 PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II YP_001187357.1 PFAM: Citrate transporter; TrkA-C domain protein YP_001187358.1 PFAM: adenylylsulfate kinase YP_001187359.1 PFAM: polysaccharide biosynthesis protein YP_001187362.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001187363.1 PFAM: glycosyl transferase, family 2 YP_001187364.1 PFAM: glycosyl transferase, group 1 YP_001187365.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase YP_001187367.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; Polysaccharide biosynthesis C-terminal domain protein YP_001187368.1 PFAM: UDP-N-acetylglucosamine 2-epimerase YP_001187369.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001187370.1 PFAM: glycosyl transferase, family 4 YP_001187372.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001187373.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain YP_001187374.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein YP_001187377.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001187378.1 PFAM: major facilitator superfamily MFS_1 YP_001187381.1 PFAM: Phosphoglycerate mutase YP_001187382.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; methylguanine DNA methyltransferase, ribonuclease domain protein YP_001187383.1 PFAM: HhH-GPD family protein; AlkA domain protein YP_001187384.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001187386.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001187387.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001187388.1 PFAM: protein of unknown function DUF1260 YP_001187389.1 PFAM: DinB family protein YP_001187390.1 PFAM: GCN5-related N-acetyltransferase YP_001187391.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001187392.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001187395.1 PFAM: protein of unknown function DUF1330 YP_001187396.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001187397.1 catalyzes the conversion of citrate to isocitrate YP_001187399.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001187401.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE YP_001187402.1 Required for the de novo synthesis of pyroxidine via the pdxA branch; catalyzes the formation of 3-hydroxy-4-phospho-hydroxy-alpha-ketobutyrate from erythronate-4-phosphate YP_001187403.1 PFAM: glutathione peroxidase YP_001187404.1 PFAM: regulatory protein, MarR YP_001187405.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001187406.1 PFAM: protein of unknown function DUF815 YP_001187407.1 PFAM: GAF domain protein YP_001187408.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain YP_001187411.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001187413.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001187414.1 PFAM: ABC-2 type transporter YP_001187415.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001187416.1 PFAM: acriflavin resistance protein YP_001187417.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001187420.1 PFAM: thioesterase superfamily protein YP_001187421.1 PFAM: VacJ family lipoprotein YP_001187422.1 PFAM: type IV pilus assembly PilZ YP_001187423.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001187424.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001187425.1 TIGRFAM: transaldolase; PFAM: Transaldolase YP_001187427.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase, DuS YP_001187428.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase. YP_001187431.1 TIGRFAM: coenzyme PQQ biosynthesis protein PqqF; PFAM: peptidase M16 domain protein YP_001187433.1 PFAM: domain of unknown function DUF1745 YP_001187434.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001187435.1 PFAM: GCN5-related N-acetyltransferase YP_001187436.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001187438.1 PFAM: ABC-2 type transporter YP_001187439.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001187440.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein YP_001187443.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001187444.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001187445.1 PFAM: PEBP family protein YP_001187446.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001187449.1 PFAM: pentapeptide repeat protein YP_001187450.1 PFAM: Pyrrolo-quinoline quinone YP_001187452.1 SMART: extracellular solute-binding protein, family 3 YP_001187454.1 PFAM: beta-lactamase domain protein YP_001187456.1 PFAM: Pyrrolo-quinoline quinone YP_001187457.1 PFAM: aldehyde dehydrogenase YP_001187458.1 Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis; probably provides the glutamate and tyrosine residues that are cross-linked and modified to form the coenzyme YP_001187459.1 possibly involved in transport of pyrroloquinoline quinone transport YP_001187460.1 Required in the synthesis of PPQ, but its exact function is unknown YP_001187461.1 with PqqC converts a biosynthetic intermediate to pyrroloquinoline quinone YP_001187462.1 TIGRFAM: coenzyme PQQ biosynthesis protein E; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001187463.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein YP_001187464.1 PFAM: iron-containing alcohol dehydrogenase YP_001187465.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein YP_001187468.1 PFAM: FAD dependent oxidoreductase YP_001187469.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001187470.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001187471.1 PFAM: ribosomal protein L35 YP_001187472.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001187473.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001187474.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001187475.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001187476.1 PFAM: regulatory protein, MerR YP_001187477.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein YP_001187478.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit YP_001187479.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase YP_001187480.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit; SMART: AAA ATPase YP_001187481.1 PFAM: transposase IS66 YP_001187482.1 PFAM: IS66 Orf2 family protein YP_001187483.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001187486.1 PFAM: Propeptide, PepSY amd peptidase M4 YP_001187487.1 PFAM: Propeptide, PepSY amd peptidase M4 YP_001187488.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001187489.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein YP_001187490.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase YP_001187491.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001187492.1 PFAM: Citrate transporter; Na+/H+ antiporter NhaC; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001187493.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001187494.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187495.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001187496.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001187498.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001187499.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187500.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001187501.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001187502.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor YP_001187503.1 catalyzes the formation of pyruvate from D-cysteine YP_001187504.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_001187505.1 PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding YP_001187506.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001187507.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187508.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001187509.1 PFAM: Endoribonuclease L-PSP YP_001187510.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187511.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187512.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001187515.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187516.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001187517.1 PFAM: Patatin YP_001187518.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001187519.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001187521.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase YP_001187522.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_001187523.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001187524.1 catalyzes the hydration of gamma-carboxygeranoyl-CoA to 3-hydroxy-gamma-carboxygeranoyl-CoA YP_001187525.1 PFAM: carboxyl transferase YP_001187526.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001187527.1 PFAM: regulatory protein, MerR YP_001187528.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001187529.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001187530.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001187531.1 PFAM: beta-lactamase YP_001187532.1 PFAM: regulatory protein, AsnC/Lrp family YP_001187533.1 PFAM: protein of unknown function DUF6, transmembrane YP_001187534.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase YP_001187535.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001187536.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001187537.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001187538.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001187540.1 PFAM: extracellular solute-binding protein, family 1 YP_001187541.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001187542.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001187543.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001187544.1 binds and unfolds substrates as part of the ClpXP protease YP_001187545.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001187546.1 PFAM: histone family protein DNA-binding protein YP_001187547.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001187548.1 PFAM: phospholipase D/Transphosphatidylase YP_001187549.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001187550.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001187551.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001187552.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001187553.1 PFAM: extracellular solute-binding protein, family 5 YP_001187554.1 PFAM: extracellular solute-binding protein, family 5 YP_001187555.1 PFAM: GAF domain protein; HDOD YP_001187556.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein YP_001187557.1 PFAM: beta-lactamase domain protein YP_001187559.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001187560.1 3'-5' exonuclease of DNA polymerase III YP_001187561.1 PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein YP_001187562.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001187564.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001187565.1 PFAM: protein of unknown function DUF81 YP_001187567.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001187568.1 PFAM: aminoglycoside phosphotransferase YP_001187569.1 TIGRFAM: alpha-L-glutamate ligase-like protein; PFAM: RimK domain protein ATP-grasp YP_001187571.1 PFAM: protein of unknown function DUF785 YP_001187572.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001187573.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001187574.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001187575.1 Catalyzes the conversion of citrate to isocitrate YP_001187576.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453 YP_001187577.1 PFAM: protein of unknown function DUF299 YP_001187578.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001187580.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001187581.1 PFAM: Mg2+ transporter protein, CorA family protein YP_001187583.1 PFAM: Conserved TM helix repeat-containing protein YP_001187584.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in Pseudomonas fluorescens and P. aeruginosa regulates outer membrane protein OprF expression YP_001187585.1 PFAM: OmpA/MotB domain protein; OmpF family protein YP_001187586.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_001187587.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein YP_001187588.1 TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001187589.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein YP_001187590.1 PFAM: protein kinase; protein phosphatase 2C domain protein; SMART: serine/threonine protein kinase YP_001187591.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1 YP_001187594.1 PFAM: sulfatase YP_001187596.1 TIGRFAM: nitrate ABC transporter, ATPase subunits C and D; PFAM: ABC transporter related; SMART: AAA ATPase YP_001187597.1 TIGRFAM: nitrate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001187601.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001187603.1 PFAM: phage integrase family protein YP_001187605.1 PFAM: Zonular occludens toxin YP_001187618.1 PFAM: plasmid stabilization system YP_001187619.1 TIGRFAM: putative addiction module antidote protein, CC2985 family YP_001187622.1 PFAM: Elongation factor P/YeiP protein; Elongation factor, KOW domain protein YP_001187623.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187624.1 PFAM: protein of unknown function DUF81 YP_001187625.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187626.1 PFAM: protein of unknown function DUF1127 YP_001187627.1 PFAM: protein of unknown function DUF6, transmembrane YP_001187629.1 PFAM: protein of unknown function DUF1006 YP_001187630.1 PFAM: protein of unknown function DUF1311 YP_001187631.1 PFAM: peptidase M48, Ste24p YP_001187632.1 TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II YP_001187633.1 PFAM: Bile acid:sodium symporter YP_001187634.1 PFAM: flavin-containing monooxygenase FMO YP_001187636.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001187638.1 PFAM: uncharacterised conserved protein UCP030820 YP_001187639.1 PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001187641.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001187643.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001187644.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001187645.1 PFAM: FAD dependent oxidoreductase YP_001187646.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer YP_001187647.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001187650.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_001187651.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001187652.1 PFAM: fatty acid cistrans isomerase YP_001187653.1 PFAM: HesB/YadR/YfhF-family protein; nitrogen-fixing NifU domain protein YP_001187654.1 PFAM: HPP family protein+B94 YP_001187655.1 PFAM: protein of unknown function DUF1272 YP_001187656.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001187660.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001187661.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type YP_001187664.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC YP_001187666.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001187667.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001187668.1 PFAM: Cold-shock protein, DNA-binding; protein of unknown function DUF1294; SMART: Cold shock protein YP_001187669.1 PFAM: protein of unknown function DUF419 YP_001187670.1 streptomycin 3'-adenyltransferase YP_001187671.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001187672.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001187673.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001187674.1 PFAM: filamentation induced by cAMP protein Fic YP_001187675.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187676.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001187677.1 PFAM: response regulator receiver; CheW domain protein YP_001187678.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001187679.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region YP_001187680.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001187681.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001187682.1 PFAM: outer membrane porin YP_001187686.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like YP_001187687.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA YP_001187689.1 PFAM: cytochrome c, class I YP_001187690.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001187691.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001187692.1 PFAM: protein of unknown function DUF182 YP_001187693.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187694.1 PFAM: DinB family protein YP_001187695.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001187696.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187697.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187698.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KR YP_001187700.1 PFAM: CopG domain protein DNA-binding domain protein YP_001187702.1 PFAM: outer membrane efflux protein YP_001187703.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001187704.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein YP_001187706.1 PFAM: outer membrane porin YP_001187707.1 PFAM: protein of unknown function DUF411 YP_001187709.1 PFAM: copper resistance B precursor YP_001187711.1 TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001187714.1 PFAM: protein of unknown function DUF692 YP_001187717.1 PFAM: Heavy metal transport/detoxification protein YP_001187718.1 PFAM: transcriptional regulator PadR family protein YP_001187719.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter YP_001187720.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein YP_001187722.1 PFAM: blue (type 1) copper domain protein YP_001187725.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001187726.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001187733.1 PFAM: protein of unknown function DUF156 YP_001187734.1 PFAM: high-affinity nickel-transporter YP_001187736.1 PFAM: TraX family protein YP_001187737.1 SMART: Rhodanese domain protein YP_001187738.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter YP_001187740.1 PFAM: phage integrase family protein YP_001187748.1 PFAM: protein of unknown function DUF892 YP_001187750.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001187753.1 PFAM: peptidase S14, ClpP YP_001187756.1 TIGRFAM: cytochrome c, monohaem; PFAM: cytochrome c oxidase, subunit II YP_001187757.1 PFAM: cytochrome c oxidase, subunit I YP_001187763.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_001187765.1 PFAM: MscS Mechanosensitive ion channel YP_001187766.1 PFAM: CinA domain protein YP_001187767.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001187768.1 TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001187769.1 TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_001187770.1 TIGRFAM: malto-oligosyltrehalose synthase; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001187772.1 TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001187773.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001187774.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001187775.1 PFAM: phospholipase D/Transphosphatidylase YP_001187778.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35 YP_001187782.1 PFAM: CBS domain containing protein YP_001187783.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001187784.1 TIGRFAM: trehalose synthase; trehalose synthase-fused possible maltokinase; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001187785.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001187786.1 PFAM: MgtC/SapB transporter YP_001187787.1 PFAM: Rho termination factor domain protein YP_001187790.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001187791.1 PFAM: glutamate--cysteine ligase, GCS2 YP_001187793.1 PFAM: methyltransferase small YP_001187794.1 PFAM: Hemerythrin HHE cation binding domain protein YP_001187796.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001187797.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001187799.1 PFAM: 17 kDa surface antigen YP_001187800.1 PFAM: protein of unknown function DUF323 YP_001187801.1 PFAM: protein of unknown function DUF214 YP_001187802.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001187803.1 PFAM: protein kinase; tyrosine protein kinase; SMART: von Willebrand factor, type A; serine/threonine protein kinase YP_001187804.1 PFAM: protein phosphatase 2C domain protein YP_001187806.1 PFAM: ImcF domain protein; protein of unknown function DUF1215 YP_001187807.1 PFAM: OmpA/MotB domain protein YP_001187808.1 PFAM: protein of unknown function DUF876 YP_001187810.1 PFAM: Forkhead-associated protein YP_001187811.1 PFAM: ImpA domain protein YP_001187812.1 PFAM: uncharacterised conserved protein UCP028301 YP_001187813.1 PFAM: protein of unknown function DUF877 YP_001187814.1 PFAM: protein of unknown function DUF796 YP_001187817.1 PFAM: virulence protein, SciE type YP_001187818.1 PFAM: GPW/gp25 family protein YP_001187819.1 PFAM: protein of unknown function DUF879 YP_001187820.1 PFAM: protein of unknown function DUF1305 YP_001187821.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001187822.1 PFAM: Rhs element Vgr protein; Gp5 domain protein YP_001187825.1 catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP YP_001187829.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001187830.1 PFAM: glycosyl transferase, group 1 YP_001187831.1 PFAM: UDP-galactopyranose mutase YP_001187833.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001187835.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001187836.1 PFAM: molybdopterin dehydrogenase, FAD-binding YP_001187837.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001187838.1 PFAM: protein of unknown function DUF72 YP_001187839.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001187840.1 PFAM: protein of unknown function UPF0126 YP_001187841.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001187842.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001187843.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001187844.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; Ketopantoate reductase ApbA/PanE, N-terminal domain protein YP_001187845.1 catalyzes the formation of acetate from pyruvate YP_001187846.1 PFAM: sodium/hydrogen exchanger YP_001187847.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001187850.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001187851.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001187852.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001187854.1 PFAM: NLPA lipoprotein YP_001187855.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001187856.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001187857.1 PFAM: luciferase family protein YP_001187858.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger YP_001187860.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001187861.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001187862.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001187863.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001187864.1 PFAM: protein of unknown function UPF0005 YP_001187865.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001187866.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001187867.1 PFAM: DsrH family protein YP_001187868.1 PFAM: DsrC family protein YP_001187869.1 PFAM: glycosyl transferase, family 3 YP_001187870.1 PFAM: Glutathione S-transferase, C-terminal domain YP_001187871.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001187872.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001187873.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001187874.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001187875.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001187876.1 PFAM: cell divisionFtsK/SpoIIIE YP_001187877.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001187878.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001187879.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001187880.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001187881.1 TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001187882.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001187883.1 TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001187884.1 TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase YP_001187885.1 TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_001187886.1 PFAM: NUDIX hydrolase YP_001187887.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001187888.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001187889.1 PFAM: protein of unknown function DUF6, transmembrane YP_001187890.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001187891.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein YP_001187892.1 PFAM: GCN5-related N-acetyltransferase YP_001187894.1 PFAM: NolW domain protein YP_001187895.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_001187896.1 PFAM: protein of unknown function DUF839 YP_001187900.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187901.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001187902.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001187903.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187904.1 TIGRFAM: NADH-quinone oxidoreductase, F subunit; PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001187905.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187906.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187907.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187908.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187909.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187910.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001187911.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187912.1 Catalyzes the transfer of electrons from NADH to quinone YP_001187913.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001187914.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001187915.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein YP_001187916.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001187917.1 PFAM: acriflavin resistance protein YP_001187918.1 PFAM: acriflavin resistance protein YP_001187919.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001187920.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001187921.1 PFAM: protein of unknown function DUF490 YP_001187922.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein YP_001187923.1 PFAM: GCN5-related N-acetyltransferase YP_001187924.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001187925.1 PFAM: OmpA/MotB domain protein YP_001187926.1 PFAM: Integral membrane protein TerC YP_001187927.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001187928.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001187929.1 PFAM: DoxX family protein YP_001187930.1 PFAM: Lytic transglycosylase, catalytic YP_001187931.1 PFAM: TatD-related deoxyribonuclease YP_001187932.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001187935.1 PFAM: CHAD domain containing protein YP_001187936.1 PFAM: transglutaminase domain protein YP_001187937.1 PFAM: protein of unknown function DUF58 YP_001187938.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001187939.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001187942.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001187943.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001187944.1 PFAM: Patatin YP_001187945.1 PFAM: protein of unknown function UPF0118 YP_001187947.1 PFAM: alpha/beta hydrolase fold YP_001187948.1 PFAM: alpha/beta hydrolase fold YP_001187949.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001187950.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001187951.1 PFAM: thioesterase superfamily protein YP_001187952.1 PFAM: AMP-dependent synthetase and ligase YP_001187953.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase YP_001187955.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001187956.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001187957.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001187958.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001187959.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001187961.1 PFAM: Dual specificity protein phosphatase; putative tyrosine phosphatase YP_001187962.1 PFAM: phosphoesterase, PA-phosphatase related YP_001187963.1 PFAM: sulfatase YP_001187964.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001187965.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001187966.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001187967.1 PFAM: lipopolysaccharide kinase YP_001187968.1 PFAM: diacylglycerol kinase YP_001187970.1 PFAM: amidohydrolase 2 YP_001187971.1 PFAM: chemotaxis sensory transducer YP_001187972.1 PFAM: OsmC family protein YP_001187973.1 PFAM: Pirin domain protein domain protein; Pirin domain protein YP_001187975.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001187978.1 PFAM: dienelactone hydrolase YP_001187979.1 molecular chaperone YP_001187981.1 PFAM: thioesterase superfamily protein YP_001187982.1 PFAM: thioesterase superfamily protein YP_001187985.1 PFAM: protein of unknown function DUF599 YP_001187986.1 PFAM: branched-chain amino acid transport system II carrier protein YP_001187987.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001187988.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001187989.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001187990.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001187991.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001187992.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001187993.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001187995.1 PFAM: succinate dehydrogenase, cytochrome b subunit YP_001187996.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001187997.1 PFAM: lipid-binding START domain protein YP_001187998.1 PFAM: protein of unknown function UPF0153 YP_001187999.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001188000.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001188001.1 PFAM: protein of unknown function DUF1255 YP_001188002.1 PFAM: protein of unknown function DUF6, transmembrane YP_001188003.1 TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001188004.1 PFAM: DoxX family protein YP_001188005.1 PFAM: putative thiol-disulphide oxidoreductase DCC YP_001188006.1 PFAM: protein of unknown function DUF1287 YP_001188007.1 PFAM: ATP-NAD/AcoX kinase YP_001188009.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001188010.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001188012.1 putative metalloprotease YP_001188013.1 PFAM: thiopurine S-methyltransferase YP_001188014.1 PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B YP_001188015.1 PFAM: regulatory protein, TetR YP_001188017.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001188018.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001188019.1 PFAM: Phosphoglycerate mutase YP_001188020.1 PFAM: Sterol-binding domain protein YP_001188022.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation YP_001188024.1 PFAM: peptidase C39, bacteriocin processing YP_001188026.1 PFAM: regulatory protein, LuxR YP_001188027.1 PFAM: regulatory protein, LuxR; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001188028.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein YP_001188029.1 PFAM: fatty acid desaturase YP_001188030.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001188031.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001188032.1 catalyzes the formation of serine from phosphoserine; also has phosphoserine:homoserine phosphotransferase activity YP_001188033.1 PFAM: phosphoadenosine phosphosulfate reductase YP_001188034.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001188035.1 PFAM: UspA domain protein YP_001188036.1 PFAM: 5-nucleotidase YP_001188037.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate YP_001188039.1 PFAM: type IV pilus assembly PilZ YP_001188040.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001188042.1 PFAM: Gluconate transporter; Citrate transporter YP_001188044.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein YP_001188046.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001188047.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001188048.1 PFAM: protein of unknown function DUF214 YP_001188049.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001188051.1 TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase YP_001188052.1 PFAM: alpha/beta hydrolase fold YP_001188053.1 acts as a molecular chaperone to fold and export lipase A YP_001188054.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001188055.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001188056.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit YP_001188057.1 TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; Tripartite ATP-independent periplasmic transporter, DctQ component YP_001188058.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001188059.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001188060.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001188061.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001188062.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001188063.1 PFAM: tRNA--hydroxylase YP_001188064.1 PFAM: UspA domain protein YP_001188065.1 PFAM: protein of unknown function DUF1289 YP_001188066.2 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001188067.1 PFAM: protein of unknown function DUF903 YP_001188069.1 PFAM: response regulator receiver; ANTAR domain protein YP_001188071.1 PFAM: aminotransferase, class I and II YP_001188072.1 TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase YP_001188075.1 PFAM: glutamine amidotransferase class-I YP_001188078.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001188079.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001188080.1 PFAM: Rhodanese domain protein YP_001188082.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001188083.1 PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein YP_001188084.1 PFAM: protein of unknown function DUF403 YP_001188085.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407 YP_001188087.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; PFAM: cytochrome c oxidase, subunit I YP_001188088.1 CcoO; FixO YP_001188089.1 PFAM: Cbb3-type cytochrome oxidase component YP_001188090.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I YP_001188092.1 CcoN; FixN YP_001188093.1 CcoO; FixO YP_001188094.1 PFAM: Cbb3-type cytochrome oxidase component YP_001188095.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I YP_001188096.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001188098.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein YP_001188099.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type YP_001188101.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001188103.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001188104.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001188105.1 PFAM: Ion transport protein YP_001188107.1 PFAM: regulatory protein, TetR YP_001188109.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001188112.1 PFAM: DSBA oxidoreductase YP_001188113.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001188114.1 PFAM: regulatory protein, TetR YP_001188115.1 PFAM: protein of unknown function DUF480 YP_001188117.1 PFAM: regulatory protein, MarR YP_001188118.1 PFAM: OsmC family protein YP_001188120.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001188121.1 PFAM: aminotransferase class-III YP_001188122.1 PFAM: glutamine synthetase, catalytic region YP_001188123.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001188124.1 PFAM: FAD dependent oxidoreductase YP_001188125.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001188126.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein YP_001188127.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001188128.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism YP_001188129.1 PFAM: Rhodanese domain protein YP_001188130.1 PFAM: GCN5-related N-acetyltransferase YP_001188132.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001188133.1 PFAM: conserved hypothetical protein 103 YP_001188134.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001188137.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001188138.1 PFAM: histone family protein DNA-binding protein YP_001188139.1 PFAM: Sel1 domain protein repeat-containing protein; Tetratricopeptide TPR_2 repeat protein YP_001188140.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001188142.1 PFAM: blue (type 1) copper domain protein YP_001188143.1 PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001188144.1 PFAM: outer membrane efflux protein YP_001188147.1 TIGRFAM: arginine/ornithine antiporter; PFAM: Spore germination protein; amino acid permease-associated region YP_001188148.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001188149.1 PFAM: isochorismatase hydrolase YP_001188151.1 PFAM: Amidohydrolase 3 YP_001188152.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1 YP_001188154.1 PFAM: ATP-binding region, ATPase domain protein domain protein; Two component regulator propeller; Two component regulator three Y domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001188155.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001188156.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001188157.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain YP_001188158.1 PFAM: aminotransferase, class I and II YP_001188159.1 PFAM: regulatory protein, MarR YP_001188160.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in P. aeruginosa this sigma factor regulates the production of the ferrichrome outer membrane receptor FiuA. YP_001188161.1 PFAM: FecR protein YP_001188162.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001188164.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001188165.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease YP_001188166.1 PFAM: Bile acid:sodium symporter YP_001188167.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001188168.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001188169.1 PFAM: Ethanolamine ammonia lyase large subunit YP_001188170.1 PFAM: Ethanolamine ammonia-lyase light chain YP_001188172.1 PFAM: Abortive infection protein YP_001188173.1 SMART: extracellular solute-binding protein, family 3 YP_001188175.1 PFAM: regulatory protein, TetR YP_001188176.1 PFAM: protein of unknown function DUF1446 YP_001188177.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001188178.1 PFAM: carboxyl transferase YP_001188179.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001188180.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001188181.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001188182.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001188183.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization YP_001188186.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001188187.1 PFAM: von Willebrand factor, type A YP_001188188.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001188189.1 PFAM: OmpA/MotB domain protein YP_001188191.1 SMART: extracellular solute-binding protein, family 3 YP_001188192.1 PFAM: alpha/beta hydrolase fold YP_001188193.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit YP_001188194.1 PFAM: electron transfer flavoprotein beta-subunit YP_001188195.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase YP_001188196.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001188197.1 catalyzes the conversion of O-succinylhomoserine into homocysteine YP_001188198.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001188199.1 PFAM: Colicin V production protein YP_001188200.1 PFAM: Sporulation domain protein YP_001188201.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001188202.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001188203.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_001188204.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001188206.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001188207.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001188208.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001188209.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001188210.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001188211.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188212.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001188213.1 PFAM: heat shock protein Hsp20 YP_001188214.1 PFAM: dihydrouridine synthase, DuS YP_001188216.1 PFAM: thioesterase superfamily protein YP_001188217.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001188219.1 PFAM: regulatory protein, TetR YP_001188220.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001188221.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188222.1 PFAM: secretion protein HlyD family protein YP_001188223.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001188224.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001188225.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001188226.1 involved in methylation of ribosomal protein L3 YP_001188227.1 PFAM: Citrate transporter YP_001188228.1 PFAM: isochorismatase hydrolase YP_001188230.1 PFAM: Smr protein/MutS2 YP_001188231.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001188232.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain YP_001188233.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001188234.1 interacts directly with the cell division protein ftsZ; probable receptor for the septal ring structure, may anchor it to the inner-membrane YP_001188235.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain protein YP_001188236.1 PFAM: regulatory protein GntR, HTH YP_001188237.1 PFAM: fatty acid desaturase YP_001188238.1 PFAM: ferredoxin; molybdopterin dehydrogenase, FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein YP_001188239.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001188240.1 PFAM: protein of unknown function DUF182 YP_001188241.1 Catalyzes the deamination of guanine YP_001188242.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001188243.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter YP_001188244.1 PFAM: Transthyretin YP_001188245.1 PFAM: polysaccharide deacetylase YP_001188247.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001188248.1 PFAM: protein of unknown function DUF989 YP_001188249.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease YP_001188251.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001188253.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001188254.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional regulator YcdC, C-terminal domain protein YP_001188255.1 PFAM: protein of unknown function DUF336 YP_001188256.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001188257.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001188258.1 TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001188259.1 PFAM: MOFRL domain protein YP_001188260.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001188261.1 PFAM: Urea transporter YP_001188263.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001188264.1 PFAM: acriflavin resistance protein YP_001188265.1 TIGRFAM: efflux transporter, RND family, MFP subunit YP_001188267.1 PFAM: Ion transport protein; Ion transport 2 domain protein YP_001188268.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter YP_001188270.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001188271.1 PFAM: cytochrome C biogenesis protein YP_001188272.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001188273.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein YP_001188274.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001188275.1 PFAM: Heme exporter protein D (CcmD) YP_001188276.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein YP_001188277.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB YP_001188278.1 ATP-binding protein; required for proper cytochrome c maturation YP_001188281.1 SMART: Rhodanese domain protein YP_001188283.1 PFAM: CheW domain protein YP_001188284.1 PFAM: CheW domain protein YP_001188285.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001188286.1 Homologous to MotB. These organism have both MotB and MotD. With MotC (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. Either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility YP_001188287.1 homologous to MotA; this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility; these organisms have both MotA and MotC YP_001188288.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001188289.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001188290.1 PFAM: Chemotaxis phosphatase, CheZ YP_001188291.1 PFAM: response regulator receiver YP_001188292.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001188293.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001188294.1 positive regulator of class III flagellar genes YP_001188295.1 membrane protein involved in the flagellar export apparatus YP_001188296.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001188297.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001188298.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001188299.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001188300.1 PFAM: flagellar biosynthesis protein, FliO YP_001188301.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001188302.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001188303.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001188304.1 PFAM: flagellar hook-length control protein YP_001188305.1 PFAM: Hpt domain protein YP_001188306.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001188307.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001188308.1 rod/hook and filament chaperone YP_001188309.1 involved in type III protein export during flagellum assembly YP_001188310.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001188311.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001188312.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001188313.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_001188314.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001188315.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001188316.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; flagellar regulatory FleQ domain protein; SMART: AAA ATPase YP_001188318.1 flagellin specific chaperone YP_001188319.1 PFAM: flagellar protein FliS YP_001188320.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein YP_001188321.1 PFAM: flagellar protein FlaG protein YP_001188322.1 PFAM: flagellin domain protein YP_001188323.1 PFAM: glycosyl transferase, family 2; CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001188324.1 PFAM: Nucleotidyl transferase YP_001188325.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001188326.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001188327.1 With FlgK acts as a hook filament junction protein to join the flagellar filament to the hook YP_001188328.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001188329.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001188330.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001188331.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001188332.1 makes up the distal portion of the flagellar basal body rod YP_001188333.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001188334.1 the hook connects flagellar basal body to the flagellar filament YP_001188335.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001188336.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001188337.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001188338.1 PFAM: MCP methyltransferase, CheR-type YP_001188339.1 PFAM: response regulator receiver; CheW domain protein YP_001188340.1 required for the assembly of the flagellar basal body P-ring YP_001188341.1 PFAM: Anti-sigma-28 factor, FlgM family protein YP_001188342.1 PFAM: FlgN family protein YP_001188343.1 PFAM: type IV pilus assembly PilZ YP_001188344.1 PFAM: major facilitator superfamily MFS_1 YP_001188345.1 PFAM: glutamine synthetase, catalytic region YP_001188346.1 involved in the import of serine and threonine coupled with the import of sodium YP_001188347.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001188348.1 PFAM: ferric iron reductase YP_001188350.1 PFAM: Taurine catabolism dioxygenase TauD/TfdA YP_001188351.1 PFAM: MbtH domain protein YP_001188352.1 PFAM: periplasmic binding protein YP_001188353.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001188354.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001188355.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_001188356.1 TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding YP_001188357.1 TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding YP_001188359.1 TIGRFAM: cyclic peptide transporter; PFAM: ABC transporter related; SMART: AAA ATPase YP_001188360.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001188361.1 PFAM: sodium:neurotransmitter symporter YP_001188362.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001188363.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates YP_001188364.1 PFAM: regulatory protein, AsnC/Lrp family YP_001188365.1 required for the use of phosphonates and phosphite as phosphorus sources YP_001188366.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region YP_001188367.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3 YP_001188368.1 TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase YP_001188369.1 TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase YP_001188370.1 PFAM: phosphonate metabolism PhnJ YP_001188371.1 PFAM: phosphonate metabolism YP_001188372.1 PFAM: phosphonate metabolism YP_001188373.1 PFAM: phosphonate metabolism PhnG YP_001188374.1 TIGRFAM: phosphonates metabolism transcriptional regulator PhnF; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001188375.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001188376.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001188377.1 TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001188378.1 PFAM: Arc domain protein DNA binding domain protein YP_001188379.1 TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit YP_001188380.1 catalyzes the formation of pyruvate from oxaloacetate YP_001188381.1 PFAM: sodium pump decarboxylase, gamma subunit YP_001188382.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein YP_001188383.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001188386.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region YP_001188388.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001188389.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001188390.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001188391.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II YP_001188392.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001188394.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001188395.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001188396.1 PFAM: arginine N-succinyltransferase beta subunit YP_001188397.1 PFAM: arginine N-succinyltransferase beta subunit YP_001188398.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001188399.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001188400.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001188401.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001188402.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001188403.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein, family 3 YP_001188404.1 PFAM: General secretion pathway M protein YP_001188405.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L YP_001188406.1 PFAM: General secretion pathway protein K YP_001188407.1 TIGRFAM: general secretion pathway protein J YP_001188408.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J YP_001188409.1 TIGRFAM: general secretion pathway protein H YP_001188410.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G YP_001188411.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein YP_001188412.1 TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E YP_001188414.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein YP_001188415.1 PFAM: NAD-glutamate dehydrogenase YP_001188416.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001188417.1 PFAM: protein of unknown function DUF58 YP_001188419.1 PFAM: von Willebrand factor, type A YP_001188420.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001188422.1 PFAM: Patched family protein YP_001188423.1 related to photosystem II stability/assembly factor YP_001188424.1 PFAM: protein of unknown function DUF1329 YP_001188425.1 PFAM: protein of unknown function DUF1302 YP_001188426.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase YP_001188428.1 PFAM: protein of unknown function DUF1315 YP_001188429.1 PFAM: Rhomboid family protein YP_001188430.1 PFAM: metallophosphoesterase YP_001188431.1 catalyzes the phosphorylation of NAD to NADP YP_001188433.1 PFAM: cyclic nucleotide-binding; SMART: Rhodanese domain protein YP_001188436.1 TIGRFAM: TRAP transporter solute receptor, TAXI family YP_001188438.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein YP_001188439.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001188440.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001188441.1 PFAM: regulatory protein, MarR YP_001188442.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase YP_001188443.1 PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp YP_001188444.1 PFAM: peptidase M20; peptidase M42 family protein YP_001188445.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001188446.1 PFAM: protein of unknown function UPF0270 YP_001188448.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001188449.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001188450.1 PFAM: heat shock protein DnaJ domain protein YP_001188451.1 PFAM: protein of unknown function DUF1282 YP_001188452.1 PFAM: protein of unknown function DUF1282 YP_001188453.1 PFAM: protein of unknown function DUF335, SprT; SMART: protein of unknown function SprT YP_001188454.1 PFAM: protein of unknown function DUF1311 YP_001188456.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001188457.1 PFAM: AMP-dependent synthetase and ligase YP_001188458.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001188459.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001188461.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001188462.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001188463.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001188465.1 PFAM: major facilitator superfamily MFS_1 YP_001188466.1 PFAM: periplasmic nitrate reductase NapE YP_001188467.1 PFAM: NapD family protein YP_001188468.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001188469.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB) YP_001188470.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein YP_001188471.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001188472.1 PFAM: type IV pilus assembly PilZ YP_001188475.1 TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN YP_001188476.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related YP_001188477.1 PFAM: flavodoxin/nitric oxide synthase YP_001188480.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001188481.1 PFAM: protein of unknown function UPF0118 YP_001188483.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001188484.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001188486.1 PFAM: Rh family protein/ammonium transporter YP_001188487.1 PFAM: protein of unknown function DUF883, ElaB YP_001188490.1 PFAM: EAL domain protein YP_001188491.1 dGTPase family type 3 subfamily, presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001188493.1 PFAM: histidine kinase, HAMP region domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001188494.1 PFAM: protein of unknown function DUF469 YP_001188495.1 TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C YP_001188496.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001188497.1 PFAM: ribosome modulation factor YP_001188498.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001188501.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001188502.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001188503.1 PFAM: CinA domain protein YP_001188504.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001188505.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001188506.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001188507.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B YP_001188508.1 PFAM: protein of unknown function DUF368 YP_001188509.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001188510.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001188511.1 catalyzes the modification of U13 in tRNA(Glu) YP_001188512.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001188513.1 PFAM: putative esterase YP_001188514.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001188515.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188517.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001188518.1 PFAM: Septum formation initiator YP_001188519.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001188520.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001188521.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001188522.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; tRNA(Ile)-lysidine synthetase domain protein YP_001188523.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001188524.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001188525.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001188526.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001188527.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001188528.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001188529.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001188530.1 PFAM: outer membrane chaperone Skp (OmpH) YP_001188531.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein YP_001188532.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50 YP_001188533.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001188534.1 PFAM: phosphatidate cytidylyltransferase YP_001188535.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001188536.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001188537.1 Catalyzes the phosphorylation of UMP to UDP YP_001188538.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001188539.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001188540.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001188541.1 Catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001188542.1 catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate YP_001188544.1 PFAM: arsenate reductase and related YP_001188546.1 PFAM: aminotransferase, class V YP_001188547.1 PFAM: Fe-S metabolism associated SufE YP_001188548.1 PFAM: protein of unknown function DUF1456 YP_001188550.1 PFAM: UBA/THIF-type NAD/FAD binding protein YP_001188551.1 PFAM: iron-containing alcohol dehydrogenase YP_001188552.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001188553.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001188555.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001188559.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001188561.1 TIGRFAM: integron integrase YP_001188562.1 PFAM: GCN5-related N-acetyltransferase YP_001188565.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001188570.1 PFAM: transposase IS66 YP_001188571.1 PFAM: IS66 Orf2 family protein YP_001188573.1 PFAM: GCN5-related N-acetyltransferase YP_001188575.1 PFAM: protein of unknown function DUF6, transmembrane YP_001188577.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001188579.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001188580.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001188581.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001188582.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001188583.1 PFAM: SH3, type 3 domain protein; SMART: SH3 domain protein domain protein YP_001188584.1 PFAM: EAL domain protein YP_001188585.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188586.1 PFAM: beta-lactamase domain protein YP_001188587.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001188590.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001188593.1 PFAM: EAL domain protein YP_001188594.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001188595.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001188596.1 PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: PAS domain containing protein; AAA ATPase YP_001188597.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001188598.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001188599.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001188600.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001188601.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001188602.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001188603.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001188604.1 PFAM: major facilitator superfamily MFS_1 YP_001188605.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; glucosylglycerol-phosphate synthase; PFAM: glycosyl transferase, family 20; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase, type 3 YP_001188607.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase YP_001188608.1 PFAM: DGPFAETKE family protein YP_001188609.1 PFAM: alpha/beta hydrolase fold YP_001188611.1 PFAM: alpha/beta hydrolase fold YP_001188612.1 with malEFG is involved in import of maltose/maltodextrin YP_001188613.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001188614.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_001188615.1 with MalKFE is involved in the transport of maltose into the cell YP_001188616.1 with MalKGE is involved in maltose transport into the cell YP_001188617.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_001188618.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_001188620.1 PFAM: protein of unknown function DUF1568 YP_001188621.1 PFAM: glycoside hydrolase, starch-binding; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001188622.1 porin involved in the transport of maltose and maltodextrins YP_001188623.1 PFAM: Maltose operon periplasmic YP_001188624.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001188625.1 PFAM: aldo/keto reductase YP_001188626.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001188627.1 TIGRFAM: 6-phosphogluconolactonase YP_001188628.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001188629.1 Represses the expression of the zwf, eda, glp and gap YP_001188630.1 PFAM: Bile acid:sodium symporter YP_001188631.1 PFAM: small multidrug resistance protein YP_001188632.1 PFAM: phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1 YP_001188633.1 PFAM: 4'-phosphopantetheinyl transferase YP_001188634.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001188635.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001188636.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001188637.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001188640.1 PFAM: aldo/keto reductase YP_001188641.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188642.1 PFAM: protein of unknown function DUF1289 YP_001188644.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188645.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase YP_001188646.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001188648.1 PFAM: protein of unknown function DUF861, cupin_3 YP_001188649.1 PFAM: proteinase inhibitor I11, ecotin YP_001188650.1 TIGRFAM: yecA family protein; PFAM: SEC-C motif domain protein YP_001188651.1 PFAM: peptidase U32 YP_001188652.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001188653.1 PFAM: NAD(P)H dehydrogenase (quinone) YP_001188654.1 PFAM: Allergen V5/Tpx-1 family protein YP_001188656.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001188657.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001188658.1 PFAM: protein of unknown function DUF6, transmembrane YP_001188659.1 PFAM: protein of unknown function DUF81 YP_001188660.1 PFAM: protein of unknown function DUF1176 YP_001188661.1 PFAM: oxidoreductase domain protein; NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein YP_001188663.1 PFAM: protein of unknown function DUF28 YP_001188664.1 PFAM: NUDIX hydrolase YP_001188666.1 PFAM: Forkhead-associated protein YP_001188667.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase YP_001188668.1 PFAM: protein phosphatase 2C domain protein YP_001188669.1 PFAM: GCN5-related N-acetyltransferase YP_001188670.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001188672.1 SMART: RNA binding S1 domain protein YP_001188674.1 PFAM: glucose sorbosone dehydrogenase YP_001188675.1 SMART: extracellular solute-binding protein, family 3 YP_001188676.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001188677.1 PFAM: major facilitator superfamily MFS_1 YP_001188679.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein YP_001188680.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001188681.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding YP_001188682.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001188683.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001188684.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001188685.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001188686.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001188687.1 PFAM: aldehyde dehydrogenase YP_001188689.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; 4-vinyl reductase, 4VR; Activator of aromatic catabolism; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001188690.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001188691.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188693.1 PFAM: NAD(P)H dehydrogenase (quinone) YP_001188694.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188695.1 PFAM: major facilitator superfamily MFS_1 YP_001188697.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001188698.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188699.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein YP_001188700.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001188701.1 PFAM: Ku domain protein YP_001188702.1 catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001188703.1 PFAM: chemotaxis sensory transducer YP_001188704.1 PFAM: regulatory protein, MerR YP_001188706.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001188708.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001188709.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain YP_001188710.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188711.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188712.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001188713.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001188714.1 PFAM: protein of unknown function DUF344 YP_001188715.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001188716.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001188717.1 PFAM: protein of unknown function DUF6, transmembrane YP_001188718.1 PFAM: UvrD/REP helicase YP_001188719.1 PFAM: cytochrome B561 YP_001188720.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001188721.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001188722.1 PFAM: glycoside hydrolase, family 3 domain protein YP_001188723.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001188724.1 PFAM: SNF2-related protein; helicase domain protein; zinc finger, SWIM domain protein; SMART: DEAD-like helicases-like YP_001188725.1 PFAM: phosphate-starvation-inducible E YP_001188726.1 PFAM: YebG family protein YP_001188728.1 PFAM: protein of unknown function DUF488 YP_001188729.1 PFAM: protein of unknown function DUF6, transmembrane YP_001188730.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001188731.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001188732.1 PFAM: dehydrogenase, E1 component YP_001188733.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001188737.1 PFAM: secretion protein HlyD family protein YP_001188739.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001188740.1 SMART: extracellular solute-binding protein, family 3 YP_001188741.1 PFAM: type IV pilus assembly PilZ YP_001188745.1 PFAM: UspA domain protein YP_001188746.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001188747.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001188748.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001188749.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001188750.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region YP_001188751.1 catalyzes the formation of pyruvate from serine YP_001188752.1 PFAM: protein of unknown function DUF1028 YP_001188754.1 PFAM: AFG1-family ATPase YP_001188755.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001188757.1 PFAM: protein of unknown function DUF1486 YP_001188758.1 related to arylsulfate sulfotransferase involved in siderophore biosynthesis YP_001188759.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein YP_001188761.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001188762.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001188765.1 PFAM: alpha/beta hydrolase fold YP_001188766.1 PFAM: class II aldolase/adducin family protein YP_001188767.1 PFAM: protein of unknown function DUF985 YP_001188768.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001188769.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001188771.1 PFAM: regulatory protein, MerR YP_001188772.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001188773.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001188774.1 PFAM: GTP cyclohydrolase I YP_001188775.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001188776.1 PFAM: protein of unknown function DUF1244 YP_001188778.1 PFAM: protein of unknown function DUF1089 YP_001188779.1 PFAM: branched-chain amino acid transport YP_001188780.1 PFAM: AzlC family protein YP_001188781.1 PFAM: protein of unknown function DUF1111 YP_001188783.1 PFAM: uncharacterised conserved protein UCP028101 YP_001188784.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001188785.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein YP_001188786.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001188787.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component YP_001188788.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit YP_001188789.1 PFAM: protein of unknown function DUF6, transmembrane YP_001188790.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001188791.1 PFAM: Aldose 1-epimerase YP_001188793.1 PFAM: protein of unknown function DUF853, NPT hydrolase putative; SMART: AAA ATPase YP_001188794.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer YP_001188796.1 PFAM: CBS domain containing protein YP_001188797.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001188799.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001188800.1 PFAM: protein of unknown function DUF975 YP_001188801.1 PFAM: RDD domain containing protein YP_001188802.1 PFAM: protein of unknown function DUF95, transmembrane YP_001188805.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001188806.1 PFAM: protein of unknown function DUF58 YP_001188807.1 PFAM: manganese and iron superoxide dismutase YP_001188808.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001188810.1 PFAM: LemA family protein YP_001188812.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001188813.1 PFAM: GCN5-related N-acetyltransferase YP_001188814.1 PFAM: regulatory protein, MerR YP_001188815.1 PFAM: alpha/beta hydrolase fold YP_001188816.1 PFAM: protein of unknown function DUF195 YP_001188817.1 PFAM: Sel1 domain protein repeat-containing protein YP_001188822.1 PFAM: uncharacterised conserved protein UCP025560 YP_001188823.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin YP_001188824.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001188826.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001188827.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001188828.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein YP_001188829.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY YP_001188830.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001188831.1 PFAM: regulatory protein, DeoR; Bacterio-opsin activator, HTH domain protein; Helix-turn-helix, type 11 domain protein YP_001188832.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001188833.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein YP_001188834.1 PFAM: acriflavin resistance protein YP_001188835.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001188836.1 PFAM: regulatory protein, TetR YP_001188837.1 PFAM: protein of unknown function DUF548 YP_001188838.1 PFAM: Extensin family protein YP_001188839.1 PFAM: protein of unknown function DUF72 YP_001188841.1 PFAM: peptidase M22, glycoprotease YP_001188842.1 TIGRFAM: 5'-nucleotidase, lipoprotein e(P4) family; PFAM: acid phosphatase (Class B) YP_001188843.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001188844.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001188847.1 PFAM: OmpA/MotB domain protein YP_001188850.1 PFAM: protein of unknown function DUF124 YP_001188851.1 PFAM: protein of unknown function DUF1704 YP_001188853.1 PFAM: regulatory protein, TetR YP_001188854.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001188855.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein YP_001188856.1 PFAM: Autotransporter beta- domain protein YP_001188857.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase YP_001188858.1 TIGRFAM: sulfate transporter; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter YP_001188859.1 PFAM: protein of unknown function DUF533 YP_001188860.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1 YP_001188862.1 PFAM: LamB/YcsF family protein YP_001188863.1 PFAM: Allophanate hydrolase subunit 1 YP_001188864.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2 YP_001188866.1 PFAM: YaeQ family protein YP_001188869.1 PFAM: Rhomboid family protein YP_001188873.1 PFAM: PspA/IM30 family protein YP_001188875.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001188877.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001188878.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001188880.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001188882.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001188883.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001188884.1 Essential for efficient processing of 16S rRNA YP_001188885.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001188886.1 TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54, G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001188887.1 PFAM: cytochrome c assembly protein YP_001188888.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001188890.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001188891.1 PFAM: protein of unknown function DUF1289 YP_001188893.1 PFAM: NUDIX hydrolase YP_001188894.1 PFAM: NUDIX hydrolase YP_001188898.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001188899.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001188901.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001188902.1 PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001188910.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001188913.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001188914.1 PFAM: protein of unknown function UPF0153 YP_001188916.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001188918.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter YP_001188919.1 PFAM: protein of unknown function DUF1185 YP_001188920.1 PFAM: alpha/beta hydrolase fold; Ndr family protein YP_001188921.1 PFAM: aldehyde dehydrogenase YP_001188922.1 PFAM: flavin reductase domain protein, FMN-binding YP_001188923.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001188924.1 PFAM: Carboxymuconolactone decarboxylase YP_001188925.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001188926.1 PFAM: NUDIX hydrolase YP_001188927.1 PFAM: protein of unknown function DUF1330 YP_001188928.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis YP_001188929.1 PFAM: extracellular solute-binding protein, family 1 YP_001188930.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001188931.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001188932.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001188933.1 PFAM: flavin reductase domain protein, FMN-binding YP_001188934.1 PFAM: regulatory protein, LuxR; PAS fold-3 domain protein YP_001188936.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001188938.1 PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001188939.1 TIGRFAM: formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein YP_001188940.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001188941.1 PFAM: flavin-containing monooxygenase FMO YP_001188942.1 PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001188943.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein YP_001188944.1 PFAM: Rh family protein/ammonium transporter YP_001188946.1 PFAM: small multidrug resistance protein YP_001188947.1 PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; dihydroorotate dehydrogenase; ferredoxin-dependent glutamate synthase YP_001188948.1 PFAM: glutamate synthase, alpha subunit domain protein YP_001188949.1 PFAM: glutamine amidotransferase, class-II YP_001188950.1 PFAM: glutamine synthetase, catalytic region YP_001188951.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001188952.1 TIGRFAM: formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein YP_001188953.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001188954.1 PFAM: FAD dependent oxidoreductase YP_001188955.1 PFAM: Sarcosine oxidase, delta subunit, heterotetrameric YP_001188956.1 PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein, C-terminal barrel YP_001188958.1 PFAM: regulatory protein, IclR; Helix-turn-helix, type 11 domain protein YP_001188959.1 PFAM: luciferase family protein YP_001188960.1 PFAM: isochorismatase hydrolase YP_001188961.1 PFAM: Prophage CP4-57 regulatory YP_001188962.1 PFAM: Prophage CP4-57 regulatory YP_001188964.1 PFAM: phage integrase family protein YP_001188965.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001188966.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001188968.1 PFAM: transmembrane pair domain protein YP_001188969.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001188970.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001188971.1 PFAM: peptidase M23B YP_001188972.1 TIGRFAM: 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain YP_001188974.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001188975.1 catalyzes the transfer of an amino moiety YP_001188976.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001188977.1 PFAM: Pyrrolo-quinoline quinone YP_001188979.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001188980.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001188981.1 SMART: helix-turn-helix domain protein YP_001188982.1 TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001188983.1 TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein YP_001188984.1 PFAM: nucleoside diphosphate kinase YP_001188985.1 PFAM: protein of unknown function DUF528 YP_001188986.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin YP_001188987.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001188988.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001188989.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein YP_001188990.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein YP_001188991.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001188992.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074 YP_001188993.1 TIGRFAM: serine O-acetyltransferase YP_001188994.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001188995.1 PFAM: inositol monophosphatase YP_001188996.1 PFAM: 17 kDa surface antigen YP_001188997.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001188998.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001188999.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001189000.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001189001.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001189003.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001189004.1 PFAM: RDD domain containing protein YP_001189005.1 PFAM: permease YjgP/YjgQ family protein YP_001189006.1 PFAM: permease YjgP/YjgQ family protein YP_001189007.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001189008.1 PFAM: DNA polymerase III chi subunit, HolC YP_001189010.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001189011.1 PFAM: Na+/H+ antiporter NhaC YP_001189012.1 PFAM: Citrate transporter YP_001189014.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001189015.1 PFAM: protein of unknown function DUF890 YP_001189016.1 PFAM: Arsenical pump membrane protein; Citrate transporter YP_001189017.1 PFAM: isochorismatase hydrolase YP_001189018.1 PFAM: SMC domain protein YP_001189020.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001189021.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001189022.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_001189024.1 PFAM: amino acid permease-associated region YP_001189025.1 PFAM: regulatory protein, AsnC/Lrp family; regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein YP_001189026.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001189028.1 PFAM: peptidase M20; protease-associated PA domain protein; peptidase M28 YP_001189029.1 PFAM: 37kDa nucleoid-associated protein YP_001189030.1 PFAM: protein of unknown function DUF344 YP_001189031.1 PFAM: glutaredoxin YP_001189033.1 PFAM: Excinuclease ABC, C subunit domain protein YP_001189034.1 PFAM: CDP-alcohol phosphatidyltransferase YP_001189035.1 PFAM: protein of unknown function DUF1486 YP_001189036.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001189037.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001189038.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189039.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189040.1 PFAM: extracellular solute-binding protein, family 3 YP_001189041.1 PFAM: phospholipase/Carboxylesterase YP_001189042.1 activates fatty acids by binding to coenzyme A YP_001189043.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; cyclic nucleotide-binding YP_001189044.1 PFAM: amidohydrolase 2; peptidase M19, renal dipeptidase YP_001189045.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001189046.1 PFAM: ornithine cyclodeaminase/mu-crystallin YP_001189047.1 PFAM: FAD dependent oxidoreductase YP_001189048.1 PFAM: YheO domain protein YP_001189050.1 PFAM: isochorismatase hydrolase YP_001189051.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189052.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001189053.1 PFAM: cation transporter YP_001189054.1 PFAM: TrkA-N domain protein; TrkA-C domain protein YP_001189055.1 PFAM: globin YP_001189056.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001189058.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein, family 3 YP_001189059.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001189060.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001189062.1 PFAM: NnrS family protein YP_001189063.1 Regulatory factor involved in maltose metabolism YP_001189064.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II YP_001189065.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type YP_001189066.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001189068.1 TIGRFAM: PAS sensor protein; PFAM: Na+/solute symporter; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein YP_001189069.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001189070.1 TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region YP_001189071.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001189072.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001189073.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001189074.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001189075.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001189077.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001189078.1 PFAM: conserved hypothetical protein 95 YP_001189079.1 PFAM: protein of unknown function DUF748 YP_001189082.1 PFAM: CsbD family protein YP_001189083.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria YP_001189084.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001189085.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001189086.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001189087.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001189088.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001189089.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001189090.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001189091.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit YP_001189092.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001189093.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001189094.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001189095.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001189096.1 PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ YP_001189097.1 PFAM: protein of unknown function UPF0044 YP_001189099.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001189100.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001189101.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001189102.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001189103.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001189104.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001189105.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001189106.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein YP_001189107.1 PFAM: ferric-uptake regulator YP_001189108.1 PFAM: SmpA/OmlA domain protein YP_001189109.1 PFAM: protein of unknown function UPF0125 YP_001189110.1 PFAM: cyclase/dehydrase YP_001189111.1 PFAM: sodium:neurotransmitter symporter YP_001189112.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001189113.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001189114.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease YP_001189115.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001189116.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_001189117.1 PFAM: IS66 Orf2 family protein YP_001189118.1 PFAM: transposase IS66 YP_001189119.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001189120.1 PFAM: nitroreductase YP_001189121.1 PFAM: glutathione peroxidase YP_001189122.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001189124.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001189125.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001189126.1 PFAM: phospholipid/glycerol acyltransferase YP_001189127.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; SMART: PAS domain containing protein YP_001189128.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189129.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen YP_001189130.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen YP_001189131.1 PFAM: beta-lactamase domain protein YP_001189132.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001189135.1 PFAM: alpha/beta hydrolase fold YP_001189136.1 PFAM: regulatory protein, TetR YP_001189138.1 PFAM: regulatory protein, LuxR; SMART: AAA ATPase YP_001189139.1 PFAM: protein of unknown function DUF1329 YP_001189140.1 PFAM: protein of unknown function DUF1302 YP_001189141.1 activates fatty acids by binding to coenzyme A YP_001189142.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001189143.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001189144.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor YP_001189145.1 PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; Methyltransferase small, N-terminal domain protein YP_001189146.1 PFAM: protein of unknown function UPF0016 YP_001189147.1 PFAM: protein of unknown function DUF1486 YP_001189148.1 PFAM: peptidase M48, Ste24p YP_001189149.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001189150.1 PFAM: protein of unknown function DUF159 YP_001189152.1 PFAM: phospholipid/glycerol acyltransferase YP_001189157.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001189158.1 PFAM: CreA family protein YP_001189159.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001189160.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001189161.1 involved in the peptidyltransferase reaction during translation YP_001189162.1 PFAM: ribosomal protein L21 YP_001189163.1 PFAM: Polyprenyl synthetase YP_001189164.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001189165.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001189166.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001189167.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001189168.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001189169.1 PFAM: lipopolysaccharide kinase YP_001189172.1 PFAM: protein of unknown function DUF450 YP_001189173.1 PFAM: N-acetyltransferase YP_001189174.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001189175.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001189176.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189178.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease YP_001189179.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional regulator YcdC, C-terminal domain protein YP_001189180.1 PFAM: protein of unknown function UPF0029 YP_001189181.1 PFAM: protein of unknown function DUF922 YP_001189182.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001189184.1 PFAM: regulatory protein, MerR YP_001189185.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway. YP_001189186.1 catalyzes the formation of inosine from adenosine YP_001189187.1 PFAM: protein of unknown function DUF461 YP_001189189.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001189191.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189192.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001189194.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional repressor MAATS-type, C-terminal domain protein YP_001189195.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001189196.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001189197.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001189198.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001189199.1 TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001189201.1 PFAM: GCN5-related N-acetyltransferase YP_001189202.1 PFAM: histone deacetylase superfamily YP_001189203.1 PFAM: aminotransferase, class V YP_001189204.1 PFAM: HI0933 family protein YP_001189205.1 PFAM: response regulator receiver YP_001189206.1 PFAM: PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001189207.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001189208.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001189209.1 TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001189210.1 PFAM: protein of unknown function DUF88 YP_001189211.1 PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001189212.1 PFAM: protein of unknown function UPF0259 YP_001189213.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001189214.1 SMART: extracellular solute-binding protein, family 3 YP_001189215.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001189216.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001189218.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001189219.1 TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001189221.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001189222.1 PFAM: regulatory protein, AsnC/Lrp family YP_001189224.1 PFAM: globin YP_001189225.1 PFAM: pseudouridine synthase YP_001189226.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001189227.1 PFAM: GCN5-related N-acetyltransferase YP_001189228.1 PFAM: aminotransferase, class V; regulatory protein GntR, HTH; aminotransferase, class I and II YP_001189229.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001189230.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001189233.1 PFAM: carbonic anhydrase YP_001189234.1 TIGRFAM: CRISPR-associated protein Cas2 YP_001189235.1 TIGRFAM: CRISPR-associated protein Cas1 YP_001189236.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein, CT1974 YP_001189237.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5 YP_001189238.1 TIGRFAM: CRISPR-associated protein, Cse4 family YP_001189239.1 TIGRFAM: CRISPR-associated protein, Cse2 family YP_001189240.1 TIGRFAM: CRISPR-associated protein, Cse1 family YP_001189242.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system YP_001189243.1 TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein YP_001189244.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001189245.1 PFAM: regulatory protein, TetR YP_001189246.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001189247.1 PFAM: periplasmic binding protein YP_001189248.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001189249.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001189251.1 PFAM: major facilitator superfamily MFS_1 YP_001189252.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001189253.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_001189254.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001189256.1 PFAM: Sel1 domain protein repeat-containing protein YP_001189259.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001189260.1 PFAM: PhoH family protein YP_001189261.1 PFAM: protein of unknown function UPF0054 YP_001189262.1 PFAM: CBS domain containing protein; transporter-associated region YP_001189263.1 Transfers the fatty acyl group on membrane lipoproteins YP_001189264.1 PFAM: protein of unknown function DUF218 YP_001189266.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001189267.1 PFAM: Rare lipoprotein B YP_001189268.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001189269.1 PFAM: protein of unknown function DUF331 YP_001189270.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein YP_001189271.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001189272.1 TIGRFAM: lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase YP_001189273.1 PFAM: protein of unknown function DUF493 YP_001189274.1 PFAM: beta-lactamase; peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein YP_001189275.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein YP_001189276.1 TIGRFAM: lytic murein transglycosylase B YP_001189277.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein YP_001189278.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001189279.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001189280.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein YP_001189281.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001189282.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001189283.1 PFAM: alpha/beta hydrolase fold YP_001189285.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_001189286.1 PFAM: phosphoesterase, PA-phosphatase related YP_001189287.1 PFAM: peptidase S16, lon domain protein YP_001189288.1 PFAM: LrgB family protein YP_001189289.1 PFAM: LrgA family protein YP_001189290.1 PFAM: MaoC domain protein dehydratase YP_001189291.1 PFAM: MORN repeat-containing protein YP_001189292.1 PFAM: NAD-dependent epimerase/dehydratase YP_001189294.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001189295.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001189296.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189297.1 activates fatty acids by binding to coenzyme A YP_001189299.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001189300.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001189301.1 PFAM: beta-lactamase domain protein YP_001189302.1 PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001189303.1 PFAM: protein of unknown function DUF1375 YP_001189305.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein YP_001189306.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001189307.1 PFAM: GCN5-related N-acetyltransferase YP_001189308.1 PFAM: protein of unknown function DUF980 YP_001189309.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001189311.1 PFAM: gamma-glutamyltranspeptidase YP_001189312.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001189313.1 PFAM: amidohydrolase; Amidohydrolase 3 YP_001189314.1 PFAM: inner-membrane translocator; ABC transporter related; SMART: AAA ATPase YP_001189315.1 PFAM: inner-membrane translocator YP_001189316.1 PFAM: Extracellular ligand-binding receptor YP_001189318.1 PFAM: protein of unknown function DUF81 YP_001189319.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit YP_001189320.1 PFAM: Polyprenyl synthetase YP_001189321.1 PFAM: carboxyl transferase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001189322.1 PFAM: alpha/beta hydrolase fold YP_001189323.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001189324.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001189325.1 PFAM: periplasmic binding protein YP_001189327.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001189330.1 PFAM: phosphatidylglycerophosphatase A YP_001189331.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001189332.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001189333.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001189334.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis YP_001189335.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001189336.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001189337.1 PFAM: ATP-cone domain protein YP_001189339.1 PFAM: methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 12 YP_001189340.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001189343.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001189344.1 PFAM: protein of unknown function DUF214 YP_001189347.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein YP_001189348.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001189349.1 PFAM: MotA/TolQ/ExbB proton channel YP_001189350.1 PFAM: MotA/TolQ/ExbB proton channel YP_001189352.1 PFAM: OmpW family protein YP_001189353.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001189354.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase YP_001189355.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n YP_001189356.1 PFAM: major facilitator superfamily MFS_1 YP_001189357.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001189358.1 PFAM: peptidase M14, carboxypeptidase A YP_001189359.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein YP_001189360.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_001189361.1 PFAM: Na+/H+ antiporter NhaC YP_001189362.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001189363.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001189364.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001189365.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001189366.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001189367.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001189368.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001189369.1 late assembly protein YP_001189370.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001189371.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001189372.1 binds 5S rRNA along with protein L5 and L25 YP_001189373.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001189374.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001189375.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001189376.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001189377.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001189378.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001189379.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001189380.1 one of the stabilizing components for the large ribosomal subunit YP_001189381.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001189382.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001189383.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001189384.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001189385.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001189386.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001189387.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001189388.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001189389.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001189390.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001189391.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001189392.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001189393.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001189394.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001189395.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001189396.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001189397.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001189398.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001189399.1 binds directly to 23S ribosomal RNA YP_001189400.1 Modulates Rho-dependent transcription termination YP_001189401.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001189402.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001189403.1 PFAM: Sporulation domain protein YP_001189404.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001189405.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001189406.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001189407.1 PFAM: peptidase M23B; Opacity-associated protein A YP_001189408.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001189409.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001189410.1 PFAM: protein of unknown function DUF583 YP_001189412.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001189413.1 PFAM: conserved hypothetical protein 701 YP_001189414.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001189415.1 PFAM: alanine racemase domain protein YP_001189416.1 PFAM: protein of unknown function DUF805 YP_001189417.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001189418.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001189419.1 PFAM: protein of unknown function DUF323 YP_001189421.1 PFAM: OsmC family protein YP_001189422.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001189423.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001189424.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001189425.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001189427.1 PFAM: protein of unknown function DUF159 YP_001189449.1 TIGRFAM: phage major capsid protein, HK97 family; PFAM: phage major capsid protein, HK97 YP_001189450.1 PFAM: peptidase S14, ClpP YP_001189451.1 TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein YP_001189452.1 PFAM: phage Terminase YP_001189454.1 PFAM: HNH endonuclease YP_001189455.1 TIGRFAM: phage holin, lambda family; PFAM: Holin, phage lambda YP_001189457.1 PFAM: virulence-associated E family protein YP_001189461.1 PFAM: helix-turn-helix domain protein YP_001189462.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B YP_001189473.1 PFAM: Prophage CP4-57 regulatory YP_001189475.1 PFAM: phage integrase family protein YP_001189476.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001189477.1 TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001189478.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001189479.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189480.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189481.1 PFAM: extracellular solute-binding protein, family 1 YP_001189482.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001189483.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001189484.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein, family 3 YP_001189486.1 PFAM: heat shock protein DnaJ domain protein YP_001189487.1 PFAM: Nucleotidyl transferase YP_001189488.1 PFAM: aminoglycoside phosphotransferase YP_001189489.1 PFAM: OstA family protein; Organic solvent tolerance protein YP_001189490.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001189491.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001189492.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001189493.1 protein associated with Co2+ and Mg2+ efflux YP_001189494.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001189495.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_001189496.1 PFAM: PrkA serine kinase; PrkA AAA domain protein YP_001189497.1 PFAM: protein of unknown function DUF444 YP_001189498.1 PFAM: SpoVR family protein YP_001189500.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001189501.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001189502.1 TIGRFAM: dihydroneopterin aldolase YP_001189503.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001189504.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001189505.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001189506.1 synthesizes RNA primers at the replication forks YP_001189507.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001189508.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; extracellular solute-binding protein, family 3; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189510.1 PFAM: helix-turn-helix domain protein YP_001189511.1 PFAM: HipA domain protein YP_001189512.1 PFAM: NERD domain protein; DNA topoisomerase, type IA, zn finger domain protein YP_001189515.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase YP_001189516.1 PFAM: protein of unknown function DUF323 YP_001189517.1 PFAM: Methyltransferase type 12 YP_001189518.1 PFAM: protein of unknown function UPF0057 YP_001189519.1 PFAM: regulatory protein, LuxR; response regulator receiver; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001189520.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001189522.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001189523.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: C4-dicarboxylate anaerobic carrier; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001189524.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component YP_001189525.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001189526.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold-4 domain protein; SMART: AAA ATPase YP_001189527.1 PFAM: Gluconate transporter; Citrate transporter YP_001189528.1 PFAM: coenzyme A transferase YP_001189529.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001189530.1 catalyzes the formation of putrescine from agmatine YP_001189531.1 PFAM: extracellular solute-binding protein, family 1 YP_001189532.1 PFAM: helix-turn-helix- domain containing protein, AraC type; transcription activator, effector binding YP_001189533.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189535.1 PFAM: NADPH-dependent FMN reductase YP_001189536.1 PFAM: regulatory protein, TetR YP_001189538.1 PFAM: protein of unknown function DUF839 YP_001189539.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein YP_001189540.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001189541.1 PFAM: MotA/TolQ/ExbB proton channel YP_001189542.1 PFAM: phytase YP_001189543.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001189544.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001189545.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001189546.1 PFAM: Endonuclease I YP_001189547.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001189548.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001189549.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001189550.1 PFAM: nucleoside recognition domain protein YP_001189551.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_001189552.1 TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3 YP_001189553.1 PFAM: protein of unknown function DUF886 YP_001189554.1 PFAM: Na+/Pi-cotransporter YP_001189556.1 TIGRFAM: phosphate binding protein YP_001189557.1 PFAM: protein of unknown function DUF344 YP_001189558.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001189559.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001189560.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001189563.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001189564.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001189565.1 PFAM: alpha/beta hydrolase fold YP_001189566.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001189567.1 TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001189570.1 TIGRFAM: molybdate transport repressor, ModE; PFAM: regulatory protein, LysR; TOBE domain protein YP_001189571.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001189572.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane YP_001189573.1 PFAM: amino acid-binding ACT domain protein YP_001189574.1 PFAM: GCN5-related N-acetyltransferase YP_001189575.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001189576.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative YP_001189577.1 TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001189578.1 PFAM: peptidase U32 YP_001189580.1 PFAM: Na+/solute symporter YP_001189582.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001189584.1 TIGRFAM: alpha-1,6-glucosidase, pullulanase-type; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region YP_001189586.1 PFAM: Inner membrane CreD family protein YP_001189587.1 GbpA; plays a role mediating bacterial attachment and colonization of zooplankton and/or intestinal epithelium; in Vibrio cholerae this protein probably binds directly N-acetylglucosamine residues in chitin, glycoproteins and lipids on intestinal epithelial cells YP_001189588.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase domain protein YP_001189590.1 SMART: helicase c2 YP_001189593.1 PFAM: transposase IS66 YP_001189594.1 PFAM: IS66 Orf2 family protein YP_001189598.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_001189599.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_001189600.1 PFAM: CBS domain containing protein YP_001189601.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001189602.1 PFAM: protein of unknown function DUF785 YP_001189603.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001189604.1 PFAM: phospholipid/glycerol acyltransferase YP_001189605.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001189606.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001189607.1 TIGRFAM: sarcosine oxidase, gamma subunit family; PFAM: Sarcosine oxidase, gamma subunit YP_001189608.1 TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001189609.1 TIGRFAM: sarcosine oxidase, delta subunit family; PFAM: Sarcosine oxidase, delta subunit, heterotetrameric YP_001189610.1 TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase YP_001189611.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001189613.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001189614.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein YP_001189615.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001189616.1 PFAM: Rieske [2Fe-2S] domain protein YP_001189617.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001189618.1 Required for the synthesis of the thiazole moiety YP_001189619.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp YP_001189622.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001189623.1 TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001189624.1 PFAM: TM2 domain containing protein+B7201 YP_001189625.1 PFAM: Radical SAM domain protein YP_001189627.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001189628.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001189629.1 PFAM: alanine racemase domain protein YP_001189630.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001189631.1 PFAM: protein of unknown function YGGT YP_001189632.1 PFAM: protein of unknown function DUF167 YP_001189634.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_001189635.1 TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12 YP_001189637.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001189638.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001189639.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; Sporulation domain protein YP_001189641.1 PFAM: Carbohydrate-binding, CenC domain protein domain protein YP_001189644.1 PFAM: protein of unknown function DUF1329 YP_001189645.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001189646.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001189647.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein YP_001189648.1 PFAM: protein of unknown function DUF423 YP_001189649.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001189651.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001189652.1 PFAM: protein of unknown function DUF214 YP_001189653.1 TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001189654.1 TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001189655.1 PFAM: peptidase M16 domain protein YP_001189656.1 PFAM: peptidase M16 domain protein YP_001189657.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95 YP_001189659.1 PFAM: alpha/beta hydrolase fold YP_001189660.1 PFAM: Calcium/calmodulin dependent protein kinase II, association-domain protein YP_001189661.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001189662.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001189663.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189664.1 PFAM: response regulator receiver YP_001189665.1 PFAM: regulatory protein, TetR YP_001189666.1 PFAM: aldehyde dehydrogenase YP_001189668.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase YP_001189670.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001189671.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001189672.1 TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001189673.1 PFAM: Na+/Pi-cotransporter YP_001189675.1 PFAM: phospholipid/glycerol acyltransferase YP_001189676.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001189677.1 PFAM: HDOD YP_001189678.1 PFAM: putative RNA methylase YP_001189679.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001189681.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189682.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189684.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001189685.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase YP_001189686.1 TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001189687.1 PFAM: protein of unknown function DUF161 YP_001189688.1 PFAM: dihydrofolate reductase region YP_001189689.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_001189691.1 PFAM: GTP-binding protein, HSR1-related YP_001189692.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001189693.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001189694.1 PFAM: protein of unknown function DUF81 YP_001189695.1 PFAM: protein of unknown function DUF833 YP_001189696.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001189697.1 hydrolyzes diadenosine polyphosphate YP_001189698.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001189700.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001189702.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001189704.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001189705.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR YP_001189706.1 PFAM: SdiA-regulated domain protein YP_001189707.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; conserved hypothetical protein 156 YP_001189708.1 PFAM: SdiA-regulated domain protein YP_001189709.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001189710.1 PFAM: FAD linked oxidase domain protein YP_001189711.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001189712.1 PFAM: protein of unknown function DUF523 YP_001189714.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit YP_001189718.1 SMART: helix-turn-helix- domain containing protein, AraC type YP_001189719.1 PFAM: peptidase S45, penicillin amidase YP_001189721.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001189722.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001189723.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin YP_001189724.1 PFAM: Rhodanese domain protein YP_001189725.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001189726.1 PFAM: peptidase M23B YP_001189727.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001189728.1 SMART: extracellular solute-binding protein, family 3 YP_001189731.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001189732.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001189734.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001189735.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001189736.1 PFAM: FAD dependent oxidoreductase YP_001189737.1 PFAM: AsmA family protein YP_001189738.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein YP_001189739.1 PFAM: Fe(II) trafficking protein YggX YP_001189742.1 PFAM: ribonuclease H YP_001189745.1 PFAM: Resolvase, N-terminal domain YP_001189748.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001189749.1 PFAM: extracellular solute-binding protein, family 3 YP_001189750.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189751.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189754.1 PFAM: acyltransferase 3 YP_001189756.1 PFAM: virulence factor MVIN family protein YP_001189759.1 PFAM: glycosyl transferase, group 1 YP_001189760.1 PFAM: glycosyl transferase, group 1 YP_001189762.1 PFAM: glycosyl transferase, group 1 YP_001189763.1 PFAM: lipopolysaccharide biosynthesis protein YP_001189764.1 PFAM: polysaccharide export protein YP_001189765.1 PFAM: glycosyl transferase, family 2 YP_001189766.1 TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II; Nucleotidyl transferase; Cupin 2, conserved barrel domain protein YP_001189767.1 PFAM: sugar transferase YP_001189768.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001189769.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase YP_001189770.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001189771.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase YP_001189772.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001189773.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001189774.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001189775.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component YP_001189776.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit YP_001189777.1 PFAM: protein of unknown function DUF502 YP_001189778.1 PFAM: regulatory protein, AsnC/Lrp family YP_001189780.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; SMART: AAA ATPase YP_001189782.1 PFAM: band 7 protein YP_001189783.1 PFAM: protein of unknown function DUF107 YP_001189784.1 TIGRFAM: conserved hypothetical protein YP_001189785.1 PFAM: outer membrane porin YP_001189786.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189787.1 PFAM: fatty acid desaturase YP_001189788.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189789.1 PFAM: response regulator receiver; HDOD YP_001189790.1 TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189791.1 TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189792.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189793.1 PFAM: response regulator receiver YP_001189794.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; Hpt domain protein YP_001189795.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189796.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189797.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001189798.1 PFAM: TOBE domain protein YP_001189799.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001189800.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189801.1 catalyzes the release of sulfite from alkanesulfonates YP_001189802.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein, family 3 YP_001189803.1 PFAM: NADPH-dependent FMN reductase YP_001189804.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001189805.1 PFAM: GCN5-related N-acetyltransferase YP_001189806.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter YP_001189808.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001189809.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189810.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: ABC transporter, substrate-binding protein, aliphatic sulphonates; SMART: extracellular solute-binding protein, family 3 YP_001189811.1 PFAM: outer membrane porin YP_001189812.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein, family 3 YP_001189813.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001189814.1 PFAM: Rhodanese domain protein YP_001189815.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001189816.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1 YP_001189817.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001189818.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001189819.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189820.1 TIGRFAM: molybdate ABC transporter, ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase YP_001189821.1 PFAM: sigma-54 factor, interaction domain-containing protein; SMART: AAA ATPase YP_001189822.1 PFAM: protein of unknown function DUF1234 YP_001189824.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001189825.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189826.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component YP_001189827.1 TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001189829.1 PFAM: helix-turn-helix domain protein YP_001189831.1 PFAM: protein of unknown function DUF962 YP_001189832.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp YP_001189834.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_001189835.1 PFAM: outer membrane porin YP_001189836.1 PFAM: Tannase and feruloyl esterase YP_001189837.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold-4 domain protein; SMART: AAA ATPase YP_001189838.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit YP_001189839.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component YP_001189840.1 PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001189841.1 TIGRFAM: esterase, PHB depolymerase family YP_001189842.1 PFAM: major facilitator superfamily MFS_1 YP_001189843.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189844.1 PFAM: FAD dependent oxidoreductase YP_001189845.1 PFAM: glutamine synthetase, catalytic region YP_001189846.1 PFAM: chemotaxis sensory transducer YP_001189847.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001189848.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001189849.1 PFAM: fatty acid desaturase YP_001189850.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Diverse 7TM receptor, extracellular region 2; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001189851.1 PFAM: response regulator receiver; HDOD YP_001189852.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001189853.1 required for 70S ribosome assembly YP_001189854.1 PFAM: extracellular solute-binding protein, family 5 YP_001189855.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001189856.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001189857.1 catalyzes the formation of dUMP from dUTP YP_001189858.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001189859.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001189860.1 PFAM: thioesterase superfamily protein YP_001189862.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001189863.1 TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase YP_001189865.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001189866.1 PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732 YP_001189867.1 Essential for recycling GMP and indirectly, cGMP YP_001189868.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001189869.1 TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001189870.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP YP_001189872.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001189873.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001189874.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain YP_001189875.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189876.1 catalyzes branch migration in Holliday junction intermediates YP_001189877.1 PFAM: HDOD YP_001189880.1 PFAM: histone family protein DNA-binding protein YP_001189881.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001189882.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001189885.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001189886.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001189887.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001189888.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001189889.1 PFAM: Chorismate lyase YP_001189891.1 PFAM: Anti-sigma-28 factor, FlgM family protein YP_001189892.1 TIGRFAM: flagellar export protein FliJ YP_001189893.1 TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; SMART: AAA ATPase YP_001189894.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001189895.1 PFAM: flagellar motor switch protein FliG YP_001189896.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001189897.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE YP_001189898.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001189899.1 PFAM: surface presentation of antigens (SPOA) protein YP_001189900.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein YP_001189901.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001189902.1 PFAM: export protein FliQ, family 3 YP_001189903.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein YP_001189904.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001189905.1 TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein YP_001189907.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001189908.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001189909.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189910.1 PFAM: alanine dehydrogenase/PNT domain protein YP_001189912.1 PFAM: NAD(P) transhydrogenase, beta subunit YP_001189914.1 PFAM: protein of unknown function DUF1127 YP_001189915.1 TIGRFAM: conserved hypothetical protein YP_001189916.1 TIGRFAM: conserved hypothetical protein YP_001189918.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001189919.1 PFAM: Auxin Efflux Carrier YP_001189921.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E YP_001189922.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Pi-cotransporter YP_001189923.1 PFAM: Xanthine/uracil/vitamin C permease YP_001189924.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001189925.1 TIGRFAM: TRAP transporter solute receptor, TAXI family YP_001189926.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001189927.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001189929.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189930.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein YP_001189931.1 PFAM: luciferase family protein YP_001189932.1 PFAM: OsmC family protein YP_001189935.1 PFAM: protein of unknown function DUF1161 YP_001189936.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001189938.1 PFAM: GCN5-related N-acetyltransferase YP_001189940.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F YP_001189943.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001189944.1 PFAM: Bile acid:sodium symporter YP_001189945.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001189946.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001189947.1 PFAM: extracellular solute-binding protein, family 1 YP_001189948.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189949.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189950.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001189951.1 PFAM: Mannitol dehydrogenase, C-terminal domain; Mannitol dehydrogenase rossman, N-terminal domain YP_001189952.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase, FGGY YP_001189953.1 PFAM: PfkB domain protein YP_001189954.1 PFAM: carbonic anhydrase YP_001189956.1 PFAM: protein of unknown function DUF897 YP_001189957.1 catalyzes the formation of oxaloacetate from pyruvate YP_001189958.1 biotin carboxylase; with subunit B, the carboxyltansferase/biotincarboxyl carrier subunit catalyzes the formation of oxaloacetate from pyruvate YP_001189959.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189960.1 PFAM: protein of unknown function DUF182 YP_001189961.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001189962.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001189964.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS) YP_001189965.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001189966.1 PFAM: protein of unknown function DUF796 YP_001189967.1 PFAM: Rhs element Vgr protein YP_001189969.1 PFAM: Peptidoglycan-binding LysM YP_001189970.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001189972.1 PFAM: protein of unknown function DUF323 YP_001189973.1 PFAM: major facilitator superfamily MFS_1 YP_001189974.1 PFAM: periplasmic solute binding protein YP_001189976.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001189977.1 PFAM: ABC-3 protein YP_001189978.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001189980.1 PFAM: isochorismatase hydrolase YP_001189981.1 PFAM: Tetratricopeptide TPR_2 repeat protein YP_001189982.1 part of the metNIQ transport system for methionine YP_001189983.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001189984.1 PFAM: NLPA lipoprotein YP_001189985.1 PFAM: protein of unknown function DUF454 YP_001189986.1 PFAM: Haem oxygenase YP_001189987.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001189988.1 PFAM: FecR protein YP_001189989.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001189991.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001189992.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001189993.1 PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001189994.1 PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001189996.1 PFAM: import inner membrane translocase, subunit Tim44 YP_001189997.1 PFAM: GCN5-related N-acetyltransferase YP_001190002.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001190003.1 PFAM: aminotransferase class-III YP_001190004.1 PFAM: glutamine synthetase, catalytic region YP_001190007.1 PFAM: thioesterase superfamily protein YP_001190011.1 PFAM: alpha/beta hydrolase fold YP_001190012.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001190015.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001190016.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type YP_001190017.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_001190018.1 PFAM: phosphoribosyl-AMP cyclohydrolase YP_001190019.1 PFAM: protein of unknown function DUF37 YP_001190020.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001190021.1 PFAM: Hemolysin-type calcium-binding region; peptidase M10A and M12B, matrixin and adamalysin; SMART: peptidase, metallopeptidase YP_001190022.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative YP_001190023.1 3'-5' exonuclease of DNA polymerase III YP_001190025.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001190026.1 TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001190027.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter YP_001190030.1 PFAM: PAAR repeat-containing protein YP_001190031.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter YP_001190032.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001190034.1 PFAM: PepSY-associated TM helix domain protein YP_001190035.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001190038.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit YP_001190039.1 TIGRFAM: TRAP transporter solute receptor, TAXI family YP_001190040.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001190041.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001190042.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001190043.1 PFAM: transport system permease protein; inner-membrane translocator YP_001190044.1 PFAM: periplasmic binding protein YP_001190045.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001190046.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001190048.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_001190049.1 TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001190050.1 TIGRFAM: precorrin-3B synthase; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001190051.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_001190052.1 catalyzes the formation of precorrin-3 from precorrin-2 YP_001190053.1 TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein YP_001190054.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001190055.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001190056.1 PFAM: flavin reductase domain protein, FMN-binding YP_001190057.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001190058.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001190059.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001190060.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001190061.1 PFAM: GCN5-related N-acetyltransferase YP_001190062.1 catalyzes the formation of precorrin 6x from precorrin 5 YP_001190064.1 PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001190065.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_001190066.1 TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001190067.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein YP_001190068.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001190071.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24 YP_001190072.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001190073.1 PFAM: iron-containing alcohol dehydrogenase YP_001190074.1 PFAM: regulatory protein, IclR YP_001190076.1 PFAM: ANTAR domain protein YP_001190077.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001190078.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001190079.1 PFAM: transposase IS3/IS911 family protein YP_001190080.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001190081.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein YP_001190082.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001190083.1 TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001190084.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001190085.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001190086.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001190087.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001190088.1 TIGRFAM: ATP synthase F1, delta subunit; PFAM: H+-transporting two-sector ATPase, delta (OSCP) subunit YP_001190089.1 TIGRFAM: ATP synthase F0, B subunit; PFAM: H+-transporting two-sector ATPase, B/B' subunit YP_001190090.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001190091.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001190092.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_001190093.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease YP_001190094.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001190095.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001190096.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001190097.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001190098.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001190099.1 PFAM: protein of unknown function DUF37 YP_001190100.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001190101.1 PFAM: ribosomal protein L34